UPR 4301
Center for Molecular Biophysics, CNRS - Orleans
The Center for Molecular Biophysics (CBM) develops research at the interface of chemistry, biology and physics to study the molecular mechanisms that sustain life or dysfunctions leading to diseases.
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Creation of a predictive model of metabolic changes characteristic of neurodegenerative diseases
Researchers have created a predictive model based on the detection of changes in metabolite concentration resolved by ¹H high-resolution MAS NMR
Achille Le Bel Grand Prize awarded to Eva Jakab Toth
The Achille Le Bel Grand Prize, awarded by the Société Chimique de France, rewards internationally recognized works.
Disturbed expression of autophagy genes in blood of Parkinson's disease patients
A dysregulation in the expression of autophagy genes necessary for the elimination of neurotoxic protein aggregates, observed in Parkinson's disease, is also directly detectable in the blood of patients
Unveiling billion-year old life forms with X-ray vision
Synchrotron-based studies reveal unprecedented details of some of the most ancient traces of life in 3D. Fossilised bacteria 1.9 billion years old were imaged in situ in a fragment of rock by Ptychographic X-rays Computed Tomography documenting details of preservation not previously observed.
Organometallic networks for the near-infrared emission of lanthanides
A new approach to sensitize the near-infrared luminescence of lanthanides based on the use of the cavity of organometallic networks
Manganese: A double agent for imaging ?
Manganese is a biocompatible metal ion, with great interest for MRI and PET. The alliance between Mn2+ and a bispidine ligand leads to an unprecedented kinetic inertness, which might enable its in vivo use without any toxicity risk.