REVERCHON-ASSADI Flora

email : flora.reverchon@cnrs-orleans.fr

Téléphone : 02.38.25.55.75

Bureau A117

Postdoctorante chercheure au sein du groupe thématique “Cibles pharmacologiques et biomarqueurs”

 



2 documents

Article dans une revue

  • Chayma El Khamlichi, Flora Reverchon-Assadi, Nadège Hervouet-Coste, Lauren Blot, Eric Reiter, et al.. Bioluminescence Resonance Energy Transfer as a Method to Study Protein-Protein Interactions: Application to G Protein Coupled Receptor Biology. Molecules, MDPI, 2019, 24 (3), pp.537. ⟨10.3390/molecules24030537⟩. ⟨hal-02067271⟩
  • Flora Reverchon, Stéphane Mortaud, Maëliss Sivoyon, Isabelle Maillet, Anthony Laugeray, et al.. IL-33 receptor ST2 regulates the cognitive impairments associated with experimental cerebral malaria. PLoS Pathogens, Public Library of Science, 2017, 13 (4), ⟨10.1371/journal.ppat.1006322⟩. ⟨hal-01656488⟩

MORISSET-LOPEZ Séverine

email : severine.morisset-lopez@cnrs-orleans.fr

Téléphone : 02.38.25.78.58

Bureau A116

Chargée de recherche et co-responsable du Groupe “Cibles pharmacologiques et biomarqueurs”

