MOSRIN-HUAMAN Christine

email : christine.mosrin@cnrs-orleans.fr

Téléphone : 02.38.25.76.11

Bureau D204

Chargée de recherche au sein du Groupe thématique “Signalisation cellulaire”

 



10 documents

Article dans une revue

  • Kévin Moreau, Aurélia Le Dantec, Christine Mosrin-Huaman, Yves Bigot, Benoit Piegu, et al.. Perturbation of mRNP biogenesis reveals a dynamic landscape of the Rrp6-dependent surveillance machinery trafficking along the yeast genome. RNA Biology, Taylor & Francis, 2019, pp.1-11. ⟨10.1080/15476286.2019.1593745⟩. ⟨hal-02117640⟩
  • Kévin Moreau, Justine Surand, Aurélia Le Dantec, Christine Mosrin-Huaman, Alain Legrand, et al.. Recombinant yeast and human cells as screening tools to search for antibacterial agents targeting the transcription termination factor Rho. Journal of Antibiotics, Nature Publishing Group: Open Access Hybrid Model Option B, 2018, 71 (4), pp.447-455. ⟨hal-01966171⟩
  • Christine Mosrin-Huaman, Nadège Hervouet-Coste, A. Rachid Rahmouni. Co-transcriptional degradation by the 5′-3′ exonuclease Rat1p mediates quality control of HXK1 mRNP biogenesis in S. cerevisiae. RNA Biology, Taylor & Francis, 2016, 13 (6), pp.582 - 592. ⟨10.1080/15476286.2016.1181255⟩. ⟨hal-01407513⟩
  • Rachid A. Rahmouni, Christine Mosrin-Huaman. In Situ Footprinting of E. coli Transcription Elongation Complex with Chloroacetaldehyde. Methods in Molecular Biology, Humana Press/Springer Imprint, 2015, Methods in Molecular Biology, 1276, pp.229-240. ⟨10.1007/978-1-4939-2392-2_13⟩. ⟨hal-01171857⟩
  • Christine Mosrin-Huaman, Nadege Hervouet-Coste, Aurélia Le Dantec, Igor Stuparevic, A. Rachid Rahmouni. Bacterial Rho helicase: a new tool to dissect mRNP biogenesis and quality control in yeast. Trends in cell and molecular biology, Research Trends, 2014, 9, pp.79 - 93. ⟨hal-01179495⟩
  • Igor Stuparevic, Christine Mosrin-Huaman, Nadège Hervouet-Coste, Mateja Remenaric, A. Rachid Rahmouni. Co-transcriptional recruitment of the RNA exosome cofactors Rrp47p, Mpp6p and two distinct TRAMP complexes assists the exonuclease Rrp6p in the targeting and degradation of an aberrant mRNP in yeast. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2013, ⟨10.1074/jbc.M113.491290⟩. ⟨hal-00874892⟩
  • Romy Honorine, Christine Mosrin-Huaman, Nadege Hervouet-Coste, Domenico Libri, Rachid A. Rahmouni. Nuclear mRNA quality control in yeast is mediated by Nrd1 co-transcriptional recruitment, as revealed by the targeting of Rho-induced aberrant transcripts. Nucleic Acids Research, Oxford University Press, 2011, 39 (7), pp.2809-2820. ⟨10.1093/nar/gkq1192⟩. ⟨hal-00602376⟩
  • Christine Mosrin-Huaman, Romy Honorine, A. Rachid Rahmouni. Expression of Bacterial Rho Factor in Yeast Identifies New Factors Involved in the Functional Interplay between Transcription and mRNP Biogenesis. Molecular and Cellular Biology, American Society for Microbiology, 2009, 29 (15), pp.4033-4044. ⟨10.1128/MCB.00272-09⟩. ⟨hal-00525149⟩
  • F. ToulmÉ, C. Mosrin-Huaman, I. Artsimovitch, A.R. Rahmouni. Transcriptional pausing in vivo: a nascent RNA hairpin restricts lateral movements of RNA polymerase in both forward and reverse directions. Journal of Molecular Biology, Elsevier, 2005, 351, pp.39-51. ⟨hal-00088714⟩
  • C. Mosrin-Huaman, C.L. Turnbough, A.R. Rahmouni. Translocation of Escherichia coli RNA polymerase against a protein roadblock in vivo highlights a passive sliding mechanism for transcript elongation. Molecular Microbiology, Wiley, 2004, 51, pp.1471-1481. ⟨hal-00113075⟩

 

NORMAND Thierry

 

email : thierry.normand@cnrs-orleans.fr

Téléphone : 02.38.25.55.86

Bureau A113

Maître de conférence au sein du Groupe thématique “Signalisation cellulaire”

 



