MEUDAL Hervé

email : herve.meudal@cnrs-orleans.fr

Phone : +33 2.38.25.55.46 ou 55.63

Engineer in chemical analysise within the thematic group NMR of biomolecules”

 



56 documents

Article dans une revue

  • Nicolas Guyot, Hervé Meudal, Sascha Trapp, Sophie Iochmann, Anne Silvestre, et al.. Structure, function, and evolution of Gga -AvBD11, the archetype of the structural avian-double-β-defensin family. Proceedings of the National Academy of Sciences of the United States of America , National Academy of Sciences, 2020, 117 (1), pp.337-345. ⟨10.1073/pnas.1912941117⟩. ⟨hal-02522250⟩
  • Claude Zoukimian, Hervé Meudal, Stephan de Waard, Karima Ait Ouares, Sébastien Nicolas, et al.. Synthesis by native chemical ligation and characterization of the scorpion toxin AmmTx3. Bioorganic & Medicinal Chemistry, 2019, 27 (1), pp.247-253. ⟨10.1016/j.bmc.2018.12.009⟩. ⟨hal-02522016⟩
  • Karine Loth, Agnès Vergnes, Cairé Barreto, Sébastien Voisin, Hervé Meudal, et al.. The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets. mBio, American Society for Microbiology, 2019, 10 (5), pii: e01821-19. ⟨10.1128/mBio.01821-19⟩. ⟨hal-02328576⟩
  • Geoffrey Bailleul, Amanda Kravtzoff, Alix Joulin-Giet, Fabien Lecaille, Valérie Labas, et al.. The unusual resistance of avian defensin AvBD7 to proteolytic enzymes preserves its antibacterial activity. PLoS ONE, Public Library of Science, 2016, 11 (8), pp.1-20. ⟨10.1371/journal.pone.0161573⟩. ⟨hal-01594888⟩
  • Fatima Oukhatar, Hervé Meudal, Céline Landon, Nikos K Logothetis, Carlos Platas-Iglesias, et al.. Macrocyclic Gd(3+) Complexes with Pendant Crown Ethers Designed for Binding Zwitterionic Neurotransmitters.. Chemistry - A European Journal, Wiley-VCH Verlag, 2015, 21 (31), pp.11226-11237. ⟨hal-01196981⟩
  • Virginie Hervé, Hervé Meudal, Valérie Labas, Sophie Réhault-Godbert, Joël Gautron, et al.. Three-dimensional NMR Structure of Hen Egg Gallin (Chicken Ovodefensin) Reveals a New Variation of the β-Defensin Fold. Journal of Biological Physics and Chemistry, Basel, Switzerland : Collegium Basilea (Institute of Advanced Study) ; Tbilisi : Association of Modern Scientific Investigation (AMSI), 2014, 289 (10), pp.7211-20. ⟨10.1074/jbc.M113.507046⟩. ⟨hal-01118312⟩
  • Corinne Buré, Philippe Marceau, Hervé Meudal, Agnès F Delmas. Synthesis and analytical investigation of C-terminally modified peptide aldehydes and ketone: application to oxime ligation.. Journal of Peptide Science, Wiley, 2012, 18 (3), pp.147-54. ⟨10.1002/psc.1429⟩. ⟨hal-00721799⟩
  • Chrystelle Derache, Hervé Meudal, Vincent Aucagne, Kevin J Mark, Martine Cadène, et al.. Initial insights into structure-activity relationships of avian defensins.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2012, 287 (10), pp.7746-55. ⟨10.1074/jbc.M111.312108⟩. ⟨hal-00721842⟩
  • Pedro da Silva, Isabelle Rahioui, Christian Laugier, Laurence Jouvensal, Hervé Meudal, et al.. Molecular requirements for the insecticidal activity of the plant peptide pea albumin 1 subunit b (PA1b).. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2010, 285 (43), pp.32689-94. ⟨10.1074/jbc.M110.147199⟩. ⟨hal-00591660⟩
  • Françoise Paquet, Karine Loth, Hervé Meudal, Francoise Culard, Daniel Genest, et al.. Refined solution structure and backbone dynamics of the archaeal MC1 protein. FEBS Journal, Wiley, 2010, 277 (24), pp.5133-5145. ⟨10.1111/j.1742-4658.2010.07927.x⟩. ⟨hal-00602469⟩
  • Yves Aubert, Marcel Chassignol, Victoria Roig, Gladys Mbemba, Julien Weiss, et al.. Synthesis and anti-HIV-1 integrase activity of modified dinucleotides. European Journal of Medicinal Chemistry, Elsevier, 2009, 44 (12), pp.5029-5044. ⟨10.1016/j.ejmech.2009.09.007⟩. ⟨hal-00521651⟩
