MOSRIN-HUAMAN Christine

email : christine.mosrin@cnrs-orleans.fr

Téléphone : 02.38.25.78.08

Bureau D204

Chargée de recherche au sein du Groupe thématique “Biologie de l’ARN et ARN thérapeutiques”

 



10 documents

Article dans une revue

  • Kévin Moreau, Aurélia Le Dantec, Christine Mosrin-Huaman, Yves Bigot, Benoit Piegu, et al.. Perturbation of mRNP biogenesis reveals a dynamic landscape of the Rrp6-dependent surveillance machinery trafficking along the yeast genome. RNA Biology, Taylor & Francis, 2019, pp.1-11. ⟨10.1080/15476286.2019.1593745⟩. ⟨hal-02117640⟩
  • Kévin Moreau, Justine Surand, Aurélia Le Dantec, Christine Mosrin-Huaman, Alain Legrand, et al.. Recombinant yeast and human cells as screening tools to search for antibacterial agents targeting the transcription termination factor Rho. Journal of Antibiotics, Nature Publishing Group: Open Access Hybrid Model Option B, 2018, 71 (4), pp.447-455. ⟨hal-01966171⟩
  • Christine Mosrin-Huaman, Nadège Hervouet-Coste, A. Rachid Rahmouni. Co-transcriptional degradation by the 5′-3′ exonuclease Rat1p mediates quality control of HXK1 mRNP biogenesis in S. cerevisiae. RNA Biology, Taylor & Francis, 2016, 13 (6), pp.582 - 592. ⟨10.1080/15476286.2016.1181255⟩. ⟨hal-01407513⟩
  • Rachid A. Rahmouni, Christine Mosrin-Huaman. In Situ Footprinting of E. coli Transcription Elongation Complex with Chloroacetaldehyde. Methods in Molecular Biology, Humana Press/Springer Imprint, 2015, Methods in Molecular Biology, 1276, pp.229-240. ⟨10.1007/978-1-4939-2392-2_13⟩. ⟨hal-01171857⟩
  • Christine Mosrin-Huaman, Nadege Hervouet-Coste, Aurélia Le Dantec, Igor Stuparevic, A. Rachid Rahmouni. Bacterial Rho helicase: a new tool to dissect mRNP biogenesis and quality control in yeast. Trends in cell and molecular biology, Research Trends, 2014, 9, pp.79 - 93. ⟨hal-01179495⟩
  • Igor Stuparevic, Christine Mosrin-Huaman, Nadège Hervouet-Coste, Mateja Remenaric, A. Rachid Rahmouni. Co-transcriptional recruitment of the RNA exosome cofactors Rrp47p, Mpp6p and two distinct TRAMP complexes assists the exonuclease Rrp6p in the targeting and degradation of an aberrant mRNP in yeast. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2013, ⟨10.1074/jbc.M113.491290⟩. ⟨hal-00874892⟩
  • Romy Honorine, Christine Mosrin-Huaman, Nadege Hervouet-Coste, Domenico Libri, Rachid A. Rahmouni. Nuclear mRNA quality control in yeast is mediated by Nrd1 co-transcriptional recruitment, as revealed by the targeting of Rho-induced aberrant transcripts. Nucleic Acids Research, Oxford University Press, 2011, 39 (7), pp.2809-2820. ⟨10.1093/nar/gkq1192⟩. ⟨hal-00602376⟩
  • Christine Mosrin-Huaman, Romy Honorine, A. Rachid Rahmouni. Expression of Bacterial Rho Factor in Yeast Identifies New Factors Involved in the Functional Interplay between Transcription and mRNP Biogenesis. Molecular and Cellular Biology, American Society for Microbiology, 2009, 29 (15), pp.4033-4044. ⟨10.1128/MCB.00272-09⟩. ⟨hal-00525149⟩
  • F. ToulmÉ, C. Mosrin-Huaman, I. Artsimovitch, A.R. Rahmouni. Transcriptional pausing in vivo: a nascent RNA hairpin restricts lateral movements of RNA polymerase in both forward and reverse directions. Journal of Molecular Biology, Elsevier, 2005, 351, pp.39-51. ⟨hal-00088714⟩
  • C. Mosrin-Huaman, C.L. Turnbough, A.R. Rahmouni. Translocation of Escherichia coli RNA polymerase against a protein roadblock in vivo highlights a passive sliding mechanism for transcript elongation. Molecular Microbiology, Wiley, 2004, 51, pp.1471-1481. ⟨hal-00113075⟩

 

RAHMOUNI Rachid

email : rachid.rahmouni@cnrs-orleans.fr

Téléphone : 02.38.25.76.08

Bureau D205

Directeur de recherche au sein du Groupe thématique “Biologie de l’ARN et ARN thérapeutiques”

 



