MIDOUX Patrick

 

email : patrick.midoux@cnrs-orleans.fr

Phone : +33 2.38.25.55.65

Office  D129

Research director, co-responsible of the thematic group “Innovative therapies and nanomedecine

 



100 documents

Article dans une revue

  • Jean-Pierre Gomez, Guillaume Tresset, Chantal Pichon, Patrick Midoux. Improved histidinylated lPEI polyplexes for skeletal muscle cells transfection. International Journal of Pharmaceutics, Elsevier, 2019, 559, pp.58-67. ⟨10.1016/j.ijpharm.2019.01.003⟩. ⟨hal-02067297⟩
  • Kevin Van Der Jeught, Stefaan de Koker, Lukasz Bialkowski, Carlo Heirman, Patrick Tjok Joe, et al.. Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety. ACS Nano, American Chemical Society, 2018, 12 (10), pp.9815-9829. ⟨https://pubs.acs.org/doi/10.1021/acsnano.8b00966⟩. ⟨10.1021/acsnano.8b00966⟩. ⟨hal-01889829⟩
  • Mathilde Dréan, Antoine Debuigne, Christine Jérôme, Cristine Gonçalves, Patrick Midoux, et al.. Poly( N -methylvinylamine)-Based Copolymers for Improved Gene Transfection. Macromolecular Bioscience, Wiley-VCH Verlag, 2018, 18 (4), pp.1700353. ⟨hal-01966107⟩
  • A. Le Moignic, V. Malard, T. Benvegnu, L. Lemiègre, Mathieu Berchel, et al.. Preclinical evaluation of mRNA trimannosylated lipopolyplexes as therapeutic cancer vaccines targeting dendritic cells. Journal of Controlled Release, Elsevier, 2018, 278, pp.110 - 121. ⟨https://www.sciencedirect.com/science/article/pii/S0168365918301743?via%3Dihub⟩. ⟨10.1016/j.jconrel.2018.03.035⟩. ⟨hal-01774851⟩
  • Cristine Gonçalves, Pierre Gomez, William Même, Bazoly Rasolonjatovo, David Gosset, et al.. Curcumin/poly(2-methyl-2-oxazoline-b-tetrahydrofuran-b-2-methyl-2-oxazoline) formulation: An improved penetration and biological effect of curcumin in F508del-CFTR cell lines. European Journal of Pharmaceutics and Biopharmaceutics, Elsevier, 2017, 117, pp.168-181. ⟨10.1016/j.ejpb.2017.04.015⟩. ⟨hal-01618274⟩
  • Sarwar Beg, Mahfoozur Rahman, Atul Jain, Sumant Saini, Patrick Midoux, et al.. Nanoporous metal organic frameworks as hybrid polymer–metal composites for drug delivery and biomedical applications. Drug Discovery Today Biosilico, Elsevier, 2017, 22 (4), pp.625-637. ⟨10.1016/j.drudis.2016.10.001⟩. ⟨hal-02068701⟩
  • Javed Ahmad, Sohail Akhter, Md. Rizwanullah, Mohammad Ahmed Khan, Lucie Pigeon, et al.. Nanotechnology Based Theranostic Approaches in Alzheimer's Disease Management: Current Status and Future Perspective. Current Alzheimer Research, Bentham Science Publishers, 2017, 14 (11), ⟨10.2174/1567205014666170508121031⟩. ⟨hal-02068674⟩
  • Javed Ahmad, Madhur Singhal, Saima Amin, Md. Rizwanullah, Sohail Akhter, et al.. Bile Salt Stabilized Vesicles (Bilosomes): A Novel Nano-Pharmaceutical Design for Oral Delivery of Proteins and Peptides. Current Pharmaceutical Design, Bentham Science Publishers, 2017, 23 (11), pp.1575 - 1588. ⟨10.2174/1381612823666170124111142⟩. ⟨hal-01656515⟩
  • Thomas Thibault, Jéril Degrouard, Patrick Baril, Chantal Pichon, Patrick Midoux, et al.. Production of DNA minicircles less than 250 base pairs through a novel concentrated DNA circularization assay enabling minicircle design with NF-κB inhibition activity. Nucleic Acids Research, Oxford University Press, 2017, 45 (5), pp.e26 - e26. ⟨10.1093/nar/gkw1034⟩. ⟨hal-01618796⟩
  • Anthony Delalande, Colette Bastié, Lucie Pigeon, Simona Manta, Matthias Lebertre, et al.. Cationic gas-filled microbubbles for ultrasound-based nucleic acids delivery. Bioscience Reports, Portland Press, 2017, 37 (6), pp.BSR20160619. ⟨10.1042/BSR20160619⟩. ⟨hal-02123147⟩
  • Patrick Midoux, Lucie Pigeon, Cristine Goncalves, Chantal Pichon. Peptides mediating DNA transport on microtubules and their impact on non-viral gene transfer efficiency. Bioscience Reports, Portland Press, 2017, 37 (5), pp.BSR20170995. ⟨10.1042/BSR20170995⟩. ⟨hal-02068759⟩
  • Jean-Pierre Gomez, Cristine Gonçalves, Chantal Pichon, Patrick Midoux. Effect of IL-1β, TNF-α and IGF-1 on trans-endothelial passage of synthetic vectors through an in vitro vascular endothelial barrier of striated muscle. Gene Therapy, Nature Publishing Group, 2017, 24 (7), pp.416 - 424. ⟨10.1038/gt.2017.40⟩. ⟨hal-01618260⟩
