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Isaac M., Pallier A., Szeremeta F., Bayle P.-A., Barantin L., Bonnet C. S. and Seneque O

MRI and luminescence detection of Zn2+ with a lanthanide complex-zinc finger peptide conjugate

Chemical Communications (2018) 54 (53) 7350-53

par Frapart - publié le

Abstract :

A bioinspired probe based on a zinc finger peptide functionalized by a lanthanide(iii)-DOTA monoamide complex turns out to be active for both luminescence and MRI detection of Zn2+, depending on the lanthanide cation. A mechanism for MRI-based detection is proposed.