GUÉRIN Martine

email : martine.guerin[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.56.29

Lecturer within the thematic group DNA repair: structure, fonction and dynamic

 



26 documents

Article dans une revue

  • Charlotte Rieux, Stéphane Goffinont, Franck Coste, Zahira Tber, Julien Cros, et al.. Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights. International Journal of Molecular Sciences, MDPI, 2020, 21 (6), pp.2058. ⟨10.3390/ijms21062058⟩. ⟨hal-02904772⟩
  • R. Le Meur, Françoise Culard, V. Nadan, S. Goffinont, F. Coste, et al.. The nucleoid-associated protein HU enhances 8-oxoguanine base excision by the formamidopyrimidine-DNA glycosylase. Biochemical Journal, Portland Press, 2015, 471 (1), pp.13-23. ⟨10.1042/BJ20150387⟩. ⟨hal-01216639⟩
  • A. Biela, F. Coste, F. Culard, M. Guerin, S. Goffinont, et al.. Zinc finger oxidation of Fpg/Nei DNA glycosylases by 2-thioxanthine: biochemical and X-ray structural characterization. Nucleic Acids Research, Oxford University Press, 2014, 42 (16), pp.doi: 10.1093/nar/gku613. ⟨10.1093/nar/gku613⟩. ⟨hal-01175522⟩
  • M. Picard, S. Morisset, J.F. Cloix, J.C. Bizot, M. Guerin, et al.. Pharmacological, neurochemical, and behavioral profile of JB-788, a new 5-HT1A agonist. Neuroscience, Elsevier - International Brain Research Organization, 2010, 169 (3), pp.1337-1346. ⟨10.1016/j.neuroscience.2010.05.040⟩. ⟨hal-02071835⟩
  • Matthieu Fisichella, Hinda Dabboue, Sanjib Bhattacharyya, Gerald Lelong, Marie-Louise Saboungi, et al.. Uptake of Functionalized Mesoporous Silica Nanoparticles by Human Cancer Cells. Journal of Nanoscience and Nanotechnology, American Scientific Publishers, 2010, 10 (4), pp.314-2324. ⟨10.1166/jnn.2010.1917⟩. ⟨hal-00529333⟩
  • Matthieu Fisichella, Hinda Dabboue, Sanjib Bhattacharyya, Marie-Louise Saboungi, Jean-Paul Salvetat, et al.. Mesoporous silica nanoparticles enhance MTT formazan exocytosis in HeLa cells and astrocytes. Toxicology in Vitro, Elsevier, 2009, 23 (4), pp.697-703. ⟨10.1016/j.tiv.2009.02.007⟩. ⟨hal-02127511⟩
  • F. ToulmÉ, M Guérin, N. Robichon, M. Leng, A. Rachid Rahmouni. In vivo evidence for back and forth oscillations of the transcription elongation complex. EMBO Journal, EMBO Press, 1999, 18 (18), pp.5052-5060. ⟨10.1093/emboj/18.18.5052⟩. ⟨hal-02127238⟩
  • Laurence Pirault-Roy, L Pirault, M Guerin, F Maire, P. Marecot, et al.. Catalytic activity and EXAFS characterisation of three way automative Pt–Rh/Al2O3–CeO2 catalysts from different preparations. Applied Catalysis A: General, 1998, 172 (2), pp.249-258. ⟨10.1016/S0926-860X(98)00131-8⟩. ⟨hal-02497164⟩
  • N. Figueroa-Bossi, M Guérin, A. Rachid Rahmouni, M Leng, L Bossi. The supercoiling sensitivity of a bacterial tRNA promoter parallels its responsiveness to stringent control. EMBO Journal, EMBO Press, 1998, 17 (8), pp.2359-2367. ⟨10.1093/emboj/17.8.2359⟩. ⟨hal-02127234⟩
  • M Guerin, N. Robichon, J. Geiselmann, A. Rachid Rahmouni. A simple polypyrimidine repeat acts as an artificial Rho-dependent terminator in vivo and in vitro. Nucleic Acids Research, Oxford University Press, 1998, 26 (21), pp.4895-4900. ⟨10.1093/nar/26.21.4895⟩. ⟨hal-02127232⟩
  • Marc Boudvillain, Martine Guerin, Rozenn Dalbiès, Tula Saison-Behmoaras, Marc Leng. Transplatin-Modified Oligo(2‘- O -methyl ribonucleotide)s: A New Tool for Selective Modulation of Gene Expression †. Biochemistry, American Chemical Society, 1997, 36 (10), pp.2925 - 2931. ⟨10.1021/bi962695f⟩. ⟨hal-01880625⟩
  • M Guérin, M. Leng, A. Rachid Rahmouni. High resolution mapping of E.coli transcription elongation complex in situ reveals protein interactions with the non-transcribed strand.. EMBO Journal, EMBO Press, 1996, 15 (19), pp.5397-5407. ⟨hal-02127225⟩
  • G. Gillet, M. Guerin, A. Trembleau, G. Brun. A Bcl-2-related gene is activated in avian cells transformed by the Rous sarcoma virus.. EMBO Journal, EMBO Press, 1995, 14, pp.1372-1381. ⟨hal-00314336⟩
  • S Prost, Mg Lê, S Douc-Rasy, Jc Ahomadegbe, M Spielmann, et al.. Association of c-erbB2-gene amplification with poor prognosis in non-inflammatory breast carcinomas but not in carcinomas of the inflammatory type.. International Journal of Cancer, Wiley, 1994, 58 (6), pp.763-8. ⟨hal-02127521⟩
  • G. Gillet, D. Michel, P. Crisanti, M. Guerin, Y. Herault, et al.. Serum factors and v-src control two complementary mitogenic pathways in quail neuroretinal cells in culture.. Oncogene, Nature Publishing Group, 1993, 8, pp.565-574. ⟨hal-00314337⟩
  • S. Prost, Mg Lê, S Douc-Rasy, M Gabillot, M Guérin, et al.. C-erbB2 gene amplification, an independent prognostic indicator in node-positive and node-negative breast cancers. European Journal of Cancer, Elsevier, 1993, 29 (supplément 6), pp.S58. ⟨10.1016/0959-8049(93)90915-3⟩. ⟨hal-02127573⟩
  • Martine Guerin, Z. Sheng, N Andrieu, G Riou. Strong association between c-myb and oestrogen-receptor expression in human breast cancer.. Oncogene, Nature Publishing Group, 1990, 5 (1), pp.131-5. ⟨hal-02127528⟩
  • Martine Guerin, M Gabillot, M. Mathieu, J Travagli, M Spielmann, et al.. Structure and expression of c-erbB-2 and EGF receptor genes in inflammatory and non-inflammatory breast cancer: prognostic significance.. International Journal of Cancer, Wiley, 1989, 43 (2), pp.201-8. ⟨hal-02127536⟩
  • Martine Guerin, M. Barrois, M. Terrier, M Spielmann, G Riou. Overexpression of either c-myc or c-erbB-2/neu proto-oncogenes in human breast carcinomas: correlation with poor prognosis.. oncogene Research, 1988, 3 (1), pp.21-31. ⟨hal-02127547⟩
  • Z.M Sheng, Martine Guerin, M Gabillot, M Spielmann, G Riou. c-Ha-ras-1 polymorphism in human breast carcinomas: evidence for a normal distribution of alleles.. oncogene Research, 1988, 2 (3), pp.245-50. ⟨hal-02127541⟩
  • Martine Guerin, M. Barrois, G Riou. The expression of c-myb is strongly associated with the presence of estrogen and progesterone receptors in breast cancer. Comptes rendus de l’Académie des sciences. Série III, Sciences de la vie, Elsevier, 1988, 307 (20), pp.855-61. ⟨hal-02127559⟩
  • Martine Guerin, M.J Lacombe, G Riou. Analysis of the expression of the oncogene c-myc in human breast adenocarcinoma. Comptes rendus de l’Académie des sciences. Série III, Sciences de la vie, Elsevier, 1985, 301 (20), pp.833-8. ⟨hal-02127562⟩