  • Simona Manta, Gilles Renault, Anthony Delalande, Olivier Couture, Isabelle Lagoutte, et al.. Cationic microbubbles and antibiotic-free miniplasmid for sustained ultrasound–mediated transgene expression in liver. Journal of Controlled Release, Elsevier, 2017, 262, pp.170 - 181. ⟨10.1016/j.jconrel.2017.07.015⟩. ⟨hal-01656574⟩
  • Mathieu Berchel, Sohail Akhter, Wilfried Berthe, Cristine Gonçalvez, Marine Dubuisson, et al.. Synthesis of α-amino-lipophosphonates as cationic lipids or co-lipids for DNA transfection in dendritic cells. Journal of materials chemistry‎ B, Royal Society of Chemistry, 2017, J. Mater. Chem. B, pp.6869-6881 ⟨http://pubs.rsc.org/en/Content/ArticleLanding/2017/TB/C7TB01080J#!divAbstract⟩. ⟨10.1039/C7TB01080J⟩. ⟨hal-01551638⟩
  • Thomas Démoulins, Panagiota Milona, Pavlos C. Englezou, Thomas Ebensen, Kai Schulze, et al.. Polyethylenimine-based polyplex delivery of self-replicating RNA vaccines. Nanomedicine: Nanotechnology, Biology and Medicine, Elsevier, 2016, 12 (3), pp.711 - 722. ⟨10.1016/j.nano.2015.11.001⟩. ⟨hal-01406947⟩
  • L. Pigeon, C. GonÇalves, C. Pichon, P. Midoux. Evidence for plasmid DNA exchange after polyplex mixing. Soft Matter, Royal Society of Chemistry, 2016, 12 (33), pp.7012-7019. ⟨10.1039/c6sm00575f⟩. ⟨hal-02069106⟩
  • Els Verhoeyen, Sophie Gomez, Anne Galy, Eduard Ayuso, Patrick Midoux, et al.. Twelfth Annual Meeting of the French Society of Cell and Gene Therapy. Human Gene Therapy, Mary Ann Liebert, 2016, 27 (7), pp.555-558. ⟨10.1089/hum.2016.29031.eve⟩. ⟨hal-01469045⟩
  • Georges Vassaux, Assia Angelova, Patrick Baril, Patrick Midoux, Jean Rommelaere, et al.. The Promise of Gene Therapy for Pancreatic Cancer. Human Gene Therapy, Mary Ann Liebert, 2016, 27 (2), pp.127 - 133. ⟨10.1089/hum.2015.141⟩. ⟨hal-01407834⟩
  • Cristine Goncalves, Sohail Akhter, Chantal Pichon, Patrick Midoux. Intracellular Availability of pDNA and mRNA after Transfection: A Comparative Study among Polyplexes, Lipoplexes, and Lipopolyplexes. Molecular Pharmaceutics, American Chemical Society, 2016, 13 (9), pp.3153-3163. ⟨10.1021/acs.molpharmaceut.6b00376⟩. ⟨hal-02069071⟩
  • Javed Ahmad, Sohail Akhter, Mohammad Ahmed Khan, Muhammad Wahajuddin, Nigel H. Greig, et al.. Engineered Nanoparticles Against MDR in Cancer: The State of the Art and its Prospective. Current Pharmaceutical Design, Bentham Science Publishers, 2016, 22 (28), pp.4360-4373. ⟨10.2174/1381612822666160617112111⟩. ⟨hal-02068807⟩
  • Mathilde Dréan, Antoine Debuigne, Cristine Gonçalves, Christine Jérôme, Patrick Midoux, et al.. Use of Primary and Secondary Polyvinylamines for Efficient Gene Transfection. Biomacromolecules, American Chemical Society, 2016, 18 (2), pp.440-451. ⟨10.1021/acs.biomac.6b01526⟩. ⟨hal-01427315⟩
  • Mathieu Berchel, Olivier Lozach, Wilfried Berthe, Sylvie Hernot, Hélène Couthon, et al.. Synthetic phospholipids and phospho-bola-amphiphiles for nucleic acid delivery. Phosphorus, Sulfur, and Silicon and the Related Elements, Taylor & Francis, 2016, 191 (11-12), pp.1485 - 1487. ⟨http://www.tandfonline.com/doi/full/10.1080/10426507.2016.1212049?scroll=top&needAccess=true⟩. ⟨10.1080/10426507.2016.1212049⟩. ⟨hal-01539538⟩
  • J. Barbeau, L. Lemiègre, A. Quelen, V. Malard, H. Gao, et al.. Synthesis of a trimannosylated-equipped archaeal diether lipid for the development of novel glycoliposomes. Carbohydrate Research, Elsevier, 2016, 435, pp.142--148. ⟨10.1016/j.carres.2016.10.003⟩. ⟨hal-01398046⟩
  • Magdalena Wytrwal, Chloe Leduc, Michal Sarna, Cristine Goncalves, Mariusz Kepczynski, et al.. Gene delivery efficiency and intracellular trafficking of novel poly(allylamine) derivatives. International Journal of Pharmaceutics, Elsevier, 2015, 478 (1), pp.372-382. ⟨10.1016/j.ijpharm.2014.11.053⟩. ⟨hal-01172009⟩
  • Anthony Delalande, Marie-Pierre Gosselin, Arnaud Suwalski, William Guilmain, Chloé Leduc, et al.. Enhanced Achilles tendon healing by fibromodulin gene transfer. Nanomedicine: Nanotechnology, Biology and Medicine, Elsevier, 2015, 11 (7), pp.1735 - 1744. ⟨http://www.nanomedjournal.com/article/S1549-9634%2815%2900119-7/abstract⟩. ⟨10.1016/j.nano.2015.05.004⟩. ⟨hal-01537597⟩
