Organisation : Equipe Biologie cellulaire, Cibles moléculaires et Thérapies innovantes

GRILLON Catherine

email : catherine.grillon[remplacer_par_at]cnrs-orleans.fr

Téléphone : 02.38.25.78.04

Chargée de recherche, responsable de l’équipe “BCM : Biologie Cutanée et Microenvironnement”, responsable du département “BioBRAT”


141 documents

Article dans une revue51 documents

  • Nadira Chettouh-Hammas, Catherine Grillon. Physiological skin oxygen levels: An important criterion for skin cell functionality and therapeutic approaches. Free Radical Biology and Medicine, 2024, 222, pp.259-274. ⟨10.1016/j.freeradbiomed.2024.06.015⟩. ⟨hal-04627799⟩
  • Nadira Chettouh-Hammas, Fabienne Fasani, Amandine Boileau, David Gosset, Giovanni Busco, et al.. Improvement of Antioxidant Defences in Keratinocytes Grown in Physioxia: Comparison of 2D and 3D Models. Oxidative Medicine and Cellular Longevity, 2023, 2023, pp.1-15. ⟨10.1155/2023/6829931⟩. ⟨hal-04143382⟩
  • Bouchra El Hafny‐rahbi, Klaudia Brodaczewska, Guillaume Collet, Aleksandra Majewska, Krzysztof Klimkiewicz, et al.. Tumour angiogenesis normalized by myo‐inositol trispyrophosphate alleviates hypoxia in the microenvironment and promotes antitumor immune response. Journal of Cellular and Molecular Medicine, 2021, 25 (7), pp.3284-3299. ⟨10.1111/jcmm.16399⟩. ⟨hal-03391075⟩
  • Wissem Deraredj Nadim, Shalina Hassanaly, Hélène Bénédetti, Claudine Kieda, Catherine Grillon, et al.. The GTPase-activating protein-related domain of neurofibromin interacts with MC1R and regulates pigmentation-mediated signaling in human melanocytes. Biochemical and Biophysical Research Communications, 2021, 534, pp.758-764. ⟨10.1016/j.bbrc.2020.11.003⟩. ⟨hal-03007433⟩
  • Giovanni Busco, Robert Eric, Nadira Chettouh-Hammas, Jean-Michel Pouvesle, Catherine Grillon. The emerging potential of cold atmospheric plasma in skin biology. Free Radical Biology and Medicine, 2020, 161, pp.290-304. ⟨10.1016/j.freeradbiomed.2020.10.004⟩. ⟨hal-02967060⟩
  • Anthony Guillemain, Yousra Laouarem, Laetitia Cobret, Dora Štefok, Wanyin Chen, et al.. LINGO family receptors are differentially expressed in the mouse brain and form native multimeric complexes. FASEB Journal, 2020, pp.1-13. ⟨10.1096/fj.202000826R⟩. ⟨hal-02943248⟩
  • Anne-Claire Lagrée, Fabienne Fasani, Clotilde Rouxel, Marine Pivet, Marie Pourcelot, et al.. Bovine Organospecific Microvascular Endothelial Cell Lines as New and Relevant In Vitro Models to Study Viral Infections. International Journal of Molecular Sciences, 2020, ⟨10.3390/ijms21155249⟩. ⟨hal-03020363⟩
  • Olga Petrova, Isabelle Lamarre, Fabienne Fasani, Catherine Grillon, Michel Negrerie. Soluble Guanylate Cyclase Inhibitors Discovered among Natural Compounds. Journal of Natural Products, 2020, 83 (12), pp.3642-3651. ⟨10.1021/acs.jnatprod.0c00854⟩. ⟨hal-03335772⟩
  • Azadeh Valinataj Omran, Giovanni Busco, Loïck Ridou, Sébastien Dozias, Catherine Grillon, et al.. Cold atmospheric single plasma jet for RONS delivery on large biological surfaces. Plasma Sources Science and Technology, 2020, 29 (10), pp.105002. ⟨10.1088/1361-6595/abaffd⟩. ⟨hal-02967087⟩
  • Aneta Kantor, Agnieszka Krawczenko, Aleksandra Bielawska-Pohl, Danuta Duś, Catherine Grillon, et al.. Activity of the human immortalized endothelial progenitor cell line HEPC-CB.1 supporting in vitro angiogenesis.. Molecular Biology Reports, 2020, 47 (8), pp.5911-5925. ⟨10.1007/s11033-020-05662-6⟩. ⟨hal-03019876⟩
  • Xavier Janvier, Stephane Alexandre, Amine M Boukerb, Djouhar Souak, Olivier Maillot, et al.. Deleterious Effects of an Air Pollutant (NO2) on a Selection of Commensal Skin Bacterial Strains, Potential Contributor to Dysbiosis?. Frontiers in Microbiology, 2020, 11, ⟨10.3389/fmicb.2020.591839⟩. ⟨hal-03046433⟩
  • Adrien Blisnick, Ladislav Šimo, Catherine Grillon, Fabienne Fasani, Sébastien Brûlé, et al.. The Immunomodulatory Effect of IrSPI, a Tick Salivary Gland Serine Protease Inhibitor Involved in Ixodes ricinus Tick Feeding. Vaccines, 2019, 7 (4), pp.E148. ⟨10.3390/vaccines7040148⟩. ⟨hal-02354425⟩
  • Giovanni Busco, Azadeh Valinataj Omran, Loick Ridou, Jean-Michel Pouvesle, Eric Robert, et al.. Cold atmospheric plasma-induced acidification of tissue surface: visualization and quantification using agarose gel models. Journal of Physics D: Applied Physics, 2019, 52 (24), pp.24LT01. ⟨10.1088/1361-6463/ab1119⟩. ⟨hal-02089383⟩
  • Anna Dzimitrowicz, Aleksandra Bielawska-Pohl, Piotr Jamroz, Jerzy Dora, Agnieszka Krawczenko, et al.. Activation of the Normal Human Skin Cells by a Portable Dielectric Barrier Discharge-Based Reaction-Discharge System of a Defined Gas Temperature. Plasma Chemistry and Plasma Processing, 2019, ⟨10.1007/s11090-019-10039-0⟩. ⟨hal-02354478⟩
  • Dominika Wcisło-Dziadecka, Klaudia Simka, Agata Kaźmierczak, Celina Kruszniewska-Rajs, Joanna Gola, et al.. Psoriasis Treatment Changes the Expression Profile of Selected Caspases and their Regulatory MicroRNAs. Cellular Physiology and Biochemistry, 2018, 50 (2), pp.525 - 537. ⟨10.1159/000494166⟩. ⟨hal-01920480⟩
  • Catherine Grillon. Vers une peau rajeunie grâce au plasma froid ?. Microscoop. Hors-série, 2018, HS18. ⟨hal-03688676⟩
  • Giovanni Busco, Fabienne Fasani, Sébastien Dozias, Loick Ridou, Claire Douat, et al.. Changes in Oxygen Level Upon Cold Plasma Treatments: Consequences for RONS Production. IEEE Transactions on Radiation and Plasma Medical Sciences, 2018, 2 (2), pp.147 - 152. ⟨10.1109/TRPMS.2017.2775705⟩. ⟨hal-01803848⟩
  • Roya Mokhtar-Ahmadabadi, Zahra Madadi, Shiva Akbari-Birgani, Catherine Grillon, Leila Hasani, et al.. Developing a circularly permuted variant of Renilla luciferase as a bioluminescent sensor for measuring Caspase-9 activity in the cell-free and cell-based systems. Biochemical and Biophysical Research Communications, 2018, ⟨10.1016/j.bbrc.2018.11.009⟩. ⟨hal-01920476⟩
  • Krzysztof Klimkiewicz, Kazimierz Weglarczyk, Guillaume Collet, Maria Paprocka, Alan Guichard, et al.. A 3D model of tumour angiogenic microenvironment to monitor hypoxia effects on cell interactions and cancer stem cell selection. Cancer Letters, 2017, 396, pp.10 - 20. ⟨10.1016/j.canlet.2017.03.006⟩. ⟨hal-01618312⟩
  • Agnieszka Krawczenko, Aleksandra Bielawska-Pohl, Karolina Wojtowicz, Roksana Jura, Maria Paprocka, et al.. Expression and activity of multidrug resistance proteins in mature endothelial cells and their precursors: A challenging correlation. PLoS ONE, 2017, 12 (2), ⟨10.1371/journal.pone.0172371⟩. ⟨hal-01618329⟩
  • Nicolas Poupard, Pamela Badarou, Fabienne Fasani, Hugo Groult, Nicolas Bridiau, et al.. Assessment of Heparanase-Mediated Angiogenesis Using Microvascular Endothelial Cells: Identification of λ-Carrageenan Derivative as a Potent Anti Angiogenic Agent. Marine drugs, 2017, 15 (5), pp.284 - 298. ⟨10.3390/md15050134⟩. ⟨hal-01628620⟩
  • Anna Tejchman, Nathalie Lamerant-Fayel, Jean-Claude Jacquinet, Aleksandra Bielawska-Pohl, Katarzyna Mleczko-Sanecka, et al.. Tumor hypoxia modulates podoplanin/CCL21 interactions in CCR7+ NK cell recruitment and CCR7+ tumor cell mobilization. Oncotarget, 2017, 8, pp.31876-31887. ⟨10.18632/oncotarget.16311⟩. ⟨hal-01618778⟩
  • Guillaume Collet, Krzysztof Szade, Witold Nowak, Krzysztof Klimkiewicz, Bouchra El Hafny-Rahbi, et al.. Endothelial precursor cell-based therapy to target the pathologic angiogenesis and compensate tumor hypoxia. Cancer Letters, 2016, 370 (2), pp.345 - 357. ⟨10.1016/j.canlet.2015.11.008⟩. ⟨hal-01406899⟩
  • Mahdi Nadim, Shalina Hassanaly, Lydie Dubannet, Catherine Grillon. Physioxia and microRNAs as key factors in the skin microenvironment. IFSCC Magazine, 2015, 18 (1), pp.35-43. ⟨hal-01170034⟩
