MIDOUX Patrick

 

email : patrick.midoux[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.55.65

Emeritus research director within the thematic group Innovative therapies and nanomedicine

 


184 documents

Article dans une revue162 documents

  • Sohail Akhter, Mathieu Berchel, Paul-Alain Jaffrès, Chantal Pichon, Patrick Midoux. mRNA Lipoplexes with Cationic and Ionizable α-Amino-lipophosphonates: Membrane Fusion, Transfection, mRNA Translation and Conformation. Pharmaceutics, 2022, 14 (3), pp.581. ⟨10.3390/pharmaceutics14030581⟩. ⟨hal-03927316⟩
  • Pauline Le Bellec, Patrick Midoux, Hervé Cheradame, Véronique Bennevault, Philippe Guégan. Tuneable thermal properties of PTHF-based copolymers by incorporation of epoxide units. European Polymer Journal, 2022, 168, pp.111096. ⟨10.1016/j.eurpolymj.2022.111096⟩. ⟨hal-03927816⟩
  • Christophe Delehedde, Luc Even, Patrick Midoux, Chantal Pichon, Federico Perche. Intracellular Routing and Recognition of Lipid-Based mRNA Nanoparticles. Pharmaceutics, 2021, 13 (7), pp.945. ⟨10.3390/pharmaceutics13070945⟩. ⟨hal-03335664⟩
  • Viorel Simion, Claire Loussouarn, Yoan Laurent, Loris Roncali, David Gosset, et al.. LentiRILES, a miRNA-ON Sensor System for Monitoring the Functionality of miRNA in Cancer Biology and Therapy. RNA Biology/RNA Biol., 2021, Online ahead of print. ⟨10.1080/15476286.2021.1978202⟩. ⟨inserm-03374619⟩
  • Bazoly Rasolonjatovo, Nicolas Illy, Véronique Bennevault, Jérôme Mathé, Patrick Midoux, et al.. Temperature‐Sensitive Amphiphilic Non‐Ionic Triblock Copolymers for Enhanced In Vivo Skeletal Muscle Transfection. Macromolecular Bioscience, 2020, 20 (3), pp.1900276. ⟨10.1002/mabi.201900276⟩. ⟨hal-02451051⟩
  • Hao Li, Carolina Gascó, Anthony Delalande, Clarence Charnay, Laurence Raehm, et al.. Periodic Mesoporous Organosilica Nanoparticles with BOC Group, towards HIFU Responsive Agents. Molecules, 2020, 25 (4), pp.974. ⟨10.3390/molecules25040974⟩. ⟨hal-02544155⟩
  • Viorel Simion, Elodie Henriet, Viktorija Juric, Ruth Aquino, Claire Loussouarn, et al.. Intracellular trafficking and functional monitoring of miRNA delivery in glioblastoma using lipopolyplexes and the miRNA-ON RILES reporter system. Journal of Controlled Release, 2020, 327, pp.429-443. ⟨10.1016/j.jconrel.2020.08.028⟩. ⟨hal-02959393⟩
  • Laetitia Plet, Gwendoline Delecourt, Mohamed Hanafi, Nadège Pantoustier, Gaelle Pembouong, et al.. Controlled star poly(2-oxazoline)s: Synthesis, characterization. European Polymer Journal, 2020, 122, pp.109323. ⟨10.1016/j.eurpolymj.2019.109323⟩. ⟨hal-02541990⟩
  • Yann Thierry Le Guen, Tony Le Gall, Patrick Midoux, Philippe Guégan, Serge Braun, et al.. Gene transfer to skeletal muscle using hydrodynamic limb vein injection: current applications, hurdles and possible optimizations. The Journal of Gene Medicine, 2020, 22 (2), ⟨10.1002/jgm.3150⟩. ⟨hal-03668402⟩
  • Haifei Gao, Cristine Goncalves, Téo Gallego, Marc Francois-Heude, Virginie Malard, et al.. Comparative binding and uptake of liposomes decorated with mannose oligosaccharides by cells expressing the mannose receptor or DC-SIGN. Carbohydrate Research, 2020, 487, pp.107877. ⟨10.1016/j.carres.2019.107877⟩. ⟨hal-02522179⟩
  • Pinpin Wang, Delphine Logeart-Avramoglou, Hervé Petite, Cristine Gonçalves, Patrick Midoux, et al.. Co-delivery of NS1 and BMP2 mRNAs to murine pluripotent stem cells leads to enhanced BMP-2 expression and osteogenic differentiation. Acta Biomaterialia, 2020, 108, pp.337-346. ⟨10.1016/j.actbio.2020.03.045⟩. ⟨hal-02553030⟩
  • Arnaud Chaix, Eduardo Cueto-Diaz, Anthony Delalande, Nikola Knezevic, Patrick Midoux, et al.. Amino-acid functionalized porous silicon nanoparticles for the delivery of pDNA. RSC Advances, 2019, 9 (55), pp.31895-31899. ⟨10.1039/c9ra05461h⟩. ⟨hal-02338857⟩
  • Jean-Pierre Gomez, Guillaume Tresset, Chantal Pichon, Patrick Midoux. Improved histidinylated lPEI polyplexes for skeletal muscle cells transfection. International Journal of Pharmaceutics, 2019, 559, pp.58-67. ⟨10.1016/j.ijpharm.2019.01.003⟩. ⟨hal-02067297⟩
  • Kevin van Der Jeught, Stefaan de Koker, Lukasz Bialkowski, Carlo Heirman, Patrick Tjok Joe, et al.. Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety. ACS Nano, 2018, 12 (10), pp.9815-9829. ⟨10.1021/acsnano.8b00966⟩. ⟨hal-01889829⟩
  • M. Treyer, K. Kraljic, S. Arnouts, S. de La Torre, C. Pichon, et al.. Group quenching and galactic conformity at low redshift. Monthly Notices of the Royal Astronomical Society, 2018, 477 (2), pp.2684-2704. ⟨10.1093/mnras/sty769⟩. ⟨hal-01876752⟩
  • A. Le Moignic, V. Malard, T. Benvegnu, L. Lemiègre, Mathieu Berchel, et al.. Preclinical evaluation of mRNA trimannosylated lipopolyplexes as therapeutic cancer vaccines targeting dendritic cells. Journal of Controlled Release, 2018, 278, pp.110 - 121. ⟨10.1016/j.jconrel.2018.03.035⟩. ⟨hal-01774851⟩
  • Mathilde Dréan, Antoine Debuigne, Christine Jérôme, Cristine Gonçalves, Patrick Midoux, et al.. Poly( N -methylvinylamine)-based copolymers for improved gene transfection. Macromolecular Bioscience, 2018, 18 (4), pp.1700353. ⟨10.1002/mabi.201700353⟩. ⟨hal-01966107⟩
  • Javed Ahmad, Madhur Singhal, Saima Amin, Md. Rizwanullah, Sohail Akhter, et al.. Bile Salt Stabilized Vesicles (Bilosomes): A Novel Nano-Pharmaceutical Design for Oral Delivery of Proteins and Peptides. Current Pharmaceutical Design, 2017, 23 (11), pp.1575 - 1588. ⟨10.2174/1381612823666170124111142⟩. ⟨hal-01656515⟩
  • Jean-Pierre Gomez, Cristine Gonçalves, Chantal Pichon, Patrick Midoux. Effect of IL-1β, TNF-α and IGF-1 on trans-endothelial passage of synthetic vectors through an in vitro vascular endothelial barrier of striated muscle. Gene Therapy, 2017, 24 (7), pp.416 - 424. ⟨10.1038/gt.2017.40⟩. ⟨hal-01618260⟩
  • Sarwar Beg, Mahfoozur Rahman, Atul Jain, Sumant Saini, Patrick Midoux, et al.. Nanoporous metal organic frameworks as hybrid polymer–metal composites for drug delivery and biomedical applications. Drug Discovery Today Biosilico, 2017, 22 (4), pp.625-637. ⟨10.1016/j.drudis.2016.10.001⟩. ⟨hal-02068701⟩
  • Anthony Delalande, Colette Bastié, Lucie Pigeon, Simona Manta, Matthias Lebertre, et al.. Cationic gas-filled microbubbles for ultrasound-based nucleic acids delivery. Bioscience Reports, 2017, 37 (6), pp.BSR20160619. ⟨10.1042/BSR20160619⟩. ⟨hal-02123147⟩
  • Mathilde Dréan, Antoine Debuigne, Cristine Gonçalves, Christine Jérôme, Patrick Midoux, et al.. Use of Primary and Secondary Polyvinylamines for Efficient Gene Transfection. Biomacromolecules, 2017, 18 (2), pp.440-451. ⟨10.1021/acs.biomac.6b01526⟩. ⟨hal-01427315⟩
