Accueil > Publications > Recherche par années > Années 2000 > 2006

Smirnov, P ; Gazeau, F ; Beloeil, JC ; Doan, BT ; Wilhelm, C ; Gillet, B

Single-cell detection by gradient echo 9.4 T MRI : a parametric study

Contrast Media & Molecular Imaging 1 (4) 165-174

par Administrateur - publié le

Abstract :

Recent studies have shown that cell migration can be monitored in vivo by magnetic resonance imaging after intracellular contrast agent incorporation. This is due to the dephasing effect on proton magnetization of the local magnetic field created by a labelled cell. Anionic iron oxide nanoparticles (AMNP) are among the most efficient and non-toxic contrast agents to be spontaneously taken up by a wide variety of cells.