NMR Platform

NMR analyses performed on 400/600/700 MHz spectrometers

For any spectral request, contact Hervé MEUDAL, technical manager - +33 2.38.25.55.46 or 55.63

For any collaborative project application on 700MHz / 600MHz or 400MHz spectrometers, contact Karine LOTH, scientific manager - Tel : +33 2 38 25 55 71

Nuclear Magnetic Resonance is a highly efficient technique to analyze molecules at the atomic scale, thanks to magnetic properties of some of their nuclei (mainly 1H, 13C, 15N, 31P, 17O) – hence the name “nuclear”.
Autonomous users book time to acquire spectra themselves. Moreover, this facility is open to all members of the scientific community - both academic and privately-funded. In that case, an engineer is available in order to advise, to optimize and to realize the experiments.
Currently, the main requests are related to:
- Checking quality/purity of the products, stability and/or fold
- Follow up of organic synthesis
- Analyzing a large diversity of biomolecules: peptides/proteins, glycoproteins, nucleic acids, polymers…
- Characterizing contrast agents for medical imaging

Experimental facilities
  BRUKER 600MHz equipped with a 5mm probe for chemistry (31P-15N and 19F), a 5mm inverse probe for structural biology, and a sample case.
  BRUKER 700MHz equipped with a 5mm cryoprobe for structural biology
  BRUKER 400MHz equipped with a 10mm probe (31P-109Ag) and a 5mm (31P-15N and 19F) for development of contrast agents.