  • Javed Ahmad, Sohail Akhter, Md. Rizwanullah, Mohammad Ahmed Khan, Lucie Pigeon, et al.. Nanotechnology Based Theranostic Approaches in Alzheimer's Disease Management: Current Status and Future Perspective. Current Alzheimer Research, 2017, 14 (11), pp.1164-1181. ⟨10.2174/1567205014666170508121031⟩. ⟨hal-02068674⟩
  • Patrick Midoux, Lucie Pigeon, Cristine Goncalves, Chantal Pichon. Peptides mediating DNA transport on microtubules and their impact on non-viral gene transfer efficiency. Bioscience Reports, 2017, 37 (5), pp.BSR20170995. ⟨10.1042/BSR20170995⟩. ⟨hal-02068759⟩
  • Cristine Gonçalves, Pierre Gomez, William Même, Bazoly Rasolonjatovo, David Gosset, et al.. Curcumin/poly(2-methyl-2-oxazoline-b-tetrahydrofuran-b-2-methyl-2-oxazoline) formulation: An improved penetration and biological effect of curcumin in F508del-CFTR cell lines. European Journal of Pharmaceutics and Biopharmaceutics, 2017, 117, pp.168-181. ⟨10.1016/j.ejpb.2017.04.015⟩. ⟨hal-01618274⟩
  • Simona Manta, Gilles Renault, Anthony Delalande, Olivier Couture, Isabelle Lagoutte, et al.. Cationic microbubbles and antibiotic-free miniplasmid for sustained ultrasound–mediated transgene expression in liver. Journal of Controlled Release, 2017, 262, pp.170 - 181. ⟨10.1016/j.jconrel.2017.07.015⟩. ⟨hal-01656574⟩
  • Thomas Thibault, Jéril Degrouard, Patrick Baril, Chantal Pichon, Patrick Midoux, et al.. Production of DNA minicircles less than 250 base pairs through a novel concentrated DNA circularization assay enabling minicircle design with NF-κB inhibition activity. Nucleic Acids Research, 2017, 45 (5), pp.e26 - e26. ⟨10.1093/nar/gkw1034⟩. ⟨hal-01618796⟩
  • Mathieu Berchel, Sohail Akhter, Wilfried Berthe, Cristine Gonçalvez, Marine Dubuisson, et al.. Synthesis of α-amino-lipophosphonates as cationic lipids or co-lipids for DNA transfection in dendritic cells. Journal of materials chemistry‎ B, 2017, J. Mater. Chem. B, 5, pp.6869-6881. ⟨10.1039/C7TB01080J⟩. ⟨hal-01551638⟩
  • Mohammad Zaki Ahmad, Basel Abdel-Wahab, Afroze Alam, Sobiya Zafar, Javed Ahmad, et al.. Toxicity of Inorganic Nanoparticles Used in Targeted Drug Delivery and Other Biomedical Application: An Updated Account on Concern of Biomedical Nanotoxicology. Journal of Nanoscience and Nanotechnology, 2016, 16 (8), pp.7873-7897. ⟨10.1166/jnn.2016.13032⟩. ⟨hal-02519256⟩
  • Javed Ahmad, Sohail Akhter, Mohammad Ahmed Khan, Muhammad Wahajuddin, Nigel H. Greig, et al.. Engineered Nanoparticles Against MDR in Cancer: The State of the Art and its Prospective. Current Pharmaceutical Design, 2016, 22 (28), pp.4360-4373. ⟨10.2174/1381612822666160617112111⟩. ⟨hal-02068807⟩
  • Mathieu Berchel, Olivier Lozach, Wilfried Berthe, Sylvie Hernot, Hélène Couthon, et al.. Synthetic phospholipids and phospho-bola-amphiphiles for nucleic acid delivery. Phosphorus, Sulfur, and Silicon and the Related Elements, 2016, 191 (11-12), pp.1485 - 1487. ⟨10.1080/10426507.2016.1212049⟩. ⟨hal-01539538⟩
  • Thomas Démoulins, Panagiota Milona, Pavlos C. Englezou, Thomas Ebensen, Kai Schulze, et al.. Polyethylenimine-based polyplex delivery of self-replicating RNA vaccines. Nanomedicine: Nanotechnology, Biology and Medicine, 2016, 12 (3), pp.711 - 722. ⟨10.1016/j.nano.2015.11.001⟩. ⟨hal-01406947⟩
  • Georges Vassaux, Assia Angelova, Patrick Baril, Patrick Midoux, Jean Rommelaere, et al.. The promise of gene therapy for pancreatic cancer. Human Gene Therapy, 2016, 27 (2), pp.127 - 133. ⟨10.1089/hum.2015.141⟩. ⟨hal-01407834⟩
  • Cristine Goncalves, Sohail Akhter, Chantal Pichon, Patrick Midoux. Intracellular Availability of pDNA and mRNA after Transfection: A Comparative Study among Polyplexes, Lipoplexes, and Lipopolyplexes. Molecular Pharmaceutics, 2016, 13 (9), pp.3153-3163. ⟨10.1021/acs.molpharmaceut.6b00376⟩. ⟨hal-02069071⟩
  • L. Pigeon, C. Gonçalves, C. Pichon, P. Midoux. Evidence for plasmid DNA exchange after polyplex mixing. Soft Matter, 2016, 12 (33), pp.7012-7019. ⟨10.1039/c6sm00575f⟩. ⟨hal-02069106⟩
  • J. Barbeau, L. Lemiègre, A. Quelen, V. Malard, H. Gao, et al.. Synthesis of a trimannosylated-equipped archaeal diether lipid for the development of novel glycoliposomes. Carbohydrate Research, 2016, 435, pp.142--148. ⟨10.1016/j.carres.2016.10.003⟩. ⟨hal-01398046⟩
  • Els Verhoeyen, Sophie Gomez, Anne Galy, Eduard Ayuso, Patrick Midoux, et al.. Twelfth Annual Meeting of the French Society of Cell and Gene Therapy. Human Gene Therapy, 2016, 27 (7), pp.555-558. ⟨10.1089/hum.2016.29031.eve⟩. ⟨hal-01469045⟩
  • Patrick Midoux, Chantal Pichon. Lipid-based mRNA vaccine delivery systems. Expert Review of Vaccines, 2015, 14 (2), pp.221-234. ⟨10.1586/14760584.2015.986104⟩. ⟨hal-01171750⟩
  • Bazoly Rasolonjatovo, Jean-Pierre Gomez, William Même, Cristine Gonçalves, Cécile Huin, et al.. Poly(2-methyl-2-oxazoline)-b-poly(tetrahydrofuran)-b-poly(2-methyl-2-oxazoline) Amphiphilic Triblock Copolymers: Synthesis, Physicochemical Characterizations, and Hydrosolubilizing Properties. Biomacromolecules, 2015, 16 (3), pp.748-756. ⟨10.1021/bm5016656⟩. ⟨hal-01171865⟩
  • Magdalena Wytrwal, Chloe Leduc, Michal Sarna, Cristine Goncalves, Mariusz Kepczynski, et al.. Gene delivery efficiency and intracellular trafficking of novel poly(allylamine) derivatives. International Journal of Pharmaceutics, 2015, 478 (1), pp.372-382. ⟨10.1016/j.ijpharm.2014.11.053⟩. ⟨hal-01172009⟩
  • Anthony Delalande, Marie-Pierre Gosselin, Arnaud Suwalski, William Guilmain, Chloé Leduc, et al.. Enhanced Achilles tendon healing by fibromodulin gene transfer. Nanomedicine: Nanotechnology, Biology and Medicine, 2015, 11 (7), pp.1735 - 1744. ⟨10.1016/j.nano.2015.05.004⟩. ⟨hal-01537597⟩
  • Anthony Delalande, Chloe Leduc, Patrick Midoux, Michiel Postema, Chantal Pichon. Efficient gene delivery by sonoporation is associated with microbubble entry into cells and the clathrin-dependent endocytosis pathway. Ultrasound in Medicine & Biology, 2015, 41 (7), pp.1913-1926. ⟨10.1016/j.ultrasmedbio.2015.03.010⟩. ⟨hal-03198520⟩
  • Nawal Belmadi, Patrick Midoux, Pascal Loyer, Catherine Passirani, Chantal Pichon, et al.. Synthetic vectors for gene delivery: An overview of their evolution depending on routes of administration. Biotechnology Journal, 2015, 10 (9), pp.1370-1389. ⟨10.1002/biot.201400841⟩. ⟨hal-01162373⟩
  • Tristan Montier, Chantal Pichon, Marc Blondel, Patrick Midoux. Editorial: Current status and prospects on nucleic acid transfer. Biotechnology Journal, 2014, 9 (11), pp.1363-1364. ⟨10.1002/biot.201300510⟩. ⟨hal-02135170⟩