43 documents

Article dans une revue

  • Kévin Moreau, Aurélia Le Dantec, Christine Mosrin-Huaman, Yves Bigot, Benoit Piegu, et al.. Perturbation of mRNP biogenesis reveals a dynamic landscape of the Rrp6-dependent surveillance machinery trafficking along the yeast genome. RNA Biology, Taylor & Francis, 2019, pp.1-11. ⟨10.1080/15476286.2019.1593745⟩. ⟨hal-02117640⟩
  • Kévin Moreau, Justine Surand, Aurélia Le Dantec, Christine Mosrin-Huaman, Alain Legrand, et al.. Recombinant yeast and human cells as screening tools to search for antibacterial agents targeting the transcription termination factor Rho. Journal of Antibiotics, Nature Publishing Group: Open Access Hybrid Model Option B, 2018, 71 (4), pp.447-455. ⟨hal-01966171⟩
  • Christine Mosrin-Huaman, Nadège Hervouet-Coste, A. Rachid Rahmouni. Co-transcriptional degradation by the 5′-3′ exonuclease Rat1p mediates quality control of HXK1 mRNP biogenesis in S. cerevisiae. RNA Biology, Taylor & Francis, 2016, 13 (6), pp.582 - 592. ⟨10.1080/15476286.2016.1181255⟩. ⟨hal-01407513⟩
  • Rachid A. Rahmouni, Christine Mosrin-Huaman. In Situ Footprinting of E. coli Transcription Elongation Complex with Chloroacetaldehyde. Methods in Molecular Biology, Humana Press/Springer Imprint, 2015, Methods in Molecular Biology, 1276, pp.229-240. ⟨10.1007/978-1-4939-2392-2_13⟩. ⟨hal-01171857⟩
  • Christine Mosrin-Huaman, Nadege Hervouet-Coste, Aurélia Le Dantec, Igor Stuparevic, A. Rachid Rahmouni. Bacterial Rho helicase: a new tool to dissect mRNP biogenesis and quality control in yeast. Trends in cell and molecular biology, Research Trends, 2014, 9, pp.79 - 93. ⟨hal-01179495⟩
  • Igor Stuparevic, Christine Mosrin-Huaman, Nadège Hervouet-Coste, Mateja Remenaric, A. Rachid Rahmouni. Co-transcriptional recruitment of the RNA exosome cofactors Rrp47p, Mpp6p and two distinct TRAMP complexes assists the exonuclease Rrp6p in the targeting and degradation of an aberrant mRNP in yeast. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2013, ⟨10.1074/jbc.M113.491290⟩. ⟨hal-00874892⟩
  • Makhlouf Rabhi, Olivier Espéli, Annie Schwartz, Bastien Cayrol, A Rachid Rahmouni, et al.. The Sm-like RNA chaperone Hfq mediates transcription antitermination at Rho-dependent terminators.. EMBO Journal, EMBO Press, 2011, 30 (14), pp.2805-16. ⟨10.1038/emboj.2011.192⟩. ⟨hal-00720713⟩
  • Romy Honorine, Christine Mosrin-Huaman, Nadege Hervouet-Coste, Domenico Libri, Rachid A. Rahmouni. Nuclear mRNA quality control in yeast is mediated by Nrd1 co-transcriptional recruitment, as revealed by the targeting of Rho-induced aberrant transcripts. Nucleic Acids Research, Oxford University Press, 2011, 39 (7), pp.2809-2820. ⟨10.1093/nar/gkq1192⟩. ⟨hal-00602376⟩
  • Sergey Proshkin, A. Rachid Rahmouni, Alexander Mironov, Evgeny Nudler. Cooperation between Translating Ribosomes and RNA Polymerase in Transcription. Science, American Association for the Advancement of Science, 2010, 328 (5977), pp.504-508. ⟨10.1126/science.1184939⟩. ⟨hal-00529391⟩
  • Annie Schwartz, Makhlouf Rabhi, Frederique Jacquinot, Emmanuel Margeat, A. Rachid Rahmouni, et al.. A stepwise 2 '-hydroxyl activation mechanism for the bacterial transcription termination factor Rho helicase. Nature Structural and Molecular Biology, Nature Publishing Group, 2009, 16 (12), pp.1309-1316. ⟨10.1038/nsmb.1711⟩. ⟨hal-00525325⟩
  • Christine Mosrin-Huaman, Romy Honorine, A. Rachid Rahmouni. Expression of Bacterial Rho Factor in Yeast Identifies New Factors Involved in the Functional Interplay between Transcription and mRNP Biogenesis. Molecular and Cellular Biology, American Society for Microbiology, 2009, 29 (15), pp.4033-4044. ⟨10.1128/MCB.00272-09⟩. ⟨hal-00525149⟩
  • Annie Schwartz, Emmanuel Margeat, A. Rachid Rahmouni, Marc Boudvillain. Transcription termination factor Rho can displace streptavidin from biotinylated RNA. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2007, 282 (43), pp.31469-31476. ⟨10.1074/jbc.M706935200⟩. ⟨hal-00176284⟩
  • V. Nagarajavel, S. Madhusudan, S. Dole, Ar. Rahmouni, K. Schnetz. Repression by binding of H-NS within the transcription unit. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2007, 282, pp.23622-23630. ⟨hal-00282443⟩
  • Annie Schwartz, Céline Walmacq, A. Rachid Rahmouni, Marc Boudvillain. Noncanonical Interactions in the Management of RNA Structural Blocks by the Transcription Termination Rho Helicase. Biochemistry, American Chemical Society, 2007, 46 (33), pp.9366 - 9379. ⟨10.1021/bi700493m⟩. ⟨hal-00166551⟩
  • C. Walmacq, A.R. Rahmouni, M. Boudvillain. Testing the steric exclusion model for hexameric helicases: substrate features that alter RNA-DNA unwinding by the transcription termination factor Rho. Biochemistry, American Chemical Society, 2006, 45, pp.5885-5895. ⟨10.1021/bi0600648⟩. ⟨hal-00088941⟩
  • F. ToulmÉ, C. Mosrin-Huaman, I. Artsimovitch, A.R. Rahmouni. Transcriptional pausing in vivo: a nascent RNA hairpin restricts lateral movements of RNA polymerase in both forward and reverse directions. Journal of Molecular Biology, Elsevier, 2005, 351, pp.39-51. ⟨hal-00088714⟩
  • L. Moulin, A.R. Rahmouni, F. Boccard. Topological insulators inhibit diffusion of transcription-induced positive supercoils in the chromosome of Escherichia coli. Molecular Microbiology, Wiley, 2005, 55, pp.601-610. ⟨hal-00088662⟩
  • E. Vieu, Rahmouni A.R.. Dual role of boxB RNA motif in the mechanisms of termination/antitermination at the lambda tR1 terminator revealed in vivo. Journal of Molecular Biology, Elsevier, 2004, 339, pp.1077-1087. ⟨hal-00113087⟩
  • C. Walmacq, A.R. Rahmouni, M. Boudvillain. Influence of substrate composition on the helicase activity of transcription termination factor Rho: reduced processivity of Rho hexamers during unwinding of RNA-DNA hybrid regions. Journal of Molecular Biology, Elsevier, 2004, 342 (2), pp.403-420. ⟨10.1016/j.jmb.2004.07.026⟩. ⟨hal-00113090⟩
  • C. Mosrin-Huaman, C.L. Turnbough, A.R. Rahmouni. Translocation of Escherichia coli RNA polymerase against a protein roadblock in vivo highlights a passive sliding mechanism for transcript elongation. Molecular Microbiology, Wiley, 2004, 51, pp.1471-1481. ⟨hal-00113075⟩
  • A. Schwartz, A. Rachid Rahmouni, Marc Boudvillain. The functional anatomy of an intrinsic transcription terminator. EMBO Journal, EMBO Press, 2003, 22 (13), pp.3385 - 3394. ⟨10.1093/emboj/cdg310⟩. ⟨hal-01880611⟩
  • V. Epshtein, F. ToulmÉ, A.R. Rahmouni, S. Borukhov, E. Nudler. Transcription through the roadblocks: the role of RNA polymerase cooperation. EMBO Journal, EMBO Press, 2003, 22, pp.4719-4727. ⟨hal-00088176⟩
  • Marc Boudvillain, Annie Schwartz, A. Rachid Rahmouni. Limited Topological Alteration of the T7 RNA Polymerase Active Center at Intrinsic Termination Sites †. Biochemistry, American Chemical Society, 2002, 41 (9), pp.3137-3146. ⟨10.1021/bi011358q⟩. ⟨hal-02075291⟩
  • F Toulmé, M Mosrin-Huaman, J Sparkowski, A. Das, M. Leng, et al.. GreA and GreB proteins revive backtracked RNA polymerase in vivo by promoting transcript trimming. The EMBO Journal, 2000, 19 (24), pp.6853-6859. ⟨10.1093/emboj/19.24.6853⟩. ⟨hal-02127250⟩
  • F. ToulmÉ, M Guérin, N. Robichon, M. Leng, A. Rachid Rahmouni. In vivo evidence for back and forth oscillations of the transcription elongation complex. The EMBO Journal, 1999, 18 (18), pp.5052-5060. ⟨10.1093/emboj/18.18.5052⟩. ⟨hal-02127238⟩
  • N. Figueroa-Bossi, M Guérin, A. Rachid Rahmouni, M Leng, L Bossi. The supercoiling sensitivity of a bacterial tRNA promoter parallels its responsiveness to stringent control. The EMBO Journal, 1998, 17 (8), pp.2359-2367. ⟨10.1093/emboj/17.8.2359⟩. ⟨hal-02127234⟩
  • M Guerin, N. Robichon, J. Geiselmann, A. Rachid Rahmouni. A simple polypyrimidine repeat acts as an artificial Rho-dependent terminator in vivo and in vitro. Nucleic Acids Research, Oxford University Press, 1998, 26 (21), pp.4895-4900. ⟨10.1093/nar/26.21.4895⟩. ⟨hal-02127232⟩
  • M Guérin, M. Leng, A. Rachid Rahmouni. High resolution mapping of E.coli transcription elongation complex in situ reveals protein interactions with the non-transcribed strand.. EMBO Journal, EMBO Press, 1996, 15 (19), pp.5397-5407. ⟨hal-02127225⟩
  • A. Albert, F Spirito, N Bossi, L Bossi, A. Rachid Rahmouni. Hyper-negative template DNA supercoiling during transcription of the tetracycline-resistance gene in topA mutants is largely constrained in vivo. Nucleic Acids Research, Oxford University Press, 1996, 24 (15), pp.3093-3099. ⟨10.1093/nar/24.15.3093⟩. ⟨hal-02127221⟩
  • Annie-Claude Albert, Marc Leng, A. Rachid Rahmouni. The Size of the Topological Domain Modulates the B-Z Transition of a (TG) n Containing Repeat. Journal of Biomolecular Structure and Dynamics, Taylor & Francis: STM, Behavioural Science and Public Health Titles, 1995, 13 (1), pp.47-56. ⟨10.1080/07391102.1995.10508820⟩. ⟨hal-02127217⟩
  • Laurence Tartier, Veslav Michalik, Melanie Spotheim-Maurizot, A. Rachid Rahmouni, Roland Sabattier, et al.. Radiolytic signature of Z-DNA. Nucleic Acids Research, Oxford University Press, 1994, 22 (25), pp.5565-5570. ⟨10.1093/nar/22.25.5565⟩. ⟨hal-02127214⟩
  • A.C Albert, A. Roman, G. Bouche, M. Leng, A. Rachid Rahmouni. Gradual and oriented B-Z transition in 5'-untranscribed region of mouse ribosomal DNA.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1994, 269 (30), pp.19238-44. ⟨hal-02127210⟩
  • A. Rachid Rahmouni, R Wells. Direct evidence for the effect of transcription on local DNA supercoiling in vivo.. Journal of Molecular Biology, Elsevier, 1992, 223 (1), pp.131-44. ⟨hal-02127204⟩
  • A. Rachid Rahmouni. Z-DNA as a probe for localized supercoiling in vivo. Molecular Microbiology, Wiley, 1992, 6 (5), pp.569-572. ⟨10.1111/j.1365-2958.1992.tb01502.x⟩. ⟨hal-02127207⟩
  • M. Lemaire, A. Rachid Rahmouni, A. Schwartz, M. Leng. Interstrand cross-links are preferentially formed at the d(GC) sites in the reaction between cis-diamminedichloroplatinum (II) and DNA.. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 1991, 88 (5), pp.1982-1985. ⟨10.1073/pnas.88.5.1982⟩. ⟨hal-02127202⟩
  • R Rajagopalan, A. Rachid Rahmouni, R Wells. Flanking AT-rich tracts cause a structural distortion in Z-DNA in plasmids.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1990, 265 (28), pp.17294-9. ⟨hal-02127194⟩
  • K Mazeau, F. Vovelle, A. Rachid Rahmouni, M. Leng, M. Ptak. Structure of the intrastrand cis-[Pt(NH3)2(d(GpCpG))] adduct in a dodecanucleotide duplex: II. A molecular mechanics modeling study.. Anti-Cancer Drug Design, 1989, 4 (1), pp.63-78. ⟨hal-02127180⟩
  • M. Ptak, A. Rachid Rahmouni, K Mazeau, N Thuong, M. Leng. Structure of the intrastrand cis-[Pt(NH3)2(d(GpCpG))] adduct in a dodecanucleotide duplex: I. A 1H and 31P n.m.r. study.. Anti-Cancer Drug Design, 1989, 4 (1), pp.53-61. ⟨hal-02127173⟩
  • A. Rachid Rahmouni, R Wells. Stabilization of Z DNA in vivo by localized supercoiling.. Science, American Association for the Advancement of Science, 1989, 246 (4928), pp.358-63. ⟨hal-02127190⟩
  • A. Rachid Rahmouni, M. Leng. Reaction of nucleic acids with cis-diamminedichloroplatinum(II): interstrand cross-links.. Biochemistry, American Chemical Society, 1987, 26 (23), pp.7229-34. ⟨hal-02127140⟩
  • A. Rachid Rahmouni, Jean-Marc Malinge, Annie Schwartz, Marc Leng. Comparison Between poly(dG-dC)·poly(dG-dC) and DNA Modified by cis-diamminedichloroplatinum (II): Immunological and Spectroscopic Studies. Journal of Biomolecular Structure and Dynamics, Taylor & Francis: STM, Behavioural Science and Public Health Titles, 1985, 3 (2), pp.363-375. ⟨10.1080/07391102.1985.10508423⟩. ⟨hal-02127084⟩

Chapitre d'ouvrage

  • Makhlouf Rabhi, Rahmouni Rachid A., Marc Boudvillain. Transcription termination factor Rho: a ring-shaped RNA helicase from bacteria. Eckhard Jankowsky. RNA helicases, Royal Society of Chemistry Publishing, pp.243-271, 2010, ⟨10.1039/9781849732215-00243⟩. ⟨hal-00610004⟩
  • A. Rachid Rahmouni, A. Schwartz, M. Leng. Importance of DNA Sequence in the Reaction of d(ApG) and d(GpA) with Cis-Diamminedichloroplatinum (II). Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy: Proceedings of the Fifth International Symposium on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy Abano, Padua, ITALY - June 29–July 2, 1987, Springer US, pp.127-131, 1988. ⟨hal-02127164⟩

SUET Amandine

email : amandine.suet@cnrs-orleans.fr

Téléphone : 02.38.25.78.18

Bureau A215

Assistante ingénieure en biologie, sciences de la vie et de la terre au sein des groupes thématiques “Biologie de l’ARN et ARN thérapeutiques” et “Biologie de la peau”

 



0 documents

PERCHE Federico

email : federico.perche@cnrs-orleans.fr

Téléphone : 02.38.25.55.65

Bureau A212

Chargé de recherche au sein des Groupes thématiques “Biologie de l’ARN et ARN thérapeutiques” et “Thérapies innovantes et nanomédecine”