Communication dans un congrès

  • J. Cros, F. Coste, S. Goffinont, Virginie Nadan, V. Roy, et al.. Discovery and characterization of inhibitors of the DNA repair enzymes hNEIL1 and hOGG1, pertinent therapeutic targets for cancer therapy. Laboratoire International Associé, Jun 2019, Varsovie, Poland. ⟨hal-02903108⟩

Poster

  • J. Cros, F. Coste, S. Goffinont, V. Gaudon, V. Roy, et al.. Search for small molecule inhibitors of the DNA repair enzymes hNEIL1 and hOGG1, potential therapeutic targets in cancer. 13th French 3R meeting, May 2019, Presqu’île de Giens, France. ⟨hal-02903219⟩
  • J. Cros, F. Coste, S. Goffinont, V. Gaudon, V. Roy, et al.. Search for small molecule inhibitors of the DNA repair enzymes hNEIL1 and hOGG1, potential therapeutic targets in cancer. Journée Fédération de recherche “Physique et Chimie du Vivant” FR2708 (CBM/ICOA), Apr 2019, Orléans, France. ⟨hal-02903223⟩

Ouvrage (y compris édition critique et traduction)

  • Kadija Essalhi, L. Gellon, Julie Berthault, Françoise Culard, Martine Guerin, et al.. Ogg1, a Saccharomyces cerevisiae bifunctional DNA glycosylase involved in base excision repair of oxidative DNA damage, interacts with the replicative DNA polymerase, Pol epsilon. pp.409, 2011. ⟨hal-00614891⟩

GARNIER Norbert

email : norbert.garnier[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.76.68

Lecturer within the thematic group DNA repair: structure, fonction and dynamic

 



