CASTAING Bertrand

email : bertrand.castaing[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.78.43

Research director, Leader of the Team  “Post-translational modifications of proteins and DNA repair: structure, function and dynamic”

 


84 documents

Article dans une revue45 documents

  • Xhaferr Tanushi, Guillaume Pinna, Marie Vandamme, Capucine Siberchicot, Ostiane D’augustin, et al.. OGG1 competitive inhibitors show important off-target effects by directly inhibiting efflux pumps and disturbing mitotic progression. Frontiers in Cell and Developmental Biology, 2023, 11, pp.1124960. ⟨10.3389/fcell.2023.1124960⟩. ⟨hal-04016264⟩
  • Ostiane d'Augustin, Virginie Gaudon, Capucine Siberchicot, Rebecca Smith, Catherine Chapuis, et al.. Identification of key residues of the DNA glycosylase OGG1 controlling efficient DNA sampling and recruitment to oxidized bases in living cells. Nucleic Acids Research, 2023, 51 (10), pp.4942-4958. ⟨10.1093/nar/gkad243⟩. ⟨hal-04088267v2⟩
  • Kiyoto Kamagata, Nanako Iwaki, Saori Kanbayashi, Trishit Banerjee, Rika Chiba, et al.. Structure-dependent recruitment and diffusion of guest proteins in liquid droplets of FUS. Scientific Reports, 2022, 12 (1), pp.7101. ⟨10.1038/s41598-022-11177-w⟩. ⟨hal-03927893⟩
  • Coste Franck, Stéphane Goffinont, Julien Cros, Virginie Gaudon, Guérin Martine, et al.. Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Research, 2022, ⟨10.1093/nar/gkac932⟩. ⟨hal-03841526⟩
  • Kiyoto Kamagata, Nanako Iwaki, Milan Kumar Hazra, Saori Kanbayashi, Trishit Banerjee, et al.. Molecular principles of recruitment and dynamics of guest proteins in liquid droplets. Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-98955-0⟩. ⟨hal-03433608⟩
  • Alan Wacquiez, Franck Coste, Emmanuel Kut, Virginie Gaudon, Sascha Trapp, et al.. Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1. Viruses, 2020, 12 (9), 25 p. ⟨10.3390/v12090947⟩. ⟨hal-03082436⟩
  • Charlotte Rieux, Stéphane Goffinont, Franck Coste, Zahira Tber, Julien Cros, et al.. Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights. International Journal of Molecular Sciences, 2020, 21 (6), pp.2058. ⟨10.3390/ijms21062058⟩. ⟨hal-03082414⟩
  • Karine Loth, Justine Largillière, Franck Coste, Françoise Culard, Céline Landon, et al.. New protein-DNA complexes in archaea: a small monomeric protein induces a sharp V-turn DNA structure. Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-50211-2⟩. ⟨hal-02306224⟩
  • Zahira Tber, Nicolas G. Biteau, Luigi Agrofoglio, Julien Cros, Stéphane Goffinont, et al.. Microwave-assisted Suzuki-Miyaura and Sonogashira coupling of 4-Chloro-2-(trifluoromethyl)pyrido[1,2-e]purine derivatives. European Journal of Organic Chemistry, 2019, 2019, pp.5756-5767. ⟨10.1002/ejoc.201900921⟩. ⟨hal-02347523⟩
  • Martine Beaufour, David Ginguené, Rémy Le Meur, Bertrand Castaing, Martine Cadène. Liquid Native MALDI Mass Spectrometry for the Detection of Protein-Protein Complexes. Journal of The American Society for Mass Spectrometry, 2018, 29 (10), pp.1981-1994. ⟨10.1007/s13361-018-2015-x⟩. ⟨hal-01965971⟩
  • Serge Boiteux, Franck Coste, Bertrand Castaing. Repair of 8-oxo-7,8-dihydroguanine in prokaryotic and eukaryotic cells: Properties and biological roles of the Fpg and OGG1 DNA N -glycosylases. Free Radical Biology and Medicine, 2017, 107, pp.179 - 201. ⟨10.1016/j.freeradbiomed.2016.11.042⟩. ⟨hal-01618166⟩
  • R. Le Meur, Françoise Culard, V. Nadan, S. Goffinont, F. Coste, et al.. The nucleoid-associated protein HU enhances 8-oxoguanine base excision by the formamidopyrimidine-DNA glycosylase. Biochemical Journal, 2015, 471 (1), pp.13-23. ⟨10.1042/BJ20150387⟩. ⟨hal-01216639⟩
  • Rémy Le Meur, Karine Loth, Françoise Culard, Bertrand Castaing, Céline Landon. Backbone assignment of the three dimers of HU from Escherichia coli at 293 K: EcHUα2, EcHUβ2 and EcHUαβ. Biomolecular NMR Assignments, 2015, 9 (2), pp.359-363. ⟨10.1007/s12104-015-9610-6⟩. ⟨hal-01171467⟩
  • F. d'Heygere, A. Schwartz, F. Coste, B. Castaing, M. Boudvillain. ATP-dependent motor activity of the transcription termination factor Rho from Mycobacterium tuberculosis. Nucleic Acids Research, 2015, 43 (12), pp.6099-60111. ⟨10.1093/nar/gkv505⟩. ⟨hal-01171219⟩
