LOTH Karine

email : karine.loth@cnrs-orleans.fr

Phone : +33 2.38.25.55.71

Office D125

Lecturer within the  thematic group “NMR of biomolecules



35 documents

Article dans une revue

  • Karine Loth, Justine Largillière, Franck Coste, Françoise Culard, Céline Landon, et al.. New protein-DNA complexes in archaea: a small monomeric protein induces a sharp V-turn DNA structure. Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-50211-2⟩. ⟨hal-02306224⟩
  • Karine Loth, Agnès Vergnes, Cairé Barreto, Sébastien Voisin, Hervé Meudal, et al.. The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets. mBio, American Society for Microbiology, 2019, 10 (5), pii: e01821-19. ⟨10.1128/mBio.01821-19⟩. ⟨hal-02328576⟩
  • Fabien Kieken, Karine Loth, Nico van Nuland, Peter Tompa, Tom Lenaerts. Chemical shift assignments of the partially deuterated Fyn SH2–SH3 domain. Biomolecular NMR Assignments, Springer, 2018, 12 (1), pp.117-122. ⟨hal-01966149⟩
  • Fabien Kieken, Karine Loth, Nico van Nuland, Peter Tompa, Tom Lenaerts. Chemical shift assignments of the partially deuterated Fyn SH2–SH3 domain. Biomolecular NMR Assignments, Springer, 2017, ⟨10.1007/s12104-017-9792-1⟩. ⟨hal-01673443⟩
  • Karine Loth, Soha Abou Ibrahim Alami, Chahrazed Habès, Solène Garrido, Vincent Aucagne, et al.. Complete 1H, 15N and 13C assignment of trappin-2 and 1H assignment of its two domains, elafin and cementoin. Biomolecular NMR Assignments, Springer, 2016, 10 (1), pp.223 - 226. ⟨10.1007/s12104-016-9671-1⟩. ⟨hal-01407495⟩
  • Geoffrey Bailleul, Amanda Kravtzoff, Alix Joulin-Giet, Fabien Lecaille, Valérie Labas, et al.. The unusual resistance of avian defensin AvBD7 to proteolytic enzymes preserves its antibacterial activity. PLoS ONE, Public Library of Science, 2016, 11 (8), pp.1-20. ⟨10.1371/journal.pone.0161573⟩. ⟨hal-01594888⟩
  • Karine Loth, Denis Costechareyre, Géraldine Effantin, Yvan Rahbé, Guy Condemine, et al.. New Cyt-like δ-endotoxins from Dickeya dadantii: structure and aphicidal activity.. Scientific Reports, Nature Publishing Group, 2015, 5, pp.8791. ⟨10.1038/srep08791⟩. ⟨hal-01124447⟩
  • Rémy Le Meur, Karine Loth, Françoise Culard, Bertrand Castaing, Céline Landon. Backbone assignment of the three dimers of HU from Escherichia coli at 293 K: EcHUα2, EcHUβ2 and EcHUαβ. Biomolecular NMR Assignments, Springer, 2015, 9 (2), pp.359-363. ⟨10.1007/s12104-015-9610-6⟩. ⟨hal-01171467⟩
  • Karine Loth, Céline Landon, Françoise Paquet. Chemical shifts assignments of the archaeal MC1 protein and a strongly bent 15 base pairs DNA duplex in complex. Biomolecular NMR Assignments, Springer, 2015, 9 (1), pp.215-217. ⟨10.1007/s12104-014-9577-8⟩. ⟨hal-01171478⟩
  • R. Le Meur, Françoise Culard, V. Nadan, S. Goffinont, F. Coste, et al.. The nucleoid-associated protein HU enhances 8-oxoguanine base excision by the formamidopyrimidine-DNA glycosylase. Biochemical Journal, Portland Press, 2015, 471 (1), pp.13-23. ⟨10.1042/BJ20150387⟩. ⟨hal-01216639⟩
  • Fanny Meindre, Dominique Lelièvre, Karine Loth, Oriane Mith, Vincent Aucagne, et al.. The nuclear magnetic resonance solution structure of the synthetic AhPDF1.1b plant defensin evidences the structural feature within the γ-motif. Biochemistry, American Chemical Society, 2014, 53 (49), pp.7745-54. ⟨10.1021/bi501285k⟩. ⟨hal-01118914⟩
