MORFIN Jean-François

email : jean-francois.morfin[remplacer_par_at]cnrs-orleans.fr

Téléphone : 02.38.25.56.05

Ingénieur de recherche en synthèse chimique au sein du groupe thématique “Complexes métalliques et IRM”

 



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25 documents

Article dans une revue

  • Saida Majdoub, Zoltán Garda, Alexandre Oliveira, Inga Relich, Agnes A. Pallier, et al.. Concentration‐dependent interactions of amphiphilic PiB‐ derivative metal complexes with amyloid peptides Aβ and amylin. Chemistry - A European Journal, 2021, 27, pp.2009-2020. ⟨10.1002/chem.202004000⟩. ⟨hal-03011656⟩
  • Alexandre Oliveira, Telma Costa, Licinia Justino, Rui Fausto, Jean-François Morfin, et al.. Photophysical studies on lanthanide( iii ) chelates conjugated to Pittsburgh compound B as luminescent probes targeted to Aβ amyloid aggregates. Photochemical & Photobiological Sciences , 2020, 19 (11), pp.1522-1537. ⟨10.1039/D0PP00214C⟩. ⟨hal-03011501⟩
  • Markus Bödenler, Kyangwi Malikidogo, Jean-François Morfin, Christoph Aigner, Éva Tóth, et al.. High‐Field Detection of biomarkers with Fast Field‐Cycling MRI: The Example of Zinc Sensing. Chemistry - A European Journal, 2019, ⟨10.1002/chem.201901157⟩. ⟨hal-02117697⟩
  • Pedro Miguel Costa, Julie Tzu-Wen Wang, Jean-François Morfin, Tamanna Khanum, Wan To, et al.. Functionalised Carbon Nanotubes Enhance Brain Delivery of Amyloid-Targeting Pittsburgh Compound B (PiB)-Derived Ligands. Nanotheranostics, 2018, 2 (2), pp.168-183. ⟨10.7150/ntno.23125⟩. ⟨hal-02080078⟩
  • Kyangwi Malikidogo, Isidro da Silva, Jean-François Morfin, Sara Lacerda, Laurent Barantin, et al.. A cocktail of 165 Er( iii ) and Gd( iii ) complexes for quantitative detection of zinc using SPECT and MRI. Chemical Communications, 2018, 54 (55), pp.7597 - 7600. ⟨10.1039/c8cc03407a⟩. ⟨hal-01904447⟩
  • S. Lacerda, J.-F. Morfin, C. F G C Geraldes, É. Tóth. Metal complexes for multimodal imaging of misfolded protein-related diseases. Dalton Transactions, 2017, 46 (42), pp.14461-14474. ⟨10.1039/C7DT02371E⟩. ⟨hal-02068723⟩
  • Jonathan Pansieri, Marie Plissonneau, Nathalie Stransky-Heilkron, Mireille Dumoulin, Laurence Heinrich-Balard, et al.. Multimodal imaging Gd-nanoparticles functionalized with Pittsburgh compound B or a nanobody for amyloid plaques targeting.. Nanomedicine, 2017, 12 (14), pp.1675-1687. ⟨10.2217/nnm-2017-0079⟩. ⟨hal-01561318⟩
  • D Cressier, M Dhilly, Tt Cao Pham, F Fillesoye, F Gourand, et al.. Gallium-68 Complexes Conjugated to Pittsburgh Compound B: Radiolabeling and Biological Evaluation. Molecular Imaging and Biology, 2016, 18 (3), pp.334-43. ⟨10.1007/s11307-015-0906-9⟩. ⟨hal-01575680⟩
  • André Martins, Alexandre Oliveira, Jean-François Morfin, Douglas Laurents, Éva Tóth, et al.. Associating a negatively charged GdDOTA-derivative to the Pittsburgh compound B for targeting Aβ amyloid aggregates. Journal of Biological Inorganic Chemistry, 2016, 21 (1), pp.83-99. ⟨10.1007/s00775-015-1316-9⟩. ⟨hal-02069097⟩
  • Marie Plissonneau, Jonathan Pansieri, Laurence Heinrich-Balard, Jean-François Morfin, Nathalie Stransky-Heilkron, et al.. Gd-nanoparticles functionalization with specific peptides for ß-amyloid plaques targeting.. Journal of Nanobiotechnology, 2016, 14 (1), pp.60. ⟨10.1186/s12951-016-0212-y⟩. ⟨hal-01356748⟩
  • André F. Martins, David M. Dias, Jean-François Morfin, Sara Lacerda, Douglas V. Laurents, et al.. Interaction of PiB-Derivative Metal Complexes with Beta-Amyloid Peptides: Selective Recognition of the Aggregated Forms. Chemistry - A European Journal, 2015, 21 (14), pp.5413-5422. ⟨10.1002/chem.201406152⟩. ⟨hal-01171718⟩
  • Jean-François Morfin, Jean-Claude Beloeil, Éva Tóth. Agents de contraste pour l'IRM. Techniques de l'Ingénieur, 2014, pp.AF6818-1 - AF6818-19. ⟨hal-01179490⟩
  • André F Martins, Jean-François Morfin, Carlos F G C Geraldes, Éva Tóth. Gd(3+) complexes conjugated to Pittsburgh compound B: potential MRI markers of β-amyloid plaques.. European Journal of Biochemistry, 2014, 19 (2), pp.281-295. ⟨hal-01179355⟩
  • Célia S. Bonnet, Fabien Caillé, Agnès Pallier, Jean-François Morfin, Stéphane Petoud, et al.. Mechanistic studies of Gd$^{3+}$-based MRI contrast agents for Zn$^{2+}$ detection: towards rational design. Chemistry - A European Journal, 2014, 20 (35), pp.10959-10969. ⟨10.1002/chem.201403043⟩. ⟨hal-01178456⟩
  • André F. Martins, Jean-François Morfin, Anna Kubícková, Vojtěch Kubícek, Frédéric Buron, et al.. PiB-Conjugated, Metal-Based Imaging Probes: Multimodal Approaches for the Visualization of β-Amyloid Plaques. Planetary and Space Science, 2013, 4 (5), pp.436-440. ⟨10.1021/ml400042w⟩. ⟨hal-00840181⟩
  • Luis M.P Lima, Alexandre Lecointre, Jean-François Morfin, Andres de Blas, Dimitris Visvikis, et al.. Positively Charged Lanthanide Complexes with Cyclen-Based Ligands : Synthesis, Solid-State and Solution Structure, and Fluoride Interaction. Inorganic Chemistry, 2011, 50 (24), pp.12508-12521. ⟨10.1021/ic201447c⟩. ⟨hal-00703687⟩
  • Jean-François Morfin, Éva Tóth. Kinetics of Ga(NOTA) formation from weak Ga-citrate complexes.. Inorganic Chemistry, 2011, 50 (20), pp.10371-8. ⟨10.1021/ic201445e⟩. ⟨hal-00720677⟩
  • Raphaël Tripier, Carlos Platas-Iglesias, Anne Boos, Jean-François Morfin, Loïc Charbonnière. Towards Fluoride Sensing with Positively Charged Lanthanide Complexes. European Journal of Inorganic Chemistry, 2010, 2010 (18), pp.2735 - 2745. ⟨10.1002/ejic.200901045⟩. ⟨hal-01577344⟩
  • Jean-François Morfin, Raphaël Tripier, Michel Le Baccon, Henri Handel. Bismuth (III) coordination to cyclen and cyclam bearing four appended groups. Polyhedron, 2009, 28 (17), pp.3691 - 3698. ⟨10.1016/j.poly.2009.08.003⟩. ⟨hal-01580260⟩
  • Jean-François Morfin, Raphaël Tripier, Michel Le Baccon, Henri Handel. Bismuth(III) complexes with tetra-pyridylmethyl-cyclen. Inorganica Chimica Acta Reviews, 2009, 362 (6), pp.1781 - 1786. ⟨10.1016/j.ica.2008.08.013⟩. ⟨hal-01580209⟩