49 documents

Article dans une revue

  • Charlotte Rieux, Stéphane Goffinont, Franck Coste, Zahira Tber, Julien Cros, et al.. Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights. International Journal of Molecular Sciences, MDPI, 2020, 21 (6), pp.2058. ⟨10.3390/ijms21062058⟩. ⟨hal-02904772⟩
  • Abdennour Braka, Norbert Garnier, Pascal Bonnet, Samia Aci-Seche. Residence Time Prediction of Type 1 and 2 Kinase Inhibitors from Unbinding Simulations. Journal of Chemical Information and Modeling, American Chemical Society, 2019, 60 (1), pp.342-348. ⟨10.1021/acs.jcim.9b00497⟩. ⟨hal-02494409⟩
  • Laurent Jacob, Paul Sawma, Norbert Garnier, Lionel A.T. Meyer, Justine Fritz, et al.. Inhibition of PlexA1-mediated brain tumor growth and tumor-associated angiogenesis using a transmembrane domain targeting peptide. Oncotarget, Impact journals, 2016, ⟨10.18632/oncotarget.11072⟩. ⟨hal-01407022⟩
  • Widade Ziani, Antoine-P Maillard, Isabelle Petit-Härtlein, Norbert Garnier, Serge Crouzy, et al.. The X-ray structure of NccX from Cupriavidus metallidurans 31A illustrates potential dangers of detergent solubilization when generating and interpreting crystal structures of membrane proteins.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2014, 289 (45), pp.31160-31172. ⟨10.1074/jbc.M114.586537⟩. ⟨hal-01109416⟩
  • Alexia Arpel, Paul Sawma, Caroline Spenlé, Justine Fritz, Lionel Meyer, et al.. Transmembrane Domain Targeting Peptide Antagonizing ErbB2/Neu Inhibits Breast Tumor Growth and Metastasis.. Cell Reports, Elsevier Inc, 2014, 8 (6), pp.1714-1721. ⟨10.1016/j.celrep.2014.07.044⟩. ⟨hal-01071710⟩
  • Samia Aci-Sèche, Paul Sawma, Pierre Hubert, James N. Sturgis, Dominique Bagnard, et al.. Transmembrane Recognition of the Semaphorin Co-Receptors Neuropilin 1 and Plexin A1 : Coarse-Grained Simulations. PLoS ONE, Public Library of Science, 2014, 9 (5), pp.e97779. ⟨10.1371/journal.pone.0097779⟩. ⟨hal-01175479⟩
  • Violette Senille, Dominique Lelievre, Françoise Paquet, Norbert Garnier, Ned Lamb, et al.. The addressing fragment of mitogaligin: first insights into functional and structural properties.. ChemBioChem, Wiley-VCH Verlag, 2013, 14 (6), pp.711-20. ⟨10.1002/cbic.201200715⟩. ⟨hal-00817503⟩
  • Samia Aci-Seche, Monique Genest, Norbert Garnier. Ligand entry pathways in the ligand binding domain of PPAR gamma receptor. FEBS Letters, Wiley, 2011, 585 (16), pp.2599-2603. ⟨10.1016/j.febslet.2011.07.014⟩. ⟨hal-00624897⟩
  • Norbert Garnier, Karine Loth, Franck Coste, Rafal Augustyniak, Virginie Nadan, et al.. An alternative flexible conformation of the E. coli HU beta(2) protein: structural, dynamics, and functional aspects. European Biophysics Journal, Springer Verlag (Germany), 2011, 40 (2), pp.117-129. ⟨10.1007/s00249-010-0630-y⟩. ⟨hal-00602370⟩
  • Samia Aci-Sèche, Norbert Garnier, Stéphane Goffinont, Daniel Genest, Spotheim-Maurizot Mélanie, et al.. Comparing native and irradiated E. coli lactose repressor-operator complex by molecular dynamics simulation. European Biophysics Journal, Springer Verlag (Germany), 2010, 39 (10), pp.1375-1384. ⟨10.1007/s00249-010-0591-1⟩. ⟨hal-00529210⟩
  • Samia Aci-Seche, Norbert Garnier, Daniel Genest, Stéphane Bourg, Christophe Marot, et al.. Molecular Dynamics Empirical Approach for Generating a Small Set of Structures Representative of the Internal Flexibility of a Receptor. QSAR & Combinatorial Science, 2009, 28 (9), pp.959-968. ⟨hal-00521647⟩
  • Samia Aci-Seche, Norbert Garnier, Daniel Genest, Stéphane Bourg, Christophe Marot, et al.. A Restrained Molecular Dynamics Empirical Approach for Generating a Small Set of Structures Representative of the Internal Flexibility of a Receptor. QSAR & Combinatorial Science, 2009, 28 (9), pp.959-968. ⟨10.1002/qsar.200910031⟩. ⟨hal-02904717⟩
  • Oumarou Samna Soumana, Norbert Garnier, Monique Genest. Insight into the recognition patterns of the ErbB receptor family transmembrane domains: heterodimerization models through MD search. European Biophysics Journal, Springer Verlag (Germany), 2008, 37 (6), pp.851-864. ⟨10.1007/s00249-008-0293-0⟩. ⟨hal-00284330⟩
  • Daniel Genest, Norbert Garnier, Alban Arrault, Christophe Marot, Luc Morin-Allory, et al.. Ligand-escape pathways from the ligand-binding domain of PPAR gamma receptor as probed by molecular dynamics simulations. European Biophysics Journal, Springer Verlag (Germany), 2008, 37, pp.369-379. ⟨10.1007/s00249-007-0220-9⟩. ⟨hal-00512476⟩
  • Oumarou Samna Soumana, Norbert Garnier, Monique Genest. Molecular dynamics simulation approach for the prediction of transmembrane helix–helix heterodimers assembly. European Biophysics Journal, Springer Verlag (Germany), 2007, 36 (8), pp.1071-1082. ⟨10.1021/jm0702175 S0022-2623(07)00217-8⟩. ⟨hal-00166544⟩
  • Pierre Aller, Norbert Garnier, Monique Genest. Transmembrane Helix Packing of ErbB/Neu Receptor in Membrane Environment: A Molecular Dynamics Study. Journal of biomolecular structure & dynamics, 2006, 24 (3), pp.209-228. ⟨hal-00111939⟩
  • O. Samna Soumana, P. Aller, Norbert Garnier, M. Genest. Transmembrane peptides from tyrosine kinase receptor. Mutation-related behavior in a lipid bilayer investigated by molecular dynamics simulations. Journal of biomolecular structure & dynamics, 2005, 23, pp.91-100. ⟨hal-00088672⟩
  • P. Aller, L. Voiry, Norbert Garnier, M. Genest. Molecular dynamics (MD) investigations of preformed structures of the transmembrane domain of the oncogenic Neu receptor dimer in a DMPC bilayer. Biopolymers, Wiley, 2005, 77, pp.184-197. ⟨hal-00088475⟩
  • Norbert Garnier, Serge Crouzy, Monique Genest. Molecular Dynamics Simulations of the Transmembrane Domain of the Oncogenic ErbB2 Receptor Dimer in a DMPC Bilayer. Journal of Biomolecular Structure and Dynamics, Taylor & Francis: STM, Behavioural Science and Public Health Titles, 2003, 21 (2), pp.179-200. ⟨10.1080/07391102.2003.10506916⟩. ⟨hal-02123803⟩
  • J-P Duneau, S. Crouzy, Norbert Garnier, Y. Chapron, M Genest. Molecular dynamics simulations of the ErbB-2 transmembrane domain within an explicit membrane environment: comparison with vacuum simulations.. Biophysical Chemistry, Elsevier, 1999, 76 (1), pp.35-53. ⟨hal-02123801⟩
  • Nicolas Sajot, Norbert Garnier, Monique Genest. Dimer models for ErbB-2/neu transmembrane domains from molecular dynamics simulations. Theoretical Chemistry Accounts: Theory, Computation, and Modeling, Springer Verlag, 1999, 101 (1-3), pp.67-72. ⟨10.1007/s002140050408⟩. ⟨hal-02123800⟩
  • J-P Duneau, Norbert Garnier, G Cremel, G Nullans, P. Hubert, et al.. Time resolved fluorescence properties of phenylalanine in different environments. Comparison with molecular dynamics simulation.. Biophysical Chemistry, Elsevier, 1998, 73 (1-2), pp.109-19. ⟨hal-02123796⟩
  • Jean-Pierre Duneau, Norbert Garnier, Monique Genest. Insight into Signal Transduction: Structural Alterations in Transmembrane Helices Probed by Multi-1 ns Molecular Dynamics Simulations. Journal of Biomolecular Structure and Dynamics, Taylor & Francis: STM, Behavioural Science and Public Health Titles, 1997, 15 (3), pp.555-572. ⟨10.1080/07391102.1997.10508966⟩. ⟨hal-02123789⟩
  • Norbert Garnier, Daniel Genest, Jean Pierre Duneau, Monique Genest. Molecular modeling of c-erbB2 receptor dimerization: Coiled-coil structure of wild and oncogenic transmembrane domains—Stabilization by interhelical hydrogen bonds in the oncogenic form. Biopolymers, Wiley, 1997, 42 (2), pp.157-168. 3.0.CO;2-M">⟨10.1002/(SICI)1097-0282(199708)42:2<157::AID-BIP5>3.0.CO;2-M⟩. ⟨hal-02123792⟩
  • Norbert Garnier, D. Genest, M Genest. Correlated motions and propagation of the effect of a local conformational change in the transmembrane helix of the c-erb B2 encoded protein and its V659E mutant, studied by molecular dynamics simulations.. Biophysical Chemistry, Elsevier, 1996, 58 (3), pp.225-37. ⟨hal-02123788⟩
  • Norbert Garnier, Daniel Genest, Eric Hebert, Monique Genest. Influence of a Mutation in the Transmembrane Domain of the pl85 c- erb B2 Oncogene-Encoded Protein Studied by Molecular Dynamics Simulations. Journal of Biomolecular Structure and Dynamics, Taylor & Francis: STM, Behavioural Science and Public Health Titles, 1994, 11 (5), pp.983-1002. ⟨10.1080/07391102.1994.10508047⟩. ⟨hal-02123785⟩
  • Norbert Garnier, N. Ostrowsky. Brownian dynamics in a confined geometry. Experiments and numerical simulations. Journal de Physique II, EDP Sciences, 1991, 1 (10), pp.1221-1232. ⟨10.1051/jp2:1991129⟩. ⟨jpa-00247585⟩
  • N Ostrowsky, Norbert Garnier. Quasi-elastic light scattering from an evanescent wave to probe particle/wall interactions.. Biochemical Society Transactions, Portland Press, 1991, 19 (2), pp.500-1. ⟨hal-02123775⟩
  • Nicole Ostrowsky, Norbert Garnier, Didier Sornette. THE USE OF DYNAMIC LIGHT SCATTERING IN STUDIES OF VESICLES INTERACTIONS. Journal of Dispersion Science and Technology, Taylor & Francis, 1989, 10 (3), pp.277-284. ⟨10.1080/01932698908943176⟩. ⟨hal-02123769⟩

