Accueil > Publications > Recherche par années > Années 2000 > 2000

Landon, C ; Pajon, A ; Vovelle, F ; Sodano, P

The active site of drosomycin, a small insect antifungal protein, delineated by comparison with the modeled structure of Rs-AFP2, a plant antifungal protein

Journal of Peptide Research 56 (4) 231-238

par Administrateur - publié le

Abstract :

Drosomycin is the first strictly antifungal protein isolated from an insect (Drosophila melanogaster). The solution structure of this 44-residue protein has been reported previously. It involves a three-stranded ß-sheet and an a-helix, the protein global fold being maintained by four disulfide bridges. Rs-AFP2 is a plant antifungal protein exhibiting 41% sequence similarity with drosomycin.