22 documents

Article dans une revue

  • Yu Yi, Hyun Jin Kim, Meng Zheng, Peng Mi, Mitsuru Mi, et al.. Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells. Journal of Controlled Release, Elsevier, 2019, 295, pp.268-277. ⟨10.1016/j.jconrel.2019.01.006⟩. ⟨hal-02067488⟩
  • Kevin Van Der Jeught, Stefaan de Koker, Lukasz Bialkowski, Carlo Heirman, Patrick Tjok Joe, et al.. Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety. ACS Nano, American Chemical Society, 2018, 12 (10), pp.9815-9829. ⟨https://pubs.acs.org/doi/10.1021/acsnano.8b00966⟩. ⟨10.1021/acsnano.8b00966⟩. ⟨hal-01889829⟩
  • Federico Perche, Satoshi Uchida, Hiroki Akiba, Chin-Yu Lin, Masaru Ikegami, et al.. Improved brain expression of anti-amyloid β scFv by complexation of mRNA including a secretion sequence with PEG-based block catiomer. Current Alzheimer Research, Bentham Science Publishers, 2017, 14 (3), pp.295-302. ⟨10.2174/1567205013666161108110031⟩. ⟨hal-02130712⟩
  • Federico Perche, Y. Yi, L. Hespel, P Mi, A Dirisala, et al.. Hydroxychloroquine-conjugated gold nanoparticles for improved siRNA activity. Biomaterials, Elsevier, 2016, 90, pp.62-71. ⟨10.1016/j.biomaterials.2016.02.027⟩. ⟨hal-02130728⟩
  • Chin-Yu Lin, Federico Perche, Masaru Ikegami, Satoshi Uchida, Kazunori Kataoka, et al.. Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles. Journal of Controlled Release, Elsevier, 2016, 235, pp.268-275. ⟨10.1016/j.jconrel.2016.06.001⟩. ⟨hal-02130718⟩
  • Samuel Mussi, Rupa Sawant, Federico Perche, Mônica Oliveira, Ricardo Azevedo, et al.. Novel Nanostructured Lipid Carrier Co-Loaded with Doxorubicin and Docosahexaenoic Acid Demonstrates Enhanced in Vitro Activity and Overcomes Drug Resistance in MCF-7/Adr Cells. Pharmaceutical Research, American Association of Pharmaceutical Scientists, 2014, 31 (8), pp.1882-1892. ⟨10.1007/s11095-013-1290-2⟩. ⟨hal-02130734⟩
  • Federico Perche, S. Biswas, T. Wang, L. Zhu, V. Torchilin. Hypoxia-Targeted siRNA Delivery. Angewandte Chemie International Edition, Wiley-VCH Verlag, 2014, 53 (13), pp.3362-3366. ⟨10.1002/anie.201308368⟩. ⟨hal-02130753⟩
  • Lin Zhu, Federico Perche, Tao Wang, Vladimir Torchilin. Matrix metalloproteinase 2-sensitive multifunctional polymeric micelles for tumor-specific co-delivery of siRNA and hydrophobic drugs. Biomaterials, Elsevier, 2014, 35 (13), pp.4213-4222. ⟨10.1016/j.biomaterials.2014.01.060⟩. ⟨hal-02130742⟩
  • G. Salzano, R. Riehle, G. Navarro, Federico Perche, G. de Rosa, et al.. Polymeric micelles containing reversibly phospholipid-modified anti-survivin siRNA: A promising strategy to overcome drug resistance in cancer. Cancer Letters, Elsevier, 2014, 343 (2), pp.224-231. ⟨10.1016/j.canlet.2013.09.037⟩. ⟨hal-02130786⟩
  • Federico Perche, Vladimir Torchilin. Cancer cell spheroids as a model to evaluate chemotherapy protocols. Cancer Biology and Therapy, Taylor & Francis, 2014, 13 (12), pp.1205-1213. ⟨10.4161/cbt.21353⟩. ⟨hal-02130815⟩
  • Federico Perche, Vladimir Torchilin. Recent Trends in Multifunctional Liposomal Nanocarriers for Enhanced Tumor Targeting. Journal of Drug Delivery, Hindawi Publishing Corporation, 2013, 2013, pp.1-32. ⟨10.1155/2013/705265⟩. ⟨hal-02130868⟩
  • Swati Biswas, Pranali Deshpande, Federico Perche, Namita Dodwadkar, Shailendra Sane, et al.. Octa-arginine-modified pegylated liposomal doxorubicin: An effective treatment strategy for non-small cell lung cancer. Cancer Letters, Elsevier, 2013, 335 (1), pp.191-200. ⟨10.1016/j.canlet.2013.02.020⟩. ⟨hal-02130808⟩
  • Lin Zhu, Tao Wang, Federico Perche, Anton Taigind, Vladimir Torchilin. Enhanced anticancer activity of nanopreparation containing an MMP2-sensitive PEG-drug conjugate and cell-penetrating moiety. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2013, 110 (42), pp.17047-17052. ⟨10.1073/pnas.1304987110⟩. ⟨hal-02130803⟩
  • Federico Perche, Olivier Lambert, Mathieu Berchel, Paul-Alain Jaffres, Chantal Pichon, et al.. Gene transfer by histidylated lipopolyplexes: A dehydration method allowing preservation of their physicochemical parameters and transfection efficiency.. International Journal of Pharmaceutics, Elsevier, 2012, 423 (1), pp.144-50. ⟨10.1016/j.ijpharm.2011.04.009⟩. ⟨hal-00726238⟩
  • Federico Perche, Niravkumar Patel, Vladimir Torchilin. Accumulation and toxicity of antibody-targeted doxorubicin-loaded PEG–PE micelles in ovarian cancer cell spheroid model. Journal of Controlled Release, Elsevier, 2012, 164 (1), pp.95-102. ⟨10.1016/j.jconrel.2012.09.003⟩. ⟨hal-02130810⟩
  • Federico Perche, Thierry Benvegnu, Mathieu Berchel, Loic Lebegue, Chantal Pichon, et al.. Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA.. Nanomedicine: Nanotechnology, Biology and Medicine, Elsevier, 2011, 7 (4), pp.445-53. ⟨10.1016/j.nano.2010.12.010⟩. ⟨hal-00754373⟩
  • Federico Perche, David Gosset, Mathieu Mével, Marie-Laure Miramon, Jean-Jacques Yaouanc, et al.. Selective gene delivery in dendritic cells with mannosylated and histidylated lipopolyplexes.. Journal of Drug Targeting, Informa Healthcare, 2011, 19 (5), pp.315-25. ⟨10.3109/1061186X.2010.504262⟩. ⟨hal-00753554⟩

Chapitre d'ouvrage

  • Federico Perche, Swati Biswas, Niravkumar Patel, Vladimir Torchilin. Hypoxia-Responsive Copolymer for siRNA Delivery. Methods Molecular Biology, 1372, pp.139-162, 2016, ⟨10.1007/978-1-4939-3148-4_12⟩. ⟨hal-02130872⟩
  • Federico Perche, S. Biswas, V. Torchilin. Stimuli-Sensitive Polymeric Nanomedicines for Cancer Imaging and Therapy. Handbook of polymers for pharmaceutical technologies, John Wiley & Sons, Inc., pp.311-344, 2015. ⟨hal-02130886⟩

Brevet

  • Vladimir Torchilin, Swati Biswas, Federico Perche. HYPOXIA-TARGETED DELIVERY SYSTEM FOR PHARMACEUTICAL AGENTS. France, Patent n° : WO2015061321. 2015. ⟨hal-02130900⟩
  • L. Zhu, Federico Perche, Vladimir Torchilin. COPOLYMERS FOR THE DELIVERY OF DRUGS INTO CELLS. France, Patent n° : WO2014085579. 2014. ⟨hal-02130892⟩

Thèse

  • Federico Perche. Transfert d'ARNm par des lipopolyplexes et vaccination antimélanome : ciblage des cellules dendritiques à l'aide de lipopolyplexes mannosylés. Médecine humaine et pathologie. Université d'Orléans, 2010. Français. ⟨NNT : 2010ORLE2068⟩. ⟨tel-00665118⟩

PICHON Chantal

email : chantal.pichon@cnrs-orleans.fr

Téléphone : 02.38.25.55.95

Bureau A216

Professeur, coordinatrice de l’équipe “Biologie cellulaire, cibles moléculaires et thérapies innovantes”, co-responsable du groupe thématique “Biologie de l’ARN et ARN thérapeutiques” et co-responsable du groupe thématique “Biologie de la peau”



