RAHMOUNI Rachid

email : rachid.rahmouni@cnrs-orleans.fr

Téléphone : 02.38.25.76.08

Bureau D205

Directeur de recherche au sein du Groupe thématique “Biologie de l’ARN et ARN thérapeutiques”

 



43 documents

Article dans une revue

  • Kévin Moreau, Aurélia Le Dantec, Christine Mosrin-Huaman, Yves Bigot, Benoit Piegu, et al.. Perturbation of mRNP biogenesis reveals a dynamic landscape of the Rrp6-dependent surveillance machinery trafficking along the yeast genome. RNA Biology, Taylor & Francis, 2019, pp.1-11. ⟨10.1080/15476286.2019.1593745⟩. ⟨hal-02117640⟩
  • Kévin Moreau, Justine Surand, Aurélia Le Dantec, Christine Mosrin-Huaman, Alain Legrand, et al.. Recombinant yeast and human cells as screening tools to search for antibacterial agents targeting the transcription termination factor Rho. Journal of Antibiotics, Nature Publishing Group: Open Access Hybrid Model Option B, 2018, 71 (4), pp.447-455. ⟨hal-01966171⟩
  • Christine Mosrin-Huaman, Nadège Hervouet-Coste, A. Rachid Rahmouni. Co-transcriptional degradation by the 5′-3′ exonuclease Rat1p mediates quality control of HXK1 mRNP biogenesis in S. cerevisiae. RNA Biology, Taylor & Francis, 2016, 13 (6), pp.582 - 592. ⟨10.1080/15476286.2016.1181255⟩. ⟨hal-01407513⟩
  • Rachid A. Rahmouni, Christine Mosrin-Huaman. In Situ Footprinting of E. coli Transcription Elongation Complex with Chloroacetaldehyde. Methods in Molecular Biology, Humana Press/Springer Imprint, 2015, Methods in Molecular Biology, 1276, pp.229-240. ⟨10.1007/978-1-4939-2392-2_13⟩. ⟨hal-01171857⟩
  • Christine Mosrin-Huaman, Nadege Hervouet-Coste, Aurélia Le Dantec, Igor Stuparevic, A. Rachid Rahmouni. Bacterial Rho helicase: a new tool to dissect mRNP biogenesis and quality control in yeast. Trends in cell and molecular biology, Research Trends, 2014, 9, pp.79 - 93. ⟨hal-01179495⟩
  • Igor Stuparevic, Christine Mosrin-Huaman, Nadège Hervouet-Coste, Mateja Remenaric, A. Rachid Rahmouni. Co-transcriptional recruitment of the RNA exosome cofactors Rrp47p, Mpp6p and two distinct TRAMP complexes assists the exonuclease Rrp6p in the targeting and degradation of an aberrant mRNP in yeast. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2013, ⟨10.1074/jbc.M113.491290⟩. ⟨hal-00874892⟩
  • Romy Honorine, Christine Mosrin-Huaman, Nadege Hervouet-Coste, Domenico Libri, Rachid A. Rahmouni. Nuclear mRNA quality control in yeast is mediated by Nrd1 co-transcriptional recruitment, as revealed by the targeting of Rho-induced aberrant transcripts. Nucleic Acids Research, Oxford University Press, 2011, 39 (7), pp.2809-2820. ⟨10.1093/nar/gkq1192⟩. ⟨hal-00602376⟩
  • Makhlouf Rabhi, Olivier Espéli, Annie Schwartz, Bastien Cayrol, a Rachid Rahmouni, et al.. The Sm-like RNA chaperone Hfq mediates transcription antitermination at Rho-dependent terminators.. EMBO Journal, EMBO Press, 2011, 30 (14), pp.2805-16. ⟨10.1038/emboj.2011.192⟩. ⟨hal-00720713⟩
  • Sergey Proshkin, A. Rachid Rahmouni, Alexander Mironov, Evgeny Nudler. Cooperation between Translating Ribosomes and RNA Polymerase in Transcription. Science, American Association for the Advancement of Science, 2010, 328 (5977), pp.504-508. ⟨10.1126/science.1184939⟩. ⟨hal-00529391⟩
  • Christine Mosrin-Huaman, Romy Honorine, A. Rachid Rahmouni. Expression of Bacterial Rho Factor in Yeast Identifies New Factors Involved in the Functional Interplay between Transcription and mRNP Biogenesis. Molecular and Cellular Biology, American Society for Microbiology, 2009, 29 (15), pp.4033-4044. ⟨10.1128/MCB.00272-09⟩. ⟨hal-00525149⟩
  • Annie Schwartz, Makhlouf Rabhi, Frederique Jacquinot, Emmanuel Margeat, A. Rachid Rahmouni, et al.. A stepwise 2 '-hydroxyl activation mechanism for the bacterial transcription termination factor Rho helicase. Nature Structural and Molecular Biology, Nature Publishing Group, 2009, 16 (12), pp.1309-1316. ⟨10.1038/nsmb.1711⟩. ⟨hal-00525325⟩