  • Patrick Midoux, Chantal Pichon. Lipid-based mRNA vaccine delivery systems. Expert Review of Vaccines, Expert Reviews (formerly Future Drugs), 2015, 14 (2), pp.221-234. ⟨10.1586/14760584.2015.986104⟩. ⟨hal-01171750⟩
  • Anthony Delalande, Chloe Leduc, Patrick Midoux, Michiel Postema, Chantal Pichon. Efficient Gene Delivery by Sonoporation Is Associated with Microbubble Entry into Cells and the Clathrin-Dependent Endocytosis Pathway. Ultrasound in Medicine and Biology, Elsevier, 2015, 41 (7), pp.1913-1926. ⟨10.1016/j.ultrasmedbio.2015.03.010⟩. ⟨hal-02072234⟩
  • Bazoly Rasolonjatovo, Jean-Pierre Gomez, William Même, Cristine Gonçalves, Cécile Huin, et al.. Poly(2-methyl-2-oxazoline)-b-poly(tetrahydrofuran)-b-poly(2-methyl-2-oxazoline) Amphiphilic Triblock Copolymers: Synthesis, Physicochemical Characterizations, and Hydrosolubilizing Properties. Biomacromolecules, American Chemical Society, 2015, 16 (3), pp.748-756. ⟨10.1021/bm5016656⟩. ⟨hal-01171865⟩
  • Nawal Belmadi, Patrick Midoux, Pascal Loyer, Catherine Passirani, Chantal Pichon, et al.. Synthetic vectors for gene delivery: An overview of their evolution depending on routes of administration. Biotechnology Journal, Wiley-VCH Verlag, 2015, 10 (9), pp.1370-1389. ⟨10.1002/biot.201400841⟩. ⟨hal-01162373⟩
  • David Brevet, Ouahiba Hocine, Anthony Delalande, Laurence Raehm, Clarence Charnay, et al.. Improved gene transfer with histidine-​functionalized mesoporous silica nanoparticles. International Journal of Pharmaceutics, Elsevier, 2014, pp.197-205. ⟨10.1016/j.ijpharm.2014.05.020⟩. ⟨hal-01068026⟩
  • Cristine Gonçalves, Mathieu Berchel, Marie-Pierre Gosselin, Virginie Malard, Hervé Cheradame, et al.. Lipopolyplexes comprising imidazole/imidazolium lipophosphoramidate, histidinylated polyethyleneimine and siRNA as efficient formulation for siRNA transfection. International Journal of Pharmaceutics, Elsevier, 2014, 460 (1-2), pp.264-272. ⟨10.1016/j.ijpharm.2013.11.005⟩. ⟨hal-01179049⟩
  • Jana Kasparkova, Thomas Thibault, Hana Kostrhunova, Jana Stepankova, Marie Vojtiskova, et al.. Different affinity of nuclear factor-kappa B proteins to DNA modified by antitumor cisplatin and its clinically ineffective trans isomer. FEBS Journal, Wiley, 2014, 281 (5), pp.:1393-1408. ⟨10.1111/febs.12711⟩. ⟨hal-01179156⟩
  • Benoit Maury, Cristine Gonçalves, Guillaume Tresset, Mehdi Zeghal, Hervé Cheradame, et al.. Influence of pDNA availability on transfection efficiency of polyplexes in non-proliferative cells.. Biomaterials, Elsevier, 2014, 35 (22), pp.5977-5985. ⟨10.1016/j.biomaterials.2014.04.007⟩. ⟨hal-01179393⟩
  • Tristan Montier, Chantal Pichon, Marc Blondel, Patrick Midoux. Editorial: Current status and prospects on nucleic acid transfer. Biotechnology Journal, Wiley-VCH Verlag, 2014, 9 (11), pp.1363-1364. ⟨10.1002/biot.201300510⟩. ⟨hal-02135170⟩
  • Cristine Gonçalves, Fabian Gross, Philippe Guégan, Hervé Cheradame, Patrick Midoux. A robust transfection reagent for the transfection of CHO and HEK293 cells and production of recombinant proteins and lentiviral particles - PTG1. Biotechnology Journal, Wiley-VCH Verlag, 2014, 9 (11), pp.1380-1388. ⟨10.1002/biot.201400324⟩. ⟨hal-01179065⟩
  • S Mahindhoratep, H Ait Bouda, Nelly El Shafey, D Scherman, A Kichler, et al.. NF-kB related transgene expression in mouse tibial cranial muscle after pDNA injection followed or not by electrotransfer.. BBA - Biochimica et Biophysica Acta, Elsevier, 2014, 1840 (11), pp.3257-3263. ⟨hal-01179311⟩
  • Ulysse Asseline, Cristine Gonçalves, Chantal Pichon, Patrick Midoux. Improved nuclear delivery of antisense 2′-Ome RNA by conjugation with the histidine-rich peptide H5WYG. The Journal of Gene Medicine, Wiley, 2014, 16 (7-8), pp.157-165. ⟨10.1002/jgm.2773⟩. ⟨hal-01175483⟩