154 documents

Article dans une revue

  • Jean-Pierre Gomez, Guillaume Tresset, Chantal Pichon, Patrick Midoux. Improved histidinylated lPEI polyplexes for skeletal muscle cells transfection. International Journal of Pharmaceutics, Elsevier, 2019, 559, pp.58-67. ⟨10.1016/j.ijpharm.2019.01.003⟩. ⟨hal-02067297⟩
  • Phila Raharivelomanana, Jean-Luc Ansel, Elise Lupo, Lily Mijouin, Samuel Guillot, et al.. Tamanu oil and skin active properties: from traditional to modern cosmetic uses. Ocl-Oilseeds and Fats Crops and Lipids, 2018. ⟨hal-01966367⟩
  • Yohann Corvis, Simona Manta, Caroline Thébault, Olivier Couture, Hélène Dhotel, et al.. Novel Perfluorinated Triblock Amphiphilic Copolymers for Lipid-Shelled Microbubble Stabilization. Langmuir, American Chemical Society, 2018, 34 (33), pp.9744-9753. ⟨10.1021/acs.langmuir.8b01668⟩. ⟨hal-02123140⟩
  • Vinodini Vijayarangan, Anthony Delalande, Sébastien Dozias, Jean-Michel Pouvesle, Chantal Pichon, et al.. Cold Atmospheric Plasma Parameters Investigation for Efficient Drug Delivery in HeLa Cells. IEEE Transactions on Radiation and Plasma Medical Sciences, IEEE, 2018, 2 (2), pp.109-115. ⟨hal-01940672⟩
  • Kevin Van Der Jeught, Stefaan de Koker, Lukasz Bialkowski, Carlo Heirman, Patrick Tjok Joe, et al.. Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety. ACS Nano, American Chemical Society, 2018, 12 (10), pp.9815-9829. ⟨https://pubs.acs.org/doi/10.1021/acsnano.8b00966⟩. ⟨10.1021/acsnano.8b00966⟩. ⟨hal-01889829⟩
  • Philippe Michaud, Mouna Dammak, Bilel Hadrich, Mohamed Barkallah, Faiez Hentati, et al.. Modelling Tetraselmis sp. growth-kinetics and optimizing bioactive-compound production through environmental conditions. Bioresource Technology, Elsevier, 2018, 249, pp.510 - 518. ⟨10.1016/j.biortech.2017.10.028⟩. ⟨hal-01657730⟩
  • A. Le Moignic, V. Malard, T. Benvegnu, L. Lemiègre, Mathieu Berchel, et al.. Preclinical evaluation of mRNA trimannosylated lipopolyplexes as therapeutic cancer vaccines targeting dendritic cells. Journal of Controlled Release, Elsevier, 2018, 278, pp.110 - 121. ⟨https://www.sciencedirect.com/science/article/pii/S0168365918301743?via%3Dihub⟩. ⟨10.1016/j.jconrel.2018.03.035⟩. ⟨hal-01774851⟩
  • Mathieu Berchel, Sohail Akhter, Wilfried Berthe, Cristine Gonçalvez, Marine Dubuisson, et al.. Synthesis of α-amino-lipophosphonates as cationic lipids or co-lipids for DNA transfection in dendritic cells. Journal of materials chemistry‎ B, Royal Society of Chemistry, 2017, J. Mater. Chem. B, pp.6869-6881 ⟨http://pubs.rsc.org/en/Content/ArticleLanding/2017/TB/C7TB01080J#!divAbstract⟩. ⟨10.1039/C7TB01080J⟩. ⟨hal-01551638⟩
  • Javed Ahmad, Sohail Akhter, Md. Rizwanullah, Mohammad Ahmed Khan, Lucie Pigeon, et al.. Nanotechnology Based Theranostic Approaches in Alzheimer's Disease Management: Current Status and Future Perspective. Current Alzheimer Research, Bentham Science Publishers, 2017, 14 (11), ⟨10.2174/1567205014666170508121031⟩. ⟨hal-02068674⟩
  • Javed Ahmad, Madhur Singhal, Saima Amin, Md. Rizwanullah, Sohail Akhter, et al.. Bile Salt Stabilized Vesicles (Bilosomes): A Novel Nano-Pharmaceutical Design for Oral Delivery of Proteins and Peptides. Current Pharmaceutical Design, Bentham Science Publishers, 2017, 23 (11), pp.1575 - 1588. ⟨10.2174/1381612823666170124111142⟩. ⟨hal-01656515⟩
  • Viorel Simion, Wissem Deraredj Nadim, Hélène Bénédetti, Chantal Pichon, Séverine Morisset-Lopez, et al.. Pharmacomodulation of microRNA Expression in Neurocognitive Diseases: Obstacles and Future Opportunities. Current Neuropharmacology, Bentham Science Publishers, 2017, 15 (2), pp.276 - 290. ⟨10.2174/1570159X14666160630210422⟩. ⟨hal-01618771⟩
  • Wissem Deraredj Nadim, Simion Viorel, Hélène Bénédetti, Chantal Pichon, Patrick Baril, et al.. MicroRNAs in Neurocognitive Dysfunctions: New Molecular Targets for Pharmacological Treatments?. Current Neuropharmacology, Bentham Science Publishers, 2017, 15 (2), pp.260 - 275. ⟨10.2174/1570159X14666160709001441⟩. ⟨hal-01618199⟩
  • Faten Ben Amor, Fatma Elleuch, Hajer Ben Hlima, Matthieu Garnier, Bruno Saint-Jean, et al.. Proteomic Analysis of the Chlorophyta Dunaliella New Strain AL-1 Revealed Global Changes of Metabolism during High Carotenoid Production. Marine drugs, MDPI, 2017, 15 (9), pp.293. ⟨10.3390/md15090293⟩. ⟨hal-02135151⟩
  • Sarwar Beg, Mahfoozur Rahman, Atul Jain, Sumant Saini, Patrick Midoux, et al.. Nanoporous metal organic frameworks as hybrid polymer–metal composites for drug delivery and biomedical applications. Drug Discovery Today Biosilico, Elsevier, 2017, 22 (4), pp.625-637. ⟨10.1016/j.drudis.2016.10.001⟩. ⟨hal-02068701⟩
  • Patrick Midoux, Lucie Pigeon, Cristine Goncalves, Chantal Pichon. Peptides mediating DNA transport on microtubules and their impact on non-viral gene transfer efficiency. Bioscience Reports, Portland Press, 2017, 37 (5), pp.BSR20170995. ⟨10.1042/BSR20170995⟩. ⟨hal-02068759⟩
  • Anthony Delalande, Colette Bastié, Lucie Pigeon, Simona Manta, Matthias Lebertre, et al.. Cationic gas-filled microbubbles for ultrasound-based nucleic acids delivery. Bioscience Reports, Portland Press, 2017, 37 (6), pp.BSR20160619. ⟨10.1042/BSR20160619⟩. ⟨hal-02123147⟩
  • Thomas Démoulins, Pavlos C Englezou, Panagiota Milona, Nicola Ruggli, Nicola Tirelli, et al.. Self-Replicating RNA Vaccine Delivery to Dendritic Cells.. Methods in Molecular Biology, Humana Press/Springer Imprint, 2017, pp.37-75. ⟨10.1007/978-1-4939-6481-9_3⟩. ⟨hal-01656568⟩
  • Samuel Guillot, Fabienne Meducin, Kristina Poljak, Virginie Malard, Alexandra Foucault-Collet, et al.. Nanostructured monolinolein miniemulsions as delivery systems: Role of the internal mesophase on cytotoxicity and cell internalization. International Journal of Pharmaceutics, Elsevier, 2017, 523 (1), pp.142 - 150. ⟨10.1016/j.ijpharm.2017.03.012⟩. ⟨hal-01656547⟩
  • Reine Nehmé, Carla Atieh, Syntia Fayad, Bérengère Claude, Agnès Chartier, et al.. Microalgae amino acid extraction and analysis at nanomolar level using electroporation and capillary electrophoresis with laser-induced fluorescence detection. Journal of Separation Science, Wiley-VCH Verlag, 2017, 40 (2), pp.558 - 566. ⟨10.1002/jssc.201601005⟩. ⟨hal-01618682⟩
  • Florence Abdallah, Lily Mijouin, Chantal Pichon. Skin Immune Landscape: Inside and Outside the Organism. Mediators of Inflammation, Hindawi Publishing Corporation, 2017, 2017, pp.1 - 17. ⟨10.1155/2017/5095293⟩. ⟨hal-01622500⟩
  • Cristine Gonçalves, Pierre Gomez, William Même, Bazoly Rasolonjatovo, David Gosset, et al.. Curcumin/poly(2-methyl-2-oxazoline-b-tetrahydrofuran-b-2-methyl-2-oxazoline) formulation: An improved penetration and biological effect of curcumin in F508del-CFTR cell lines. European Journal of Pharmaceutics and Biopharmaceutics, Elsevier, 2017, 117, pp.168-181. ⟨10.1016/j.ejpb.2017.04.015⟩. ⟨hal-01618274⟩
  • Vítor Gaspar, Carla Cruz, João A. Queiroz, Chantal Pichon, Ilídio J. Correia, et al.. Highly selective capture of minicircle DNA biopharmaceuticals by a novel zinc-histidine peptide conjugate. Separation and Purification Technology, Elsevier, 2017, 174 (26), pp.417 - 424. ⟨10.1016/j.seppur.2016.10.054⟩. ⟨hal-01618255⟩
  • Jean-Pierre Gomez, Cristine Gonçalves, Chantal Pichon, Patrick Midoux. Effect of IL-1β, TNF-α and IGF-1 on trans-endothelial passage of synthetic vectors through an in vitro vascular endothelial barrier of striated muscle. Gene Therapy, Nature Publishing Group, 2017, 24 (7), pp.416 - 424. ⟨10.1038/gt.2017.40⟩. ⟨hal-01618260⟩
  • Viorel Simion, Julien Sobilo, Rudy Clemoncon, Sharuja Natkunarajah, Safia Ezzine, et al.. Positive radionuclide imaging of miRNA expression using RILES and the human sodium iodide symporter as reporter gene is feasible and supports a protective role of miRNA-23a in response to muscular atrophy. PLoS ONE, Public Library of Science, 2017, 12 (5), ⟨10.1371/journal.pone.0177492⟩. ⟨hal-01618769⟩
  • Thomas Thibault, Jéril Degrouard, Patrick Baril, Chantal Pichon, Patrick Midoux, et al.. Production of DNA minicircles less than 250 base pairs through a novel concentrated DNA circularization assay enabling minicircle design with NF-κB inhibition activity. Nucleic Acids Research, Oxford University Press, 2017, 45 (5), pp.e26 - e26. ⟨10.1093/nar/gkw1034⟩. ⟨hal-01618796⟩
  • Syntia Fayad, Reine Nehmé, Mona Tannoury, Eric Lesellier, Chantal Pichon, et al.. Macroalga Padina pavonica water extracts obtained by pressurized liquid extraction and microwave-assisted extraction inhibit hyaluronidase activity as shown by capillary electrophoresis. Journal of Chromatography A, Elsevier, 2017, 1497, pp.19 - 27. ⟨10.1016/j.chroma.2017.03.033⟩. ⟨hal-01618229⟩
  • Simona Manta, Gilles Renault, Anthony Delalande, Olivier Couture, Isabelle Lagoutte, et al.. Cationic microbubbles and antibiotic-free miniplasmid for sustained ultrasound–mediated transgene expression in liver. Journal of Controlled Release, Elsevier, 2017, 262, pp.170 - 181. ⟨10.1016/j.jconrel.2017.07.015⟩. ⟨hal-01656574⟩
  • Javed Ahmad, Sohail Akhter, Mohammad Ahmed Khan, Muhammad Wahajuddin, Nigel H. Greig, et al.. Engineered Nanoparticles Against MDR in Cancer: The State of the Art and its Prospective. Current Pharmaceutical Design, Bentham Science Publishers, 2016, 22 (28), pp.4360-4373. ⟨10.2174/1381612822666160617112111⟩. ⟨hal-02068807⟩
  • Capucine Bourgeois, Émilie A. Leclerc, Cyrielle Corbin, Joël Doussot, Valérie Serrano, et al.. Nettle (Urtica dioica L.) as a source of antioxidant and anti-aging phytochemicals for cosmetic applications. Comptes Rendus Chimie, Elsevier Masson, 2016, 19 (9), pp.1090-1100. ⟨10.1016/j.crci.2016.03.019⟩. ⟨hal-01607310⟩
  • Cristine Goncalves, Sohail Akhter, Chantal Pichon, Patrick Midoux. Intracellular Availability of pDNA and mRNA after Transfection: A Comparative Study among Polyplexes, Lipoplexes, and Lipopolyplexes. Molecular Pharmaceutics, American Chemical Society, 2016, 13 (9), pp.3153-3163. ⟨10.1021/acs.molpharmaceut.6b00376⟩. ⟨hal-02069071⟩
  • Rea Bingula, Carmen Dupuis, Chantal Pichon, Jean-Yves Berthon, Marc Filaire, et al.. Study of the Effects of Betaine and/or C-Phycocyanin on the Growth of Lung Cancer A549 Cells In Vitro and In Vivo. Journal of Oncology, Hindawi Publishing Corporation, 2016, 2016, pp.1-11. ⟨10.1155/2016/8162952⟩. ⟨hal-02068827⟩