20 documents

Article dans une revue

  • Amandine Serrano, Saïd El Haddad, Fréderic Moal, Thierry Prazuck, Eric Legac, et al.. Dysregulation of apoptosis and autophagy gene expression in peripheral blood mononuclear cells of efficiently treated HIV-infected patients. AIDS, Lippincott, Williams & Wilkins, 2018, 32 (12), pp.1579 - 1587. ⟨10.1097/QAD.0000000000001851⟩. ⟨hal-01936094⟩
  • Saïd El Haddad, Amandine Serrano, Thierry Normand, Chloé Robin, Martine Dubois, et al.. Interaction of Alpha-synuclein with Cytogaligin, a protein encoded by the proapoptotic gene GALIG. Biochemical and Biophysical Research Communications, Elsevier, 2018, 495 (1), pp.787-792. ⟨hal-01966108⟩
  • Lucile Mollet, Pauline Robinet, Martine Dubois, Axel Aurouet, Thierry Normand, et al.. Opposing Mcl-1, the GALIG proapoptotic gene is upregulated as neutrophils die and underexpressed in Acute Myeloid Leukemia cells.. Molecular Immunology, Elsevier, 2013, 56 (1-2), pp.123-8. ⟨10.1016/j.molimm.2013.04.012⟩. ⟨hal-00840170⟩
  • Pauline Robinet, Lucile Mollet, Patrick Gonzalez, Thierry Normand, Stephane Charpentier, et al.. The mitogaligin protein is addressed to the nucleus via a non-classical localization signal. Biochemical and Biophysical Research Communications, Elsevier, 2010, 392 (1), pp.53-57. ⟨10.1016/j.bbrc.2009.12.162⟩. ⟨hal-00529397⟩
  • Alexis D. Sennepin, Stéphane Charpentier, Thierry Normand, Cedric Sarre, Alain Legrand, et al.. Multiple reprobing of Western blots after inactivation of peroxidase activity by its substrate, hydrogen peroxide. Analytical Biochemistry, Elsevier Masson, 2009, 393 (1), pp.129-131. ⟨10.1016/j.ab.2009.06.004⟩. ⟨hal-00525339⟩
  • Patrick Gonzalez, Pauline Robinet, Stéphane Charpentier, Lucile Mollet, Thierry Normand, et al.. Apoptotic activity of a nuclear form of mitogaligin, a cell death protein. Biochemical and Biophysical Research Communications, Elsevier, 2009, 378 (4), pp.816-820. ⟨10.1016/j.bbrc.2008.11.133⟩. ⟨hal-00522444⟩
  • Patrick Gonzalez, Mélanie Duneau, Stéphane Charpentier, Thierry Normand, Lucile Mollet, et al.. Destabilization of Membranes Containing Cardiolipin or Its Precursors by Peptides Derived from Mitogaligin, a Cell Death Protein. Biochemistry, American Chemical Society, 2007, 46 (25), pp.7374-7382. ⟨10.1021/bi700213p⟩. ⟨hal-00159568⟩
  • M. Duneau, M. Boyer Guittaut, P. Gonzalez, S. Charpentier, T. Normand, et al.. Galig, a novel cell death gene that encodes a mitochondrial protein promoting cytochrome c release. Experimental Cell Research, Elsevier, 2005, 302, pp.194-205. ⟨hal-00088588⟩
  • Michaël Guittaut, Stéphane Charpentier, Thierry Normand, Martine Dubois, Jacques Raimond, et al.. Identification of an Internal Gene to the Human Galectin-3 Gene with Two Different Overlapping Reading Frames That Do Not Encode Galectin-3. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2001, 276 (4), pp.2652-2657. ⟨10.1074/jbc.m002523200⟩. ⟨hal-02137994⟩
  • J. Morissette, F. Durocher, J. Leblanc, T. Normand, F. Labrie, et al.. Genetic linkage mapping of the human steroid 5α-reductase type 2 gene (SRD5A2) close to D2S352 on chromosome region 2p23→p22. Cytogenetic and Genome Research, Karger, 1996, 73 (4), pp.304-307. ⟨10.1159/000134362⟩. ⟨hal-02160041⟩
