Post-doctoral position: Formulation and biological evaluation of magnetic nanovectors for improved combination therapy in Triple Negative Breast Cancer
Published on Feb. 6, 2026Contract: Temporary post-doctoral position starting as soon as possible (12 months)
Skill area: formulation and biological evaluation of nanovectors
Presentation of the research laboratory (UPR CNRS 4301 CBM – NMNS, Tours):
The research unit "Nanomedicines and Nanoprobes" is a department of the UPR CNRS 4301 Center for Molecular Biophysics and is situated at the faculty of pharmacy of the University of Tours. The research activity of this unit focuses on the development and the study of biocompatible nanosystems for therapeutic and/or diagnostic applications.
Missions:
The candidate will formulate superparamagnetic iron oxide nanoparticles (SPIONs) based nanovectors loaded with a chemotherapeutic drug and/or with small interfering RNA (siRNA). These nanovectors will then be evaluated in presence and absence of an external alternating magnetic field (AMF) on Triple Negative Breast Cancer (TNBC) cell or animal models. The candidate will be integrated in a collaborative project entitled “Magnetic control for improved combination therapy in Triple Negative Breast Cancer (MAGCOT)”, including three French teams and one Italian team, funded by the Institut National du Cancer (INCa, PLBIO22). The biological evaluation of the nanovectors will be done in collaboration with the two French teams. The candidate will be the link between the different teams.
Candidate profile:
The applicant should posses a solid experience (PhD) in formulation, characterization and biological evaluation of nanovectors. An expertise in SPIONs synthesis and biological evaluation in presence of an external alternating magnetic field will be a strong asset. Good scientific English as well as a significant experience in publishing are essential.
Contact and candidature:
Dr. Stephanie DAVID
Web-page of the laboratory NMNS : https://cbm.cnrs-orleans.fr/en/research/nmns/