  • Chrystelle Derache, Valérie Labas, Vincent Aucagne, Hervé Meudal, Céline Landon, et al.. Primary Structure and Antibacterial Activity of Chicken Bone Marrow-Derived beta-Defensins. Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2009, 53 (11), pp.4647-4655. ⟨10.1128/AAC.00301-09⟩. ⟨hal-00522326⟩
  • Thomas Chauvin, Philippe Durand, Michèle Bernier, Hervé Meudal, Bich-Thuy Doan, et al.. Detection of enzymatic activity by PARACEST MRI: a general approach to target a large variety of enzymes. Angewandte Chemie International Edition, Wiley-VCH Verlag, 2008, 47 (23), pp.4370-4372. ⟨10.1002/anie.200800809⟩. ⟨hal-00283242⟩
  • Y. Bilbille, F. Paquet, H. Meudal, M.J. Giraud-Panis, G. Lancelot. NMR studies of telomeric nucleoprotein complexes involving the Myb-like domain of the human telomeric protein TRF2. Comptes Rendus Chimie, Elsevier Masson, 2006, 9 (3-4), pp.452-458. ⟨10.1016/j.crci.2005.06.019⟩. ⟨hal-00088835⟩
  • Nelly Morellet, Hervé Meudal, Serge Bouaziz, Bernard Pierre Roques. Structure of the zinc finger domain encompassing residues 13–51 of the nucleocapsid protein from simian immunodeficiency virus. Biochemical Journal, Portland Press, 2006, 393 (3), pp.725-732. ⟨10.1042/BJ20051203⟩. ⟨hal-02122534⟩
  • Céline Landon, H. Meudal, Nathalie Boulanger, Philippe Bulet, Françoise Vovelle. Solution structures of stomoxyn and spinigerin, two insect antimicrobial peptides with an alpha-helical conformation. Biopolymers, Wiley, 2006, 81 (2), pp.92-103. ⟨10.1002/bip.20370⟩. ⟨hal-00088871⟩
  • Christine Anne, Armand Blommaert, Serge Turcaud, Anne-Sophie Martin, Hervé Meudal, et al.. Thio-derived disulfides as potent inhibitors of botulinum neurotoxin type B: implications for zinc interaction.. Bioorganic and Medicinal Chemistry, Elsevier, 2003, 11 (21), pp.4655-60. ⟨hal-02122201⟩
  • Christine Anne, Serge Turcaud, Jean Quancard, Franck Teffo, Hervé Meudal, et al.. Development of Potent Inhibitors of Botulinum Neurotoxin Type B. Journal of Medicinal Chemistry, American Chemical Society, 2003, 46 (22), pp.4648-4656. ⟨10.1021/jm0300680⟩. ⟨hal-02122278⟩
  • Nicolas Inguimbert, Pascale Coric, Hervé Poras, Hervé Meudal, Franck Teffot, et al.. Toward an optimal joint recognition of the S1' subsites of endothelin converting enzyme-1 (ECE-1), angiotensin converting enzyme (ACE), and neutral endopeptidase (NEP).. Journal of Medicinal Chemistry, American Chemical Society, 2002, 45 (7), pp.1477-86. ⟨hal-02122182⟩
  • H Chen, F Noble, A Mothé, H Meudal, P Coric, et al.. Phosphinic derivatives as new dual enkephalin-degrading enzyme inhibitors: synthesis, biological properties, and antinociceptive activities.. Journal of Medicinal Chemistry, American Chemical Society, 2000, 43 (7), pp.1398-408. ⟨hal-02122153⟩
  • B Bellier, M. Million, S Danascimento, H. Meudal, S Kellou, et al.. Replacement of glycine with dicarbonyl and related moieties in analogues of the C-terminal pentapeptide of cholecystokinin: CCK(2) agonists displaying a novel binding mode.. Journal of Medicinal Chemistry, American Chemical Society, 2000, 43 (20), pp.3614-23. ⟨hal-02122170⟩
  • S Druillennec, H Meudal, B.P Roques, M.C Fournié-Zaluski. Nucleomimetic strategy for the inhibition of HIV-1 nucleocapsid protein NCp7 activities.. Bioorganic and Medicinal Chemistry Letters, Elsevier, 1999, 9 (4), pp.627-32. ⟨hal-02122144⟩