  • M Nadim, D Auriol, N Lamerant-Fayel, F Lefèvre, L Dubanet, et al.. Improvement of polyphenol properties upon glucosylation in a UV-induced skin cell ageing model.. International Journal of Cosmetic Science, 2014, 36 (6), pp.579-587. ⟨hal-01179536⟩
  • G. Collet, N. Lamerant-Fayel, M. Tertil, B. El Hafny-Rahbi, J. Stepniewski, et al.. Hypoxia-Regulated Overexpression of Soluble VEGFR2 Controls Angiogenesis and Inhibits Tumor Growth. Molecular Cancer Therapeutics, 2014, 13 (1), pp.165-178. ⟨10.1158/1535-7163.mct-13-0637⟩. ⟨hal-01178488⟩
  • Agata Matejuk, Guillaume Collet, Mahdi Nadim, Catherine Grillon, Claudine Kieda. MicroRNAs and Tumor Vasculature Normalization: Impact on Anti-Tumor Immune Response. Archivum Immunologiae et Therapiae Experimentalis, 2013, 61 (4), pp.285-299. ⟨10.1007/s00005-013-0231-4⟩. ⟨hal-00840182⟩
  • Claudine Kieda, Bouchra El Hafny-Rahbi, Guillaume Collet, Nathalie Lamerant-Fayel, Catherine Grillon, et al.. Stable tumor vessel normalization with pO2 increase and endothelial PTEN activation by inositol trispyrophosphate brings novel tumor treatment.. Journal of Molecular Medicine, 2013, epub ahead of print. ⟨10.1007/s00109-013-0992-6⟩. ⟨hal-00817464⟩
  • Guillaume Collet, Catherine Grillon, Mahdi Nadim, Kieda Claudine. Trojan horse at cellular level for tumor gene therapies.. Gene, 2013, 525 (2), pp.208-216. ⟨10.1016/j.gene.2013.03.057⟩. ⟨hal-00840161⟩
  • Catherine Grillon, Agata Matejuk, Mahdi Nadim, Nathalie Lamerant-Fayel, Claudine Kieda. News on microenvironmental physioxia to revisit skin cells targeting approaches.. Experimental Dermatology, 2012, 21 (10), pp.723-728. ⟨10.1111/j.1600-0625.2012.01551.x⟩. ⟨hal-00726575⟩
  • Guillaume Collet, Klaudia Skrzypek, Catherine Grillon, Agata Matejuk, Bouchra El Hafni-Rahbi, et al.. Hypoxia control to normalize pathologic angiogenesis: potential role for endothelial precursor cells and miRNAs regulation.. Vascular Pharmacology, 2012, 56 (5-6), pp.252-261. ⟨10.1016/j.vph.2012.03.001⟩. ⟨hal-00721811⟩
  • Aude Carreau, Catherine Grillon, Claudine Kieda. Nitric oxide modulates the expression of endothelial cell adhesion molecules involved in angiogenesis and leukocyte recruitment. Experimental Cell Research, 2011, 317 (1), pp.29-41. ⟨10.1016/j.yexcr.2010.08.011⟩. ⟨hal-00608218⟩
  • Aude Carreau, Bouchra El Hafny-Rahbi, Agata Matejuk, Catherine Grillon, Claudine Kieda. Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia. Journal of Cellular and Molecular Medicine, 2011, 15 (6), pp.1239-1253. ⟨10.1111/j.1582-4934.2011.01258.x⟩. ⟨hal-00608215⟩
  • Maria Paprocka, Agnieszka Krawczenko, Danuta Dus, Aneta Kantor, Aude Carreau, et al.. CD133 positive progenitor endothelial cell lines from human cord blood.. Cytometry Part A, 2011, 79 (8), pp.594-602. ⟨10.1002/cyto.a.21092⟩. ⟨hal-00720684⟩
  • Moez Berrich, Claudine Kieda, Catherine Grillon, Martine Monteil, Nathalie Lamerant, et al.. Differential Effects of Bartonella henselae on Human and Feline Macro- and Micro-Vascular Endothelial Cells. PLoS ONE, 2011, 6 (5), pp.Article Number: e20204. ⟨10.1371/journal.pone.0020204⟩. ⟨hal-00614878⟩
  • Maud Bréard, Catherine Grillon. Serotonin binds to purified neuronal nitric oxide synthase: a possible explanation for ROS production induced by 5HT in the presence of nNOS.. Free Radic Res, 2009, 43 (3), pp.206-13. ⟨10.1080/10715760802676662⟩. ⟨hal-00396425⟩
  • M. Breard, M. A. Sari, Y. Frapart, J. L. Boucher, C. Ducrocq, et al.. The endogenous neurotransmitter, serotonin, modifies neuronal nitric oxide synthase activities. Free Radical Research, 2007, 41 (4), pp.413-423. ⟨hal-00166640⟩
  • Fabienne Peyrot, Catherine Grillon, Catherine Vergely, Luc Rochette, Claire Ducrocq. Pharmacokinetics of 1-nitrosomelatonin and detection by EPR using iron dithiocarbamate complex in mice. Biochemical Journal, 2005, 387 (2), pp.473-478. ⟨10.1042/BJ20040828⟩. ⟨hal-02114605⟩
  • Josiane Thierry, Catherine Grillon, Sandrine Gaudron, Pierre Potier, Andrew Riches, et al.. Synthesis and biological evaluation of analogues of the tetrapeptideN-acetyl-Ser-Asp-Lys-Pro (AcSDKP), an inhibitor of primitive haematopoietic cell proliferation. Journal of Peptide Science, 2001, 7 (5), pp.284-293. ⟨10.1002/psc.322⟩. ⟨hal-02114610⟩
  • Sandrine Gaudron, Catherine Grillon, Josiane Thierry, Andrew Riches, Pieter Wierenga, et al.. In Vitro Effect of Acetyl‐N‐Ser‐Asp‐Lys‐Pro (AcSDKP) Analogs Resistant to Angiotensin I‐Converting Enzyme on Hematopoietic Stem Cell and Progenitor Cell Proliferation. STEM CELLS, 1999, 17 (2), pp.100-106. ⟨10.1002/stem.170100⟩. ⟨hal-02114616⟩
  • A. Massé, L. Ramirez, G Bindoula, Catherine Grillon, J. Wdzieczak-Bakala, et al.. The tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (Goralatide) protects from doxorubicin-induced toxicity: improvement in mice survival and protection of bone marrow stem cells and progenitors.. Blood, 1998, 91 (2), pp.441-9. ⟨hal-02114623⟩
  • N Cheviron, Catherine Grillon, M. Carlier, J. Wdzieczak-Bakala. The antiproliferative activity of the tetrapeptide Acetyl-N-SerAspLysPro, an inhibitor of haematopoietic stem cell proliferation, is not mediated by a thymosin beta 4-like effect on actin assembly.. Cell Proliferation, 1996, 29 (8), pp.437-46. ⟨hal-02114631⟩
  • Catherine Grillon, Dominique Bonnet, Jean‐Yves Mary, Maryse Lenfant, Albert Najman, et al.. The tetrapeptide acserasplyspro (seraspenide), a hematopoietic inhibitor, may reduce the in vitro toxicity of 3'-deoxythymidine to human hematopoietic progenitors. STEM CELLS, 1993, 11 (5), pp.455-464. ⟨10.1002/stem.5530110513⟩. ⟨hal-02114633⟩
  • J Wdzieczak-Bakala, Catherine Grillon, S Robinson, A Riches, P. Carde, et al.. Catabolism of the tetrapeptide N-Ac-Ser-Asp-Lys-Pro (AcSDKP), an inhibitor of hematopoietic stem cell (CFU-S) proliferation, following in vitro incubation with hematopoietic tissues from normal and leukemic mice.. Bulletin du Cancer, 1993, 80 (5), pp.391-6. ⟨hal-02114638⟩
  • C. Grillon, M Lenfant, J. Wdzieczak-Bakala. Optimization of cell culture conditions for the evaluation of the biological activities of the tetrapeptide N-Acetyl-Ser-Asp-Lys-Pro, a natural hemoregulatory factor.. Growth Factors, 1993, 9 (2), pp.133-8. ⟨hal-02114636⟩
  • M Lenfant, Catherine Grillon, J. Rieger, D Sotty, J. Wdzieczak-Bakala. Formation of acetyl-Ser-Asp-Lys-Pro, a new regulator of the hematopoietic system, through enzymatic processing of thymosin beta 4.. Annals of the New York Academy of Sciences, 1991, 628, pp.115-25. ⟨hal-02114977⟩
  • Catherine Grillon, M. Monsigny, C. Kieda. Soluble human lymphocyte sugar binding proteins with immunosuppressive activity.. Immunology Letters, 1991, 28 (1), pp.47-55. ⟨hal-02114973⟩
  • Catherine Grillon, M. Monsigny, C. Kieda. Changes in the expression of lectins in human T lymphocyte membrane upon mitogenic stimulation.. Carbohydrate Research, 1991, 213, pp.283-92. ⟨hal-02114648⟩
  • C Cerdan, Catherine Grillon, M. Monsigny, G Redziniak, C. Kieda. Human keratinocyte membrane lectins: characterization and modulation of their expression by cytokines.. Biology of the Cell, 1991, 73 (1), pp.35-42. ⟨hal-02114641⟩
  • Catherine Grillon, K Rieger, J. Bakala, D Schott, M Morgat, et al.. Involvement of thymosin beta 4 and endoproteinase Asp-N in the biosynthesis of the tetrapeptide AcSerAspLysPro a regulator of the hematopoietic system.. FEBS Letters, 1990, 274 (1-2), pp.30-4. ⟨hal-02114986⟩
  • Catherine Grillon, Michel Monsigny, Claudine Kieda. Cell surface lectins of human granulocytes: their expression is modulated by mononuclear cells and granulocyte/macrophage colony-stimulating factor. Glycobiology, 1990, 1 (1), pp.33-38. ⟨10.1093/glycob/1.1.33⟩. ⟨hal-02114980⟩

