Organisation: Dpt Molecular, Structural and Chemical Biology

CASTAING Bertrand

email : bertrand.castaing[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.78.43

Research director, Leader of the Team  “Post-translational modifications of proteins and DNA repair: structure, function and dynamic”

 


87 documents

Article dans une revue45 documents

  • Franck Coste, Aanchal Mishra, Catherine Chapuis, Lucija Mance, Zofia Pukało, et al.. RING dimerisation drives higher-order organisation of SINA/SIAH E3 ubiquitin ligases. FEBS Journal, 2025, ⟨10.1111/febs.70000⟩. ⟨hal-04931763⟩
  • Ostiane d'Augustin, Virginie Gaudon, Capucine Siberchicot, Rebecca Smith, Catherine Chapuis, et al.. Identification of key residues of the DNA glycosylase OGG1 controlling efficient DNA sampling and recruitment to oxidized bases in living cells. Nucleic Acids Research, 2023, 51 (10), pp.4942-4958. ⟨10.1093/nar/gkad243⟩. ⟨hal-04088267v2⟩
  • Xhaferr Tanushi, Guillaume Pinna, Marie Vandamme, Capucine Siberchicot, Ostiane D’augustin, et al.. OGG1 competitive inhibitors show important off-target effects by directly inhibiting efflux pumps and disturbing mitotic progression. Frontiers in Cell and Developmental Biology, 2023, 11, pp.1124960. ⟨10.3389/fcell.2023.1124960⟩. ⟨hal-04016264⟩
  • Kiyoto Kamagata, Nanako Iwaki, Saori Kanbayashi, Trishit Banerjee, Rika Chiba, et al.. Structure-dependent recruitment and diffusion of guest proteins in liquid droplets of FUS. Scientific Reports, 2022, 12 (1), pp.7101. ⟨10.1038/s41598-022-11177-w⟩. ⟨hal-03927893⟩
  • Coste Franck, Stéphane Goffinont, Julien Cros, Virginie Gaudon, Guérin Martine, et al.. Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Research, 2022, ⟨10.1093/nar/gkac932⟩. ⟨hal-03841526⟩
  • Kiyoto Kamagata, Nanako Iwaki, Milan Kumar Hazra, Saori Kanbayashi, Trishit Banerjee, et al.. Molecular principles of recruitment and dynamics of guest proteins in liquid droplets. Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-98955-0⟩. ⟨hal-03433608⟩
  • Alan Wacquiez, Franck Coste, Emmanuel Kut, Virginie Gaudon, Sascha Trapp, et al.. Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1. Viruses, 2020, 12 (9), 25 p. ⟨10.3390/v12090947⟩. ⟨hal-03082436⟩
  • Charlotte Rieux, Stéphane Goffinont, Franck Coste, Zahira Tber, Julien Cros, et al.. Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights. International Journal of Molecular Sciences, 2020, 21 (6), pp.2058. ⟨10.3390/ijms21062058⟩. ⟨hal-03082414⟩
  • Karine Loth, Justine Largillière, Franck Coste, Françoise Culard, Céline Landon, et al.. New protein-DNA complexes in archaea: a small monomeric protein induces a sharp V-turn DNA structure. Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-50211-2⟩. ⟨hal-02306224⟩
  • Zahira Tber, Nicolas G. Biteau, Luigi Agrofoglio, Julien Cros, Stéphane Goffinont, et al.. Microwave-assisted Suzuki-Miyaura and Sonogashira coupling of 4-Chloro-2-(trifluoromethyl)pyrido[1,2-e]purine derivatives. European Journal of Organic Chemistry, 2019, 2019, pp.5756-5767. ⟨10.1002/ejoc.201900921⟩. ⟨hal-02347523⟩
  • Martine Beaufour, David Ginguené, Rémy Le Meur, Bertrand Castaing, Martine Cadène. Liquid Native MALDI Mass Spectrometry for the Detection of Protein-Protein Complexes. Journal of The American Society for Mass Spectrometry, 2018, 29 (10), pp.1981-1994. ⟨10.1007/s13361-018-2015-x⟩. ⟨hal-01965971⟩
  • Serge Boiteux, Franck Coste, Bertrand Castaing. Repair of 8-oxo-7,8-dihydroguanine in prokaryotic and eukaryotic cells: Properties and biological roles of the Fpg and OGG1 DNA N -glycosylases. Free Radical Biology and Medicine, 2017, 107, pp.179 - 201. ⟨10.1016/j.freeradbiomed.2016.11.042⟩. ⟨hal-01618166⟩
  • R. Le Meur, Françoise Culard, V. Nadan, S. Goffinont, F. Coste, et al.. The nucleoid-associated protein HU enhances 8-oxoguanine base excision by the formamidopyrimidine-DNA glycosylase. Biochemical Journal, 2015, 471 (1), pp.13-23. ⟨10.1042/BJ20150387⟩. ⟨hal-01216639⟩
  • F. d'Heygere, A. Schwartz, F. Coste, B. Castaing, M. Boudvillain. ATP-dependent motor activity of the transcription termination factor Rho from Mycobacterium tuberculosis. Nucleic Acids Research, 2015, 43 (12), pp.6099-60111. ⟨10.1093/nar/gkv505⟩. ⟨hal-01171219⟩
  • Rémy Le Meur, Karine Loth, Françoise Culard, Bertrand Castaing, Céline Landon. Backbone assignment of the three dimers of HU from Escherichia coli at 293 K: EcHUα2, EcHUβ2 and EcHUαβ. Biomolecular NMR Assignments, 2015, 9 (2), pp.359-363. ⟨10.1007/s12104-015-9610-6⟩. ⟨hal-01171467⟩
  • Françoise Paquet, Olivier Delalande, Stephane Goffinont, Françoise Culard, Karine Loth, et al.. Model of a DNA-protein complex of the architectural monomeric protein MC1 from Euryarchaea. PLoS ONE, 2014, 9 (2), pp.e88809. ⟨10.1371/journal.pone.0088809⟩. ⟨hal-01063974⟩
  • A. Biela, F. Coste, F. Culard, M. Guerin, S. Goffinont, et al.. Zinc finger oxidation of Fpg/Nei DNA glycosylases by 2-thioxanthine: biochemical and X-ray structural characterization. Nucleic Acids Research, 2014, 42 (16), pp.doi: 10.1093/nar/gku613. ⟨10.1093/nar/gku613⟩. ⟨hal-01175522⟩
  • Béatrice Matot, Yann-Vaï Le Bihan, Rachel Lescasse, Javier Pérez, Simona Miron, et al.. The orientation of the C-terminal domain of the Saccharomyces cerevisiae Rap1 protein is determined by its binding to DNA. Nucleic Acids Research, 2012, 40 (7), pp.3197-207. ⟨10.1093/nar/gkr1166⟩. ⟨hal-00720647⟩
  • Sylvie Baucheron, Franck Coste, Sylvie Canepa, Marie-Christine Maurel, Etienne Giraud, et al.. Binding of the RamR repressor to wild-type and mutated promoters of the RamA gene involved in efflux-mediated multidrug resistance in Salmonella enterica serovar Typhimurium.. Antimicrobial Agents and Chemotherapy, 2012, 56 (2), pp.942-8. ⟨10.1128/AAC.05444-11⟩. ⟨hal-00721770⟩
  • Yann Vei Le Bihan, Angeles M. Izquierdo, Franck Coste, Pierre Aller, Françoise Culard, et al.. 5-Hydroxy-5-methylhydantoin DNA lesion, a molecular trap for DNA glycosylases. Nucleic Acids Research, 2011, 39 (14), pp.6277-6290. ⟨10.1093/nar/gkr215⟩. ⟨hal-00614943⟩
  • Norbert Garnier, Karine Loth, Franck Coste, Rafal Augustyniak, Virginie Nadan, et al.. An alternative flexible conformation of the E. coli HU beta(2) protein: structural, dynamics, and functional aspects. European Biophysics Journal, 2011, 40 (2), pp.117-129. ⟨10.1007/s00249-010-0630-y⟩. ⟨hal-00602370⟩
  • Mathieu Creyssels, Éric Falcon, Bertrand Castaing. Scaling of ac electrical conductivity of powders under compression. Physical Review B: Condensed Matter and Materials Physics (1998-2015), 2008, 77 (7), pp.075135. ⟨10.1103/PhysRevB.77.075135⟩. ⟨hal-00264434⟩
