Post-doctoral GREMI laboratory, team "Skin Biology and Microenvironment"
Organisation: Team Cell Biology, Molecular Targets and Innovative Therapies
DELIMESLE Clara
email : clara.delimesle[remplacer_par_at]cnrs-orleans.fr
Phone : +33 2.38.25.78.18
Engineer (fixed term contract), team "Skin Biology and Microenvironment"
CHETTOUH Nadira
email : nadira.chettouh[remplacer_par_at]cnrs-orleans.fr
Phone : +33 2.38.25.78.18
Researcher (Fixed term contract), Team "CBM: Cutaneous Biology and Microenvironment"
SERRANO Amandine
mail : amandine.serrano[remplacer_par_at]cnrs-orleans.fr
Phone : +33 2.38.25.76.05
Research engineer (fixed term contract), Thematic group "Cell signalling and neurofibromatosis"
MOSRIN-HUAMAN Christine
email : christine.mosrin[remplacer_par_at]cnrs-orleans.fr
Phone : +33 2.38.25.76.11
Researcher within the thematic group “Pharmacological targets and biomarkers”
- Filtres
Publications (Archives Hal)
Contact
- isabelle.frapart@cnrs-orleans.fr
- 02.38.25.55.53
Disciplines
Mots-clefs
3D printing ATP biosensor Actin dynamics BINDING PROTEINS NRD1 Bioavailability Biogenesis Bioink Biology COTRANSCRIPTIONAL RECRUITMENT CRYPTIC UNSTABLE TRANSCRIPTS Cell biology ChIP-seq Chemical probing Chloroacetaldehyde Chromatin Copper biosensor PROCESSING FACTORS SACCHAROMYCES-CEREVISIAE Saccharomyces cerevisiae TERMINATION FACTOR-RHO
- PROCESSING FACTORS2
- SACCHAROMYCES-CEREVISIAE2
- Saccharomyces cerevisiae2
- TERMINATION FACTOR-RHO2
- 3D printing1
- ATP biosensor1
- Actin dynamics1
- BINDING PROTEINS NRD11
- Bioavailability1
- Biogenesis1
- Bioink1
- Biology1
- COTRANSCRIPTIONAL RECRUITMENT1
- CRYPTIC UNSTABLE TRANSCRIPTS1
- Cell biology1
- ChIP-seq1
- Chemical probing1
- Chloroacetaldehyde1
- Chromatin1
- Copper biosensor1
- Cytoplasm1
- Cytoskeleton remodelling1
- DOMAIN1
- ELONGATION COMPLEX1
- ESCHERICHIA-COLI1
- EXOSOME1
- Exosome complex1
- Function1
- Gene1
- Genetics1
- IN-VIVO1
- In situ footprinting1
- Interactions1
- Kinase1
- LIMK1 and LIMK21
- Localization1
- MRNP1
- MRNP biogenesis1
- MRNP quality control1
- Messenger RNP1
- NUCLEAR-PORE1
- Neurofibromin1
- POLYMERASE-II TRANSCRIPTS1
- Pluronic F1271
- Post-translational modifications1
- QUALITY-CONTROL1
- RNA1
- RNA-POLYMERASE-II1
- RNA-seq1
- Ribonucleoprotein1
- Rna processing1
- SUBUNIT RPB91
- Signalling pathways1
- Structure1
- Transactivator engineering1
- Transcription elongation1
- Whole-cell biosensor1
- Yeast1
Auteurs
- Mosrin-Huaman Christine25
- Vallée Béatrice9
- Bénédetti Hélène9
- Rahmouni A. Rachid8
- Rahmouni A.R.6
- Mosrin-Huaman C.5
- Le Dantec Aurélia5
- Piegu Benoit5
- Doudeau Michel4
- Bergoug Mohammed3
- Bigot Y.3
- Godin Fabienne3
- Moreau Kévin3
- Sosic Iva3
- Zunar Bojan3
- Hervouet-Coste Nadege3
- Mosrin-Huaman M3
- Le Dantec A.2
- Leng M.2
- Locker D.2
- Moreau K.2
- Stuparevic Igor2
- Thuriaux P2
- Thuriaux P.2
- Godin Fabienne2
- Žunar Bojan2
- Decoville M.2
- Rahmouni Rachid A.2
- Hervouet-Coste Nadège2
- Mosrin Christine2
- Guégan Régis2
- Bigot Yves2
- Honorine Romy2
- Suskiewicz Marcin2
- Artsimovitch I.1
- Becker J.1
- Beltrame M1
- Benli M.1
- Canaple L.1
- Cassar E1
- Das A.1
- Ferino Fabrice1
- Gallwitz D.1
- Gerits Jozef1
- Girardin Caroline1
- Guégan Régis1
- Handelaoui B.1
- Hengst L.1
- Kreps Sabine1
- Mergeay Max1
- Moreau Kevin1
- Mundt M.1
- Normand Thierry1
- Remenaric Mateja1
- Sentenac A.1
- Serrano Amandine1
- Sparkowski J1
- Tan J.1
- Thuriaux Pierre1
- Toulmé F1
- Toulmé F.1
- Turnbough C.L.1
- Vallée Béatrice1
- Villalonga Elodie1
- Vollmer P.1
- Wichmann H.1
- Žunar Bojan1
- Bergoug Mohammed1
- Doudeau Michel1
- Stuparević Igor1
- Hervouet-Coste Nadège1
- Suskiewicz Marcin1
- Moreau Kevin1
- Novačić Ana1
- Beauvais Valentin1
- Rachid Rahmouni A.1
- Legrand Alain1
- Bénédetti H.1
- Riva M.1
- Dantec Aurélia Le1
- Giraud-Panis M1
- Surand Justine1
- Libri Domenico1
- Primig Michael1
Revues
Année de production
Institutions
- Université d'Orléans29
- Université de Tours29
- Institut National de la Santé et de la Recherche Médicale29
- Institut de Chimie - CNRS Chimie29
