Accueil > Publications > Recherche par années > Années 1990 > 1993

Guihard, G ; Benedetti, H ; Besnard, M ; Letellier, L

Phosphate efflux through the channels formed by colicins and phage t5 in escherichia-coli-cells is responsible for the fall in cytoplasmic atp

Journal of Biological Chemistry 268 (24) 17775-17780

par Administrateur - publié le

Abstract :

Previous studies have shown that channel formation in the cytoplasmic membrane of Escherichia coli by colicin A and phage T5 leads to an efflux of cytoplasmic potassium and to a membrane depolarization. Here we show that upon opening of these channels, the intracellular ATP concentration is decreased to 10% of its original value in