CBM researchers have developed the first molecular probe compatible with 2 existing imaging techniques: near infrared luminescence (NIR) and photoacoustic signal detection (PA) to improve image contrast.

Researchers in the "Lanthanide Luminescent Compounds, Spectroscopy and Optical Bioimaging" team have designed a molecular probe that can image living organisms using both near-infrared (NIR) luminescence and photoacoustic (PA) signal detection. These two complementary imaging techniques make it possible to monitor biological events precisely, in real time and non-invasively.

A Dual-Mode Near-Infrared Optical and Photoacoustic Imaging Agent Based on a Low Energy Absorbing Ytterbium Complex
Anton Kovalenko, Svetlana V. Eliseeva, Guillaume Collet, Saïda El Abdellaoui, Sharuja Natkunarajah, Stéphanie Lerondel, Laure Guénée, Céline Besnard & Stéphane Petoud
JACS 2024
https://doi.org/10.1021/jacs.4c03406

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