  • A. Biela, F. Coste, F. Culard, M. Guerin, S. Goffinont, et al.. Zinc finger oxidation of Fpg/Nei DNA glycosylases by 2-thioxanthine: biochemical and X-ray structural characterization. Nucleic Acids Research, 2014, 42 (16), pp.doi: 10.1093/nar/gku613. ⟨10.1093/nar/gku613⟩. ⟨hal-01175522⟩
  • Françoise Paquet, Olivier Delalande, Stephane Goffinont, Françoise Culard, Karine Loth, et al.. Model of a DNA-protein complex of the architectural monomeric protein MC1 from Euryarchaea. PLoS ONE, 2014, 9 (2), pp.e88809. ⟨10.1371/journal.pone.0088809⟩. ⟨hal-01063974⟩
  • Sylvie Baucheron, Franck Coste, Sylvie Canepa, Marie-Christine Maurel, Etienne Giraud, et al.. Binding of the RamR repressor to wild-type and mutated promoters of the RamA gene involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium.. Antimicrobial Agents and Chemotherapy, 2012, 56 (2), pp.942-8. ⟨10.1128/AAC.05444-11⟩. ⟨hal-00721770⟩
  • Béatrice Matot, Yann-Vaï Le Bihan, Rachel Lescasse, Javier Pérez, Simona Miron, et al.. The orientation of the C-terminal domain of the Saccharomyces cerevisiae Rap1 protein is determined by its binding to DNA. Nucleic Acids Research, 2012, 40 (7), pp.3197-207. ⟨10.1093/nar/gkr1166⟩. ⟨hal-00720647⟩
  • Norbert Garnier, Karine Loth, Franck Coste, Rafal Augustyniak, Virginie Nadan, et al.. An alternative flexible conformation of the E. coli HU beta(2) protein: structural, dynamics, and functional aspects. European Biophysics Journal, 2011, 40 (2), pp.117-129. ⟨10.1007/s00249-010-0630-y⟩. ⟨hal-00602370⟩
  • Yann Vei Le Bihan, Angeles M. Izquierdo, Franck Coste, Pierre Aller, Françoise Culard, et al.. 5-Hydroxy-5-methylhydantoin DNA lesion, a molecular trap for DNA glycosylases. Nucleic Acids Research, 2011, 39 (14), pp.6277-6290. ⟨10.1093/nar/gkr215⟩. ⟨hal-00614943⟩
  • Franck Coste, Matthias Ober, Yann-Vaï Le Bihan, Maria Angeles Izquierdo, Nadège Hervouet, et al.. Bacterial base excision repair enzyme Fpg recognizes bulky N7-substituted-FapydG lesion via unproductive binding mode.. Chemistry & Biology / Chemistry and Biology; CHEMISTRY & BIOLOGY, 2008, 15 (7), pp.706-17. ⟨10.1016/j.chembiol.2008.05.014⟩. ⟨hal-00408047⟩
  • Irina Gutsche, Andreja Vujicić-Zagar, Xavier Siebert, Pascale Servant, Françoise Vannier, et al.. Complex oligomeric structure of a truncated form of DdrA: A protein required for the extreme radiotolerance of Deinococcus.. Biochimica et Biophysica Acta - Molecular Cell Research, 2008, 1784 (7-8), pp.1050-8. ⟨10.1016/j.bbapap.2008.03.009⟩. ⟨hal-00297143⟩
  • Mathieu Creyssels, Éric Falcon, Bertrand Castaing. Scaling of ac electrical conductivity of powders under compression. Physical Review B: Condensed Matter and Materials Physics (1998-2015), 2008, 77 (7), pp.075135. ⟨10.1103/PhysRevB.77.075135⟩. ⟨hal-00264434⟩
  • Mathieu Creyssels, Stéphane Dorbolo, Alexandre Merlen, Claude Laroche, Bertrand Castaing, et al.. Some aspects of electrical conduction in granular systems of various dimensions. European Physical Journal E: Soft matter and biological physics, 2007, 23, pp.255. ⟨10.1140/epje/i2006-10186-9⟩. ⟨hal-00170319v3⟩
  • Marie Davídková, Viktorie Stísová, Stéphane Goffinont, Nathalie Gillard, Bertrand Castaing, et al.. Modification of DNA radiolysis by DNA-binding proteins: structural aspects. Radiation Protection Dosimetry, 2006, 122 (1-4), pp.100-105. ⟨10.1093/rpd/ncl442⟩. ⟨hal-00168743⟩
  • C. Buré, B. Castaing, C. Lange, A.F. Delmas. Location and base selectivity on fragmentation of brominated oligodeoxynucleotides. Journal of Mass Spectrometry, 2006, 41 (1), pp.84-90. ⟨10.1002/jms.967⟩. ⟨hal-00088837⟩
  • F. Coste, M. Ober, T. Carrell, S. Boiteux, C. Zelwer, et al.. Structural basis for the recognition of the FapydG lesion (2,6-diamino-4-hydroxy-5-formamidopyrimidine) by Formamidopyrimidine-DNA glycosylase. Journal of Biological Chemistry, 2006, 279 (42), pp.44074-44083. ⟨10.1074/jbc.M405928200⟩. ⟨hal-00114389⟩
  • Stéphane Boiteux, Bertrand Castaing, J.P. Radicella. BER: (Base excision repair): molecular mechanisms and biological roles. Biofutur, 2006, 25 (271), pp.35-39. ⟨hal-00387927⟩
  • M. Bégusovà, N. Gillard, D. Sy, B. Castaing, M. Charlier, et al.. Radiolysis of DNA-protein complexes. Radiation Physics and Chemistry, 2005, 72, pp.265-270. ⟨hal-00088505⟩
  • K. Pereira de Jesus, L. Serre, C. Zelwer, B. Castaing. Structural insights into abasic site for Fpg specific binding and catalysis: comparative high-resolution crystallographic studies of Fpg bound to various models of abasic site analogues containing DNA. Nucleic Acids Research, 2005, 33, pp.5936-5944. ⟨hal-00088666⟩