Communication dans un congrès

  • A. Wacquiez, F. Coste, V. Nadan, E. Kut, Norbert Garnier, et al.. Interaction de la protéine NS1 avec l’ARN : mécanismes impliqués dans la reconnaissance spécifique. Colloque annuel de ResaFlu, Réseau français sur les virus Influenza, Mar 2019, Lyon, France. ⟨hal-02903093⟩
  • Justine Largillière, Rémy Le Meur, David Guiguène, Norbert Garnier, Celine Landon, et al.. Vers une description cinétique et structurale complète du mécanisme d'échange de chaînes de la protéine HU d'Escherichia coli.. GERM 2019, May 2019, Oléron, France. ⟨hal-02361645⟩
  • J. Cros, F. Coste, S. Goffinont, Virginie Nadan, V. Roy, et al.. Discovery and characterization of inhibitors of the DNA repair enzymes hNEIL1 and hOGG1, pertinent therapeutic targets for cancer therapy. Laboratoire International Associé, Jun 2019, Varsovie, Poland. ⟨hal-02903108⟩
  • A. Braka, S. Aci-Sèche, Bourg Stéphane, Norbert Garnier, P. Bonnet. Impact and prediction of binding kinetics on in vivo drug efficacy. 5th EFMC Young Medical Chemist Symposium, Sep 2018, Ljubljana, Slovenia. ⟨hal-02903060⟩

