Find here all the news from the CBM and beyond
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"Structural insights into atypical cell-penetration properties of Homeoproteins"
Since 1990 75% of insects have disappeared in Europe.
"Structural insights of lipid droplets using large scale instrument approaches".
The CNRS Institute of Chemistry reports on its website a publication by CBM researchers published in the journal Nucleic Acids Research. The researchers used "AlphaFold 2", an artificial intelligence tool, to predict and describe the structure of PARP proteins in order to better understand their functionalities. PARP proteins are potential targets for new cancer treatments.
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Meetings in the fields of Life Sciences, Health and Well-being in the Centre - Val de Loire region
"The microRNA miR-30a plays a key role in human chronological skin aging by regulating cell differentiation, cell death and autophagy".
The development of a new epidermis model that respects the skin oxygen physiological level of oxygen by CBM researchers has highlighted the role of oxygen in the expression and activity of antioxidant enzymes, which are essential for slowing skin ageing.
The new study focussed on the process known as SUMOylation, an essential biological regulatory mechanism, inaugurates the "SUMOwriteNread" project funded by the European Research Council, which aims to crack secrets of SUMOylation.
"mRNPs biogenesis perturbation by the bacterial Rho factor : genomic analysis of the recrutment of the THO complex and its subunits".
"Direct structural/functional characterization of therapeutically relevant membrane protein complexes and soluble oligomers by NALIM (Native Liquid MALDI) - TOF MS, an original Mass Spectrometry approach".
A collaborative study co-led by the CBM researcher, Marcin J. Suskiewicz, combines structural prediction with the AI-powered tool AlphaFold2 with experiments to gain deeper understanding of an important group of proteins, the PARP family.
Contribution of HPF1 to cellular response to cancer-relevant PARP inhibitors via the modulation of PARP1 trapping at DNA lesions
3 researchers from the NMNS "NanoMedicines and NanoProbes" laboratory in Tours will present their research work.
Le Studium Experts Days "Cell state transitions and plasticity at the interface of inflammation and pre-neoplasia in mouse, human, and organoids"