  • N. Gillard, M. Bégusovà, B. Castaing, M. Spotheim-Maurizot. Radiation affects binding of Fpg repair protein to an abasic site containing DNA. Radiation Research, 2004, 162, pp.566-571. ⟨10.1667/RR3247⟩. ⟨hal-00113044⟩
  • Patricia Amara, Laurence Serre, B. Castaing, A. Thomas. Insights into the DNA repair process by the formamidopyrimidine-DNA glycosylase investigated by molecular dynamics. Journal of Biological Chemistry, 2004, 13 (8), pp.2009-2021. ⟨10.1110/ps.04772404⟩. ⟨hal-00088335⟩
  • E. Muller, D. Gasparutto, B. Castaing, A. Favier, J. Cadet. Recognition of cyclonucleoside lesions by the Lactococcus lactis FPG protein. Nucleosides, Nucleotides and Nucleic Acids, 2003, 22, pp.1563-1565. ⟨hal-00088198⟩
  • Charles Ramstein, Nadège Hervouet, Franck Coste, Charles Zelwer, Jacques Oberto, et al.. Evidence of a thermal unfolding dimeric intermediate for the Escherichia coli histone-like HU proteins: thermodynamics and structure.. Journal of Molecular Biology, 2003, 331 (1), pp.101-21. ⟨hal-02127656⟩
  • Laurence Serre, Karine Pereira de Jésus, Serge Boiteux, Charles Zelwer, Bertrand Castaing. Crystal structure of the Lactococcus lactis formamidopyrimidine-DNA glycosylase bound to an abasic site analogue-containing DNA. EMBO Journal, 2002, 21 (12), pp.2854-2865. ⟨10.1093/emboj/cdf304⟩. ⟨hal-02141118⟩
  • Karine Pereira de Jésus, Laurence Serre, Nadège Hervouet, Véronique Bouckson-Castaing, Charles Zelwer, et al.. Crystallization and preliminary X-ray crystallographic studies of a complex between the Lactococcus lactis Fpg DNA-repair enzyme and an abasic site containing DNA. Acta crystallographica Section D : Structural biology [1993-..], 2002, 58 (4), pp.679-682. ⟨10.1107/S0907444902001397⟩. ⟨hal-02141124⟩
  • N Guibourt, Bertrand Castaing, P van Der Kemp, S. Boiteux. Catalytic and DNA binding properties of the ogg1 protein of Saccharomyces cerevisiae: comparison between the wild type and the K241R and K241Q active-site mutant proteins.. Biochemistry, 2000, 39 (7), pp.1716-24. ⟨hal-02141126⟩
  • Martial Thomas, Bertrand Castaing, Jean-Louis Fourrey, Charles Zelwer. Synthesis of an Enantiomerically Pure Carbocyclic DNA Abasic Site Analogue. Nucleosides and Nucleotides, 1999, 18 (2), pp.239-243. ⟨10.1080/15257779908043071⟩. ⟨hal-02141150⟩
  • Bertrand Castaing, Jean-Louis Fourrey, Nadege Hervouet-Coste, Martial Thomas, Serge Boiteux, et al.. AP site structural determinants for Fpg specific recognition. Nucleic Acids Research, 1999, 27 (2), pp.608-615. ⟨10.1093/nar/27.2.608⟩. ⟨hal-02141144⟩
  • Franck Coste, N. Hervouet, J. Oberto, C. Zelwer, Bertrand Castaing. Crystallization and preliminary X-ray diffraction analysis of the homodimeric form alpha2 of the HU protein from Escherichia coli.. Acta crystallographica Section D : Structural biology [1993-..], 1999, 55 (Pt 11), pp.1952-4. ⟨hal-02127644⟩
  • Bertrand Castaing, Charles Zelwer, Jacques Laval, Serge Boiteux. HU Protein of Escherichia coli Binds Specifically to DNA That Contains Single-strand Breaks or Gaps. Journal of Biological Chemistry, 1995, 270 (17), pp.10291-10296. ⟨10.1074/jbc.270.17.10291⟩. ⟨hal-02141159⟩
  • Bertrand Castaing, Albert Geiger, Hartmut Seliger, Peter Nehls, Jacques Laval, et al.. Cleavage and binding of a DNA fragment containing a single 8-oxoguanine by wild type and mutant FPG proteins. Nucleic Acids Research, 1993, 21 (12), pp.2899-2905. ⟨10.1093/nar/21.12.2899⟩. ⟨hal-02141167⟩
  • T.R O'Connor, R.J Graves, G. de Murcia, Bertrand Castaing, J Laval. Fpg protein of Escherichia coli is a zinc finger protein whose cysteine residues have a structural and/or functional role.. Journal of Biological Chemistry, 1993, 268 (12), pp.9063-70. ⟨hal-02141187⟩
  • Bertrand Castaing, Serge Boiteux, Charles Zelwer. DNA containing a chemically reduced apurinic site is a high affinity ligand for the E.coli formamidopyrimidine-DNA glycosyiase. Nucleic Acids Research, 1992, 20 (3), pp.389-394. ⟨10.1093/nar/20.3.389⟩. ⟨hal-02141191⟩
  • W Zagorski, Bertrand Castaing, C.J Herbert, M Labouesse, R Martin, et al.. Purification and characterization of the Saccharomyces cerevisiae mitochondrial leucyl-tRNA synthetase.. Journal of Biological Chemistry, 1991, 266 (4), pp.2537-41. ⟨hal-02141199⟩

