Researchers from the group "Luminescent lanthanide compounds, spectroscopy and optical bioimaging" and the University of Pittsburgh (USA) have designed a rigid three-dimensional chemical system of organometallic network type composed of lanthanides and organic molecules. A major originality of this work is based on the use of the cavity of this network to generate in situ the molecular system sensitizing the lanthanide cations. This new approach has the advantage, among other things, of allowing the excitation length to be controlled. This network is well suited to the real conditions of optical biomedical imaging on living cells.
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These researches have been published on Journal of American Chemical Society
Patrick F. Muldoon, Guillaume Collet, Svetlana V Eliseeva, Tian-Yi Luo, Stephane Petoud, and Nathaniel L Rosi. Ship-in-a-bottle preparation of long wavelength molecular antennae in lanthanide metal-organic frameworks for biological imaging. J. Am. Chem. Soc. (2020) 142, 8776-8781 - doi : 10.1021/jacs.0c01426