The "Metal Complexes and MRI" team, in collaboration with a Hungarian team, has developed a contrast agent based on an iron compound associated with a fluorinated ligand. This makes it possible to map oxidative stress in living tissue, a marker of numerous pathologies. This molecular detector, still at the pre-clinical stage, could considerably enrich tomorrow's medical imaging toolkit.

This major advance has been published in the journal JACS.
Relaxation-Based In Vivo Discrimination of Oxidized and Reduced States of a Redox-Switchable 19F MRI Probe
Garda Z., Szeremeta F., Tóth C.S., Bunda S., Pifferi C., Clémençon R., Même S., Tircso G., Tóth É.
J. Am. Chem. Soc. 2025, 147, 21, 18017-18024

Find out more on the CNRS Chimie website.