  • J Adamski, Thierry Normand, F Leenders, D Monté, A. Bégué, et al.. Molecular cloning of a novel widely expressed human 80 kDa 17 β -hydroxysteroid dehydrogenase IV. Biochemical Journal, Portland Press, 1995, 311 (2), pp.437-443. ⟨10.1042/bj3110437⟩. ⟨hal-02160026⟩
  • Thierry Normand, B. Husen, F Leenders, H Pelczar, J.L Baert, et al.. Molecular characterization of mouse 17 beta-hydroxysteroid dehydrogenase IV.. Journal of Steroid Biochemistry and Molecular Biology, Elsevier, 1995, 55 (5-6), pp.541-8. ⟨10.1016/0960-0760(95)00204-9⟩. ⟨hal-02160020⟩
  • J Simard, Jean Feunteun, Gilbert Lenoir, T Tonin, Thierry Normand, et al.. Genetic mapping of the breast-ovarian cancer syndrome to a small interval on chromosome 17q12–21: exclusion of candidate genes EDH17B2 and RARA. Human Molecular Genetics, Oxford University Press (OUP), 1993, 2 (8), pp.1193-1199. ⟨10.1093/hmg/2.8.1193⟩. ⟨hal-02160208⟩
  • Thierry Normand, Steven Narod, Fernand Labrie, Jacques Simard. Detection of polymorphisms in the estradiol 17β-hydroxysteroid dehydrogenase II gene at the EDH17B2 locus on 17q11–q21. Human Molecular Genetics, Oxford University Press (OUP), 1993, 2 (4), pp.479-483. ⟨10.1093/hmg/2.4.479⟩. ⟨hal-02160210⟩
  • P Peeva, L Brun, M Ven Murthy, P Després, Thierry Normand, et al.. Adipose cell size and distribution in familial lipoprotein lipase deficiency.. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1992, 16 (10), pp.737-44. ⟨hal-02160233⟩
  • Thierry Normand, J. Bergeron, Teresa Fernandez-Margallo, A. Bharucha, R Ven Murthy, et al.. Geographic distribution and genealogy of mutation 207 of the lipoprotein lipase gene in the French Canadian population of Québec.. Human Genetics, Springer Verlag, 1992, 89 (6), pp.671-5. ⟨10.1007/BF00221960⟩. ⟨hal-02160222⟩
  • M. Bergeron, Thierry Normand, A. Bharucha, M Ven Murthy, P Julien, et al.. Prevalence, geographical distribution and genealogical investigations of mutation 188 of lipoprotein lipase gene in the French Canadian population of Québec.. Clinical Genetics, Wiley, 1992, 41 (4), pp.206-10. ⟨10.1111/j.1399-0004.1992.tb03664.x⟩. ⟨hal-02160230⟩
  • Y. Ma, Howard Henderson, V Murthy, Ghislaine Roederer, M. Monsalve, et al.. A Mutation in the Human Lipoprotein Lipase Gene as the Most Common Cause of Familial Chylomicronemia in French Canadians. New England Journal of Medicine, Massachusetts Medical Society, 1991, 324 (25), pp.1761-1766. ⟨10.1056/NEJM199106203242502⟩. ⟨hal-02160241⟩
  • Thierry Normand, Christiane Jean-Faucher, Claude Jean. Neonatal exposure to oestrogens alters the protein profiles and gene expression in the genital tract of adult male mice. Journal of Steroid Biochemistry, Elsevier, 1990, 36 (5), pp.415-423. ⟨10.1016/0022-4731(90)90082-4⟩. ⟨hal-02160254⟩
  • Thierry Normand, C. Jean-Faucher, C Jean. Developmental pattern of androgen-regulated proteins in seminal vesicles from the mouse.. International Journal of Andrology, Wiley, 1989, 12 (3), pp.219-30. ⟨hal-02160364⟩

