RAHMOUNI Rachid

email : rachid.rahmouni@cnrs-orleans.fr

Phone : +33 2.38.25.76.08

Office D205

Research director, co-leader of the thematic group “RNA biology and RNA therapeutics

 



43 documents

Article dans une revue

  • Kévin Moreau, Aurélia Le Dantec, Christine Mosrin-Huaman, Yves Bigot, Benoit Piegu, et al.. Perturbation of mRNP biogenesis reveals a dynamic landscape of the Rrp6-dependent surveillance machinery trafficking along the yeast genome. RNA Biology, Taylor & Francis, 2019, pp.1-11. ⟨10.1080/15476286.2019.1593745⟩. ⟨hal-02117640⟩
  • Kévin Moreau, Justine Surand, Aurélia Le Dantec, Christine Mosrin-Huaman, Alain Legrand, et al.. Recombinant yeast and human cells as screening tools to search for antibacterial agents targeting the transcription termination factor Rho. Journal of Antibiotics, Nature Publishing Group: Open Access Hybrid Model Option B, 2018, 71 (4), pp.447-455. ⟨hal-01966171⟩
  • Christine Mosrin-Huaman, Nadège Hervouet-Coste, A. Rachid Rahmouni. Co-transcriptional degradation by the 5′-3′ exonuclease Rat1p mediates quality control of HXK1 mRNP biogenesis in S. cerevisiae. RNA Biology, Taylor & Francis, 2016, 13 (6), pp.582 - 592. ⟨10.1080/15476286.2016.1181255⟩. ⟨hal-01407513⟩
  • Rachid A. Rahmouni, Christine Mosrin-Huaman. In Situ Footprinting of E. coli Transcription Elongation Complex with Chloroacetaldehyde. Methods in Molecular Biology, Humana Press/Springer Imprint, 2015, Methods in Molecular Biology, 1276, pp.229-240. ⟨10.1007/978-1-4939-2392-2_13⟩. ⟨hal-01171857⟩
  • Christine Mosrin-Huaman, Nadege Hervouet-Coste, Aurélia Le Dantec, Igor Stuparevic, A. Rachid Rahmouni. Bacterial Rho helicase: a new tool to dissect mRNP biogenesis and quality control in yeast. Trends in cell and molecular biology, Research Trends, 2014, 9, pp.79 - 93. ⟨hal-01179495⟩
  • Igor Stuparevic, Christine Mosrin-Huaman, Nadège Hervouet-Coste, Mateja Remenaric, A. Rachid Rahmouni. Co-transcriptional recruitment of the RNA exosome cofactors Rrp47p, Mpp6p and two distinct TRAMP complexes assists the exonuclease Rrp6p in the targeting and degradation of an aberrant mRNP in yeast. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2013, ⟨10.1074/jbc.M113.491290⟩. ⟨hal-00874892⟩
  • Romy Honorine, Christine Mosrin-Huaman, Nadege Hervouet-Coste, Domenico Libri, Rachid A. Rahmouni. Nuclear mRNA quality control in yeast is mediated by Nrd1 co-transcriptional recruitment, as revealed by the targeting of Rho-induced aberrant transcripts. Nucleic Acids Research, Oxford University Press, 2011, 39 (7), pp.2809-2820. ⟨10.1093/nar/gkq1192⟩. ⟨hal-00602376⟩
  • Makhlouf Rabhi, Olivier Espéli, Annie Schwartz, Bastien Cayrol, a Rachid Rahmouni, et al.. The Sm-like RNA chaperone Hfq mediates transcription antitermination at Rho-dependent terminators.. EMBO Journal, EMBO Press, 2011, 30 (14), pp.2805-16. ⟨10.1038/emboj.2011.192⟩. ⟨hal-00720713⟩
  • Sergey Proshkin, A. Rachid Rahmouni, Alexander Mironov, Evgeny Nudler. Cooperation between Translating Ribosomes and RNA Polymerase in Transcription. Science, American Association for the Advancement of Science, 2010, 328 (5977), pp.504-508. ⟨10.1126/science.1184939⟩. ⟨hal-00529391⟩
  • Christine Mosrin-Huaman, Romy Honorine, A. Rachid Rahmouni. Expression of Bacterial Rho Factor in Yeast Identifies New Factors Involved in the Functional Interplay between Transcription and mRNP Biogenesis. Molecular and Cellular Biology, American Society for Microbiology, 2009, 29 (15), pp.4033-4044. ⟨10.1128/MCB.00272-09⟩. ⟨hal-00525149⟩
  • Annie Schwartz, Makhlouf Rabhi, Frederique Jacquinot, Emmanuel Margeat, A. Rachid Rahmouni, et al.. A stepwise 2 '-hydroxyl activation mechanism for the bacterial transcription termination factor Rho helicase. Nature Structural and Molecular Biology, Nature Publishing Group, 2009, 16 (12), pp.1309-1316. ⟨10.1038/nsmb.1711⟩. ⟨hal-00525325⟩