- Institut Français du Cheval et de l'Equitation [Saumur]5
- University of Zagreb5
- Commissariat à l'énergie atomique et aux énergies alternatives5
- Institut National de la Recherche Agronomique3
- Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement2
- Université de Rennes1
Laboratoires
- Centre de biophysique moléculaire29
- Physiologie de la reproduction et des comportements [Nouzilly]3
- Physiologie de la reproduction et des comportements [Nouzilly]2
- Centre de génétique moléculaire1
- Institut de recherche en santé, environnement et travail1
- Max-Planck-Institut für Biophysikalische Chemie - Max Planck Institute for Biophysical Chemistry [Göttingen]1
Départements
Équipes de recherche
35 documents
Article dans une revue20 documents
- Elodie Villalonga, Christine Mosrin, Thierry Normand, Caroline Girardin, Amandine Serrano, et al.. LIM Kinases, LIMK1 and LIMK2, Are Crucial Node Actors of the Cell Fate: Molecular to Pathological Features. Cells, 2023, 12 (5), pp.805. ⟨10.3390/cells12050805⟩. ⟨hal-04208405⟩
- Valentin Beauvais, Kevin Moreau, Bojan Žunar, Nadège Hervouet-Coste, Ana Novačić, et al.. Tho2 is critical for the recruitment of Rrp6 to chromatin in response to perturbed mRNP biogenesis. RNA, 2023, pp.rna.079707.123. ⟨10.1261/rna.079707.123⟩. ⟨hal-04286417⟩
- Bojan Žunar, Christine Mosrin-Huaman, Hélène Bénédetti, Béatrice Vallée. Re-engineering of CUP1 promoter and Cup2/Ace1 transactivator to convert Saccharomyces cerevisiae into a whole-cell eukaryotic biosensor capable of detecting 10 nM of bioavailable copper. Biosensors and Bioelectronics, 2022, 214, pp.114502. ⟨10.1016/j.bios.2022.114502⟩. ⟨hal-03820214⟩
- Mohammed Bergoug, Michel Doudeau, Fabienne Godin, Christine Mosrin-Huaman, Béatrice Vallée, et al.. Neurofibromin Structure, Functions and Regulation. Cells, 2020, 9, ⟨10.3390/cells9112365⟩. ⟨hal-03070759v2⟩
- Kévin Moreau, Aurélia Le Dantec, Christine Mosrin-Huaman, Yves Bigot, Benoit Piegu, et al.. Perturbation of mRNP biogenesis reveals a dynamic landscape of the Rrp6-dependent surveillance machinery trafficking along the yeast genome. RNA Biology, 2019, 16 (7), pp.879-889. ⟨10.1080/15476286.2019.1593745⟩. ⟨hal-02117640⟩
- Kévin Moreau, Justine Surand, Aurélia Le Dantec, Christine Mosrin-Huaman, Alain Legrand, et al.. Recombinant yeast and human cells as screening tools to search for antibacterial agents targeting the transcription termination factor Rho. Journal of Antibiotics, 2018, 71 (4), pp.447-455. ⟨hal-01966171⟩
- Christine Mosrin-Huaman, Nadège Hervouet-Coste, A. Rachid Rahmouni. Co-transcriptional degradation by the 5′-3′ exonuclease Rat1p mediates quality control of HXK1 mRNP biogenesis in S. cerevisiae. RNA Biology, 2016, 13 (6), pp.582 - 592. ⟨10.1080/15476286.2016.1181255⟩. ⟨hal-01407513⟩
- Rachid A. Rahmouni, Christine Mosrin-Huaman. In Situ Footprinting of E. coli Transcription Elongation Complex with Chloroacetaldehyde. Methods in Molecular Biology, 2015, Methods in Molecular Biology, 1276, pp.229-240. ⟨10.1007/978-1-4939-2392-2_13⟩. ⟨hal-01171857⟩
- Christine Mosrin-Huaman, Nadege Hervouet-Coste, Aurélia Le Dantec, Igor Stuparevic, A. Rachid Rahmouni. Bacterial Rho helicase: a new tool to dissect mRNP biogenesis and quality control in yeast. Trends in cell and molecular biology, 2014, 9, pp.79 - 93. ⟨hal-01179495⟩
- Igor Stuparevic, Christine Mosrin-Huaman, Nadège Hervouet-Coste, Mateja Remenaric, A. Rachid Rahmouni. Co-transcriptional recruitment of the RNA exosome cofactors Rrp47p, Mpp6p and two distinct TRAMP complexes assists the exonuclease Rrp6p in the targeting and degradation of an aberrant mRNP in yeast. Journal of Biological Chemistry, 2013, ⟨10.1074/jbc.M113.491290⟩. ⟨hal-00874892⟩
- Romy Honorine, Christine Mosrin-Huaman, Nadege Hervouet-Coste, Domenico Libri, Rachid A. Rahmouni. Nuclear mRNA quality control in yeast is mediated by Nrd1 co-transcriptional recruitment, as revealed by the targeting of Rho-induced aberrant transcripts. Nucleic Acids Research, 2011, 39 (7), pp.2809-2820. ⟨10.1093/nar/gkq1192⟩. ⟨hal-00602376⟩
