GABANT Guillaume

email : guillaume.gabant[remplacer_par_at]cnrs-orleans.fr

Phone : 02.38.25.54.57

Engineer in chemical analysis within the thematic group Functional Mass Spectrometry in Metastasis and technical responsible of the facility for mass spectrometry and proteomics

 



23 documents

Article dans une revue

  • Koffi N’guessan, Renata Grzywa, Seda Seren, Guillaume Gabant, Maria Juliano, et al.. Human proteinase 3 resistance to inhibition extends to alpha‐2 macroglobulin. FEBS Journal, Wiley, 2020, ⟨10.1111/febs.15229⟩. ⟨hal-02901768⟩
  • Francisco Rodrigues, Thomas Georgelin, Guillaume Gabant, Baptiste Rigaud, Fabrice Gaslain, et al.. Confinement and Time Immemorial: Prebiotic Synthesis of Nucleotides on a Porous Mineral Nanoreactor. Journal of Physical Chemistry Letters, American Chemical Society, 2019, 10 (15), pp.4192-4196. ⟨10.1021/acs.jpclett.9b01448⟩. ⟨hal-02308428⟩
  • Artur Castro-Rodrigues, Yaxian Zhao, Fátima Fonseca, Guillaume Gabant, Martine Cadène, et al.. The Interaction between the Drosophila EAG Potassium Channel and the Protein Kinase CaMKII Involves an Extensive Interface at the Active Site of the Kinase. Journal of Molecular Biology, Elsevier, 2018, 430 (24), pp.5029-5049. ⟨hal-01966024⟩
  • Guillaume Gabant, Alain Boyer, Martine Cadene. SSPaQ: A Subtractive Segmentation Approach for the Exhaustive Parallel Quantification of the Extent of Protein Modification at Every Possible Site. Journal of The American Society for Mass Spectrometry, Springer Verlag (Germany), 2016, 27 (8), pp.1328 - 1343. ⟨10.1007/s13361-016-1416-y⟩. ⟨hal-01406961⟩
  • Maria joão Marques-Carvalho, Johannes Oppermann, Eva Muñoz, Andreia s. Fernandes, Guillaume Gabant, et al.. Molecular Insights into the Mechanism of Calmodulin Inhibition of the EAG1 Potassium Channel. Structure, Elsevier (Cell Press), 2016, 24 (10), pp.1742 - 1754. ⟨10.1016/j.str.2016.07.020⟩. ⟨hal-01407944⟩
  • Nicolas Bouchet, Jerome Jaillet, Guillaume Gabant, Benjamin Brillet, Luis Briseño-Roa, et al.. cAMP protein kinase phosphorylates the Mos1 transposase and regulates its activity: evidences from mass spectrometry and biochemical analyses. Nucleic Acids Research, Oxford University Press, 2014, 42 (2), pp.1117-1128. ⟨10.1093/nar/gkt874⟩. ⟨hal-02132866⟩
  • C. Guarino, M. Legowska, C. Epinette, C. Kellenberger, S. Dallet-Choisy, et al.. New Selective Peptidyl Di(chlorophenyl) Phosphonate Esters for Visualizing and Blocking Neutrophil Proteinase 3 in Human Diseases. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2014, 289 (46), pp.doi: 10.1074/jbc.M114.591339. ⟨10.1074/jbc.M114.591339⟩. ⟨hal-01179111⟩
  • Chrystelle Derache, Christophe Epinette, Alain Roussel, Guillaume Gabant, Martine Cadene, et al.. Crystal structure of greglin, a novel non-classical Kazal inhibitor, in complex with subtilisin.. FEBS Journal, Wiley, 2012, 279 (24), pp.4466-78. ⟨10.1111/febs.12033⟩. ⟨hal-00817089⟩
  • Maria J Marques-Carvalho, Nirakar Sahoo, Frederick W Muskett, Ricardo S Vieira-Pires, Guillaume Gabant, et al.. Structural, Biochemical, and Functional Characterization of the Cyclic Nucleotide Binding Homology Domain from the Mouse EAG1 Potassium Channel.. Journal of Molecular Biology, Elsevier, 2012, 423 (1), pp.34-46. ⟨10.1016/j.jmb.2012.06.025⟩. ⟨hal-00747621⟩
  • Philippe Vergne, Marion Maene, Guillaume Gabant, Aurélie Chauvet, Thomas Debener, et al.. Somatic embryogenesis and transformation of the diploid Rosa chinensis cv Old Blush. Plant Cell, Tissue and Organ Culture, Springer Verlag, 2010, 100 (1), pp.73-78. ⟨10.1007/s11240-009-9621-z⟩. ⟨hal-00734277⟩
  • Guillaume Gabant, Martine Cadène. Mass spectrometry of full-length integral membrane proteins to define functionally relevant structural features. Methods, Elsevier, 2008, 46, pp.54-61. ⟨10.1016/j.ymeth.2008.10.021⟩. ⟨hal-00512469⟩
  • Guillaume Gabant, Julie Augier, Jean Armengaud. Assessment of solvent residues accessibility using three Sulfo-NHS-biotin reagents in parallel: application to footprint changes of a methyltransferase upon binding its substrate. Journal of Mass Spectrometry, Wiley-Blackwell, 2008, 43 (3), pp.360-370. ⟨10.1002/jms.1328⟩. ⟨hal-02132921⟩
  • Guillaume Gabant, Alain Lorphelin, Nathalie Nozerand, Charles Marchetti, Laurent Bellanger, et al.. Autophosphorylated Residues Involved in the Regulation of Human Chk2 In Vitro. Journal of Molecular Biology, Elsevier, 2008, 380 (3), pp.489-503. ⟨10.1016/j.jmb.2008.04.053⟩. ⟨hal-02132876⟩
  • Guillaume Gabant, Sylvie Auxilien, Irina Tuszynska, Marie Locard, Michal Gajda, et al.. THUMP from archaeal tRNA:m22G10 methyltransferase, a genuine autonomously folding domain. Nucleic Acids Research, Oxford University Press, 2006, 34 (9), pp.2483-2494. ⟨10.1093/nar/gkl145⟩. ⟨hal-02132929⟩