Communication dans un congrès47 documents

  • Catherine Grillon, Nadira Chettouh-Hammas, Loïck Ridou, Fabienne Fasani, Giovanni Busco. New reconstructed epidermis models closer to skin physiology. LeStudium conference: Skin Models in Cosmetic Science: Bridging Established Methods and Novel Technologies, 2nd meeting, Apr 2022, On line, France. ⟨hal-03838117⟩
  • Zeineb Maaroufi, Catherine Grillon. Mise en place d'outils pour étudier la fonction barrière de la peau pour évaluer l'effet du plasma froid. Journée ARD CVL Cosmétosciences, Nov 2022, Orléans, France. ⟨hal-04143455⟩
  • Zeineb Maaroufi, Augusto Stancampiano, Eric Robert, Catherine Grillon. Mise en place d’outils pour la caractérisation de la fonction barrière de la peau afin d’évaluer l’effet du plasma froid. 6ème colloque du GDR Cosm'actifs, Nov 2022, Reims, France. ⟨hal-04143480⟩
  • Nadira Chettouh-Hammas, Giovanni Busco, Fabienne Fasani, Catherine Grillon. Rôle du taux d’oxygénation sur l’activité antioxydante des cellules épidermiques. Congrès annuel de recherche en dermatologie (CARD), Jun 2022, Namur, Belgium. ⟨hal-03838130⟩
  • Nadira Chettouh-Hammas, Giovanni Busco, Fabienne Fasani, Catherine Grillon. Study of oxydative stress under the true oxygenation of the skin, physioxia. 12th International Conference on Skin Ageing and Challenges, Nov 2021, Lisbonne, Portugal. ⟨hal-03625163⟩
  • Nadira Chettouh-Hammas, Giovanni Busco, Fabienne Fasani, Catherine Grillon. Study of oxidative stress under the true oxygenation of the skin, Physioxia. 23rd International Conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants, Oct 2021, Virtual, France. ⟨hal-03394811⟩
  • Catherine Grillon. Organoïdes de peau pour des applications en biologie cutanée et cosmétique. 6e journée thématique Biotechnocentre « Cellules souches et Organoïdes: réalités et perspectives », Jun 2021, Virtual, France. ⟨hal-03394823⟩
  • Wanyin Chen, Anthony Guillemain, Lauren Blot, Fabienne Fasani, Esther Kellenberger, et al.. Anti-tumor activity of new ligands targeting LINGO1- a protein primarily expressed in CNS for the treatment of glioblastomas. Colloque Niche et épigénétique des tumeurs, Jul 2020, Online, France. ⟨hal-03686680⟩
  • Azadeh Valinataj Omran, Giovanni Busco, Loick Ridou, Sébastien Dozias, Catherine Grillon, et al.. Cold atmospheric single plasma jet for RONS delivery on large biological surfaces. 30th annual meeting of MRS-J (2020), International Symposium K Plasma Lifescience, Dec 2020, Virtual, France. ⟨hal-03394859⟩
  • Catherine Grillon. Les modèles cutanés. Atelier du GDR Cosmactifs « Microbiote et cosmétiques », Nov 2019, Evreux, France. ⟨hal-03025832⟩
  • Catherine Grillon, Nadira Chettouh-Hammas, Loïck Ridou, Shalina Hassanaly, Fabienne Fasani, et al.. Skin physioxia as a new parameter to improve in vitro skin models. Le Studium Conference: Skin Models in Cosmetic Science: Bridging Established Methods and Novel Technologies, Dec 2019, Tours, France. ⟨hal-03022530⟩
  • W. Chen, A. Guillemain, L. Blot, Fabienne Fasani, E. Kellenberger, et al.. The research of new therapeutic targets and small chemical molecules for glioblastoma therapies. Central South University in HuNan, Dec 2019, Changsha, China. ⟨hal-03686683⟩
  • Giovanni Busco, Azadeh Valinattaj Omran, Loick Ridou, Jean-Michel Pouvesle, Robert Eric, et al.. Plasmacosm2 : Le plasma froid, outil innovant pour la cosmétique.. Colloque Cosmétosciences, Feb 2019, Orléans, France. ⟨hal-03625180⟩
  • Azadeh Valinatajomran, Giovanni Busco, Loïck Ridou, Dozias Sébastien, Claire Douat, et al.. Cold Atmospheric Plasma for safe and tolerable tissue treatment. IMPCS1, Le Studium Loire Valley Institute for Advanced Studies • Région Centre-Val de Loire • FR, Nov 2019, Orléans, France. ⟨hal-03064683⟩
  • Azadeh Valinattaj Omran, Giovanni Busco, Sébastien Dozias, Catherine Grillon, Jean-Michel Pouvesle, et al.. Distribution and penetration of reactive oxygen and nitrogen species through a tissue phantom after plasma treatment.. Journée thématique des GDR B2I et Happybio, Oct 2019, Paris, France. ⟨hal-03022544⟩
  • Giovanni Busco, Azadeh Valinataj Omran, Loick Ridou, Jean-Michel Pouvesle, Robert Eric, et al.. A fluorescent method to measure plasma-induced surface acidification on tissue models. Journées Happybio 2019, Nov 2019, Nouan Le Fuzelier, France. ⟨hal-02463782⟩
  • Giovanni Busco, Azadeh Valinattaj Omran, Loick Ridou, Jean-Michel Pouvesle, Eric Robert, et al.. Le plasma froid, outil innovant pour la cosmétique, Plamsacosm-1 et -2. Séminaire Cosmétosciences, Nov 2018, Orléans, France. ⟨hal-03625188⟩
  • X. Janvier, D. Souak, O. Maillot, F. Gouriou, Catherine Grillon, et al.. Le dioxyde d’azote (NO2) atmospherique source d’altération du microbiote cutané ?. Réunion du GDR Cosmactifs, Sep 2018, Rennes, France. ⟨hal-03625194⟩
  • Xavier Janvier, Djouhar Souak, Fares Ousalem, Corinne Barbey, Magali Barreau, et al.. Effect of an atmospheric pollutant, NO2, on bacterial species of skin microbiota. 9th Int Conference on Skin Ageing and Challenges, Feb 2018, Porto, Portugal. ⟨hal-03625212⟩
  • Giovanni Busco, Loick Ridou, Fabienne Fasani, Sébastien Dozias, Jean-Michel Pouvesle, et al.. Investigation on a He-Plasma Gun source for cosmetic purposes:the importance of skin microenvironment. ICPM7, ISPM, Jun 2018, Philadelphia, United States. ⟨hal-01943058⟩
  • Catherine Grillon. Skin microenvironment in physiopathological conditions: role of microRNAs. LIA MiRTango meeting, Jun 2017, Cracovie, Poland. ⟨hal-03625256⟩
  • Catherine Grillon, E Robert, A Briolay. Le plasma froid, outil innovant pour la cosmétique : PLASMACOSM-2. Connexions R&D 2017, Nov 2017, Orléans, France. ⟨hal-03625224⟩
  • Catherine Grillon. Séminaire invité : La physioxie cutanée et ses conséquences. UDEAR, UMR 5165 CNRS, 1056 INSERM, Université de Toulouse (Séminaire, invitation du Dr Michel Simon), Jan 2017, Toulouse, France. ⟨hal-03625290⟩
  • Shalina Hassanaly, Alexia Perrin, Eric Mennesson, Isabelle Fixe, Nadia Normand, et al.. Modulation de la pigmentation de la peau par des phosphosaccharides : GLYCOSKIN-I, projet collaboratif en partenariat avec des industriels. Réunion du GDR Cosmactifs, Sep 2017, Nouan-le-Fuzelier, France. ⟨hal-03625219⟩
  • Catherine Grillon. La Physioxie cutanée. "Actualités en biologie cutanée",. 24e Cours de Biologie de la peau, CoBiP 2017, Mar 2017, Lyon, France. ⟨hal-03625284⟩
  • Claudine Kieda, Maciej Ugorski, Catherine Grillon, Anna Tejchman, Krzysztof Klimkiewicz. The role of glycosylation in hypoxia induced pathologic angiogenesis. Translational Glycobiology - 12th Jenner Glycobiologie and medicine Symposium, May 2017, Dubrovnic, Croatia. ⟨hal-03625265⟩
  • Catherine Grillon, Michel Musiol. How mutual knowledge can emerge from partial information : the monitoring of mutual understanding in dialogues between caregivers and severely disabled adolescents. International association for dialogue analysis (IADA) conference. Dialogue, interaction and culture : multidisciplinary perspectives on language use in everyday life, 2017, Bologna, Italy. ⟨hal-03188470⟩
  • Giovanni Busco, Fabienne Fasani, Sébastien Dozias, Loick Ridou, Claire Douat, et al.. Importance de la pression partielle d’oxygène lors des traitements par le plasma froid. Journées du GDR ABioPlas, GDR ABioPlas, Oct 2017, Paris, France. ⟨hal-01945949⟩
  • Catherine Grillon. Physioxie et vieillissement : état des lieux et connaissances. Réunion stratégique : Vieillissement cutané et innovations., Société française des antioxydants, Apr 2016, Paris, France. ⟨hal-03667963⟩
  • Claire Douat, Giovanni Busco, Vini Vijayarangan, Sebastien Dozias, Sylvain Iséni, et al.. Challenges in the transition from in vitro to in vivo experiments: source effects and biological aspects. IWPCT3, Apr 2016, Washington, United States. ⟨hal-01340223⟩
  • Giovanni Busco, Fabienne Fasani, Claire Douat, Sebastien Dozias, Jean-Michel M Pouvesle, et al.. Study of Chemico-Physical Properties of a He Plasma Gun in the Context of Skin Physioxia for Cosmetical Applications. 6th International Conference on Plasma Medicine (ICPM-6), Sep 2016, Bratislava, Slovakia. ⟨hal-01620850⟩
  • Catherine Grillon. Modèle cellulaire simple- Rôle de la physioxie. 1er atelier thématique du GDR Cosm’actifs Quel modèle pour tester l’activité d’un composé : de la molécule à l’homme, Mar 2016, Lyon, France. ⟨hal-03668565⟩
  • Shalina Hassanaly, Alexia Perrin, Fabienne Fasani, Claudine Kieda, Catherine Grillon. La physioxie : un paramètre essentiel dans la régulation de la mélanogénèse. 29e colloque Biotechnocentre, Oct 2016, Seillac, France. ⟨hal-03625251⟩
  • Anna Tejchman, Marek Chadalski, Catherine Grillon, Maciej Ugorski, Claudine Kieda. Effect of podoplanin expression in cancer associated fibroblasts (CAF) in breast cancer microenvironment and tumor progression. 3rd LIA MiRTango workshop “MicroRNAs: mediators of differentiation and biomarkers of diseases”, May 2016, Orléans, France. ⟨hal-03668570⟩
  • Catherine Grillon, Ilhan Said, Pauline Chopineau, Fabienne Fasani, Claudine Kieda, et al.. Glycosinolates et angiogenèse tumorale. Journée scientifique fédération de recherche FR2708, Jan 2016, Orléans, France. ⟨hal-03668560⟩
  • Eric Robert, Giovanni Busco, Catherine Grillon, Jean-Michel Pouvesle. Potential of low temperature atmospheric pressure plasma sources in cosmetic. COSMINNOV 2016, Cosmetic Valley, May 2016, Orléans, France. ⟨hal-01340267⟩
  • Krzysztof Klimkiewicz, Guillaume Collet, Catherine Grillon, Tadeusz Sarna, Claudine Kieda. 3-dimensional cell model of tumor microenvironment. 3rd LIA MiRTango workshop “MicroRNAs: mediators of differentiation and biomarkers of diseases”, May 2016, Orléans, France. ⟨hal-03668568⟩
  • Shalina Hassanaly, Alexia Perrin, Séverine Morisset-Lopez, Catherine Grillon. Modèles pour l’étude de la pigmentation. 1er atelier thématique du GDR Cosm’actifs Quel modèle pour tester l’activité d’un composé : de la molécule à l’homme, Mar 2016, Lyon, France. ⟨hal-03668561⟩
  • Giovanni Busco, Eric Robert, Jean-Michel Pouvesle, Catherine Grillon. Cosmetic application of a helium plasma gun. Séminaire ARD2020 Cosmetosciences, Apr 2016, Orléans, France. ⟨hal-03668559⟩
  • Jean-Michel Pouvesle, Thibault Darny, Sylvain Iséni, Xavier Damany, Giovanni Busco, et al.. Jets de plasmas atmosphériques pour des applications thérapeutiques de la décharge aux traitements: études, problèmes et enjeux. SFP PLASMA, SFP PLasma, Jun 2016, Nancy, France. ⟨hal-01340280⟩
  • Giovanni Busco, Fabienne Fasani, C. Douat, S. Dozias, Jean-Michel Pouvesle, et al.. Etude des propriétés du Plasma Froid à Hélium pour des Applications Cosmétiques. 1er colloque du GDR3711 Cosmactifs, Sep 2016, Moulin d’Andé, France. ⟨hal-03625242⟩
  • Catherine Grillon, Shalina Hassanaly, Alexia Perrin, Mahdi Nadim, Lydie Dubanet, et al.. Respecting physioxia is crucial in in vitro skin models: miRnome study in unstimulated skin cells and upon UV-induced photoaging. Cosminnov, May 2016, Orléans, France. ⟨hal-03668562⟩
  • Catherine Grillon. Quels modèles pour évaluer l’activité d’un composé? De la molécule au modèle humain. 1er colloque du GDR3711 Cosmactifs, Sep 2016, Moulin d'André, France. ⟨hal-03686188⟩
  • Marek Haftek, Claire Elfakir, Richard Daniellou, Chantal Larpent, Michel Grisel, et al.. Choice of models used for evaluation of biological activity of compounds: from in silicoto humans. COSMETOPEE 2016, Nov 2016, Tahiti, French Polynesia. ⟨hal-02565520⟩
  • Catherine Grillon. The key role of skin physioxia: microRNA expression in epidermal cells. 3rd LIA MiRTango workshop “MicroRNAs: mediators of differentiation and biomarkers of diseases”, May 2016, Orléans, France. ⟨hal-03668571⟩
  • M Berrich, Martine Monteil, C Kieda, C Grillon, J Gavard, et al.. Species-based endothelial cells reactivity to Bartonella infection and tumor angiogenesis.. 1st International Symposium on “Infection of Endothelium”, 2009, Dresden, Germany. pp.Inconnu. ⟨hal-02815532⟩
  • M Berrich, Martine Monteil, C Kieda, J Gavard, C Grillon, et al.. Effet pseudotumoral de Bartonella sur les cellules endothéliales humaines vs félines dérivées de la macro et la microcirculation. Journées d’Animation Scientifique du Département Santé Animale, 2009, Port d'Albret, France. pp.Inconnu. ⟨hal-02815359⟩