Profil sur ORCID

Profil sur ResearchID



40 documents

Article dans une revue

  • Chayma El Khamlichi, Flora Reverchon-Assadi, Nadège Hervouet-Coste, Lauren Blot, Eric Reiter, et al.. Bioluminescence Resonance Energy Transfer as a Method to Study Protein-Protein Interactions: Application to G Protein Coupled Receptor Biology. Molecules, MDPI, 2019, 24 (3), pp.537. ⟨10.3390/molecules24030537⟩. ⟨hal-02067271⟩
  • Viorel Simion, Wissem Deraredj Nadim, Hélène Bénédetti, Chantal Pichon, Séverine Morisset-Lopez, et al.. Pharmacomodulation of microRNA Expression in Neurocognitive Diseases: Obstacles and Future Opportunities. Current Neuropharmacology, Bentham Science Publishers, 2017, 15 (2), pp.276 - 290. ⟨10.2174/1570159X14666160630210422⟩. ⟨hal-01618771⟩
  • Wissem Deraredj Nadim, Simion Viorel, Hélène Bénédetti, Chantal Pichon, Patrick Baril, et al.. MicroRNAs in Neurocognitive Dysfunctions: New Molecular Targets for Pharmacological Treatments?. Current Neuropharmacology, Bentham Science Publishers, 2017, 15 (2), pp.260 - 275. ⟨10.2174/1570159X14666160709001441⟩. ⟨hal-01618199⟩
  • Yacine Chebani, Candice Marion, Philippe Zizzari, Khadidja Chettab, Marie Pastor, et al.. Enhanced responsiveness of Ghsr Q343X rats to ghrelin results in enhanced adiposity without increased appetite. Science Signaling, American Association for the Advancement of Science, 2016, 9 (424), pp.ra39. ⟨10.1126/scisignal.aae0374⟩. ⟨inserm-01463897⟩
  • Wissem Deraredj Nadim, Séverine Chaumont-Dubel, Fahima Madouri, Laetitia Cobret, Marie-Ludivine de Tauzia, et al.. Physical interaction between neurofibromin and serotonin 5-HT 6 receptor promotes receptor constitutive activity. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2016, 113 (43), pp.12310 - 12315. ⟨10.1073/pnas.1600914113⟩. ⟨hal-01407899⟩
  • Emmanuel Deau, Elodie Robin, Raluca Voinea, Nathalie Percina, Grzegorz Satała, et al.. Rational Design, Pharmacomodulation, and Synthesis of Dual 5-Hydroxytryptamine 7 (5-HT 7 )/5-Hydroxytryptamine 2A (5-HT 2A ) Receptor Antagonists and Evaluation by [ 18 F]-PET Imaging in a Primate Brain. Journal of Medicinal Chemistry, American Chemical Society, 2015, 58 (20), pp.8066-8096. ⟨10.1021/acs.jmedchem.5b00874⟩. ⟨hal-02068052⟩
  • L Cobret, M L de Tauzia, J Ferent, E Traiffort, I Hénaoui, et al.. Targeting the cis-dimerization of LINGO-1 with low MW compounds affects its downstream signalling. British Journal of Clinical Pharmacology, Wiley, 2015, 172 (3), pp.841-856. ⟨10.1111/bph.12945⟩. ⟨hal-01170735⟩
  • Fanny Duhr, Paul Déléris, Fabrice Raynaud, Martial Séveno, Séverine Morisset-Lopez, et al.. Cdk5 induces constitutive activation of 5-HT6 receptors to promote neurite growth. Nature Chemical Biology, Nature Publishing Group, 2014, 10 (7), pp.590-597. ⟨10.1038/nchembio.1547⟩. ⟨hal-01178901⟩