  • Annie Schwartz, Céline Walmacq, A. Rachid Rahmouni, Marc Boudvillain. Noncanonical Interactions in the Management of RNA Structural Blocks by the Transcription Termination Rho Helicase. Biochemistry, American Chemical Society, 2007, 46 (33), pp.9366 - 9379. ⟨10.1021/bi700493m⟩. ⟨hal-00166551⟩
  • Annie Schwartz, Emmanuel Margeat, A. Rachid Rahmouni, Marc Boudvillain. Transcription termination factor Rho can displace streptavidin from biotinylated RNA. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2007, 282 (43), pp.31469-31476. ⟨10.1074/jbc.M706935200⟩. ⟨hal-00176284⟩
  • V. Nagarajavel, S. Madhusudan, S. Dole, Ar. Rahmouni, K. Schnetz. Repression by binding of H-NS within the transcription unit. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2007, 282, pp.23622-23630. ⟨hal-00282443⟩
  • C. Walmacq, A.R. Rahmouni, M. Boudvillain. Testing the steric exclusion model for hexameric helicases: substrate features that alter RNA-DNA unwinding by the transcription termination factor Rho. Biochemistry, American Chemical Society, 2006, 45, pp.5885-5895. ⟨10.1021/bi0600648⟩. ⟨hal-00088941⟩
  • L. Moulin, A.R. Rahmouni, F. Boccard. Topological insulators inhibit diffusion of transcription-induced positive supercoils in the chromosome of Escherichia coli. Molecular Microbiology, Wiley, 2005, 55, pp.601-610. ⟨hal-00088662⟩
  • F. ToulmÉ, C. Mosrin-Huaman, I. Artsimovitch, A.R. Rahmouni. Transcriptional pausing in vivo: a nascent RNA hairpin restricts lateral movements of RNA polymerase in both forward and reverse directions. Journal of Molecular Biology, Elsevier, 2005, 351, pp.39-51. ⟨hal-00088714⟩
  • C. Mosrin-Huaman, C.L. Turnbough, A.R. Rahmouni. Translocation of Escherichia coli RNA polymerase against a protein roadblock in vivo highlights a passive sliding mechanism for transcript elongation. Molecular Microbiology, Wiley, 2004, 51, pp.1471-1481. ⟨hal-00113075⟩
  • E. Vieu, Rahmouni A.R.. Dual role of boxB RNA motif in the mechanisms of termination/antitermination at the lambda tR1 terminator revealed in vivo. Journal of Molecular Biology, Elsevier, 2004, 339, pp.1077-1087. ⟨hal-00113087⟩
  • C. Walmacq, A.R. Rahmouni, M. Boudvillain. Influence of substrate composition on the helicase activity of transcription termination factor Rho: reduced processivity of Rho hexamers during unwinding of RNA-DNA hybrid regions. Journal of Molecular Biology, Elsevier, 2004, 342 (2), pp.403-420. ⟨10.1016/j.jmb.2004.07.026⟩. ⟨hal-00113090⟩
  • V. Epshtein, F. ToulmÉ, A.R. Rahmouni, S. Borukhov, E. Nudler. Transcription through the roadblocks: the role of RNA polymerase cooperation. EMBO Journal, EMBO Press, 2003, 22, pp.4719-4727. ⟨hal-00088176⟩
  • A. Schwartz, A. Rachid Rahmouni, Marc Boudvillain. The functional anatomy of an intrinsic transcription terminator. EMBO Journal, EMBO Press, 2003, 22 (13), pp.3385 - 3394. ⟨10.1093/emboj/cdg310⟩. ⟨hal-01880611⟩
  • Marc Boudvillain, Annie Schwartz, A. Rachid Rahmouni. Limited Topological Alteration of the T7 RNA Polymerase Active Center at Intrinsic Termination Sites †. Biochemistry, American Chemical Society, 2002, 41 (9), pp.3137-3146. ⟨10.1021/bi011358q⟩. ⟨hal-02075291⟩
  • F Toulmé, M Mosrin-Huaman, J Sparkowski, A. Das, M. Leng, et al.. GreA and GreB proteins revive backtracked RNA polymerase in vivo by promoting transcript trimming. EMBO Journal, EMBO Press, 2000, 19 (24), pp.6853-6859. ⟨10.1093/emboj/19.24.6853⟩. ⟨hal-02127250⟩
  • F. ToulmÉ, M Guérin, N. Robichon, M. Leng, A. Rachid Rahmouni. In vivo evidence for back and forth oscillations of the transcription elongation complex. EMBO Journal, EMBO Press, 1999, 18 (18), pp.5052-5060. ⟨10.1093/emboj/18.18.5052⟩. ⟨hal-02127238⟩
  • M Guerin, N. Robichon, J. Geiselmann, A. Rachid Rahmouni. A simple polypyrimidine repeat acts as an artificial Rho-dependent terminator in vivo and in vitro. Nucleic Acids Research, Oxford University Press, 1998, 26 (21), pp.4895-4900. ⟨10.1093/nar/26.21.4895⟩. ⟨hal-02127232⟩