  • Christelle David, Laurent Bischoff, Hervé Meudal, Aurélie Mothé, Nadia de Mota, et al.. Investigation of Subsite Preferences in Aminopeptidase A (EC 3.4.11.7) Led to the Design of the First Highly Potent and Selective Inhibitors of This Enzyme. Journal of Medicinal Chemistry, American Chemical Society, 1999, 42 (25), pp.5197-5211. ⟨10.1021/jm9903040⟩. ⟨hal-02385508⟩
  • Christelle David, Laurent Bischoff, Hervé Meudal, Aurélie Mothé, Nadia de Mota, et al.. Investigation of Subsite Preferences in Aminopeptidase A (EC 3.4.11.7) Led to the Design of the First Highly Potent and Selective Inhibitors of This Enzyme. Journal of Medicinal Chemistry, American Chemical Society, 1999, 42 (25), pp.5197-5211. ⟨10.1021/jm9903040⟩. ⟨hal-02122148⟩
  • Loïc Martin, Fabrice Cornille, Serge Turcaud, Hervé Meudal, Bernard Roques, et al.. Metallopeptidase Inhibitors of Tetanus Toxin: A Combinatorial Approach. Journal of Medicinal Chemistry, American Chemical Society, 1999, 42 (3), pp.515-525. ⟨10.1021/jm981066w⟩. ⟨hal-02528535⟩
  • B Bellier, S da Nascimento, H. Meudal, E. Gincel, B.P Roques, et al.. Novel constrained CCK-B dipeptoid antagonists derived from pipecolic acid.. Bioorganic and Medicinal Chemistry Letters, Elsevier, 1998, 8 (11), pp.1419-24. ⟨hal-02122133⟩
  • Christelle David, Laurent Bischoff, Hervé Meudal, Catherine Llorens-Cortes, Bernard Pierre Roques, et al.. Characterization and inhibition of aminopeptidase A by α-mercapto-β-amino acyl dipeptides. Letters in Peptide Science, Springer Verlag, 1997, 4 (4/6), pp.411-414. ⟨10.1023/A:1008894115205⟩. ⟨hal-02122127⟩
  • Bruno Bellier, Isabelle Mccort-Tranchepain, Bertrand Ducos, Sophie Danascimento, Hervé Meudal, et al.. Synthesis and Biological Properties of New Constrained CCK-B Antagonists: Discrimination of Two Affinity States of the CCK-B Receptor on Transfected CHO Cells. Journal of Medicinal Chemistry, American Chemical Society, 1997, 40 (24), pp.3947-3956. ⟨10.1021/jm970439a⟩. ⟨hal-02122116⟩
  • Laurent Bischoff, Christelle David, Loïc Martin, Hervé Meudal, Bernard-Pierre Roques, et al.. 2,4-Dinitrophenyl 4-Methoxybenzyl Disulfide: A New Efficient Reagent for the Electrophilic Sulfenylation of β-Amino Ester Enolates. Journal of Organic Chemistry, American Chemical Society, 1997, 62 (14), pp.4848-4850. ⟨10.1021/jo9623853⟩. ⟨hal-02122111⟩
  • Wang-Qing Liu, François Carreaux, Hervé Meudal, Bernard Roques, Christiane Garbay-Jaureguiberry. Synthesis of constrained 4-(phosphonomethyl)phenylalanine derivatives as hydrolytically stable analogs of O-phosphotyrosine. Tetrahedron, Elsevier, 1996, 52 (12), pp.4411-4422. ⟨10.1016/0040-4020(96)00085-3⟩. ⟨hal-02122054⟩
  • Pascale Coric, Serge Turcaud, Hervé Meudal, Bernard Pierre Roques, Marie-Claude Fournie-Zaluski. Optimal Recognition of Neutral Endopeptidase and Angiotensin-Converting Enzyme Active Sites by Mercaptoacyldipeptides as a Means To Design Potent Dual Inhibitors. Journal of Medicinal Chemistry, American Chemical Society, 1996, 39 (6), pp.1210-1219. ⟨10.1021/jm950590p⟩. ⟨hal-02122055⟩
  • Marie-Claude Fournie-Zaluski, Pascale Coric, Vincent Théry, Walter Gonzalez, Hervé Meudal, et al.. Design of Orally Active Dual Inhibitors of Neutral Endopeptidase and Angiotensin-Converting Enzyme with Long Duration of Action. Journal of Medicinal Chemistry, American Chemical Society, 1996, 39 (13), pp.2594-2608. ⟨10.1021/jm950783c⟩. ⟨hal-02122108⟩
  • C Guis, L Bruetschy, H. Meudal, B. Roques, G Gacel. Investigation of the structural parameters involved in the delta-opioid selectivity of several families of opioid peptides.. International Journal of Peptide and Protein Research, 1993, 41 (6), pp.576-86. ⟨hal-02122053⟩

