Accueil > Publications > Recherche par années > Années 1990 > 1995

Magetdana, R ; Bonmatin, JM ; Hetru, C ; Ptak, M ; Maurizot, JC

The secondary structure of the insect defensin-A depends on its environment - a circular-dichroism study

Biochimie 77 (4) 240-244

par Administrateur - publié le

Abstract :

Defensin A is an inducible antibacterial protein isolated from the larvae of Phormia terranovae. The conformation of defensin A has been previously determined by two-dimensional(1)H-NMR for concentrations in the range of 4-8 mM in water (Bonmatin JM et al (1992)J Biomol NMR 2, 235-256). CD spectroscopic data of defensin A at lower concentrations (10(-5) to 10(-3) M) are reported herein. The ellipticity in the 200-240 nm wavelength range for various solvents varies as follows : acetonitrile