  • Annie Schwartz, Céline Walmacq, A. Rachid Rahmouni, Marc Boudvillain. Noncanonical Interactions in the Management of RNA Structural Blocks by the Transcription Termination Rho Helicase. Biochemistry, American Chemical Society, 2007, 46 (33), pp.9366 - 9379. ⟨10.1021/bi700493m⟩. ⟨hal-00166551⟩
  • Annie Schwartz, Emmanuel Margeat, A. Rachid Rahmouni, Marc Boudvillain. Transcription termination factor Rho can displace streptavidin from biotinylated RNA. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2007, 282 (43), pp.31469-31476. ⟨10.1074/jbc.M706935200⟩. ⟨hal-00176284⟩
  • V. Nagarajavel, S. Madhusudan, S. Dole, Ar. Rahmouni, K. Schnetz. Repression by binding of H-NS within the transcription unit. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2007, 282, pp.23622-23630. ⟨hal-00282443⟩
  • C. Walmacq, A.R. Rahmouni, M. Boudvillain. Testing the steric exclusion model for hexameric helicases: substrate features that alter RNA-DNA unwinding by the transcription termination factor Rho. Biochemistry, American Chemical Society, 2006, 45, pp.5885-5895. ⟨10.1021/bi0600648⟩. ⟨hal-00088941⟩
  • L. Moulin, A.R. Rahmouni, F. Boccard. Topological insulators inhibit diffusion of transcription-induced positive supercoils in the chromosome of Escherichia coli. Molecular Microbiology, Wiley, 2005, 55, pp.601-610. ⟨hal-00088662⟩
  • F. ToulmÉ, C. Mosrin-Huaman, I. Artsimovitch, A.R. Rahmouni. Transcriptional pausing in vivo: a nascent RNA hairpin restricts lateral movements of RNA polymerase in both forward and reverse directions. Journal of Molecular Biology, Elsevier, 2005, 351, pp.39-51. ⟨hal-00088714⟩
  • C. Mosrin-Huaman, C.L. Turnbough, A.R. Rahmouni. Translocation of Escherichia coli RNA polymerase against a protein roadblock in vivo highlights a passive sliding mechanism for transcript elongation. Molecular Microbiology, Wiley, 2004, 51, pp.1471-1481. ⟨hal-00113075⟩
  • E. Vieu, Rahmouni A.R.. Dual role of boxB RNA motif in the mechanisms of termination/antitermination at the lambda tR1 terminator revealed in vivo. Journal of Molecular Biology, Elsevier, 2004, 339, pp.1077-1087. ⟨hal-00113087⟩
  • C. Walmacq, A.R. Rahmouni, M. Boudvillain. Influence of substrate composition on the helicase activity of transcription termination factor Rho: reduced processivity of Rho hexamers during unwinding of RNA-DNA hybrid regions. Journal of Molecular Biology, Elsevier, 2004, 342 (2), pp.403-420. ⟨10.1016/j.jmb.2004.07.026⟩. ⟨hal-00113090⟩
  • V. Epshtein, F. ToulmÉ, A.R. Rahmouni, S. Borukhov, E. Nudler. Transcription through the roadblocks: the role of RNA polymerase cooperation. EMBO Journal, EMBO Press, 2003, 22, pp.4719-4727. ⟨hal-00088176⟩
  • A. Schwartz, A. Rachid Rahmouni, Marc Boudvillain. The functional anatomy of an intrinsic transcription terminator. EMBO Journal, EMBO Press, 2003, 22 (13), pp.3385 - 3394. ⟨10.1093/emboj/cdg310⟩. ⟨hal-01880611⟩
  • Marc Boudvillain, Annie Schwartz, A. Rachid Rahmouni. Limited Topological Alteration of the T7 RNA Polymerase Active Center at Intrinsic Termination Sites †. Biochemistry, American Chemical Society, 2002, 41 (9), pp.3137-3146. ⟨10.1021/bi011358q⟩. ⟨hal-02075291⟩
  • F Toulmé, M Mosrin-Huaman, J Sparkowski, A. Das, M. Leng, et al.. GreA and GreB proteins revive backtracked RNA polymerase in vivo by promoting transcript trimming. EMBO Journal, EMBO Press, 2000, 19 (24), pp.6853-6859. ⟨10.1093/emboj/19.24.6853⟩. ⟨hal-02127250⟩
  • F. ToulmÉ, M Guérin, N. Robichon, M. Leng, A. Rachid Rahmouni. In vivo evidence for back and forth oscillations of the transcription elongation complex. EMBO Journal, EMBO Press, 1999, 18 (18), pp.5052-5060. ⟨10.1093/emboj/18.18.5052⟩. ⟨hal-02127238⟩
  • M Guerin, N. Robichon, J. Geiselmann, A. Rachid Rahmouni. A simple polypyrimidine repeat acts as an artificial Rho-dependent terminator in vivo and in vitro. Nucleic Acids Research, Oxford University Press, 1998, 26 (21), pp.4895-4900. ⟨10.1093/nar/26.21.4895⟩. ⟨hal-02127232⟩