  • Irina Gutsche, Andreja Vujicić-Zagar, Xavier Siebert, Pascale Servant, Françoise Vannier, et al.. Complex oligomeric structure of a truncated form of DdrA: A protein required for the extreme radiotolerance of Deinococcus.. Biochimica et Biophysica Acta - Molecular Cell Research, 2008, 1784 (7-8), pp.1050-8. ⟨10.1016/j.bbapap.2008.03.009⟩. ⟨hal-00297143⟩
  • Franck Coste, Matthias Ober, Yann-Vaï Le Bihan, Maria Angeles Izquierdo, Nadège Hervouet, et al.. Bacterial base excision repair enzyme Fpg recognizes bulky N7-substituted-FapydG lesion via unproductive binding mode.. Chemistry & Biology / Chemistry and Biology; CHEMISTRY & BIOLOGY, 2008, 15 (7), pp.706-17. ⟨10.1016/j.chembiol.2008.05.014⟩. ⟨hal-00408047⟩
  • Mathieu Creyssels, Stéphane Dorbolo, Alexandre Merlen, Claude Laroche, Bertrand Castaing, et al.. Some aspects of electrical conduction in granular systems of various dimensions. European Physical Journal E: Soft matter and biological physics, 2007, 23, pp.255. ⟨10.1140/epje/i2006-10186-9⟩. ⟨hal-00170319v3⟩
  • Marie Davídková, Viktorie Stísová, Stéphane Goffinont, Nathalie Gillard, Bertrand Castaing, et al.. Modification of DNA radiolysis by DNA-binding proteins: structural aspects. Radiation Protection Dosimetry, 2006, 122 (1-4), pp.100-105. ⟨10.1093/rpd/ncl442⟩. ⟨hal-00168743⟩
  • C. Buré, B. Castaing, C. Lange, A.F. Delmas. Location and base selectivity on fragmentation of brominated oligodeoxynucleotides. Journal of Mass Spectrometry, 2006, 41 (1), pp.84-90. ⟨10.1002/jms.967⟩. ⟨hal-00088837⟩
  • Stéphane Boiteux, Bertrand Castaing, J.P. Radicella. BER: (Base excision repair): molecular mechanisms and biological roles. Biofutur, 2006, 25 (271), pp.35-39. ⟨hal-00387927⟩
  • F. Coste, M. Ober, T. Carrell, S. Boiteux, C. Zelwer, et al.. Structural basis for the recognition of the FapydG lesion (2,6-diamino-4-hydroxy-5-formamidopyrimidine) by Formamidopyrimidine-DNA glycosylase. Journal of Biological Chemistry, 2006, 279 (42), pp.44074-44083. ⟨10.1074/jbc.M405928200⟩. ⟨hal-00114389⟩
  • K. Pereira de Jesus, L. Serre, C. Zelwer, B. Castaing. Structural insights into abasic site for Fpg specific binding and catalysis: comparative high-resolution crystallographic studies of Fpg bound to various models of abasic site analogues containing DNA. Nucleic Acids Research, 2005, 33, pp.5936-5944. ⟨hal-00088666⟩
  • Patricia Amara, Laurence Serre, B. Castaing, A. Thomas. Insights into the DNA repair process by the formamidopyrimidine-DNA glycosylase investigated by molecular dynamics. Journal of Biological Chemistry, 2004, 13 (8), pp.2009-2021. ⟨10.1110/ps.04772404⟩. ⟨hal-00088335⟩
  • N. Gillard, M. Bégusovà, B. Castaing, M. Spotheim-Maurizot. Radiation affects binding of Fpg repair protein to an abasic site containing DNA. Radiation Research, 2004, 162, pp.566-571. ⟨10.1667/RR3247⟩. ⟨hal-00113044⟩
  • E. Muller, D. Gasparutto, B. Castaing, A. Favier, J. Cadet. Recognition of cyclonucleoside lesions by the Lactococcus lactis FPG protein. Nucleosides, Nucleotides and Nucleic Acids, 2003, 22, pp.1563-1565. ⟨hal-00088198⟩
  • Charles Ramstein, Nadège Hervouet, Franck Coste, Charles Zelwer, Jacques Oberto, et al.. Evidence of a thermal unfolding dimeric intermediate for the Escherichia coli histone-like HU proteins: thermodynamics and structure.. Journal of Molecular Biology, 2003, 331 (1), pp.101-21. ⟨hal-02127656⟩
  • Laurence Serre, Karine Pereira de Jésus, Serge Boiteux, Charles Zelwer, Bertrand Castaing. Crystal structure of the Lactococcus lactis formamidopyrimidine-DNA glycosylase bound to an abasic site analogue-containing DNA. EMBO Journal, 2002, 21 (12), pp.2854-2865. ⟨10.1093/emboj/cdf304⟩. ⟨hal-02141118⟩
  • Karine Pereira de Jésus, Laurence Serre, Nadège Hervouet, Véronique Bouckson-Castaing, Charles Zelwer, et al.. Crystallization and preliminary X-ray crystallographic studies of a complex between the Lactococcus lactis Fpg DNA-repair enzyme and an abasic site containing DNA. Acta crystallographica Section D : Structural biology [1993-..], 2002, 58 (4), pp.679-682. ⟨10.1107/S0907444902001397⟩. ⟨hal-02141124⟩
  • N Guibourt, Bertrand Castaing, P van Der Kemp, S. Boiteux. Catalytic and DNA binding properties of the ogg1 protein of Saccharomyces cerevisiae: comparison between the wild type and the K241R and K241Q active-site mutant proteins.. Biochemistry, 2000, 39 (7), pp.1716-24. ⟨hal-02141126⟩
  • Bertrand Castaing, Jean-Louis Fourrey, Nadege Hervouet-Coste, Martial Thomas, Serge Boiteux, et al.. AP site structural determinants for Fpg specific recognition. Nucleic Acids Research, 1999, 27 (2), pp.608-615. ⟨10.1093/nar/27.2.608⟩. ⟨hal-02141144⟩
  • Franck Coste, N. Hervouet, J. Oberto, C. Zelwer, Bertrand Castaing. Crystallization and preliminary X-ray diffraction analysis of the homodimeric form alpha2 of the HU protein from Escherichia coli.. Acta crystallographica Section D : Structural biology [1993-..], 1999, 55 (Pt 11), pp.1952-4. ⟨hal-02127644⟩
  • Martial Thomas, Bertrand Castaing, Jean-Louis Fourrey, Charles Zelwer. Synthesis of an Enantiomerically Pure Carbocyclic DNA Abasic Site Analogue. Nucleosides, Nucleotides and Nucleic Acids, 1999, 18 (2), pp.239-243. ⟨10.1080/15257779908043071⟩. ⟨hal-02141150⟩
  • Bertrand Castaing, Charles Zelwer, Jacques Laval, Serge Boiteux. HU Protein of Escherichia coli Binds Specifically to DNA That Contains Single-strand Breaks or Gaps. Journal of Biological Chemistry, 1995, 270 (17), pp.10291-10296. ⟨10.1074/jbc.270.17.10291⟩. ⟨hal-02141159⟩
  • T.R O'Connor, R.J Graves, G. de Murcia, Bertrand Castaing, J Laval. Fpg protein of Escherichia coli is a zinc finger protein whose cysteine residues have a structural and/or functional role.. Journal of Biological Chemistry, 1993, 268 (12), pp.9063-70. ⟨hal-02141187⟩
  • Bertrand Castaing, Albert Geiger, Hartmut Seliger, Peter Nehls, Jacques Laval, et al.. Cleavage and binding of a DNA fragment containing a single 8-oxoguanine by wild type and mutant FPG proteins. Nucleic Acids Research, 1993, 21 (12), pp.2899-2905. ⟨10.1093/nar/21.12.2899⟩. ⟨hal-02141167⟩
  • Bertrand Castaing, Serge Boiteux, Charles Zelwer. DNA containing a chemically reduced apurinic site is a high affinity ligand for the E.coli formamidopyrimidine-DNA glycosyiase. Nucleic Acids Research, 1992, 20 (3), pp.389-394. ⟨10.1093/nar/20.3.389⟩. ⟨hal-02141191⟩
  • W Zagorski, Bertrand Castaing, C.J Herbert, M Labouesse, R Martin, et al.. Purification and characterization of the Saccharomyces cerevisiae mitochondrial leucyl-tRNA synthetase.. Journal of Biological Chemistry, 1991, 266 (4), pp.2537-41. ⟨hal-02141199⟩

