Accueil > Publications > Recherche par années > Années 1990 > 1998

Morel, N ; Buryi, V ; Feron, O ; Gomez, JP ; Christen, MO ; Godfraind,T

The action of calcium channel blockers on recombinant L-type calcium channel a1-subunits

British Journal of Pharmacology 125 1005-1012

par Administrateur - publié le

Abstract :

1 CHO cells expressing the alpha(1C-a), subunit (cardiac isoform) and the alpha(1C-b) subunit (vascular isoform) of the voltage-dependent L-type Ca2+ channel were used to investigate whether tissue selectivity of Ca2+ channel blockers could be related to different affinities for ale isoforms.