  • N. Figueroa-Bossi, M Guérin, A. Rachid Rahmouni, M Leng, L Bossi. The supercoiling sensitivity of a bacterial tRNA promoter parallels its responsiveness to stringent control. EMBO Journal, EMBO Press, 1998, 17 (8), pp.2359-2367. ⟨10.1093/emboj/17.8.2359⟩. ⟨hal-02127234⟩
  • A. Albert, F Spirito, N Bossi, L Bossi, A. Rachid Rahmouni. Hyper-negative template DNA supercoiling during transcription of the tetracycline-resistance gene in topA mutants is largely constrained in vivo. Nucleic Acids Research, Oxford University Press, 1996, 24 (15), pp.3093-3099. ⟨10.1093/nar/24.15.3093⟩. ⟨hal-02127221⟩
  • M Guérin, M. Leng, A. Rachid Rahmouni. High resolution mapping of E.coli transcription elongation complex in situ reveals protein interactions with the non-transcribed strand.. EMBO Journal, EMBO Press, 1996, 15 (19), pp.5397-5407. ⟨hal-02127225⟩
  • Annie-Claude Albert, Marc Leng, A. Rachid Rahmouni. The Size of the Topological Domain Modulates the B-Z Transition of a (TG) n Containing Repeat. Journal of Biomolecular Structure and Dynamics, Taylor & Francis: STM, Behavioural Science and Public Health Titles, 1995, 13 (1), pp.47-56. ⟨10.1080/07391102.1995.10508820⟩. ⟨hal-02127217⟩
  • A.C Albert, A. Roman, G. Bouche, M. Leng, A. Rachid Rahmouni. Gradual and oriented B-Z transition in 5'-untranscribed region of mouse ribosomal DNA.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1994, 269 (30), pp.19238-44. ⟨hal-02127210⟩
  • Laurence Tartier, Veslav Michalik, Melanie Spotheim-Maurizot, A. Rachid Rahmouni, Roland Sabattier, et al.. Radiolytic signature of Z-DNA. Nucleic Acids Research, Oxford University Press, 1994, 22 (25), pp.5565-5570. ⟨10.1093/nar/22.25.5565⟩. ⟨hal-02127214⟩
  • A. Rachid Rahmouni. Z-DNA as a probe for localized supercoiling in vivo. Molecular Microbiology, Wiley, 1992, 6 (5), pp.569-572. ⟨10.1111/j.1365-2958.1992.tb01502.x⟩. ⟨hal-02127207⟩
  • A. Rachid Rahmouni, R Wells. Direct evidence for the effect of transcription on local DNA supercoiling in vivo.. Journal of Molecular Biology, Elsevier, 1992, 223 (1), pp.131-44. ⟨hal-02127204⟩
  • M. Lemaire, A. Rachid Rahmouni, A. Schwartz, M. Leng. Interstrand cross-links are preferentially formed at the d(GC) sites in the reaction between cis-diamminedichloroplatinum (II) and DNA.. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 1991, 88 (5), pp.1982-1985. ⟨10.1073/pnas.88.5.1982⟩. ⟨hal-02127202⟩
  • R Rajagopalan, A. Rachid Rahmouni, R Wells. Flanking AT-rich tracts cause a structural distortion in Z-DNA in plasmids.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1990, 265 (28), pp.17294-9. ⟨hal-02127194⟩
  • K Mazeau, F. Vovelle, A. Rachid Rahmouni, M. Leng, M. Ptak. Structure of the intrastrand cis-[Pt(NH3)2(d(GpCpG))] adduct in a dodecanucleotide duplex: II. A molecular mechanics modeling study.. Anti-Cancer Drug Design, 1989, 4 (1), pp.63-78. ⟨hal-02127180⟩
  • M. Ptak, A. Rachid Rahmouni, K Mazeau, N Thuong, M. Leng. Structure of the intrastrand cis-[Pt(NH3)2(d(GpCpG))] adduct in a dodecanucleotide duplex: I. A 1H and 31P n.m.r. study.. Anti-Cancer Drug Design, 1989, 4 (1), pp.53-61. ⟨hal-02127173⟩
  • A. Rachid Rahmouni, R Wells. Stabilization of Z DNA in vivo by localized supercoiling.. Science, American Association for the Advancement of Science, 1989, 246 (4928), pp.358-63. ⟨hal-02127190⟩
  • A. Rachid Rahmouni, M. Leng. Reaction of nucleic acids with cis-diamminedichloroplatinum(II): interstrand cross-links.. Biochemistry, American Chemical Society, 1987, 26 (23), pp.7229-34. ⟨hal-02127140⟩
  • A. Rachid Rahmouni, Jean-Marc Malinge, Annie Schwartz, Marc Leng. Comparison Between poly(dG-dC)·poly(dG-dC) and DNA Modified by cis-diamminedichloroplatinum (II): Immunological and Spectroscopic Studies. Journal of Biomolecular Structure and Dynamics, Taylor & Francis: STM, Behavioural Science and Public Health Titles, 1985, 3 (2), pp.363-375. ⟨10.1080/07391102.1985.10508423⟩. ⟨hal-02127084⟩