Poster38 documents

  • Nadira Chettouh-Hammas, Giovanni Busco, Fabienne Fasani, Catherine Grillon. Impact of oxygen level on epidermal cell antioxidant activity. Cosm’innov 5th edition, May 2023, Orléans, France. ⟨hal-04144932⟩
  • Nadira Chettouh-Hammas, Septuce Zin, Fabienne Fasani, Catherine Grillon. Novel reconstructed human epidermis model that restores skin physiological oxygen level. 33rd IFSCC Congress, Sep 2023, Barcelona, Spain. ⟨hal-04144944⟩
  • Zeineb Maaroufi, Augusto Stancampiano, Eric Robert, Catherine Grillon. Comparaison des effets de deux conditions de traitement par plasma froid sur les cellules de la peau. Journées GDR HappyBio, Nov 2022, Albi, France. ⟨hal-04143447⟩
  • David Gosset, Julien Sobilo, Herve Meudal, Frederic Szeremeta, Marylène Bertrand, et al.. Plateforme MO2VING: from MOlecular Organization to in Vivo ImagiNG. 34ème Colloque Biotechnocentre, Oct 2022, Nouan Le Fuzelier, France. ⟨hal-03863246⟩
  • Khadidja Sidelarbi, Fabienne Fasani, Séverine Morisset-Lopez, Catherine Grillon. Rôle différentiel de Lingo1 et Lingo3 dans la prolifération et la migration des cellules de glioblastome. 16èmes journées du Cancéropôle Grand Ouest, Jun 2021, Angers, France. ⟨hal-03838122⟩
  • Zeineb Maaroufi, Augusto Stancampiano, Eric Robert, Catherine Grillon. Etude des propriétés du PBS activé au plasma froid pour des applications cosmétiques. Colloque Conjoint GDR HappyBio-SFPb-SFPMed, Nov 2021, Toulouse, France. ⟨hal-03686218⟩
  • Wanyin Chen, Anthony Guillemain, Lauren Blot, Fabienne Fasani, Esther Kellenberger, et al.. Anti-tumor activity of new ligands targeting LINGO1- a protein primarily expressed in CNS for the treatment of glioblastomas. Colloque Niche et épigénétique des tumeurs, Jul 2020, Online, France. . ⟨hal-03686675⟩
  • Giovanni Busco, Fabienne Fasani, Sébastien Dozias, Claire Douat, Eric Robert, et al.. Le plasma froid comme nouvel outil au service de la cosmétique, Plasmacosm-1. Colloque Cosmétosciences, Feb 2019, Orléans, France. ⟨hal-03668573⟩
  • Giovanni Busco, Azadeh Valinataj Omran, Loick Ridou, Jean-Michel Pouvesle, Eric Robert, et al.. Fluorescein-agarose gel as a tissue model to visualize and measure local CAP-induced acidification. 24th International Symposium on Plasma Chemistry (ISPC24), Jun 2019, Naples, Italy. ⟨hal-02263357⟩
  • Wanyin Chen, Anthony Guillemain, Lauren Blot, Fabienne Fasani, Esther Kellenberger, et al.. Etude de l’activité anti-tumorale de nouveaux ligands ciblant LINGO-1 pour le traitement des glioblastomes. Colloque de l’ADOC, Jul 2019, Orléans, France. ⟨hal-03686230⟩
  • Azadeh Valinataj Omran, Giovanni Busco, Sébastien Dozias, C. Grillon, Jean-Michel Pouvesle, et al.. Distribution and penetration of reactive oxygen and nitrogen species through a tissue phantom after Plasma Gun treatment. 24th International Symposium on Plasma Chemistry (ISPC24),, Jun 2019, Naples, Italy. ⟨hal-02263879⟩
  • W. Chen, A. Guillemain, L. Blot, F. Fasani, E. Kellenberger, et al.. Nouvelles molécules chimiques anti-tumorales pour le traitement du glioblastomes. 13es journées du Cancéropôle Grand Ouest, Jul 2019, Tours, France. ⟨hal-02973622⟩
  • Nadira Chettouh-Hammas, Giovanni Busco, Fabienne Fasani, Catherine Grillon. Study of oxidative stress under the true oxygenation of the skin, physioxia. SFC international Symposium, Journées Jean-Paul Marty « peau & âge », Dec 2019, Paris, France. ⟨hal-03022523⟩
  • Wanyin Chen, Anthony Guillemain, Laurent Blot, Fabienne Fasani, E. Kellenberger, et al.. Anti-tumoral activity of new ligands targeting LINGO-1 for the treatment of glioblastoma. 1st meeting « Niches and Epigenetic of tumors », Mar 2019, Nantes, France. ⟨hal-02973567⟩
  • Giovanni Busco, Azadeh Valinataj Omran, Loïck Ridou, Jean-Michel Pouvesle, Eric Robert, et al.. Fluorescein-agarose gel as a tissue model to visualize and measure local CAP-induced acidification. Journée Fédération FR2708 Physique et Chimie du Vivant, Apr 2019, Orléans, France. ⟨hal-03625299⟩
  • Nadira Chettouh-Hammas, Giovanni Busco, Fabienne Fasani, Catherine Grillon. Etude du stress oxydant dans les conditions réelles d'oxygénation de la peau : la physioxie.. 32e Colloque Biotechnocentre, Oct 2019, Seillac, France. ⟨hal-03022548⟩
  • Wanyin Chen, Anthony Guillemain, Lauren Blot, Fabienne Fasani, Esther Kellenberger, et al.. Etude de l’activité anti-tumorale de nouveaux ligands ciblant LINGO-1 pour le traitement des glioblastomes. Journée Fédération FR2708 Physique et Chimie du Vivant, Apr 2019, Orléans, France. ⟨hal-03625295⟩
  • Giovanni Busco, Azadeh Valinattaj Omran, Loïck Ridou, Fabienne Fasani, Sébastien Dozias, et al.. Le plasma froid, outil innovant pour la cosmétique, Plasmacosm-2. Colloque Cosmétosciences, Feb 2019, Orléans, France. ⟨hal-03625347⟩
  • L. Blot, Y. Makhloufi, V. Sarou-Kainian, A. Guillemain, C. Grillon, et al.. Développement des gliomes chez Drosophila Melanogaster: rôle du récepteur 5-HT7 de la sérotonine. Journée Scientifique de la fédération de Recherche FR 2708, Jan 2018, Orléans, France. ⟨hal-02973683⟩
  • Shalina Hassanaly, Nadia Normand, Ludovic Landemarre, Elian Lati, Jean- Christophe Choulot, et al.. Melanosome transfer to keratinocytes as a valuable target to control skin pigmentation: role of 6-phosphogalactose. 30th IFSCC Congress 2018, Sep 2018, Munich, Germany. ⟨hal-03625376⟩
  • Séverine Morisset-Lopez, L. Blot, A. Guillemain, C. Grillon, D. Decoville. Identification of new partner of EGF receptor: functional interaction and interest for the treatment of glioma. Studium conference Stem cells and cancer stem cells, Jun 2018, Orléans, France. ⟨hal-02973700⟩
  • Jolanta Hybiak, Marine Pivet, Fabienne Fasani, Andrzej Hudecki, Catherine Grillon, et al.. Selected biodegradable and nonbiodegradable materials - their impact on cells growth and proliferation. Le Studium Conférence "Stem cells and cancer stem cells : regenerative medicine and cancer", Jun 2018, Orléans, France. ⟨hal-03625371⟩
  • Giovanni Busco, Fabienne Fasani, Sébastien Dozias, Loick Ridou, Claire Douat, et al.. Changes in oxygen level upon cold plasma treatments: consequences for RONS production. Journée Fédération FR2708 Physique et Chimie du Vivant, Jan 2018, Orléans, France. ⟨hal-03625366⟩
  • Marine Pivet, Fabienne Fasani, Claudine Kieda, Catherine Grillon. Une nouvelle stratégie pour stabiliser la normalisation de l’angiogenèse tumorale afin d’améliorer l’efficacité des traitements anti-cancéreux. 12es Journées du Canceropôle Grand Ouest, Jul 2018, Vannes, France. ⟨hal-03686242⟩
  • Marine Pivet, Fabienne Fasani, Eric Mennesson, Artur Cieslar, Marek Los, et al.. Une nouvelle stratégie pour stabiliser la normalisation de l’angiogenèse tumorale afin d’améliorer l’efficacité des traitements anti-cancéreux. Le Studium Conférence « Stem cells and cancer stem cells : regenerative medicine and cancer », Jun 2018, Orléans, France. ⟨hal-03668574⟩
  • Marine Pivet, Fabienne Fasani, Eric Mennesson, Artur Cieslar, Marek Los, et al.. Une nouvelle stratégie pour stabiliser la normalisation de l’angiogenèse tumorale afin d’améliorer l’efficacité des traitements anti-cancéreux. 5th LIA MiRTANGO worshop, May 2018, Orléans, France. ⟨hal-03625369⟩
  • L. Blot, A. Guillemain, C. Grillon, D. Decoville, Séverine Morisset-Lopez. Identification d’un nouveau partenaire de l’EGFR : interaction fonctionnelle et intérêt pour le traitement des tumeurs cérébrales. 12es journées du cancéropôle Grand Ouest, Jul 2018, Vannes, France. ⟨hal-02973707⟩
  • Giovanni Busco, Claire Douat, Fabienne Fasani, Sébastien Dozias, Jean-Michel Pouvesle, et al.. Changes in oxygen level upon plasma treatments : consequences for RONS production?. 4th International Workshop on Plasma for CancerTreatment (IWPCT–2017), Mar 2017, Paris, France. . ⟨hal-02453420⟩
  • Anna Tejchman, Eric Mennesson, Isabelle Fixe, Alexandra Foucher, Simón Perera, et al.. Bioinformatics miRNome analyses reveal that activity of CAF expressed podoplanin in tumor microenvironment is modulated by exosome miRNAs involved in the PTEN/PI3K/AKT/mTOR signaling. AACR Annual Meeting 2017, Apr 2017, Washington, United States. ⟨hal-02453415⟩
  • Xavier Janvier, D. Souak, F. Gouriou, Catherine Grillon, M. G. J. Feuilloley, et al.. Effet d’un polluant atmosphérique, le NO2, sur une bactérie du microbiote cutané : Staphylococcus epidermidis MFP04. Réunion du GDR Cosmactifs, Sep 2017, Nouan-le-Fuzelier, France. ⟨hal-03625363⟩
  • L. Blot, Y. Makhloufi, A. Guillemain, C. Grillon, Séverine Morisset-Lopez, et al.. Rôle du récepteur 5-HT7 de la sérotonine dans le développement des gliomes chez Drosophila Melanogaster. 11es journées du Cancéropôle Grand Ouest, Jun 2017, Vannes, France. ⟨hal-02973773⟩
  • Giovanni Busco, Fabienne Fasani, Claire Douat, Sébastien Dozias, Jean-Michel Pouvesle, et al.. Study of Chemico-Physical Properties of a He Plasma Gun in the Context of Skin Physioxia for Cosmetical Applications. Journées du GDR ABioPlas, Nov 2016, Albi, France. ⟨hal-01945786⟩
  • Martine Decoville, Anthony Guillemain, Catherine Grillon, Séverine Morisset. Effect of the serotonin 5-HT7 recepteur on cellular proliferation in Drosophila melanogaster. 5th annual meeting of the GDR 3545 RCPG-PhysioMed 2016, Nov 2016, Tours, France. ⟨hal-02453412⟩
  • Shalina Hassanaly, Wissem Deraredj Nadim, Claudine Kieda, Séverine Morisset, Catherine Grillon. Regulation of MC1R-mediated pigmentation by the GRD domain of neurofibromin in human melanocytes. 20th ESPCR Meeting, Sep 2016, Milan, Italy. ⟨hal-02453404⟩
  • Anna Tejchman, Marek Chadalski, Catherine Grillon, Claudine Kieda, Maciej Ugorski. Effect of podoplanin expression in cancer associated fibroblasts (CAF) in breast cancer microenvironment and tumor progression. 10es Journées du Cancéropôle Grand Ouest, Jun 2016, Les Sables-d'Olonne, France. ⟨hal-02453399⟩
  • Nicolas Poupard, Pamela Badarou, Hugo Groult, Nicolas Bridiau, Claudine Kieda, et al.. Élaboration d’un modèle basé sur des cellules endothéliales microvasculaires pour étudier l’impact de l’héparanase dans l’angiogenèse tumorale. 10èmes Journées du Cancéropôle Grand Ouest, Jun 2016, Les Sables d'Olonne, France. . ⟨hal-02453398⟩
  • Shalina Hassanaly, Wissem Deraredj Nadim, Claudine Kieda, Séverine Morisset, Catherine Grillon. Regulation of MC1R-mediated pigmentation in human melanocytes by the GRD domain of neurofibromin. 5th annual meeting of the GDR 3545 RCPG-PhysioMed 2016, Nov 2016, Tours, France. ⟨hal-02453410⟩
  • M Berrich, C Kieda, C Grillon, Martine Monteil, J Gavard, et al.. In vitro effects of Bartonella henselae on human and feline endothelial cells.. 6th International Conference on Bartonella as Medical and Veterinary Pathogens, 2009, Chester, United Kingdom. pp.Inconnu, 2009. ⟨hal-02815323⟩