MOLLET Lucile

 

email : lucile.mollet@cnrs-orleans.fr

Téléphone : 02.38.25.55.92

Bureau A114

Maître de conférence au sein du Groupe thématique “Signalisation cellulaire”

 



16 documents

Article dans une revue

  • Amandine Serrano, Saïd El Haddad, Fréderic Moal, Thierry Prazuck, Eric Legac, et al.. Dysregulation of apoptosis and autophagy gene expression in peripheral blood mononuclear cells of efficiently treated HIV-infected patients. AIDS, Lippincott, Williams & Wilkins, 2018, 32 (12), pp.1579 - 1587. ⟨10.1097/QAD.0000000000001851⟩. ⟨hal-01936094⟩
  • Sulayman Benmerzoug, Stéphanie Rose, Badreddine Bounab, David Gosset, Laure Duneau, et al.. STING-dependent sensing of self-DNA drives silica-induced lung inflammation. Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.5226. ⟨https://www.nature.com/articles/s41467-018-07425-1⟩. ⟨10.1038/s41467-018-07425-1⟩. ⟨hal-01975846⟩
  • Saïd El Haddad, Amandine Serrano, Thierry Normand, Chloé Robin, Martine Dubois, et al.. Interaction of Alpha-synuclein with Cytogaligin, a protein encoded by the proapoptotic gene GALIG. Biochemical and Biophysical Research Communications, Elsevier, 2018, 495 (1), pp.787-792. ⟨hal-01966108⟩
  • Lucile Mollet, Pauline Robinet, Martine Dubois, Axel Aurouet, Thierry Normand, et al.. Opposing Mcl-1, the GALIG proapoptotic gene is upregulated as neutrophils die and underexpressed in Acute Myeloid Leukemia cells.. Molecular Immunology, Elsevier, 2013, 56 (1-2), pp.123-8. ⟨10.1016/j.molimm.2013.04.012⟩. ⟨hal-00840170⟩
  • Pauline Robinet, Lucile Mollet, Patrick Gonzalez, Thierry Normand, Stephane Charpentier, et al.. The mitogaligin protein is addressed to the nucleus via a non-classical localization signal. Biochemical and Biophysical Research Communications, Elsevier, 2010, 392 (1), pp.53-57. ⟨10.1016/j.bbrc.2009.12.162⟩. ⟨hal-00529397⟩
  • Alexis D. Sennepin, Stéphane Charpentier, Thierry Normand, Cedric Sarre, Alain Legrand, et al.. Multiple reprobing of Western blots after inactivation of peroxidase activity by its substrate, hydrogen peroxide. Analytical Biochemistry, Elsevier Masson, 2009, 393 (1), pp.129-131. ⟨10.1016/j.ab.2009.06.004⟩. ⟨hal-00525339⟩
  • Patrick Gonzalez, Pauline Robinet, Stéphane Charpentier, Lucile Mollet, Thierry Normand, et al.. Apoptotic activity of a nuclear form of mitogaligin, a cell death protein. Biochemical and Biophysical Research Communications, Elsevier, 2009, 378 (4), pp.816-820. ⟨10.1016/j.bbrc.2008.11.133⟩. ⟨hal-00522444⟩
  • Patrick Gonzalez, Mélanie Duneau, Stéphane Charpentier, Thierry Normand, Lucile Mollet, et al.. Destabilization of Membranes Containing Cardiolipin or Its Precursors by Peptides Derived from Mitogaligin, a Cell Death Protein. Biochemistry, American Chemical Society, 2007, 46 (25), pp.7374-7382. ⟨10.1021/bi700213p⟩. ⟨hal-00159568⟩
  • Clarisse Lorin, Lucile Mollet, Frédéric Delebecque, Chantal Combredet, Bruno Hurtrel, et al.. A Single Injection of Recombinant Measles Virus Vaccines Expressing Human Immunodeficiency Virus (HIV) Type 1 Clade B Envelope Glycoproteins Induces Neutralizing Antibodies and Cellular Immune Responses to HIV. Journal of Virology, American Society for Microbiology, 2004, 78 (1), pp.146-157. ⟨10.1128/jvi.78.1.146-157.2004⟩. ⟨hal-02129907⟩
  • Chantal Combredet, Valérie Labrousse, Lucile Mollet, Clarisse Lorin, Frédéric Delebecque, et al.. A Molecularly Cloned Schwarz Strain of Measles Virus Vaccine Induces Strong Immune Responses in Macaques and Transgenic Mice. Journal of Virology, American Society for Microbiology, 2003, 77 (21), pp.11546-11554. ⟨10.1128/jvi.77.21.11546-11554.2003⟩. ⟨hal-02129918⟩
  • Lucile Mollet, T.S Li, A. Samri, C Tournay, R. Tubiana, et al.. Dynamics of HIV-specific CD8+ T lymphocytes with changes in viral load.The RESTIM and COMET Study Groups.. Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2000, 165 (3), pp.1692-704. ⟨hal-02129938⟩
  • F Hadida, V Vieillard, Lucile Mollet, I Clark-Lewis, M Baggiolini, et al.. Cutting edge: RANTES regulates Fas ligand expression and killing by HIV-specific CD8 cytotoxic T cells.. Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 1999, 163 (3), pp.1105-9. ⟨hal-02129966⟩
  • Lucile Mollet, B. Fautrel, V. Leblond, F. Bergeron, H Merle-Béral, et al.. Leukemic CD3+ LGL share functional properties with their CD8+ CD57+ cell counterpart expanded after BMT.. Leukemia, Nature Publishing Group: Open Access Hybrid Model Option B, 1999, 13 (2), pp.230-40. ⟨hal-02129951⟩
  • Lucile Mollet, B Sadat-Sowti, J Duntze, V. Leblond, F. Bergeron, et al.. CD8hi+CD57+ T lymphocytes are enriched in antigen-specific T cells capable of down-modulating cytotoxic activity. International Immunology, Oxford University Press (OUP), 1998, 10 (3), pp.311-323. ⟨10.1093/intimm/10.3.311⟩. ⟨hal-02129977⟩
  • Behazine Sadat-Sowti, Patrice Debre, Lucile Mollet, Laurent Quint, Fabienne Hadida, et al.. An inhibitor of cytotoxic functions produced by CD8+CD57+ T lymphocytes from patients suffering from AIDS and immunosuppressed bone marrow recipients. European Journal of Immunology, Wiley-VCH Verlag, 1994, 24 (11), pp.2882-2888. ⟨10.1002/eji.1830241145⟩. ⟨hal-02129985⟩

Brevet

  • Frédéricic Tangy, Clarisse Lorin, Lucile Mollet, Frédéric Delebecque. Recombinant measles viruses expressing epitopes of antigens of RNA viruses - use for the preparation of vaccine compositions.. France, Patent n° : WO2004001051. 2004. ⟨hal-02130007⟩

VALLÉE-MEHEUST Béatrice

 

email : beatrice.vallee@cnrs-orleans.fr

Téléphone : 02.38.25.76.11

Bureau D113

Chargée de recherche au sein du Groupe thématique “Signalisation cellulaire”

 



