Accueil > Publications > Recherche par années > Années 1990 > 1998

Toth, E ; Merbach, AE

Water exchange dynamics : The key for high relaxivity contrast agents in medical magnetic resonance imaging

Ach-Models in Chemistry 135 (5) 873-884

par Administrateur - publié le

Abstract :

Current developments in medical Magnetic Resonance Imaging (MRI) call for very-high-relaxivity contrast agents. The dynamic parameters governing the relaxivity of today’s (poly(amino carboxylate) complexes of Gd3+ (or other paramagnetic metals) are mainly the rates of molecular tumbling (1/tau(R)), of the exchange of the inner sphere water molecule(s) (1/tau(m)), and of electronic relaxation (1/T-1,T-2e).