  • Thomas Démoulins, Panagiota Milona, Pavlos C. Englezou, Thomas Ebensen, Kai Schulze, et al.. Polyethylenimine-based polyplex delivery of self-replicating RNA vaccines. Nanomedicine: Nanotechnology, Biology and Medicine, Elsevier, 2016, 12 (3), pp.711 - 722. ⟨10.1016/j.nano.2015.11.001⟩. ⟨hal-01406947⟩
  • Simona Manta, Anthony Delalande, Michel Bessodes, Michel Francis Bureau, Daniel Scherman, et al.. Characterization of Positively Charged Lipid Shell Microbubbles with Tunable Resistive Pulse Sensing (TRPS) Method: A Technical Note. Ultrasound in Medicine and Biology, Elsevier, 2016, 42 (2), pp.624 - 630. ⟨10.1016/j.ultrasmedbio.2015.10.010⟩. ⟨hal-01407496⟩
  • Chloe Leduc, Lauren Sobilo, Hechmi Toumi, Philippe Mondon, Eric Lespessailles, et al.. TGF-beta-induced early gene-1 overexpression promotes oxidative stress protection and actin cytoskeleton rearrangement in human skin fibroblasts. Biochimica et Biophysica Acta:Biomembranes, Elsevier, 2016, 1860 (6), pp.1071 - 1078. ⟨10.1016/j.bbagen.2016.02.009⟩. ⟨hal-01407918⟩
  • Patrick Baril, Chantal Pichon. Positive Bioluminescence Imaging of MicroRNA Expression in Small Animal Models Using an Engineered Genetic-Switch Expression System, RILES.. Methods in Molecular Biology, Humana Press/Springer Imprint, 2016, 1372, pp.193-208. ⟨hal-01405832⟩
  • Ludovic Gaut, Nicolas Robert, Antony Delalande, Marie-Ange Bonnin, Chantal Pichon, et al.. EGR1 Regulates Transcription Downstream of Mechanical Signals during Tendon Formation and Healing. PLoS ONE, Public Library of Science, 2016, 11 (11), pp. e0166237. ⟨10.1371/journal.pone.0166237.t001⟩. ⟨hal-01394467⟩
  • Phila Raharivelomanana, Jean-Luc Ansel, E. Lupo, L. Mijouin, S. Guillot, et al.. Biological activity of Polynesian Calophyllum inophyllum oil extract on human skin cells. Planta Medica, Georg Thieme Verlag, 2016, 82 (11-12), p. 961-966. ⟨10.1055/s-0042-108205⟩. ⟨hal-01592246⟩
  • L. Pigeon, C. GonÇalves, C. Pichon, P. Midoux. Evidence for plasmid DNA exchange after polyplex mixing. Soft Matter, Royal Society of Chemistry, 2016, 12 (33), pp.7012-7019. ⟨10.1039/c6sm00575f⟩. ⟨hal-02069106⟩
  • Nihed Ben Halima, Bassem Khemakhem, Imen Fendri, Hiroyuki Ogata, Patrick Baril, et al.. Identification of a new oat β-amylase by functional proteomics. Biochimica et Biophysica Acta Proteins and Proteomics, Elsevier, 2016, 1864 (1), pp.52 - 61. ⟨10.1016/j.bbapap.2015.10.001⟩. ⟨hal-01405835⟩
  • J. Barbeau, L. Lemiègre, A. Quelen, V. Malard, H. Gao, et al.. Synthesis of a trimannosylated-equipped archaeal diether lipid for the development of novel glycoliposomes. Carbohydrate Research, Elsevier, 2016, 435, pp.142--148. ⟨10.1016/j.carres.2016.10.003⟩. ⟨hal-01398046⟩
  • Vítor Gaspar, André F. Moreira, Elisabete C. Costa, João A. Queiroz, Fani Sousa, et al.. Gas-generating TPGS-PLGA microspheres loaded with nanoparticles (NIMPS) for co-delivery of minicircle DNA and anti-tumoral drugs. Colloids and Surfaces B: Biointerfaces, Elsevier, 2015, 134, pp.287 - 294. ⟨10.1016/j.colsurfb.2015.07.004⟩. ⟨hal-01657427⟩
  • Anthony Delalande, Chloe Leduc, Patrick Midoux, Michiel Postema, Chantal Pichon. Efficient Gene Delivery by Sonoporation Is Associated with Microbubble Entry into Cells and the Clathrin-Dependent Endocytosis Pathway. Ultrasound in Medicine and Biology, Elsevier, 2015, 41 (7), pp.1913-1926. ⟨10.1016/j.ultrasmedbio.2015.03.010⟩. ⟨hal-02072234⟩
  • Mahfoozur Rahman, Sohail Akhter, Mohammad Zaki Ahmad, Javed Ahmad, Richard Addo, et al.. Emerging advances in cancer nanotheranostics with graphene nanocomposites: opportunities and challenges. Nanomedicine, Future Medicine, 2015, 10 (15), pp.2405-2422. ⟨10.2217/nnm.15.68⟩. ⟨hal-02072297⟩
  • Agnieszka Jazwa, Mateusz Stoszko, Mateusz Tomczyk, Karolina Bukowska-Strakova, Chantal Pichon, et al.. HIF-regulated HO-1 gene transfer improves the post-ischemic limb recovery and diminishes TLR-triggered immune responses — Effects modified by concomitant VEGF overexpression. Vascular Pharmacology, Elsevier, 2015, 71, pp.127-138. ⟨10.1016/j.vph.2015.02.011⟩. ⟨hal-02072271⟩
  • Magdalena Tertil, Slawomir Golda, Klaudia Skrzypek, Urszula Florczyk, Kazimierz Weglarczyk, et al.. Nrf2-heme oxygenase-1 axis in mucoepidermoid carcinoma of the lung: Antitumoral effects associated with down-regulation of matrix metalloproteinases. Free Radical Biology and Medicine, Elsevier, 2015, 89, pp.147-157. ⟨10.1016/j.freeradbiomed.2015.08.004⟩. ⟨hal-01657418⟩
  • Anthony Delalande, Marie-Pierre Gosselin, Arnaud Suwalski, William Guilmain, Chloé Leduc, et al.. Enhanced Achilles tendon healing by fibromodulin gene transfer. Nanomedicine: Nanotechnology, Biology and Medicine, Elsevier, 2015, 11 (7), pp.1735 - 1744. ⟨http://www.nanomedjournal.com/article/S1549-9634%2815%2900119-7/abstract⟩. ⟨10.1016/j.nano.2015.05.004⟩. ⟨hal-01537597⟩
  • Jean-Luc Ansel, Jean-Francois Butaud, M. Nicolas, G. Lecellier, Chantal Pichon, et al.. Le "Tamanu" et ses propriétés en dermocosmétique. La Phytothérapie Européenne, 2015. ⟨hal-01197430⟩
  • Magdalena Wytrwal, Chloe Leduc, Michal Sarna, Cristine Goncalves, Mariusz Kepczynski, et al.. Gene delivery efficiency and intracellular trafficking of novel poly(allylamine) derivatives. International Journal of Pharmaceutics, Elsevier, 2015, 478 (1), pp.372-382. ⟨10.1016/j.ijpharm.2014.11.053⟩. ⟨hal-01172009⟩
  • Nawal Belmadi, Patrick Midoux, Pascal Loyer, Catherine Passirani, Chantal Pichon, et al.. Synthetic vectors for gene delivery: An overview of their evolution depending on routes of administration. Biotechnology Journal, Wiley-VCH Verlag, 2015, 10 (9), pp.1370-1389. ⟨10.1002/biot.201400841⟩. ⟨hal-01162373⟩
  • Vítor M. Gaspar, Elisabete C. Costa, João A. Queiroz, Chantal Pichon, Fani Sousa, et al.. Folate-Targeted Multifunctional Amino Acid-Chitosan Nanoparticles for Improved Cancer Therapy. Pharmaceutical Research, American Association of Pharmaceutical Scientists, 2015, 32 (2), pp.562-577. ⟨10.1007/s11095-014-1486-0⟩. ⟨hal-01171243⟩
  • Patrick Midoux, Chantal Pichon. Lipid-based mRNA vaccine delivery systems. Expert Review of Vaccines, Expert Reviews (formerly Future Drugs), 2015, 14 (2), pp.221-234. ⟨10.1586/14760584.2015.986104⟩. ⟨hal-01171750⟩
  • Vítor Gaspar, Duarte De Melo-Diogo, Elisabete Costa, André Moreira, João Queiroz, et al.. Minicircle DNA vectors for gene therapy: advances and applications. Expert Opinion on Biological Therapy, Informa Healthcare, 2015, 15 (3), pp.353-379. ⟨10.1517/14712598.2015.996544⟩. ⟨hal-01171236⟩
  • Patrick Baril, Safia Ezzine, Chantal Pichon. Monitoring the Spatiotemporal Activities of miRNAs in Small Animal Models Using Molecular Imaging Modalities. International Journal of Molecular Sciences, MDPI, 2015, 16 (3), pp.4947-4972. ⟨10.3390/ijms16034947⟩. ⟨hal-01170451⟩
  • Vítor Gaspar, Elisabete C. Costa, Duarte de Melo-Diogo, Frédéric Foucher, João A. Queiroz, et al.. Bioreducible poly(2-ethyl-2-oxazoline)–PLA–PEI-SS triblock copolymer micelles for co-delivery of DNA minicircles and Doxorubicin. Journal of Controlled Release, Elsevier, 2015, 213 (7), pp.175 - 191. ⟨10.1016/j.jconrel.2015.07.011⟩. ⟨hal-01657388⟩
  • Nihed Ben Halima, Maha Borchani, Imen Fendri, Bassem Khemakhem, David Gosset, et al.. Optimised amylases extraction from oat seeds and its impact on bread properties.. International Journal of Biological Macromolecules, Elsevier, 2015, 72, pp.1213-1221. ⟨10.1016/j.ijbiomac.2014.10.018⟩. ⟨hal-01170470⟩
  • Delphine B Maurel, Delphine Benaitreau, Christelle Jaffré, Hechmi Toumi, Hugues Portier, et al.. Effect of the alcohol consumption on osteocyte cell processes: a molecular imaging study.. Journal of Cellular and Molecular Medicine, Wiley Open Access, 2014, 18 (8), pp.1680-1693. ⟨hal-01179388⟩
  • Tristan Montier, Chantal Pichon, Marc Blondel, Patrick Midoux. Editorial: Current status and prospects on nucleic acid transfer. Biotechnology Journal, Wiley-VCH Verlag, 2014, 9 (11), pp.1363-1364. ⟨10.1002/biot.201300510⟩. ⟨hal-02135170⟩
  • David Brevet, Ouahiba Hocine, Anthony Delalande, Laurence Raehm, Clarence Charnay, et al.. Improved gene transfer with histidine-​functionalized mesoporous silica nanoparticles. International Journal of Pharmaceutics, Elsevier, 2014, pp.197-205. ⟨10.1016/j.ijpharm.2014.05.020⟩. ⟨hal-01068026⟩
  • Benoit Maury, Cristine Gonçalves, Guillaume Tresset, Mehdi Zeghal, Hervé Cheradame, et al.. Influence of pDNA availability on transfection efficiency of polyplexes in non-proliferative cells.. Biomaterials, Elsevier, 2014, 35 (22), pp.5977-5985. ⟨10.1016/j.biomaterials.2014.04.007⟩. ⟨hal-01179393⟩
  • Nihed Ben Halima, Ahlem Ben Slima, Imen Moalla, Hamadi Fetoui, Chantal Pichon, et al.. Protective effects of oat oil on deltamethrin-induced reprotoxicity in male mice. Food and Function, Cambridge : Royal Society of Chemistry, 2014, 5 (9), pp.2070-2077. ⟨10.1039/c4fo00190g⟩. ⟨hal-01175499⟩
  • Ulysse Asseline, Cristine Gonçalves, Chantal Pichon, Patrick Midoux. Improved nuclear delivery of antisense 2′-Ome RNA by conjugation with the histidine-rich peptide H5WYG. The Journal of Gene Medicine, Wiley, 2014, 16 (7-8), pp.157-165. ⟨10.1002/jgm.2773⟩. ⟨hal-01175483⟩
  • Magdalena Tertil, Klaudia Skrzypek, Urszula Florczyk, Kazimierz Weglarczyk, Halina Was, et al.. Regulation and novel action of thymidine phosphorylase in non-small cell lung cancer: crosstalk with Nrf2 and HO-1.. PLoS ONE, Public Library of Science, 2014, 9 (5), pp.e97070. ⟨hal-01181117⟩
  • Cristine Gonçalves, Mathieu Berchel, Marie-Pierre Gosselin, Virginie Malard, Hervé Cheradame, et al.. Lipopolyplexes comprising imidazole/imidazolium lipophosphoramidate, histidinylated polyethyleneimine and siRNA as efficient formulation for siRNA transfection. International Journal of Pharmaceutics, Elsevier, 2014, 460 (1-2), pp.264-272. ⟨10.1016/j.ijpharm.2013.11.005⟩. ⟨hal-01179049⟩
  • Dragomira Majhen, Nikolina Stojanović, Dunja Vukić, Chantal Pichon, Chloé Leduc, et al.. Increased adenovirus Type 5 mediated transgene expression due to RhoB down-regulation.. PLoS ONE, Public Library of Science, 2014, 9 (1), pp.e86698. ⟨hal-01179347⟩