  • Fabienne Godin, Sandrine Villette, Béatrice Vallée, Michel Doudeau, Séverine Morisset-Lopez, et al.. A fraction of neurofibromin interacts with PML bodies in the nucleus of the CCF astrocytoma cell line.. Biochemical and Biophysical Research Communications, Elsevier, 2012, 418 (4), pp.689-94. ⟨10.1016/j.bbrc.2012.01.079⟩. ⟨hal-00721861⟩
  • M. Picard, S. Morisset, J.F. Cloix, J.C. Bizot, M. Guerin, et al.. Pharmacological, neurochemical, and behavioral profile of JB-788, a new 5-HT1A agonist. Neuroscience, Elsevier - International Brain Research Organization, 2010, 169 (3), pp.1337-1346. ⟨10.1016/j.neuroscience.2010.05.040⟩. ⟨hal-02071835⟩
  • Mouhammad Motawaj, Aude Burban, Elisabeth Davenas, Florence Gbahou, Raphaël Faucard, et al.. Le système histaminergique : une cible pour de nouveaux traitements des deficits cognitifs. Thérapie, EDP Sciences, 2010, 65 (5), pp.415-422. ⟨10.2515/therapie/2010058⟩. ⟨hal-02071208⟩
  • F. Gbahou, E. Davenas, S. Morisset, J.- Arrang. Effects of Betahistine at Histamine H3 Receptors: Mixed Inverse Agonism/Agonism In Vitro and Partial Inverse Agonism In Vivo. Journal of Pharmacology and Experimental Therapeutics, American Society for Pharmacology and Experimental Therapeutics, 2010, 334 (3), pp.945-954. ⟨10.1124/jpet.110.168633⟩. ⟨hal-02071192⟩
  • W. Beghdadi, A. Porcherie, Schneider B.S., S. Morisset, D. Dubayle, et al.. Histamine H3 receptor-mediated signaling protects mice from cerebral malaria.. PLoS ONE, Public Library of Science, 2009, 4, pp.e6004. ⟨hal-00397938⟩
  • Jacques Pantel, Marie Legendre, Sylvie Nivot, Séverine Morisset, Marie Vie-Luton, et al.. Recessive Isolated Growth Hormone Deficiency and Mutations in the Ghrelin Receptor. Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2009, 94 (11), pp.4334-4341. ⟨10.1210/jc.2009-1327⟩. ⟨hal-02081574⟩
  • E. Davenas, A. Rouleau, S. Morisset, J. Arrang. Autoregulation of McA-RH7777 Hepatoma Cell Proliferation by Histamine H3 Receptors. Journal of Pharmacology and Experimental Therapeutics, American Society for Pharmacology and Experimental Therapeutics, 2008, 326 (2), pp.406-413. ⟨10.1124/jpet.107.135368⟩. ⟨hal-02081595⟩
  • Marie Humbert-Claude, Séverine Morisset, Florence Gbahou, Jean-Michel Arrang. Histamine H3 and dopamine D2 receptor-mediated [35S]GTPγ[S] binding in rat striatum: Evidence for additive effects but lack of interactions. Biochemical Pharmacology, Elsevier, 2007, 73 (8), pp.1172-1181. ⟨10.1016/j.bcp.2007.01.006⟩. ⟨hal-02081605⟩
  • Jean-Michel Arrang, Séverine Morisset, Florence Gbahou. Constitutive activity of the histamine H3 receptor. Trends in Pharmacological Sciences, Elsevier, 2007, 28 (7), pp.350-357. ⟨10.1016/j.tips.2007.05.002⟩. ⟨hal-02081603⟩
  • M. Humbert-Claude, S Morisset-Lopez, F. Gbahou, M. Arrang. Potential molecular interactions between the histamine H3 receptor and the dopamine D2 receptor in the rat striatum. European Neuropsychopharmacology, Elsevier, 2006, 16, pp.S16-S17. ⟨10.1016/s0924-977x(06)80021-0⟩. ⟨hal-02082149⟩