Chapitre d'ouvrage

  • Makhlouf Rabhi, Rahmouni Rachid A., Marc Boudvillain. Transcription termination factor Rho: a ring-shaped RNA helicase from bacteria. Eckhard Jankowsky. RNA helicases, Royal Society of Chemistry Publishing, pp.243-271, 2010, ⟨10.1039/9781849732215-00243⟩. ⟨hal-00610004⟩
  • A. Rachid Rahmouni, A. Schwartz, M. Leng. Importance of DNA Sequence in the Reaction of d(ApG) and d(GpA) with Cis-Diamminedichloroplatinum (II). Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy: Proceedings of the Fifth International Symposium on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy Abano, Padua, ITALY - June 29–July 2, 1987, Springer US, pp.127-131, 1988. ⟨hal-02127164⟩

 

RIDOU Loïck

email : loick.ridou@cnrs-orleans.fr

Phone : +33 2.38.25.55.75

Office A102b

Assistant engineer within the  thematic groupe “Skin Biology”

 



14 documents

Article dans une revue

  • Giovanni Busco, Azadeh Valinataj Omran, Loick Ridou, Jean-Michel Pouvesle, Eric Robert, et al.. Cold atmospheric plasma-induced acidification of tissue surface: visualization and quantification using agarose gel models. Journal of Physics D: Applied Physics, IOP Publishing, 2019, 52 (24), pp.24LT01. ⟨10.1088/1361-6463/ab1119⟩. ⟨hal-02089383⟩
  • Giovanni Busco, Fabienne Fasani, Sébastien Dozias, Loick Ridou, Claire Douat, et al.. Changes in Oxygen Level Upon Cold Plasma Treatments: Consequences for RONS Production. IEEE Transactions on Radiation and Plasma Medical Sciences, IEEE, 2018, 2 (2), pp.147 - 152. ⟨10.1109/TRPMS.2017.2775705⟩. ⟨hal-01803848⟩