  • Vítor M. Gaspar, Cristine Gonçalves, Duarte de Melo-Diogo, Elisabete C. Costa, João A. Queiroz, et al.. Poly(2-ethyl-2-oxazoline)–PLA-g–PEI amphiphilic triblock micelles for co-delivery of minicircle DNA and chemotherapeutics. Journal of Controlled Release, Elsevier, 2014, 189, pp.90-104. ⟨10.1016/j.jconrel.2014.06.040⟩. ⟨hal-01179020⟩
  • Vítor M. Gaspar, Cláudio J. Maia, João A. Queiroz, Chantal Pichon, Ilídio J. Correia, et al.. Improved Minicircle DNA Biosynthesis for Gene Therapy Applications. Human gene therapy methods, New Rochelle, NY : Mary Ann Liebert, 2014, 25 (2), pp.93-105. ⟨10.1089/hgtb.2013.020⟩. ⟨hal-01179002⟩
  • Julie Orio, Elisabeth Bellard, Houda Baaziz, Chantal Pichon, Peter Mouritzen, et al.. Sub-cellular temporal and spatial distribution of electrotransferred LNA/DNA oligomer.. Journal of RNAi and Gene Silencing, Library Publishing Media, 2013, 9, pp.479-85. ⟨hal-02071795⟩
  • Isabelle Krolikiewicz-Renimel, Thomas Michel, Emilie Destandau, Madhukar Reddy, Patrice André, et al.. Protective effect of a Butea monosperma (Lam.) Taub. flowers extract against skin inflammation: Antioxidant, anti-inflammatory and matrix metalloproteinases inhibitory activities. Journal of Ethnopharmacology, Elsevier, 2013, 148 (2), pp.537-543. ⟨10.1016/j.jep.2013.05.001⟩. ⟨hal-02070877⟩
  • Sara Lacerda, Célia S Bonnet, Agnès Pallier, Sandrine Villette, Frédéric Foucher, et al.. Lanthanide-Based, Near-Infrared Luminescent and Magnetic Lipoparticles: Monitoring Particle Integrity.. Small, Wiley-VCH Verlag, 2013, 9 (16), pp.2662-2666. ⟨10.1002/smll.201201923⟩. ⟨hal-00817465⟩
  • Solenne Bire, David Gosset, Gwenhael Jegot, Patrick Midoux, Chantal Pichon, et al.. Exogenous mRNA delivery and bioavailability in gene transfer mediated by piggyBac transposition. BMC Biotechnology, BioMed Central, 2013, 13, pp.1-15. ⟨10.1186/1472-6750-13-75⟩. ⟨hal-01129780⟩
  • Lucie Pigeon, Cristine Gonçalves, David Gosset, Chantal Pichon, Patrick Midoux. An E3-14.7K Peptide that Promotes Microtubules-Mediated Transport of Plasmid DNA Increases Polyplexes Transfection Efficiency.. Small, Wiley-VCH Verlag, 2013, 9 (22), pp.3845-3851. ⟨10.1002/smll.201300217⟩. ⟨hal-00840172⟩
  • Safia Ezzine, Georges Vassaux, Bruno Pitard, Benoit Barteau, Jean-Marc Malinge, et al.. RILES, a novel method for temporal analysis of the in vivo regulation of miRNA expression.. Nucleic Acids Research, Oxford University Press, 2013, epub ahead of print. ⟨10.1093/nar/gkt797⟩. ⟨hal-00874881⟩
  • Jean-Pierre Gomez, Chantal Pichon, Patrick Midoux. Ability of plasmid DNA complexed with histidinylated lPEI and lPEI to cross in vitro lung and muscle vascular endothelial barriers. Gene, Elsevier, 2013, 525 (2), pp.182-190. ⟨10.1016/j.gene.2013.03.055⟩. ⟨hal-02070843⟩
  • Anthony Delalande, Spiros Kotopoulis, Michiel Postema, Patrick Midoux, Chantal Pichon. Sonoporation: Mechanistic insights and ongoing challenges for gene transfer. Gene, Elsevier, 2013, 525 (2), pp.191-199. ⟨10.1016/j.gene.2013.03.095⟩. ⟨hal-02070788⟩
  • Vítor Gaspar, Carla Cruz, João Queiroz, Chantal Pichon, Ilídio Correia, et al.. Sensitive Detection of Peptide–Minicircle DNA Interactions by Surface Plasmon Resonance. Analytical Chemistry, American Chemical Society, 2013, 85 (4), pp.2304-2311. ⟨10.1021/ac303288x⟩. ⟨hal-02070840⟩
  • Lynne Rudd, Chantal Pichon, Anthony Delalande. Ultrasound and microbubbles assisted-gene transfer: what is next?. Ultraschall in der Medizin, Georg Thieme Verlag, 2012, 33 (4), pp.391-3. ⟨hal-02071821⟩
  • Anthony Delalande, Michiel Postema, Nathalie Mignet, Patrick Midoux, Chantal Pichon. Ultrasound and microbubble-assisted gene delivery: recent advances and ongoing challenges.. Ther Deliv, 2012, 3 (10), pp.1199-1215. ⟨hal-00817350⟩
  • Federico Perche, Olivier Lambert, Mathieu Berchel, Paul-Alain Jaffres, Chantal Pichon, et al.. Gene transfer by histidylated lipopolyplexes: A dehydration method allowing preservation of their physicochemical parameters and transfection efficiency.. International Journal of Pharmaceutics, Elsevier, 2012, 423 (1), pp.144-50. ⟨10.1016/j.ijpharm.2011.04.009⟩. ⟨hal-00726238⟩
  • Fabienne Godin, Sandrine Villette, Béatrice Vallée, Michel Doudeau, Séverine Morisset-Lopez, et al.. A fraction of neurofibromin interacts with PML bodies in the nucleus of the CCF astrocytoma cell line.. Biochemical and Biophysical Research Communications, Elsevier, 2012, 418 (4), pp.689-94. ⟨10.1016/j.bbrc.2012.01.079⟩. ⟨hal-00721861⟩
  • Ludivine Billiet, Jean-Pierre Gomez, Mathieu Berchel, Paul-Alain Jaffres, Tony Le Gall, et al.. Gene transfer by chemical vectors, and endocytosis routes of polyplexes, lipoplexes and lipopolyplexes in a myoblast cell line.. Biomaterials, Elsevier, 2012, 33 (10), pp.2980-90. ⟨10.1016/j.biomaterials.2011.12.027⟩. ⟨hal-00721795⟩
  • Célia S Bonnet, Frédéric Buron, Fabien Caillé, Chad M Shade, Bohuslav Drahoš, et al.. Pyridine-based lanthanide complexes combining MRI and NIR luminescence activities.. Chemistry - A European Journal, Wiley-VCH Verlag, 2012, 18 (5), pp.1419-31. ⟨10.1002/chem.201102310⟩. ⟨hal-00720541⟩
  • Véronique Bennevault-Celton, Allan Urbach, Olivier Martin, Chantal Pichon, Philippe Guégan, et al.. Supramolecular assemblies of histidinylated α-cyclodextrin in the presence of DNA scaffold during CDplexes formation.. Bioconjugate Chemistry, American Chemical Society, 2011, 22 (12), pp.2404-14. ⟨10.1021/bc200167p⟩. ⟨hal-00720527⟩
  • Federico Perche, Thierry Benvegnu, Mathieu Berchel, Loic Lebegue, Chantal Pichon, et al.. Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA.. Nanomedicine: Nanotechnology, Biology and Medicine, Elsevier, 2011, 7 (4), pp.445-53. ⟨10.1016/j.nano.2010.12.010⟩. ⟨hal-00754373⟩
  • Marie Breton, Jean-François Berret, Claudie Bourgaux, Teresa Kral, Martin Hof, et al.. Protonation of lipids impacts the supramolecular and biological properties of their self-assembly.. Langmuir, American Chemical Society, 2011, 27 (20), pp.12336-45. ⟨10.1021/la202439s⟩. ⟨hal-00720543⟩
  • D. B. Maurel, C. Jaffre, G. Y. Rochefort, P. C. Aveline, Nathalie Boisseau, et al.. Low bone accrual is associated with osteocyte apoptosis in alcohol-induced osteopenia.. BONE, Elsevier, 2011, 49 (3), pp.543-52. ⟨10.1016/j.bone.2011.06.001⟩. ⟨hal-00720676⟩
  • A. Delalande, S. Kotopoulis, T. Rovers, C. Pichon, M. Postema. Sonoporation at low mechanical index. Bubble Science, Engineering & Technology, Francis & Taylor, 2011, 3 (1), pp.3-12. ⟨10.1179/1758897911Y.0000000001⟩. ⟨hal-00608604⟩
  • Emilie Bertrand, Cristine Gonçalves, Ludivine Billiet, Jean Pierre Gomez, Chantal Pichon, et al.. Histidinylated linear PEI: a new efficient non-toxic polymer for gene transfer.. Chemical Communications, Royal Society of Chemistry, 2011, 47 (46), pp.12547-9. ⟨10.1039/c1cc15716g⟩. ⟨hal-00720539⟩
  • Federico Perche, David Gosset, Mathieu Mével, Marie-Laure Miramon, Jean-Jacques Yaouanc, et al.. Selective gene delivery in dendritic cells with mannosylated and histidylated lipopolyplexes.. Journal of Drug Targeting, Informa Healthcare, 2011, 19 (5), pp.315-25. ⟨10.3109/1061186X.2010.504262⟩. ⟨hal-00753554⟩
  • Anthony Delalande, Ayache Bouakaz, Gilles Renault, Flore Tabareau, Spiros Kotopoulis, et al.. Ultrasound and microbubble-assisted gene delivery in Achilles tendons: long lasting gene expression and restoration of fibromodulin KO phenotype.. Journal of Controlled Release, Elsevier, 2011, 156 (2), pp.223-30. ⟨10.1016/j.jconrel.2011.08.020⟩. ⟨hal-00720602⟩
  • Chantal Pichon, Ludivine Billiet, Patrick Midoux. Chemical vectors for gene delivery: uptake and intracellular trafficking. Current Opinion in Biotechnology, Elsevier, 2010, 21 (5), pp.640-645. ⟨10.1016/j.copbio.2010.07.003⟩. ⟨hal-00602488⟩
  • K. Kaddur, L. Lebegue, F. Tranquart, P. Midoux, C. Pichon, et al.. Transient transmembrane release of green fluorescent proteins with sonoporation. IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, Institute of Electrical and Electronics Engineers, 2010, 57 (7), pp.1558-1567. ⟨10.1109/TUFFC.2010.1586⟩. ⟨hal-00529340⟩
  • Matthieu Fisichella, Hinda Dabboue, Sanjib Bhattacharyya, Gerald Lelong, Marie-Louise Saboungi, et al.. Uptake of Functionalized Mesoporous Silica Nanoparticles by Human Cancer Cells. Journal of Nanoscience and Nanotechnology, American Scientific Publishers, 2010, 10 (4), pp.314-2324. ⟨10.1166/jnn.2010.1917⟩. ⟨hal-00529333⟩
  • Jean Doucet, Fatma Briki, Aurélien Gourrier, Chantal Pichon, Laurie Gumez, et al.. Modeling the lateral organization of collagen molecules in fibrils using the paracrystal concept. Journal of Structural Biology, Elsevier, 2010, 173 (2), pp.197 - 201. ⟨10.1016/j.jsb.2010.11.018⟩. ⟨hal-01391584⟩
  • Anthony Delalande, Michel-Francis Bureau, Patrick Midoux, Ayache Bouakaz, Chantal Pichon. Ultrasound-assisted microbubbles gene transfer in tendons for gene therapy. Ultrasonics Sonochemistry, Elsevier, 2010, 50 (2), pp.269-272. ⟨10.1016/j.ultras.2009.09.035⟩. ⟨hal-00529321⟩
  • Marie Breton, Jeanne Leblond, Johanne Seguin, Patrick Midoux, Daniel Scherman, et al.. Comparative gene transfer between cationic and thiourea lipoplexes. The Journal of Gene Medicine, Wiley, 2010, 12 (1), pp.45-54. ⟨10.1002/jgm.1417⟩. ⟨hal-00529308⟩
  • Arnaud Suwalski, Hinda Dabboue, Anthony Delalande, Sabine F. Bensamoun, Francis Canon, et al.. Accelerated Achilles tendon healing by PDGF gene delivery with mesoporous silica nanoparticles. Biomaterials, Elsevier, 2010, 31 (19), pp.5237-5245. ⟨10.1016/j.biomaterials.2010.02.077⟩. ⟨hal-00529475⟩
  • L. Gumez, S.F. Bensamoun, J. Doucet, O. Haddad, J.R. Hawse, et al.. Molecular structure of tail tendon fibers in TIEG1 knockout mice using synchrotron diffraction technology. Journal of Applied Physiology, American Physiological Society, 2010, 108 (6), pp.1706-1710. ⟨10.1152/japplphysiol.00356.2010⟩. ⟨hal-00624395⟩
  • Cristine Gonçalves, Marie-Yvonne Ardourel, Martine Decoville, Gilles Breuzard, Patrick Midoux, et al.. An optimized extended DNA kappa B site that enhances plasmid DNA nuclear import and gene expression. The Journal of Gene Medicine, Wiley, 2009, 11 (5), pp.401-411. ⟨10.1002/jgm.1312⟩. ⟨hal-00522437⟩