Poster

  • Justine Largillière, Rémy Le Meur, David Guinguène, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system.. NMR : a tool for biology XITh, Jan 2019, Paris, France. ⟨hal-02362588⟩
  • Justine Largillière, Rémy Le Meur, David Guinguène, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system.. Journée Fédération de recherche “Physique et Chimie du Vivant”, Apr 2019, Orléans, France. ⟨hal-02362578⟩
  • J. Cros, F. Coste, S. Goffinont, V. Gaudon, V. Roy, et al.. Search for small molecule inhibitors of the DNA repair enzymes hNEIL1 and hOGG1, potential therapeutic targets in cancer. 13th French 3R meeting, May 2019, Presqu’île de Giens, France. ⟨hal-02903219⟩
  • J. Cros, F. Coste, S. Goffinont, V. Gaudon, V. Roy, et al.. Search for small molecule inhibitors of the DNA repair enzymes hNEIL1 and hOGG1, potential therapeutic targets in cancer. Journée Fédération de recherche “Physique et Chimie du Vivant” FR2708 (CBM/ICOA), Apr 2019, Orléans, France. ⟨hal-02903223⟩
  • Justine Largillière, Rémy Le Meur, David Guinguène, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system.. 31e colloque Biotechnocentre, Oct 2018, Seillac, France. ⟨hal-02362818⟩
  • Justine Largillière, Rémy Le Meur, Norbert Garnier, Celine Landon, A.F. Delmas, et al.. Native and Intermediate conformations of the three HU dimers of E.coli.. XXVIII ICMRBS 2018, Aug 2018, Dublin, Ireland. ⟨hal-02362585⟩
  • A. Braka, S. Aci-Sèche, S. Bourg, Norbert Garnier, P. Bonnet. LIM kinase inhibitors discovery by flexible protein high-throughput virtual screening. Structure-based design of LIM kinase inhibitors. Journée Fédération de recherche “Physique et Chimie du Vivant” FR2708 (CBM/ICOA), Jan 2018, Orléans, France. ⟨hal-02904708⟩
  • A. Braka, S. Aci-Sèche, S. Bourg, Norbert Garnier, P. Bonnet. Path-based simulation of ligand-receptor binding process for binding kinetics prediction. XXIVe Journées Jeunes Chercheurs (SCT), Feb 2017, Châtenay-Malabry, France. ⟨hal-02904830⟩
  • A. Braka, S. Aci-Sèche, S. Bourg, Norbert Garnier, P. Bonnet. Simulation of the protein-ligand association process for kinetics prediction. 20e congrès du Groupe de Graphisme et Modélisation Moléculaire (GGMM), May 2017, Reims, France. ⟨hal-02904825⟩
  • A. Champiré, A. Braka, Béatrice Vallée, M. Doudeau, F. Godin, et al.. Design, synthesis and biological evaluation of LIMK inhibitors. XXIVe Journées Jeunes Chercheurs (SCT), Feb 2017, Châtenay-Malabry, France. ⟨hal-02904837⟩
  • A. Champiré, A. Braka, B. VallÉe, M. Doudeau, F. Godin, et al.. LIM kinases as new therapeutic targets for the treatment of neurofibromatosis type 1. VII International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC) –, Aug 2017, Vienne, Austria. ⟨hal-02904794⟩
  • A. Braka, S. Aci-Sèche, Norbert Garnier, S. Bourg, P. Bonnet. Kinetic rates prediction of protein kinase inhibitors by enhanced molecular dynamics. K4DD Meeting - Binding kinetics: Time is of the essence, Nov 2017, Berlin, Germany. ⟨hal-02904780⟩
  • A. Braka, S. Aci-Sèche, S. Bourg, Norbert Garnier, P. Bonnet. Etude par simulations de dynamique moléculaire de la cinétique du processus d’association récepteur-ligand. 29e colloque de Biotechnocentre, Oct 2016, Seillac, France. ⟨hal-02904842⟩
  • A. Champiré, A. Braka, Béatrice Vallée, M. Doudeau, F. Godin, et al.. Conception, synthèse et évaluation biologique d’inhibiteurs de LIM kinases. 29e colloque de Biotechnocentre, Oct 2016, Seillac, France. ⟨hal-02904847⟩

Chapitre d'ouvrage

  • Norbert Garnier, D. Genest, M. Genest. Motions and correlations of the transmembrane domain of a protein receptor studied by molecular dynamics simulation. Nonlinear excitations in biomolecules, Springer Berlin Heidelberg, pp.241-246, 1994. ⟨hal-02123780⟩
  • N. Ostrowsky, Norbert Garnier. Brownian dynamics close to a wall, measured by quasi-elastic light scattering from an evanescent wave. Progress in colloid and polymer science, 84, Steinkopff, Heildberg, pp.371-376, 1991, Progress in Colloid & Polymer Science. ⟨hal-02123777⟩

GABANT Guillaume

email : guillaume.gabant[remplacer_par_at]cnrs-orleans.fr

Phone : 02.38.25.54.57

Engineer in chemical analysis within the thematic group Functional Mass Spectrometry in Metastasis and technical responsible of the facility for mass spectrometry and proteomics

 



23 documents

Article dans une revue

  • Koffi N’guessan, Renata Grzywa, Seda Seren, Guillaume Gabant, Maria Juliano, et al.. Human proteinase 3 resistance to inhibition extends to alpha‐2 macroglobulin. FEBS Journal, Wiley, 2020, ⟨10.1111/febs.15229⟩. ⟨hal-02901768⟩
  • Francisco Rodrigues, Thomas Georgelin, Guillaume Gabant, Baptiste Rigaud, Fabrice Gaslain, et al.. Confinement and Time Immemorial: Prebiotic Synthesis of Nucleotides on a Porous Mineral Nanoreactor. Journal of Physical Chemistry Letters, American Chemical Society, 2019, 10 (15), pp.4192-4196. ⟨10.1021/acs.jpclett.9b01448⟩. ⟨hal-02308428⟩
  • Artur Castro-Rodrigues, Yaxian Zhao, Fátima Fonseca, Guillaume Gabant, Martine Cadène, et al.. The Interaction between the Drosophila EAG Potassium Channel and the Protein Kinase CaMKII Involves an Extensive Interface at the Active Site of the Kinase. Journal of Molecular Biology, Elsevier, 2018, 430 (24), pp.5029-5049. ⟨hal-01966024⟩
  • Guillaume Gabant, Alain Boyer, Martine Cadene. SSPaQ: A Subtractive Segmentation Approach for the Exhaustive Parallel Quantification of the Extent of Protein Modification at Every Possible Site. Journal of The American Society for Mass Spectrometry, Springer Verlag (Germany), 2016, 27 (8), pp.1328 - 1343. ⟨10.1007/s13361-016-1416-y⟩. ⟨hal-01406961⟩
  • Maria joão Marques-Carvalho, Johannes Oppermann, Eva Muñoz, Andreia s. Fernandes, Guillaume Gabant, et al.. Molecular Insights into the Mechanism of Calmodulin Inhibition of the EAG1 Potassium Channel. Structure, Elsevier (Cell Press), 2016, 24 (10), pp.1742 - 1754. ⟨10.1016/j.str.2016.07.020⟩. ⟨hal-01407944⟩
  • Nicolas Bouchet, Jerome Jaillet, Guillaume Gabant, Benjamin Brillet, Luis Briseño-Roa, et al.. cAMP protein kinase phosphorylates the Mos1 transposase and regulates its activity: evidences from mass spectrometry and biochemical analyses. Nucleic Acids Research, Oxford University Press, 2014, 42 (2), pp.1117-1128. ⟨10.1093/nar/gkt874⟩. ⟨hal-02132866⟩
  • C. Guarino, M. Legowska, C. Epinette, C. Kellenberger, S. Dallet-Choisy, et al.. New Selective Peptidyl Di(chlorophenyl) Phosphonate Esters for Visualizing and Blocking Neutrophil Proteinase 3 in Human Diseases. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2014, 289 (46), pp.doi: 10.1074/jbc.M114.591339. ⟨10.1074/jbc.M114.591339⟩. ⟨hal-01179111⟩
  • Chrystelle Derache, Christophe Epinette, Alain Roussel, Guillaume Gabant, Martine Cadene, et al.. Crystal structure of greglin, a novel non-classical Kazal inhibitor, in complex with subtilisin.. FEBS Journal, Wiley, 2012, 279 (24), pp.4466-78. ⟨10.1111/febs.12033⟩. ⟨hal-00817089⟩
  • Maria J Marques-Carvalho, Nirakar Sahoo, Frederick W Muskett, Ricardo S Vieira-Pires, Guillaume Gabant, et al.. Structural, Biochemical, and Functional Characterization of the Cyclic Nucleotide Binding Homology Domain from the Mouse EAG1 Potassium Channel.. Journal of Molecular Biology, Elsevier, 2012, 423 (1), pp.34-46. ⟨10.1016/j.jmb.2012.06.025⟩. ⟨hal-00747621⟩
  • Philippe Vergne, Marion Maene, Guillaume Gabant, Aurélie Chauvet, Thomas Debener, et al.. Somatic embryogenesis and transformation of the diploid Rosa chinensis cv Old Blush. Plant Cell, Tissue and Organ Culture, Springer Verlag, 2010, 100 (1), pp.73-78. ⟨10.1007/s11240-009-9621-z⟩. ⟨hal-00734277⟩
  • Guillaume Gabant, Martine Cadène. Mass spectrometry of full-length integral membrane proteins to define functionally relevant structural features. Methods, Elsevier, 2008, 46, pp.54-61. ⟨10.1016/j.ymeth.2008.10.021⟩. ⟨hal-00512469⟩
  • Guillaume Gabant, Julie Augier, Jean Armengaud. Assessment of solvent residues accessibility using three Sulfo-NHS-biotin reagents in parallel: application to footprint changes of a methyltransferase upon binding its substrate. Journal of Mass Spectrometry, Wiley-Blackwell, 2008, 43 (3), pp.360-370. ⟨10.1002/jms.1328⟩. ⟨hal-02132921⟩
  • Guillaume Gabant, Alain Lorphelin, Nathalie Nozerand, Charles Marchetti, Laurent Bellanger, et al.. Autophosphorylated Residues Involved in the Regulation of Human Chk2 In Vitro. Journal of Molecular Biology, Elsevier, 2008, 380 (3), pp.489-503. ⟨10.1016/j.jmb.2008.04.053⟩. ⟨hal-02132876⟩
  • Guillaume Gabant, Sylvie Auxilien, Irina Tuszynska, Marie Locard, Michal Gajda, et al.. THUMP from archaeal tRNA:m22G10 methyltransferase, a genuine autonomously folding domain. Nucleic Acids Research, Oxford University Press, 2006, 34 (9), pp.2483-2494. ⟨10.1093/nar/gkl145⟩. ⟨hal-02132929⟩

