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Ziegler, A ; Gillet, B ; Beloeil, JC ; Macher, JP ; Decorps, M ; Nedelec, JF

Localized 2D correlation spectroscopy in human brain at 3 T

Magnetic Resonance Materials in Physics Biology and Medicine 14 (1) 45-49

par Administrateur - publié le

Abstract :

The purpose of this study was to acquire a localized 2D (two-dimensional) H-1 correlation spectrum. in a volume of interest reasonably small, and within an experiment time compatible with clinical applications. A modified PRESS technique has been used. The last 180degrees pulse of the PRESS sequence has been converted into a 90degrees pulse for both refocusing and coherence transfer. 2D correlation spectroscopy was performed on healthy volunteers in a clinical magnet, at 3 T, within 34 min, for a voxel size of 27 cm(3). This result makes it possible to consider clinical applications. (C) 2002 Elsevier Science B.V. All rights reserved.