Communication dans un congrès7 documents

  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. Architecture et dynamique de protéines histone-like de bactérie et d’archées. Journée BioRMN IdF, Sep 2020, Gif-sur-Yvette, France. ⟨hal-03053296⟩
  • Bertrand Castaing. Inhibition des ADN glycosylases de la super famille structurale Fpg/Nei par des thiopurines: relations structure-activité. Journée scientifique de la Fédération de Recherche 2708, Apr 2019, Orléans, France. ⟨hal-02903112⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. Vers une description cinétique et structurale complète du mécanisme d'échange de chaînes de la protéine HU d'Escherichia coli.. XXXIe congrès du GERM (Groupement d'Etudes de Résonance Magnétique), May 2019, Oléron, France. ⟨hal-02361645⟩
  • Bertrand Castaing. Les ADN glycosylases qui initient le système de réparation de l'ADN par excision de base, de nouvelles cibles potentielles pour lutter contre le cancer. Colloque du Réseau « Molécules marines, métabolisme et cancer » du Canréropôle Grand Ouest, May 2019, Mansigné, France. ⟨hal-02903074⟩
  • J. Cros, F. Coste, S. Goffinont, Virginie Nadan, V. Roy, et al.. Discovery and characterization of inhibitors of the DNA repair enzymes hNEIL1 and hOGG1, pertinent therapeutic targets for cancer therapy. Laboratoire International Associé, Jun 2019, Varsovie, Poland. ⟨hal-02903108⟩
  • J. Cros, F. Coste, Z. Tber, S. Goffinont, Virginie Nadan, et al.. Small molecule inhibitors of the human DNA glycosylases hOGG1 and NEIL1, pertinent therapeutic targets in cancer and neurodegenerative disease therapies. 25th Young Research Fellows Meeting, Mar 2018, Orléans, France. ⟨hal-02903084⟩
  • Daniel Marc, Franck Coste, Bertrand Castaing. Des cristaux pour la recherche de nouveaux antiviraux. Journées d'Animation Scientifique de la Fédération de Recherche d'Infectiologie (FéRI), Oct 2015, Orléans, France. 17 diapositives. ⟨hal-02792217⟩