Communication dans un congrès

  • G. Gabant, A. Boyer, Y. Berteaux, Martine Cadene. SSPaQ: a new method for the quantification of modification at all possible sites of a protein. 33es Journées de la Société Française de Spectrométrie de Masse, Sep 2016, Bordeaux, France. ⟨hal-02902960⟩

Poster

  • G. Gabant, M. Nemcic, J. Pinetre, Martine Cadene. Tuning ETD Top Down MS parameters on a UHR-QTOF instrument to improve protein the fragmentation coverage. SMMAP 2019, Sep 2019, Strasbourg, France. ⟨hal-02902968⟩
  • T. Bijot, G. Gabant, Martine Cadene. Development of an original footprinting approach to localize non-covalent ligand binding sites. 30e Colloque Biotechnocentre, Oct 2017, Seillac, France. ⟨hal-02902974⟩
  • T. Bijot, G. Gabant, Martine Cadene. Towards a faster localization of noncovalent ligand binding sites using an original footprinting method. 11es Journées du Cancéropôle Grand Ouest, Jun 2017, Vannes, France. ⟨hal-02902989⟩
  • T. Bijot, G. Gabant, Martine Cadene. Towards a faster localization of noncovalent ligand binding sites using an original footprinting method. SMMAP 2017, Oct 2017, Marne-la-Vallée, France. ⟨hal-02902978⟩
  • G. Gabant, Martine Cadene. Assessing chemical labeling of proteins by mass spectrometry: MALDI−TOF to the rescue of ESI−HRMS. SMMAP 2017, Oct 2017, Marne-la-Vallée, France. ⟨hal-02902984⟩
  • G. Gabant, A. Boyer, Martine Cadene. SSPaQ: a subtractive method for the parallel quantification of the degree of modification at every possible site of a protein. 64th ASMS Conference, Jun 2016, San-Antonio, Texas, United States. ⟨hal-02903009⟩
  • G. Gabant, Y. Richer, S. Motteau, E. Mebold, Martine Cadene. Towards a prediction of protein reactivity against electrophile ligands: 1. Ranking amino acid side chain nucleophilicities. 64th ASMS Conference, Jun 2016, San Antonio, Texas, United States. ⟨hal-02903017⟩

Thèse

  • Guillaume Gabant. Spectrométrie de masse des modifications induites ou post-traductionnelles de protéines : méthodologie et application à des protéines d’intérêt thérapeutique. Biochimie, Biologie Moléculaire. Université d'Orléans, 2014. Français. ⟨NNT : 2014ORLE2061⟩. ⟨tel-01246054⟩

EVENO Eric

 

email : eric.eveno@cnrs-orleans.fr

Phone : +33 2.38.25.56.03

Research engineer in biological sciences and bioinformatic within the group “RNA Remodeling Factors & Mechanisms”