- Christine Mosrin-Huaman, Romy Honorine, A. Rachid Rahmouni. Expression of Bacterial Rho Factor in Yeast Identifies New Factors Involved in the Functional Interplay between Transcription and mRNP Biogenesis. Molecular and Cellular Biology, 2009, 29 (15), pp.4033-4044. ⟨10.1128/MCB.00272-09⟩. ⟨hal-00525149⟩
- F. Toulmé, C. Mosrin-Huaman, I. Artsimovitch, A.R. Rahmouni. Transcriptional pausing in vivo: a nascent RNA hairpin restricts lateral movements of RNA polymerase in both forward and reverse directions. Journal of Molecular Biology, 2005, 351, pp.39-51. ⟨hal-00088714⟩
- C. Mosrin-Huaman, C.L. Turnbough, A.R. Rahmouni. Translocation of Escherichia coli RNA polymerase against a protein roadblock in vivo highlights a passive sliding mechanism for transcript elongation. Molecular Microbiology, 2004, 51, pp.1471-1481. ⟨hal-00113075⟩
- F Toulmé, M Mosrin-Huaman, J Sparkowski, A. Das, M. Leng, et al.. GreA and GreB proteins revive backtracked RNA polymerase in vivo by promoting transcript trimming. EMBO Journal, 2000, 19 (24), pp.6853-6859. ⟨10.1093/emboj/19.24.6853⟩. ⟨hal-02127250⟩
- M. Decoville, M Giraud-Panis, M Mosrin-Huaman, M. Leng, D. Locker. HMG boxes of DSP1 protein interact with the Rel homology domain of transcription factors. Nucleic Acids Research, 2000, 28 (2), pp.454-462. ⟨10.1093/nar/28.2.454⟩. ⟨hal-02119310⟩
- M Mosrin-Huaman, L. Canaple, D. Locker, M. Decoville. DSP1Gene ofDrosophila melanogaster encodes an HMG-domain protein that plays multiple roles in development. Developmental Genetics, 1998, 23 (4), pp.324-334. 3.0.CO;2-T">⟨10.1002/(SICI)1520-6408(1998)23:4<324::AID-DVG7>3.0.CO;2-T⟩. ⟨hal-02119315⟩
- Christine Mosrin-Huaman, M. Riva, M Beltrame, E Cassar, A. Sentenac, et al.. The RPC31 gene of Saccharomyces cerevisiae encodes a subunit of RNA polymerase C (III) with an acidic tail.. Molecular and Cellular Biology, 1990, 10 (9), pp.4737-4743. ⟨10.1128/mcb.10.9.4737⟩. ⟨hal-02266468⟩
- Christine Mosrin-Huaman, P Thuriaux. The genetics of RNA polymerases in yeasts.. Current Genetics, 1990, 17 (5), pp.367-373. ⟨hal-02266470⟩
- Sabine Kreps, Fabrice Ferino, Christine Mosrin-Huaman, Jozef Gerits, Max Mergeay, et al.. Conjugative transfer and autonomous replication of a promiscuous IncQ plasmid in the cyanobacterium Synechocystis PCC 6803. Molecular and General Genetics MGG, 1990, 221 (1), pp.129-133. ⟨10.1007/BF00280378⟩. ⟨hal-02266473⟩
Communication dans un congrès1 document
- Béatrice Vallée, Christine Mosrin-Huaman, Hélène Bénédetti, Régis Guégan, Bojan Zunar. Life in the bioink: Physiology and energetics of Saccharomyces cerevisiae embedded in polymerized Pluronic F127-DMA, a “smart” thermoresponsive hydrogel. ICY15 meets 30ICYGMB, The spirit of Yeast, Aug 2021, Vienne, virtual, Austria. ⟨hal-03559939⟩
Poster10 documents
- Bojan Zunar, Christine Mosrin-Huaman, Hélène Bénédetti, Régis Guégan, Béatrice Vallée. Life in the bioink: Physiology and energetics of Saccharomyces cerevisiae embedded in polymerized Pluronic F127-DMA, a “smart” thermoresponsive hydrogel. ICY15 meets 30ICYGMB, The spirit of Yeast, Aug 2021, Vienne, virtual, Austria. ⟨hal-03679966⟩
- Christine Mosrin-Huaman, Mohammed Bergoug, Fabienne Godin, Michel Doudeau, Iva Sosic, et al.. Sumoylation of neurofibromin and its SecPH domain plays a role in their functions and implies unexpected structural requirements. FEBS 2021, the 45th FEBS Congress, Jul 2021, Ljubljana, Slovenia. ⟨hal-03679991⟩
- Christine Mosrin-Huaman, Mohammed Bergoug, Fabienne Godin, Michel Doudeau, Iva Sosic, et al.. Sumoylation of Neurofibromin and its SecPH Domain Plays a Role in Their Functions and Implies Unexpected Structural Requirements. 2021 NF1 virtual conference, Jun 2021, Virtual, France. ⟨hal-03680001⟩
- Bojan Zunar, Christine Mosrin-Huaman, Hélène Bénédetti, Régis Guégan, Béatrice Vallée. Stressed by hydrogel? Physiological response of yeast cells embedded in thermoresponsive Pluronic F127: a prerequisite for bioreactor development. FEBS 2021, the 45th FEBS Congress, Jul 2021, Ljubljana, Slovenia. ⟨hal-03679975⟩
