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Roig, V ; Kurfurst, R ; Thuong, NT

Oligo- ?-deoxyribonucleotides and oligo- ?-deoxyribonucleotides involving 2-aminopurine and guanine for triple-helix formation

Tetrahedron Letters 34 (10) 1601-1604

par Administrateur - publié le

Abstract :

Purine oligo-ß-deoxyribonucleotides and unnatural nuclease-resistant a-anomer derivatives were constructed with 2-aminopurine (amP) and guanine (G) in order to recognize purine sequences in double-helical DNA via isomorphous base triplets amP.AT and G.GC.