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Accueil > Publications > Recherche par années > Années 1990 > 1998

Mosrin-Huaman, C ; Canaple, L ; Locker, D ; Decoville, M

DSP1 gene of Drosophila melanogaster encodes an HMG-domain protein that plays multiple roles in development

Developmental Genetics 23 (4) 324-334

par Administrateur - publié le

Abstract :

DSP1 is an HMG-box containing protein of Drosophila melanogaster which was first identified as a co-repressor of the Dorsal protein. Recently, the analysis of the structure of the gene has led vs to propose that DSP1 is the Drosophila equivalent of the ubiquitous vertebrate HMG 1/2 proteins. In the present paper, the patterns of expression of DSP1 protein and RNA in adult flies and during development are reported. in the adults DSP1 protein is located in nurse cells of ovaries and in brain. During eggs development uniform expression of DSP1 protein persists until the end of germband retraction.