LOTH Karine

email : karine.loth[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.55.71

Lecturer, thematic group  “NMR of biomolecules“


56 documents

Article dans une revue24 documents

  • Fatima Diya, Laurence Jouvensal, Isabelle Rahioui, Karine Loth, Catherine Sivignon, et al.. Residues of Legume AG41 Peptide Crucial to Its Bio-Insecticidal Activity. Biomolecules, 2023, 13 (3), pp.446. ⟨10.3390/biom13030446⟩. ⟨hal-04045320⟩
  • Valentine Barassé, Laurence Jouvensal, Guillaume Boy, Arnaud Billet, Steven Ascoët, et al.. Discovery of an Insect Neuroactive Helix Ring Peptide from Ant Venom. Toxins, 2023, 15 (10), pp.600. ⟨10.3390/toxins15100600⟩. ⟨hal-04390519⟩
  • Karine Loth, Nicolas Parisot, Françoise Paquet, Hugo Terrasson, Catherine Sivignon, et al.. Aphid BCR4 Structure and Activity Uncover a New Defensin Peptide Superfamily. International Journal of Molecular Sciences, 2022, 23 (20), pp.12480. ⟨10.3390/ijms232012480⟩. ⟨hal-03862651⟩
  • Nicolas Guyot, Sascha Trapp, Herve Meudal, Sophie Iochmann, Anne Silvestre, et al.. Structure, function, and evolution of Gga -AvBD11, the archetype of the structural avian-double-β-defensin family. Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (1), pp.337-345. ⟨10.1073/pnas.1912941117⟩. ⟨hal-02522250⟩
  • Karine Loth, Agnès Vergnes, Cairé Barreto, Sébastien N Voisin, Hervé Meudal, et al.. The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets. mBio, 2019, 10 (5), pii: e01821-19. ⟨10.1128/mBio.01821-19⟩. ⟨hal-02328576⟩
  • Karine Loth, Justine Largillière, Franck Coste, Françoise Culard, Céline Landon, et al.. New protein-DNA complexes in archaea: a small monomeric protein induces a sharp V-turn DNA structure. Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-50211-2⟩. ⟨hal-02306224⟩
  • Fabien Kieken, Karine Loth, Nico van Nuland, Peter Tompa, Tom Lenaerts. Chemical shift assignments of the partially deuterated Fyn SH2–SH3 domain. Biomolecular NMR Assignments, 2017, ⟨10.1007/s12104-017-9792-1⟩. ⟨hal-01673443⟩
  • Geoffrey Bailleul, Amanda Kravtzoff, Alix Joulin-Giet, Fabien Lecaille, Valérie Labas, et al.. The unusual resistance of avian defensin AvBD7 to proteolytic enzymes preserves its antibacterial activity. PLoS ONE, 2016, 11 (8), pp.1-20. ⟨10.1371/journal.pone.0161573⟩. ⟨hal-01594888⟩
  • Karine Loth, Soha Abou Ibrahim Alami, Chahrazed Habès, Solène Garrido, Vincent Aucagne, et al.. Complete 1H, 15N and 13C assignment of trappin-2 and 1H assignment of its two domains, elafin and cementoin. Biomolecular NMR Assignments, 2016, 10 (1), pp.223 - 226. ⟨10.1007/s12104-016-9671-1⟩. ⟨hal-01407495⟩
  • Karine Loth, Céline Landon, Françoise Paquet. Chemical shifts assignments of the archaeal MC1 protein and a strongly bent 15 base pairs DNA duplex in complex. Biomolecular NMR Assignments, 2015, 9 (1), pp.215-217. ⟨10.1007/s12104-014-9577-8⟩. ⟨hal-01171478⟩
  • Karine Loth, Denis Costechareyre, Géraldine Effantin, Yvan Rahbé, Guy Condemine, et al.. New Cyt-like δ-endotoxins from Dickeya dadantii: structure and aphicidal activity.. Scientific Reports, 2015, 5, pp.8791. ⟨10.1038/srep08791⟩. ⟨hal-01124447⟩
  • R. Le Meur, Françoise Culard, V. Nadan, S. Goffinont, F. Coste, et al.. The nucleoid-associated protein HU enhances 8-oxoguanine base excision by the formamidopyrimidine-DNA glycosylase. Biochemical Journal, 2015, 471 (1), pp.13-23. ⟨10.1042/BJ20150387⟩. ⟨hal-01216639⟩