  • J. Pantel, Marie Legendre, Sylvie Cabrol, Latifa Hilal, Yassir Hajaji, et al.. Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature. Journal of Clinical Investigation, American Society for Clinical Investigation, 2006, 116 (3), pp.760-768. ⟨10.1172/JCI25303⟩. ⟨hal-02082146⟩
  • S Morisset-Lopez, C. Chabret, J.M. Arrang. P.1.31 Constitutive dimerization of the histamineH3 receptor in living cells. European Neuropsychopharmacology, Elsevier, 2005, 15, pp.S25-S26. ⟨10.1016/s0924-977x(05)80136-1⟩. ⟨hal-02082151⟩
  • F. Gbahou, A. Rouleau, S Morisset-Lopez, X. Ligneau, J. Tardivel-Lacombe, et al.. P.1.03 Constitutive activity of the recombinant and native histamine H3 receptor: effects of inverse agonists and protean agonists. European Neuropsychopharmacology, Elsevier, 2004, 14, pp.S4-S5. ⟨10.1016/s0924-977x(04)90004-1⟩. ⟨hal-02081569⟩
  • Brigitte Ilien, Christelle Franchet, Philippe Bernard, Séverine Morisset, Claire Odile Weill, et al.. Fluorescence resonance energy transfer to probe human M1 muscarinic receptor structure and drug binding properties.. Journal of neurochemistry, 2003, 85 (3), pp.768-78. ⟨hal-02081577⟩
  • J.M. Arrang, S. Morisset, A. Rouleau, F. Gbahou, X. Ligneau, et al.. Constitutive activity of the recombinant and native histamine H3 receptor. International Congress Series, Elsevier, 2003, 1249, pp.139-151. ⟨10.1016/S0531-5131(03)00617-4⟩. ⟨hal-02081573⟩
  • J.M. Arrang, S Morisset-Lopez, A. Rouleau, F. Gbahou, X. Ligneau, et al.. S.16.04 Histamine H3-receptor ligands: Effects of inverse agonists and protean ligands. European Neuropsychopharmacology, Elsevier, 2003, 13, pp.S141. ⟨10.1016/s0924-977x(03)91663-4⟩. ⟨hal-02081585⟩
  • F. Gbahou, A. Rouleau, S Morisset-Lopez, R. Parmentier, S. Crochet, et al.. Protean agonism at histamine H3 receptors in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2003, 100 (19), pp.11086-11091. ⟨10.1073/pnas.1932276100⟩. ⟨hal-02081588⟩
  • J. C. Schwartz, S Morisset-Lopez, A. Rouleau, X. Ligneau, F. Gbahou, et al.. Therapeutic implications of constitutive activity of receptors: the example of the histamine H3 receptor.. Journal of Neural Transmission Supplementum, Wien; New York; Springer; 1999, 2003, pp.1-16. ⟨hal-02081590⟩
  • A. Rouleau, X Ligneau, J. Tardivel-Lacombe, S Morisset-Lopez, F Gbahou, et al.. Histamine H 3 -receptor-mediated [ 35 S]GTPγ[S] binding: evidence for constitutive activity of the recombinant and native rat and human H 3 receptors. British Journal of Pharmacology, Wiley, 2002, 135 (2), pp.383-392. ⟨10.1038/sj.bjp.0704490⟩. ⟨hal-02082155⟩
  • S Morisset-Lopez, P Pilon, J. Tardivel-Lacombe, W Weinstein, W. Rostene, et al.. Acute and chronic effects of methamphetamine on tele-methylhistamine levels in mouse brain: selective involvement of the D(2) and not D(3) receptor.. Journal of Pharmacology and Experimental Therapeutics, American Society for Pharmacology and Experimental Therapeutics, 2002, 300 (2), pp.621-8. ⟨hal-02082246⟩