Communication dans un congrès

  • Giovanni Busco, Loick Ridou, Fabienne Fasani, Sébastien Dozias, Jean-Michel Pouvesle, et al.. Investigation on a He-Plasma Gun source for cosmetic purposes: the importance of skin microenvironment. ICPM7, ISPM, Jun 2018, Philadelphia, United States. ⟨hal-01943058⟩
  • Giovanni Busco, Fabienne Fasani, Sébastien Dozias, Loick Ridou, Claire Douat, et al.. Importance de la pression partielle d’oxygène lors des traitements par le plasma froid. Journées du GDR ABioPlas, GDR ABioPlas, Oct 2017, Paris, France. ⟨hal-01945949⟩
  • Eric Robert, Xavier Damany, Sylvain Iséni, Marc Vandamme, Sébastien Dozias, et al.. Bio environmental applications of plasmas . Frontiers in Plasma Science 2, Feb 2016, Greifswald, Germany. ⟨hal-01344069⟩
  • Jean-Michel Pouvesle, Guillaume Collet, Eric Robert, Loick Ridou, Laura Brullé, et al.. Potential of plasma based soft and/or combined cancer treatments. 22nd International Symposium on Plasma Chemistry ISPC 22, IPCS, Jul 2015, Antwerp, Belgium. ⟨hal-01254779⟩
  • Jean-Michel Pouvesle, Guillaume Collet, Eric Robert, Loick Ridou, Sébastien Dozias, et al.. Potential of low temperature plasma sources in cancer treatment. AVS 62nd International Symposium, AVS, Oct 2015, San José, United States. ⟨hal-01258294⟩
  • Jean-Michel Pouvesle, Guillaume Collet, Eric Robert, Loick Ridou, Sébastien Dozias, et al.. POTENTIAL OF PLASMA BASED SOFT AND/OR COMBINED CANCER TREATMENTS. COST MP1101 Workshop 2015, University of Ankara, COST MP1101, May 2015, Istanbul, Turkey. ⟨hal-01163664⟩
  • Jean-Michel Pouvesle, Guillaume Collet, Eric Robert, Loick Ridou, Sebatien Dozias, et al.. Potential of plasma based soft and/or combined cancer treatments. IWPCT 2, M. Hori, Nogoya University, Mar 2015, Nagoya, Japan. ⟨hal-01148938⟩
  • Eric Robert, Thibault Darny, Sylvain Iseni, Marc Vandamme, Sébastien Dozias, et al.. Physics and biomedical applications of plasma jets. 3rd RAPID Symposium, Oct 2015, Perpignan, France. ⟨hal-01258136⟩
  • Jean-Michel Pouvesle, Eric Robert, Laura Brullé, Guillaume Collet, Thibault Darny, et al.. ANTITUMOR EFFECT OF LOW TEMPERATURE NON THERMAL PLASMAS: TOWARDS “SOFT” TREATMENTS . ISPB 2014, Aug 2014, Sokcho, South Korea. ⟨hal-01147159⟩
  • Jean-Michel Pouvesle, Guillaume Collet, Eric Robert, Marc Vandamme, Loick Ridou, et al.. In vivo tissue oxygenation triggered through Plasma Gun treatment. ICPM5, ISPM, May 2014, Nara, Japan. ⟨hal-01149233⟩

Poster

  • Giovanni Busco, Azadeh Valinataj Omran, Loick Ridou, Jean-Michel Pouvesle, Eric Robert, et al.. Fluorescein-agarose gel as a tissue model to visualize and measure local CAP-induced acidification. 24th International Symposium on Plasma Chemistry (ISPC24), Jun 2019, Naples, Italy. ⟨hal-02263357⟩
  • Guillaume Collet, Loick Ridou, Eric Robert, Marc Vandamme, Thibault Darny, et al.. NTP antitumor soft treatment: evidence of a triggering effect?. ICPM5, May 2014, Nara, Japan. ⟨hal-01151380⟩

REVERCHON – ASSADI Flora

 

email : flora.reverchon@cnrs-orleans.fr

Phone : +33 2.38.25.55.75

Researcher Postdoc within the team “Cell Biology, Molecular Targets and Innovative Therapies”
 