17 documents

Article dans une revue

  • Julie Tastet, Hélène Cuberos, Béatrice Vallée, Annick Toutain, Martine Raynaud, et al.. LIMK2-1 is a Hominidae-Specific Isoform of LIMK2 Expressed in Central Nervous System and Associated with Intellectual Disability. Neuroscience, Elsevier - International Brain Research Organization, 2019, 399, pp.199-210. ⟨10.1016/j.neuroscience.2018.12.017⟩. ⟨hal-02067472⟩
  • Béatrice Vallée, Hélène Cuberos, Michel Doudeau, Fabienne Godin, David Gosset, et al.. LIMK2-1, a new isoform of human LIMK2, regulates actin cytoskeleton remodeling via a different signaling pathway than that of its two homologs, LIMK2a and LIMK2b. Biochemical Journal, Portland Press, 2018, 475 (23), pp.3745-3761. ⟨hal-01966439⟩
  • H. Cuberos, B. VallÉe, P. Vourc'H, J. Tastet, C.R. Andres, et al.. Roles of LIM kinases in central nervous system function and dysfunction. FEBS Letters, Wiley, 2015, 589 (24PartB), pp.3795-3806. ⟨10.1016/j.febslet.2015.10.032⟩. ⟨hal-02072231⟩
  • Martine Beaufour, Fabienne Godin, Béatrice Vallée, Martine Cadene, Hélène Bénédetti. Interaction Proteomics Suggests a New Role for the Tfs1 Protein in Yeast.. Journal of Proteome Research, American Chemical Society, 2012, 11 (6), pp.3211-3218. ⟨10.1021/pr201239t⟩. ⟨hal-00721771⟩
  • Béatrice Vallée, Michel Doudeau, Fabienne Godin, Aurélie Gombault, Aurélie Tchalikian, et al.. Nf1 RasGAP inhibition of LIMK2 mediates a new cross-talk between Ras and Rho pathways.. PLoS ONE, Public Library of Science, 2012, 7 (10), pp.e47283. ⟨10.1371/journal.pone.0047283⟩. ⟨hal-00817355⟩
  • Julie Tastet, Patrick Vourc'H, Frédéric Laumonnier, Béatrice Vallée, Carole Michelle, et al.. LIMK2d, a truncated isoform of Lim kinase 2 regulates neurite growth in absence of the LIM kinase domain. Biochemical and Biophysical Research Communications, Elsevier, 2012, 420 (2), pp.247-252. ⟨10.1016/j.bbrc.2012.02.134⟩. ⟨hal-01136281⟩
  • Fabienne Godin, Sandrine Villette, Béatrice Vallée, Michel Doudeau, Séverine Morisset-Lopez, et al.. A fraction of neurofibromin interacts with PML bodies in the nucleus of the CCF astrocytoma cell line.. Biochemical and Biophysical Research Communications, Elsevier, 2012, 418 (4), pp.689-94. ⟨10.1016/j.bbrc.2012.01.079⟩. ⟨hal-00721861⟩
  • Aurélie Gombault, Jonas Warringer, Robert Caesar, Fabienne Godin, Béatrice Vallée, et al.. A phenotypic study of TFS1 mutants differentially altered in the inhibition of Ira2p or CPY. FEMS Yeast Research, Oxford University Press (OUP), 2009, 9 (6), pp.867-874. ⟨10.1111/j.1567-1364.2009.00535.x⟩. ⟨hal-00522432⟩
  • Aurélie Gombault, Fabienne Godin, Denise Sy, Baptiste Legrand, Hélène Chautard, et al.. Molecular Basis of the Tfs1/Ira2 Interaction: A Combined Protein Engineering and Molecular Modelling Study. Journal of Molecular Biology, Elsevier, 2007, 374 (3), pp.604-617. ⟨10.1016/j.jmb.2007.09.057⟩. ⟨hal-00181161⟩
  • Béatrice Vallée, H. Riezman. Lip 1p: a novel subunit of acyl-CoA ceramide synthase. EMBO Journal, EMBO Press, 2005, 24, pp.730-741. ⟨hal-00088715⟩
  • Béatrice Vallée, G Coadou, H. Labbé, D. Sy, F. Vovelle, et al.. Peptides corresponding to the N- and C-terminal parts of PEBP are well-structured in solution: new insights into their possible interaction with partners in vivo.. Journal of Peptide Research, Wiley-Blackwell, 2003, 61 (2), pp.47-57. ⟨hal-02118669⟩
  • Kouichi Funato, Ruben Lombardi, Béatrice Vallée, Howard Riezman. Lcb4p Is a Key Regulator of Ceramide Synthesis from Exogenous Long Chain Sphingoid Base in Saccharomyces cerevisiae. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2003, 278 (9), pp.7325-7334. ⟨10.1074/jbc.M209925200⟩. ⟨hal-02118660⟩
  • Kouichi Funato, Béatrice Vallée, Howard Riezman. Biosynthesis and Trafficking of Sphingolipids in the Yeast Saccharomyces cerevisiae †. Biochemistry, American Chemical Society, 2002, 41 (51), pp.15105-15114. ⟨10.1021/bi026616d⟩. ⟨hal-02118664⟩
  • D Schorling, Béatrice Vallée, Wolfgang Barz, Howard Riezman, Dieter Oesterhelt. Lag1p and Lac1p Are Essential for the Acyl-CoA–dependent Ceramide Synthase Reaction in Saccharomyces cerevisae. Molecular Biology of the Cell, American Society for Cell Biology, 2001, 12 (11), pp.3417-3427. ⟨10.1091/mbc.12.11.3417⟩. ⟨hal-02118674⟩
  • Béatrice Vallée, P Tauc, J Brochon, M Maget-Dana, D. Lelièvre, et al.. Behaviour of bovine phosphatidylethanolamine-binding protein with model membranes. Evidence of affinity for negatively charged membranes.. European Journal of Biochemistry, Wiley, 2001, 268 (22), pp.5831-41. ⟨hal-02118681⟩
  • Béatrice Vallée, C. Teyssier, R. Maget-Dana, J. Ramstein, N. Bureaud, et al.. Stability and physicochemical properties of the bovine brain phosphatidylethanolamine-binding protein.. European Journal of Biochemistry, Wiley, 1999, 266 (1), pp.40-52. ⟨hal-02118686⟩
  • C. Serre, Béatrice Vallée, N. Bureaud, F. Schoentgen, C. Zelwer. Crystal structure of the phosphatidylethanolamine-binding protein from bovine brain: a novel structural class of phospholipid-binding proteins.. Structure, Elsevier (Cell Press), 1998, 6 (10), pp.1255-65. ⟨hal-02118689⟩