Poster32 documents

  • Aanchal Mishra, Franck Coste, Bertrand Castaing, Sebastien Huet, Marcin J Suskiewicz. Higher-order multimerisation of a ubiquitin E3 ligase: the case of SIAH1. 3ème Journée de Biologie Structurale Intégrative Paris-Saclay (BSI@Paris-Saclay 2024), Nov 2024, Paris, France. ⟨hal-05216446⟩
  • Lucija Mance, Nicolas Bigot, Edison Zhamungui Sánchez, Franck Coste, Natalia Martín-González, et al.. Studies of BTB domain polymerisation through integrative structural biology. FRISBI User Meeting 2024, CNRS campus Gif-sur-Yvette, Jan 2024, Gif sur Yvette, France. ⟨hal-04778726⟩
  • Lucija Mance, Franck Coste, Sébastien Huet, Bertrand Castaing, Marcin Jozef Józef Suskiewicz. Dynamic BTB domain filaments promote clustering of ZBTB proteins. EMBO Meeting Ubiquitin and ubiquitin-like proteins in health and disease, Sep 2024, Cavtat & Dubrovnik, France. ⟨hal-05216344⟩
  • Stéphane Goffinont, Pierre Prieu-Serandon, Lucija Mance, Virginie Gaudon, Norbert Garnier, et al.. Structural insights into the regulation of the human E2-SUMO conjugate through analysis of its stable mimetic. Ubiquitin and Friends, Apr 2023, Wien, Austria, France. ⟨hal-05216360⟩
  • Daniel Marc, Alan Wacquiez, Stéphane Goffinont, Virginie Nadan, Franck Coste, et al.. Interaction de la protéine NS1 des virus influenza A avec l’ARN : mécanismes impliqués dans la reconnaissance spécifique. XIIes Journées Francophones de Virologie, Mar 2019, Lyon, France. Virologie, 23, 2019. ⟨hal-02737761⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system. NMR : a tool for biology XITh, Jan 2019, Paris, France. ⟨hal-02362588⟩
  • Julien Cros, Franck Coste, Stéphane Goffinont, Virginie Nadan, Norbert Garnier, et al.. Screening, characterization and structural studies of small molecules inhibitors of the DNA glycosylase hNEIL1 and hOGG1, potential therapeutic targets in cancer and neurodegenerative disease. 1st French congress on Integrative Structural Biology (BSI-2019), Oct 2019, Toulouse, France. ⟨hal-03385201⟩
  • J. Cros, F. Coste, S. Goffinont, V. Gaudon, V. Roy, et al.. Search for small molecule inhibitors of the DNA repair enzymes hNEIL1 and hOGG1, potential therapeutic targets in cancer. Journée Fédération de recherche “Physique et Chimie du Vivant” FR2708 (CBM/ICOA), Apr 2019, Orléans, France. ⟨hal-02903223⟩
  • J. Cros, F. Coste, S. Goffinont, V. Gaudon, V. Roy, et al.. Search for small molecule inhibitors of the DNA repair enzymes hNEIL1 and hOGG1, potential therapeutic targets in cancer. 13th French 3R meeting, May 2019, Presqu’île de Giens, France. ⟨hal-02903219⟩
  • F. Coste, G. Chaume, J.-B. Madinier, I. Rahioui, B. Castaing, et al.. Incorporation of trifluoromethylated pseudoproline in an entomotoxic knottin: effects on oxidative folding, 3D structure and biological activity. 21e congrès du Groupe Français des Peptides et des Protéines (GFPP), May 2019, Amboise, France. ⟨hal-02893471⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system.. Journée Fédération de recherche “Physique et Chimie du Vivant”, Apr 2019, Orléans, France. ⟨hal-02362578⟩
  • J. Cros, F. Coste, S. Goffinont, V. Gaudon, V. Roy, et al.. Recherche d’inhibiteurs des enzymes de réparation de l’ADN hNeil1 et hOGG1, de nouvelles cibles pertinentes pour le développement de thérapies anticancéreuses. 31e colloque Biotechnocentre, Oct 2018, Seillac, France. ⟨hal-02904682⟩
  • Alan Wacquiez, Franck Coste, Caroline Blondeau, Emmanuel Kut, Virginie Nadan, et al.. NS1 des virus Influenza A : approches structurales et fonctionnelles pour de nouvelles stratégies anti-virales. 20. Journées Francophones de Virologie 2018, Mar 2018, Paris, France. John Libbey Eurotext, Virologie, 22, 148 p., 2018. ⟨hal-02736544⟩
  • Justine Largillière, Rémy Le Meur, Norbert Garnier, Celine Landon, A.F. Delmas, et al.. Native and Intermediate conformations of the three HU dimers of E.coli.. 28th ICMRBS - International Council on Magnetic Resonance in Biological Systems, Aug 2018, Dublin, Ireland. ⟨hal-02362585⟩
  • J. Cros, F. Coste, Z. Tber, S. Goffinont, V. Nadan, et al.. Search for small molecule inhibitors of DNA glycosylases, pertinent therapeutic targets in cancer and neurodegenerative disease therapies. 5e Colloque annuel du Laboratoire International Associé (LIA) MiR-TANGo, May 2018, Orléans, France. ⟨hal-02904701⟩
  • F. Coste, G. Chaume, J.-B. Madinier, I. Rahioui, B. Castaing, et al.. Incorporation of trifluoromethylated pseudoproline in an entomotoxic knottin: effects on oxidative folding, 3D structure and biological activity. 35th European Peptide Symposium (EPS35), Aug 2018, Dublin, Ireland. ⟨hal-02894161⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Celine Landon, A.F. Delmas, et al.. First kinetics description of the EcHU chain exchange system.. 28th ICMRBS - International Council on Magnetic Resonance in Biological Systems, Aug 2018, Dublin, Ireland. ⟨hal-02362586⟩
  • Karine Loth, Justine Largillière, Franck Coste, Françoise Culard, Celine Landon, et al.. New protein-DNA complexes in archaea: a small monomeric protein induces a sharp V-turn DNA structure.. EuroMar 2018, Jul 2018, Nantes, France. ⟨hal-02362581⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system.. 31e colloque Biotechnocentre, Oct 2018, Seillac, France. ⟨hal-02362818⟩
  • Justine Largillière, Rémy Le Meur, Martine Cadene, Bertrand Castaing, Karine Loth, et al.. Premières études cinétiques du mécanisme d’échange de chaînes de la protéine HU d’Escherischia coli.. 16e colloque scientifique de l’ADOC : Converger pour Renforcer, Apr 2018, Orléans, France. ⟨hal-02362579⟩
  • Alan Wacquiez, Stéphane Goffinont, Virginie Nadan, Franck Coste, Emmanuel Kut, et al.. Structures et fonctions de la protéine NS1 des virus influenza pour la recherche de nouvelles cibles thérapeutiques. 31e Colloque Biotechnocentre, Oct 2018, Seillac, France. , 2018. ⟨hal-02736195⟩
  • Karine Loth, Justine Largillière, Franck Coste, Françoise Culard, Bertrand Castaing, et al.. New protein-DNA complexes in archaea: a small monomeric protein induces a V-turn structure.. 28th ICMRBS - International Council on Magnetic Resonance in Biological Systems, Aug 2018, Dublin, Ireland. ⟨hal-02362584⟩
  • Karine Loth, Françoise Culard, Justine Largillière, Celine Landon, Bertrand Castaing, et al.. New protein-DNA complexes in archaea: a monomeric protein induces a U-turn structure.. 5e séminaire scientifique du LIA MiR-TANGo, May 2018, Orléans, France. ⟨hal-02362804⟩
  • Justine Largillière, Rémy Le Meur, Martine Cadene, Bertrand Castaing, Karine Loth, et al.. Premières études cinétiques du mécanisme d’échange de chaînes de la protéine HU d’Escherischia coli.. Journée Fédération de recherche “Physique et Chimie du Vivant”, Jan 2018, Orléans, France. ⟨hal-02362577⟩
  • A. Wacquiez, S. Goffinont, V. Nadan, F. Coste, E. Kut, et al.. NS1 des virus influenza : relations structure-fonction pour la recherche de nouveaux anti-viraux. 30e colloque Biotechnocentre, Oct 2017, Seillac, France. ⟨hal-02904785⟩
  • A. Wacquiez, F. Coste, C. Blondeau, E. Kut, V. Nadan, et al.. NS1 des virus Influenza A : approches structurales et fonctionnelles pour de nouvelles stratégies anti-virales. Le Studium Conférence « Messenger RNA therapeutics : advances and perspectives », Mar 2017, Orléans, France. ⟨hal-02904828⟩
  • Karine Loth, Justine Largillière, Franck Coste, A.F. Delmas, Bertrand Castaing, et al.. New protein-DNA complexes in archaea: a monomeric protein induces a U-turn structure.. Le Studium Confenrence: Structural biology and biophysics of RNA-protein complexes, Nov 2017, Orléans, France. ⟨hal-02362576⟩
  • A. Wacquiez, F. Coste, V. Nadan, E. Kut, S. Goffinont, et al.. NS1 of Influenza viruses: structural and functional approaches towards the discovery of novel anti-influenza drugs. Le Studium Conférence “Structural Biology and biophysics of RNA-protein complexes”, Nov 2017, Orléans, France. ⟨hal-02904778⟩
  • Karine Loth, Françoise Culard, Justine Largillière, Celine Landon, Bertrand Castaing, et al.. The MC1-DNA complex solution structure reveals that a monomeric protein can induce a U-turn in archaea.. NMR: a tool for biology XTh, Jan 2017, Paris, France. ⟨hal-02361613⟩
  • Justine Largillière, Rémy Le Meur, Martine Cadene, Bertrand Castaing, Karine Loth, et al.. Première description cinétique du mécanisme d’échange de chaînes de la protéine HU d'Escherichia coli.. 30e colloque Biotechnocentre, Oct 2017, Seillac, France. ⟨hal-02361632⟩
  • C. Rieux, F. Coste, F. Culard, S. Goffinont, S. Bourg, et al.. Small-molecule inhibitors of Fpg/Nei DNA glycosylases, enzymes initiating the base excision repair pathway, new targets for cancer therapy. XXII International Roundtable on Nucleosides, Nucleotides and Nucleic Acids, Jul 2016, Paris, France. ⟨hal-02919151⟩
  • Mathieu Galibert, Chrystelle Derache, Franck Coste, Hervé Meudal, Anne-Christine Lalmanach, et al.. Improvement of the chemical production of β-defensins including straightforward attribution of disulfide bridges. 18. Réunion du GFPP, May 2013, Sète, France. 1 p., 2013. ⟨hal-02805308⟩

Ouvrage (y compris édition critique et traduction)1 document

  • Kadija Essalhi, L. Gellon, Julie Berthault, Françoise Culard, Martine Guerin, et al.. Ogg1, a Saccharomyces cerevisiae bifunctional DNA glycosylase involved in base excision repair of oxidative DNA damage, interacts with the replicative DNA polymerase, Pol epsilon. pp.409, 2011. ⟨hal-00614891⟩

Chapitre d'ouvrage2 documents

  • F. d'Heygère, A. Schwartz, F. Coste, B. Castaing, M. Boudvillain. Monitoring RNA Unwinding by the Transcription Termination Factor Rho from Mycobacterium tuberculosis. Methods in Mecular Biology, 1259, Springer, pp.293-311, 2015, RNA remodelling proteins (Boudvillain, ed), 978-1-4939-2213-0. ⟨10.1007/978-1-4939-2214-7_18⟩. ⟨hal-01174055⟩
  • Evelyne Sage, Bertrand Castaing. Radiation damage to biomolecules, radioprotection and radiotherapy. Genome maintenance mechanisms in response to radiation-induced DNA damage. Mélanie Spotheim-Maurizot. Radiation chemistry from basics to applications in material and life sciences, EDP Sciences, pp.219-232, 2008. ⟨hal-00284342⟩

Documents récupérés de l'archive ouverte HAL logo

 

CADÈNE Martine

email : martine.cadene[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.56.24

Research director, leader of the team “Functional Mass Spectrometry of molecular assemblies”