  • C. Chotard, T. Ouimet, S. Morisset, U. Sahm, C. Schwartz, et al.. Effects of histamine H 3 receptor agonist and antagonist on histamine co-transmitter expression in rat brain. Journal of Neural Transmission, Springer Verlag, 2002, 109 (3), pp.293-306. ⟨10.1007/s007020200024⟩. ⟨hal-02081594⟩
  • Jean-Charles Schwartz, Séverine Morisset, Agnès Rouleau, Joël Tardivel-Lacombe, Florence Gbahou, et al.. Application of genomics to drug design: the example of the histamine H3 receptor. European Neuropsychopharmacology, Elsevier, 2001, 11 (6), pp.441-448. ⟨10.1016/s0924-977x(01)00121-3⟩. ⟨hal-02129745⟩
  • Séverine Morisset, Astrid Sasse, Florence Gbahou, Anne Héron, Xavier Ligneau, et al.. The Rat H3 Receptor: Gene Organization and Multiple Isoforms. Biochemical and Biophysical Research Communications, Elsevier, 2001, 280 (1), pp.75-80. ⟨10.1006/bbrc.2000.4073⟩. ⟨hal-02082164⟩
  • Joël Tardivel-Lacombe, Séverine Morisset, Florence Gbahou, Jean-Charles Schwartz, Jean-Michel Arrang. Chromosomal mapping and organization of the human histamine H3 receptor gene. NeuroReport, Lippincott, Williams & Wilkins, 2001, 12 (2), pp.321-324. ⟨10.1097/00001756-200102120-00028⟩. ⟨hal-02082162⟩
  • C Ito, S Morisset-Lopez, J-P Olié, H Lôo, M-F Poirier, et al.. Histamine H2 receptor gene variants: lack of association with schizophrenia. Molecular Psychiatry, Nature Publishing Group, 2000, 5 (2), pp.159-164. ⟨10.1038/sj.mp.4000664⟩. ⟨hal-02082207⟩
  • X. Ligneau, S Morisset-Lopez, J. Tardivel-Lacombe, F Gbahou, C Ganellin, et al.. Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain.. British Journal of Pharmacology, Wiley, 2000, 131 (7), pp.1247-50. ⟨10.1038/sj.bjp.0703712⟩. ⟨hal-02081534⟩
  • S. Morisset, E. Traiffort, J. M. Arrang, J. C. Schwartz. Changes in histamine H3 receptor responsiveness in mouse brain.. Journal of Neurochemistry, Wiley, 2000, 74 (1), pp.339-46. ⟨hal-00347608⟩
  • S. Morisset, A. Rouleau, X Ligneau, F Gbahou, J. Tardivel-Lacombe, et al.. High constitutive activity of native H3 receptors regulates histamine neurons in brain.. Nature, Nature Publishing Group, 2000, 408 (6814), pp.860-4. ⟨10.1038/35048583⟩. ⟨hal-02081523⟩
  • S Morisset-Lopez, Agnés Rouleau, Anne Héron, Joël Tardivel-Lacombe, Séverine Morisset, et al.. Cloning and cerebral expression of the guinea pig histamine H3 receptor. NeuroReport, Lippincott, Williams & Wilkins, 2000, 11 (4), pp.755-759. ⟨10.1097/00001756-200003200-00020⟩. ⟨hal-02082171⟩
  • S. Morisset, U. G. Sahm, E. Traiffort, J. Tardivel-Lacombe, J. M. Arrang, et al.. Atypical neuroleptics enhance histamine turnover in brain via 5-Hydroxytryptamine2A receptor blockade.. Journal of Pharmacology and Experimental Therapeutics, American Society for Pharmacology and Experimental Therapeutics, 1999, 288 (2), pp.590-6. ⟨hal-00347619⟩
  • Séverine Morisset, Elisabeth Traiffort, Jean-Charles Schwartz. Inhibition of histamine versus acetylcholine metabolism as a mechanism of tacrine activity. European Journal of Pharmacology, Elsevier, 1996, 315 (1), pp.R1-R2. ⟨10.1016/s0014-2999(96)00738-8⟩. ⟨hal-02081407⟩