- Christine Mosrin-Huaman, B. Handelaoui, H. Bénédetti, Béatrice Vallée. Yeast biosensors to detect environmental pollutants into effluent waters. ICYGMB XXIX International Congress on Yeast Genetics and Molecular Biology, Aug 2019, Göteborg, Sweden. ⟨hal-02924111⟩
- K. Moreau, A. Le Dantec, C. Mosrin-Huaman, Benoit Piegu, Y. Bigot, et al.. High resolution maps of the nuclear RNA surveillance components trafficking along the yeast genome. EMBL Symposium: Transcription and Chromatin 2018, Aug 2018, Heidelberg, Germany. ⟨hal-02920318⟩
- K. Moreau, A. Le Dantec, C. Mosrin-Huaman, Benoit Piegu, Y. Bigot, et al.. Etude métagénomique des mécanismes nucléaires de contrôle qualité et dégradation de l’ARN. 30e Colloque Biotechnocentre, Oct 2017, Seillac, France. ⟨hal-02934894⟩
- Kevin Moreau, Aurélia Le Dantec, Christine Mosrin-Huaman, Benoit Piegu, Y. Bigot, et al.. Metagenomic analysis of Nuclear Quality Control & Degradation mechanisms of Eukaryotic RNA. Colloque international du Studium : Messenger RNA therapeutics: advances and perspectives, Mar 2017, Orléans, France. ⟨hal-02920331⟩
- A. Rachid Rahmouni, Christine Mosrin-Huaman, Nadege Hervouet-Coste. Co-transcriptional degradation by the 5’-3’ exonuclease Rat1p mediates quality control of HXK1 mRNP biogenesis in S. cerevisiae. EMBO EMBL Symposium: The Complex Life of mRNA, Oct 2016, Heidelberg, Germany. . ⟨hal-02453485⟩
- Kévin Moreau, Aurélia Le Dantec, Christine Mosrin-Huaman, Benoit Piegu, Yves Bigot, et al.. Analyse métagénomique du mécanisme de discrimination entre les transcrits codants et non-codants par la machinerie de dégradation de l’ARN. 29e colloque Biotechnocentre, Oct 2016, Seillac, France. ⟨hal-02453482⟩
Chapitre d'ouvrage3 documents
- P. Thuriaux, Christine Mosrin-Huaman. La génétique moléculaire des levures. Biotechnologie des levures, elsevier masson, pp.49-80, 1991. ⟨hal-02181574⟩
- Christine Mosrin-Huaman, P. Thuriaux. Les outils du génie génétique. Biotechnologies des levures, Masson, pp.81-96, 1991. ⟨hal-02266466⟩
- D. Gallwitz, J. Becker, M. Benli, L. Hengst, C. Mosrin-Huaman, et al.. The YPT-Branch of the ras Superfamily of GTP-Binding Proteins in Yeast: Functional Importance of the Putative Effector Region. The Superfamily of ras-Related Genes, Springer US, pp.121-128, 1991, 978-1-4684-6020-9. ⟨hal-02181563⟩
Pré-publication, Document de travail1 document
- Mohammed Bergoug, Christine Mosrin, Fabienne Godin, Michel Doudeau, Iva Sosic, et al.. Noncanonical structural requirements of neurofibromin SUMOylation reveal a folding-deficiency of several pathogenic mutants. 2022. ⟨hal-03668582⟩
ROBIN Chloé
email : chloe.robin[remplacer_par_at]cnrs-orleans.fr
Phone : +33 2.38.25.55.86
Assistant engineer in biology, Natural sciences, team DAIH Team: Dysregulation of Authophay in Inflammation Due to HIV
- Filtres
Publications (Archives Hal)
Contact
- isabelle.frapart@cnrs-orleans.fr
- 02.38.25.55.53
Disciplines
Mots-clefs
Auteurs
- Robin Chloé8
- Lipinski Marc4
- El Haddad Saïd3
- Ogryzko Vasily3
- Serrano Amandine3
- Brulé-Morabito Fabienne3
- Normand Thierry3
- Legrand Alain3
- Mollet Lucile3
- Shoaib Muhammad2
- Tarlykov Pavel2
- Charpentier Stéphane2
- Vassetzky Yegor2
- Moal Fréderic2
- Auzou Pascal1
- Bou Saada Yara1
- Charpentier Stéphane1
- Despas Emmanuelle1
- Dubois Martine1
- Ekwall Karl1
- Ioudinkova Elena1
- Jauch Anna1
- Jurisic A.1
- Jurisic Anamarija1
- Kulyyassov Arman1
- Legac Eric1
- Lomov Nikolay1
- Ogryzko V.1
- Osina Kristina1
- Ozsancak Canan1
- Pichugin Andrey A.1
- Prazuck Thierry1
- Ramanculov Erlan1
- Razin Sergey1
- Rubtsov Mikhail1
- Schoell Brigitte1
- Siggens Lee1
- Sjakste Nikolajs1
- Sklyar Ilya1
- Sørensen Claus Storgaard1
- Tsfasman Tatiana1
- Valery Antoine1
- Winczura Kinga1
- Pirozhkova Iryna1
- Kannouche Patricia L1
- Hocqueloux Laurent1
- Germini Diego1
- Barat Ana1
- Markova Elena1
Revues
Institutions
- Université Paris-Sud - Paris 116
- Institut Gustave Roussy5
- Université d'Orléans3
- Université de Tours3
- Institut National de la Santé et de la Recherche Médicale3
- Institut de Chimie - CNRS Chimie3
- Centre Hospitalier Régional d'Orléans2