Communication dans un congrès7 documents

  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. Architecture et dynamique de protéines histone-like de bactérie et d’archées. Journée BioRMN IdF, Sep 2020, Gif-sur-Yvette, France. ⟨hal-03053296⟩
  • Bertrand Castaing. Inhibition des ADN glycosylases de la super famille structurale Fpg/Nei par des thiopurines: relations structure-activité. Journée scientifique de la Fédération de Recherche 2708, Apr 2019, Orléans, France. ⟨hal-02903112⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. Vers une description cinétique et structurale complète du mécanisme d'échange de chaînes de la protéine HU d'Escherichia coli.. XXXIe congrès du GERM (Groupement d'Etudes de Résonance Magnétique), May 2019, Oléron, France. ⟨hal-02361645⟩
  • Bertrand Castaing. Les ADN glycosylases qui initient le système de réparation de l'ADN par excision de base, de nouvelles cibles potentielles pour lutter contre le cancer. Colloque du Réseau « Molécules marines, métabolisme et cancer » du Canréropôle Grand Ouest, May 2019, Mansigné, France. ⟨hal-02903074⟩
  • J. Cros, F. Coste, S. Goffinont, Virginie Nadan, V. Roy, et al.. Discovery and characterization of inhibitors of the DNA repair enzymes hNEIL1 and hOGG1, pertinent therapeutic targets for cancer therapy. Laboratoire International Associé, Jun 2019, Varsovie, Poland. ⟨hal-02903108⟩
  • J. Cros, F. Coste, Z. Tber, S. Goffinont, Virginie Nadan, et al.. Small molecule inhibitors of the human DNA glycosylases hOGG1 and NEIL1, pertinent therapeutic targets in cancer and neurodegenerative disease therapies. 25th Young Research Fellows Meeting, Mar 2018, Orléans, France. ⟨hal-02903084⟩
  • Daniel Marc, Franck Coste, Bertrand Castaing. Des cristaux pour la recherche de nouveaux antiviraux. Journées d'Animation Scientifique de la Fédération de Recherche d'Infectiologie (FéRI), Oct 2015, Orléans, France. 17 diapositives. ⟨hal-02792217⟩