2 documents

Article dans une revue

  • Chayma El Khamlichi, Flora Reverchon-Assadi, Nadège Hervouet-Coste, Lauren Blot, Eric Reiter, et al.. Bioluminescence Resonance Energy Transfer as a Method to Study Protein-Protein Interactions: Application to G Protein Coupled Receptor Biology. Molecules, MDPI, 2019, 24 (3), pp.537. ⟨10.3390/molecules24030537⟩. ⟨hal-02067271⟩
  • Flora Reverchon, Stéphane Mortaud, Maëliss Sivoyon, Isabelle Maillet, Anthony Laugeray, et al.. IL-33 receptor ST2 regulates the cognitive impairments associated with experimental cerebral malaria. PLoS Pathogens, Public Library of Science, 2017, 13 (4), ⟨10.1371/journal.ppat.1006322⟩. ⟨hal-01656488⟩

ROBIN Chloé

email : chloe.robin@cnrs-orleans.fr

Phone : +33 2.38.25.55.86

Office A113

Assistant engineer in biology, Natural sciences within the thematic group “Cell Signaling”

 



7 documents

Article dans une revue

  • Anamarija Jurisic, Chloé Robin, Pavel Tarlykov, Lee Siggens, Brigitte Schoell, et al.. Topokaryotyping demonstrates single cell variability and stress dependent variations in nuclear envelope associated domains. Nucleic Acids Research, Oxford University Press, 2018, 46 (22), pp.e135. ⟨10.1093/nar/gky818⟩. ⟨hal-02159521⟩
  • Saïd El Haddad, Amandine Serrano, Thierry Normand, Chloé Robin, Martine Dubois, et al.. Interaction of Alpha-synuclein with Cytogaligin, a protein encoded by the proapoptotic gene GALIG. Biochemical and Biophysical Research Communications, Elsevier, 2018, 495 (1), pp.787-792. ⟨10.1016/j.bbrc.2017.11.078⟩. ⟨hal-01966108⟩
  • Amandine Serrano, Saïd El Haddad, Fréderic Moal, Thierry Prazuck, Eric Legac, et al.. Dysregulation of apoptosis and autophagy gene expression in peripheral blood mononuclear cells of efficiently treated HIV-infected patients. AIDS, Lippincott, Williams & Wilkins, 2018, 32 (12), pp.1579 - 1587. ⟨10.1097/QAD.0000000000001851⟩. ⟨hal-01936094⟩
  • Diego Germini, Yara Bou Saada, Tatiana Tsfasman, Kristina Osina, Chloé Robin, et al.. A One-Step PCR-Based Assay to Evaluate the Efficiency and Precision of Genomic DNA-Editing Tools. Molecular Therapy - Methods & Clinical Development, 2017, 5, pp.43-50. ⟨10.1016/j.omtm.2017.03.001⟩. ⟨hal-02159956⟩
  • A. Jurisic, Chloé Robin, V. Ogryzko. Topokaryotyping – a proposal for a novel approach to study nuclear organization. Biopolymers and Cell, 2015, 31 (1), pp.72-79. ⟨10.7124/bc.0008CF⟩. ⟨hal-02159965⟩
  • Muhammad Shoaib, Arman Kulyyassov, Chloé Robin, Kinga Winczura, Pavel Tarlykov, et al.. PUB-NChIP--"in vivo biotinylation" approach to study chromatin in proximity to a protein of interest. Genome Research, Cold Spring Harbor Laboratory Press, 2013, 23 (2), pp.331-340. ⟨10.1101/gr.134874.111⟩. ⟨hal-02159970⟩
  • Elena Ioudinkova, Ana Barat, Andrey Pichugin, Elena Markova, Ilya Sklyar, et al.. Distinct Distribution of Ectopically Expressed Histone Variants H2A.Bbd and MacroH2A in Open and Closed Chromatin Domains. PLoS ONE, Public Library of Science, 2012, 7 (10), pp.e47157. ⟨10.1371/journal.pone.0047157⟩. ⟨hal-02159968⟩

 

NORMAND Thierry

 

email : thierry.normand@cnrs-orleans.fr

Phone : +33 2.38.25.55.86

Office A113

Lecturer within the thematic group “Cell Signaling”