  • David Brevet, Ouahiba Hocine, Anthony Delalande, Laurence Raehm, Clarence Charnay, et al.. Improved gene transfer with histidine-​functionalized mesoporous silica nanoparticles. International Journal of Pharmaceutics, 2014, pp.197-205. ⟨10.1016/j.ijpharm.2014.05.020⟩. ⟨hal-01068026⟩
  • Cristine Gonçalves, Mathieu Berchel, Marie-Pierre Gosselin, Virginie Malard, Hervé Cheradame, et al.. Lipopolyplexes comprising imidazole/imidazolium lipophosphoramidate, histidinylated polyethyleneimine and siRNA as efficient formulation for siRNA transfection. International Journal of Pharmaceutics, 2014, 460 (1-2), pp.264-272. ⟨10.1016/j.ijpharm.2013.11.005⟩. ⟨hal-01179049⟩
  • Cristine Gonçalves, Fabian Gross, Philippe Guégan, Hervé Cheradame, Patrick Midoux. A robust transfection reagent for the transfection of CHO and HEK293 cells and production of recombinant proteins and lentiviral particles - PTG1. Biotechnology Journal, 2014, 9 (11), pp.1380-1388. ⟨10.1002/biot.201400324⟩. ⟨hal-01179065⟩
  • Ulysse Asseline, Cristine Gonçalves, Chantal Pichon, Patrick Midoux. Improved nuclear delivery of antisense 2′-Ome RNA by conjugation with the histidine-rich peptide H5WYG. The Journal of Gene Medicine, 2014, 16 (7-8), pp.157-165. ⟨10.1002/jgm.2773⟩. ⟨hal-01175483⟩
  • Jana Kasparkova, Thomas Thibault, Hana Kostrhunova, Jana Stepankova, Marie Vojtiskova, et al.. Different affinity of nuclear factor-kappa B proteins to DNA modified by antitumor cisplatin and its clinically ineffective trans isomer. FEBS Journal, 2014, 281 (5), pp.:1393-1408. ⟨10.1111/febs.12711⟩. ⟨hal-01179156⟩
  • Benoit Maury, Cristine Gonçalves, Guillaume Tresset, Mehdi Zeghal, Hervé Cheradame, et al.. Influence of pDNA availability on transfection efficiency of polyplexes in non-proliferative cells.. Biomaterials, 2014, 35 (22), pp.5977-5985. ⟨10.1016/j.biomaterials.2014.04.007⟩. ⟨hal-01179393⟩
  • S Mahindhoratep, H Ait Bouda, Nelly El Shafey, D Scherman, A Kichler, et al.. NF-kB related transgene expression in mouse tibial cranial muscle after pDNA injection followed or not by electrotransfer.. BBA - Biochimica et Biophysica Acta, 2014, 1840 (11), pp.3257-3263. ⟨hal-01179311⟩
  • Mathieu Berchel, Stéphanie Le Corre, Tony Le Gall, Hélène Couthon, Jean-Pierre Haelters, et al.. Trimethylarsonium-Based Cationic Phospholipids for Gene Delivery. Phosphorus, Sulfur, and Silicon and the Related Elements, 2013, 188 (1-3), pp.91-94. ⟨10.1080/10426507.2012.741161⟩. ⟨hal-02070718⟩
  • Jean-Pierre Gomez, Chantal Pichon, Patrick Midoux. Ability of plasmid DNA complexed with histidinylated lPEI and lPEI to cross in vitro lung and muscle vascular endothelial barriers. Gene, 2013, 525 (2), pp.182-190. ⟨10.1016/j.gene.2013.03.055⟩. ⟨hal-02070843⟩
  • Lucie Pigeon, Cristine Gonçalves, David Gosset, Chantal Pichon, Patrick Midoux. An E3-14.7K Peptide that Promotes Microtubules-Mediated Transport of Plasmid DNA Increases Polyplexes Transfection Efficiency.. Small, 2013, 9 (22), pp.3845-3851. ⟨10.1002/smll.201300217⟩. ⟨hal-00840172⟩
  • Alice Dubois, Patrick Midoux, Delphine Gras, Mustapha Si-Tahar, Deborah Brea, et al.. Poly- l -Lysine Compacts DNA, Kills Bacteria, and Improves Protease Inhibition in Cystic Fibrosis Sputum. American Journal of Respiratory and Critical Care Medicine, 2013, 188 (6), pp.703-709. ⟨10.1164/rccm.201305-0912OC⟩. ⟨hal-02070798⟩
  • Yuliya Sedletska, Françoise Culard, Patrick Midoux, Jean-Marc Malinge. Interaction studies of muts and mutl with DNA containing the major cisplatin lesion and its mismatched counterpart under equilibrium and nonequilibrium conditions.. Biopolymers, 2013, 99 (9), pp.636-47. ⟨10.1002/bip.22232⟩. ⟨hal-00874890⟩
  • Anthony Delalande, Spiros Kotopoulis, Michiel Postema, Patrick Midoux, Chantal Pichon. Sonoporation: mechanistic insights and ongoing challenges for gene transfer. Gene, 2013, 525 (2), pp.191-199. ⟨10.1016/j.gene.2013.03.095⟩. ⟨hal-03195625⟩
  • Safia Ezzine, Georges Vassaux, Bruno Pitard, Benoit Barteau, Jean-Marc Malinge, et al.. RILES, a novel method for temporal analysis of the in vivo regulation of miRNA expression.. Nucleic Acids Research, 2013, epub ahead of print. ⟨10.1093/nar/gkt797⟩. ⟨hal-00874881⟩
  • Solenne Bire, David Gosset, Gwenhael Jegot, Patrick Midoux, Chantal Pichon, et al.. Exogenous mRNA delivery and bioavailability in gene transfer mediated by piggyBac transposition. BMC Biotechnology, 2013, 13, pp.1-15. ⟨10.1186/1472-6750-13-75⟩. ⟨hal-01129780⟩
  • Federico Perche, Olivier Lambert, Mathieu Berchel, Paul-Alain Jaffres, Chantal Pichon, et al.. Gene transfer by histidylated lipopolyplexes: A dehydration method allowing preservation of their physicochemical parameters and transfection efficiency. International Journal of Pharmaceutics, 2012, 423 (1), pp.144 - 150. ⟨10.1016/j.ijpharm.2011.04.009⟩. ⟨hal-02995807⟩
  • Ludivine Billiet, Jean-Pierre Gomez, Mathieu Berchel, Paul-Alain Jaffres, Tony Le Gall, et al.. Gene transfer by chemical vectors, and endocytosis routes of polyplexes, lipoplexes and lipopolyplexes in a myoblast cell line.. Biomaterials, 2012, 33 (10), pp.2980-2990. ⟨10.1016/j.biomaterials.2011.12.027⟩. ⟨hal-00721795⟩
  • Anthony Delalande, Michiel Postema, Nathalie Mignet, Patrick Midoux, Chantal Pichon. Ultrasound and microbubble-assisted gene delivery: recent advances and ongoing challenges. Therapeutic Delivery, 2012, 3 (10), pp.1199-1215. ⟨10.4155/TDE.12.100⟩. ⟨hal-03193228⟩
  • Mathieu Berchel, Tony Le Gall, Hélène Couthon, Jean-Pierre Haelters, Tristan Montier, et al.. Lipophosphonate/lipophosphoramidates: a family of synthetic vectors efficient for gene delivery.. Biochimie, 2012, 94 (1), pp.33-41. ⟨10.1016/j.biochi.2011.07.026⟩. ⟨hal-00721772⟩
  • Anthony Delalande, Michiel Postema, Nathalie Mignet, Patrick Midoux, Chantal Pichon. Ultrasound and microbubble-assisted gene delivery: recent advances and ongoing challenges.. Ther Deliv, 2012, 3 (10), pp.1199-1215. ⟨hal-00817350⟩
  • Emilie Bertrand, Cristine Gonçalves, Ludivine Billiet, Jean Pierre Gomez, Chantal Pichon, et al.. Histidinylated linear PEI: a new efficient non-toxic polymer for gene transfer.. Chemical Communications, 2011, 47 (46), pp.12547-12549. ⟨10.1039/c1cc15716g⟩. ⟨hal-00720539⟩
  • Paul-Alain Jaffres, Aurore Fraix, Christophe Lorilleux, Mathieu Berchel, Hélène Couthon, et al.. New Lipo-Phosphoramidates for Gene Delivery. Phosphorus, Sulfur, and Silicon and the Related Elements, 2011, 186 (4), pp.918-920. ⟨10.1080/10426507.2010.522639⟩. ⟨hal-00614938⟩
  • Véronique Bennevault-Celton, Allan Urbach, Olivier Martin, Chantal Pichon, Philippe Guégan, et al.. Supramolecular assemblies of histidinylated α-cyclodextrin in the presence of DNA scaffold during CDplexes formation.. Bioconjugate Chemistry, 2011, 22 (12), pp.2404-14. ⟨10.1021/bc200167p⟩. ⟨hal-00720527⟩
