UPR 4301

Center for Molecular Biophysics, CNRS - Orleans

The Center for Molecular Biophysics (CBM) develops research at the interface of chemistry, biology and physics to study the molecular mechanisms that sustain life or dysfunctions leading to diseases.

Unveiling billion-year old life forms with X-ray vision

Synchrotron-based studies reveal unprecedented details of some of the most ancient traces of life in 3D. Fossilised bacteria 1.9 billion years old were imaged in situ in a fragment of rock by Ptychographic X-rays Computed Tomography documenting details of preservation not previously observed.

Manganese: A double agent for imaging ?

Manganese is a biocompatible metal ion, with great interest for MRI and PET. The alliance between Mn2+ and a bispidine ligand leads to an unprecedented kinetic inertness, which might enable its in vivo use without any toxicity risk.