Publications

Aanchal Mishra, Stéphane Goffinont, Franck Coste, El Hadji Cisse, Lucija Mance, et al.. Fusion Protein‐Assisted Crystallization of Human SUMO1. Proteins - Structure, Function and Bioinformatics, 2025, ⟨10.1002/prot.26838⟩. ⟨hal-05082034⟩

Franck Coste, Aanchal Mishra, Catherine Chapuis, Lucija Mance, Zofia Pukało, et al.. RING dimerisation drives higher-order organisation of SINA/SIAH E3 ubiquitin ligases. FEBS Journal, 2025, ⟨10.1111/febs.70000⟩. ⟨hal-04931763⟩

Mohammed Bergoug, Christine Mosrin-Huaman, Amandine Serrano, Fabienne Godin, Michel Doudeau, et al.. An Atypical Mechanism of SUMOylation of Neurofibromin SecPH Domain Provides New Insights into SUMOylation Site Selection. Journal of Molecular Biology, 2024, 436 (22), pp.168768. ⟨10.1016/j.jmb.2024.168768⟩. ⟨hal-04771131⟩

Lucija Mance, Nicolas Bigot, Edison Zhamungui Sánchez, Franck Coste, Natalia Martín-González, et al.. Dynamic BTB-domain filaments promote clustering of ZBTB proteins. Molecular Cell, 2024, 84 (13), pp.2490-2510.e9. ⟨10.1016/j.molcel.2024.05.029⟩. ⟨hal-04631262⟩

Marcin J Suskiewicz. The logic of protein post‐translational modifications (PTMs): Chemistry, mechanisms and evolution of protein regulation through covalent attachments. BioEssays, 2024, ⟨10.1002/bies.202300178⟩. ⟨hal-04438237⟩

Kang Zhu, Chatrin Chatrin, Marcin J Suskiewicz, Vincent Aucagne, Benjamin Foster, et al.. Ubiquitylation of nucleic acids by DELTEX ubiquitin E3 ligase DTX3L. EMBO Reports, 2024, 25 (10), pp.4172-4189. ⟨10.1038/s44319-024-00235-1⟩. ⟨hal-04739061⟩

Pietro Fontana, Sara C Buch-Larsen, Osamu Suyari, Rebecca Smith, Marcin J Suskiewicz, et al.. Serine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signalling. Nature Communications, 2023, 14 (1), pp.3200. ⟨10.1038/s41467-023-38793-y⟩. ⟨hal-04127612⟩

Marcin J Suskiewicz, Evgeniia Prokhorova, Johannes G M Rack, Ivan Ahel. ADP-ribosylation from molecular mechanisms to therapeutic implications. Cell, 2023, 186, pp.4475 - 4495. ⟨10.1016/j.cell.2023.08.030⟩. ⟨hal-04310798⟩

J Suskiewicz, Deeksha Munnur, Øyvind Strømland, Ji-Chun Yang, Laura E Easton, et al.. Updated protein domain annotation of the PARP protein family sheds new light on biological function. Nucleic Acids Research, 2023, ⟨10.1093/nar/gkad514/7199335⟩. ⟨hal-04131702⟩

Ostiane d'Augustin, Virginie Gaudon, Capucine Siberchicot, Rebecca Smith, Catherine Chapuis, et al.. Identification of key residues of the DNA glycosylase OGG1 controlling efficient DNA sampling and recruitment to oxidized bases in living cells. Nucleic Acids Research, 2023, 51 (10), pp.4942-4958. ⟨10.1093/nar/gkad243⟩. ⟨hal-04088267v2⟩

Xhaferr Tanushi, Guillaume Pinna, Marie Vandamme, Capucine Siberchicot, Ostiane D’augustin, et al.. OGG1 competitive inhibitors show important off-target effects by directly inhibiting efflux pumps and disturbing mitotic progression. Frontiers in Cell and Developmental Biology, 2023, 11, pp.1124960. ⟨10.3389/fcell.2023.1124960⟩. ⟨hal-04016264⟩

Stéphane Goffinont, Franck Coste, Pierre Prieu-Serandon, Lucija Mance, Virginie Gaudon, et al.. Structural insights into the regulation of the human E2∼SUMO conjugate through analysis of its stable mimetic. Journal of Biological Chemistry, In press, ⟨10.1016/j.jbc.2023.104870⟩. ⟨hal-04134078⟩

Kang Zhu, Marcin J Suskiewicz, Chatrin Chatrin, Øyvind Strømland, Bryan W Dorsey, et al.. DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on nucleic acids. Nucleic Acids Research, In press, ⟨10.1093/nar/gkad1119⟩. ⟨hal-04310807⟩

Coste Franck, Stéphane Goffinont, Julien Cros, Virginie Gaudon, Guérin Martine, et al.. Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Research, 2022, ⟨10.1093/nar/gkac932⟩. ⟨hal-03841526⟩

Kang Zhu, Marcin Suskiewicz, Andrea Hloušek-Kasun, Hervé Meudal, Andreja Mikoč, et al.. DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on protein substrates. Science Advances , 2022, 8 (40), ⟨10.1126/sciadv.add4253⟩. ⟨hal-03862525⟩

Kiyoto Kamagata, Nanako Iwaki, Saori Kanbayashi, Trishit Banerjee, Rika Chiba, et al.. Structure-dependent recruitment and diffusion of guest proteins in liquid droplets of FUS. Scientific Reports, 2022, 12 (1), pp.7101. ⟨10.1038/s41598-022-11177-w⟩. ⟨hal-03927893⟩

Jaromir Hunia, Karol Gawalski, Aleksandra Szredzka, Marcin J Suskiewicz, Dominika Nowis. The potential of PARP inhibitors in targeted cancer therapy and immunotherapy. Frontiers in Molecular Biosciences, 2022, 9, pp.1073797. ⟨10.3389/fmolb.2022.1073797⟩. ⟨hal-04127611⟩

Emmanuel Saridakis, Rishi Vishwakarma, Josephine Lai-Kee-Him, Kevin Martin, Isabelle Simon, et al.. Cryo-EM structure of transcription termination factor Rho from Mycobacterium tuberculosis reveals bicyclomycin resistance mechanism. Communications Biology, 2022, 5 (1), pp.120. ⟨10.1038/s42003-022-03069-6⟩. ⟨hal-03563179⟩

Kiyoto Kamagata, Nanako Iwaki, Milan Kumar Hazra, Saori Kanbayashi, Trishit Banerjee, et al.. Molecular principles of recruitment and dynamics of guest proteins in liquid droplets. Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-98955-0⟩. ⟨hal-03433608⟩

Franck Coste, Thierry Moreau, Valérie Labas, Magali Chessé, Mégane Brégeon, et al.. Three‐dimensional structures of avian beta‐microseminoproteins: insight from the chicken egg‐specific beta‐microseminoprotein 3 paralog. FEBS Open Bio, 2021, 11 (6), pp.1739-1756. ⟨10.1002/2211-5463.13166⟩. ⟨hal-03216446⟩