MALARD Virginie

email : virginie.malar[remplacer_par_at]@cnrs-orleans.fr

Téléphone : 02.38.25.56.23

Ingénieur d’Etudes en analyse chimique au sein de l’équipe “Protéines de synthèse et chimie bioorthogonale”

 



8 documents

Article dans une revue

  • Haifei Gao, Cristine Goncalves, Téo Gallego, Marc Francois-Heude, Virginie Malard, et al.. Comparative binding and uptake of liposomes decorated with mannose oligosaccharides by cells expressing the mannose receptor or DC-SIGN. Carbohydrate Research, 2020, 487, pp.107877. ⟨10.1016/j.carres.2019.107877⟩. ⟨hal-02522179⟩
  • Kevin van Der Jeught, Stefaan de Koker, Lukasz Bialkowski, Carlo Heirman, Patrick Tjok Joe, et al.. Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety. ACS Nano, 2018, 12 (10), pp.9815-9829. ⟨10.1021/acsnano.8b00966⟩. ⟨hal-01889829⟩
  • A. Le Moignic, V. Malard, T. Benvegnu, L. Lemiègre, Mathieu Berchel, et al.. Preclinical evaluation of mRNA trimannosylated lipopolyplexes as therapeutic cancer vaccines targeting dendritic cells. Journal of Controlled Release, 2018, 278, pp.110 - 121. ⟨10.1016/j.jconrel.2018.03.035⟩. ⟨hal-01774851⟩
  • Samuel Guillot, Fabienne Meducin, Kristina Poljak, Virginie Malard, Alexandra Foucault-Collet, et al.. Nanostructured monolinolein miniemulsions as delivery systems: Role of the internal mesophase on cytotoxicity and cell internalization. International Journal of Pharmaceutics, 2017, 523 (1), pp.142 - 150. ⟨10.1016/j.ijpharm.2017.03.012⟩. ⟨hal-01656547⟩
  • J. Barbeau, L. Lemiègre, A. Quelen, V. Malard, H. Gao, et al.. Synthesis of a trimannosylated-equipped archaeal diether lipid for the development of novel glycoliposomes. Carbohydrate Research, 2016, 435, pp.142--148. ⟨10.1016/j.carres.2016.10.003⟩. ⟨hal-01398046⟩
  • Cristine Gonçalves, Mathieu Berchel, Marie-Pierre Gosselin, Virginie Malard, Hervé Cheradame, et al.. Lipopolyplexes comprising imidazole/imidazolium lipophosphoramidate, histidinylated polyethyleneimine and siRNA as efficient formulation for siRNA transfection. International Journal of Pharmaceutics, 2014, 460 (1-2), pp.264-272. ⟨10.1016/j.ijpharm.2013.11.005⟩. ⟨hal-01179049⟩

Communication dans un congrès

  • C Delehedde, G Haifei, C Gonçalves, Virginie Malard, N Rameix, et al.. Influence of the charge of mRNA mannosylated lipopolyplexes on the binding and uptake by dendritic cells. 33e colloque Biotechnocentre, Oct 2021, Seillac, France. ⟨hal-03668427⟩

Poster

  • C Delehedde, G Haifei, Cristine Gonçalves, Virginie Malard, N Rameix, et al.. Influence of the charge of mRNA mannosylated lipopolyplexes on the binding and uptake by dendritic cells. 33e colloque Biotechnocentre, Oct 2021, Seillac, France. ⟨hal-03668442⟩

CHARPENTIER Stéphane

email : stephane.charpentier[remplacer_par_at]cnrs-orleans.fr

Téléphone : 02.38.25.55.96

Maître de conférence au sein du groupe thématique “Protéines de synthèse et chimie bioorthogonale”

 



