email : guillaume.gabant[remplacer_par_at]cnrs-orleans.fr
Téléphone : 02.38.25.54.57
Ingénieur de recherche, responsable de la plateforme “MO2VING”
- Métadonnées
Publications (Archives Hal)
Contact
isabelle.frapart@cnrs-orleans.fr 02.38.25.55.53
Disciplines
- Sciences du Vivant [q-bio]11
- Physique [physics]9
- Chimie/Chimie analytique4
- Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Biochimie [q-bio.BM]4
- Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Biologie structurale [q-bio.BM]4
- Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire4
- Sciences du Vivant [q-bio]/Médecine humaine et pathologie3
- Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Biophysique2
- Chimie1
- Sciences du Vivant [q-bio]/Biologie végétale1
Mots-clefs
ABZ AMC Activity-based probes Agrobacterium Alimentation Alpha-1-proteinase inhibitor Alpha2-M Alpha2-macroglobulin Aminomethyl coumarin COLI COPD CatG Cathepsin G Channel-kinase interaction Chronic obstructive pulmonary disease Design of Experiments Diploid EDDnp ETD Mass spectrometry
- Mass spectrometry3
- ABZ1
- AMC1
- Activity-based probes1
- Agrobacterium1
- Alimentation1
- Alpha-1-proteinase inhibitor1
- Alpha2-M1
- Alpha2-macroglobulin1
- Aminomethyl coumarin1
- COLI1
- COPD1
- CatG1
- Cathepsin G1
- Channel-kinase interaction1
- Chronic obstructive pulmonary disease1
- Design of Experiments1
- Diploid1
- EDDnp1
- ETD1
- FRET1
- Fluorescence resonance energy transfer1
- GPA1
- Genetic transformation1
- Granulomatosis with polyangiitis1
- H1
- HPLC1
- High performance liquid chromatography1
- Human1
- Inflammation1
- Inflammatory diseases1
- Isothermal calorimetry1
- K+ CHANNEL1
- Kinase-substrate structure1
- LASER-DESORPTION IONIZATION1
- LC-MS/MS1
- MALDI TOF mass spectrometry1
- MECHANISM1
- MOLECULAR-BASIS1
- MS1
- Mordenite1
- N-24- dinitrophenylethylenediamine1
- NE1
- NMDA receptor1
- NSP1
- Neutrophil1
- Neutrophil elastase1
- Neutrophil serine proteinase1
- Optimization1
- Origins of Life1
- Ortho- aminobenzoic acid1
- PBS1
- PEPTIDES1
- POTASSIUM CHANNEL1
- PR31
- Phosphate-buffered saline1
- Phosphoribosyl pyrophosphate1
- Protease1
- Protease inhibitor1
- Proteinase 31
- Proteinase 3 myeloblastin1
- Proteolysis1
- RHODOPSIN1
- RNA building blocks1
- Ribonucleotides1
- Rosa1
- Résidus1
- SDHI1
- SDOE1
- SELECTIVITY1
- Serine protease1
- Serine proteinase Abbreviations alpha1-PI1
- Somatic embryogenesis1
- UHR-QTOF1
- X-RAY-STRUCTURE1
Auteurs
Gabant Guillaume16 Cadene Martine15 Gabant G.9 Bijot T.3 Cadène Martine3 Korkmaz Brice3 Schönherr Roland2 Sienczyk Marcin2 Kellenberger Christine2 Armengaud J.2 Boyer A.2 Dedieu Alain2 Gauthier Francis2 Augier Julie1 Bellanger Laurent1 Berteaux Y.1 Bieth Joseph1 Bouchet Nicolas1 Boyer Alain1 Brillet Benjamin1 Briseño-Roa Luis1 Bujnicki Janusz1 Bujnicki M.1 Castro-Rodrigues Artur1 Chaussinand Guylaine1 Chauvet Aurélie1 Clemençon Rudy1 Dallet-Choisy Sandrine1 Debener Thomas1 Derache Chrystelle1 Epinette C.1 Epinette Christophe1 Fernandes Andreia s.1 Fernandez Bernard1 Fonseca Fátima1 Gajda Michal1 Gardênnia da Fonseca Maria1 Gauthier F.1 Glauser Gaëtan1 Grzywa Renata1 Guarino C.1 Guinchard Sylvie1 Heinemann Stefan h.1 Jaillet Jerome1 Jenne D. E.1 Juliano Maria1 Le Mee Marylène1 Legowska M.1 Lesner A.1 Locard Marie1 Lorphelin Alain1 Maene Marion1 Marchetti Charles1 Marques-Carvalho Maria J1 Marques-Carvalho Maria joão1 Mebold E.1 Morais-Cabral João1 Morais-Cabral João H1 