- Institut National des Sciences Appliquées - Centre Val de Loire2
- Universität Heidelberg [Heidelberg] = Heidelberg University1
- Dublin City University [Dublin]1
Laboratoires
- Signalisation, noyaux et innovations en cancérologie5
- Centre de biophysique moléculaire3
- Laboratoire d'Informatique Fondamentale d'Orléans2
- School of Computing [Dublin]1
- Department of Biosciences at Novum1
- Stabilité Génétique et Oncogenèse1
- Biotech Research and Innovation Centre1
- Institute of Human Genetics [Heidelberg, Germany]1
Départements
Équipes de recherche
8 documents
Article dans une revue8 documents
- Saïd El Haddad, Amandine Serrano, Fréderic Moal, Thierry Normand, Chloé Robin, et al.. Disturbed expression of autophagy genes in blood of Parkinson’s disease patients. Gene, 2020, 738, pp.144454. ⟨10.1016/j.gene.2020.144454⟩. ⟨hal-02501027⟩
- Saïd El Haddad, Amandine Serrano, Thierry Normand, Chloé Robin, Martine Dubois, et al.. Interaction of Alpha-synuclein with Cytogaligin, a protein encoded by the proapoptotic gene GALIG. Biochemical and Biophysical Research Communications, 2018, 495 (1), pp.787-792. ⟨10.1016/j.bbrc.2017.11.078⟩. ⟨hal-01966108⟩
- Amandine Serrano, Saïd El Haddad, Fréderic Moal, Thierry Prazuck, Eric Legac, et al.. Dysregulation of apoptosis and autophagy gene expression in peripheral blood mononuclear cells of efficiently treated HIV-infected patients. AIDS. Official journal of the international AIDS Society, 2018, 32 (12), pp.1579 - 1587. ⟨10.1097/QAD.0000000000001851⟩. ⟨hal-01936094⟩
- Anamarija Jurisic, Chloé Robin, Pavel Tarlykov, Lee Siggens, Brigitte Schoell, et al.. Topokaryotyping demonstrates single cell variability and stress dependent variations in nuclear envelope associated domains. Nucleic Acids Research, 2018, 46 (22), pp.e135. ⟨10.1093/nar/gky818⟩. ⟨hal-02159521⟩
- Diego Germini, Yara Bou Saada, Tatiana Tsfasman, Kristina Osina, Chloé Robin, et al.. A One-Step PCR-Based Assay to Evaluate the Efficiency and Precision of Genomic DNA-Editing Tools. Molecular Therapy - Methods and Clinical Development, 2017, 5, pp.43-50. ⟨10.1016/j.omtm.2017.03.001⟩. ⟨hal-02159956⟩
- A. Jurisic, Chloé Robin, V. Ogryzko. Topokaryotyping – a proposal for a novel approach to study nuclear organization. Biopolymers and Cell, 2015, 31 (1), pp.72-79. ⟨10.7124/bc.0008CF⟩. ⟨hal-02159965⟩
- Muhammad Shoaib, Arman Kulyyassov, Chloé Robin, Kinga Winczura, Pavel Tarlykov, et al.. PUB-NChIP--"in vivo biotinylation" approach to study chromatin in proximity to a protein of interest. Genome Research, 2013, 23 (2), pp.331-340. ⟨10.1101/gr.134874.111⟩. ⟨hal-02159970⟩
- Elena Ioudinkova, Ana Barat, Andrey A. Pichugin, Elena Markova, Ilya Sklyar, et al.. Distinct Distribution of Ectopically Expressed Histone Variants H2A.Bbd and MacroH2A in Open and Closed Chromatin Domains. PLoS ONE, 2012, 7 (10), pp.e47157. ⟨10.1371/journal.pone.0047157⟩. ⟨hal-02159968⟩
NORMAND Thierry
email : thierry.normand[remplacer_par_at]cnrs-orleans.fr
Phone : +33 2.38.25.55.86
Lecturer within the thematic group “Normal and pathological apoptosis and autophagy”
- Filtres
Publications (Archives Hal)
Contact
- isabelle.frapart@cnrs-orleans.fr
- 02.38.25.55.53
Disciplines
- Sciences du Vivant [q-bio]19
- Informatique [cs]/Bio-informatique [q-bio.QM]2
- Informatique [cs]/Apprentissage [cs.LG]2
- Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Génomique, Transcriptomique et Protéomique [q-bio.GN]2
- Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Biologie moléculaire1
- Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire1
Mots-clefs
ANTIGENS Alpha-synuclein Antiretroviral therapy Apoptosis BAX Basal autophagy CELL-DEATH PROTEIN Caspase activation Cytogaligin Dual cellular localization Dual localization ELECTROPHORETIC TRANSFER ENDOGENOUS PEROXIDASE GALIG gene GENE HORSERADISH-PEROXIDASE IDENTIFICATION IMPORTIN INTRACELLULAR-LOCALIZATION MITOCHONDRIA
- GENE2
- MITOCHONDRIA2
- ANTIGENS1
- Alpha-synuclein1
- Antiretroviral therapy1
- Apoptosis1
- BAX1
- Basal autophagy1
- CELL-DEATH PROTEIN1
- Caspase activation1