32 documents

Article dans une revue

  • Lionello Bossi, Mathilde Ratel, Camille Laurent, Patricia Kerboriou, Andrew Camilli, et al.. NusG prevents transcriptional invasion of H-NS-silenced genes. PLoS Genetics, Public Library of Science, 2019, 15 (10), pp.e1008425. ⟨10.1371/journal.pgen.1008425⟩. ⟨hal-02308418⟩
  • Morgane Salines, Marine Dumarest, Mathieu Andraud, Sophie Mahé, Elodie Barnaud, et al.. Natural viral co-infections in pig herds affect hepatitis e virus (hev) infection dynamics and increase the risk of contaminated livers at slaughter. Transboundary and emerging diseases, Wiley-Blackwell, 2019, 66 (5), pp.1930-1945. ⟨10.1111/tbed.13224⟩. ⟨hal-02617859⟩
  • Cédric Nadiras, Eric Eveno, Annie Schwartz, Nara Figueroa-Bossi, Marc Boudvillain. A multivariate prediction model for Rho-dependent termination of transcription. Nucleic Acids Research, Oxford University Press, 2018, 46 (16), pp.8245 - 8260. ⟨10.1093/nar/gky563⟩. ⟨hal-01880575⟩
  • Linda Cambier, Patrice Rassam, Béatrice Chabi, Karima Mezghenna, René Gross, et al.. M19 modulates skeletal muscle differentiation and insulin secretion in pancreatic β-cells through modulation of respiratory chain activity.. Clinical Neurology and Neurosurgery, Elsevier, 2012, 7 (2), pp.e31815. ⟨10.1371/journal.pone.0031815⟩. ⟨hal-00706794⟩
  • J. Bousquet, J. Anto, C. Auffray, M. Akdis, A. Cambon-Thomsen, et al.. MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine.. Allergy, Wiley, 2011, 66 (5), pp.596-604. ⟨10.1111/j.1398-9995.2010.02534.x⟩. ⟨hal-00595853⟩
  • Marie-Anne Debily, Sandrine El Marhomy, Virginie Boulanger, Eric Eveno, Régine Mariage-Samson, et al.. A Functional and Regulatory Network Associated with PIP Expression in Human Breast Cancer. PLoS ONE, Public Library of Science, 2009, 4 (3), pp.e4696. ⟨10.1371/journal.pone.0004696⟩. ⟨hal-02115235⟩
  • Chisato Yamasaki, Katsuhiko Murakami, Yasuyuki Fujii, Yoshiharu Sato, Erimi Harada, et al.. The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. Nucleic Acids Research, Oxford University Press, 2007, 36 (Database), pp.D793-D799. ⟨10.1093/nar/gkm999⟩. ⟨hal-02115283⟩
  • Esther Graudens, Virginie Boulanger, Cindy Mollard, Régine Mariage-Samson, Xavier Barlet, et al.. Deciphering cellular states of innate tumor drug responses. Genome Biology, BioMed Central, 2006, 7 (3), pp.R19. ⟨10.1186/gb-2006-7-3-r19⟩. ⟨hal-02115293⟩
  • Y. Du, Kankan Wang, Hai Fang, Junmin Li, Dakai Xiao, et al.. Coordination of intrinsic, extrinsic, and endoplasmic reticulum-mediated apoptosis by imatinib mesylate combined with arsenic trioxide in chronic myeloid leukemia. Blood, American Society of Hematology, 2006, 107 (4), pp.1582-1590. ⟨10.1182/blood-2005-06-2318⟩. ⟨hal-02115308⟩
  • P.-Z. Zheng, K.-K. Wang, Q.-H. Huang, Y.-Z. Du, Q.-Y. Zhang, et al.. Systems analysis of transcriptome and proteome in retinoic acid/arsenic trioxide-induced cell differentiation/apoptosis of promyelocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2005, 102 (21), pp.7653-7658. ⟨10.1073/pnas.0502825102⟩. ⟨hal-02115327⟩
  • Motohiko Tanino, Marie-Anne Debily, Takuro Tamura, Teruyoshi Hishiki, Osamu Ogasawara, et al.. The Human Anatomic Gene Expression Library (H-ANGEL), the H-Inv integrative display of human gene expression across disparate technologies and platforms. Nucleic Acids Research, Oxford University Press, 2005, 33 (Database issue), pp.D567-D572. ⟨10.1093/nar/gki104⟩. ⟨hal-02115361⟩
  • S. Imbeaud, Esther Graudens, Virginie Boulanger, Xavier Barlet, Patrick Zaborski, et al.. Towards standardization of RNA quality assessment using user-independent classifiers of microcapillary electrophoresis traces. Nucleic Acids Research, Oxford University Press, 2005, 33 (6), pp.e56-e56. ⟨10.1093/nar/gni054⟩. ⟨hal-02115318⟩
  • Sylvie Bortoli, Valérie Renault, Régine Mariage-Samson, Eric Eveno, Charles Auffray, et al.. Modifications in the myogenic program induced by in vivo and in vitro aging. Gene, Elsevier, 2005, 347 (1), pp.65-72. ⟨10.1016/j.gene.2004.12.029⟩. ⟨hal-02115339⟩
  • Lydia Riou, Eric Eveno, Anneke van Hoffen, Albert van Zeeland, Alain Sarasin, et al.. Differential Repair of the Two Major UV-Induced Photolesions in Trichothiodystrophy Fibroblasts. Cancer Research, American Association for Cancer Research, 2004, 64 (3), pp.889-894. ⟨10.1158/0008-5472.CAN-03-2070⟩. ⟨hal-02115390⟩
  • Tadashi Imanishi, Takeshi Itoh, Yutaka Suzuki, Claire O'Donovan, Satoshi Fukuchi, et al.. Integrative annotation of 21,037 human genes validated by full-length cDNA clones.. PLoS Biology, Public Library of Science, 2004, 2 (6), pp.856-875. ⟨inria-00099938⟩
  • Sylvie Bortoli, Valérie Renault, Eric Eveno, Charles Auffray, Gill Butler-Browne, et al.. Gene expression profiling of human satellite cells during muscular aging using cDNA arrays. Gene, Elsevier, 2003, 321, pp.145-154. ⟨10.1016/j.gene.2003.08.025⟩. ⟨hal-02115386⟩