Poster29 documents

  • Lucija Mance, Nicolas Bigot, Edison Zhamungui Sánchez, Franck Coste, Natalia Martín-González, et al.. Studies of BTB domain polymerisation through integrative structural biology. FRISBI User Meeting 2024, CNRS campus Gif-sur-Yvette, Jan 2024, Gif sur Yvette, France. ⟨hal-04778726⟩
  • Daniel Marc, Alan Wacquiez, Stéphane Goffinont, Virginie Nadan, Franck Coste, et al.. Interaction de la protéine NS1 des virus influenza A avec l’ARN : mécanismes impliqués dans la reconnaissance spécifique. XIIes Journées Francophones de Virologie, Mar 2019, Lyon, France. Virologie, 23, 2019. ⟨hal-02737761⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system.. Journée Fédération de recherche “Physique et Chimie du Vivant”, Apr 2019, Orléans, France. ⟨hal-02362578⟩
  • J. Cros, F. Coste, S. Goffinont, V. Gaudon, V. Roy, et al.. Search for small molecule inhibitors of the DNA repair enzymes hNEIL1 and hOGG1, potential therapeutic targets in cancer. 13th French 3R meeting, May 2019, Presqu’île de Giens, France. ⟨hal-02903219⟩
  • J. Cros, F. Coste, S. Goffinont, V. Gaudon, V. Roy, et al.. Search for small molecule inhibitors of the DNA repair enzymes hNEIL1 and hOGG1, potential therapeutic targets in cancer. Journée Fédération de recherche “Physique et Chimie du Vivant” FR2708 (CBM/ICOA), Apr 2019, Orléans, France. ⟨hal-02903223⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system. NMR : a tool for biology XITh, Jan 2019, Paris, France. ⟨hal-02362588⟩
  • Julien Cros, Franck Coste, Stéphane Goffinont, Virginie Nadan, Norbert Garnier, et al.. Screening, characterization and structural studies of small molecules inhibitors of the DNA glycosylase hNEIL1 and hOGG1, potential therapeutic targets in cancer and neurodegenerative disease. 1st French congress on Integrative Structural Biology (BSI-2019), Oct 2019, Toulouse, France. ⟨hal-03385201⟩
  • F. Coste, G. Chaume, J.-B. Madinier, I. Rahioui, B. Castaing, et al.. Incorporation of trifluoromethylated pseudoproline in an entomotoxic knottin: effects on oxidative folding, 3D structure and biological activity. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02893471⟩
  • Alan Wacquiez, Franck Coste, Caroline Blondeau, Emmanuel Kut, Virginie Nadan, et al.. NS1 des virus Influenza A : approches structurales et fonctionnelles pour de nouvelles stratégies anti-virales. 20. Journées Francophones de Virologie 2018, Mar 2018, Paris, France. John Libbey Eurotext, Virologie, 22, 148 p., 2018. ⟨hal-02736544⟩
  • Justine Largillière, Rémy Le Meur, Norbert Garnier, Celine Landon, A.F. Delmas, et al.. Native and Intermediate conformations of the three HU dimers of E.coli.. 28th ICMRBS - International Council on Magnetic Resonance in Biological Systems, Aug 2018, Dublin, Ireland. ⟨hal-02362585⟩
  • J. Cros, F. Coste, S. Goffinont, V. Gaudon, V. Roy, et al.. Recherche d’inhibiteurs des enzymes de réparation de l’ADN hNeil1 et hOGG1, de nouvelles cibles pertinentes pour le développement de thérapies anticancéreuses. 31e colloque Biotechnocentre, Oct 2018, Seillac, France. ⟨hal-02904682⟩
  • Karine Loth, Françoise Culard, Justine Largillière, Celine Landon, Bertrand Castaing, et al.. New protein-DNA complexes in archaea: a monomeric protein induces a U-turn structure.. 5e séminaire scientifique du LIA MiR-TANGo, May 2018, Orléans, France. ⟨hal-02362804⟩
  • Justine Largillière, Rémy Le Meur, Martine Cadene, Bertrand Castaing, Karine Loth, et al.. Premières études cinétiques du mécanisme d’échange de chaînes de la protéine HU d’Escherischia coli.. Journée Fédération de recherche “Physique et Chimie du Vivant”, Jan 2018, Orléans, France. ⟨hal-02362577⟩
  • F. Coste, G. Chaume, J.-B. Madinier, I. Rahioui, B. Castaing, et al.. Incorporation of trifluoromethylated pseudoproline in an entomotoxic knottin: effects on oxidative folding, 3D structure and biological activity. 35th European Peptide Symposium (EPS35), Aug 2018, Dublin, Ireland. ⟨hal-02894161⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Celine Landon, A.F. Delmas, et al.. First kinetics description of the EcHU chain exchange system.. 28th ICMRBS - International Council on Magnetic Resonance in Biological Systems, Aug 2018, Dublin, Ireland. ⟨hal-02362586⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system.. 31e colloque Biotechnocentre, Oct 2018, Seillac, France. ⟨hal-02362818⟩