- Cytogaligin1
- Dual cellular localization1
- Dual localization1
- ELECTROPHORETIC TRANSFER1
- ENDOGENOUS PEROXIDASE1
- GALIG gene1
- HORSERADISH-PEROXIDASE1
- IDENTIFICATION1
- IMPORTIN1
- INTRACELLULAR-LOCALIZATION1
- LOCALIZATION1
- Luciferase protein-fragment complementation assay1
- MOLECULAR-CLONING1
- Machine learning techniques for biomedical data1
- Mitogaligin1
- NITROCELLULOSE1
- P53 PROTEIN1
- POLYACRYLAMIDE GELS1
- PROTEINS1
- Programmed cell death1
- SEQUENCE1
- SMARF1
- TRANSLOCATION1
- Unconventional nuclear localization signal1
- VIRUS1
Auteurs
- Normand Thierry25
- Legrand Alain13
- Charpentier Stéphane11
- Mollet Lucile9
- Brulé-Morabito Fabienne8
- Dubois Martine6
- El Haddad Saïd3
- Gagné C3
- Gonzalez Patrick3
- Julien P3
- Serrano Amandine3
- Robin Chloé3
- Robinet Pauline3
- Adamski J2
- Bégué A.2
- Dubois M2
- Dubois M.2
- El Haddad S.2
- Haddad S El2
- Jean Claude2
- Jean-Faucher Christiane2
- Leenders F2
- Lupien Paul J.2
- Narod Steven2
- Serrano A2
- Serrano A.2
- Ven Murthy M2
- de Braekeleer M.2
- de Launoit Y2
- Normand T.2
- Mollet L.2
- Bharucha Aoife2
- Simard Jacques2
- Moal Fréderic2
- Aurouet Axel1
- Auzou P.1
- Auzou Pascal1
- Baert J.L1
- Bergeron J.1
- Bergeron M.1
- Bloch Solal1
- Blot Lauren1
- Boyer Guittaut M.1
- Brun D1
- Brun L1
- Brunzell John1
- Carp D1
- Charpentier Stéphane1
- Chen Wanyin1
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- Dionne C1
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- Duneau M.1
- Duneau Mélanie1
- Durocher F.1
- Fernandez-Margallo Teresa1
- Feunteun Jean1
- Flourens A.C1
- Gagné Claude1
- Garnache-Ottou F1
- Garnache-Ottou Francine1
- Grandclement Camille1
- Guery T1
- Guilbault C.1
- Guillemain Anthony1
- Guittaut Michaël1
- Hayden M1
- Hayden Mickael R.1
- Henderson Howard1
- Husen B.1
- Jean C1
- Jean-Faucher C.1
- Julien Pierre1
- Jungblut P1
- Labrie F.1
- Labrie Femand1
- Labrie Fernand1
- Lambert M.1
- Laouarem Yousra1
- Lasko Dana D.1
- Leblanc J.1
- Legac E1
- Legac E.1
- Legac Eric1
- Lenoir Gilbert1
- Lupien P1
- Luplen Paul J.1
- Luu The V1
- Ma R1
- Ma Y.1
- Moal F1
- Moal F.1
- Monsalve M.1
- Monté D1
- Morgan Kenneth1
- Morissette J.1
- Murthy V1
- Ozsancak C1
Revues
- Biochemical and Biophysical Research Communications3
- Human Molecular Genetics2
- Analytical Biochemistry1
- Biochemical Journal1
- Clinical Genetics1
- Cytogenetic and Genome Research1
- Experimental and Clinical Endocrinology1
- International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity1
- Human Genetics1
- AIDS. Official journal of the international AIDS Society1
Année de production
Institutions
- Université d'Orléans15
- Université de Tours15
- Institut National de la Santé et de la Recherche Médicale15
- Institut de Chimie - CNRS Chimie15
- Université Blaise Pascal - Clermont-Ferrand 23
- Faculté de médecine de l'Université Laval [Québec]3
- Centre Hospitalier Régional d'Orléans2
- Université du Québec à Chicoutimi2
- Institut National des Sciences Appliquées - Centre Val de Loire2
- Centre Hospitalier de l'Université de Laval2
- Institut Gustave Roussy1
- Université de Bordeaux1
- Centre Hospitalier Régional Universitaire de Besançon1
- Montreal General Hospital1
- Société GéoHyd1
- Faculty of Medecine, Laval University1
- Creighton University School of Medicine1
- Institut Polytechnique de Bordeaux1
- Etablissement français du sang [Bourgogne-Franche-Comté]1
- Université Grenoble Alpes [2016-2019]1
- Université de Franche-Comté1
- CHU de Québec–Université Laval1
- Organisation Mondiale de la Santé | World Health Organization Office1
- Université Bordeaux Segalen - Bordeaux 21
- Université Paris-Sud - Paris 111
- Université Sciences et Technologies - Bordeaux 11
Laboratoires
- Centre de biophysique moléculaire15
- Laboratoire d'Oncologie Moléculaire Humaine2
- Laboratoire d'Informatique Fondamentale d'Orléans2
- CHUL Research Center and Department of Molecular Medicine, Laboratory of Endocrinology and Genomics2
- Service d'hématologie1
- Interactions hôte-greffon-tumeur, ingénierie cellulaire et génique - UFC (UMR INSERM 1098)1
