Accueil > Publications > Recherche par années > Années 1990 > 1991

Asseline, U ; Thuong, NT

Synthesis of oligonucleotides covalently linked to intercalating agents and to reactive groups

Nucleosides & Nucleotides 10 (1-3) 359-362

par Administrateur - publié le

Abstract :

The use of modified supports involving 2,2’-dithiodiethanol allows solid-phase synthesis of oligonucleotides derivatized at their 3’ end with an acridine or a phenanthroline derivative or with phosphate, thiophosphate and amino group.