80 documents

Article dans une revue48 documents

  • Fanny Ruhland, Guillaume Gabant, Timothée Toussaint, Matej Nemcic, Martine Cadène, et al.. Reproductives signature revealed by protein profiling and behavioral bioassays in termite. Scientific Reports, 2023, 13 (1), pp.7070. ⟨10.1038/s41598-023-33252-6⟩. ⟨hal-04090025⟩
  • Guillaume Gabant, Martin Stekovic, Matej Nemcic, Justine Pinêtre, Martine Cadene. A sDOE (simple design-of-experiment) approach for parameter optimization in mass spectrometry. Part 1. Parameter selection and interference effects in topdown ETD fragmentation of proteins in a UHR-QTOF instrument.. Journal of The American Society for Mass Spectrometry, 2023, 34 (1), pp.27-35. ⟨10.1021/jasms.2c00215⟩. ⟨hal-03871364⟩
  • Koffi N'Guessan, Renata Grzywa, Seda Seren, Guillaume Gabant, Maria Juliano, et al.. Human proteinase 3 resistance to inhibition extends to alpha-2 macroglobulin. FEBS Journal, 2020, ⟨10.1111/febs.15229⟩. ⟨hal-02901768⟩
  • Artur Castro-Rodrigues, Yaxian Zhao, Fátima Fonseca, Guillaume Gabant, Martine Cadène, et al.. The Interaction between the Drosophila EAG Potassium Channel and the Protein Kinase CaMKII Involves an Extensive Interface at the Active Site of the Kinase. Journal of Molecular Biology, 2018, 430 (24), pp.5029-5049. ⟨10.1016/j.jmb.2018.10.015⟩. ⟨hal-01966024⟩
  • Martine Beaufour, David Ginguené, Rémy Le Meur, Bertrand Castaing, Martine Cadène. Liquid Native MALDI Mass Spectrometry for the Detection of Protein-Protein Complexes. Journal of The American Society for Mass Spectrometry, 2018, 29 (10), pp.1981-1994. ⟨10.1007/s13361-018-2015-x⟩. ⟨hal-01965971⟩
  • Guillaume Gabant, Alain Boyer, Martine Cadene. SSPaQ: A Subtractive Segmentation Approach for the Exhaustive Parallel Quantification of the Extent of Protein Modification at Every Possible Site. Journal of The American Society for Mass Spectrometry, 2016, 27 (8), pp.1328 - 1343. ⟨10.1007/s13361-016-1416-y⟩. ⟨hal-01406961⟩
  • Maria joão Marques-Carvalho, Johannes Oppermann, Eva Muñoz, Andreia s. Fernandes, Guillaume Gabant, et al.. Molecular Insights into the Mechanism of Calmodulin Inhibition of the EAG1 Potassium Channel. Structure, 2016, 24 (10), pp.1742 - 1754. ⟨10.1016/j.str.2016.07.020⟩. ⟨hal-01407944⟩
  • Brian T. Chait, Martine Cadene, Paul Dominic Olinares, Michael P. Rout, Yi Shi. Revealing Higher Order Protein Structure Using Mass Spectrometry. Journal of The American Society for Mass Spectrometry, 2016, 27 (6), pp.952 - 965. ⟨10.1007/s13361-016-1385-1⟩. ⟨hal-01405849⟩
  • Iván O. Rivera-Torres, Tony B. Jin, Martine Cadene, Brian T. Chait, Sébastien F. Poget. Discovery and characterisation of a novel toxin from Dendroaspis angusticeps, named Tx7335, that activates the potassium channel KcsA. Scientific Reports, 2016, 6, pp.23904. ⟨10.1038/srep23904⟩. ⟨hal-01407683⟩
  • Marylène Bertrand, Annie Chabin, Cyril Colas, Martine Cadène, Didier Chaput, et al.. The AMINO experiment: exposure of amino acids in the EXPOSE-R experiment on the International Space Station and in laboratory. International Journal of Astrobiology, 2015, 14 (01), pp.89-97. ⟨10.1017/S1473550414000354⟩. ⟨hal-01170486⟩
  • Alexandre Morel, Caroline Teyssier, Jean-François Trontin, Kateřina Eliášová, Bedřich Pešek, et al.. Early molecular events involved in Pinus pinaster Ait. somatic embryo development under reduced water availability: transcriptomic and proteomic analyses. Physiologia Plantarum, 2014, 152 (1), pp.184-201. ⟨10.1111/ppl.12158⟩. ⟨hal-01179486⟩
  • C. Guarino, M. Legowska, C. Epinette, C. Kellenberger, Sandrine Dallet-Choisy, et al.. New Selective Peptidyl Di(chlorophenyl) Phosphonate Esters for Visualizing and Blocking Neutrophil Proteinase 3 in Human Diseases. Journal of Biological Chemistry, 2014, 289 (46), pp.doi: 10.1074/jbc.M114.591339. ⟨10.1074/jbc.M114.591339⟩. ⟨hal-01179111⟩
  • Alexandre Morel, Jean-François Trontin, Françoise Corbineau, Anne-Marie Lomenech, Martine Beaufour, et al.. Cotyledonary somatic embryos of Pinus pinaster Ait. most closely resemble fresh, maturing cotyledonary zygotic embryos: biological, carbohydrate and proteomic analyses.. Planta, 2014, 240 (5), pp.1075-1095. ⟨10.1007/s00425-014-2125-z⟩. ⟨hal-01179478⟩
  • Nicolas Bouchet, Jerome Jaillet, Guillaume Gabant, Benjamin Brillet, Luis Briseño-Roa, et al.. cAMP protein kinase phosphorylates the Mos1 transposase and regulates its activity: evidences from mass spectrometry and biochemical analyses. Nucleic Acids Research, 2014, 42 (2), pp.1117-1128. ⟨10.1093/nar/gkt874⟩. ⟨hal-02132866⟩
  • Caroline Teyssier, Stéphane Maury, Martine Beaufour, Cécile Grondin, Alain Delaunay, et al.. In search of markers for somatic embryo maturation in hybrid larch ( Larix × eurolepis ): global DNA methylation and proteomic analyses. Physiologia Plantarum, 2014, 150 (2), pp.271-291. ⟨10.1111/ppl.12081⟩. ⟨hal-02087600⟩
  • Martine Beaufour, Fabienne Godin, Béatrice Vallée, Martine Cadene, Hélène Bénédetti. Interaction Proteomics Suggests a New Role for the Tfs1 Protein in Yeast.. Journal of Proteome Research, 2012, 11 (6), pp.3211-3218. ⟨10.1021/pr201239t⟩. ⟨hal-00721771⟩
  • Laurette Tavel, Lucie Jaquillard, Andreas I Karsisiotis, Fabienne Saab, Laurence Jouvensal, et al.. Ligand binding study of human PEBP1/RKIP: interaction with nucleotides and Raf-1 peptides evidenced by NMR and mass spectrometry.. PLoS ONE, 2012, 7 (4), pp.e36187. ⟨10.1371/journal.pone.0036187⟩. ⟨hal-00726284⟩
  • Christophe Epinette, Cécile Croix, Lucie Jaquillard, Sylvain Marchand-Adam, Christine Kellenberger, et al.. A selective reversible azapeptide inhibitor of human neutrophil proteinase 3 derived from a high affinity FRET substrate.. Biochemical Pharmacology, 2012, 83 (6), pp.788-96. ⟨10.1016/j.bcp.2011.12.023⟩. ⟨hal-00721854⟩
  • Chrystelle Derache, Christophe Epinette, Alain Roussel, Guillaume Gabant, Martine Cadene, et al.. Crystal structure of greglin, a novel non-classical Kazal inhibitor, in complex with subtilisin.. FEBS Journal, 2012, 279 (24), pp.4466-78. ⟨10.1111/febs.12033⟩. ⟨hal-00817089⟩
  • Maria J Marques-Carvalho, Nirakar Sahoo, Frederick W Muskett, Ricardo S Vieira-Pires, Guillaume Gabant, et al.. Structural, Biochemical, and Functional Characterization of the Cyclic Nucleotide Binding Homology Domain from the Mouse EAG1 Potassium Channel.. Journal of Molecular Biology, 2012, 423 (1), pp.34-46. ⟨10.1016/j.jmb.2012.06.025⟩. ⟨hal-00747621⟩
  • Lucie Jaquillard, Fabienne Saab, Françoise Schoentgen, Martine Cadene. Improved accuracy of low affinity protein-ligand equilibrium dissociation constants directly determined by electrospray ionization mass spectrometry.. Journal of The American Society for Mass Spectrometry, 2012, 23 (5), pp.908-22. ⟨10.1007/s13361-011-0305-7⟩. ⟨hal-00726223⟩
