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Tegoni, M ; White, SA ; Roussel, A ; Mathews, FS ; Cambillau, C

A hypothetical complex between crystalline flavocytochrome-B(2) and cytochrome-C

Proteins-Structure Function and Genetics 16 (4) 408-422

par Administrateur - publié le

Abstract :

Flavocytochrome b2 and cytochrome c are physiological electron transfer partners in yeast mitochondria. The formation of a stable complex between them has been demonstrated both in solution and in the crystalline state. On the basis of the three-dimensional structures, using molecular modeling and energy minimization, we have generated a hypothetical model for the interaction of these redox partners in the crystal lattice.