Accueil > Publications > Recherche par années > Années 1990 > 1997

Pousset, D ; Piller, V ; Bureaud, N ; Monsigny, M ; Piller, F

Increased alpha 2,6 sialylation of N-glycans in a transgenic mouse model of hepatocellular carcinoma

Cancer Research 57 (19) 4249-4256

par Administrateur - publié le

Abstract :

Liver cancer is one of the most frequent and lethal malignancies worldwide, Early detection is hampered by the absence of reliable markers, Mice transgenic for the SV40 large T antigen under the control of a liver-specific promoter spontaneously develop well-differentiated hepatocellular carcinomas between 8 to 10 weeks of age.