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Meric, P ; Autret, G ; Doan, BT ; Gillet, B ; Sebrie, C ; Beloeil, JC

In vivo 2D magnetic resonance spectroscopy of small animals

Magnetic Resonance Materials in Physics Biology and Medicine 17 (3-6) 317-338

par Administrateur - publié le

Abstract :

Localized in vivo NMR spectroscopy, chemical shift imaging or multi-voxel spectroscopy are potentially useful tools in small animals that are complementary to MRI, adding biochemical information to the mainly anatomical data provided by imaging of water protons. However the contribution of such methods remains hampered by the low spectral resolution of the in vivo I D spectra. Two-dimensional methods widely developed for in vitro studies have been proposed as suitable approaches to overcome these limitations in resolution.