GARNIER Norbert

email : norbert.garnier@cnrs-orleans.fr

Phone : +33 2.38.25.76.68

Office D209

Lecturer within the thematic groupe “DNA repair: structure, fonction and dynamic

 



33 documents

Article dans une revue

  • Laurent Jacob, Paul Sawma, Norbert Garnier, Lionel A.T. Meyer, Justine Fritz, et al.. Inhibition of PlexA1-mediated brain tumor growth and tumor-associated angiogenesis using a transmembrane domain targeting peptide. Oncotarget, Impact journals, 2016, ⟨10.18632/oncotarget.11072⟩. ⟨hal-01407022⟩
  • Alexia Arpel, Paul Sawma, Caroline Spenlé, Justine Fritz, Lionel Meyer, et al.. Transmembrane Domain Targeting Peptide Antagonizing ErbB2/Neu Inhibits Breast Tumor Growth and Metastasis.. Cell Reports , Elsevier Inc, 2014, 8 (6), pp.1714-1721. ⟨10.1016/j.celrep.2014.07.044⟩. ⟨hal-01071710⟩
  • Widade Ziani, Antoine-P Maillard, Isabelle Petit-Härtlein, Norbert Garnier, Serge Crouzy, et al.. The X-ray structure of NccX from Cupriavidus metallidurans 31A illustrates potential dangers of detergent solubilization when generating and interpreting crystal structures of membrane proteins.. Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2014, 289 (45), pp.31160-31172. ⟨10.1074/jbc.M114.586537⟩. ⟨hal-01109416⟩
  • Samia Aci-Sèche, Paul Sawma, Pierre Hubert, James N. Sturgis, Dominique Bagnard, et al.. Transmembrane Recognition of the Semaphorin Co-Receptors Neuropilin 1 and Plexin A1 : Coarse-Grained Simulations. PLoS ONE, Public Library of Science, 2014, 9 (5), pp.e97779. ⟨10.1371/journal.pone.0097779⟩. ⟨hal-01175479⟩
  • Violette Senille, Dominique Lelievre, Françoise Paquet, Norbert Garnier, Ned Lamb, et al.. The addressing fragment of mitogaligin: first insights into functional and structural properties.. ChemBioChem, Wiley-VCH Verlag, 2013, 14 (6), pp.711-20. ⟨10.1002/cbic.201200715⟩. ⟨hal-00817503⟩
  • Norbert Garnier, Karine Loth, Franck Coste, Rafal Augustyniak, Virginie Nadan, et al.. An alternative flexible conformation of the E. coli HU beta(2) protein: structural, dynamics, and functional aspects. European Biophysics Journal, Springer Verlag (Germany), 2011, 40 (2), pp.117-129. ⟨10.1007/s00249-010-0630-y⟩. ⟨hal-00602370⟩
  • Samia Aci-Seche, Monique Genest, Norbert Garnier. Ligand entry pathways in the ligand binding domain of PPAR gamma receptor. FEBS Letters, Wiley, 2011, 585 (16), pp.2599-2603. ⟨10.1016/j.febslet.2011.07.014⟩. ⟨hal-00624897⟩
  • Samia Aci-Sèche, Norbert Garnier, Stéphane Goffinont, Daniel Genest, Spotheim-Maurizot Mélanie, et al.. Comparing native and irradiated E. coli lactose repressor-operator complex by molecular dynamics simulation. European Biophysics Journal, Springer Verlag (Germany), 2010, 39 (10), pp.1375-1384. ⟨10.1007/s00249-010-0591-1⟩. ⟨hal-00529210⟩
  • Samia Aci-Seche, Norbert Garnier, Daniel Genest, Stéphane Bourg, Christophe Marot, et al.. Molecular Dynamics Empirical Approach for Generating a Small Set of Structures Representative of the Internal Flexibility of a Receptor. QSAR & Combinatorial Science, 2009, 28 (9), pp.959-968. ⟨hal-00521647⟩
  • Oumarou Samna Soumana, Norbert Garnier, Monique Genest. Insight into the recognition patterns of the ErbB receptor family transmembrane domains: heterodimerization models through MD search. European Biophysics Journal, Springer Verlag (Germany), 2008, 37 (6), pp.851-864. ⟨10.1007/s00249-008-0293-0⟩. ⟨hal-00284330⟩
  • Daniel Genest, Norbert Garnier, Alban Arrault, Christophe Marot, Luc Morin-Allory, et al.. Ligand-escape pathways from the ligand-binding domain of PPAR gamma receptor as probed by molecular dynamics simulations. European Biophysics Journal, Springer Verlag (Germany), 2008, 37, pp.369-379. ⟨10.1007/s00249-007-0220-9⟩. ⟨hal-00512476⟩
  • Oumarou Samna Soumana, Norbert Garnier, Monique Genest. Molecular dynamics simulation approach for the prediction of transmembrane helix–helix heterodimers assembly. European Biophysics Journal, Springer Verlag (Germany), 2007, 36 (8), pp.1071-1082. ⟨10.1021/jm0702175 S0022-2623(07)00217-8⟩. ⟨hal-00166544⟩