  • Mathieu Berchel, Jean-Piere Haelters, Hélène Couthon, Laure Burel-Deschamps, Patrick Midoux, et al.. Modular Construction of Fluorescent Lipophosphoramidates by Click Chemistry. European Journal of Organic Chemistry, 2011, 31, pp.6294-6303. ⟨10.1002/ejoc.201100900⟩. ⟨hal-00720537⟩
  • Federico Perche, David Gosset, Mathieu Mével, Marie-Laure Miramon, Jean-Jacques Yaouanc, et al.. Selective gene delivery in dendritic cells with mannosylated and histidylated lipopolyplexes.. Journal of Drug Targeting, 2011, 19 (5), pp.315-25. ⟨10.3109/1061186X.2010.504262⟩. ⟨hal-00753554⟩
  • Anthony Delalande, Ayache Bouakaz, Gilles Renault, Flore Tabareau, Spiros Kotopoulis, et al.. Ultrasound and microbubble-assisted gene delivery in Achilles tendons: long lasting gene expression and restoration of fibromodulin KO phenotype. Journal of Controlled Release, 2011, 156 (2), pp.223-230. ⟨10.1016/j.jconrel.2011.08.020⟩. ⟨hal-03195121⟩
  • Federico Perche, Thierry Benvegnu, Mathieu Berchel, Loic Lebegue, Chantal Pichon, et al.. Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA.. Nanomedicine: Nanotechnology, Biology and Medicine, 2011, 7 (4), pp.445-53. ⟨10.1016/j.nano.2010.12.010⟩. ⟨hal-00754373⟩
  • Anthony Delalande, Michel-Francis Bureau, Patrick Midoux, Ayache Bouakaz, Chantal Pichon. Ultrasound-assisted microbubbles gene transfer in tendons for gene therapy. Ultrasonics Sonochemistry, 2010, 50 (2), pp.269-272. ⟨10.1016/j.ultras.2009.09.035⟩. ⟨hal-00529321⟩
  • Chantal Pichon, Ludivine Billiet, Patrick Midoux. Chemical vectors for gene delivery: uptake and intracellular trafficking. Current Opinion in Biotechnology, 2010, 21 (5), pp.640-645. ⟨10.1016/j.copbio.2010.07.003⟩. ⟨hal-00602488⟩
  • K. Kaddur, L. Lebegue, F. Tranquart, P. Midoux, C. Pichon, et al.. Transient transmembrane release of green fluorescent proteins with sonoporation. IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2010, 57 (7), pp.1558-1567. ⟨10.1109/TUFFC.2010.1586⟩. ⟨hal-00529340⟩
  • Matthieu Fisichella, Hinda Dabboue, Sanjib Bhattacharyya, Gerald Lelong, Marie-Louise Saboungi, et al.. Uptake of Functionalized Mesoporous Silica Nanoparticles by Human Cancer Cells. Journal of Nanoscience and Nanotechnology, 2010, 10 (4), pp.314-2324. ⟨10.1166/jnn.2010.1917⟩. ⟨hal-00529333⟩
  • Arnaud Suwalski, Hinda Dabboue, Anthony Delalande, Sabine F. Bensamoun, Francis Canon, et al.. Accelerated Achilles tendon healing by PDGF gene delivery with mesoporous silica nanoparticles. Biomaterials, 2010, 31 (19), pp.5237-5245. ⟨10.1016/j.biomaterials.2010.02.077⟩. ⟨hal-00529475⟩
  • Corinne Bure, Régine Maget, Agnès F. Delmas, Chantal Pichon, Patrick Midoux. Histidine-rich peptide: evidence for a single zinc-binding site on H5WYG peptide that promotes membrane fusion at neutral pH. Journal of Mass Spectrometry, 2009, 44 (1), pp.81-89. ⟨10.1002/jms.1473⟩. ⟨hal-00521834⟩
  • Corinne Bure, Chantal Pichon, Patrick Midoux. Involvement of histidines 11, 15 and 19 in the binding of zinc to the fusogenic H5WYG peptide. Journal of Mass Spectrometry, 2009, 44 (8), pp.1163-1170. ⟨10.1002/jms.1591⟩. ⟨hal-00521851⟩
  • Marie Breton, Jeanne Leblond, Johanne Seguin, Patrick Midoux, Daniel Scherman, et al.. Comparative gene transfer between cationic and thiourea lipoplexes. The Journal of Gene Medicine, 2009, 12 (1), pp.45-54. ⟨10.1002/jgm.1417⟩. ⟨hal-02512540⟩
  • Patrick Midoux, Chantal Pichon, Jean-Jacques Yaouanc, Paul-Alain Jaffres. Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers. British Journal of Pharmacology, 2009, 157 (2), pp.166-178. ⟨10.1111/j.1476-5381.2009.00288.x⟩. ⟨hal-00525108⟩
  • Cristine Gonçalves, Maryvonne Ardourel, Martine Decoville, Gilles Breuzard, Patrick Midoux, et al.. An optimized extended DNA kappa B site that enhances plasmid DNA nuclear import and gene expression. The Journal of Gene Medicine, 2009, 11 (5), pp.401-411. ⟨10.1002/jgm.1312⟩. ⟨hal-00522437⟩
  • Kadija Kaddur, Anthony Delalande, François Tranquart, Patrick Midoux, Chantal Pichon, et al.. Extraction of green fluorescent proteins with sonoporation. Journal of the Acoustical Society of America, 2008, 123 (5), pp.3218-3218. ⟨10.1121/1.2933412⟩. ⟨hal-02128161⟩
  • Mathieu Mével, Jean-Jacques Yaouanc, Pascal Laurent, Claude Clément, Dominique Cartier, et al.. Cationic Lipids Based on Phosphonate and Phosphoramidate Chemistry: Synthesis and Application to Gene Therapy. Phosphorus, Sulfur, and Silicon and the Related Elements, 2008, 183 (2-3), pp.460-468. ⟨10.1080/10426500701761300⟩. ⟨hal-01580434⟩
  • M. Mevel, C. Neveu, Cristine Goncalves, J.-J. Yaouanc, Chantal Pichon, et al.. Novel neutral imidazole-lipophosphoramides for transfection assays. Chemical Communications, 2008, 27, pp.3124-3126. ⟨10.1039/b805226c⟩. ⟨hal-00518192⟩
  • Patrick Midoux, Gilles Breuzard, Jean-Pierre Gomez, Chantal Pichon. Polymer-Based Gene Delivery: A Current Review on the Uptake and Intracellular Trafficking of Polyplexes. Current Gene Therapy, 2008, 8 (5), pp.335-352. ⟨hal-00518197⟩
  • M. Mevel, Gilles Breuzard, J.-J. Yaouanc, J.-C. Clement, P. Lehn, et al.. Synthesis and transfection activity of new cationic phosphoramidate lipids: High efficiency of an imidazolium derivative. ChemBioChem, 2008, 9 (9), pp.1462-1471. ⟨10.1002/cbic.200700727⟩. ⟨hal-00518184⟩
  • Chantal Pichon, Kadija Kaddur, Patrick Midoux, François Tranquart, Ayache Bouakaz. Recent advances in gene delivery with ultrasound and microbubbles. Journal of Experimental Nanoscience, 2008, 3 (1), pp.17-40. ⟨10.1080/17458080801993422⟩. ⟨hal-00518203⟩
  • Gilles Breuzard, Magdalena Tertil, Cristine Gonçalves, Hervé Cheradame, Philippe Géguan, et al.. Nuclear delivery of NFkappaB-assisted DNA/polymer complexes: plasmid DNA quantitation by confocal laser scanning microscopy and evidence of nuclear polyplexes by FRET imaging.. Nucleic Acids Research, 2008, 36 (12), pp.e71. ⟨10.1093/nar/gkn287⟩. ⟨hal-00408004⟩
  • Valerie Boutin, Alain Legrand, Roger Mayer, Maurice Nachtigal, Michel Monsigny, et al.. Glycofection: The Ubiquitous Roles of Sugar Bound on Glycoplexes. Drug Delivery, 2008, 6 (1), pp.45-50. ⟨10.1080/107175499267156⟩. ⟨hal-02138035⟩
  • M. Mockey, E Bourseau, V Chandrashekhar, A. Chaudhuri, S. Lafosse, et al.. mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes. Cancer Gene Therapy, 2007, 14 (9), pp.802-814. ⟨10.1038/sj.cgt.7701072⟩. ⟨hal-03065277⟩