Poster

  • Kyangwi Malikidogo, I. da Silva, Jean-François Morfin, S. Lacerda, Laurent Barantin, et al.. SPECT / MRI quantitative detection of zinc using a cocktail of 165Er(III) and Gd(III) complexes. 14th European Molecular Imaging Meeting, Mar 2019, Glasgow, United Kingdom. ⟨hal-03292258⟩
  • P. Malikidogo K., Jean-François Morfin, S. Lacerda, I. da Silva, Laurent Barantin, et al.. MRI contrast agents for quantitative zinc detection. GDR Agents d’Imagerie Moléculaire (AIM), Jun 2018, Orléans, France. ⟨hal-03296044⟩
  • Kyangwi Malikidogo, Agnes A. Pallier, Jean-François Morfin, Éva Tóth, Celia ́ Bonnet. Smart MRI contrast agents for zinc detection. Le Studium conférence “Being smart in coordination chemistry: Medical Applications”, Sep 2016, Orléans, France. ⟨hal-03300683⟩
  • Kyangwi Malikidogo, Agnes A. Pallier, Jean-François Morfin, Éva Tóth, Celia ́ Bonnet. Zinc responsive contrast agents. International Conference on Coordination Chemistry (ICCC), Jul 2016, Brest, France. ⟨hal-03300659⟩
  • Kyangwi Malikidogo, Agnes A. Pallier, Jean-François Morfin, Éva Tóth, Celia ́ Bonnet. Smart MRI contrast agents for zinc detection. Colloque association des doctorants du CBM, Feb 2016, Orléans, France. ⟨hal-03300628⟩