  • Chrystelle Derache, Hervé Meudal, Vincent Aucagne, Kevin J Mark, Martine Cadène, et al.. Initial insights into structure-activity relationships of avian defensins.. Journal of Biological Chemistry, 2012, 287 (10), pp.7746-55. ⟨10.1074/jbc.M111.312108⟩. ⟨hal-00721842⟩
  • Guillaume Gabant, Martine Cadène. Mass spectrometry of full-length integral membrane proteins to define functionally relevant structural features. Methods, 2008, 46, pp.54-61. ⟨10.1016/j.ymeth.2008.10.021⟩. ⟨hal-00512469⟩
  • Corinne Buré, Stéphane Goffinont, Agnès F. Delmas, Martine Cadene, Françoise Culard. Oxidation-sensitive residues mediate the DNA-bending activity of MC1 protein. Journal of Molecular Biology, 2008, 376 (1), pp.120-130. ⟨10.1016/j.jmb.2007.11.057⟩. ⟨hal-00283220⟩
  • Mélanie Spotheim-Maurizot, Sonia Mazier, Sandrine Villette, Stéphane Goffinont, Dominique Genest, et al.. Radiationinduced oxidation of proteins in DNA-protein complexes. Radioprotection, 2008, 43 (5), pp.131-132. ⟨10.1051/radiopro:2008526⟩. ⟨hal-00527448⟩
  • David Fenyo, Qingjun Wang, Jeffrey Degrasse, Julio Padovan, Martine Cadène, et al.. MALDI Sample Preparation: the Ultra Thin Layer Method. Journal of visualized experiments : JoVE, 2007, 3, pp.192. ⟨10.3791/192⟩. ⟨hal-02150127⟩
  • Vanessa Bourgeaux, Martine Cadene, Friedrich Piller, Véronique Piller. Efficient enzymatic glycosylation of peptides and oligosaccharides from GalNAc and UTP. ChemBioChem, 2007, 8 (1), pp.37-40. ⟨hal-00282379⟩
  • D. Fenyo, Qj. Wang, Ja. Degrasse, Jc. Padovan, M. Cadene, et al.. MALDI Sample Preparation: the Ultra Thin Layer Method (Videopublication). Journal of visualized experiments : JoVE, 2007, 3, http://www.jove.com/index/details.stp?ID=192. ⟨hal-00282398⟩
  • Nathalie Gillard, Stephane Goffinont, Corinne Buré, Marie Davidkova, Jean-Claude Maurizot, et al.. Radiation-induced oxidative damage to the DNA-binding domain of the lactose repressor. Biochemical Journal, 2007, 403 (3), pp.463-472. ⟨10.1042/BJ20061466⟩. ⟨hal-00478672⟩
  • M. Nishida, Martine Cadene, Bt. Chait, R. Mackinnon. Crystal structure of a Kir3.1-prokaryotic Kir channel chimera. EMBO Journal, 2007, 26, pp.4005-4015. ⟨hal-00282532⟩
  • Vanessa Bourgeaux, Martine Cadène, Friedrich Piller, Véronique Piller. Efficient Enzymatic Glycosylation of Peptides and Oligosaccharides from GalNAc and UTP. ChemBioChem, 2007, 8 (1), pp.37-40. ⟨10.1002/cbic.200600369⟩. ⟨hal-00158348⟩
  • Youxing Jiang, Alice Lee, Jiayun Chen, Vanessa Ruta, Martine Cadène, et al.. X-ray structure of a voltage-dependent K+ channel. Nature, 2003, 423 (6935), pp.33-41. ⟨10.1038/nature01580⟩. ⟨hal-02150132⟩
  • Youxing Jiang, Alice Lee, Jiayun Chen, Martine Cadène, Brian T. Chait, et al.. The open pore conformation of potassium channels. Nature, 2002, 417 (6888), pp.523-526. ⟨10.1038/417523a⟩. ⟨hal-02150141⟩
  • Christoph Seibert, Martine Cadène, Anthony Sanfiz, Brian T. Chait, Thomas Sakmar. Tyrosine sulfation of CCR5 N-terminal peptide by tyrosylprotein sulfotransferases 1 and 2 follows a discrete pattern and temporal sequence. Proceedings of the National Academy of Sciences of the United States of America, 2002, 99 (17), pp.11031-11036. ⟨10.1073/pnas.172380899⟩. ⟨hal-02150135⟩
  • Youxing Jiang, Alice Lee, Jiayun Chen, Martine Cadène, Brian Chait, et al.. X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity. Nature, 2002, 415 (6869), pp.287-294. ⟨10.1038/415287a⟩. ⟨hal-02150146⟩
  • Raimund Dutzler, Ernest Campbell, Martine Cadène, Brian T. Chait, Roderick Mackinnon. X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity. Nature, 2002, 415 (6869), pp.287-294. ⟨10.1038/415287a⟩. ⟨hal-02150160⟩
  • L.J Lambert, V Schirf, B Demeler, Martine Cadene, M Werner. Flipping a genetic switch by subunit exchange. EMBO Journal, 2001, 20 (24), pp.7149-7159. ⟨10.1093/emboj/20.24.7149⟩. ⟨hal-02150170⟩
  • Y Jiang, A Pico, Martine Cadene, B T. Chait, R Mackinnon. Structure of the RCK domain from the E. coli K+ channel and demonstration of its presence in the human BK channel.. Neuron, 2001, 29 (3), pp.593-601. ⟨hal-02150219⟩
  • N.A Linderoth, M.N Simon, N.A Rodionova, Martine Cadene, W.R Laws, et al.. Biophysical analysis of the endoplasmic reticulum-resident chaperone/heat shock protein gp96/GRP94 and its complex with peptide antigen.. Biochemistry, 2001, 40 (5), pp.1483-95. ⟨hal-02150312⟩
  • P Rudd, A.K Downing, Martine Cadene, D.J Harvey, M.R Wormald, et al.. Hybrid and complex glycans are linked to the conserved N-glycosylation site of the third eight-cysteine domain of LTBP-1 in insect cells.. Biochemistry, 2000, 39 (7), pp.1596-1603. ⟨10.1021/bi9918285⟩. ⟨hal-02150367⟩
  • Martine Cadène, Brian T. Chait. A Robust, Detergent-Friendly Method for Mass Spectrometric Analysis of Integral Membrane Proteins. Analytical Chemistry, 2000, 72 (22), pp.5655-5658. ⟨10.1021/ac000811l⟩. ⟨hal-02150358⟩
  • C Boudier, Martine Cadène, Joseph Bieth. Inhibition of Neutrophil Cathepsin G by Oxidized Mucus Proteinase Inhibitor. Effect of Heparin †. Biochemistry, 1999, 38 (26), pp.8451-8457. ⟨10.1021/bi9828526⟩. ⟨hal-02150373⟩
  • Lihong Wei, Yemiliya Berman, Eduardo Castaño, Martine Cadène, Ronald Beavis, et al.. Instability of the Amyloidogenic Cystatin C Variant of Hereditary Cerebral Hemorrhage with Amyloidosis, Icelandic Type. Journal of Biological Chemistry, 1998, 273 (19), pp.11806-11814. ⟨10.1074/jbc.273.19.11806⟩. ⟨hal-02150384⟩
  • Yves Mély, Martine Cadène, Ingebrigt Sylte, Joseph Bieth. Mapping the Suramin-Binding Sites of Human Neutrophil Elastase: Investigation by Fluorescence Resonance Energy Transfer and Molecular Modeling †. Biochemistry, 1997, 36 (50), pp.15624-15631. ⟨10.1021/bi971029r⟩. ⟨hal-02150389⟩
  • Martine Cadène, Jérôme Duranton, Anne North, Mustapha Si-Tahar, Michel Chignard, et al.. Inhibition of Neutrophil Serine Proteinases by Suramin. Journal of Biological Chemistry, 1997, 272 (15), pp.9950-9955. ⟨10.1074/jbc.272.15.9950⟩. ⟨hal-02150400⟩
  • Martine Cadène, Christian Boudier, Guy Daney de Marcillac, Joseph Bieth. Influence of Low Molecular Mass Heparin on the Kinetics of Neutrophil Elastase Inhibition by Mucus Proteinase Inhibitor(*). Journal of Biological Chemistry, 1995, 270 (22), pp.13204-13209. ⟨10.1074/jbc.270.22.13204⟩. ⟨hal-02150493⟩
  • Martine Cadène, Nicole Morel-Desrosiers, Jean-Pierre Morel, Joseph G. Bieth. Thermodynamic Investigation of the Heparin-Mucus Proteinase Inhibitor Binding. Journal of the American Chemical Society, 1995, 117 (30), pp.7882-7886. ⟨10.1021/ja00135a005⟩. ⟨hal-02150439⟩
  • M Faller, Martine Cadene, J Bieth. Demonstration of a two-step reaction mechanism for the inhibition of heparin-bound neutrophil elastase by alpha 1-proteinase inhibitor.. Biochemistry, 1993, 32 (35), pp.9230-5. ⟨hal-02150537⟩