  • Corinne Bure, Régine Maget, Agnès F. Delmas, Chantal Pichon, Patrick Midoux. Histidine-rich peptide: evidence for a single zinc-binding site on H5WYG peptide that promotes membrane fusion at neutral pH. Journal of Mass Spectrometry, Wiley-Blackwell, 2009, 44 (1), pp.81-89. ⟨10.1002/jms.1473⟩. ⟨hal-00521834⟩
  • Patrick Midoux, Chantal Pichon, Jean-Jacques Yaouanc, Paul-Alain Jaffres. Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers. British Journal of Pharmacology, Wiley, 2009, 157 (2), pp.166-178. ⟨10.1111/j.1476-5381.2009.00288.x⟩. ⟨hal-00525108⟩
  • Corinne Bure, Chantal Pichon, Patrick Midoux. Involvement of histidines 11, 15 and 19 in the binding of zinc to the fusogenic H5WYG peptide. Journal of Mass Spectrometry, Wiley-Blackwell, 2009, 44 (8), pp.1163-1170. ⟨10.1002/jms.1591⟩. ⟨hal-00521851⟩
  • S. Bensamoun, L. Gumez, J. Hawse, M. Subramaniam, F. Briki, et al.. Comparison of tendon fiber structures between wild type and TIEG knockout mice using synchrotron microdiffraction. Computer Methods in Biomechanics and Biomedical Engineering, London : Informa Healthcare, 2008, 11 (sup001), pp.29 - 30. ⟨10.1080/10255840802296889⟩. ⟨hal-01391846⟩
  • Patrick Midoux, Gilles Breuzard, Jean-Pierre Gomez, Chantal Pichon. Polymer-Based Gene Delivery: A Current Review on the Uptake and Intracellular Trafficking of Polyplexes. Current Gene Therapy, Bentham Science Publishers, 2008, 8 (5), pp.335-352. ⟨hal-00518197⟩
  • Chantal Pichon, Kadija Kaddur, Patrick Midoux, François Tranquart, Ayache Bouakaz. Recent advances in gene delivery with ultrasound and microbubbles. Journal of Experimental Nanoscience, Taylor & Francis, 2008, 3 (1), pp.17-40. ⟨10.1080/17458080801993422⟩. ⟨hal-00518203⟩
  • Mathieu Mével, Jean-Jacques Yaouanc, Pascal Laurent, Claude Clément, Dominique Cartier, et al.. Cationic Lipids Based on Phosphonate and Phosphoramidate Chemistry: Synthesis and Application to Gene Therapy. Phosphorus, Sulfur, and Silicon and the Related Elements, Taylor & Francis, 2008, 183 (2-3), pp.460 - 468. ⟨10.1080/10426500701761300⟩. ⟨hal-01580434⟩
  • Kadija Kaddur, Anthony Delalande, François Tranquart, Patrick Midoux, Chantal Pichon, et al.. Extraction of green fluorescent proteins with sonoporation. Journal of the Acoustical Society of America, Acoustical Society of America, 2008, 123 (5), pp.3218-3218. ⟨10.1121/1.2933412⟩. ⟨hal-02128161⟩
  • N. Bonnet, C. L. Benhamou, L. Malaval, C. Goncalves, L. Vico, et al.. Low dose beta-blocker prevents ovariectomy-induced bone loss in rats without affecting heart functions.. Journal of Cellular Physiology, Wiley, 2008, 217 (3), pp.819-827. ⟨10.1002/jcp.21564⟩. ⟨hal-00407988⟩
  • Gilles Breuzard, Magdalena Tertil, Cristine Gonçalves, Hervé Cheradame, Philippe Géguan, et al.. Nuclear delivery of NFkappaB-assisted DNA/polymer complexes: plasmid DNA quantitation by confocal laser scanning microscopy and evidence of nuclear polyplexes by FRET imaging.. Nucleic Acids Research, Oxford University Press, 2008, 36 (12), pp.e71. ⟨10.1093/nar/gkn287⟩. ⟨hal-00408004⟩
  • M. Mevel, Gilles Breuzard, J.-J. Yaouanc, J.-C. Clement, P. Lehn, et al.. Synthesis and transfection activity of new cationic phosphoramidate lipids: High efficiency of an imidazolium derivative. ChemBioChem, Wiley-VCH Verlag, 2008, 9 (9), pp.1462-1471. ⟨10.1002/cbic.200700727⟩. ⟨hal-00518184⟩
  • M. Mevel, C. Neveu, Cristine Goncalves, J.-J. Yaouanc, Chantal Pichon, et al.. Novel neutral imidazole-lipophosphoramides for transfection assays. Chemical Communications, Royal Society of Chemistry, 2008, pp.3124-3126. ⟨10.1039/b805226c⟩. ⟨hal-00518192⟩
  • Gilles Breuzard, M. Tertil, Chantal Pichon, Patrick Midoux. Intracellular trafficking and nuclear import of polyplexes by FRET coupled with cellular imaging. Human Gene Therapy, Mary Ann Liebert, 2007, 18, pp.1048. ⟨hal-00275215⟩
  • K. Kaddur, P. Palanchon, F. Tranquart, C. Pichon, A. Bouakaz. Sonopermeabilization: therapeutic alternative with ultrasound and microbubbles. Journal de Radiologie, Elsevier Masson, 2007, 88 (11 part 2), pp.1777-1786. ⟨hal-00282410⟩
  • Mickael Mockey, E. Bourseau, V. Chandrashekhar, A. Chaudhuri, S. Lafosse, et al.. mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes. Cancer Gene Therapy, Nature Publishing Group, 2007, 14, pp.802-814. ⟨10.1038/sj.cgt.7701072⟩. ⟨hal-00159641⟩
  • M. Mockey, C. Goncalves, F.P. Dupuy, F.M. Lemoine, C. Pichon, et al.. mRNA transfection of dendritic cells: synergistic effect of ARCA mRNA capping with Poly(A) chains in cis and in trans for a high protein expression level. Biochemical and Biophysical Research Communications, Elsevier, 2006, 340, pp.1062-1068. ⟨10.1016/j.bbrc.2005.12.105⟩. ⟨hal-00088921⟩
  • Eric Mennesson, Patrick Erbacher, Mateusz Kuzak, Claudine Kieda, Patrick Midoux, et al.. DNA/cationic polymer complex attachment on a human vascular endothelial cell monolayer exposed to a steady laminar flow. Journal of Controlled Release, Elsevier, 2006, 114 (3), pp.389-397. ⟨10.1016/j.jconrel.2006.06.006⟩. ⟨hal-00112894⟩
  • E. Mennesson, P. Erbacher, V. Piller, C. Kieda, P. Midoux, et al.. Transfection efficiency and uptake process of polyplexes in human lung endothetial cells: a comparative study in non-polarized and polarized cells. The Journal of Gene Medicine, Wiley, 2005, 7, pp.729-738. ⟨hal-00088642⟩
  • Ibrahim Elmadbouh, Patrick Rossignol, Olivier Meilhac, Roger Vranckx, Chantal Pichon, et al.. Optimization of in vitro vascular cell transfection with non-viral vectors for in vivo applications. The Journal of Gene Medicine, Wiley, 2004, 6 (10), pp.1112-1124. ⟨hal-00014241⟩
  • R.S. Singh, C. GonÇalves, P. Sandrin, C. Pichon, P. Midoux, et al.. On the gene delivery efficacies of pH-sensitive cationic lipids via endosomal protonation: a chemical biology investigation. Chemistry & biology, 2004, 11, pp.713-723. ⟨hal-00088426⟩
  • T. Montier, P. DelÉpine, C. Pichon, C. Férec, D.J. Porteous, et al.. Non-viral vectors in cystic fibrosis gene therapy: progress and challenges. Trends in biotechnology., 2004, 22, pp.586-592. ⟨hal-00088424⟩
  • C. Goncalves, E. Mennesson, R. Fuchs, Gorvel J.P., C. Pichon. Macropinocytosis of polyplexes and recycling of plasmid via the clathrin-dependant pathway impair the transfection efficiency into human hepatocarcinoma cells. Molecular Therapy, Nature Publishing Group, 2004, 10, pp.373-385. ⟨hal-00113047⟩
  • Christine Gonçalves, Chantal Pichon, Brigitte Guérin, Patrick Midoux. Intracellular processing and stability of DNA complexed with histidylated polylysine conjugates. The Journal of Gene Medicine, Wiley, 2002, 4 (3), pp.271-281. ⟨10.1002/jgm.277⟩. ⟨hal-02135970⟩
  • Chantal Pichon, Eric Lecam, Brigitte Guérin, Dominique Coulaud, Etienne Delain, et al.. Poly[Lys-(AEDTP)]: a cationic polymer that allows dissociation of pDNA/cationic polymer complexes in a reductive medium and enhances polyfection.. Bioconjugate Chemistry, American Chemical Society, 2002, 13 (1), pp.76-82. ⟨hal-02135235⟩
  • Chantal Pichon, Brigitte Guérin, Matthieu Refregiers, Christine Gonçalves, Paul Vigny, et al.. Zinc improves gene transfer mediated by DNA/cationic polymer complexes. The Journal of Gene Medicine, Wiley, 2002, 4 (5), pp.548 - 559. ⟨10.1002/jgm.303⟩. ⟨hal-01596013⟩
  • V Kumar, Chantal Pichon, M. Refregiers, B Guerin, P. Midoux, et al.. Single histidine residue in head-group region is sufficient to impart remarkable gene transfection properties to cationic lipids: evidence for histidine-mediated membrane fusion at acidic pH. Gene Therapy, Nature Publishing Group, 2002, 10 (15), pp.1206 - 1215. ⟨10.1038/sj.gt.3301979⟩. ⟨hal-01596052⟩
  • Chantal Pichon, C Gonçalves, P. Midoux. Histidine-rich peptides and polymers for nucleic acids delivery.. Advanced Drug Delivery Reviews, Elsevier, 2001, 53 (1), pp.75-94. ⟨hal-02135973⟩
  • Fabien Dorange, Slimane El Mehdaoui, Chantal Pichon, Pierre Coursaget, Jean-François Vautherot. Marek’s disease virus (MDV) homologues of herpes simplex virus type 1 UL49 (VP22) and UL48 (VP16) genes: high-level expression and characterization of MDV-1 VP22 and VP16. Journal of General Virology, Microbiology Society, 2000, 81 (9), pp.2219-2230. ⟨10.1099/0022-1317-81-9-2219⟩. ⟨hal-02135997⟩
  • Isabelle Fajac, J.C Allo, Evelyne Souil, Marc Merten, Chantal Pichon, et al.. Histidylated polylysine as a synthetic vector for gene transfer into immortalized cystic fibrosis airway surface and airway gland serous cells. The Journal of Gene Medicine, Wiley, 2000, 2 (5), pp.368-378. 3.0.CO;2-F">⟨10.1002/1521-2254(200009/10)2:5<368::AID-JGM118>3.0.CO;2-F⟩. ⟨hal-02135988⟩
  • Chantal Pichon, Mahajoub Bello Roufaï, Michel Monsigny, Patrick Midoux. Histidylated oligolysines increase the transmembrane passage and the biological activity of antisense oligonucleotides. Nucleic Acids Research, Oxford University Press, 2000, 28 (2), pp.504-512. ⟨10.1093/nar/28.2.504⟩. ⟨hal-02135979⟩
  • Chantal Pichon, Michel Monsigny, Annie-Claude Roche. Intracellular Localization of Oligonucleotides: Influence of Fixative Protocols. Antisense and Nucleic Acid Drug Development, Mary Ann Liebert, 1999, 9 (1), pp.89-93. ⟨10.1089/oli.1.1999.9.89⟩. ⟨hal-02135999⟩
  • M Monsigny, C. Quétard, S. Bourgerie, D. Delay, Chantal Pichon, et al.. Glycotargeting: the preparation of glyco-amino acids and derivatives from unprotected reducing sugars.. Biochimie, Elsevier, 1998, 80 (2), pp.99-108. ⟨hal-02136005⟩
  • C Pichon, K Arar, A. Stewart, M Dodon, L Gazzolo, et al.. Intracellular routing and inhibitory activity of oligonucleopeptides containing a KDEL motif.. Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 1997, 51 (3), pp.431-8. ⟨hal-02124430⟩
  • Chantal Pichon, Isabelle Freulon, Patrick Midoux, Roger Mayer, Michel Monsigny, et al.. Cytosolic and Nuclear Delivery of Oligonucleotides Mediated by an Amphiphilic Anionic Peptide. Antisense and Nucleic Acid Drug Development, Mary Ann Liebert, 1997, 7 (4), pp.335-343. ⟨10.1089/oli.1.1997.7.335⟩. ⟨hal-02136009⟩
  • A. Stewart, Chantal Pichon, L Meunier, P Midoux, M. Monsigny, et al.. Enhanced biological activity of antisense oligonucleotides complexed with glycosylated poly-L-lysine.. Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 1996, 50 (6), pp.1487-94. ⟨hal-02136015⟩