  • M. Mockey, E. Bourseau, V. Chandrashekhar, A. Chaudhuri, S. Lafosse, et al.. mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes.. Cancer Gene Therapy, 2007, 14 (9), pp.802-14. ⟨10.1038/sj.cgt.7701072⟩. ⟨hal-00318514⟩
  • Gilles Breuzard, M. Tertil, Chantal Pichon, Patrick Midoux. Intracellular trafficking and nuclear import of polyplexes by FRET coupled with cellular imaging. Human Gene Therapy, 2007, 18, pp.1048. ⟨hal-00275215⟩
  • Eric Mennesson, Patrick Erbacher, Mateusz Kuzak, Claudine Kieda, Patrick Midoux, et al.. DNA/cationic polymer complex attachment on a human vascular endothelial cell monolayer exposed to a steady laminar flow. Journal of Controlled Release, 2006, 114 (3), pp.389-397. ⟨10.1016/j.jconrel.2006.06.006⟩. ⟨hal-00112894⟩
  • M. Mockey, C. Goncalves, F.P. Dupuy, F.M. Lemoine, C. Pichon, et al.. mRNA transfection of dendritic cells: synergistic effect of ARCA mRNA capping with Poly(A) chains in cis and in trans for a high protein expression level. Biochemical and Biophysical Research Communications, 2006, 340, pp.1062-1068. ⟨10.1016/j.bbrc.2005.12.105⟩. ⟨hal-00088921⟩
  • E. Mennesson, P. Erbacher, V. Piller, C. Kieda, P. Midoux, et al.. Transfection efficiency and uptake process of polyplexes in human lung endothetial cells: a comparative study in non-polarized and polarized cells. The Journal of Gene Medicine, 2005, 7, pp.729-738. ⟨hal-00088642⟩
  • R.S. Singh, C. Gonçalves, P. Sandrin, C. Pichon, P. Midoux, et al.. On the gene delivery efficacies of pH-sensitive cationic lipids via endosomal protonation: a chemical biology investigation. Chemistry & biology, 2004, 11, pp.713-723. ⟨hal-00088426⟩
  • C. Goncalves, E. Mennesson, R. Fuchs, Gorvel J.P., Patrick Midoux, et al.. Macropinocytosis of polyplexes and recycling of plasmid via the clathrin-dependant pathway impair the transfection efficiency into human hepatocarcinoma cells. Molecular Therapy, 2004, 10, pp.373-385. ⟨hal-00113047⟩
  • Ibrahim Elmadbouh, Patrick Rossignol, Olivier Meilhac, Roger Vranckx, Chantal Pichon, et al.. Optimization of in vitro vascular cell transfection with non-viral vectors for in vivo applications. The Journal of Gene Medicine, 2004, 6 (10), pp.1112-1124. ⟨hal-00014241⟩
  • T. Montier, P. Delépine, C. Pichon, C. Férec, D.J. Porteous, et al.. Non-viral vectors in cystic fibrosis gene therapy: progress and challenges. Trends in biotechnology., 2004, 22, pp.586-592. ⟨hal-00088424⟩
  • A. Kamal, B.A. Kumar, M. Arifuddin, P. Midoux. An efficient and facile nitration of phenols with nitric acid/zinc chloride under ultrasonic conditions. Ultrasonics Sonochemistry, 2004, 11, pp.455-457. ⟨hal-00088378⟩
  • Chantal Pichon, Eric Le Cam, Brigitte Guérin, Dominique Coulaud, Etienne Delain, et al.. Poly[Lys-(AEDTP)]: A Cationic Polymer That Allows Dissociation of pDNA/Cationic Polymer Complexes in a Reductive Medium and Enhances Polyfection. Bioconjugate Chemistry, 2002, 13 (1), pp.76-82. ⟨10.1021/bc015503o⟩. ⟨hal-03065338⟩
  • Christine Gonçalves, Chantal Pichon, Brigitte Guérin, Patrick Midoux. Intracellular processing and stability of DNA complexed with histidylated polylysine conjugates. The Journal of Gene Medicine, 2002, 4 (3), pp.271-281. ⟨10.1002/jgm.277⟩. ⟨hal-02135970⟩
  • V Kumar, Chantal Pichon, M. Refregiers, B Guerin, P. Midoux, et al.. Single histidine residue in head-group region is sufficient to impart remarkable gene transfection properties to cationic lipids: evidence for histidine-mediated membrane fusion at acidic pH. Gene Therapy, 2002, 10 (15), pp.1206 - 1215. ⟨10.1038/sj.gt.3301979⟩. ⟨hal-01596052⟩
  • Patrick Midoux, Eric Le Cam, Dominique Coulaud, Etienne Delain, Chantal Pichon. Histidine containing peptides and polypeptides as nucleic acid vectors.. Somatic Cell and Molecular Genetics, 2002, 27 (1-6), pp.27-47. ⟨10.1023/a:1022931923153⟩. ⟨hal-03065331⟩
  • Chantal Pichon, Brigitte Guérin, Matthieu M. Refregiers, Christine Gonçalves, Paul Vigny, et al.. Zinc improves gene transfer mediated by DNA/cationic polymer complexes. The Journal of Gene Medicine, 2002, 4 (5), pp.548 - 559. ⟨10.1002/jgm.303⟩. ⟨hal-01596013⟩
  • J Ohan, M.A Gilbert, G Leseche, Y Panis, P. Midoux, et al.. Nonviral gene transfer into primary cultures of human and porcine mesothelial cells.. In Vitro Cellular & Developmental Biology - Animal, 2001, 37 (7), pp.402-7. ⟨hal-02161118⟩
  • Chantal Pichon, C Gonçalves, P. Midoux. Histidine-rich peptides and polymers for nucleic acids delivery.. Advanced Drug Delivery Reviews, 2001, 53 (1), pp.75-94. ⟨hal-02135973⟩
  • M Bello Roufaï, P. Midoux. Histidylated polylysine as DNA vector: elevation of the imidazole protonation and reduced cellular uptake without change in the polyfection efficiency of serum stabilized negative polyplexes.. Bioconjugate Chemistry, 2001, 12 (1), pp.92-9. ⟨10.1021/bc0000738⟩. ⟨hal-02161122⟩
  • J.C Allo, Patrick Midoux, Marc Merten, Evelyne Souil, Joanna Lipecka, et al.. Efficient Gene Transfer into Human Normal and Cystic Fibrosis Tracheal Gland Serous Cells with Synthetic Vectors. American Journal of Respiratory Cell and Molecular Biology, 2000, 22 (2), pp.166-175. ⟨10.1165/ajrcmb.22.2.3722⟩. ⟨hal-02161132⟩
  • Chantal Pichon, Mahajoub Bello Roufaï, Michel Monsigny, Patrick Midoux. Histidylated oligolysines increase the transmembrane passage and the biological activity of antisense oligonucleotides. Nucleic Acids Research, 2000, 28 (2), pp.504-512. ⟨10.1093/nar/28.2.504⟩. ⟨hal-02135979⟩
  • Isabelle Fajac, J.C Allo, Evelyne Souil, Marc Merten, Chantal Pichon, et al.. Histidylated polylysine as a synthetic vector for gene transfer into immortalized cystic fibrosis airway surface and airway gland serous cells. The Journal of Gene Medicine, 2000, 2 (5), pp.368-378. 3.0.CO;2-F">⟨10.1002/1521-2254(200009/10)2:5<368::AID-JGM118>3.0.CO;2-F⟩. ⟨hal-02135988⟩
  • I. Freulon, M. Monsigny, P. Midoux, R. Mayer. Spacer length dependence on the efficiency of dimeric anionic peptides in gene transfer by glycosylated polylysine/plasmid complexes.. Bioscience Reports, 2000, 20 (5), pp.383-398. ⟨10.1023/a:1010382001654⟩. ⟨hal-02161127⟩
  • Antoine Kichler, Isabelle Freulon, Valerie Boutin, Roger Mayer, Michel Monsigny, et al.. GlycofectionTM in the presence of anionic fusogenic peptides: a study of the parameters affecting the peptide-mediated enhancement of the transfection efficiency. The Journal of Gene Medicine, 1999, 1 (2), pp.134-143. 3.0.CO;2-B">⟨10.1002/(SICI)1521-2254(199903/04)1:2<134::AID-JGM17>3.0.CO;2-B⟩. ⟨hal-02161144⟩
  • Patrick Midoux, Michel Monsigny. Efficient Gene Transfer by Histidylated Polylysine/pDNA Complexes. Bioconjugate Chemistry, 1999, 10 (3), pp.406-411. ⟨10.1021/bc9801070⟩. ⟨hal-02161145⟩