Communication dans un congrès

  • H. Meudal, N. Guyot, K. Loth, G. Jousset, S. Trapp, et al.. Gga-AvBD11, the archetype of a new structural family of defensins. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02892790⟩
  • Nicolas Guyot, Hervé Meudal, Karine Loth, Guillaume Jousset, Anne Silvestre, et al.. 1ère structure 3D d’une défensine à double motif β-défensine, Gga-AvBD11 du poulet Gallus gallus, et explorations fonctionnelles. 5. Journées GDR MuFoPAM, Centre National de la Recherche Scientifique (CNRS). FRA., Oct 2018, Paris, France. ⟨hal-02788993⟩
  • Nicolas Guyot, Virginie Hervé, Hervé Meudal, Jean-Baptiste Madinier, Valérie Labas, et al.. Insights into the structure-function relationship of egg defensins. XIVth European Poultry Conference, World's Poultry Science Association (WPSA). INT., Jun 2014, Stavanger, Norway. ⟨hal-02743609⟩
  • Nicolas Guyot, Virginie Herve, Hervé Meudal, Jean-Baptiste Madinier, Valérie Labas, et al.. Functional and structural characterization of egg defensins. Banff Egg Forum, Jun 2014, Wroclaw, Poland. 12 diapositives. ⟨hal-02797356⟩
  • H. Meudal, Virginie Herve-Grepinet, Valérie Labas, A. Delmas, Yves Nys, et al.. 1ère défensine d'oeuf : caractérisation, synthèse, structure. 22. Congrès de la Société Française de Biophysique, Sep 2010, La Colle-sur-Loup, France. ⟨hal-02757482⟩
  • C Derache, H Meudal, V Aucagne, Anne-Christine Lalmanach, C Landon, et al.. Cys-containing functional miniproteins: synthesis and oxidative folding.. 2nd International Symposium on Antimicrobial Peptides - Food Veterinary Medical and Novel Applications., 2009, Saint-Malo, France. ⟨hal-02751660⟩
  • Chrystelle Derache, Hervé Meudal, Vincent Aucagne, Martine Cadène, Agnès Delmas, et al.. First insights into the structure-activity relationships of avian beta-defensins.. 2nd International Symposium on Antimicrobial Peptides - Food Veterinary Medical and Novel Applications., 2009, Saint-Malo, France. ⟨hal-02753345⟩
  • C Derache, H Meudal, V Aucagne, M Cadène, A Delmas, et al.. 1ère structure 3D d'une défensine antibactérienne de poulet. 21e Colloque Biotechnocentre, 2008, Seillac, France. ⟨hal-02752777⟩