Communication dans un congrès

  • Vinodini Vijayarangan, Anthony Delalande, Sébastien Dozias, Jean-Michel Pouvesle, Chantal Pichon, et al.. Helium Plasma Jet for Cell Membrane Permeabilization and Drug Delivery Application. SFNano 2018, SFN, Dec 2018, Montpellier, France. ⟨hal-01946070⟩
  • Vinodini Vijayarangan, Anthony Delalande, Sébastien Dozias, Jean-Michel Pouvesle, Chantal Pichon, et al.. Helium Plasma Jet: A tool for Cell Membrane Permeabilization. Journées du GDR HAPPYBio, GDR HAPPYBio, Nov 2018, Paris, France. ⟨hal-01946046⟩
  • Vinodini Vijayarangan, Anthony Delalande, Sébastien Dozias, Jean-Michel Pouvesle, Chantal Pichon, et al.. Cold Atmospheric Plasma Parameters Investigation for Drug Delivery Applications. ICPM7, ISPM, Jun 2018, Philadelphia, United States. ⟨hal-01942869⟩
  • Vinodini Vijayarangan, Anthony Delalande, Sébastien Dozias, Jean-Michel Pouvesle, Chantal Pichon, et al.. Investigation of cell membrane permeabilization induced by plasma treatment for drug delivery applications. Journées du GDR ABioPlas, GDR ABioPlas, Oct 2017, Paris, France. ⟨hal-01945957⟩
  • Vinodini Vijayarangan, Anthony Delalande, Claire Douat, Sébastien Dozias, Jean-Michel Pouvesle, et al.. INVESTIGATION OF CELL MEMBRANE PERMEABILIZATION INDUCED BY PLASMA TREATMENT FOR DRUG DELIVERY APPLICATIONS. IWPCT4, Mar 2017, Paris, France. ⟨hal-01944604⟩
  • Vinodini Vijayarangan, Anthony Delalande, Claire Douat, Sébastien Dozias, Jean-Michel Pouvesle, et al.. STUDY OF PLASMA COMPONENT EFFECT ON CELL MEMBRANE PERMEABILIZATION FOR DRUG DELIVERY APPLICATIONS. 23rd International Symposium on Plasma Chemistry, Jul 2017, Montreal, Canada. ⟨hal-01610921⟩
  • Claire Douat, Giovanni Busco, Vini Vijayarangan, Sebastien Dozias, Sylvain Iséni, et al.. Challenges in the transition from in vitro to in vivo experiments: source effects and biological aspects. IWPCT3, Apr 2016, Washington, United States. ⟨hal-01340223⟩
  • Eric Robert, Xavier Damany, Sylvain Iséni, Marc Vandamme, Sébastien Dozias, et al.. Bio environmental applications of plasmas . Frontiers in Plasma Science 2, Feb 2016, Greifswald, Germany. ⟨hal-01344069⟩
  • Eric Robert, Sylvain Iséni, Claire Douat, Vinodini Vijayarangan, Anthony Delalande, et al.. Non thermal plasma jets and plasma jet electric fields for biomedical and agricultural applications. 13th International Bioelctrics Symposium, Sep 2016, Rostock, Germany. ⟨hal-01944556⟩
  • Claire Douat, Vinodini Vijayarangan, Thibault Darny, Sylvain Iséni, Xavier Damany, et al.. Perméabilisation de la membrane plasmique par un jet de plasma. Journées du GDR ABioPlas, GDR ABioPlas, Nov 2016, Albi, France. ⟨hal-01945754⟩
  • Claire Douat, Thibault Darny, Sylvain Iseni, Xavier Damany, Sebastien Dozias, et al.. Impact of electric field from a plasma jet on biological targets. 69th Gaseous Electronic Conference, Oct 2016, Bochum, Germany. ⟨hal-01385203⟩
  • Simona Manta, Anthony Delalande, Gilles Renault, Michel Francis Bureau, Matthias Lebertre, et al.. Positively charged microbubbles to target nucleic acid delivery with ultrasound. Journées RITS 2015, Mar 2015, Dourdan, France. ⟨inserm-01154976⟩
  • Spiros Kotopoulis, Anthony Delalande, Chantal Pichon, Michiel Postema. Real-time sonoporation through HeLa cells. 19th International Symposium on Nonlinear Acoustics, Sep 2012, Tokyo, Japan. pp.271-274. ⟨hal-02128171⟩

Poster

  • Marlène Dezest, Vinodini Vijayarangan, Anthony Delalande, Chantal Pichon, Sylvain Iséni, et al.. Cell Response to He, He-O2 Plasma and Plasma Electric Field Alone Treatments. ICPM6, Sep 2016, Bratislava, Slovakia. ⟨hal-01948526⟩

Chapitre d'ouvrage

  • Magdalena Wytrwal, Chantal Pichon. Polyallylamine Derivatives: Novel NonToxic Transfection Agents. Methods in molecular biology, pp.159-174, 2016, ⟨10.1007/978-1-4939-3718-9_10⟩. ⟨hal-02071774⟩
  • Chantal Pichon, Patrick Midoux. Mannosylated and Histidylated LPR Technology for Vaccination with Tumor Antigen mRNA. Synthetic Messenger RNA and Cell Metabolism Modulation, pp.247-274, 2013, ⟨10.1007/978-1-62703-260-5_16⟩. ⟨hal-02070913⟩
  • P. Midoux, E. Lecam, D. Coulaud, E. Delain, C. Pichon. Histidine containing peptides and polypeptides as nucleic acid vectors. Luo D., Saltzman W.M. Synthetic DNA Delivery Systems, Kluwer Academic/Plenum Publishers, New-York, pp.23-44, 2003. ⟨hal-00115810⟩
  • P. Midoux, C. Pichon. Peptide-based gene delivery systems. Mahato R.I., Kim S.W. Pharmaceutical perspectives of nucleic acid-based, Taylor & Francis, London and New York, pp.334-366, 2002. ⟨hal-00115804⟩
  • P. Midoux, C. Pichon. Histidylated polycationic molecules for nucleic acids transfer. Pandalai S.G. Recent research developments in bioconjugate chemistry, Transworld Research Network, Trivandrum, pp.95-111, 2002. ⟨hal-00115805⟩
  • M. Monsigny, C. Quétard, E. Duverger, C. Pichon, V. Altemayer, et al.. Glycoconjugates as vectors for gene and oligonucleotide delivery. Aubery M. Glycans in cellular interaction and recognition: therapeutic, Harwood Academic Publishers, Amsterdam, pp.193-215, 2002. ⟨hal-00115807⟩

Brevet

  • Jean-Marc Malinge, Patrick Midoux, Thomas Thibault, Chantal Pichon. In vitro production of DNA minicircles less than 250 base pairs. France, Patent n° : EP2735614A1. 2014. ⟨hal-02134791⟩