Morais-Cabral João henrique1 Motteau S.1 Muskett Frederick W1 Muñoz Eva1 N'Guessan Koffi1 Natkunarajah Sharuja1 Nemcic M.1 Nemcic Matej1 Nozerand Nathalie1 Oppermann Johannes1 Pinetre J.1 Pinêtre Justine1 Quemeneur Eric1 Retif Stéphanie1 Richer Y.1 Rigaud Baptiste1 Robertson Gail1 Rodrigues Francisco1 Sahoo Nirakar1 Seren Seda1 Sobilo Julien1 Stekovic Martin1 Tuszynska Irina1 Vieira-Pires Ricardo S1 Vlahou A.1 Wysocka M.1 Wysocka Magdalena1 Zhao Yaxian1 Zhuang Guanzheng1 Zoidakis J.1 van Dorssaeler Alain1 Roussel Alain1 Vergne Philippe1 Jaber Maguy1 Gaslain Fabrice1 Pasquet Camille1 Kellenberger C.1 Alpha-Bazin Béatrice1 Bendahmane Mohammed1 Même Sandra1 Lacerda S.1 Bonmatin Jean-Marc1
Revues
Institutions
- Université d'Orléans22
- Université de Tours22
- Institut National de la Santé et de la Recherche Médicale22
- Institut de Chimie - CNRS Chimie22
- Commissariat à l'énergie atomique et aux énergies alternatives3
- Aix Marseille Université2
- Instituto de Biologia Molecular e Celular2
- Wroclaw University of Science and Technology2
- Institut National de la Recherche Agronomique2
- Faculty of Chemistry [Univ Gdańsk]1
- Université Claude Bernard Lyon 11
- Université de Strasbourg1
- Université de Haute-Alsace (UHA) Mulhouse - Colmar1
- École Nationale Supérieure d'Ingénieurs de Caen1
- Institut National de Physique Nucléaire et de Physique des Particules du CNRS1
- Université de Brest1
- Université Louis Pasteur - Strasbourg I1
- Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL1
- Université de Neuchâtel = University of Neuchatel1
- University of Leicester1
- Mines Paris - PSL (École nationale supérieure des mines de Paris)1
- Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris1
- Ecole Polytechnique Fédérale de Lausanne1
- Universidade Federal da Paraiba | Federal University of Paraiba1
- Biomedical Research Foundation of the Academy of Athens1
- Jena University Hospital [Jena]1
- Max Planck Institute of Neurobiology1
- University of Wisconsin-Madison1
- University of Wrocław [Poland]1
- Friedrich-Schiller-Universität = Friedrich Schiller University Jena [Jena, Germany]1
- Software 4 Science Developments1
- École normale supérieure - Paris1
- École normale supérieure de Lyon1
- Université de Caen Normandie1
- Université Pierre et Marie Curie - Paris 61
Laboratoires
- Centre de biophysique moléculaire22
- Pathologies Respiratoires : Protéolyse et Aérosolthérapie3
- Laboratoire de Biochimie des Systèmes Perturbés2
- Centre des Matériaux1
- Laboratoire Universitaire de Biodiversité et Ecologie Microbienne1
- Physique et Chimie du Vivant1
- Architecture et fonction des macromolécules biologiques1
- Infection et inflammation. Immunopathologie et enzymologie1
- Laboratoire d'Archéologie Moléculaire et Structurale1
- Biologie Cellulaire de la Synapse Normale et Pathologique1
- Service de Biochimie et Toxicologie Nucléaire1
- Institute of Lung Biology and Disease (iLBD) - Comprehensive Pneumology Center (CPC)1
- Institut de Chimie des Substances Naturelles1
- Laboratoire de chimie bactérienne1
- Institut des matériaux de Paris-Centre1
- Reproduction et développement des plantes1
- Laboratoire catalyse et spectrochimie1
- Institut Pluridisciplinaire Hubert Curien1
Équipes de recherche
25 documents
Article dans une revue15 documents