  • Isabelle Fajac, Pascale Briand, Michel Monsigny, Patrick Midoux. Sugar-Mediated Uptake of Glycosylated Polylysines and Gene Transfer into Normal and Cystic Fibrosis Airway Epithelial Cells. Human Gene Therapy, 1999, 10 (3), pp.395-406. ⟨10.1089/10430349950018841⟩. ⟨hal-02161152⟩
  • Christophe Quétard, Sylvain Bourgerie, Nadia Normand-Sdiqui, Roger Mayer, Gérard Strecker, et al.. Novel Glycosynthons for Glycoconjugate Preparation: Oligosaccharylpyroglutamylanilide Derivatives. Bioconjugate Chemistry, 1998, 9 (2), pp.268-276. ⟨10.1021/bc970122p⟩. ⟨hal-02161157⟩
  • Patrick Midoux, Antoine Kichler, Valerie Boutin, Jean-Claude Maurizot, Michel Monsigny. Membrane Permeabilization and Efficient Gene Transfer by a Peptide Containing Several Histidines. Bioconjugate Chemistry, 1998, 9 (2), pp.260-267. ⟨10.1021/bc9701611⟩. ⟨hal-02161162⟩
  • M Monsigny, C. Quétard, S. Bourgerie, D. Delay, Chantal Pichon, et al.. Glycotargeting: the preparation of glyco-amino acids and derivatives from unprotected reducing sugars.. Biochimie, 1998, 80 (2), pp.99-108. ⟨hal-02136005⟩
  • Patrick Erbacher, Annie Claude Roche, Michel Monsigny, Patrick Midoux. Specific Gene Transfer Based on Biotinylated and Gluconoylated Polylysine/Plasmid Complexes. Drug Delivery, 1997, 4 (3), pp.173-179. ⟨10.3109/10717549709051889⟩. ⟨hal-02161332⟩
  • A.J. Stewart, Chantal Pichon, Patrick Midoux, R. Mayer, Michel Monsigny, et al.. Fluorescent labelling of unmodified phosphorothioate oligodeoxynucleotides: Synthesis and characterization. New Journal of Chemistry, 1997, 21 (1), pp.87-98. ⟨hal-02161369⟩
  • Wouter Kollen, Patrick Erbacher, Patrick Midoux, Annie-Claude Roche, Michel Monsigny, et al.. Glycosylated Polylysines. Nonviral vectors for gene transfer into cystic fibrosis airway epithelial cells.. Chest, 1997, 111 (6), pp.95S-96S. ⟨10.1378/chest.111.6_supplement.95s⟩. ⟨hal-02161319⟩
  • Patrick Erbacher, Annie Claude Roche, Michel Monsigny, Patrick Midoux. The reduction of the positive charges of polylysine by partial gluconoylation increases the transfection efficiency of polylysine/DNA complexes. Biochimica et Biophysica Acta:Biomembranes, 1997, 1324 (1), pp.27-36. ⟨10.1016/s0005-2736(96)00204-0⟩. ⟨hal-02161372⟩
  • Chantal Pichon, Isabelle Freulon, Patrick Midoux, Roger Mayer, Michel Monsigny, et al.. Cytosolic and Nuclear Delivery of Oligonucleotides Mediated by an Amphiphilic Anionic Peptide. Antisense and Nucleic Acid Drug Development, 1997, 7 (4), pp.335-343. ⟨10.1089/oli.1.1997.7.335⟩. ⟨hal-02136009⟩
  • Alexandre Avraméas, Dorian Mcilroy, Anne Hosmalin, Brigitte Autran, Patrice Debré, et al.. Expression of a mannose/fucose membrane lectin on human dendritic cells. European Journal of Immunology, 1996, 26 (2), pp.394-400. ⟨10.1002/eji.1830260219⟩. ⟨hal-02161396⟩
  • Patrick Erbacher, Marie-Thérèse Bousser, Jacques Raimond, Michel Monsigny, Patrick Midoux, et al.. Gene Transfer by DNA/Glycosylated Polylysine Complexes into Human Blood Monocyte-Derived Macrophages. Human Gene Therapy, 1996, 7 (6), pp.721-729. ⟨10.1089/hum.1996.7.6-721⟩. ⟨hal-02161390⟩
  • Wouter Kollen, Patrick Midoux, Patrick Erbacher, Alex Yip, Annie Claude Roche, et al.. Gluconoylated and Glycosylated Polylysines As Vectors for Gene Transfer into Cystic Fibrosis Airway Epithelial Cells. Human Gene Therapy, 1996, 7 (13), pp.1577-1586. ⟨10.1089/hum.1996.7.13-1577⟩. ⟨hal-02161378⟩
  • A. Stewart, Chantal Pichon, L Meunier, P Midoux, M. Monsigny, et al.. Enhanced biological activity of antisense oligonucleotides complexed with glycosylated poly-L-lysine.. Molecular Pharmacology, 1996, 50 (6), pp.1487-94. ⟨hal-02136015⟩
  • Patrick Erbacher, Annie Claude Roche, Michel Monsigny, Patrick Midoux. Putative Role of Chloroquine in Gene Transfer into a Human Hepatoma Cell Line by DNA/Lactosylated Polylysine Complexes. Experimental Cell Research, 1996, 225 (1), pp.186-194. ⟨10.1006/excr.1996.0169⟩. ⟨hal-02161382⟩
  • P Erbacher, A.C. Roche, M. Monsigny, P. Midoux. Glycosylated polylysine/DNA complexes: gene transfer efficiency in relation with the size and the sugar substitution level of glycosylated polylysines and with the plasmid size.. Bioconjugate Chemistry, 1995, 6 (4), pp.401-10. ⟨10.1021/bc00034a010⟩. ⟨hal-02161414⟩
  • Patrick Midoux, Roger Mayer, Michel Monsigny. Membrane permeabilization by α-helical peptides: a flow cytometry study. Biochimica et Biophysica Acta:Biomembranes, 1995, 1239 (2), pp.249-256. ⟨10.1016/0005-2736(95)00163-w⟩. ⟨hal-02161407⟩
  • Michel Monsigny, Annie-Claude Roche, Patrick Midoux, Roger Mayer. Glycoconjugates as carriers for specific delivery of therapeutic drugs and genes. Advanced Drug Delivery Reviews, 1994, 14 (1), pp.1-24. ⟨10.1016/0169-409X(94)90003-5⟩. ⟨hal-02163748⟩
  • Nadia Sdiqui, Khalil Arar, Patrick Midoux, Roger Mayer, Michel Monsigny, et al.. Inhibition of Human Mammary Cell Line Proliferation by Membrane Lectin-Mediated Uptake of Ha- ras Antisense Oligodeoxynucleotide. Drug Delivery, 1994, 2 (1), pp.63-72. ⟨10.3109/10717549509031353⟩. ⟨hal-02161404⟩
  • V. Carpentier, Patrick Midoux, M. Monsigny, A.C. Roche. Endocytosis of alpha 1-acid glycoprotein variants by human monocytic lineage cells.. Biology of the Cell, 1993, 77 (2), pp.187-93. ⟨10.1016/S0248-4900(05)80187-X⟩. ⟨hal-02161453⟩
  • M. Monsigny, P. Midoux, A.C. Roche. Perspectives ex vivo et in vivo pour la thérapie génique, de la transfection sélective à l'aide de complexes plasmide-polylysine ciblés. médecine/sciences, 1993, 9 (4), pp.441. ⟨10.4267/10608/2938⟩. ⟨hal-02163755⟩
  • Patrick Midoux, Christina Mendes, Alain Legrand, Jacques Raimond, Roger Mayer, et al.. Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells. Nucleic Acids Research, 1993, 21 (4), pp.871-878. ⟨10.1093/nar/21.4.871⟩. ⟨hal-02138456⟩
  • N Bonfils, C. Depierreux, P. Midoux, N.T. Thuong, M. Monsigny, et al.. Drug targeting: synthesis and endocytosis of oligonucleotide-neoglycoprotein conjugates. Nucleic Acids Research, 1992, 20 (17), pp.4621-4629. ⟨10.1093/nar/20.17.4621⟩. ⟨hal-02161479⟩
  • Patrick Midoux, A. Martin, B Collet, M. Monsigny, A.C. Roche, et al.. Activation of mouse macrophages by muramyl dipeptide coupled with an anti-macrophage monoclonal antibody.. Bioconjugate Chemistry, 1992, 3 (2), pp.194-9. ⟨10.1021/bc00014a016⟩. ⟨hal-02161456⟩
  • E Bonfils, C. Mendes, A.C. Roche, M. Monsigny, P. Midoux. Uptake by macrophages of a biotinylated oligo-alpha-deoxythymidylate by using mannosylated streptavidin.. Bioconjugate Chemistry, 1992, 3 (4), pp.277-284. ⟨10.1021/bc00016a004⟩. ⟨hal-02161474⟩