  • Alice Dubois, Patrick Midoux, Delphine Gras, Mustapha Si-Tahar, Deborah Brea, et al.. Poly- l -Lysine Compacts DNA, Kills Bacteria, and Improves Protease Inhibition in Cystic Fibrosis Sputum. American Journal of Respiratory and Critical Care Medicine, American Thoracic Society, 2013, 188 (6), pp.703-709. ⟨10.1164/rccm.201305-0912OC⟩. ⟨hal-02070798⟩
  • Lucie Pigeon, Cristine Gonçalves, David Gosset, Chantal Pichon, Patrick Midoux. An E3-14.7K Peptide that Promotes Microtubules-Mediated Transport of Plasmid DNA Increases Polyplexes Transfection Efficiency.. Small, Wiley-VCH Verlag, 2013, 9 (22), pp.3845-3851. ⟨10.1002/smll.201300217⟩. ⟨hal-00840172⟩
  • Solenne Bire, David Gosset, Gwenhael Jegot, Patrick Midoux, Chantal Pichon, et al.. Exogenous mRNA delivery and bioavailability in gene transfer mediated by piggyBac transposition. BMC Biotechnology, BioMed Central, 2013, 13, pp.1-15. ⟨10.1186/1472-6750-13-75⟩. ⟨hal-01129780⟩
  • Safia Ezzine, Georges Vassaux, Bruno Pitard, Benoit Barteau, Jean-Marc Malinge, et al.. RILES, a novel method for temporal analysis of the in vivo regulation of miRNA expression.. Nucleic Acids Research, Oxford University Press, 2013, epub ahead of print. ⟨10.1093/nar/gkt797⟩. ⟨hal-00874881⟩
  • Anthony Delalande, Spiros Kotopoulis, Michiel Postema, Patrick Midoux, Chantal Pichon. Sonoporation: Mechanistic insights and ongoing challenges for gene transfer. Gene, Elsevier, 2013, 525 (2), pp.191-199. ⟨10.1016/j.gene.2013.03.095⟩. ⟨hal-02070788⟩
  • Jean-Pierre Gomez, Chantal Pichon, Patrick Midoux. Ability of plasmid DNA complexed with histidinylated lPEI and lPEI to cross in vitro lung and muscle vascular endothelial barriers. Gene, Elsevier, 2013, 525 (2), pp.182-190. ⟨10.1016/j.gene.2013.03.055⟩. ⟨hal-02070843⟩
  • Yuliya Sedletska, Françoise Culard, Patrick Midoux, Jean-Marc Malinge. Interaction studies of muts and mutl with DNA containing the major cisplatin lesion and its mismatched counterpart under equilibrium and nonequilibrium conditions.. Biopolymers, Wiley, 2013, 99 (9), pp.636-47. ⟨10.1002/bip.22232⟩. ⟨hal-00874890⟩
  • Mathieu Berchel, Stéphanie Le Corre, Tony Le Gall, Hélène Couthon, Jean-Pierre Haelters, et al.. Trimethylarsonium-Based Cationic Phospholipids for Gene Delivery. Phosphorus, Sulfur, and Silicon and the Related Elements, Taylor & Francis, 2013, 188 (1-3), pp.91-94. ⟨10.1080/10426507.2012.741161⟩. ⟨hal-02070718⟩
  • Federico Perche, Olivier Lambert, Mathieu Berchel, Paul-Alain Jaffres, Chantal Pichon, et al.. Gene transfer by histidylated lipopolyplexes: A dehydration method allowing preservation of their physicochemical parameters and transfection efficiency.. International Journal of Pharmaceutics, Elsevier, 2012, 423 (1), pp.144-50. ⟨10.1016/j.ijpharm.2011.04.009⟩. ⟨hal-00726238⟩
  • Anthony Delalande, Michiel Postema, Nathalie Mignet, Patrick Midoux, Chantal Pichon. Ultrasound and microbubble-assisted gene delivery: recent advances and ongoing challenges.. Ther Deliv, 2012, 3 (10), pp.1199-1215. ⟨hal-00817350⟩
  • Mathieu Berchel, Tony Le Gall, Hélène Couthon, Jean-Pierre Haelters, Tristan Montier, et al.. Lipophosphonate/lipophosphoramidates: a family of synthetic vectors efficient for gene delivery.. Biochimie, Elsevier, 2012, 94 (1), pp.33-41. ⟨10.1016/j.biochi.2011.07.026⟩. ⟨hal-00721772⟩
  • Ludivine Billiet, Jean-Pierre Gomez, Mathieu Berchel, Paul-Alain Jaffres, Tony Le Gall, et al.. Gene transfer by chemical vectors, and endocytosis routes of polyplexes, lipoplexes and lipopolyplexes in a myoblast cell line.. Biomaterials, Elsevier, 2012, 33 (10), pp.2980-90. ⟨10.1016/j.biomaterials.2011.12.027⟩. ⟨hal-00721795⟩
  • Federico Perche, Thierry Benvegnu, Mathieu Berchel, Loic Lebegue, Chantal Pichon, et al.. Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA.. Nanomedicine: Nanotechnology, Biology and Medicine, Elsevier, 2011, 7 (4), pp.445-53. ⟨10.1016/j.nano.2010.12.010⟩. ⟨hal-00754373⟩
  • Mathieu Berchel, Jean-Piere Haelters, Hélène Couthon, Laure Deschamps, Patrick Midoux, et al.. Modular Construction of Fluorescent Lipophosphoramidates by Click Chemistry. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2011, pp.6294-6303. ⟨10.1002/ejoc.201100900⟩. ⟨hal-00720537⟩