 



21 documents

Article dans une revue

  • Saïd El Haddad, Amandine Serrano, Thierry Normand, Chloé Robin, Martine Dubois, et al.. Interaction of Alpha-synuclein with Cytogaligin, a protein encoded by the proapoptotic gene GALIG. Biochemical and Biophysical Research Communications, Elsevier, 2018, 495 (1), pp.787-792. ⟨10.1016/j.bbrc.2017.11.078⟩. ⟨hal-01966108⟩
  • Amandine Serrano, Saïd El Haddad, Fréderic Moal, Thierry Prazuck, Eric Legac, et al.. Dysregulation of apoptosis and autophagy gene expression in peripheral blood mononuclear cells of efficiently treated HIV-infected patients. AIDS, Lippincott, Williams & Wilkins, 2018, 32 (12), pp.1579 - 1587. ⟨10.1097/QAD.0000000000001851⟩. ⟨hal-01936094⟩
  • Lucile Mollet, Pauline Robinet, Martine Dubois, Axel Aurouet, Thierry Normand, et al.. Opposing Mcl-1, the GALIG proapoptotic gene is upregulated as neutrophils die and underexpressed in Acute Myeloid Leukemia cells.. Molecular Immunology, Elsevier, 2013, 56 (1-2), pp.123-8. ⟨10.1016/j.molimm.2013.04.012⟩. ⟨hal-00840170⟩
  • Pauline Robinet, Lucile Mollet, Patrick Gonzalez, Thierry Normand, Stephane Charpentier, et al.. The mitogaligin protein is addressed to the nucleus via a non-classical localization signal. Biochemical and Biophysical Research Communications, Elsevier, 2010, 392 (1), pp.53-57. ⟨10.1016/j.bbrc.2009.12.162⟩. ⟨hal-00529397⟩
  • Alexis D. Sennepin, Stéphane Charpentier, Thierry Normand, Cedric Sarre, Alain Legrand, et al.. Multiple reprobing of Western blots after inactivation of peroxidase activity by its substrate, hydrogen peroxide. Analytical Biochemistry, Elsevier Masson, 2009, 393 (1), pp.129-131. ⟨10.1016/j.ab.2009.06.004⟩. ⟨hal-00525339⟩
  • Patrick Gonzalez, Pauline Robinet, Stéphane Charpentier, Lucile Mollet, Thierry Normand, et al.. Apoptotic activity of a nuclear form of mitogaligin, a cell death protein. Biochemical and Biophysical Research Communications, Elsevier, 2009, 378 (4), pp.816-820. ⟨10.1016/j.bbrc.2008.11.133⟩. ⟨hal-00522444⟩
  • Patrick Gonzalez, Mélanie Duneau, Stéphane Charpentier, Thierry Normand, Lucile Mollet, et al.. Destabilization of Membranes Containing Cardiolipin or Its Precursors by Peptides Derived from Mitogaligin, a Cell Death Protein. Biochemistry, American Chemical Society, 2007, 46 (25), pp.7374-7382. ⟨10.1021/bi700213p⟩. ⟨hal-00159568⟩
  • M. Duneau, M. Boyer Guittaut, P. Gonzalez, S. Charpentier, T. Normand, et al.. Galig, a novel cell death gene that encodes a mitochondrial protein promoting cytochrome c release. Experimental Cell Research, Elsevier, 2005, 302, pp.194-205. ⟨hal-00088588⟩
  • Michaël Guittaut, Stéphane Charpentier, Thierry Normand, Martine Dubois, Jacques Raimond, et al.. Identification of an Internal Gene to the Human Galectin-3 Gene with Two Different Overlapping Reading Frames That Do Not Encode Galectin-3. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2001, 276 (4), pp.2652-2657. ⟨10.1074/jbc.m002523200⟩. ⟨hal-02137994⟩
  • J. Morissette, F. Durocher, J. Leblanc, T. Normand, F. Labrie, et al.. Genetic linkage mapping of the human steroid 5α-reductase type 2 gene (SRD5A2) close to D2S352 on chromosome region 2p23→p22. Cytogenetic and Genome Research, Karger, 1996, 73 (4), pp.304-307. ⟨10.1159/000134362⟩. ⟨hal-02160041⟩