- Société GéoHyd1
- Molecular Endocrinology and Oncology Research Center1
- Institut de Mathématiques de Bordeaux1
- Laboratoire de Génomique des Cancers1
Départements
Équipes de recherche
27 documents
Article dans une revue23 documents
- Anthony Guillemain, Yousra Laouarem, Laetitia Cobret, Dora Štefok, Wanyin Chen, et al.. LINGO family receptors are differentially expressed in the mouse brain and form native multimeric complexes. FASEB Journal, 2020, pp.1-13. ⟨10.1096/fj.202000826R⟩. ⟨hal-02943248⟩
- Saïd El Haddad, Amandine Serrano, Fréderic Moal, Thierry Normand, Chloé Robin, et al.. Disturbed expression of autophagy genes in blood of Parkinson’s disease patients. Gene, 2020, 738, pp.144454. ⟨10.1016/j.gene.2020.144454⟩. ⟨hal-02501027⟩
- Amandine Serrano, Saïd El Haddad, Fréderic Moal, Thierry Prazuck, Eric Legac, et al.. Dysregulation of apoptosis and autophagy gene expression in peripheral blood mononuclear cells of efficiently treated HIV-infected patients. AIDS. Official journal of the international AIDS Society, 2018, 32 (12), pp.1579 - 1587. ⟨10.1097/QAD.0000000000001851⟩. ⟨hal-01936094⟩
- Saïd El Haddad, Amandine Serrano, Thierry Normand, Chloé Robin, Martine Dubois, et al.. Interaction of Alpha-synuclein with Cytogaligin, a protein encoded by the proapoptotic gene GALIG. Biochemical and Biophysical Research Communications, 2018, 495 (1), pp.787-792. ⟨10.1016/j.bbrc.2017.11.078⟩. ⟨hal-01966108⟩
- Lucile Mollet, Pauline Robinet, Martine Dubois, Axel Aurouet, Thierry Normand, et al.. Opposing Mcl-1, the GALIG proapoptotic gene is upregulated as neutrophils die and underexpressed in Acute Myeloid Leukemia cells.. Molecular Immunology, 2013, 56 (1-2), pp.123-8. ⟨10.1016/j.molimm.2013.04.012⟩. ⟨hal-00840170⟩
- Pauline Robinet, Lucile Mollet, Patrick Gonzalez, Thierry Normand, Stephane Charpentier, et al.. The mitogaligin protein is addressed to the nucleus via a non-classical localization signal. Biochemical and Biophysical Research Communications, 2010, 392 (1), pp.53-57. ⟨10.1016/j.bbrc.2009.12.162⟩. ⟨hal-00529397⟩
- Patrick Gonzalez, Pauline Robinet, Stéphane Charpentier, Lucile Mollet, Thierry Normand, et al.. Apoptotic activity of a nuclear form of mitogaligin, a cell death protein. Biochemical and Biophysical Research Communications, 2009, 378 (4), pp.816-820. ⟨10.1016/j.bbrc.2008.11.133⟩. ⟨hal-00522444⟩
- Alexis D. Sennepin, Stéphane Charpentier, Thierry Normand, Cedric Sarre, Alain Legrand, et al.. Multiple reprobing of Western blots after inactivation of peroxidase activity by its substrate, hydrogen peroxide. Analytical Biochemistry, 2009, 393 (1), pp.129-131. ⟨10.1016/j.ab.2009.06.004⟩. ⟨hal-00525339⟩
- Patrick Gonzalez, Mélanie Duneau, Stéphane Charpentier, Thierry Normand, Lucile Mollet, et al.. Destabilization of Membranes Containing Cardiolipin or Its Precursors by Peptides Derived from Mitogaligin, a Cell Death Protein. Biochemistry, 2007, 46 (25), pp.7374-7382. ⟨10.1021/bi700213p⟩. ⟨hal-00159568⟩
- M. Duneau, M. Boyer Guittaut, P. Gonzalez, S. Charpentier, T. Normand, et al.. Galig, a novel cell death gene that encodes a mitochondrial protein promoting cytochrome c release. Experimental Cell Research, 2005, 302, pp.194-205. ⟨hal-00088588⟩
- Michaël Guittaut, Stéphane Charpentier, Thierry Normand, Martine Dubois, Jacques Raimond, et al.. Identification of an Internal Gene to the Human Galectin-3 Gene with Two Different Overlapping Reading Frames That Do Not Encode Galectin-3. Journal of Biological Chemistry, 2001, 276 (4), pp.2652-2657. ⟨10.1074/jbc.m002523200⟩. ⟨hal-02137994⟩
- J. Morissette, F. Durocher, J. Leblanc, T. Normand, F. Labrie, et al.. Genetic linkage mapping of the human steroid 5α-reductase type 2 gene (SRD5A2) close to D2S352 on chromosome region 2p23→p22. Cytogenetic and Genome Research, 1996, 73 (4), pp.304-307. ⟨10.1159/000134362⟩. ⟨hal-02160041⟩