- Guillaume Gabant, Martin Stekovic, Matej Nemcic, Justine Pinêtre, Martine Cadene. A sDOE (simple design-of-experiment) approach for parameter optimization in mass spectrometry. Part 1. Parameter selection and interference effects in topdown ETD fragmentation of proteins in a UHR-QTOF instrument.. Journal of The American Society for Mass Spectrometry, 2023, 34 (1), pp.27-35. ⟨10.1021/jasms.2c00215⟩. ⟨hal-03871364⟩
- Koffi N'Guessan, Renata Grzywa, Seda Seren, Guillaume Gabant, Maria Juliano, et al.. Human proteinase 3 resistance to inhibition extends to alpha-2 macroglobulin. FEBS Journal, 2020, ⟨10.1111/febs.15229⟩. ⟨hal-02901768⟩
- Francisco Rodrigues, Thomas Georgelin, Guillaume Gabant, Baptiste Rigaud, Fabrice Gaslain, et al.. Confinement and Time Immemorial: Prebiotic Synthesis of Nucleotides on a Porous Mineral Nanoreactor. Journal of Physical Chemistry Letters, 2019, 10 (15), pp.4192-4196. ⟨10.1021/acs.jpclett.9b01448⟩. ⟨hal-02308428⟩
- Artur Castro-Rodrigues, Yaxian Zhao, Fátima Fonseca, Guillaume Gabant, Martine Cadène, et al.. The Interaction between the Drosophila EAG Potassium Channel and the Protein Kinase CaMKII Involves an Extensive Interface at the Active Site of the Kinase. Journal of Molecular Biology, 2018, 430 (24), pp.5029-5049. ⟨10.1016/j.jmb.2018.10.015⟩. ⟨hal-01966024⟩
- Guillaume Gabant, Alain Boyer, Martine Cadene. SSPaQ: A Subtractive Segmentation Approach for the Exhaustive Parallel Quantification of the Extent of Protein Modification at Every Possible Site. Journal of The American Society for Mass Spectrometry, 2016, 27 (8), pp.1328 - 1343. ⟨10.1007/s13361-016-1416-y⟩. ⟨hal-01406961⟩
- Maria joão Marques-Carvalho, Johannes Oppermann, Eva Muñoz, Andreia s. Fernandes, Guillaume Gabant, et al.. Molecular Insights into the Mechanism of Calmodulin Inhibition of the EAG1 Potassium Channel. Structure, 2016, 24 (10), pp.1742 - 1754. ⟨10.1016/j.str.2016.07.020⟩. ⟨hal-01407944⟩
- C. Guarino, M. Legowska, C. Epinette, C. Kellenberger, Sandrine Dallet-Choisy, et al.. New Selective Peptidyl Di(chlorophenyl) Phosphonate Esters for Visualizing and Blocking Neutrophil Proteinase 3 in Human Diseases. Journal of Biological Chemistry, 2014, 289 (46), pp.doi: 10.1074/jbc.M114.591339. ⟨10.1074/jbc.M114.591339⟩. ⟨hal-01179111⟩
- Nicolas Bouchet, Jerome Jaillet, Guillaume Gabant, Benjamin Brillet, Luis Briseño-Roa, et al.. cAMP protein kinase phosphorylates the Mos1 transposase and regulates its activity: evidences from mass spectrometry and biochemical analyses. Nucleic Acids Research, 2014, 42 (2), pp.1117-1128. ⟨10.1093/nar/gkt874⟩. ⟨hal-02132866⟩
- Chrystelle Derache, Christophe Epinette, Alain Roussel, Guillaume Gabant, Martine Cadene, et al.. Crystal structure of greglin, a novel non-classical Kazal inhibitor, in complex with subtilisin.. FEBS Journal, 2012, 279 (24), pp.4466-78. ⟨10.1111/febs.12033⟩. ⟨hal-00817089⟩
- Maria J Marques-Carvalho, Nirakar Sahoo, Frederick W Muskett, Ricardo S Vieira-Pires, Guillaume Gabant, et al.. Structural, Biochemical, and Functional Characterization of the Cyclic Nucleotide Binding Homology Domain from the Mouse EAG1 Potassium Channel.. Journal of Molecular Biology, 2012, 423 (1), pp.34-46. ⟨10.1016/j.jmb.2012.06.025⟩. ⟨hal-00747621⟩
- Philippe Vergne, Marion Maene, Guillaume Gabant, Aurélie Chauvet, Thomas Debener, et al.. Somatic embryogenesis and transformation of the diploid Rosa chinensis cv Old Blush. Plant Cell, Tissue and Organ Culture, 2010, 100 (1), pp.73-78. ⟨10.1007/s11240-009-9621-z⟩. ⟨hal-00734277⟩