  • Thierry Normand, B. Husen, F Leenders, H Pelczar, J.L Baert, et al.. Molecular characterization of mouse 17 beta-hydroxysteroid dehydrogenase IV.. Journal of Steroid Biochemistry and Molecular Biology, Elsevier, 1995, 55 (5-6), pp.541-8. ⟨10.1016/0960-0760(95)00204-9⟩. ⟨hal-02160020⟩
  • A.M. Simon, C. Guilbault, Thierry Normand, Christiane Jean-Faucher, Georges Veyssière, et al.. Developmental and hormonal regulation of specific proteins in mouse seminal vesicles. Isolation and characterization of genomic and cDNA clones for androgen-regulated secretory protein. Experimental and Clinical Endocrinology, 1995, 14, pp.73-82. ⟨hal-02167152⟩
  • J Adamski, Thierry Normand, F Leenders, D Monté, A. Bégué, et al.. Molecular cloning of a novel widely expressed human 80 kDa 17 β -hydroxysteroid dehydrogenase IV. Biochemical Journal, Portland Press, 1995, 311 (2), pp.437-443. ⟨10.1042/bj3110437⟩. ⟨hal-02160026⟩
  • J Simard, Jean Feunteun, Gilbert Lenoir, T Tonin, Thierry Normand, et al.. Genetic mapping of the breast-ovarian cancer syndrome to a small interval on chromosome 17q12–21: exclusion of candidate genes EDH17B2 and RARA. Human Molecular Genetics, Oxford University Press (OUP), 1993, 2 (8), pp.1193-1199. ⟨10.1093/hmg/2.8.1193⟩. ⟨hal-02160208⟩
  • Thierry Normand, Steven Narod, Fernand Labrie, Jacques Simard. Detection of polymorphisms in the estradiol 17β-hydroxysteroid dehydrogenase II gene at the EDH17B2 locus on 17q11–q21. Human Molecular Genetics, Oxford University Press (OUP), 1993, 2 (4), pp.479-483. ⟨10.1093/hmg/2.4.479⟩. ⟨hal-02160210⟩
  • P Peeva, L Brun, M Ven Murthy, P Després, Thierry Normand, et al.. Adipose cell size and distribution in familial lipoprotein lipase deficiency.. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1992, 16 (10), pp.737-44. ⟨hal-02160233⟩
  • M. Bergeron, Thierry Normand, A. Bharucha, M Ven Murthy, P Julien, et al.. Prevalence, geographical distribution and genealogical investigations of mutation 188 of lipoprotein lipase gene in the French Canadian population of Québec.. Clinical Genetics, Wiley, 1992, 41 (4), pp.206-10. ⟨10.1111/j.1399-0004.1992.tb03664.x⟩. ⟨hal-02160230⟩
  • Thierry Normand, J. Bergeron, Teresa Fernandez-Margallo, A. Bharucha, R Ven Murthy, et al.. Geographic distribution and genealogy of mutation 207 of the lipoprotein lipase gene in the French Canadian population of Québec.. Human Genetics, Springer Verlag, 1992, 89 (6), pp.671-5. ⟨10.1007/BF00221960⟩. ⟨hal-02160222⟩
  • Y. Ma, Howard Henderson, V Murthy, Ghislaine Roederer, M. Monsalve, et al.. A Mutation in the Human Lipoprotein Lipase Gene as the Most Common Cause of Familial Chylomicronemia in French Canadians. New England Journal of Medicine, Massachusetts Medical Society, 1991, 324 (25), pp.1761-1766. ⟨10.1056/NEJM199106203242502⟩. ⟨hal-02160241⟩
  • Thierry Normand, Christiane Jean-Faucher, Claude Jean. Neonatal exposure to oestrogens alters the protein profiles and gene expression in the genital tract of adult male mice. Journal of Steroid Biochemistry, Elsevier, 1990, 36 (5), pp.415-423. ⟨10.1016/0022-4731(90)90082-4⟩. ⟨hal-02160254⟩
  • Thierry Normand, C. Jean-Faucher, C Jean. Developmental pattern of androgen-regulated proteins in seminal vesicles from the mouse.. International Journal of Andrology, Wiley, 1989, 12 (3), pp.219-30. ⟨hal-02160364⟩