  • Françoise Paquet, Olivier Delalande, Stephane Goffinont, Françoise Culard, Karine Loth, et al.. Model of a DNA-protein complex of the architectural monomeric protein MC1 from Euryarchaea. PLoS ONE, Public Library of Science, 2014, 9 (2), pp.e88809. ⟨10.1371/journal.pone.0088809⟩. ⟨hal-01063974⟩
  • Karine Loth, Manuel Gnida, Julija Romanuka, Robert Kaptein, Rolf Boelens. Sliding and target location of DNA-binding proteins:an NMR view of the lac repressor system.. Journal of Biomolecular NMR, Springer Verlag, 2013, epub ahead of print. ⟨10.1007/s10858-013-9723-0⟩. ⟨hal-00817496⟩
  • Norbert Garnier, Karine Loth, Franck Coste, Rafal Augustyniak, Virginie Nadan, et al.. An alternative flexible conformation of the E. coli HU beta(2) protein: structural, dynamics, and functional aspects. European Biophysics Journal, Springer Verlag (Germany), 2011, 40 (2), pp.117-129. ⟨10.1007/s00249-010-0630-y⟩. ⟨hal-00602370⟩
  • Mickaël Krzeminski, Karine Loth, Rolf Boelens, Alexandre Bonvin. SAMPLEX: automatic mapping of perturbed and unperturbed regions of proteins and complexes.. BMC Bioinformatics, BioMed Central, 2010, 11 (1), pp.51. ⟨10.1186/1471-2105-11-51⟩. ⟨inserm-00663535⟩
  • Françoise Paquet, Karine Loth, Hervé Meudal, Francoise Culard, Daniel Genest, et al.. Refined solution structure and backbone dynamics of the archaeal MC1 protein. FEBS Journal, Wiley, 2010, 277 (24), pp.5133-5145. ⟨10.1111/j.1742-4658.2010.07927.x⟩. ⟨hal-00602469⟩
  • Karine Loth, Daniel Abergel, Philippe Pelupessy, Marc Delarue, Philippe Lopes, et al.. Determination of dihedral Psi angles in large proteins by combining NH(N)/C(alpha)H(alpha) dipole/dipole cross-correlation and chemical shifts. Proteins - Structure, Function and Bioinformatics, Wiley, 2006, 64 (4), pp.931-939. ⟨10.1002/prot.21063⟩. ⟨hal-00103645⟩
  • Chiara Perazzolo, Julien Wist, Karine Loth, Luisa Poggi, Steve Homans, et al.. Effects of Protein–pheromone Complexation on Correlated Chemical Shift Modulations. Journal of Biomolecular NMR, Springer Verlag, 2006, 33 (4), pp.233-242. ⟨10.1007/s10858-005-3355-y⟩. ⟨hal-02128146⟩
  • Karine Loth, Philippe Pelupessy, Geoffrey Bodenhausen. Chemical Shift Anisotropy Tensors of Carbonyl, Nitrogen, and Amide Proton Nuclei in Proteins through Cross-Correlated Relaxation in NMR Spectroscopy. Journal of the American Chemical Society, American Chemical Society, 2005, 127 (16), pp.6062-6068. ⟨10.1021/ja042863o⟩. ⟨hal-02128145⟩
  • Federico Cisnetti, Karine Loth, Philippe Pelupessy, Geoffrey Bodenhausen. Determination of Chemical Shift Anisotropy Tensors of Carbonyl Nuclei in Proteins through Cross-Correlated Relaxation in NMR. ChemPhysChem, Wiley-VCH Verlag, 2004, 5 (6), pp.807-814. ⟨10.1002/cphc.200301041⟩. ⟨hal-02128143⟩
  • Karine Loth, Philippe Pelupessy, Geoffrey Bodenhausen. Cross-correlation between a carbonyl C ' chemical shift anisotropy and a long-range dipolar C ' HA coupling in proteins using symmetrical reconversion. Journal of Biomolecular NMR, Springer Verlag, 2003, 27 (2), pp.159-163. ⟨10.1023/A:1024979511837⟩. ⟨hal-02128142⟩