  • Rémy Le Meur, Karine Loth, Françoise Culard, Bertrand Castaing, Céline Landon. Backbone assignment of the three dimers of HU from Escherichia coli at 293 K: EcHUα2, EcHUβ2 and EcHUαβ. Biomolecular NMR Assignments, 2015, 9 (2), pp.359-363. ⟨10.1007/s12104-015-9610-6⟩. ⟨hal-01171467⟩
  • Fanny Meindre, Dominique Lelièvre, Karine Loth, Oriane Mith, Vincent Aucagne, et al.. The nuclear magnetic resonance solution structure of the synthetic AhPDF1.1b plant defensin evidences the structural feature within the γ-motif. Biochemistry, 2014, 53 (49), pp.7745-54. ⟨10.1021/bi501285k⟩. ⟨hal-01118914⟩
  • Françoise Paquet, Olivier Delalande, Stephane Goffinont, Françoise Culard, Karine Loth, et al.. Model of a DNA-protein complex of the architectural monomeric protein MC1 from Euryarchaea. PLoS ONE, 2014, 9 (2), pp.e88809. ⟨10.1371/journal.pone.0088809⟩. ⟨hal-01063974⟩
  • Karine Loth, Manuel Gnida, Julija Romanuka, Robert Kaptein, Rolf Boelens. Sliding and target location of DNA-binding proteins:an NMR view of the lac repressor system.. Journal of Biomolecular NMR, 2013, epub ahead of print. ⟨10.1007/s10858-013-9723-0⟩. ⟨hal-00817496⟩
  • Norbert Garnier, Karine Loth, Franck Coste, Rafal Augustyniak, Virginie Nadan, et al.. An alternative flexible conformation of the E. coli HU beta(2) protein: structural, dynamics, and functional aspects. European Biophysics Journal, 2011, 40 (2), pp.117-129. ⟨10.1007/s00249-010-0630-y⟩. ⟨hal-00602370⟩
  • Françoise Paquet, Karine Loth, Hervé Meudal, Francoise Culard, Daniel Genest, et al.. Refined solution structure and backbone dynamics of the archaeal MC1 protein. FEBS Journal, 2010, 277 (24), pp.5133-5145. ⟨10.1111/j.1742-4658.2010.07927.x⟩. ⟨hal-00602469⟩
  • Mickaël Krzeminski, Karine Loth, Rolf Boelens, Alexandre Bonvin. SAMPLEX: automatic mapping of perturbed and unperturbed regions of proteins and complexes.. BMC Bioinformatics, 2010, 11 (1), pp.51. ⟨10.1186/1471-2105-11-51⟩. ⟨inserm-00663535⟩
  • Chiara Perazzolo, Julien Wist, Karine Loth, Luisa Poggi, Steve Homans, et al.. Effects of Protein–pheromone Complexation on Correlated Chemical Shift Modulations. Journal of Biomolecular NMR, 2006, 33 (4), pp.233-242. ⟨10.1007/s10858-005-3355-y⟩. ⟨hal-02128146⟩
  • Karine Loth, Daniel Abergel, Philippe Pelupessy, Marc Delarue, Philippe Lopes, et al.. Determination of dihedral Psi angles in large proteins by combining NH(N)/C(alpha)H(alpha) dipole/dipole cross-correlation and chemical shifts. Proteins - Structure, Function and Bioinformatics, 2006, 64 (4), pp.931-939. ⟨10.1002/prot.21063⟩. ⟨hal-00103645⟩
  • Karine Loth, Philippe Pelupessy, Geoffrey Bodenhausen. Chemical Shift Anisotropy Tensors of Carbonyl, Nitrogen, and Amide Proton Nuclei in Proteins through Cross-Correlated Relaxation in NMR Spectroscopy. Journal of the American Chemical Society, 2005, 127 (16), pp.6062-6068. ⟨10.1021/ja042863o⟩. ⟨hal-02128145⟩
  • Federico Cisnetti, Karine Loth, Philippe Pelupessy, Geoffrey Bodenhausen. Determination of Chemical Shift Anisotropy Tensors of Carbonyl Nuclei in Proteins through Cross-Correlated Relaxation in NMR. ChemPhysChem, 2004, 5 (6), pp.807-814. ⟨10.1002/cphc.200301041⟩. ⟨hal-02128143⟩
  • Karine Loth, Philippe Pelupessy, Geoffrey Bodenhausen. Cross-correlation between a carbonyl C ' chemical shift anisotropy and a long-range dipolar C ' HA coupling in proteins using symmetrical reconversion. Journal of Biomolecular NMR, 2003, 27 (2), pp.159-163. ⟨10.1023/A:1024979511837⟩. ⟨hal-02128142⟩