Ouvrage (y compris édition critique et traduction)1 document

  • Catherine Grillon, Marek Haftek. Modèles pour l'évaluation des produits cosmétiques : de la molécule à l'homme. 2018. ⟨hal-02115727⟩

Chapitre d'ouvrage3 documents

  • Marek Łos, Soumya Panigrahi, Katarzyna Sielatycka, Catherine Grillon. Successful Biomaterial-Based Artificial Organ—Updates on Artificial Blood Vessels. Łos M. J., Hudecki A., Wiecheć E. Stem Cells and Biomaterials for Regenerative Medicine, Elsevier, pp.203-222, 2019. ⟨hal-02114999⟩
  • Catherine Grillon. Les modèles cellulaires simples. Grillon C., Haftek M.,. Modèles pour l'évaluation des produits cosmétiques : de la molécule à l'homme, Cosmetic Valley Editions, pp.35-48, 2018. ⟨hal-02115730⟩
  • Maria Paprocka, Catherine Grillon, Danuta Duś, Claudine Kieda. Endothelium in Pathologic Angiogenesis and Angiogenesis-Mediated Therapies. Angiogenesis and vascularisation: Cellular and molecular mechanisms in health and diseases, Springer Vienna, pp.389-406, 2013, ⟨10.1007/978-3-7091-1428-5_18⟩. ⟨hal-02070898⟩

Brevet1 document

  • Catherine Grillon, Kieda Claudine, Fabienne Fasani, Nadia Haddad, Boullouis Henri-Jean, et al.. Cellule endothéliale organospécifique isolée d’origine bovine ou canine et ses utilisations. France, Patent n° : FR1915307. BIOBRAT. 2020. ⟨hal-03021836⟩

Documents récupérés de l'archive ouverte HAL logo

 

GODIN Fabienne

email : fabienne.godin[remplacer_par_at]cnrs-orleans.fr

Téléphone : 02.38.25.76.05

Ingénieure en techniques biologiques au sein du groupe thématique “Signalisation cellulaire et neurofibromatose”

 


0 documents

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BÉNÉDETTI Hélène

mail : helene.benedetti[remplacer_par_at]cnrs-orleans.fr

Téléphone : 02.38.25.55.84

Directrice de recherche, Directrice adjointe du CBM, co-coordinatrice du département “Signalisation cellulaire, cibles moléculaires et thérapies innovantes” et co-responsable de l’équipe “Signalisation cellulaire et neurofibromatose”