  • Karine Loth, Justine Largillière, Franck Coste, Françoise Culard, Celine Landon, et al.. New protein-DNA complexes in archaea: a small monomeric protein induces a sharp V-turn DNA structure.. EuroMar 2018, Jul 2018, Nantes, France. ⟨hal-02362581⟩
  • Alan Wacquiez, Stéphane Goffinont, Virginie Nadan, Franck Coste, Emmanuel Kut, et al.. Structures et fonctions de la protéine NS1 des virus influenza pour la recherche de nouvelles cibles thérapeutiques. 31e Colloque Biotechnocentre, Oct 2018, Seillac, France. , 2018. ⟨hal-02736195⟩
  • Karine Loth, Justine Largillière, Franck Coste, Françoise Culard, Bertrand Castaing, et al.. New protein-DNA complexes in archaea: a small monomeric protein induces a V-turn structure.. 28th ICMRBS - International Council on Magnetic Resonance in Biological Systems, Aug 2018, Dublin, Ireland. ⟨hal-02362584⟩
  • Justine Largillière, Rémy Le Meur, Martine Cadene, Bertrand Castaing, Karine Loth, et al.. Premières études cinétiques du mécanisme d’échange de chaînes de la protéine HU d’Escherischia coli.. 16e colloque scientifique de l’ADOC : Converger pour Renforcer, Apr 2018, Orléans, France. ⟨hal-02362579⟩
  • J. Cros, F. Coste, Z. Tber, S. Goffinont, V. Nadan, et al.. Search for small molecule inhibitors of DNA glycosylases, pertinent therapeutic targets in cancer and neurodegenerative disease therapies. 5e Colloque annuel du Laboratoire International Associé (LIA) MiR-TANGo, May 2018, Orléans, France. ⟨hal-02904701⟩
  • Karine Loth, Françoise Culard, Justine Largillière, Celine Landon, Bertrand Castaing, et al.. The MC1-DNA complex solution structure reveals that a monomeric protein can induce a U-turn in archaea.. NMR: a tool for biology XTh, Jan 2017, Paris, France. ⟨hal-02361613⟩
  • Justine Largillière, Rémy Le Meur, Martine Cadene, Bertrand Castaing, Karine Loth, et al.. Première description cinétique du mécanisme d’échange de chaînes de la protéine HU d'Escherichia coli.. 30e colloque Biotechnocentre, Oct 2017, Seillac, France. ⟨hal-02361632⟩
  • A. Wacquiez, F. Coste, V. Nadan, E. Kut, S. Goffinont, et al.. NS1 of Influenza viruses: structural and functional approaches towards the discovery of novel anti-influenza drugs. Le Studium Conférence “Structural Biology and biophysics of RNA-protein complexes”, Nov 2017, Orléans, France. ⟨hal-02904778⟩
  • Karine Loth, Justine Largillière, Franck Coste, A.F. Delmas, Bertrand Castaing, et al.. New protein-DNA complexes in archaea: a monomeric protein induces a U-turn structure.. Le Studium Confenrence: Structural biology and biophysics of RNA-protein complexes, Nov 2017, Orléans, France. ⟨hal-02362576⟩
  • A. Wacquiez, F. Coste, C. Blondeau, E. Kut, V. Nadan, et al.. NS1 des virus Influenza A : approches structurales et fonctionnelles pour de nouvelles stratégies anti-virales. Le Studium Conférence « Messenger RNA therapeutics : advances and perspectives », Mar 2017, Orléans, France. ⟨hal-02904828⟩
  • A. Wacquiez, S. Goffinont, V. Nadan, F. Coste, E. Kut, et al.. NS1 des virus influenza : relations structure-fonction pour la recherche de nouveaux anti-viraux. 30e colloque Biotechnocentre, Oct 2017, Seillac, France. ⟨hal-02904785⟩
  • C. Rieux, F. Coste, F. Culard, S. Goffinont, S. Bourg, et al.. Small-molecule inhibitors of Fpg/Nei DNA glycosylases, enzymes initiating the base excision repair pathway, new targets for cancer therapy. XXII International Roundtable on Nucleosides, Nucleotides and Nucleic Acids, Jul 2016, Paris, France. ⟨hal-02919151⟩
  • Mathieu Galibert, Chrystelle Derache, Franck Coste, Hervé Meudal, Anne-Christine Lalmanach, et al.. Improvement of the chemical production of β-defensins including straightforward attribution of disulfide bridges. 18. Réunion du GFPP, May 2013, Sète, France. 1 p., 2013. ⟨hal-02805308⟩