  • V Pimpaneau, Patrick Midoux, M. Monsigny, A.C. Roche. Characterization and isolation of an intracellular D-mannose-specific receptor from human promyelocytic HL60 cells.. Carbohydrate Research, 1991, 213, pp.95-108. ⟨10.1016/S0008-6215(00)90601-3⟩. ⟨hal-02162388⟩
  • P Breton, Patrick Midoux, Christian Petit, M Bousser, A.C Roche, et al.. Production of macrophage-derived cytotoxic factor by N-[3-[(carbamoylmethyl)thio]propionylated] neoglycoproteins.. Bioconjugate Chemistry, 1991, 2 (1), pp.16-8. ⟨hal-02162393⟩
  • Patrick Midoux, Eric Negre, Annie-Claude Roche, Roger Mayer, Michel Monsigny, et al.. Drug targeting: Anti-HSV-1 activity of mannosylated polymer-bound 9-(2-phosphonylmethoxyethyl)adenine. Biochemical and Biophysical Research Communications, 1990, 167 (3), pp.1044-1049. ⟨10.1016/0006-291x(90)90628-z⟩. ⟨hal-02163192⟩
  • M Monsigny, Patrick Midoux, C. Depierreux, C Bebear, M.T Le Bris, et al.. Benzoxazinone kanamycin A conjugate. A new fluorescent probe suitable to detect mycoplasmas in cell culture.. Biology of the Cell, 1990, 70 (3), pp.101-105. ⟨10.1016/0248-4900(90)90365-A⟩. ⟨hal-02163189⟩
  • D Derrien, Patrick Midoux, Christian Petit, E. Negre, R. Mayer, et al.. Muramyl dipeptide bound to poly-L-lysine substituted with mannose and gluconoyl residues as macrophage activators.. Glycoconjugate Journal, 1989, 6 (2), pp.241-255. ⟨10.1007/BF01050652⟩. ⟨hal-02163397⟩
  • Patrick Midoux, Christian Petit, P Pellen, L Toujas, M. Monsigny, et al.. Macrophage antigens associated with adhesion: identification by a monoclonal antibody specific for Lewis lung carcinoma cells.. Experimental Cell Research, 1989, 183 (1), pp.168-178. ⟨10.1016/0014-4827(89)90427-8⟩. ⟨hal-02163384⟩
  • M Monsigny, Patrick Midoux, M.T Le Bris, A.C Roche, B Valeur. Benzoxazinone derivatives: new fluorescent probes for two-color flow cytometry analysis using one excitation wavelength.. Biology of the Cell, 1989, 67 (2), pp.193-200. ⟨10.1111/j.1768-322X.1989.tb00862.x⟩. ⟨hal-02163198⟩
  • V Pimpaneau, Patrick Midoux, Geoffroy Durand, P de Baetselier, M. Monsigny, et al.. Endocytosis of alpha 1-acid glycoprotein variants and of neoglycoproteins containing mannose derivatives by a mouse hybridoma cell line (2C11-12). Comparison with mouse peritoneal macrophages.. Glycoconjugate Journal, 1989, 6 (4), pp.561-574. ⟨10.1007/BF01053778⟩. ⟨hal-02163197⟩
  • M. Monsigny, A.C Roche, P. Midoux. Endogenous Lectins and Drug Targeting. Annals of the New York Academy of Sciences, 1988, 551, pp.399-414. ⟨10.1111/j.1749-6632.1988.tb22373.x⟩. ⟨hal-02163799⟩
  • M Monsigny, Annie Claude Roche, C. Kieda, P. Midoux, A Obrénovitch. Characterization and biological implications of membrane lectins in tumor, lymphoid and myeloid cells.. Biochimie, 1988, 70 (11), pp.1633-49. ⟨10.1016/0300-9084(88)90299-4⟩. ⟨hal-02163758⟩
  • Hj Gabius, R Engelhardt, T Hellmann, Patrick Midoux, M. Monsigny, et al.. Characterization of membrane lectins in human colon carcinoma cells by flow cytofluorometry, drug targeting and affinity chromatography.. Anticancer Research, 1987, 7 (1), pp.109-112. ⟨hal-02163405⟩
  • Patrick Midoux, Annie-Claude Roche, Michel Monsigny. Quantitation of the binding, uptake, and degradation of fluoresceinylated neoglycoproteins by flow cytometry. Cytometry, 1987, 8 (3), pp.327-334. ⟨10.1002/cyto.990080314⟩. ⟨hal-02163401⟩
  • Patrick Midoux, A.C Roche, M. Monsigny. Estimation of the degradation of endocytosed material by flow cytofluorometry using two neoglycoproteins containing different numbers of fluorescein molecules.. Biology of the Cell, 1986, 58 (3), pp.221-225. ⟨hal-02163590⟩
  • A Sève, J. Hubert, D. Bouvier, C. Bourgeois, P. Midoux, et al.. Analysis of sugar-binding sites in mammalian cell nuclei by quantitative flow microfluorometry.. Proceedings of the National Academy of Sciences of the United States of America, 1986, 83 (16), pp.5997-6001. ⟨10.1073/pnas.83.16.5997⟩. ⟨hal-02163583⟩
  • Annie-Claude Roche, Patrick Midoux, Philippe Bouchard, Michel Monsigny. Membrane lectins on human monocytes. Maturation-dependent modulation of 6-phosphomannose and mannose receptors.. FEBS Letters, 1985, 193 (1), pp.63-68. ⟨10.1016/0014-5793(85)80080-6⟩. ⟨hal-02163594⟩
  • Patrick Midoux, Annie-Claude Roche, M. Monsigny. Monoclonal antibodies (IgM) against a murine carcinoma, Lewis lung carcinoma (3LL): production, purification and in vitro selectivity.. Immunology Letters, 1984, 8 (3), pp.131-136. ⟨10.1016/0165-2478(84)90065-8⟩. ⟨hal-02163712⟩
  • Annie Claude Roche, P Bailly, Patrick Midoux, M. Monsigny. Selective macrophage activation by muramyldipeptide bound to monoclonal antibodies specific for mouse tumor cells.. Cancer Immunology, Immunotherapy, 1984, 18 (3), pp.155-159. ⟨hal-02163604⟩
  • Patrick Midoux, Philippe Wahl, Jean-Claude Auchet, Michel Monsigny. Fluorescence quenching of tryptophan by trifluoroacetamide. Biochimica et Biophysica Acta (BBA) - General Subjects, 1984, 801 (1), pp.16-25. ⟨10.1016/0304-4165(84)90207-1⟩. ⟨hal-02163704⟩
  • Patrick Midoux, Thierry Maillet, Fabienne Therain, Michel Monsigny, Annie-Claude Roche. Tumor localization of Lewis lung carcinoma with radiolabeled monoclonal antibodies. Cancer Immunology, Immunotherapy, 1984, 18 (1), pp.19-23. ⟨10.1007/BF00205394⟩. ⟨hal-02163698⟩
  • P. Midoux, J.P Grivet, F. Delmotte, M. Monsigny. The binding of monosaccharides to wheat germ agglutinin: Fluorescence and NMR investigations. Biochemical and Biophysical Research Communications, 1984, 119 (2), pp.603-611. ⟨10.1016/s0006-291x(84)80292-2⟩. ⟨hal-02163716⟩
  • M. Monsigny, Annie-Claude Roche, P. Midoux. Uptake of neoglycoproteins via membrane lectin(s) of L1210 cells evidenced by quantitative flow cytofluorometry and drug targeting.. Biology of the Cell, 1984, 51 (2), pp.187-196. ⟨10.1111/j.1768-322X.1984.tb00298.x⟩. ⟨hal-02163609⟩
  • P. Midoux, F. Delmotte, J.Ph Grivet, M. Monsigny. Protein-sugar interactions: Environmental effect on the fluorescence of O-(4-methylumbelliferyl)-glycosides. Biochemical and Biophysical Research Communications, 1983, 110 (3), pp.926-933. ⟨10.1016/0006-291X(83)91051-3⟩. ⟨hal-02163727⟩
  • A.C Roche, M. Barzilay, P. Midoux, S. Junqua, N. Sharon, et al.. Sugar-specific endocytosis of glycoproteins by Lewis lung carcinoma cells. Journal of Cellular Biochemistry, 1983, 22 (3), pp.131-140. ⟨10.1002/jcb.240220302⟩. ⟨hal-02163725⟩
  • M Midoux, J.-Ph. Grivet, M. Monsigny, P. Midoux. Lectin-sugar interactions: the binding of 1- O -methyl-di- N -trifluoroacetyl-β-chitobioside to wheat germ agglutinin. FEBS Letters, 1980, 120 (1), pp.29-32. ⟨10.1016/0014-5793(80)81038-6⟩. ⟨hal-02163732⟩