  • Julien Chuquet, Karim Benchenane, Géraldine Liot, Mónica Fernández-Monreal, Jérôme Toutain, et al.. Matching Gene Expression with Hypometabolism after Cerebral Ischemia in the Nonhuman Primate. Journal of Cerebral Blood Flow and Metabolism, Nature Publishing Group, 2002, 22 (10), pp.1165-1169. ⟨10.1097/01.wcb.0000037987.07114.7c⟩. ⟨hal-02115394⟩
  • Charles Decraene, Bernard Brugg, Merle Ruberg, Eric Eveno, Christiane Matingou, et al.. Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays.. Genome Biology, BioMed Central, 2002, 3 (8), pp.RESEARCH0042. ⟨inserm-00123593⟩
  • E.N. Miyaji, R.T. Johnson, C.S. Downes, Eric Eveno, M. Mezzina, et al.. Characterization of a mutant rat kangaroo cell line with alterations in the cell cycle and DNA repair. Genetics and Molecular Biology, Sociedade Brasileira de Genética, 2000, 23 (3), pp.689-694. ⟨10.1590/S1415-47572000000300031⟩. ⟨hal-02115450⟩
  • Geneviève Pietu, Régine Mariage-Samson, Nicole Fayein, Christiane Matingou, Eric Eveno, et al.. The Genexpress IMAGE Knowledge base of human brain transcriptome : a prototype of integrated resource for functional and computational genomics. Genome Research, Cold Spring Harbor Laboratory Press, 1999, 9 (2), pp.195-209. ⟨hal-00098890⟩
  • G. Pietu, Eric Eveno, Béatrice Soury-Segurens, Nicole-Adeline Fayein, Régine Mariage-Samson, et al.. The Genexpress IMAGE Knowledge Base of the Human Muscle Transcriptome: A Resource of Structural, Functional, and Positional Candidate Genes for Muscle Physiology and Pathologies. Genome Research, Cold Spring Harbor Laboratory Press, 1999, 9 (12), pp.1313-1320. ⟨10.1101/gr.9.12.1313⟩. ⟨hal-02115457⟩
  • M Weeda, Eric Eveno, I Donker, W Vermeulen, O Chevallier-Lagente, et al.. A mutation in the XPB/ERCC3 DNA repair transcription gene, associated with trichothiodystrophy.. American Journal of Human Genetics, Elsevier (Cell Press), 1997, 60 (2), pp.320-9. ⟨hal-02115478⟩
  • L. Zeng, X Quilliet, L Chevallier-Lagente, Eric Eveno, A. Sarasin, et al.. Retrovirus-mediated gene transfer corrects DNA repair defect of xeroderma pigmentosum cells of complementation groups A, B and C. Gene Therapy, Nature Publishing Group, 1997, 4 (10), pp.1077-1084. ⟨10.1038/sj.gt.3300495⟩. ⟨hal-02115463⟩
  • Tanya Stojkovic, Luc Defebvre, Xavier Quilliet, Eric Eveno, Alain Sarasin, et al.. Neurological manifestations in two related xeroderma pigmentosum group d patients: Complications of the late-onset type of the juvenile form. Movement Disorders, Wiley, 1997, 12 (4), pp.616-619. ⟨10.1002/mds.870120428⟩. ⟨hal-02115471⟩
  • Xavier Quilliet, Odile Chevallier-Lagente, Eric Eveno, Tania Stojkovic, Alain Destée, et al.. Long-term complementation of DNA repair deficient human primary fibroblasts by retroviral transduction of the XPD gene. Mutation Research/DNA Repair, Elsevier, 1996, 364 (3), pp.161-169. ⟨10.1016/S0921-8777(96)00024-9⟩. ⟨hal-02115482⟩
  • Madeleine Carreau, Xavier Quilliet, Eric Eveno, Anna Salvetti, Olivier Danos, et al.. Functional Retroviral Vector for Gene Therapy of Xeroderma Pigmentosum Group D Patients. Human Gene Therapy, Mary Ann Liebert, 1995, 6 (10), pp.1307-1315. ⟨10.1089/hum.1995.6.10-1307⟩. ⟨hal-02115500⟩
  • Eric Eveno, X. Quilliet, O. Chevallier-Lagente, L. Daya-Grosjean, A. Stary, et al.. Stable SV40-transformation and characterisation of some DNA repair properties of fibroblasts from a trichothiodystrophy patient. Biochimie, Elsevier, 1995, 77 (11), pp.906-912. ⟨10.1016/0300-9084(95)90011-X⟩. ⟨hal-02115494⟩
  • Eric Eveno, F Bourre, X Quilliet, O Chevallier-Lagente, L Roza, et al.. Different removal of ultraviolet photoproducts in genetically related xeroderma pigmentosum and trichothiodystrophy diseases.. Cancer Research, American Association for Cancer Research, 1995, 55 (19), pp.4325-32. ⟨hal-02115488⟩
  • M Carreau, Eric Eveno, X Quilliet, O Chevalier-Lagente, A. Benoît, et al.. Development of a new easy complementation assay for DNA repair deficient human syndromes using cloned repair genes.. Carcinogenesis, Oxford University Press (OUP), 1995, 16 (5), pp.1003-9. ⟨hal-02115507⟩
  • C Mezzina, Eric Eveno, C Chevallier-Lagente, A. Benoît, C. Carreau, et al.. Correction by the ERCC2 gene of UV sensitivity and repair deficiency phenotype in a subset of trichothiodystrophy cells.. Carcinogenesis, Oxford University Press (OUP), 1994, 15 (8), pp.1493-8. ⟨hal-02115514⟩
  • J.P. Hugnot, H. Gilgenkrantz, P. Chafey, M. Lambert, Eric Eveno, et al.. Expression of the Dystrophin Gene in Cultured Fibroblasts. Biochemical and Biophysical Research Communications, Elsevier, 1993, 192 (1), pp.69-74. ⟨10.1006/bbrc.1993.1382⟩. ⟨hal-02115517⟩

Poster

  • C. Nadiras, Eric Eveno, A. Schwartz, M. Boudvillain. Analyse des terminateurs Rho-dépendants bactériens. 29e colloque Biotechnocentre, Oct 2016, Seillac, France. ⟨hal-02453368⟩

DELMAS Agnès

 

email : agnes.delmas[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.76.42

Research director, Responsible of the thematic group “NMR of biomolecules”, Director of the “Research Federation “Physics and Chemistry of the Living”

 



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