23 documents

Article dans une revue

  • Saïd El Haddad, Amandine Serrano, Thierry Normand, Chloé Robin, Martine Dubois, et al.. Interaction of Alpha-synuclein with Cytogaligin, a protein encoded by the proapoptotic gene GALIG. Biochemical and Biophysical Research Communications, 2018, 495 (1), pp.787-792. ⟨10.1016/j.bbrc.2017.11.078⟩. ⟨hal-01966108⟩
  • Amandine Serrano, Saïd El Haddad, Fréderic Moal, Thierry Prazuck, Eric Legac, et al.. Dysregulation of apoptosis and autophagy gene expression in peripheral blood mononuclear cells of efficiently treated HIV-infected patients. AIDS. Official journal of the international AIDS Society, 2018, 32 (12), pp.1579 - 1587. ⟨10.1097/QAD.0000000000001851⟩. ⟨hal-01936094⟩
  • Lucile Mollet, Pauline Robinet, Martine Dubois, Axel Aurouet, Thierry Normand, et al.. Opposing Mcl-1, the GALIG proapoptotic gene is upregulated as neutrophils die and underexpressed in Acute Myeloid Leukemia cells.. Molecular Immunology, 2013, 56 (1-2), pp.123-8. ⟨10.1016/j.molimm.2013.04.012⟩. ⟨hal-00840170⟩
  • Pauline Robinet, Lucile Mollet, Patrick Gonzalez, Thierry Normand, Stephane Charpentier, et al.. The mitogaligin protein is addressed to the nucleus via a non-classical localization signal. Biochemical and Biophysical Research Communications, 2010, 392 (1), pp.53-57. ⟨10.1016/j.bbrc.2009.12.162⟩. ⟨hal-00529397⟩
  • Patrick Gonzalez, Pauline Robinet, Stéphane Charpentier, Lucile Mollet, Thierry Normand, et al.. Apoptotic activity of a nuclear form of mitogaligin, a cell death protein. Biochemical and Biophysical Research Communications, 2009, 378 (4), pp.816-820. ⟨10.1016/j.bbrc.2008.11.133⟩. ⟨hal-00522444⟩
  • Alexis D. Sennepin, Stéphane Charpentier, Thierry Normand, Cedric Sarre, Alain Legrand, et al.. Multiple reprobing of Western blots after inactivation of peroxidase activity by its substrate, hydrogen peroxide. Analytical Biochemistry, 2009, 393 (1), pp.129-131. ⟨10.1016/j.ab.2009.06.004⟩. ⟨hal-00525339⟩
  • Patrick Gonzalez, Mélanie Duneau, Stéphane Charpentier, Thierry Normand, Lucile Mollet, et al.. Destabilization of Membranes Containing Cardiolipin or Its Precursors by Peptides Derived from Mitogaligin, a Cell Death Protein. Biochemistry, 2007, 46 (25), pp.7374-7382. ⟨10.1021/bi700213p⟩. ⟨hal-00159568⟩
  • M. Duneau, M. Boyer Guittaut, P. Gonzalez, S. Charpentier, T. Normand, et al.. Galig, a novel cell death gene that encodes a mitochondrial protein promoting cytochrome c release. Experimental Cell Research, 2005, 302, pp.194-205. ⟨hal-00088588⟩
  • Michaël Guittaut, Stéphane Charpentier, Thierry Normand, Martine Dubois, Jacques Raimond, et al.. Identification of an Internal Gene to the Human Galectin-3 Gene with Two Different Overlapping Reading Frames That Do Not Encode Galectin-3. Journal of Biological Chemistry, 2001, 276 (4), pp.2652-2657. ⟨10.1074/jbc.m002523200⟩. ⟨hal-02137994⟩
  • Stéphane Charpentier, Mohamed Amiche, Jan Mester, Véronique Vouille, Jean-Pierre Le Caer, et al.. Structure, Synthesis, and Molecular Cloning of Dermaseptins B, a Family of Skin Peptide Antibiotics. Journal of Biological Chemistry, 1998, 273 (24), pp.14690-14697. ⟨10.1074/jbc.273.24.14690⟩. ⟨hal-02160836⟩
  • Stéphane Charpentier, Keith Jarvie, Diana Severynse, Marc G. Caron, Mario Tiberi. Silencing of the Constitutive Activity of the Dopamine D1B Receptor. Journal of Biological Chemistry, 1996, 271 (45), pp.28071-28076. ⟨10.1074/jbc.271.45.28071⟩. ⟨hal-02160838⟩
  • Stéphane Charpentier, S. Sagan, M Naim, A Delfour, P. Nicolas. Mechanism of delta-opioid receptor selection by the address domain of dermenkephalin.. European Journal of Pharmacology, 1994, 266 (2), pp.175-80. ⟨10.1016/0922-4106(94)90107-4⟩. ⟨hal-02160840⟩
  • Mohamed Naim, Stéphane Charpentier, Pierre Nicolas, Daniel Baron. Quantitative two-dimensional nmr study of dermenkephalin, a highly potent and selective ?-opioid peptide. Biopolymers, 1993, 33 (12), pp.1889-1900. ⟨10.1002/bip.360331214⟩. ⟨hal-02160842⟩
  • Sandrine Sagan, Stéphane Charpentier, Antoine Delfour, Mohamed Amiche, Pierre Nicolas. The aspartic acid in deltorphin I and dermenkephalin promotes targeting to δ-opioid receptor independently of receptor binding. Biochemical and Biophysical Research Communications, 1992, 187 (3), pp.1203-1210. ⟨10.1016/0006-291X(92)90431-J⟩. ⟨hal-02171853⟩
  • S Sagan, Stéphane Charpentier, M Naim, A Delfour, P Nicolas. Opioid peptides from amphibian skin: contribution of the amino acids of the "address" domain to the -selectivity of dermenkephalin. Peptides, 1992, pp.645-646. ⟨hal-02171902⟩
  • Stéphane Charpentier, Sandrine Sagan, Antoine Delfour, Pierre Nicolas. Dermenkephalin and deltorphin I reveal similarities within ligand-binding domains of μ- and δ-opioid receptors and an additional address subsite on the δ-receptor. Biochemical and Biophysical Research Communications, 1991, 179 (3), pp.1161-1168. ⟨10.1016/0006-291x(91)91693-7⟩. ⟨hal-02171883⟩
  • P Simon, Stéphane Charpentier, J. Costentin. An automated method for the assessment of spontaneous and stereotyped climbing behavior in mice. Effects of the selective D1- and D2-dopamine receptor agonists SKF-38393 and RU-24926 and their association.. Methods and findings in experimental and clinical pharmacology, 1991, 13 (2), pp.99-104. ⟨hal-02171886⟩
  • Jean Bralet, Claude Mossiat, Jeanne-Marie Lecomte, Stéphane Charpentier, Claude Gros, et al.. Diuretic and natriuretic responses in rats treated with enkephalinase inhibitors. European Journal of Pharmacology, 1990, 179 (1-2), pp.57-64. ⟨10.1016/0014-2999(90)90401-q⟩. ⟨hal-02171891⟩