  • Véronique Bennevault-Celton, Allan Urbach, Olivier Martin, Chantal Pichon, Philippe Guégan, et al.. Supramolecular assemblies of histidinylated α-cyclodextrin in the presence of DNA scaffold during CDplexes formation.. Bioconjugate Chemistry, American Chemical Society, 2011, 22 (12), pp.2404-14. ⟨10.1021/bc200167p⟩. ⟨hal-00720527⟩
  • Paul-Alain Jaffres, Aurore Fraix, Christophe Lorilleux, Mathieu Berchel, Hélène Couthon, et al.. New Lipo-Phosphoramidates for Gene Delivery. Phosphorus, Sulfur, and Silicon and the Related Elements, Taylor & Francis, 2011, 186 (4), pp.918-920. ⟨10.1080/10426507.2010.522639⟩. ⟨hal-00614938⟩
  • Federico Perche, David Gosset, Mathieu Mével, Marie-Laure Miramon, Jean-Jacques Yaouanc, et al.. Selective gene delivery in dendritic cells with mannosylated and histidylated lipopolyplexes.. Journal of Drug Targeting, Informa Healthcare, 2011, 19 (5), pp.315-25. ⟨10.3109/1061186X.2010.504262⟩. ⟨hal-00753554⟩
  • Anthony Delalande, Ayache Bouakaz, Gilles Renault, Flore Tabareau, Spiros Kotopoulis, et al.. Ultrasound and microbubble-assisted gene delivery in Achilles tendons: long lasting gene expression and restoration of fibromodulin KO phenotype.. Journal of Controlled Release, Elsevier, 2011, 156 (2), pp.223-30. ⟨10.1016/j.jconrel.2011.08.020⟩. ⟨hal-00720602⟩
  • Emilie Bertrand, Cristine Gonçalves, Ludivine Billiet, Jean Pierre Gomez, Chantal Pichon, et al.. Histidinylated linear PEI: a new efficient non-toxic polymer for gene transfer.. Chemical Communications, Royal Society of Chemistry, 2011, 47 (46), pp.12547-9. ⟨10.1039/c1cc15716g⟩. ⟨hal-00720539⟩
  • Anthony Delalande, Michel-Francis Bureau, Patrick Midoux, Ayache Bouakaz, Chantal Pichon. Ultrasound-assisted microbubbles gene transfer in tendons for gene therapy. Ultrasonics Sonochemistry, Elsevier, 2010, 50 (2), pp.269-272. ⟨10.1016/j.ultras.2009.09.035⟩. ⟨hal-00529321⟩
  • K. Kaddur, L. Lebegue, F. Tranquart, P. Midoux, C. Pichon, et al.. Transient transmembrane release of green fluorescent proteins with sonoporation. IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, Institute of Electrical and Electronics Engineers, 2010, 57 (7), pp.1558-1567. ⟨10.1109/TUFFC.2010.1586⟩. ⟨hal-00529340⟩
  • Matthieu Fisichella, Hinda Dabboue, Sanjib Bhattacharyya, Gerald Lelong, Marie-Louise Saboungi, et al.. Uptake of Functionalized Mesoporous Silica Nanoparticles by Human Cancer Cells. Journal of Nanoscience and Nanotechnology, American Scientific Publishers, 2010, 10 (4), pp.314-2324. ⟨10.1166/jnn.2010.1917⟩. ⟨hal-00529333⟩
  • Chantal Pichon, Ludivine Billiet, Patrick Midoux. Chemical vectors for gene delivery: uptake and intracellular trafficking. Current Opinion in Biotechnology, Elsevier, 2010, 21 (5), pp.640-645. ⟨10.1016/j.copbio.2010.07.003⟩. ⟨hal-00602488⟩
  • Arnaud Suwalski, Hinda Dabboue, Anthony Delalande, Sabine F. Bensamoun, Francis Canon, et al.. Accelerated Achilles tendon healing by PDGF gene delivery with mesoporous silica nanoparticles. Biomaterials, Elsevier, 2010, 31 (19), pp.5237-5245. ⟨10.1016/j.biomaterials.2010.02.077⟩. ⟨hal-00529475⟩
  • Marie Breton, Jeanne Leblond, Johanne Seguin, Patrick Midoux, Daniel Scherman, et al.. Comparative gene transfer between cationic and thiourea lipoplexes. The Journal of Gene Medicine, Wiley, 2010, 12 (1), pp.45-54. ⟨10.1002/jgm.1417⟩. ⟨hal-00529308⟩
  • Corinne Bure, Régine Maget, Agnès F. Delmas, Chantal Pichon, Patrick Midoux. Histidine-rich peptide: evidence for a single zinc-binding site on H5WYG peptide that promotes membrane fusion at neutral pH. Journal of Mass Spectrometry, Wiley-Blackwell, 2009, 44 (1), pp.81-89. ⟨10.1002/jms.1473⟩. ⟨hal-00521834⟩
  • Corinne Bure, Chantal Pichon, Patrick Midoux. Involvement of histidines 11, 15 and 19 in the binding of zinc to the fusogenic H5WYG peptide. Journal of Mass Spectrometry, Wiley-Blackwell, 2009, 44 (8), pp.1163-1170. ⟨10.1002/jms.1591⟩. ⟨hal-00521851⟩
  • Patrick Midoux, Chantal Pichon, Jean-Jacques Yaouanc, Paul-Alain Jaffres. Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers. British Journal of Pharmacology, Wiley, 2009, 157 (2), pp.166-178. ⟨10.1111/j.1476-5381.2009.00288.x⟩. ⟨hal-00525108⟩