Communication dans un congrès

  • G. Gabant, A. Boyer, Y. Berteaux, Martine Cadene. SSPaQ: a new method for the quantification of modification at all possible sites of a protein. 33es Journées de la Société Française de Spectrométrie de Masse, Sep 2016, Bordeaux, France. ⟨hal-02902960⟩

Poster

  • G. Gabant, M. Nemcic, J. Pinetre, Martine Cadene. Tuning ETD Top Down MS parameters on a UHR-QTOF instrument to improve protein the fragmentation coverage. SMMAP 2019, Sep 2019, Strasbourg, France. ⟨hal-02902968⟩
  • T. Bijot, G. Gabant, Martine Cadene. Development of an original footprinting approach to localize non-covalent ligand binding sites. 30e Colloque Biotechnocentre, Oct 2017, Seillac, France. ⟨hal-02902974⟩
  • T. Bijot, G. Gabant, Martine Cadene. Towards a faster localization of noncovalent ligand binding sites using an original footprinting method. 11es Journées du Cancéropôle Grand Ouest, Jun 2017, Vannes, France. ⟨hal-02902989⟩
  • T. Bijot, G. Gabant, Martine Cadene. Towards a faster localization of noncovalent ligand binding sites using an original footprinting method. SMMAP 2017, Oct 2017, Marne-la-Vallée, France. ⟨hal-02902978⟩
  • G. Gabant, Martine Cadene. Assessing chemical labeling of proteins by mass spectrometry: MALDI−TOF to the rescue of ESI−HRMS. SMMAP 2017, Oct 2017, Marne-la-Vallée, France. ⟨hal-02902984⟩
  • G. Gabant, A. Boyer, Martine Cadene. SSPaQ: a subtractive method for the parallel quantification of the degree of modification at every possible site of a protein. 64th ASMS Conference, Jun 2016, San-Antonio, Texas, United States. ⟨hal-02903009⟩
  • G. Gabant, Y. Richer, S. Motteau, E. Mebold, Martine Cadene. Towards a prediction of protein reactivity against electrophile ligands: 1. Ranking amino acid side chain nucleophilicities. 64th ASMS Conference, Jun 2016, San Antonio, Texas, United States. ⟨hal-02903017⟩

Thèse

  • Guillaume Gabant. Spectrométrie de masse des modifications induites ou post-traductionnelles de protéines : méthodologie et application à des protéines d’intérêt thérapeutique. Biochimie, Biologie Moléculaire. Université d'Orléans, 2014. Français. ⟨NNT : 2014ORLE2061⟩. ⟨tel-01246054⟩