  • N. Figueroa-Bossi, M Guérin, A. Rachid Rahmouni, M Leng, L Bossi. The supercoiling sensitivity of a bacterial tRNA promoter parallels its responsiveness to stringent control. EMBO Journal, EMBO Press, 1998, 17 (8), pp.2359-2367. ⟨10.1093/emboj/17.8.2359⟩. ⟨hal-02127234⟩
  • A. Albert, F Spirito, N Bossi, L Bossi, A. Rachid Rahmouni. Hyper-negative template DNA supercoiling during transcription of the tetracycline-resistance gene in topA mutants is largely constrained in vivo. Nucleic Acids Research, Oxford University Press, 1996, 24 (15), pp.3093-3099. ⟨10.1093/nar/24.15.3093⟩. ⟨hal-02127221⟩
  • M Guérin, M. Leng, A. Rachid Rahmouni. High resolution mapping of E.coli transcription elongation complex in situ reveals protein interactions with the non-transcribed strand.. EMBO Journal, EMBO Press, 1996, 15 (19), pp.5397-5407. ⟨hal-02127225⟩
  • Annie-Claude Albert, Marc Leng, A. Rachid Rahmouni. The Size of the Topological Domain Modulates the B-Z Transition of a (TG) n Containing Repeat. Journal of Biomolecular Structure and Dynamics, Taylor & Francis: STM, Behavioural Science and Public Health Titles, 1995, 13 (1), pp.47-56. ⟨10.1080/07391102.1995.10508820⟩. ⟨hal-02127217⟩
  • A.C Albert, A. Roman, G. Bouche, M. Leng, A. Rachid Rahmouni. Gradual and oriented B-Z transition in 5'-untranscribed region of mouse ribosomal DNA.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1994, 269 (30), pp.19238-44. ⟨hal-02127210⟩
  • Laurence Tartier, Veslav Michalik, Melanie Spotheim-Maurizot, A. Rachid Rahmouni, Roland Sabattier, et al.. Radiolytic signature of Z-DNA. Nucleic Acids Research, Oxford University Press, 1994, 22 (25), pp.5565-5570. ⟨10.1093/nar/22.25.5565⟩. ⟨hal-02127214⟩
  • A. Rachid Rahmouni. Z-DNA as a probe for localized supercoiling in vivo. Molecular Microbiology, Wiley, 1992, 6 (5), pp.569-572. ⟨10.1111/j.1365-2958.1992.tb01502.x⟩. ⟨hal-02127207⟩
  • A. Rachid Rahmouni, R Wells. Direct evidence for the effect of transcription on local DNA supercoiling in vivo.. Journal of Molecular Biology, Elsevier, 1992, 223 (1), pp.131-44. ⟨hal-02127204⟩
  • M. Lemaire, A. Rachid Rahmouni, A. Schwartz, M. Leng. Interstrand cross-links are preferentially formed at the d(GC) sites in the reaction between cis-diamminedichloroplatinum (II) and DNA.. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 1991, 88 (5), pp.1982-1985. ⟨10.1073/pnas.88.5.1982⟩. ⟨hal-02127202⟩
  • R Rajagopalan, A. Rachid Rahmouni, R Wells. Flanking AT-rich tracts cause a structural distortion in Z-DNA in plasmids.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1990, 265 (28), pp.17294-9. ⟨hal-02127194⟩
  • K Mazeau, F. Vovelle, A. Rachid Rahmouni, M. Leng, M. Ptak. Structure of the intrastrand cis-[Pt(NH3)2(d(GpCpG))] adduct in a dodecanucleotide duplex: II. A molecular mechanics modeling study.. Anti-Cancer Drug Design, 1989, 4 (1), pp.63-78. ⟨hal-02127180⟩
  • M. Ptak, A. Rachid Rahmouni, K Mazeau, N Thuong, M. Leng. Structure of the intrastrand cis-[Pt(NH3)2(d(GpCpG))] adduct in a dodecanucleotide duplex: I. A 1H and 31P n.m.r. study.. Anti-Cancer Drug Design, 1989, 4 (1), pp.53-61. ⟨hal-02127173⟩
  • A. Rachid Rahmouni, R Wells. Stabilization of Z DNA in vivo by localized supercoiling.. Science, American Association for the Advancement of Science, 1989, 246 (4928), pp.358-63. ⟨hal-02127190⟩
  • A. Rachid Rahmouni, M. Leng. Reaction of nucleic acids with cis-diamminedichloroplatinum(II): interstrand cross-links.. Biochemistry, American Chemical Society, 1987, 26 (23), pp.7229-34. ⟨hal-02127140⟩
  • A. Rachid Rahmouni, Jean-Marc Malinge, Annie Schwartz, Marc Leng. Comparison Between poly(dG-dC)·poly(dG-dC) and DNA Modified by cis-diamminedichloroplatinum (II): Immunological and Spectroscopic Studies. Journal of Biomolecular Structure and Dynamics, Taylor & Francis: STM, Behavioural Science and Public Health Titles, 1985, 3 (2), pp.363-375. ⟨10.1080/07391102.1985.10508423⟩. ⟨hal-02127084⟩