  • Pierre Aller, Norbert Garnier, Monique Genest. Transmembrane Helix Packing of ErbB/Neu Receptor in Membrane Environment: A Molecular Dynamics Study. Journal of biomolecular structure & dynamics, 2006, 24 (3), pp.209-228. ⟨hal-00111939⟩
  • O. Samna Soumana, P. Aller, Norbert Garnier, M. Genest. Transmembrane peptides from tyrosine kinase receptor. Mutation-related behavior in a lipid bilayer investigated by molecular dynamics simulations. Journal of biomolecular structure & dynamics, 2005, 23, pp.91-100. ⟨hal-00088672⟩
  • P. Aller, L. Voiry, Norbert Garnier, M. Genest. Molecular dynamics (MD) investigations of preformed structures of the transmembrane domain of the oncogenic Neu receptor dimer in a DMPC bilayer. Biopolymers, Wiley, 2005, 77, pp.184-197. ⟨hal-00088475⟩
  • Norbert Garnier, Serge Crouzy, Monique Genest. Molecular Dynamics Simulations of the Transmembrane Domain of the Oncogenic ErbB2 Receptor Dimer in a DMPC Bilayer. Journal of Biomolecular Structure and Dynamics, Taylor & Francis: STM, Behavioural Science and Public Health Titles, 2003, 21 (2), pp.179-200. ⟨10.1080/07391102.2003.10506916⟩. ⟨hal-02123803⟩
  • Nicolas Sajot, Norbert Garnier, Monique Genest. Dimer models for ErbB-2/neu transmembrane domains from molecular dynamics simulations. Theoretical Chemistry Accounts: Theory, Computation, and Modeling, Springer Verlag, 1999, 101 (1-3), pp.67-72. ⟨10.1007/s002140050408⟩. ⟨hal-02123800⟩
  • J-P Duneau, S. Crouzy, Norbert Garnier, Y. Chapron, M Genest. Molecular dynamics simulations of the ErbB-2 transmembrane domain within an explicit membrane environment: comparison with vacuum simulations.. Biophysical Chemistry, Elsevier, 1999, 76 (1), pp.35-53. ⟨hal-02123801⟩
  • J-P Duneau, Norbert Garnier, G Cremel, G Nullans, P. Hubert, et al.. Time resolved fluorescence properties of phenylalanine in different environments. Comparison with molecular dynamics simulation.. Biophysical Chemistry, Elsevier, 1998, 73 (1-2), pp.109-19. ⟨hal-02123796⟩
  • Norbert Garnier, Daniel Genest, Jean Pierre Duneau, Monique Genest. Molecular modeling of c-erbB2 receptor dimerization: Coiled-coil structure of wild and oncogenic transmembrane domains—Stabilization by interhelical hydrogen bonds in the oncogenic form. Biopolymers, Wiley, 1997, 42 (2), pp.157-168. 3.0.CO;2-M">⟨10.1002/(SICI)1097-0282(199708)42:2<157::AID-BIP5>3.0.CO;2-M⟩. ⟨hal-02123792⟩
  • Jean-Pierre Duneau, Norbert Garnier, Monique Genest. Insight into Signal Transduction: Structural Alterations in Transmembrane Helices Probed by Multi-1 ns Molecular Dynamics Simulations. Journal of Biomolecular Structure and Dynamics, Taylor & Francis: STM, Behavioural Science and Public Health Titles, 1997, 15 (3), pp.555-572. ⟨10.1080/07391102.1997.10508966⟩. ⟨hal-02123789⟩
  • Norbert Garnier, D. Genest, M Genest. Correlated motions and propagation of the effect of a local conformational change in the transmembrane helix of the c-erb B2 encoded protein and its V659E mutant, studied by molecular dynamics simulations.. Biophysical Chemistry, Elsevier, 1996, 58 (3), pp.225-37. ⟨hal-02123788⟩
  • Norbert Garnier, Daniel Genest, Eric Hebert, Monique Genest. Influence of a Mutation in the Transmembrane Domain of the pl85 c- erb B2 Oncogene-Encoded Protein Studied by Molecular Dynamics Simulations. Journal of Biomolecular Structure and Dynamics, Taylor & Francis: STM, Behavioural Science and Public Health Titles, 1994, 11 (5), pp.983-1002. ⟨10.1080/07391102.1994.10508047⟩. ⟨hal-02123785⟩
  • Norbert Garnier, N. Ostrowsky. Brownian dynamics in a confined geometry. Experiments and numerical simulations. Journal de Physique II, EDP Sciences, 1991, 1 (10), pp.1221-1232. ⟨10.1051/jp2:1991129⟩. ⟨jpa-00247585⟩
  • N Ostrowsky, Norbert Garnier. Quasi-elastic light scattering from an evanescent wave to probe particle/wall interactions.. Biochemical Society Transactions, Portland Press, 1991, 19 (2), pp.500-1. ⟨hal-02123775⟩
  • Nicole Ostrowsky, Norbert Garnier, Didier Sornette. THE USE OF DYNAMIC LIGHT SCATTERING IN STUDIES OF VESICLES INTERACTIONS. Journal of Dispersion Science and Technology, Taylor & Francis, 1989, 10 (3), pp.277-284. ⟨10.1080/01932698908943176⟩. ⟨hal-02123769⟩

