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Burai, L ; Hietapelto, V ; Kiraly, R ; Toth, E ; Brucher, E

Stability constants and H-1 relaxation effects of ternary complexes formed between Gd-DTPA, Gd-DTPA-BMA, Gd-DOTA, and Gd-EDTA and citrate, phosphate, and carbonate ions

Magnetic Resonance in Medicine 38 (1) 146-150

par Administrateur - publié le

Abstract :

Formation of ternary complexes between Gd-DTPA, Gd-DTPA-BMA, and Gd-DOTA, used as contrast enhancement agents in MRI and the endogenously available carbonate and phosphate ions, has been demonstrated. The extent of ternary complex formation and its effect on the proton relaxation, measured at 9 MHz, rates is negligible at around pH