Chapitre d'ouvrage

  • Makhlouf Rabhi, Rahmouni Rachid A., Marc Boudvillain. Transcription termination factor Rho: a ring-shaped RNA helicase from bacteria. Eckhard Jankowsky. RNA helicases, Royal Society of Chemistry Publishing, pp.243-271, 2010, ⟨10.1039/9781849732215-00243⟩. ⟨hal-00610004⟩
  • A. Rachid Rahmouni, A. Schwartz, M. Leng. Importance of DNA Sequence in the Reaction of d(ApG) and d(GpA) with Cis-Diamminedichloroplatinum (II). Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy: Proceedings of the Fifth International Symposium on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy Abano, Padua, ITALY - June 29–July 2, 1987, Springer US, pp.127-131, 1988. ⟨hal-02127164⟩

SUET Amandine

email : amandine.suet@cnrs-orleans.fr

Téléphone : 02.38.25.78.18

Bureau A215

Assistante ingénieure en biologie, sciences de la vie et de la terre au sein des groupes thématiques “Biologie de l’ARN et ARN thérapeutiques” et “Biologie de la peau”

 



0 documents

PERCHE Federico

email : federico.perche@cnrs-orleans.fr

Téléphone : 02.38.25.55.65

Bureau A212

Chargé de recherche au sein des Groupes thématiques “Biologie de l’ARN et ARN thérapeutiques” et “Thérapies innovantes et nanomédecine”



documents

PICHON Chantal

email : chantal.pichon@cnrs-orleans.fr

Téléphone : 02.38.25.55.95

Bureau A216

Professeur, coordinatrice de l’équipe “Biologie cellulaire, cibles moléculaires et thérapies innovantes”, co-responsable du groupe thématique “Biologie de l’ARN et ARN thérapeutiques” et co-responsable du groupe thématique “Biologie de la peau”



documents

MALARD Virginie

email : virginie.malard@cnrs-orleans.fr

Téléphone : 02.38.25.56.23

Bureau A213

Assistante ingénieure en analyse chimique au sein des groupes thématiques “Thérapies innovantes et nanomédecine” et “Biologie de l’ARN et ARN thérapeutiques”

 



5 documents

Article dans une revue