LEGRAND Alain

 

email : alain.legrand@cnrs-orleans.fr

Téléphone : 02.38.25.55.36

Bureau A114

Professeur et co-Responsable du Groupe thématique “Signalisation cellulaire”

 



37 documents

Article dans une revue

  • Amandine Serrano, Saïd El Haddad, Fréderic Moal, Thierry Prazuck, Eric Legac, et al.. Dysregulation of apoptosis and autophagy gene expression in peripheral blood mononuclear cells of efficiently treated HIV-infected patients. AIDS, Lippincott, Williams & Wilkins, 2018, 32 (12), pp.1579 - 1587. ⟨10.1097/QAD.0000000000001851⟩. ⟨hal-01936094⟩
  • Saïd El Haddad, Amandine Serrano, Thierry Normand, Chloé Robin, Martine Dubois, et al.. Interaction of Alpha-synuclein with Cytogaligin, a protein encoded by the proapoptotic gene GALIG. Biochemical and Biophysical Research Communications, Elsevier, 2018, 495 (1), pp.787-792. ⟨hal-01966108⟩
  • Kévin Moreau, Justine Surand, Aurélia Le Dantec, Christine Mosrin-Huaman, Alain Legrand, et al.. Recombinant yeast and human cells as screening tools to search for antibacterial agents targeting the transcription termination factor Rho. Journal of Antibiotics, Nature Publishing Group: Open Access Hybrid Model Option B, 2018, 71 (4), pp.447-455. ⟨hal-01966171⟩
  • Lucile Mollet, Pauline Robinet, Martine Dubois, Axel Aurouet, Thierry Normand, et al.. Opposing Mcl-1, the GALIG proapoptotic gene is upregulated as neutrophils die and underexpressed in Acute Myeloid Leukemia cells.. Molecular Immunology, Elsevier, 2013, 56 (1-2), pp.123-8. ⟨10.1016/j.molimm.2013.04.012⟩. ⟨hal-00840170⟩
  • Violette Senille, Dominique Lelievre, Françoise Paquet, Norbert Garnier, Ned Lamb, et al.. The addressing fragment of mitogaligin: first insights into functional and structural properties.. ChemBioChem, Wiley-VCH Verlag, 2013, 14 (6), pp.711-20. ⟨10.1002/cbic.201200715⟩. ⟨hal-00817503⟩
  • Pauline Robinet, Lucile Mollet, Patrick Gonzalez, Thierry Normand, Stephane Charpentier, et al.. The mitogaligin protein is addressed to the nucleus via a non-classical localization signal. Biochemical and Biophysical Research Communications, Elsevier, 2010, 392 (1), pp.53-57. ⟨10.1016/j.bbrc.2009.12.162⟩. ⟨hal-00529397⟩
  • Alexis D. Sennepin, Stéphane Charpentier, Thierry Normand, Cedric Sarre, Alain Legrand, et al.. Multiple reprobing of Western blots after inactivation of peroxidase activity by its substrate, hydrogen peroxide. Analytical Biochemistry, Elsevier Masson, 2009, 393 (1), pp.129-131. ⟨10.1016/j.ab.2009.06.004⟩. ⟨hal-00525339⟩
  • Patrick Gonzalez, Pauline Robinet, Stéphane Charpentier, Lucile Mollet, Thierry Normand, et al.. Apoptotic activity of a nuclear form of mitogaligin, a cell death protein. Biochemical and Biophysical Research Communications, Elsevier, 2009, 378 (4), pp.816-820. ⟨10.1016/j.bbrc.2008.11.133⟩. ⟨hal-00522444⟩
  • Valerie Boutin, Alain Legrand, Roger Mayer, Maurice Nachtigal, Michel Monsigny, et al.. Glycofection: The Ubiquitous Roles of Sugar Bound on Glycoplexes. Drug Delivery, Taylor & Francis, 2008, 6 (1), pp.45-50. ⟨10.1080/107175499267156⟩. ⟨hal-02138035⟩
  • Patrick Gonzalez, Mélanie Duneau, Stéphane Charpentier, Thierry Normand, Lucile Mollet, et al.. Destabilization of Membranes Containing Cardiolipin or Its Precursors by Peptides Derived from Mitogaligin, a Cell Death Protein. Biochemistry, American Chemical Society, 2007, 46 (25), pp.7374-7382. ⟨10.1021/bi700213p⟩. ⟨hal-00159568⟩
  • M. Duneau, M. Boyer Guittaut, P. Gonzalez, S. Charpentier, T. Normand, et al.. Galig, a novel cell death gene that encodes a mitochondrial protein promoting cytochrome c release. Experimental Cell Research, Elsevier, 2005, 302, pp.194-205. ⟨hal-00088588⟩