  • Cristine Gonçalves, Marie-Yvonne Ardourel, Martine Decoville, Gilles Breuzard, Patrick Midoux, et al.. An optimized extended DNA kappa B site that enhances plasmid DNA nuclear import and gene expression. The Journal of Gene Medicine, Wiley, 2009, 11 (5), pp.401-411. ⟨10.1002/jgm.1312⟩. ⟨hal-00522437⟩
  • Kadija Kaddur, Anthony Delalande, François Tranquart, Patrick Midoux, Chantal Pichon, et al.. Extraction of green fluorescent proteins with sonoporation. Journal of the Acoustical Society of America, Acoustical Society of America, 2008, 123 (5), pp.3218-3218. ⟨10.1121/1.2933412⟩. ⟨hal-02128161⟩
  • Valerie Boutin, Alain Legrand, Roger Mayer, Maurice Nachtigal, Michel Monsigny, et al.. Glycofection: The Ubiquitous Roles of Sugar Bound on Glycoplexes. Drug Delivery, Taylor & Francis, 2008, 6 (1), pp.45-50. ⟨10.1080/107175499267156⟩. ⟨hal-02138035⟩
  • Patrick Midoux, Gilles Breuzard, Jean-Pierre Gomez, Chantal Pichon. Polymer-Based Gene Delivery: A Current Review on the Uptake and Intracellular Trafficking of Polyplexes. Current Gene Therapy, Bentham Science Publishers, 2008, 8 (5), pp.335-352. ⟨hal-00518197⟩
  • Gilles Breuzard, Magdalena Tertil, Cristine Gonçalves, Hervé Cheradame, Philippe Géguan, et al.. Nuclear delivery of NFkappaB-assisted DNA/polymer complexes: plasmid DNA quantitation by confocal laser scanning microscopy and evidence of nuclear polyplexes by FRET imaging.. Nucleic Acids Research, Oxford University Press, 2008, 36 (12), pp.e71. ⟨10.1093/nar/gkn287⟩. ⟨hal-00408004⟩
  • Mathieu Mével, Jean-Jacques Yaouanc, Pascal Laurent, Claude Clément, Dominique Cartier, et al.. Cationic Lipids Based on Phosphonate and Phosphoramidate Chemistry: Synthesis and Application to Gene Therapy. Phosphorus, Sulfur, and Silicon and the Related Elements, Taylor & Francis, 2008, 183 (2-3), pp.460 - 468. ⟨10.1080/10426500701761300⟩. ⟨hal-01580434⟩
  • Chantal Pichon, Kadija Kaddur, Patrick Midoux, François Tranquart, Ayache Bouakaz. Recent advances in gene delivery with ultrasound and microbubbles. Journal of Experimental Nanoscience, Taylor & Francis, 2008, 3 (1), pp.17-40. ⟨10.1080/17458080801993422⟩. ⟨hal-00518203⟩
  • M. Mevel, Gilles Breuzard, J.-J. Yaouanc, J.-C. Clement, P. Lehn, et al.. Synthesis and transfection activity of new cationic phosphoramidate lipids: High efficiency of an imidazolium derivative. ChemBioChem, Wiley-VCH Verlag, 2008, 9 (9), pp.1462-1471. ⟨10.1002/cbic.200700727⟩. ⟨hal-00518184⟩
  • M. Mevel, C. Neveu, Cristine Goncalves, J.-J. Yaouanc, Chantal Pichon, et al.. Novel neutral imidazole-lipophosphoramides for transfection assays. Chemical Communications, Royal Society of Chemistry, 2008, pp.3124-3126. ⟨10.1039/b805226c⟩. ⟨hal-00518192⟩
  • Gilles Breuzard, M. Tertil, Chantal Pichon, Patrick Midoux. Intracellular trafficking and nuclear import of polyplexes by FRET coupled with cellular imaging. Human Gene Therapy, Mary Ann Liebert, 2007, 18, pp.1048. ⟨hal-00275215⟩
  • M. Mockey, C. Goncalves, F.P. Dupuy, F.M. Lemoine, C. Pichon, et al.. mRNA transfection of dendritic cells: synergistic effect of ARCA mRNA capping with Poly(A) chains in cis and in trans for a high protein expression level. Biochemical and Biophysical Research Communications, Elsevier, 2006, 340, pp.1062-1068. ⟨10.1016/j.bbrc.2005.12.105⟩. ⟨hal-00088921⟩
  • Eric Mennesson, Patrick Erbacher, Mateusz Kuzak, Claudine Kieda, Patrick Midoux, et al.. DNA/cationic polymer complex attachment on a human vascular endothelial cell monolayer exposed to a steady laminar flow. Journal of Controlled Release, Elsevier, 2006, 114 (3), pp.389-397. ⟨10.1016/j.jconrel.2006.06.006⟩. ⟨hal-00112894⟩
  • E. Mennesson, P. Erbacher, V. Piller, C. Kieda, P. Midoux, et al.. Transfection efficiency and uptake process of polyplexes in human lung endothetial cells: a comparative study in non-polarized and polarized cells. The Journal of Gene Medicine, Wiley, 2005, 7, pp.729-738. ⟨hal-00088642⟩
