MicroRNAs (miRNAs) are key regulatory elements encoded by the genome. A single miRNA can downregulate the expression of multiple genes involved in diverse functions. Because cancer is a disease with multiple gene aberrations, developing novel approaches to identify and modulate miRNA pathways may result in a breakthrough for cancer treatment. With a special focus on glioblastoma (GBM), this review provides an up-to-date summary of miRNA biogenesis, the role of miRNA in cancer resistance, and essential tools for modulating miRNA expression, as well as of clinically promising RNAi delivery systems and how they can be adapted for therapy.
A lire aussi
2024 May, 7 - El Hadji Cisse Defensis
23 April 2024
par Laetitia Legoupil
July 1st-3rd "Skin Models in Cosmetic Science: Bridging Established Methods and Novel Technologies" - 3rd meeting
23 April 2024
par Laetitia Legoupil
2024, May 24 - Seminar of Frank Schreiber
16 April 2024
par Laetitia Legoupil