Brevet

  • Séverine Morisset-Lopez, Hélène Bénédetti. TOOLS FOR THE IDENTIFICATION OF LINGO-1, LINGO-2, LINGO-3 AND LINGO-4, LIGANDS, AND USES THEREOF. France, Patent n° : WO2011121257. 2011. ⟨hal-02130935⟩

KIEDA Claudine

email : claudine.kieda@cnrs-orleans.fr

Téléphone : 02.38.25.55.61

Bureau A214

Directrice de recherche émérite au sein du Groupe thématique “Biologie de la peau” et du groupe thématique “Cibles pharmacologiques et biomarqueurs”

 



documents

HERVOUET-COSTE Nadège

email : nadege.hervouet@cnrs-orleans.fr

Téléphone : 02.38.25.56.10

Bureau A117

Assistante ingénieure en biologie, sciences de la vie et de la terre au sein du groupe thématique “Cibles pharmacologiques et biomarqueurs”

 



13 documents

Article dans une revue

  • Chayma El Khamlichi, Flora Reverchon-Assadi, Nadège Hervouet-Coste, Lauren Blot, Eric Reiter, et al.. Bioluminescence Resonance Energy Transfer as a Method to Study Protein-Protein Interactions: Application to G Protein Coupled Receptor Biology. Molecules, MDPI, 2019, 24 (3), pp.537. ⟨10.3390/molecules24030537⟩. ⟨hal-02067271⟩
  • Christine Mosrin-Huaman, Nadège Hervouet-Coste, A. Rachid Rahmouni. Co-transcriptional degradation by the 5′-3′ exonuclease Rat1p mediates quality control of HXK1 mRNP biogenesis in S. cerevisiae. RNA Biology, Taylor & Francis, 2016, 13 (6), pp.582 - 592. ⟨10.1080/15476286.2016.1181255⟩. ⟨hal-01407513⟩
  • Christine Mosrin-Huaman, Nadege Hervouet-Coste, Aurélia Le Dantec, Igor Stuparevic, A. Rachid Rahmouni. Bacterial Rho helicase: a new tool to dissect mRNP biogenesis and quality control in yeast. Trends in cell and molecular biology, Research Trends, 2014, 9, pp.79 - 93. ⟨hal-01179495⟩
  • Igor Stuparevic, Christine Mosrin-Huaman, Nadège Hervouet-Coste, Mateja Remenaric, A. Rachid Rahmouni. Co-transcriptional recruitment of the RNA exosome cofactors Rrp47p, Mpp6p and two distinct TRAMP complexes assists the exonuclease Rrp6p in the targeting and degradation of an aberrant mRNP in yeast. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2013, ⟨10.1074/jbc.M113.491290⟩. ⟨hal-00874892⟩
  • Romy Honorine, Christine Mosrin-Huaman, Nadege Hervouet-Coste, Domenico Libri, Rachid A. Rahmouni. Nuclear mRNA quality control in yeast is mediated by Nrd1 co-transcriptional recruitment, as revealed by the targeting of Rho-induced aberrant transcripts. Nucleic Acids Research, Oxford University Press, 2011, 39 (7), pp.2809-2820. ⟨10.1093/nar/gkq1192⟩. ⟨hal-00602376⟩
  • Yumiko Mishima, Franck Coste, Vanessa Bobezeau, Nadège Hervouet, Christine Kellenberger, et al.. Expression, purification, crystallization and preliminary X-ray analysis of the N-terminal domain of GNBP3 from Drosophila melanogaster. Acta crystallographica. Section F, Structural biology communications, John Wiley & Sons Ltd,, 2009, 65 (Part 9), pp.870-873. ⟨10.1107/S1744309109014997⟩. ⟨hal-00525123⟩
  • Franck Coste, Matthias Ober, Yann-Vaï Le Bihan, Maria Angeles Izquierdo, Nadège Hervouet, et al.. Bacterial base excision repair enzyme Fpg recognizes bulky N7-substituted-FapydG lesion via unproductive binding mode.. Chemistry & Biology / Chemistry and Biology; CHEMISTRY & BIOLOGY, 2008, 15 (7), pp.706-17. ⟨10.1016/j.chembiol.2008.05.014⟩. ⟨hal-00408047⟩
  • Audrey Oudin, Samira Mahroug, Vincent Courdavault, Nadège Hervouet, Charles Zelwer, et al.. Spatial distribution and hormonal regulation of gene products from methyl erythritol phosphate and monoterpene-secoiridoid pathways in Catharanthus roseus. Plant Molecular Biology, Springer Verlag (Germany), 2007, 65 (1-2), pp.13-30. ⟨10.1007/s11103-007-9190-7⟩. ⟨hal-00166605⟩
  • S. Quevillon-Cheruel, N. Leulliot, M. Graille, N. Hervouet, F. Coste, et al.. Crystal structure of yeast YHR049W/FSH1, a member of the serine hydrolase family. Protein science : a publication of the Protein Society., 2005, 14, pp.1350-1356. ⟨hal-00088667⟩
  • Charles Ramstein, Nadège Hervouet, Franck Coste, Charles Zelwer, Jacques Oberto, et al.. Evidence of a thermal unfolding dimeric intermediate for the Escherichia coli histone-like HU proteins: thermodynamics and structure.. Journal of Molecular Biology, Elsevier, 2003, 331 (1), pp.101-21. ⟨hal-02127656⟩
  • Karine Pereira de Jésus, Laurence Serre, Nadège Hervouet, Véronique Bouckson-Castaing, Charles Zelwer, et al.. Crystallization and preliminary X-ray crystallographic studies of a complex between the Lactococcus lactis Fpg DNA-repair enzyme and an abasic site containing DNA. Acta Crystallographica Section D: Biological Crystallography, International Union of Crystallography, 2002, 58 (4), pp.679-682. ⟨10.1107/S0907444902001397⟩. ⟨hal-02141124⟩
  • Bertrand Castaing, Jean-Louis Fourrey, Nadege Hervouet-Coste, Martial Thomas, Serge Boiteux, et al.. AP site structural determinants for Fpg specific recognition. Nucleic Acids Research, Oxford University Press, 1999, 27 (2), pp.608-615. ⟨10.1093/nar/27.2.608⟩. ⟨hal-02141144⟩
  • Franck Coste, N. Hervouet, J. Oberto, C. Zelwer, Bertrand Castaing. Crystallization and preliminary X-ray diffraction analysis of the homodimeric form alpha2 of the HU protein from Escherichia coli.. Acta Crystallographica Section D: Biological Crystallography, International Union of Crystallography, 1999, 55 (Pt 11), pp.1952-4. ⟨hal-02127644⟩