Communication dans un congrès6 documents

  • A. Asokan, Noémie de San Nicolas, H. Meudal, K. Loth, Delphine Destoumieux-Garzon, et al.. Enabling the synthesis of hydrophobic proteins using NCL-labile solubilizing tags: a case study of Crassostrea gigas big defensin 3. 22nd GFPP / BPGM5 French-Belgian Joint Meeting, Groupe Français des Peptides et Protéines, May 2022, Port Leucate, France. ⟨hal-03976595⟩
  • Hugo Terrasson, Karine Loth, Nicolas Parisot, Isabelle Rahioui, Karen Gaget, et al.. Peptides « Bacteriocyte-specific Cysteine Rich » (BCR) : un rôle dans le contrôle de la symbiose ? Focus sur BCR4 chez le puceron du pois. 12. Rencontre du Réseau Français de Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), May 2022, Nice, France. ⟨hal-03741305⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. Architecture et dynamique de protéines histone-like de bactérie et d’archées. Journée BioRMN IdF, Sep 2020, Gif-sur-Yvette, France. ⟨hal-03053296⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. Vers une description cinétique et structurale complète du mécanisme d'échange de chaînes de la protéine HU d'Escherichia coli.. XXXIe congrès du GERM (Groupement d'Etudes de Résonance Magnétique), May 2019, Oléron, France. ⟨hal-02361645⟩
  • H. Meudal, Nicolas Guyot, K. Loth, G. Jousset, S. Trapp, et al.. Gga-AvBD11, the archetype of a new structural family of defensins. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02892790⟩
  • Nicolas Guyot, Hervé Meudal, Karine Loth, Guillaume Jousset, Anne Silvestre, et al.. 1ère structure 3D d’une défensine à double motif β-défensine, Gga-AvBD11 du poulet Gallus gallus, et explorations fonctionnelles. 5es Journées GDR MuFoPAM, Centre National de la Recherche Scientifique (CNRS). FRA., Oct 2018, Paris, France. ⟨hal-02788993⟩