126 documents

Article dans une revue67 documents

  • Mohammed Bergoug, Christine Mosrin-Huaman, Amandine Serrano, Fabienne Godin, Michel Doudeau, et al.. An Atypical Mechanism of SUMOylation of Neurofibromin SecPH Domain Provides New Insights into SUMOylation Site Selection. Journal of Molecular Biology, 2024, 436 (22), pp.168768. ⟨10.1016/j.jmb.2024.168768⟩. ⟨hal-04771131⟩
  • Anthony Champiré, Rayan Berabez, Abdennour Braka, Aurélie Cosson, Justine Corret, et al.. Tetrahydropyridine LIMK inhibitors: Structure activity studies and biological characterization. European Journal of Medicinal Chemistry, 2024, 271, pp.116391-116391. ⟨10.1016/j.ejmech.2024.116391⟩. ⟨hal-04575964⟩
  • Hélène Bénédetti, Béatrice Vallée. LIM Kinases: From Molecular to Pathological Features. Cells, 2023, 12 (12), pp.1649. ⟨10.3390/cells12121649⟩. ⟨hal-04208415⟩
  • Elodie Villalonga, Christine Mosrin, Thierry Normand, Caroline Girardin, Amandine Serrano, et al.. LIM Kinases, LIMK1 and LIMK2, Are Crucial Node Actors of the Cell Fate: Molecular to Pathological Features. Cells, 2023, 12 (5), pp.805. ⟨10.3390/cells12050805⟩. ⟨hal-04208405⟩
  • Rayan Berabez, Sylvain Routier, Hélène Bénédetti, Karen Plé, Béatrice Vallée. LIM kinases, promising but reluctant therapeutic targets: chemistry and preclinical validation in vivo. Cells, 2022, 11 (13), pp.2090. ⟨10.3390/cells11132090⟩. ⟨hal-03721458⟩
  • Bojan Žunar, Christine Mosrin-Huaman, Hélène Bénédetti, Béatrice Vallée. Re-engineering of CUP1 promoter and Cup2/Ace1 transactivator to convert Saccharomyces cerevisiae into a whole-cell eukaryotic biosensor capable of detecting 10 nM of bioavailable copper. Biosensors and Bioelectronics, 2022, 214, pp.114502. ⟨10.1016/j.bios.2022.114502⟩. ⟨hal-03820214⟩
  • Wissem Deraredj Nadim, Shalina Hassanaly, Hélène Bénédetti, Claudine Kieda, Catherine Grillon, et al.. The GTPase-activating protein-related domain of neurofibromin interacts with MC1R and regulates pigmentation-mediated signaling in human melanocytes. Biochemical and Biophysical Research Communications, 2021, 534, pp.758-764. ⟨10.1016/j.bbrc.2020.11.003⟩. ⟨hal-03007433⟩
  • Skander A Abboud, Hadji H., Michel Doudeau, Hélène Bénédetti, Vincent Aucagne. A straightforward methodology to overcome solubility challenges for N-terminal cysteinyl peptide segments used in native chemical ligation. Chemical Science, 2021, 12, pp.3194 - 3201. ⟨10.1039/d0sc06001a⟩. ⟨hal-03447239⟩
  • Frédéric Buron, Nuno Rodrigues, Thibault Saurat, Marie-Aude Hiebel, Stéphane Bourg, et al.. Design, Synthesis and SAR in 2,4,7-Trisubstituted Pyrido[3,2-d]Pyrimidine Series as Novel PI3K/mTOR Inhibitors. Molecules, 2021, 26 (17), pp.5349. ⟨10.3390/molecules26175349⟩. ⟨hal-03348966⟩
  • Mohammed Bergoug, Michel Doudeau, Fabienne Godin, Christine Mosrin-Huaman, Béatrice Vallée, et al.. Neurofibromin Structure, Functions and Regulation. Cells, 2020, 9, ⟨10.3390/cells9112365⟩. ⟨hal-03070759v2⟩
  • Béatrice Vallée, Michel Doudeau, Fabienne Godin, Hélène Bénédetti. Characterization at the Molecular Level using Robust Biochemical Approaches of a New Kinase Protein. Journal of visualized experiments : JoVE, 2019, 148, pp.e59820. ⟨10.3791/59820⟩. ⟨hal-02282630⟩
  • Julie Tastet, Hélène Cuberos, Béatrice Vallée, Annick Toutain, Martine Raynaud, et al.. LIMK2-1 is a Hominidae-Specific Isoform of LIMK2 Expressed in Central Nervous System and Associated with Intellectual Disability. Neuroscience, 2019, 399, pp.199-210. ⟨10.1016/j.neuroscience.2018.12.017⟩. ⟨hal-02067472⟩
  • Béatrice Vallée, Hélène Cuberos, Michel Doudeau, Fabienne Godin, David Gosset, et al.. LIMK2-1, a new isoform of human LIMK2, regulates actin cytoskeleton remodeling via a different signaling pathway than that of its two homologs, LIMK2a and LIMK2b. Biochemical Journal, 2018, 475 (23), pp.3745-3761. ⟨hal-01966439⟩
  • Viorel Simion, Wissem Deraredj Nadim, Hélène Bénédetti, Chantal Pichon, Séverine Morisset-Lopez, et al.. Pharmacomodulation of microRNA Expression in Neurocognitive Diseases: Obstacles and Future Opportunities. Current Neuropharmacology, 2017, 15 (2), pp.276 - 290. ⟨10.2174/1570159X14666160630210422⟩. ⟨hal-01618771⟩
  • Wissem Deraredj Nadim, Simion Viorel, Hélène Bénédetti, Chantal Pichon, Patrick Baril, et al.. MicroRNAs in Neurocognitive Dysfunctions: New Molecular Targets for Pharmacological Treatments?. Current Neuropharmacology, 2017, 15 (2), pp.260 - 275. ⟨10.2174/1570159X14666160709001441⟩. ⟨hal-01618199⟩
  • Wissem Deraredj Nadim, Séverine Chaumont-Dubel, Fahima Madouri, Laetitia Cobret, Marie-Ludivine de Tauzia, et al.. Physical interaction between neurofibromin and serotonin 5-HT 6 receptor promotes receptor constitutive activity. Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (43), pp.12310 - 12315. ⟨10.1073/pnas.1600914113⟩. ⟨hal-01407899⟩
  • L Cobret, M L de Tauzia, J Ferent, E Traiffort, I Hénaoui, et al.. Targeting the cis-dimerization of LINGO-1 with low MW compounds affects its downstream signalling. British Journal of Clinical Pharmacology, 2015, 172 (3), pp.841-856. ⟨10.1111/bph.12945⟩. ⟨hal-01170735⟩
  • Julie Tastet, Loïc Decalonne, Sylviane Marouillat, Joëlle Malvy, Rose-Anne Thépault, et al.. Mutation screening of the ubiquitin ligase gene RNF135 in French patients with autism. Psychiatric Genetics, 2015, 25 (6), pp.263-267. ⟨10.1097/ypg.0000000000000100⟩. ⟨hal-02072312⟩
  • H. Cuberos, B. Vallée, P. Vourc'H, J. Tastet, C.R. Andres, et al.. Roles of LIM kinases in central nervous system function and dysfunction. FEBS Letters, 2015, 589 (24PartB), pp.3795-3806. ⟨10.1016/j.febslet.2015.10.032⟩. ⟨hal-02072231⟩
  • Reine Nehmé, Hala Nehmé, Thibault Saurat, Marie-Ludivine De-Tauzia, Frédéric Buron, et al.. New in-capillary electrophoretic kinase assays to evaluate inhibitors of the PI3k/Akt/mTOR signaling pathway. Analytical and Bioanalytical Chemistry, 2014, 406 (15), pp.3743-3754. ⟨10.1007/s00216-014-7790-z⟩. ⟨hal-01180770⟩
  • Amélie Bruel, Romain Beneteau, Mylène Chabanne, Olivier Lozach, Rémy Le Guevel, et al.. Synthesis of new pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs as DYRK1A inhibitors. Bioorganic and Medicinal Chemistry Letters, 2014, 24 (21), pp.5037 - 5040. ⟨10.1016/j.bmcl.2014.09.017⟩. ⟨hal-01086026⟩
  • Solene Guiheneuf, Ludovic Paquin, Francois Carreaux, Emilie Durieu, Helene Benedetti, et al.. Microwave Assisted Organic Synthesis (MAOS) of New Dispacamide A Derivatives Bearing a Thiazolinone Platform, Biological Assays on Inhibition of Protein Kinases and Cell Effects. Current microwave chemistry, 2014, 1 (1), pp.33-40. ⟨10.2174/22133356114019990002⟩. ⟨hal-01114583⟩
  • Thibault Saurat, Frédéric Buron, Nuno Rodrigues, Marie-Ludivine de Tauzia, Lionel Colliandre, et al.. Design, Synthesis, and Biological Activity of Pyridopyrimidine Scaffolds as Novel PI3K/mTOR Dual Inhibitors. Journal of Medicinal Chemistry, 2014, 57 (3), pp.613-631. ⟨10.1021/jm401138v⟩. ⟨hal-01180887⟩
  • François Hericourt, François Chefdor, Lucie Bertheau, Mirai Tanigawa, Tatsuya Maeda, et al.. Characterization of histidine-aspartate kinase HK1 and identification of histidine phosphotransfer proteins as potential partners in a Populus multistep phosphorelay. Physiologia Plantarum, 2013, 149 (2), pp.188-199. ⟨10.1111/ppl.12024⟩. ⟨hal-02070851⟩
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  • Béatrice Vallée, Michel Doudeau, Fabienne Godin, Aurélie Gombault, Aurélie Tchalikian-Cosson, et al.. Nf1 RasGAP Inhibition of LIMK2 Mediates a New Cross-Talk between Ras and Rho Pathways. PLoS ONE, 2012, 7 (10), pp.e47283. ⟨10.1371/journal.pone.0047283⟩. ⟨hal-03054185⟩
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  • Julie Tastet, Patrick Vourc'H, Frédéric Laumonnier, Béatrice Vallée, Carole Michelle, et al.. LIMK2d, a truncated isoform of Lim kinase 2 regulates neurite growth in absence of the LIM kinase domain. Biochemical and Biophysical Research Communications, 2012, 420 (2), pp.247-252. ⟨10.1016/j.bbrc.2012.02.134⟩. ⟨hal-01136281⟩
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  • S. Castella, Hélène Bénédetti, R. de Llorens, J.L. Dacheux, F. Dacheux. Train A, an RNase-A-like protein without RNase activity is secreted and reabsorbed by the same epididymal cells under testicular control. Biology of Reproduction, 2004, 71 (5), pp.1677-1687. ⟨10.1095/biolreprod.104.031666⟩. ⟨hal-00112960⟩
  • H. Chautard, M. Jacquer, F. Schoentgen, N. Bureaud, H. Bénédetti. Tfs1, a member of the PEBP family, inhibits the Ira2p but not the Ira1p Ras GTPase activating protein in Saccharomyces cerevisiae. Eukaryotic Cell, 2004, 3 (2), pp.459-470. ⟨10.1128/EC.3.2.459-470.2004⟩. ⟨hal-00112967⟩
  • Emmanuelle Bouveret, Laure Journet, Anne Walburger, E. Cascales, Hélène Bénédetti, et al.. Analysis of the Escherichia coli Tol-Pal and TonB systems by periplasmic production of Tol, TonB, colicin, or phage capsid soluble domains.. Biochimie, 2002, 84 (5-6), pp.413-21. ⟨hal-02130103⟩
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  • C. Lazdunski, E. Bouveret, A Rigal, Laure Journet, R. Lloubes, et al.. Colicin import into Escherichia coli cells requires the proximity of the inner and outer membranes and other factors. International Journal of Medical Microbiology, 2000, 290 (4-5), pp.337-344. ⟨10.1016/S1438-4221(00)80037-5⟩. ⟨hal-02130686⟩
  • Chantal Abergel, E. Bouveret, J.M Claverie, K Brown, A Rigal, et al.. Structure of the Escherichia coli TolB protein determined by MAD methods at 1.95 A resolution.. Structure, 1999, 7 (10), pp.1291-300. ⟨hal-02130130⟩
  • E Bouveret, H Bénédetti, A Rigal, E. Loret, C Lazdunski. In vitro characterization of peptidoglycan-associated lipoprotein (PAL)-peptidoglycan and PAL-TolB interactions.. Journal of Bacteriology, 1999, 181 (20), pp.6306-11. ⟨hal-02130134⟩
  • Laure Journet, A Rigal, C Lazdunski, H Bénédetti. Role of TolR N-terminal, central, and C-terminal domains in dimerization and interaction with TolA and tolQ.. Journal of Bacteriology, 1999, 181 (15), pp.4476-84. ⟨hal-02130149⟩
  • Chantal Abergel, A Rigal, S Chenivesse, C Lazdunski, J.M Claverie, et al.. Crystallization and preliminary crystallographic study of a component of the Escherichia coli tol system: TolB.. Acta crystallographica Section D : Structural biology [1993-..], 1998, 54 (Pt 1), pp.102-4. ⟨hal-02130160⟩
  • C.J Lazdunski, E. Bouveret, A. Rigal, Laure Journet, R Lloubès, et al.. Colicin import into Escherichia coli cells.. Journal of Bacteriology, 1998, 180 (19), pp.4993-5002. ⟨hal-02130152⟩
  • E Bouveret, A Rigal, C Lazdunski, H Bénédetti. Distinct regions of the colicin A translocation domain are involved in the interaction with TolA and TolB proteins upon import into Escherichia coli.. Molecular Microbiology, 1998, 27 (1), pp.143-57. ⟨hal-02130155⟩
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  • R Derouiche, H Bénédetti, Jc Lazzaroni, C Lazdunski, R Lloubès. Protein complex within Escherichia coli inner membrane. TolA N-terminal domain interacts with TolQ and TolR proteins. Journal of Biological Chemistry, 1995, 270 (19), pp.11078-11084. ⟨10.1074/jbc.270.19.11078⟩. ⟨hal-02130187⟩
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  • G. Guihard, P. Boulanger, H Bénédetti, R Lloubés, M Besnard, et al.. Colicin A and the Tol proteins involved in its translocation are preferentially located in the contact sites between the inner and outer membranes of Escherichia coli cells.. Journal of Biological Chemistry, 1994, 269 (8), pp.5874-80. ⟨hal-02130218⟩
  • H Bénédetti, S Raths, F Crausaz, H. Riezman. The END3 gene encodes a protein that is required for the internalization step of endocytosis and for actin cytoskeleton organization in yeast.. Molecular Biology of the Cell, 1994, 5 (9), pp.1023-37. ⟨hal-02130204⟩
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  • V Geli, R Lloubes, S Zaat, R van Spaendonk, C Rollin, et al.. Recognition of the colicin A N-terminal epitope 1C11 in vitro and in vivo in Escherichia coli by its cognate monoclonal antibody. FEMS Microbiology Letters, 1993, 109 (2-3), pp.335-342. ⟨10.1016/0378-1097(93)90042-z⟩. ⟨hal-02130222⟩
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  • Hélène Bénédetti, R Lloubès, C Lazdunski, L. Letellier. Colicin A unfolds during its translocation in Escherichia coli cells and spans the whole cell envelope when its pore has formed.. EMBO Journal, 1992, 11 (2), pp.441-7. ⟨hal-02130272⟩
  • Hélène Bénédetti, C Lazdunski, R Lloubès. Protein import into Escherichia coli: colicins A and E1 interact with a component of their translocation system.. EMBO Journal, 1991, 10 (8), pp.1989-95. ⟨hal-02130277⟩
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Communication dans un congrès16 documents