Communication dans un congrès8 documents

  • Edison F Zhamungui, Cedric Orelle, Jean-Michel Jault, Joekeem del Rosario Arizala, Sébastien F. Poget, et al.. Structural biology of membrane proteins and their complexes using Native Liquid MALDI (NALIM) Mass Spectrometry (MS). Analytics 2022, Sep 2022, Nantes, France. ⟨hal-03845786⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. Architecture et dynamique de protéines histone-like de bactérie et d’archées. Journée BioRMN IdF, Sep 2020, Gif-sur-Yvette, France. ⟨hal-03053296⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. Vers une description cinétique et structurale complète du mécanisme d'échange de chaînes de la protéine HU d'Escherichia coli.. XXXIe congrès du GERM (Groupement d'Etudes de Résonance Magnétique), May 2019, Oléron, France. ⟨hal-02361645⟩
  • G. Gabant, A. Boyer, Y. Berteaux, Martine Cadene. SSPaQ: a new method for the quantification of modification at all possible sites of a protein. 33es Journées de la Société Française de Spectrométrie de Masse, Sep 2016, Bordeaux, France. ⟨hal-02902960⟩
  • Caroline Teyssier, Alexandre Morel, Jean-François Trontin, Françoise Corbineau, Anne-Marie Lomenech, et al.. Did cotyledonary somatic embryos of Pinus pinaster Ait. similar to cotyledonary zygotic embryos ?. International Conference of the IUFRO Working Party 2.09.02: Somatic Embryogenesis and Other Vegetative Propagation Technologies, Sep 2014, Vitoria-Gasteiz, Spain. ⟨hal-03809831⟩
  • Alexandre Morel, Caroline Teyssier, Jean-François Trontin, Kateřina Eliášová, Pešek Bedřichc, et al.. Multi-scale analysis of early molecular events during Pinus pinaster Ait. somatic embryo development under reduced water availability. 3. International Conference of the IUFRO Working Party 2.09.02: Somatic Embryogenesis and Other Vegetative Propagation Technologies, International Union of Forest Research Organisations (IUFRO). Vienne, AUT., Sep 2014, Vitoria-Gasteiz, Spain. 220 p. ⟨hal-02740937⟩
  • Chrystelle Derache, Hervé Meudal, Vincent Aucagne, Martine Cadène, Agnès Delmas, et al.. First insights into the structure-activity relationships of avian beta-defensins.. 2nd International Symposium on Antimicrobial Peptides - Food Veterinary Medical and Novel Applications., 2009, Saint-Malo, France. ⟨hal-02753345⟩
  • C Derache, H Meudal, V Aucagne, M Cadène, A Delmas, et al.. 1ère structure 3D d'une défensine antibactérienne de poulet. 21e Colloque Biotechnocentre, 2008, Seillac, France. ⟨hal-02752777⟩

Poster23 documents

  • Lucija Mance, Nicolas Bigot, Edison Zhamungui Sánchez, Franck Coste, Natalia Martín-González, et al.. Studies of BTB domain polymerisation through integrative structural biology. FRISBI User Meeting 2024, CNRS campus Gif-sur-Yvette, Jan 2024, Gif sur Yvette, France. ⟨hal-04778726⟩
  • David Gosset, Julien Sobilo, Herve Meudal, Frederic Szeremeta, Marylène Bertrand, et al.. Plateforme MO2VING: from MOlecular Organization to in Vivo ImagiNG. 34ème Colloque Biotechnocentre, Oct 2022, Nouan Le Fuzelier, France. ⟨hal-03863246⟩
  • Guillaume Gabant, Matej Nemcic, Fanny Ruhland, Timothée Toussaint, Christophe Lucas, et al.. Protein profiling by MS shows evidence of royal protein pheromones in the cuticle extracts of the termite Reticulitermes flavipes. Analytics 2022, Sep 2022, Nantes, France. 2022. ⟨hal-03845797⟩
  • Edison F Zhamungui, Cedric Orelle, Jean-Michel Jault, Joekeem del Rosario Arizala, Sébastien F. Poget, et al.. NALIM: NATIVE LIQUID MALDI MASS SPECTROMETRY AS A NEW STRUCTURAL METHOD TO DIRECTLY CHARACTERIZE MEMBRANE PROTEIN COMPLEXES. IMSC (International Mass Spectrometry Conference), Aug 2022, Maastricht, Netherlands. ⟨hal-03863124⟩
  • Edison F Zhamungui, Martine Beaufour, Martine Cadene. Search for a high-mass calibrant for NALIM (Native Liquid MALDI MS): the case of mouse IgA. Journées Françaises de Spectrométrie de Masse, Jun 2021, Virtual, France. , 2020, ⟨10.7554/elife.56098⟩. ⟨hal-03404684⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system.. Journée Fédération de recherche “Physique et Chimie du Vivant”, Apr 2019, Orléans, France. ⟨hal-02362578⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system. NMR : a tool for biology XITh, Jan 2019, Paris, France. ⟨hal-02362588⟩
  • G. Gabant, M. Nemcic, J. Pinetre, Martine Cadene. Tuning ETD Top Down MS parameters on a UHR-QTOF instrument to improve protein the fragmentation coverage. SMMAP 2019, Sep 2019, Strasbourg, France. ⟨hal-02902968⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Celine Landon, A.F. Delmas, et al.. First kinetics description of the EcHU chain exchange system.. 28th ICMRBS - International Council on Magnetic Resonance in Biological Systems, Aug 2018, Dublin, Ireland. ⟨hal-02362586⟩
  • Justine Largillière, Rémy Le Meur, David Ginguené, Norbert Garnier, Celine Landon, et al.. To a complete kinetics and structural description of the EcHU chain exchange system.. 31e colloque Biotechnocentre, Oct 2018, Seillac, France. ⟨hal-02362818⟩
  • Justine Largillière, Rémy Le Meur, Martine Cadene, Bertrand Castaing, Karine Loth, et al.. Premières études cinétiques du mécanisme d’échange de chaînes de la protéine HU d’Escherischia coli.. Journée Fédération de recherche “Physique et Chimie du Vivant”, Jan 2018, Orléans, France. ⟨hal-02362577⟩
  • Justine Largillière, Rémy Le Meur, Martine Cadene, Bertrand Castaing, Karine Loth, et al.. Premières études cinétiques du mécanisme d’échange de chaînes de la protéine HU d’Escherischia coli.. 16e colloque scientifique de l’ADOC : Converger pour Renforcer, Apr 2018, Orléans, France. ⟨hal-02362579⟩
  • Justine Largillière, Rémy Le Meur, Martine Cadene, Bertrand Castaing, Karine Loth, et al.. Première description cinétique du mécanisme d’échange de chaînes de la protéine HU d'Escherichia coli.. 30e colloque Biotechnocentre, Oct 2017, Seillac, France. ⟨hal-02361632⟩
  • T. Bijot, G. Gabant, Martine Cadene. Development of an original footprinting approach to localize non-covalent ligand binding sites. 30e Colloque Biotechnocentre, Oct 2017, Seillac, France. ⟨hal-02902974⟩
  • T. Bijot, G. Gabant, Martine Cadene. Towards a faster localization of noncovalent ligand binding sites using an original footprinting method. SMMAP 2017, Oct 2017, Marne-la-Vallée, France. ⟨hal-02902978⟩
  • G. Gabant, Martine Cadene. Assessing chemical labeling of proteins by mass spectrometry: MALDI−TOF to the rescue of ESI−HRMS. SMMAP 2017, Oct 2017, Marne-la-Vallée, France. ⟨hal-02902984⟩
  • T. Bijot, G. Gabant, Martine Cadene. Towards a faster localization of noncovalent ligand binding sites using an original footprinting method. 11es Journées du Cancéropôle Grand Ouest, Jun 2017, Vannes, France. ⟨hal-02902989⟩
  • G. Gabant, A. Boyer, Martine Cadene. SSPaQ: a subtractive method for the parallel quantification of the degree of modification at every possible site of a protein. 64th ASMS Conference, Jun 2016, San-Antonio, Texas, United States. ⟨hal-02903009⟩
  • G. Gabant, Y. Richer, S. Motteau, E. Mebold, Martine Cadene. Towards a prediction of protein reactivity against electrophile ligands: 1. Ranking amino acid side chain nucleophilicities. 64th ASMS Conference, Jun 2016, San Antonio, Texas, United States. ⟨hal-02903017⟩
  • Caroline Teyssier, Alexandre Morel, Jean-François Trontin, Francoise Corbineau, Anne-Marie Lomenech, et al.. Are cotyledonary somatic embryos of Pinus pinaster Ait. equivalent to the zygotic counterpart ?. 3. International Conference of the IUFRO Working Party 2.09.02: Somatic Embryogenesis and Other Vegetative Propagation Technologies, Sep 2014, Vitoria-Gasteiz, Spain. 2014, 3rd International Conference of the IUFRO Working Party 2.09.02: Somatic Embryogenesis and Other Vegetative Propagation Technologies. Book of Abstracts. ⟨hal-01269493⟩
  • Alexandre Morel, Caroline Teyssier, Martine Beaufour, Isabelle Reymond, Claire Le Mette, et al.. Somatic embryo maturation in maritime pine (Pinus pinaster) : contribution of a 2-DE proteomic analysis for a better understanding. 2. International Conference of the IUFRO Working Party 2.09.02, "Somatic Embryogenesis and Other Vegetative Propagation Technologies", Jun 2012, Brno, Czech Republic. 2012, Integrating vegetative propagation, biotechnologies and genetic improvement for tree production and sustainable forest management. Proceedings. ⟨hal-01268054⟩
  • Marie-Anne Lelu-Walter, Alexandre A. Morel, Caroline Teyssier, Martine Beaufour, Isabelle Reymond, et al.. Somatic embryo development in maritime pine (Pinus pinaster): a 2-DE proteomic analysis. 4. UPSC-INRA (UPRA) Bilateral Meeting, Mar 2012, Umea, Sweden. 2012, 4th UPSC-INRA (UPRA) bilateral meeting. Meeting book with abstracts. ⟨hal-02746152⟩
  • Martine Beaufour, Alexandre A. Morel, Caroline Teyssier, Luc Harvenght, Jean-François Trontin, et al.. Differential proteomics for the evaluation of the effect of environmental culture conditions on the protein expression of somatic embryos from Pinus pinaster. SMAP 2011 - 28èmes Journées Françaises de Spectrométrie de Masse, Sep 2011, Avignon, France. 2011, Spectroscopie de Masse et Analyse Protéomique. ⟨hal-02746570⟩