Poster26 documents

  • Hugo Terrasson, Karine Loth, Nicolas Parisot, Isabelle Rahioui, Karen Gaget, et al.. Bacteriocyte-specific Cystein-Rich (BCR) peptides, a new aphid’s defensin-like family, are promising regulators of aphid symbiosis. 10. Congress of the International Society of Symbiosis, Jul 2022, Lyon, France. ⟨hal-03741331⟩
  • David Gosset, Julien Sobilo, Herve Meudal, Frederic Szeremeta, Marylène Bertrand, et al.. Plateforme MO2VING: from MOlecular Organization to in Vivo ImagiNG. 34ème Colloque Biotechnocentre, Oct 2022, Nouan Le Fuzelier, France. ⟨hal-03863246⟩
  • Herve Meudal, Françoise Paquet, Laurence Jouvensal, V. Aucagne, A.F. Delmas, et al.. Chemical synthesis and natural abundance NMR: an efficient tandem to unravel 3D structures of unlabeled disulfide rich peptides. 21e congrès du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02919180⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system.. Journée Fédération de recherche “Physique et Chimie du Vivant”, Apr 2019, Orléans, France. ⟨hal-02362578⟩
  • Françoise Paquet, K. Loth, C. Arnoult, V. Aucagne, A.F. Delmas. Spermaurin, a scorpion venom disulfide-rich miniprotein that improves sperm motility and fertilization in mammals.. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02893462⟩
  • H. Meudal, K. Loth, G. Jousset, V. Aucagne, Nicolas Guyot, et al.. A new structural family for antimicrobial defensins. NMR : a tool for biology XIth, Jan 2019, Paris, France. ⟨hal-02919171⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system. NMR : a tool for biology XITh, Jan 2019, Paris, France. ⟨hal-02362588⟩
  • L. Jouvensal, K. Loth, A.F. Delmas, J. Orlans, C. Sivignon, et al.. Legume AG41 peptide: a promising bio-insecticide. 21e congrès du Groupe Français des Peptides et des Protéines (GFPP), May 2019, Amboise, France. ⟨hal-02919178⟩
  • Laurence Jouvensal, K. Loth, A.F. Delmas, I. Rahioui, P. Sivignon, et al.. A new legume bio-insecticide peptide. VIes journées annuelles du GDR MuFoPAM, Oct 2019, Besançon, France. ⟨hal-02919908⟩
  • Justine Largillière, Rémy Le Meur, Norbert Garnier, Celine Landon, A.F. Delmas, et al.. Native and Intermediate conformations of the three HU dimers of E.coli.. 28th ICMRBS - International Council on Magnetic Resonance in Biological Systems, Aug 2018, Dublin, Ireland. ⟨hal-02362585⟩
  • Karine Loth, Justine Largillière, Franck Coste, Françoise Culard, Celine Landon, et al.. New protein-DNA complexes in archaea: a small monomeric protein induces a sharp V-turn DNA structure.. EuroMar 2018, Jul 2018, Nantes, France. ⟨hal-02362581⟩
  • H. Meudal, Laurence Jouvensal, K. Loth, Françoise Paquet, V. Aucagne, et al.. Chemical synthesis and natural abundance NMR: An efficient tandem to unravel 3D structures of Disulfide Rich Miniproteins. 35th European Peptide Symposium, Aug 2018, Dublin, Ireland. ⟨hal-02920483⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Celine Landon, A.F. Delmas, et al.. First kinetics description of the EcHU chain exchange system.. 28th ICMRBS - International Council on Magnetic Resonance in Biological Systems, Aug 2018, Dublin, Ireland. ⟨hal-02362586⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system.. 31e colloque Biotechnocentre, Oct 2018, Seillac, France. ⟨hal-02362818⟩
  • Françoise Paquet, H. Meudal, Laurence Jouvensal, K. Loth, V. Aucagne, et al.. Synthèse chimique et RMN en abondance naturelle : un tandem efficace pour résoudre les structures 3D de peptides/protéines riches en ponts disulfure. 5es journées annuelles du GDR MuFoPAM, Oct 2018, Paris, France. ⟨hal-02920025⟩
  • Karine Loth, Françoise Culard, Justine Largillière, Celine Landon, Bertrand Castaing, et al.. New protein-DNA complexes in archaea: a monomeric protein induces a U-turn structure.. 5e séminaire scientifique du LIA MiR-TANGo, May 2018, Orléans, France. ⟨hal-02362804⟩
  • Justine Largillière, Rémy Le Meur, Martine Cadene, Bertrand Castaing, Karine Loth, et al.. Premières études cinétiques du mécanisme d’échange de chaînes de la protéine HU d’Escherischia coli.. Journée Fédération de recherche “Physique et Chimie du Vivant”, Jan 2018, Orléans, France. ⟨hal-02362577⟩
  • Justine Largillière, Rémy Le Meur, Martine Cadene, Bertrand Castaing, Karine Loth, et al.. Premières études cinétiques du mécanisme d’échange de chaînes de la protéine HU d’Escherischia coli.. 16e colloque scientifique de l’ADOC : Converger pour Renforcer, Apr 2018, Orléans, France. ⟨hal-02362579⟩
  • Karine Loth, Justine Largillière, Franck Coste, Françoise Culard, Bertrand Castaing, et al.. New protein-DNA complexes in archaea: a small monomeric protein induces a V-turn structure.. 28th ICMRBS - International Council on Magnetic Resonance in Biological Systems, Aug 2018, Dublin, Ireland. ⟨hal-02362584⟩
  • A.F. Delmas, K. Loth, Herve Meudal, V.P. Terrier, R.D. Rosa, et al.. NCL-based synthesis, 3D structure and first insight into antimicrobial properties of Cg-BigDef1, an oyster big defensin active at high salinity. 20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France. ⟨hal-02894301⟩
  • Justine Largillière, Rémy Le Meur, Martine Cadene, Bertrand Castaing, Karine Loth, et al.. Première description cinétique du mécanisme d’échange de chaînes de la protéine HU d'Escherichia coli.. 30e colloque Biotechnocentre, Oct 2017, Seillac, France. ⟨hal-02361632⟩
  • Karine Loth, Françoise Culard, Justine Largillière, Celine Landon, Bertrand Castaing, et al.. The MC1-DNA complex solution structure reveals that a monomeric protein can induce a U-turn in archaea.. NMR: a tool for biology XTh, Jan 2017, Paris, France. ⟨hal-02361613⟩
  • A. Delmas, K. Loth, Herve Meudal, V. Terrier, R.D. Rosa, et al.. NCL-based synthesis, 3D structure and first insight into antimicrobial properties of Cg-BigDef1, an oyster big defensin active at high salinity. NMR: a tool for Biology Xth, Jan 2017, Paris, France. ⟨hal-02453460⟩
  • Karine Loth, Justine Largillière, Franck Coste, A.F. Delmas, Bertrand Castaing, et al.. New protein-DNA complexes in archaea: a monomeric protein induces a U-turn structure.. Le Studium Confenrence: Structural biology and biophysics of RNA-protein complexes, Nov 2017, Orléans, France. ⟨hal-02362576⟩
  • H. Meudal, Marylène Bertrand, Laurence Jouvensal, A.F. Delmas, Françoise Paquet, et al.. La résonance Magnétique Nucléaire pour la chimie et la biologie. 29e colloque Biotechnocentre, Oct 2016, Seillac, France. ⟨hal-02920143⟩
  • Karine Loth, Denis Costechareyre, Yvan Rahbé, Guy Condemine, Pedro da Silva, et al.. 3D NMR structure of a new Cyt-like delta-endotoxins from Dickeya dadantii. 26. International Conference on Magnetic Resonance in Biological Systems, Aug 2014, Dallas, United States. 1 p., 2014. ⟨hal-02795661⟩

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