  • Anthony Champiré, Margaux Sainjon, Abdennour Braka, Samia Aci-Seche, Pascal Bonnet, et al.. Synthesis and preclinical validation of LIMKs inhibitors: Promising drugs for osteosarcoma treatment?. XXVII EFMC International Symposium on Medicinal Chemistry, Sep 2022, NICE, France. ⟨hal-04823073⟩
  • Rayan Berabez, Anthony Champiré, Margaux Sainjon, Abdennour Braka, Samia Aci-Seche, et al.. Synthesis and preclinical validation of LIMKs inhibitors: Promising drugs for osteosarcoma treatment?. SCT 29th Young Research Fellow Meeting, Jul 2022, Nantes, France. ⟨hal-04822252⟩
  • Béatrice Vallée, Christine Mosrin-Huaman, Hélène Bénédetti, Régis Guégan, Bojan Zunar. Life in the bioink: Physiology and energetics of Saccharomyces cerevisiae embedded in polymerized Pluronic F127-DMA, a “smart” thermoresponsive hydrogel. ICY15 meets 30ICYGMB, The spirit of Yeast, Aug 2021, Vienne, virtual, Austria. ⟨hal-03559939⟩
  • Béatrice Vallée, Hélène Bénédetti. Séminaire invité : Signalisation cellulaire et Neurofibromatose. Journées NF, Sep 2021, Orléans, France. ⟨hal-03560050⟩
  • N Laroui, C Delehedde, C Goncalves, F Godin, Federico Perche, et al.. High Efficiency of Histidylated-based Lipid Formulations for mRNA Transfection of Human Schwann Cells. SFNano 2021, Dec 2021, Angers, France. ⟨hal-03668422⟩
  • Justine Corret, Sokaina Hammoud, Frédéric Buron, Pierre Daligaux, Christophe Chesné, et al.. Development of a bio­active fluorescent inhibitor probe targeting the Rho kinase ROCK for monitoring inhibition action. FEBS 2021, the 45th FEBS Congress, Jul 2021, Virtual, France. ⟨hal-03668584⟩
  • H. Bénédetti, Béatrice Vallée, A. Cosson, F. Godin, M. Doudeau. Les LIM kinases : nouvelles cibles thérapeutiques anti-cancer. Journée scientifique du réseau « Cancers hormonaux–dépendants » du Cancéropôle Grand-Ouest, Apr 2019, Nantes, France. ⟨hal-02928496⟩
  • Béatrice Vallée, K. Plé, A. Cosson, M. Doudeau, F. Godin, et al.. Détermination et mise en œuvre d’un modèle in vivo pour tester de nouveaux inhibiteurs originaux des LIM kinases, cibles thérapeutiques émergentes dans le cancer. Cancéropôle Grand Ouest, Colloque du Réseau Molécules marines, métabolisme et cancer, May 2019, Mansigné, France. ⟨hal-02928507⟩
  • M. Bergoug, A. Cosson, D. Casas, M. Doudeau, F. Godin, et al.. Neurofibromin, a new SUMO target involved in neurofibromatosis type 1 disease. 6th LIA Workshop on "Biomarkers and mediators of diseases and new approaches in repair/regenerative therapies, Jun 2019, Varsovie, Poland. ⟨hal-02928511⟩
  • Béatrice Vallée, Karen Plé, A. Cosson, M. Doudeau, F. Godin, et al.. Développement de petites molécules inhibitrices des LIM kinases, nouvelles cibles thérapeutiques pour lutter contre le cancer, les maladies neurologiques et la neurofibromatose. Journée Fédération CBM-ICOA, Jan 2018, Orléans, France. ⟨hal-02928530⟩
  • Béatrice Vallée, S. Routier, A. Cosson, M. Doudeau, F. Godin, et al.. Développement de modulateurs des LIM kinases. Cancéropôle Grand Ouest - 14e colloque du Réseau Produits de la mer en cancérologie - 5e colloque du Réseau Canaux ioniques et cancer, May 2018, Mansigné, France. ⟨hal-02928559⟩
  • M. Bergoug, A. Cosson, M. Doudeau, F. Godin, Béatrice Vallée, et al.. Study of the sumoylation of neurofibromin, the protein responsible for neurofibromatosis type 1. Joint Global Neurofibromatosis Conference 2018, Nov 2018, Paris, France. ⟨hal-02928220⟩
  • Béatrice Vallée, A. Cosson, M. Doudeau, F Godin, A. Braka, et al.. Neurofibromatosis type I: from basic to applied research. 4th LIA Workshop, Jun 2017, Cracovie, Poland. ⟨hal-02928517⟩
  • Béatrice Vallée, Hélène Bénédetti, F. Godin, M. Doudeau. Study of new partners of neurofibromin: an approach to identify novel therapeutic targets for neurofibromatosis type 1. 17th European Neurofibromatosis meeting, Sep 2016, Albano-Terme, Italy. ⟨hal-02928226⟩
  • Wassim Lakhal, Nathalie Boizot, Marie-Claude Lesage Descauses, Odile Rogier, Véronique Laine-Prade, et al.. Both ChIP-SEQ and in planta gene modification demonstrate the involvement of MYB090 and MYB156 in secondary cell wall formation in poplar. INUPRAG-Meeting 2015, Oct 2015, Nancy, France. ⟨hal-01604786⟩
  • J. Tastet, P. Vourc'H, F. Laumonnier, C. Michelle, Anne Duittoz, et al.. Expression des isoformes de LIM Kinase 2 pendant la neurogenèse et la stimulation des neurones. 22. Colloque Biotechnocentre, Oct 2009, Seillac, France. ⟨hal-02753426⟩