  • A. Kamal, B.A. Kumar, M. Arifuddin, P. Midoux. An efficient and facile nitration of phenols with nitric acid/zinc chloride under ultrasonic conditions. Ultrasonics sonochemistry., 2004, 11, pp.455-457. ⟨hal-00088378⟩
  • T. Montier, P. DelÉpine, C. Pichon, C. Férec, D.J. Porteous, et al.. Non-viral vectors in cystic fibrosis gene therapy: progress and challenges. Trends in biotechnology., 2004, 22, pp.586-592. ⟨hal-00088424⟩
  • R.S. Singh, C. GonÇalves, P. Sandrin, C. Pichon, P. Midoux, et al.. On the gene delivery efficacies of pH-sensitive cationic lipids via endosomal protonation: a chemical biology investigation. Chemistry & biology, 2004, 11, pp.713-723. ⟨hal-00088426⟩
  • Ibrahim Elmadbouh, Patrick Rossignol, Olivier Meilhac, Roger Vranckx, Chantal Pichon, et al.. Optimization of in vitro vascular cell transfection with non-viral vectors for in vivo applications. The Journal of Gene Medicine, Wiley, 2004, 6 (10), pp.1112-1124. ⟨hal-00014241⟩
  • Chantal Pichon, Eric Lecam, Brigitte Guérin, Dominique Coulaud, Etienne Delain, et al.. Poly[Lys-(AEDTP)]: a cationic polymer that allows dissociation of pDNA/cationic polymer complexes in a reductive medium and enhances polyfection.. Bioconjugate Chemistry, American Chemical Society, 2002, 13 (1), pp.76-82. ⟨hal-02135235⟩
  • V Kumar, Chantal Pichon, M. Refregiers, B Guerin, P. Midoux, et al.. Single histidine residue in head-group region is sufficient to impart remarkable gene transfection properties to cationic lipids: evidence for histidine-mediated membrane fusion at acidic pH. Gene Therapy, Nature Publishing Group, 2002, 10 (15), pp.1206 - 1215. ⟨10.1038/sj.gt.3301979⟩. ⟨hal-01596052⟩
  • Christine Gonçalves, Chantal Pichon, Brigitte Guérin, Patrick Midoux. Intracellular processing and stability of DNA complexed with histidylated polylysine conjugates. The Journal of Gene Medicine, Wiley, 2002, 4 (3), pp.271-281. ⟨10.1002/jgm.277⟩. ⟨hal-02135970⟩
  • Chantal Pichon, Brigitte Guérin, Matthieu Refregiers, Christine Gonçalves, Paul Vigny, et al.. Zinc improves gene transfer mediated by DNA/cationic polymer complexes. The Journal of Gene Medicine, Wiley, 2002, 4 (5), pp.548 - 559. ⟨10.1002/jgm.303⟩. ⟨hal-01596013⟩
  • Chantal Pichon, C Gonçalves, P. Midoux. Histidine-rich peptides and polymers for nucleic acids delivery.. Advanced Drug Delivery Reviews, Elsevier, 2001, 53 (1), pp.75-94. ⟨hal-02135973⟩
  • Chantal Pichon, Mahajoub Bello Roufaï, Michel Monsigny, Patrick Midoux. Histidylated oligolysines increase the transmembrane passage and the biological activity of antisense oligonucleotides. Nucleic Acids Research, Oxford University Press, 2000, 28 (2), pp.504-512. ⟨10.1093/nar/28.2.504⟩. ⟨hal-02135979⟩
  • Isabelle Fajac, J.C Allo, Evelyne Souil, Marc Merten, Chantal Pichon, et al.. Histidylated polylysine as a synthetic vector for gene transfer into immortalized cystic fibrosis airway surface and airway gland serous cells. The Journal of Gene Medicine, Wiley, 2000, 2 (5), pp.368-378. 3.0.CO;2-F">⟨10.1002/1521-2254(200009/10)2:5<368::AID-JGM118>3.0.CO;2-F⟩. ⟨hal-02135988⟩
  • M Monsigny, C. Quétard, S. Bourgerie, D. Delay, Chantal Pichon, et al.. Glycotargeting: the preparation of glyco-amino acids and derivatives from unprotected reducing sugars.. Biochimie, Elsevier, 1998, 80 (2), pp.99-108. ⟨hal-02136005⟩
  • Chantal Pichon, Isabelle Freulon, Patrick Midoux, Roger Mayer, Michel Monsigny, et al.. Cytosolic and Nuclear Delivery of Oligonucleotides Mediated by an Amphiphilic Anionic Peptide. Antisense and Nucleic Acid Drug Development, Mary Ann Liebert, 1997, 7 (4), pp.335-343. ⟨10.1089/oli.1.1997.7.335⟩. ⟨hal-02136009⟩
  • A. Stewart, Chantal Pichon, L Meunier, P Midoux, M. Monsigny, et al.. Enhanced biological activity of antisense oligonucleotides complexed with glycosylated poly-L-lysine.. Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 1996, 50 (6), pp.1487-94. ⟨hal-02136015⟩
  • Patrick Midoux, Christina Mendes, Alain Legrand, Jacques Raimond, Roger Mayer, et al.. Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells. Nucleic Acids Research, Oxford University Press, 1993, 21 (4), pp.871-878. ⟨10.1093/nar/21.4.871⟩. ⟨hal-02138456⟩