Ouvrage (y compris édition critique et traduction)1 document

  • Kadija Essalhi, L. Gellon, Julie Berthault, Françoise Culard, Martine Guerin, et al.. Ogg1, a Saccharomyces cerevisiae bifunctional DNA glycosylase involved in base excision repair of oxidative DNA damage, interacts with the replicative DNA polymerase, Pol epsilon. pp.409, 2011. ⟨hal-00614891⟩

Chapitre d'ouvrage2 documents

  • F. d'Heygère, A. Schwartz, F. Coste, B. Castaing, M. Boudvillain. Monitoring RNA Unwinding by the Transcription Termination Factor Rho from Mycobacterium tuberculosis. Methods in Mecular Biology, 1259, Springer, pp.293-311, 2015, RNA remodelling proteins (Boudvillain, ed), 978-1-4939-2213-0. ⟨10.1007/978-1-4939-2214-7_18⟩. ⟨hal-01174055⟩
  • Evelyne Sage, Bertrand Castaing. Radiation damage to biomolecules, radioprotection and radiotherapy. Genome maintenance mechanisms in response to radiation-induced DNA damage. Mélanie Spotheim-Maurizot. Radiation chemistry from basics to applications in material and life sciences, EDP Sciences, pp.219-232, 2008. ⟨hal-00284342⟩

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