Instrumentation

Confocal Raman/fluorescence microspectrometer
LabRAM (Jobin-Yvon Horiba)

• 491 nm
• 633 nm
• 691 nm
• 785 nm
• micromanipulated femto-injector
• thermostated micro-chamber

Confocal Raman/fluorescence microspectrometer
LabRam Soleil (Jobin-Yvon Horiba)

• 473 nm
• 532 nm
• 638 nm
• 691 nm
• 2 detectors
• dark field lighting

Confocal Raman/fluorescence microspectrometer
WiTec

• 532 nm
• 633 nm
• 785 nm

Raman skin composition analyser
RiverD gen2-SCA

• measurement window for in-vivo skin analysis
• 785 nm
• 830 nm

Industrial multichannel Raman monitor
Viserion (Indatech)

• 4 fiber optic Raman probes for simultaneous measurements
• 785 nm (3 independent channels)
• 830 nm (1 channel)

FTIR spectrophotometer
Frontier (Perkin Elmer)

• ATR accessory

Fluorescence spectrophotometer
FS5 (Edinburgh Instruments)

• thermostated cell
• integration sphere available

Fluorescence spectrophotometer
Cary Eclipse (Agilent)

• fiber optics accessory available

Capillary electrophoresis
P/ACE MDQ (Beckman Coulter)

• diode array detector
• laser induced fluorescence (488 nm)

Liquid Chromatography U-HPLC
Vanquish (Thermo Fisher Scientific)

• diode array detector
• high pressure gradient

Liquid Chromatography U-HPLC
Nexera (Shimadzu)

• diode array detector
• fluorescence detector
• low pressure gradient

Liquid Chromatography U-HPLC
1290 Infinity II Bio (Agilent)

• diode array detector
• high pressure gradient
• biocompatible

Dynamic light scattering (DLS) and zeta potential
Zetasizer Advance PRO (Malvern)

Rheometer Kinexus pro+ (Netzsch)

• type: rotational
• type of samples: fluids, semi-solids
• measures: viscosity, rheology, viscoelasticity
• torque range: 1.0 - 225 nN.m
• temperature range: 0 - 150 °C

Calorimetry for magnetic nanoparticles
MagneTherm (nanoTherics)
allows to study the impact of an alternative magnetic field on the heating capacity of nanovectors (NV) in real time

Options:

• Drug Release: study of the release of drugs that are loaded on the NV in suspension
• In vitro: study of the NV on cells
• In vivo: study of the NV on small animals (mice)

Photometric analyzer
Cedex Bio (Roche)

• glucose, glutamate, glutamine, lactate, LDH, IgG, total protein, ammonium, sodium, potassium

Biolayer interferometer Octet RED96e
(FortéBio)

Imaging system Fusion Solo S
(Vilber Lourmat)
for Western blot, DNA and RNA gels
(chemiluminescence, UV absorbance

Bioreactor for culture of animal cells
and controller Neptune (Pierre Guérin)

• total volume 4.6 L
• working volume 2.2 - 3.0 L
• pH, oxygen and optical density probes
• adapters for 2 Raman optical fiber probes
• adapter for a UV-vis probe

Microbiological safety cabinets, CO₂ incubators

• for pre-culture

Cryostat for tissue sectioning
CM3050 S (Leica)

• type of samples :
  skin (human, reconstructed, synthetic)
  other tissues
  cultured cells
• temperature range: -40 - 0 °C
• section thickness: 0.5 - 300 µm
• dimensions of samples: 40 x 55 mm

Ultrasound processor UP100H (Hielscher)
100 W, 30 kHz
volume 5 - 250 mL

• emulsification
• dispersion
• homogenization
• disagglomeration of nanomaterials
• degassing

Disperser ULTRA-TURRAX T 10 - IKA
speed 8000 - 30 000 rpm
volume 1 - 100 mL

• emulsification
• dispersion
• homogenization