Communication dans un congrès

  • Simona Manta, Anthony Delalande, Gilles Renault, Michel Francis Bureau, Matthias Lebertre, et al.. Positively charged microbubbles to target nucleic acid delivery with ultrasound. Journées RITS 2015, Mar 2015, Dourdan, France. ⟨inserm-01154976⟩

Chapitre d'ouvrage

  • Chantal Pichon, Patrick Midoux. Mannosylated and Histidylated LPR Technology for Vaccination with Tumor Antigen mRNA. Synthetic Messenger RNA and Cell Metabolism Modulation, pp.247-274, 2013, ⟨10.1007/978-1-62703-260-5_16⟩. ⟨hal-02070913⟩
  • P. Midoux, E. Lecam, D. Coulaud, E. Delain, C. Pichon. Histidine containing peptides and polypeptides as nucleic acid vectors. Luo D., Saltzman W.M. Synthetic DNA Delivery Systems, Kluwer Academic/Plenum Publishers, New-York, pp.23-44, 2003. ⟨hal-00115810⟩
  • P. Midoux, C. Pichon. Peptide-based gene delivery systems. Mahato R.I., Kim S.W. Pharmaceutical perspectives of nucleic acid-based, Taylor & Francis, London and New York, pp.334-366, 2002. ⟨hal-00115804⟩
  • P. Midoux, C. Pichon. Histidylated polycationic molecules for nucleic acids transfer. Pandalai S.G. Recent research developments in bioconjugate chemistry, Transworld Research Network, Trivandrum, pp.95-111, 2002. ⟨hal-00115805⟩
  • M. Monsigny, C. Quétard, E. Duverger, C. Pichon, V. Altemayer, et al.. Glycoconjugates as vectors for gene and oligonucleotide delivery. Aubery M. Glycans in cellular interaction and recognition: therapeutic, Harwood Academic Publishers, Amsterdam, pp.193-215, 2002. ⟨hal-00115807⟩

Brevet

  • Jean-Marc Malinge, Patrick Midoux, Thomas Thibault, Chantal Pichon. In vitro production of DNA minicircles less than 250 base pairs. France, Patent n° : EP2735614A1. 2014. ⟨hal-02134791⟩