Partenaires

CNRS


Rechercher


Accueil > Publications > Recherche par années > Années 2010 > 2012

Giuliani, A., Milosavljević, A. R., Hinsen, K., Canon, F., Nicolas, C., Réfrégiers, M. and Nahon, L.

Structure and Charge-State Dependence of the Gas-Phase Ionization Energy of Proteins

Angew Chem Int Ed Engl. 51 (38) 9552–9556

par Frapart - publié le , mis à jour le

Abstract :

Photoionization of protein ions : The ionization energy of polyprotonated protein cations in the gas phase measured using VUV synchrotron radiation appears to be correlated with the charge state z of the protein and its tertiary structure. A simple electrostatic model accounts for the results and also shows predictive capabilities to derive a mean radius R(m) of the protein ion from the ionization energy, and vice versa.