Communication dans un congrès6 documents

  • C Delehedde, G Haifei, C Gonçalves, Virginie Malard, N Rameix, et al.. Influence of the charge of mRNA mannosylated lipopolyplexes on the binding and uptake by dendritic cells. 33e colloque Biotechnocentre, Oct 2021, Seillac, France. ⟨hal-03668427⟩
  • N Laroui, C Delehedde, C Goncalves, F Godin, Federico Perche, et al.. High Efficiency of Histidylated-based Lipid Formulations for mRNA Transfection of Human Schwann Cells. SFNano 2021, Dec 2021, Angers, France. ⟨hal-03668422⟩
  • Simona Manta, Anthony Delalande, Gilles Renault, Michel Francis Bureau, Matthias Lebertre, et al.. Positively charged microbubbles to target nucleic acid delivery with ultrasound. Journées RITS 2015, Mar 2015, Dourdan, France. ⟨inserm-01154976⟩
  • Anthony Delalande, Spiros Kotopoulis, Patrick Midoux, Michiel Postema, Chantal Pichon. Ultrasound and microbubble-assisted gene delivery: insights for intracellular mechanism. Micro-acoustics in marine and medical research: 1st workshop, Dec 2011, Bergen, Norway. pp.119-130, ⟨10.5281/zenodo.4779438⟩. ⟨hal-03197797v2⟩
  • Anthony Delalande, Patrick Midoux, Chantal Pichon, Spiros Kotopoulis, Michiel Postema. Investigations of microbubble-cell interactions during the sonoporation process. 18th International Congress on Sound and Vibration, Rio de Janeiro, Brazil, 10-14 July 2011, Jul 2011, Rio de Janeiro, Brazil. ⟨hal-03195597⟩
  • Anthony Delalande, Ayache Bouakaz, Patrick Midoux, Michiel Postema, Chantal Pichon. Ultrasound-activated microbubbles for tendon gene transfer: in vivo efficiency and confocal microscopy real time intracellular investigations. 20th International Congress on Acoustics, ICA 2010, Aug 2010, Sydney, Australia. pp.524. ⟨hal-03195559⟩

Poster5 documents

  • N Laroui, C Delehedde, Cristine Gonçalves, F Godin, F Perche, et al.. High Efficiency of Histidylated-based Lipid Formulations for mRNA Transfection of Human Schwann Cells. 10th mRNA Health Conference, Nov 2021, Berlin, Germany. ⟨hal-03668434⟩
  • C Delehedde, G Haifei, Cristine Gonçalves, Virginie Malard, N Rameix, et al.. Influence of the charge of mRNA mannosylated lipopolyplexes on the binding and uptake by dendritic cells. 33e colloque Biotechnocentre, Oct 2021, Seillac, France. ⟨hal-03668442⟩
  • C Delehedde, H Gao, Cristine Gonçalves, V. Malard, N Rameix, et al.. Influence of the charge if mRNA-mannosylated lipopolyplexes on the binding and the uptake of dendritic cells. mRNA Health Conference 2020, Nov 2020, Boston (Virtual), United States. ⟨hal-03668576⟩
  • L. Pigeon, I. Pavloska, Cristine Gonçalves, Patrick Midoux, Chantal Pichon. Intracellular routing of mRNA lipoplexes in dendritic cells. ASGCT 2017, May 2017, Washington, United States. ⟨hal-03680369⟩
  • I. Pavloska, Cristine Gonçalves, Patrick Midoux, Chantal Pichon. Intracellular routing of mRNA lipoplexes in dendritic cells.. Studium Conférence, Mar 2017, Orléans, France. ⟨hal-03668580⟩

Chapitre d'ouvrage10 documents

  • Chantal Pichon, Patrick Midoux. Mannosylated and Histidylated LPR Technology for Vaccination with Tumor Antigen mRNA. Synthetic Messenger RNA and Cell Metabolism Modulation, pp.247-274, 2013, ⟨10.1007/978-1-62703-260-5_16⟩. ⟨hal-02070913⟩
  • P. Midoux, E. Lecam, D. Coulaud, E. Delain, C. Pichon. Histidine containing peptides and polypeptides as nucleic acid vectors. Luo D., Saltzman W.M. Synthetic DNA Delivery Systems, Kluwer Academic/Plenum Publishers, New-York, pp.23-44, 2003. ⟨hal-00115810⟩
  • M. Monsigny, C. Quétard, E. Duverger, C. Pichon, V. Altemayer, et al.. Glycoconjugates as vectors for gene and oligonucleotide delivery. Aubery M. Glycans in cellular interaction and recognition: therapeutic, Harwood Academic Publishers, Amsterdam, pp.193-215, 2002. ⟨hal-00115807⟩
  • P. Midoux, C. Pichon. Histidylated polycationic molecules for nucleic acids transfer. Pandalai S.G. Recent research developments in bioconjugate chemistry, Transworld Research Network, Trivandrum, pp.95-111, 2002. ⟨hal-00115805⟩
  • P. Midoux, C. Pichon. Peptide-based gene delivery systems. Mahato R.I., Kim S.W. Pharmaceutical perspectives of nucleic acid-based, Taylor & Francis, London and New York, pp.334-366, 2002. ⟨hal-00115804⟩
  • M. Monsigny, A.-C. Roche, P. Midoux, R. Mayer. Sugar Specific Delivery of Drugs, Oligonucleotides and Genes. Targeting of drugs4, Springer US, pp.31-50, 1994, 978-1-4899-1209-1. ⟨hal-02163778⟩
  • P. Midoux, A.C Roche, M. Monsigny. Endocytosis Analysis by Flow Cytometry : Study of the Endocytosis of Fluoresceinylated Neoglycoproteins Via Membrane Lectins of Macrophages. Flow cytometry NATO ASI Series, 67, Springer Berlin Heidelberg, pp.49-64, 1993. ⟨hal-02163788⟩
  • Michel Monsigny, Annie-Claude Roche, Roger Mayer, Patrick Midoux, Eric Negre, et al.. Glycosylated Polymers as Carriers for Targeting Antiviral and Antiparasite Drugs. Endocytosis - NATO ASI Series, 62, Springer Berlin Heidelberg, pp.489-496, 1992. ⟨hal-02163791⟩
  • M. Monsigny, A.C Roche, C. Kieda, R. Mayer, P. Midoux. Peptide and Carbohydrate Moieties as Molecular Signals in Animal Cell Recognition. Cell to Cell Signals in Plant, Animal and Microbial Symbiosis, Springer Berlin Heidelberg, pp.237-254, 1988. ⟨hal-02163831⟩
  • J.-Ph Grivet, P. Midoux, P. Gatellier, F. Delmotte, M. Monsigny. Wheat Germ Agglutinin: A Review of Recent Results. Structure, Dynamics, Interactions and Evolution of Biological Macromolecules, Springer Netherlands, pp.329-349, 1983. ⟨hal-02163840⟩

Brevet1 document

  • Jean-Marc Malinge, Patrick Midoux, Thomas Thibault, Chantal Pichon. In vitro production of DNA minicircles less than 250 base pairs. France, Patent n° : EP2735614A1. 2014. ⟨hal-02134791⟩

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