  • Michaël Guittaut, Stéphane Charpentier, Thierry Normand, Martine Dubois, Jacques Raimond, et al.. Identification of an Internal Gene to the Human Galectin-3 Gene with Two Different Overlapping Reading Frames That Do Not Encode Galectin-3. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2001, 276 (4), pp.2652-2657. ⟨10.1074/jbc.m002523200⟩. ⟨hal-02137994⟩
  • S. Fogel, M. Guittaut, Alain Legrand, M. Monsigny, E. Hebert. The Tat protein of HIV-1 induces galectin-3 expression. Glycobiology, Oxford University Press (OUP), 1999, 9 (4), pp.383-387. ⟨10.1093/glycob/9.4.383⟩. ⟨hal-02138044⟩
  • V. Carrière, V. Piller, Alain Legrand, M. Monsigny, A.C. Roche. The sugar binding activity of MR60, a mannose-specific shuttling lectin, requires a dimeric state. Glycobiology, Oxford University Press (OUP), 1999, 9 (10), pp.995-1002. ⟨10.1093/glycob/9.10.995⟩. ⟨hal-02138032⟩
  • C Arar, J.C Gaudin, L Capron, Alain Legrand. Galectin-3 gene (LGALS3) expression in experimental atherosclerosis and cultured smooth muscle cells.. FEBS Letters, Wiley, 1998, 430 (3), pp.307-311. ⟨hal-02138144⟩
  • Alain Legrand, Drazen B. Jimonjic, Nicolae C. Popescu, Maurice Nachtigal. A Chromosome 4 Satellite I DNA Isolated from SV40-Transformed Human Cells. DNA Research, Oxford University Press (OUP), 1998, 5 (5), pp.271-276. ⟨10.1093/dnares/5.5.271⟩. ⟨hal-02138074⟩
  • Alain Legrand, E.P Mayer, S Dalvi, M Nachtigal. Transformation of rabbit vascular smooth muscle cells by human cytomegalovirus morphological transforming region I.. American Journal of Pathology, American Society for Investigative Pathology, 1997, 151 (5), pp.1387-95. ⟨hal-02138369⟩
  • Jean-Charles Gaudin, Chantal Arar, Michel Monsigny, Alain Legrand. Modulation of the expression of the rabbit galectin-3 gene by p53 and c-Ha-ras proteins and PMA. Glycobiology, Oxford University Press (OUP), 1997, 7 (8), pp.1089-1098. ⟨10.1093/glycob/7.8.1089⟩. ⟨hal-02138352⟩
  • J. Raimond, D Zimonjic, C. Mignon, M. Mattei, N Popescu, et al.. Mapping of the galectin-3 gene (LGALS3) to human chromosome 14 at region 14q21-22.. Mammalian Genome, Springer Verlag, 1997, 8 (9), pp.706-707. ⟨hal-02138375⟩
  • V Vergé, Alain Legrand, T Hévor. Isolation of carbohydrate metabolic clones from cultured astrocytes. Glia, Wiley, 1996, 18 (3), pp.244-254. 3.0.CO;2-Z">⟨10.1002/(SICI)1098-1136(199611)18:3<244::AID-GLIA8>3.0.CO;2-Z⟩. ⟨hal-02138380⟩
  • C Arar, C. Mignon, M. Mattei, M. Monsigny, Alexis Roche, et al.. Mapping of the MR60/ERGIC-53 gene to human chromosome 18q21.3-18q22 by in situ hybridization.. Mammalian Genome, Springer Verlag, 1996, 7 (10), pp.791-2. ⟨10.1007/s003359900238⟩. ⟨hal-02138384⟩
  • J-C Gaudin, M. Monsigny, Alain Legrand. Cloning of the cDNA encoding rabbit galectin-3.. Gene, Elsevier, 1995, 163 (2), pp.249-52. ⟨10.1016/0378-1119(95)00388-M⟩. ⟨hal-02138396⟩
  • J Raimond, F Rouleux, M. Monsigny, Alain Legrand. The second intron of the human galectin-3 gene has a strong promoter activity down-regulated by p53.. FEBS Letters, Wiley, 1995, 363 (1-2), pp.165-9. ⟨10.1016/0014-5793(95)00310-6⟩. ⟨hal-02138402⟩
  • Chantal Arar, Valérie Carpentier, Jean-Pierre Le Caer, Michel Monsigny, Alain Legrand, et al.. ERGIC-53, a Membrane Protein of the Endoplasmic Reticulum-Golgi Intermediate Compartment, Is Identical to MR60, an Intracellular Mannose-specific Lectin of Myelomonocytic Cells. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1995, 270 (8), pp.3551-3553. ⟨10.1074/jbc.270.8.3551⟩. ⟨hal-02138409⟩