Poster

  • A.F. Delmas, K. Loth, H. Meudal, V.P. Terrier, R.D. Rosa, et al.. NCL-based synthesis, 3D structure and first insight into antimicrobial properties of Cg-BigDef1, an oyster big defensin active at high salinity. 20e congrès annuel du Groupe Français des Peptides et des Protéines (GFPP), Mar 2017, Arcachon, France. ⟨hal-02894301⟩
  • A. F. Delmas, K. Loth, H. Meudal, V. P. Terrier, R. D. Rosa, et al.. NCL-based synthesis, 3D structure and first insight into antimicrobial properties of Cg-BigDef1, an oyster big defensin active at high salinity. 20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France. ⟨hal-02453263⟩
  • Marylène Bertrand, Hervé Meudal, Martine Decoville, Celine Landon. Prediction of Huntingon's Disease by Metabolomic NMR Analyzes: Studies in Drosophila Model. NMR: a tool for biology Xth, Jan 2017, Paris, France. ⟨hal-02453447⟩
  • A. Delmas, K. Loth, H. Meudal, V. Terrier, R.D. Rosa, et al.. NCL-based synthesis, 3D structure and first insight into antimicrobial properties of Cg-BigDef1, an oyster big defensin active at high salinity. NMR: a tool for Biology Xth, Jan 2017, Paris, France. ⟨hal-02453460⟩
  • Marylène Bertrand, H. Meudal, F. Borderes, V. Furstoss, L. Wozniak, et al.. Etude de la fertilité chez le bouc : analyse métabolique par RMN. 10e Journées du Réseau francophone de métabolomique et de fluxomique, May 2016, Montpellier, France. ⟨hal-02453355⟩
  • Marylène Bertrand, H. Meudal, M. Decoville, C. Landon. La RMN, un outil pour la métabolomique. 29e colloque Biotechnocentre, Oct 2016, Seillac, France. ⟨hal-02453360⟩
  • Virginie Hervé, Nicolas Guyot, H. Meudal, Valérie Labas, Sophie Rehault Godbert, et al.. Gallin is a chicken egg beta-defensin with a narrow antibacterial spectrum. 4. International Symposium on Antimicrobial Peptides, Jun 2014, Lorient, France. 1 p., 2014. ⟨hal-02793322⟩
  • H. Meudal, Chrystelle Derache, Virginie Herve-Grepinet, P. Bulet, Y. Le Maho, et al.. Avian defensins and ovo-defensins : a structural point of view. Antimicrobial Peptides. Discovery, Function and Application, Feb 2013, Ventura, CA, United States. 1 p., 2013. ⟨hal-02807466⟩
  • Mathieu Galibert, Chrystelle Derache, Franck Coste, Hervé Meudal, Anne-Christine Lalmanach, et al.. Improvement of the chemical production of β-defensins including straightforward attribution of disulfide bridges. 18. Réunion du GFPP, May 2013, Sète, France. 1 p., 2013. ⟨hal-02805308⟩
  • Hervé Meudal, Chrystelle Derache, Virginie Herve-Grepinet, Philippe Bulet, Yvon Le Maho, et al.. Birds defensins: a structural point of view. 25. ICMRBS - International Conference on Magnetic Resonance in Biological Systems, Aug 2012, Lyon, France. 1 p., 2012. ⟨hal-02808400⟩
  • Hervé Meudal, Chrystelle Derache, Virginie Herve-Grepinet, Philippe Bulet, Yvon Le Maho, et al.. 3D structures of avian defensins. 3. International Symposium on Antimicrobial Peptides: Today knowledge and future applications. (AMP 2012), Jun 2012, Lille, France. n.p., 2012. ⟨hal-02749392⟩
  • Chrystelle Derache, Emmanuel Kut, Hervé Meudal, Vincent Aucagne, Agnès Delmas, et al.. Antibacterial spectrum of avian defensin 2: peculiarities in relationship with structural features. 3. International Symposium on Antimicrobial Peptides: Today knowledge and future applications (AMP 2012), Jun 2012, Lille, France. pp.D-97, 2012. ⟨hal-02807349⟩
  • M. Galibert, Chrystelle Derache, F. Coste, H. Meudal, Anne-Christine Lalmanach, et al.. Improvement of the chemical production of β-defensins including straighforward attribution of disulfide bridges. 3. International Symposium on Antimicrobial Peptides: Today knowledge and future applications, Jun 2012, Lille, France. pp.C-43, 2012, AMP 2012 - Antimicrobial peptide symposium. ⟨hal-02748134⟩
  • H. Meudal, Virginie Herve-Grepinet, Valérie Labas, A. Delmas, Yves Nys, et al.. 1ère structure 3D d'une beta-défensine d'oeuf. GERM 2010 - Détection et Acquisition en Résonnance Magnétique, May 2010, Saint-Dié-des-Vosges, France. 1 p., 2010. ⟨hal-02816486⟩
  • Chrystelle Derache, Hervé Meudal, Vincent Aucagne, Anne-Christine Lalmanach, Céline Landon, et al.. Synthesis and oxidative folding of functional miniproteins containing three disulfide bridges. 21e Colloque Biotechnocentre, 2008, Seillac, France. 1 p, 2008. ⟨hal-02818274⟩