Poster32 documents

  • Mohammed Bergoug, Christine Mosrin-Huaman, Amandine Serrano, Fabienne Godin, Michel Doudeau, et al.. Characterization of a new Post Translational Modification of Neurofibromin: atypical structural requirements for its SUMOylation. 2024 Global NF Conference, Jun 2024, Brussels, Belgium. ⟨hal-03679991⟩
  • Mohammed Bergoug, Christine Mosrin-Huaman, Amandine Serrano, Fabienne Godin, Michel Doudeau, et al.. Characterization of a new Post Translational Modification of Neurofibromin: atypical structural requirements for its SUMOylation. 2024 Global NF Conference, Jun 2024, Brussels, Belgium. ⟨hal-04778711⟩
  • Hélène Bénédetti, Christine Mosrin-Huaman, Mohammed Bergoug, Amandine Serrano, Fabienne Godin, et al.. Deciphering the Molecular Mechanism of Pathogenicity in Destabilized variants of Neurofibromin mutated in its SecPH domain. 2024 Global NF Conference, Jun 2024, Brussels (Belgium), Belgium. ⟨hal-04779581⟩
  • Karen Plé, B. Vallée, R. Berabez, A. Champiré, M. Sainjon, et al.. Les LIM kinases, des cibles thérapeutiques prometteuses pour le traitement du glioblastome : de la conception de petites molécules inhibitrices aux tests cellulo. CCCancéropôle Grand Ouest, colloque du réseau Molécules marines, métabolisme et cancer, May 2023, Mansigné, France. ⟨hal-04556346⟩
  • Bojan Zunar, Christine Mosrin-Huaman, Hélène Bénédetti, Régis Guégan, Béatrice Vallée. Life in the bioink: Physiology and energetics of Saccharomyces cerevisiae embedded in polymerized Pluronic F127-DMA, a “smart” thermoresponsive hydrogel. ICY15 meets 30ICYGMB, The spirit of Yeast, Aug 2021, Vienne, virtual, Austria. ⟨hal-03679966⟩
  • Bojan Zunar, Christine Mosrin-Huaman, Hélène Bénédetti, Régis Guégan, Béatrice Vallée. Stressed by hydrogel? Physiological response of yeast cells embedded in thermoresponsive Pluronic F127: a prerequisite for bioreactor development. FEBS 2021, the 45th FEBS Congress, Jul 2021, Ljubljana, Slovenia. ⟨hal-03679975⟩
  • N Laroui, C Delehedde, Cristine Gonçalves, F Godin, F Perche, et al.. High Efficiency of Histidylated-based Lipid Formulations for mRNA Transfection of Human Schwann Cells. 10th mRNA Health Conference, Nov 2021, Berlin, Germany. ⟨hal-03668434⟩
  • Elodie Villalonga, Célina Chalal, Déborah Cassas, Michel Doudeau, Fabienne Godin, et al.. New insights into the regulation of actin cytoskeleton dynamics via the Rho/ROCK/LIMK2/cofilin signalling pathway: a novel mechanism of regulation of cofilin by LIMK2. FEBS 2021, the 45th FEBS Congress, Jul 2021, Ljubljana, virtual, Slovenia. ⟨hal-03680139⟩
  • Christine Mosrin-Huaman, Mohammed Bergoug, Fabienne Godin, Michel Doudeau, Iva Sosic, et al.. Sumoylation of Neurofibromin and its SecPH Domain Plays a Role in Their Functions and Implies Unexpected Structural Requirements. 2021 NF1 virtual conference, Jun 2021, Virtual, France. ⟨hal-03680001⟩
  • Justine Corret, Sokaina Hammoud, Frédéric Buron, Pierre Daligaux, Christophe Chesné, et al.. Development of a bio­active fluorescent inhibitor probe targeting the Rho kinase ROCK for monitoring inhibition action. FEBS 2021, the 45th FEBS Congress, Jul 2021, Lnubljana, virtual, Slovenia. ⟨hal-03679980⟩
  • Mélissa Thomas, Lauren Blot, Kevin Lesage, Fabienne Godin, Michel Doudeau, et al.. New molecular insights into the crosstalk between Rho/ROCK/LIMK2/cofilin signalling pathway and Nf1. 2021 NF1 virtual conference, Jun 2021, Virtual, France. ⟨hal-03679999⟩
  • H. Bénédetti, Béatrice Vallée, J. Tastet, H. Cubéros, A. Toutain, et al.. Molecular and functional characterization of LIMK2-1, a hominidae-specific isoform of LIMK2 associated with intellectual disability. NeuroFrance 2019, May 2019, Marseille, France. ⟨hal-02924881⟩
  • H. Bénédetti, M. Bergoug, I. Sošic, M. Doudeau, F. Godin, et al.. Study of the different forms of sumoylation of the neurofibromin SecPH domain. EMBO Workshop "The ubiquitin system: Biology, mechanisms and roles in disease", Sep 2019, Cavtat, Croatia. ⟨hal-02924090⟩
  • M. Bergoug, I. Sošic, M. Doudeau, F. Godin, Béatrice Vallée, et al.. Neurofibromin, a new SUMO target involved in neurofibromatosis type 1 disease. EMBO Workshop "The ubiquitin system: Biology, mechanisms and roles in disease", Sep 2019, Cavtat, Croatia. ⟨hal-02924095⟩
  • Béatrice Vallée, A. Cosson, M. Doudeau, F. Godin, A. Champiré, et al.. LIM kinases, new therapeutic targets to treat cancers, neurological disorders and Neurofibromatosis: development of small molecule inhibitors. FEBS Meeting 2019, Jul 2019, Cracovie, Poland. ⟨hal-02924140⟩
  • Christine Mosrin-Huaman, B. Handelaoui, H. Bénédetti, Béatrice Vallée. Yeast biosensors to detect environmental pollutants into effluent waters. ICYGMB XXIX International Congress on Yeast Genetics and Molecular Biology, Aug 2019, Göteborg, Sweden. ⟨hal-02924111⟩
  • Béatrice Vallée, A. Cosson, M. Doudeau, F. Godin, A. Champiré, et al.. Development of small molecule inhibitors of LIM kinases, new therapeutic targets to treat Neurofibromatosis type I. Joint Global Neurofibromatosis Conference 2018, Nov 2018, Paris, France. ⟨hal-02924077⟩
  • H. Bénédetti, M. Doudeau, F. Godin, Béatrice Vallée, A. Cosson, et al.. LARP6, a RNA−binding protein involved in translation and stability of collagen mRNA, is a new partner of Neurofibromin: Molecular studies and functional implications. Joint Global Neurofibromatosis Conference 2018, Nov 2018, Paris, France. ⟨hal-02924084⟩
  • Séverine Morisset-Lopez, W. Deraredj Nadim, S. Chaumont−dubel, F. Madouri, L. Cobret, et al.. Neurofibromin 1 promotes constitutive activity of native 5−HT6 receptors expressed in mouse prefrontal cortex. Neurofrance, May 2017, Bordeaux, France. ⟨hal-02973767⟩
  • M. Bergoug, A. Cosson, M. Doudeau, F. Godin, Béatrice Vallée, et al.. Study of the sumoylation of neurofibromin, the protein responsible for neurofibromatosis type 1. EMBO Conference "Ubiquitin and SUMO: from molecular mechanisms to system-wide responses, Sep 2017, Cavtat, Croatia. ⟨hal-02924070⟩
  • A. Champiré, A. Braka, Béatrice Vallée, M. Doudeau, F. Godin, et al.. Design, synthesis and biological evaluation of LIMK inhibitors. XXIVe Journées Jeunes Chercheurs (SCT), Feb 2017, Châtenay-Malabry, France. ⟨hal-02904837⟩
  • A. Champiré, A. Braka, B. Vallée, M. Doudeau, F. Godin, et al.. LIM kinases as new therapeutic targets for the treatment of neurofibromatosis type 1. VII International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC) –, Aug 2017, Vienne, Austria. ⟨hal-02904794⟩
  • Béatrice Vallée, A. Cosson, M. Doudeau, F. Godin, Anthony Champiré, et al.. LIM Kinases: new anticancer therapeutic targets. Breast Cancer Symposium, Jun 2017, Nantes, France. ⟨hal-03680148⟩
  • Béatrice Vallée, Michel Doudeau, F. Godin, H. Cubéros, A. Champiré, et al.. Projet Région LiCorNe: LIMK protein inhibitors, new therapeutic agents for treatment of cognitive disorders associated with type I Neurofibromatosis. Journée Fédération PCV FR2708, Jan 2016, Orléans, France. ⟨hal-02924056⟩
  • W. Deraredj Nadim, S. Chaumont-Dubel, F. Madouri, L. Cobret, M.-L. de Tauzia, et al.. A Physical Interaction between Neurofibromin and Serotonin 5-HT6 Receptor Promotes Receptor Constitutive Activity. 5th annual meeting of the GDR 3545 RCPG-PhysioMed 2016, Nov 2016, Tours, France. ⟨hal-02973912⟩
  • A. Champiré, A. Braka, Béatrice Vallée, M. Doudeau, F. Godin, et al.. Conception, synthèse et évaluation biologique d’inhibiteurs de LIM kinases. 29e colloque de Biotechnocentre, Oct 2016, Seillac, France. ⟨hal-02904847⟩
  • Béatrice Vallée, Hélène Cuberos, Julie Tastet, Michel Doudeau, Fabienne Godin, et al.. LIMK2-1, a new primate-specific isoform of LIMK2, is associated with intellectual disability. 10 th FENS (Forum of Neurosciences), Jul 2016, Copenhague, Denmark. . ⟨hal-02453486⟩
  • Annabelle Dejardin, Wassim Lakhal, Nathalie Boizot, Marie-Claude Lesage Descauses, Odile Rogier, et al.. Unraveling the function of MYB090 and MYB156 in secondary cell wall formation in poplar using both ChIP-SEQ and in planta gene modification approach. XIV Cell Wall Meeting, Jun 2016, Chania, Grèce. , 2016, XIV Cell Wall Meeting. Programme and Book of Abstracts. ⟨hal-02740921⟩
  • Béatrice Vallée, Michel Doudeau, Fabienne Godin, Anthony Champiré, Karen Plé, et al.. LIM kinases: new therapeutic targets to treat Neurofibromatosis type I. The 7th EMBO meeting, Sep 2016, Mannheim, Germany. . ⟨hal-02453490⟩
  • Béatrice Vallée, Hélène Cuberos, Michel Doudeau, Fabienne Godin, Patrick Vourc’h, et al.. The three isoforms of human LIMK2 regulate actin cytoskeleton remodeling via different pathways. EMBL Symposium, Actin in action: From Molecules to Cellular Functions, Sep 2016, Heidelberg, Germany. . ⟨hal-02453489⟩
  • Hélène Bénédetti, Fabienne Godin, Michel Doudeau, Béatrice Vallée, Marie-Ludivine De Tauzia, et al.. LINGO-1, a protein involved in various neurodevelopmental processes, interacts with neurofibromin (Nf1), the protein responsible for neurofibromatosis type I: molecular studies and functional implications. 10 th FENS (Forum of Neuroscience), Jul 2016, Copenhague, Denmark. ⟨hal-02453487⟩
  • J. Tastet, P. Vourc'H, F. Laumonnier, C. Michelle, Anne Duittoz, et al.. LIMK2 (LIM kinase2) isoforms are differentially expressed during neuronal differentiation. 7. FENS Forum of European Neuroscience, Jul 2010, Amsterdam, Netherlands. n.p., 2010. ⟨hal-02818145⟩

Chapitre d'ouvrage7 documents

  • Emmanuelle Bouveret, Claude Lazdunski, Hélène Bénédetti. The Tol/PAL and TonB systems : two envelope-spanning protein complexes involved in colicin import in E. coli.. Molecular Dynamics of Biomembranes, Springer Berlin Heidelberg, pp.59-69, 1996. ⟨hal-02130680⟩
  • H. Bénédetti, V. Geli. Colicin transport, channel formation and inhibition. Handbook of Biological Physics, pp.665-691, 1996. ⟨hal-02130677⟩
  • Vincent Géli, Hélène Bénédetti. Insertion of Proteins into Membranes A Survey. Membrane biogenesis, pp.21-69, 1994, Subcellular Biochemistry, 978-1-4613-6018-6. ⟨hal-02130265⟩
  • L. Letellier, C. Lazdunski, H. Bénédetti, J. Bourdineaud, P. Boulanger. In Vivo Properties of Colicin A: Channel Activity and Translocation. Bacteriocins, Microcins and Lantibiotics, Springer Berlin Heidelberg, pp.119-125, 1992. ⟨hal-02130671⟩
  • C. Lazdunski, D. Baty, V. Geli, R. Lloubes, H. Bénédetti, et al.. Molecular Mechanism of Action of Pore-Forming Colicins and of their Immunity Proteins. Membrane Proteins: Structures, Interactions and Models, pp.413-425, 1992. ⟨hal-02130675⟩
  • Hélène Bénédetti, Lucienne Letellier, Roland Lloubes, Vincent Géli, Daniel Baty, et al.. Import of Colicins into Escherichia Coli. Dynamics of Membrane Assembly, 63, Springer Berlin Heidelberg, pp.315-332, 1992. ⟨hal-02130670⟩
  • Hélène Bénédetti, Lucienne Letellier, Roland Lloubes, Vincent Géli, Daniel Baty, et al.. Study of the Import Mechanisms of Colicins Through Protein Engineering and K+ Efflux Kinetics. Bacteriocins, Microcins and Lantibiotics, Springer Berlin Heidelberg, pp.215-223, 1992. ⟨hal-02130674⟩

Brevet3 documents

  • Sylvain Routier, Hélène Bénédetti, Béatrice Vallée, Pascal Bonnet, Karen Plé, et al.. 4-(7H-Pyrrolo[2,3-D]pyrimidin-4-yl)-3,6-dihydropyridine-(2H)-carboxamide derivatives as Limk and/or Rock kinases inhibitors for use in the treatment of cancer. France, Patent n° : WO2021239727 A1. AMV. 2021. ⟨hal-03555349⟩
  • Sylvain Routier, Hélène Bénédetti, Frederic Buron, Marie-Aude Hiebel, Thibault Saurat, et al.. TRISUBSTITUTED PYRIDO[2,3-D]PYRIMIDINES, METHODS FOR PREPARING SAME AND THERAPEUTIC USES THEREOF. France, Patent n° : WO2014027081. 2014. ⟨hal-02131560⟩
  • Séverine Morisset-Lopez, Hélène Bénédetti. Tools for the identification od LINGO-1, LINGO-2, LINGO-3 and LINGO-4, ligands, and uses thereof. France, Patent n° : WO2011121257. BCT. 2011. ⟨hal-02130935⟩

Pré-publication, Document de travail1 document

  • Mohammed Bergoug, Christine Mosrin, Fabienne Godin, Michel Doudeau, Iva Sosic, et al.. Noncanonical structural requirements of neurofibromin SUMOylation reveal a folding-deficiency of several pathogenic mutants. 2022. ⟨hal-03668582⟩

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