Communication dans un congrès

  • S. El Haddad, A. Serrano, Thierry Normand, Fabienne Brulé-Morabito, L. Mollet, et al.. Cytogaligin, an additional link between Parkinson’s disease and autophagy pathways?. 7e Congrès du CFATG, Nov 2017, Paris, France. ⟨hal-02934905⟩
  • S El Haddad, A Serrano, C Ozsancak, P. Auzou, F Moal, et al.. Genes de l’autophagie : marqueurs sanguins potentiels de la maladie de Parkinson. Journées de Neurologie de Langue Française, Apr 2016, Nantes, France. ⟨hal-03661930⟩
  • A Serrano, T Guery, S El Haddad, M Dubois, M Schoenwald, et al.. GALIG, gène inducteur de la mort cellulaire, s’exprime au cours de la différenciation myéloïde. 10es Journées du Cancéropole Grand Ouest, Jun 2016, Les Sables d'Olonne, France. ⟨hal-03661932⟩
  • A Serrano, S El Haddad, T Normand, M Dubois, T Guery, et al.. Cytogaligin, one of the proteins produced by the proapoptotic GALIG gene, interacts with autophagy and proteasome molecules. 7th Proteasome Autophagy Workshop, Apr 2016, Clermont-Ferrand, France. ⟨hal-03661923⟩
  • A. Serrano, Thierry Normand, S. El Haddad, M. Dubois, Stéphane Charpentier, et al.. During efficient Anti-RetroViral (ARV) therapy, the expression of GALIG and its interacting partners involved in macroautophagy are deregulated. 6es Journées Scientifiques du CFATG, Oct 2016, Bordeaux, France. ⟨hal-02934903⟩