  • F Rouleux-Bonnin, M. Monsigny, Alain Legrand. Transcriptional expression of mannose receptor gene during differentiation of human macrophages.. Biochemical and Biophysical Research Communications, Elsevier, 1995, 217 (1), pp.106-12. ⟨hal-02138393⟩
  • Florence Rouleux, Michel Monsigny, Alain Legrand. A Negative Regulatory Element of the Macrophage-Specific Human Mannose Receptor Gene Represses Its Expression in Nonmyeloid Cells. Experimental Cell Research, Elsevier, 1994, 214 (1), pp.113-119. ⟨10.1006/excr.1994.1239⟩. ⟨hal-02138011⟩
  • J. Raimond, C. Plessis, F. Fargette, Alain Legrand, E. Hebert. An EBV-Based Vector Allowing a High Level of LTRHIV-Directed Expression in Human Cells. Plasmid, Elsevier, 1994, 32 (1), pp.70-74. ⟨10.1006/plas.1994.1045⟩. ⟨hal-02138444⟩
  • Patrick Midoux, Christina Mendes, Alain Legrand, Jacques Raimond, Roger Mayer, et al.. Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells. Nucleic Acids Research, Oxford University Press, 1993, 21 (4), pp.871-878. ⟨10.1093/nar/21.4.871⟩. ⟨hal-02138456⟩
  • N Bizouarne, V. Denis, Alain Legrand, M. Monsigny, C. Kieda. A SV-40 immortalized murine endothelial cell line from peripheral lymph node high endothelium expresses a new alpha-L-fucose binding protein.. Biology of the Cell, Wiley, 1993, 79 (3), pp.209-18. ⟨10.1016/0248-4900(93)90139-6⟩. ⟨hal-02138452⟩
  • Alain Legrand, P Greenspan, M Nagpal, S Nachtigal, M Nachtigal. Characterization of human vascular smooth muscle cells transformed by the early genetic region of SV40 virus.. American Journal of Pathology, American Society for Investigative Pathology, 1991, 139 (3), pp.629-640. ⟨hal-02138458⟩
  • Alain Legrand, Maurice Nachtigal. Homologous Recombination of a Plasmid Containing the SV40 Early Region in Rabbit Cells. Intervirology, Karger, 1991, 32 (3), pp.173-184. ⟨10.1159/000150197⟩. ⟨hal-02138462⟩
  • M Nachtigal, Alain Legrand, M Nagpal, S Nachtigal, P Greenspan. Transformation of rabbit vascular smooth muscle cells by transfection with the early region of SV40 DNA.. American Journal of Pathology, American Society for Investigative Pathology, 1990, 136 (2), pp.297-306. ⟨hal-02138474⟩
  • M. Nachtigal, Alain Legrand, P. Greenspan, S Nachtigal, M. Nagpal. Immortalization of Rabbit Vascular Smooth Muscle Cells after Transfection with a Fragment of the BglII N Region of Herpes Simplex Virus Type 2 DNA. Intervirology, Karger, 1990, 31 (2-4), pp.166-174. ⟨10.1159/000150151⟩. ⟨hal-02138469⟩
  • M Nachtigal, M Nagpal, P Greenspan, A Nachtigal, Alain Legrand. Characterization of a continuous smooth muscle cell line derived from rabbit aorta.. In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1989, 25 (10), pp.892-8. ⟨10.1007/BF02624001⟩. ⟨hal-02138476⟩
  • C. Nicolau, Alain Legrand, E. Grosse. Liposomes as carriers for in vivo gene transfer and expression.. Methods in Enzymology, Elsevier, 1987, 149, pp.157-76. ⟨10.1016/0076-6879(87)49054-X⟩. ⟨hal-02138481⟩
  • P Nandi, Alain Legrand, C. Nicolau. Biologically active, recombinant DNA in clathrin-coated vesicles isolated from rat livers after in vivo injection of liposome-encapsulated DNA.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1986, 261 (35), pp.16722-6. ⟨hal-02138484⟩
  • P. Soriano, J Dijkstra, Alain Legrand, H. Spanjer, D. Londos-Gagliardi, et al.. Targeted and nontargeted liposomes for in vivo transfer to rat liver cells of a plasmid containing the preproinsulin I gene.. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 1983, 80 (23), pp.7128-7131. ⟨10.1073/pnas.80.23.7128⟩. ⟨hal-02138490⟩