- Guillaume Gabant, Alain Lorphelin, Nathalie Nozerand, Charles Marchetti, Laurent Bellanger, et al.. Autophosphorylated Residues Involved in the Regulation of Human Chk2 In Vitro. Journal of Molecular Biology, 2008, 380 (3), pp.489-503. ⟨10.1016/j.jmb.2008.04.053⟩. ⟨hal-02132876⟩
- Guillaume Gabant, Martine Cadène. Mass spectrometry of full-length integral membrane proteins to define functionally relevant structural features. Methods, 2008, 46, pp.54-61. ⟨10.1016/j.ymeth.2008.10.021⟩. ⟨hal-00512469⟩
- Guillaume Gabant, Julie Augier, J. Armengaud. Assessment of solvent residues accessibility using three Sulfo-NHS-biotin reagents in parallel: application to footprint changes of a methyltransferase upon binding its substrate. Journal of Mass Spectrometry, 2008, 43 (3), pp.360-370. ⟨10.1002/jms.1328⟩. ⟨hal-02132921⟩
- Guillaume Gabant, Sylvie Auxilien, Irina Tuszynska, Marie Locard, Michal Gajda, et al.. THUMP from archaeal tRNA:m22G10 methyltransferase, a genuine autonomously folding domain. Nucleic Acids Research, 2006, 34 (9), pp.2483-2494. ⟨10.1093/nar/gkl145⟩. ⟨hal-02132929⟩
Communication dans un congrès1 document
- G. Gabant, A. Boyer, Y. Berteaux, Martine Cadene. SSPaQ: a new method for the quantification of modification at all possible sites of a protein. 33es Journées de la Société Française de Spectrométrie de Masse, Sep 2016, Bordeaux, France. ⟨hal-02902960⟩
Poster9 documents
- Camille Pasquet, Jean-Marc Bonmatin, Cyril Colas, Guillaume Gabant, Gaëtan Glauser, et al.. Exposition humaine aux fongicides SDHIs par les denrées alimentaires. 50e congrès du Groupe Français des Pesticides, May 2022, Namur, Belgique. 2022. ⟨hal-03870671⟩
- David Gosset, Julien Sobilo, Herve Meudal, Frederic Szeremeta, Marylène Bertrand, et al.. Plateforme MO2VING: from MOlecular Organization to in Vivo ImagiNG. 34ème Colloque Biotechnocentre, Oct 2022, Nouan Le Fuzelier, France. ⟨hal-03863246⟩
- G. Gabant, M. Nemcic, J. Pinetre, Martine Cadene. Tuning ETD Top Down MS parameters on a UHR-QTOF instrument to improve protein the fragmentation coverage. SMMAP 2019, Sep 2019, Strasbourg, France. ⟨hal-02902968⟩
- T. Bijot, G. Gabant, Martine Cadene. Development of an original footprinting approach to localize non-covalent ligand binding sites. 30e Colloque Biotechnocentre, Oct 2017, Seillac, France. ⟨hal-02902974⟩
- T. Bijot, G. Gabant, Martine Cadene. Towards a faster localization of noncovalent ligand binding sites using an original footprinting method. 11es Journées du Cancéropôle Grand Ouest, Jun 2017, Vannes, France. ⟨hal-02902989⟩
- T. Bijot, G. Gabant, Martine Cadene. Towards a faster localization of noncovalent ligand binding sites using an original footprinting method. SMMAP 2017, Oct 2017, Marne-la-Vallée, France. ⟨hal-02902978⟩
- G. Gabant, Martine Cadene. Assessing chemical labeling of proteins by mass spectrometry: MALDI−TOF to the rescue of ESI−HRMS. SMMAP 2017, Oct 2017, Marne-la-Vallée, France. ⟨hal-02902984⟩
- G. Gabant, A. Boyer, Martine Cadene. SSPaQ: a subtractive method for the parallel quantification of the degree of modification at every possible site of a protein. 64th ASMS Conference, Jun 2016, San-Antonio, Texas, United States. ⟨hal-02903009⟩
- G. Gabant, Y. Richer, S. Motteau, E. Mebold, Martine Cadene. Towards a prediction of protein reactivity against electrophile ligands: 1. Ranking amino acid side chain nucleophilicities. 64th ASMS Conference, Jun 2016, San Antonio, Texas, United States. ⟨hal-02903017⟩