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Krawczenko, A ; Kieda, C ; Dus, D

The biological role and potential therapeutic application of interleukin 7

Archivum Immunologiae et Therapiae Experimentalis 53 (6) 518-525

par Administrateur - publié le

Abstract :

Interleukin (lL)-7 is a pleiotropic, non-redundant cytokine necessary for the development of B and T lymphocytes, in particular ? d T cell receptor-positive cell differentiation. The cytokine can function as a cofactor during myelopoiesis and the generation of cytotoxic T cells and natural killer cells, can activate monocytes/macrophages, and support the survival of mature T cells.