Communication dans un congrès

  • Justine Largillière, Rémy Le Meur, David Guiguène, Norbert Garnier, Celine Landon, et al.. Vers une description cinétique et structurale complète du mécanisme d'échange de chaînes de la protéine HU d'Escherichia coli.. GERM 2019, May 2019, Oléron, France. ⟨hal-02361645⟩

Poster

  • Justine Largillière, Rémy Le Meur, David Guinguène, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system.. Journée Fédération de recherche “Physique et Chimie du Vivant”, Apr 2019, Orléans, France. ⟨hal-02362578⟩
  • Justine Largillière, Rémy Le Meur, David Guinguène, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system.. NMR : a tool for biology XITh, Jan 2019, Paris, France. ⟨hal-02362588⟩
  • Justine Largillière, Rémy Le Meur, Norbert Garnier, Celine Landon, A.F. Delmas, et al.. Native and Intermediate conformations of the three HU dimers of E.coli.. XXVIII ICMRBS 2018, Aug 2018, Dublin, Ireland. ⟨hal-02362585⟩
  • Justine Largillière, Rémy Le Meur, David Guinguène, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system.. 31e colloque Biotechnocentre, Oct 2018, Seillac, France. ⟨hal-02362818⟩

Chapitre d'ouvrage

  • Norbert Garnier, D. Genest, M. Genest. Motions and correlations of the transmembrane domain of a protein receptor studied by molecular dynamics simulation. Nonlinear excitations in biomolecules, Springer Berlin Heidelberg, pp.241-246, 1994. ⟨hal-02123780⟩
  • N. Ostrowsky, Norbert Garnier. Brownian dynamics close to a wall, measured by quasi-elastic light scattering from an evanescent wave. Progress in colloid and polymer science, 84, Steinkopff, Heildberg, pp.371-376, 1991, Progress in Colloid & Polymer Science. ⟨hal-02123777⟩