Metabolomic Nuclear Magnetic Resonance Studies at Presymptomatic and Symptomatic Stages of Huntington’s Disease on a Drosophila Model

NMR studies show 16 metabolites discriminate symptomatic from presymptomatic stages in a Drosophila model of Huntington's disease. Potential biomarkers of the human disease?

Targeting the LINGO-1 receptor and its hetero-complexes: new therapeutic perspectives for the treatment of demyelinating and neurodegenerative diseases

CBM researchers in collaboration with INSERM U1195 (Kremlin-Bicêtre) have shown that the LINGO-1 receptor can form homo- and hetero-complexes with its homologs LINGO-2, LINGO-3 and LINGO-4 in the brain thus opening the way to new strategies to modulate their activity.

October 9th, 2020 - External seminar Dr Julien Robert-Paganin, Institut Curie, Paris

Pure and stable white light

Researchers from CBM and the University of Michigan used a lanthanide, dysprosium, to generate pure white light with no variation in hue.

Does your ten-year-old code still run?

Scientists increasingly rely on software, but software is fragile. How long can we expect our software to remain usable? Only practice can tell.

Impact of pesticides on health through diet

Publication of an article by Jean-Marc Bonmatin and his collaborators from the Task Force on Systemic Pesticides on the impact of pesticides on health through food, and on alternative agronomic solutions

Biotechnocentre Letter - July 2020

Cancellation of Biotechnocentre events in 2020

In favor of biodiversity

Solutions for the conservation and restoration of biodiversity

Creation of a predictive model of metabolic changes characteristic of neurodegenerative diseases

Researchers have created a predictive model based on the detection of changes in metabolite concentration resolved by ¹H high-resolution MAS NMR

Achille Le Bel Grand Prize awarded to Eva Jakab Toth

The Achille Le Bel Grand Prize, awarded by the Société Chimique de France, rewards internationally recognized works.

Disturbed expression of autophagy genes in blood of Parkinson's disease patients

A dysregulation in the expression of autophagy genes necessary for the elimination of neurotoxic protein aggregates, observed in Parkinson's disease, is also directly detectable in the blood of patients

Unveiling billion-year old life forms with X-ray vision

Synchrotron-based studies reveal unprecedented details of some of the most ancient traces of life in 3D. Fossilised bacteria 1.9 billion years old were imaged in situ in a fragment of rock by Ptychographic X-rays Computed Tomography documenting details of preservation not previously observed.

Organometallic networks for the near-infrared emission of lanthanides

A new approach to sensitize the near-infrared luminescence of lanthanides based on the use of the cavity of organometallic networks

Manganese: A double agent for imaging ?

Manganese is a biocompatible metal ion, with great interest for MRI and PET. The alliance between Mn2+ and a bispidine ligand leads to an unprecedented kinetic inertness, which might enable its in vivo use without any toxicity risk.