- A.M. Simon, C. Guilbault, Thierry Normand, Christiane Jean-Faucher, Georges Veyssière, et al.. Developmental and hormonal regulation of specific proteins in mouse seminal vesicles. Isolation and characterization of genomic and cDNA clones for androgen-regulated secretory protein. Experimental and Clinical Endocrinology, 1995, 14, pp.73-82. ⟨hal-02167152⟩
- Thierry Normand, B. Husen, F Leenders, H Pelczar, J.L Baert, et al.. Molecular characterization of mouse 17 beta-hydroxysteroid dehydrogenase IV.. Journal of Steroid Biochemistry and Molecular Biology, 1995, 55 (5-6), pp.541-8. ⟨10.1016/0960-0760(95)00204-9⟩. ⟨hal-02160020⟩
- J Adamski, Thierry Normand, F Leenders, D Monté, A. Bégué, et al.. Molecular cloning of a novel widely expressed human 80 kDa 17 β -hydroxysteroid dehydrogenase IV. Biochemical Journal, 1995, 311 (2), pp.437-443. ⟨10.1042/bj3110437⟩. ⟨hal-02160026⟩
- Thierry Normand, Steven Narod, Fernand Labrie, Jacques Simard. Detection of polymorphisms in the estradiol 17β-hydroxysteroid dehydrogenase II gene at the EDH17B2 locus on 17q11–q21. Human Molecular Genetics, 1993, 2 (4), pp.479-483. ⟨10.1093/hmg/2.4.479⟩. ⟨hal-02160210⟩
- J Simard, Jean Feunteun, Gilbert Lenoir, T Tonin, Thierry Normand, et al.. Genetic mapping of the breast-ovarian cancer syndrome to a small interval on chromosome 17q12–21: exclusion of candidate genes EDH17B2 and RARA. Human Molecular Genetics, 1993, 2 (8), pp.1193-1199. ⟨10.1093/hmg/2.8.1193⟩. ⟨hal-02160208⟩
- P Peeva, L Brun, M Ven Murthy, P Després, Thierry Normand, et al.. Adipose cell size and distribution in familial lipoprotein lipase deficiency.. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1992, 16 (10), pp.737-44. ⟨hal-02160233⟩
- M. Bergeron, Thierry Normand, Aoife Bharucha, M Ven Murthy, P Julien, et al.. Prevalence, geographical distribution and genealogical investigations of mutation 188 of lipoprotein lipase gene in the French Canadian population of Québec.. Clinical Genetics, 1992, 41 (4), pp.206-10. ⟨10.1111/j.1399-0004.1992.tb03664.x⟩. ⟨hal-02160230⟩
- Thierry Normand, J. Bergeron, Teresa Fernandez-Margallo, Aoife Bharucha, R Ven Murthy, et al.. Geographic distribution and genealogy of mutation 207 of the lipoprotein lipase gene in the French Canadian population of Québec.. Human Genetics, 1992, 89 (6), pp.671-5. ⟨10.1007/BF00221960⟩. ⟨hal-02160222⟩
- Y. Ma, Howard Henderson, V Murthy, Ghislaine Roederer, M. Monsalve, et al.. A Mutation in the Human Lipoprotein Lipase Gene as the Most Common Cause of Familial Chylomicronemia in French Canadians. New England Journal of Medicine, 1991, 324 (25), pp.1761-1766. ⟨10.1056/NEJM199106203242502⟩. ⟨hal-02160241⟩
- Thierry Normand, Christiane Jean-Faucher, Claude Jean. Neonatal exposure to oestrogens alters the protein profiles and gene expression in the genital tract of adult male mice. Journal of Steroid Biochemistry, 1990, 36 (5), pp.415-423. ⟨10.1016/0022-4731(90)90082-4⟩. ⟨hal-02160254⟩
- Thierry Normand, C. Jean-Faucher, C Jean. Developmental pattern of androgen-regulated proteins in seminal vesicles from the mouse.. International Journal of Andrology, 1989, 12 (3), pp.219-30. ⟨hal-02160364⟩
Communication dans un congrès4 documents
- S. El Haddad, A. Serrano, Thierry Normand, Fabienne Brulé-Morabito, L. Mollet, et al.. Cytogaligin, an additional link between Parkinson’s disease and autophagy pathways?. 7e Congrès du CFATG, Nov 2017, Paris, France. ⟨hal-02934905⟩
- A Serrano, T Guery, S El Haddad, M Dubois, M Schoenwald, et al.. GALIG, gène inducteur de la mort cellulaire, s’exprime au cours de la différenciation myéloïde. 10es Journées du Cancéropole Grand Ouest, Jun 2016, Les Sables d'Olonne, France. ⟨hal-03661932⟩
- S El Haddad, A Serrano, C Ozsancak, P. Auzou, F Moal, et al.. Genes de l’autophagie : marqueurs sanguins potentiels de la maladie de Parkinson. Journées de Neurologie de Langue Française, Apr 2016, Nantes, France. ⟨hal-03661930⟩
- A. Serrano, Thierry Normand, S. El Haddad, M. Dubois, Stéphane Charpentier, et al.. During efficient Anti-RetroViral (ARV) therapy, the expression of GALIG and its interacting partners involved in macroautophagy are deregulated. 6es Journées Scientifiques du CFATG, Oct 2016, Bordeaux, France. ⟨hal-02934903⟩