Communication dans un congrès

  • Justine Largillière, Rémy Le Meur, David Guiguène, Norbert Garnier, Celine Landon, et al.. Vers une description cinétique et structurale complète du mécanisme d'échange de chaînes de la protéine HU d'Escherichia coli.. GERM 2019, May 2019, Oléron, France. ⟨hal-02361645⟩

Poster

  • Justine Largillière, Rémy Le Meur, David Guinguène, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system.. Journée Fédération de recherche “Physique et Chimie du Vivant”, Apr 2019, Orléans, France. ⟨hal-02362578⟩
  • Justine Largillière, Rémy Le Meur, David Guinguène, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system.. NMR : a tool for biology XITh, Jan 2019, Paris, France. ⟨hal-02362588⟩
  • Justine Largillière, Rémy Le Meur, Martine Cadene, Bertrand Castaing, Karine Loth, et al.. Premières études cinétiques du mécanisme d’échange de chaînes de la protéine HU d’Escherischia coli.. Journée Fédération de recherche “Physique et Chimie du Vivant”, Jan 2018, Orléans, France. ⟨hal-02362577⟩
  • Justine Largillière, Rémy Le Meur, Martine Cadene, Bertrand Castaing, Karine Loth, et al.. Premières études cinétiques du mécanisme d’échange de chaînes de la protéine HU d’Escherischia coli.. 16e colloque scientifique de l’ADOC : Converger pour Renforcer, Apr 2018, Orléans, France. ⟨hal-02362579⟩
  • Karine Loth, Justine Largillière, Franck Coste, Françoise Culard, Celine Landon, et al.. New protein-DNA complexes in archaea: a small monomeric protein induces a sharp V-turn DNA structure.. EuroMar 2018, Jul 2018, Nantes, France. ⟨hal-02362581⟩
  • Karine Loth, Justine Largillière, Franck Coste, Françoise Culard, Bertrand Castaing, et al.. New protein-DNA complexes in archaea: a small monomeric protein induces a V-turn structure.. XXVIII ICMRBS 2018, Aug 2018, Dublin, Ireland. ⟨hal-02362584⟩
  • Justine Largillière, Rémy Le Meur, Norbert Garnier, Celine Landon, A.F. Delmas, et al.. Native and Intermediate conformations of the three HU dimers of E.coli.. XXVIII ICMRBS 2018, Aug 2018, Dublin, Ireland. ⟨hal-02362585⟩
  • Justine Largillière, Rémy Le Meur, David Guinguène, Celine Landon, A.F. Delmas, et al.. First kinetics description of the EcHU chain exchange system.. XXVIII ICMRBS 2018, Aug 2018, Dublin, Ireland. ⟨hal-02362586⟩
  • Karine Loth, Françoise Culard, Justine Largillière, Celine Landon, Bertrand Castaing, et al.. New protein-DNA complexes in archaea: a monomeric protein induces a U-turn structure.. 5e séminaire scientifique du LIA MiR-TANGo, May 2018, Orléans, France. ⟨hal-02362804⟩
  • Justine Largillière, Rémy Le Meur, David Guinguène, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system.. 31e colloque Biotechnocentre, Oct 2018, Seillac, France. ⟨hal-02362818⟩
  • Karine Loth, Françoise Culard, Justine Largillière, Celine Landon, Bertrand Castaing, et al.. The MC1-DNA complex solution structure reveals that a monomeric protein can induce a U-turn in archaea.. NMR: a tool for biology XTh, Jan 2017, Paris, France. ⟨hal-02361613⟩
  • Justine Largillière, Rémy Le Meur, Martine Cadene, Bertrand Castaing, Karine Loth, et al.. Première description cinétique du mécanisme d’échange de chaînes de la protéine HU d'Escherichia coli.. 30ème colloque Biotechnocentre, Oct 2017, Seillac, France. ⟨hal-02361632⟩
  • Karine Loth, Justine Largillière, Franck Coste, Françoise Culard, A.F. Delmas, et al.. New protein-DNA complexes in archaea: a monomeric protein induces a U-turn structure.. Structural biology and biophysics of RNA-protein complexes, Nov 2017, Orléans, France. ⟨hal-02362576⟩