Chapitre d'ouvrage1 document

  • Françoise Culard, Mélanie Spotheim-Maurizot, Corinne Bure, Stéphane Goffinont, Martine Cadene. A mass spectrometry approach for the identification of oxidation-sensitive residues in DNA-binding proteins: correlation with protein function. Pandey, A., Banerjee, R. Horizons in Biotechnology, Asiatech Publishers, New Delhi, pp.123-134, 2008. ⟨hal-00623581⟩

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BONMATIN Jean-Marc

email : jean-marc.bonmatin[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.55.87

Senior Researcher, responsible of the thematic group “Pesticides: Environment, Biodiversity and Health”


148 documents

Article dans une revue75 documents

  • Jean-Marc Bonmatin, Camille Pasquet, François Chamaraux, Laurence Huc. SDHI : ces pesticides agricoles qui inquiètent les scientifiques. Abeille de France et l'Apiculteur, 2025, 1130, pp.31-33. ⟨hal-04890980⟩
  • Jean-Marc Bonmatin, Camille Pasquet, François Chamaraux, Laurence Huc. HOLIMITOX : Le réseau de chercheurs indépendants sur les pesticides SDHI.. Abeilles et Fleurs, 2025, 877, pp.46-49. ⟨hal-04915294⟩
  • Kumiko Taira, Yoshinori Ikenaka, Jean-Marc Bonmatin, Anton Safer. Human plasma protein bindings of neonicotinoid insecticides and metabolites. Scientific Reports, 2025, 15, pp.13155. ⟨10.1038/s41598-025-96812-y⟩. ⟨hal-05039239⟩
  • Camille Pasquet, Sylvie Guinchard, Marie Villier, Eléa Guyaz, Jean-Marc Bonmatin, et al.. Development and validation of a highly sensitive method for the analysis of succinate dehydrogenase inhibitors (SDHIs) in plant-based food and beverages. Food Chemistry, 2025, 485, pp.144532. ⟨10.1016/j.foodchem.2025.144532⟩. ⟨hal-05058010⟩
  • Thomas Perrot, Jean-Marc Bonmatin, Hervé Jactel, Christophe Leboulanger, Robin Goffaux, et al.. Temporal and spatial trends of imidacloprid-related hazards in France. Science of the Total Environment, 2024, 945, pp.173950. ⟨10.1016/j.scitotenv.2024.173950⟩. ⟨hal-04611833⟩
  • Kumiko Taira, Alexandre Aebi, Gaétan Glauser, Edward A. D. Mitchell, Yoshinori Ikenaka, et al.. Urinary neonicotinoids in rural population of the Philippines and comparison with paired hair samples. Japanese journal of clinical ecology, 2023, 32 (2), pp.59-76. ⟨hal-04630327⟩
  • Chiara Giorio, Anton Safer, Francisco Sánchez-Bayo, Andrea Tapparo, Andrea Lentola, et al.. An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides. Part 1: new molecules, metabolism, fate, and transport. Environmental Science and Pollution Research, 2021, ⟨10.1007/s11356-017-0394-3⟩. ⟨hal-02068718⟩
  • Jean-Marc Bonmatin, Edward A.D. Mitchell, Gaëtan Glauser, Elizabeth Lumawig-Heitzman, Florencia Claveria, et al.. Residues of neonicotinoids in soil, water and people's hair: A case study from three agricultural regions of the Philippines. Science of the Total Environment, 2021, 757, pp.143822. ⟨10.1016/j.scitotenv.2020.143822⟩. ⟨hal-03086458⟩
  • Jean-Marc Bonmatin. To bee or not to bee, l’exemple édifiant des insecticides néonicotinoïdes. A3 magazine, 2021, 77, pp.21-26. ⟨hal-03470797⟩
  • Noa Simon-Delso, Alexandre Aebi, Gerard Arnold, Jean-Marc Bonmatin, Fani Hatjina, et al.. Maximize EU pollinator protection: Minimize risk. Science, 2021, 373 (6552), pp.290.2-290. ⟨10.1126/science.abj8116⟩. ⟨hal-03325918⟩
  • Lennard Pisa, Dave Goulson, En-Cheng Yang, David Gibbons, Francisco Sánchez-Bayo, et al.. An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides. Part 2: impacts on organisms and ecosystems. Environmental Science and Pollution Research, 2021, ⟨10.1007/s11356-017-0341-3⟩. ⟨hal-02071713⟩
  • K.L. L Mahefarisoa, N. Simon Delso, V. Zaninotto, M. E. Colin, J.M. Bonmatin. The threat of veterinary medicinal products and biocides on pollinators: A One Health perspective. One Health, 2021, 12, ⟨10.1016/j.onehlt.2021.100237⟩. ⟨hal-03186718⟩
  • Jean-Marc Bonmatin, Chiara Giorio, Francisco Sánchez-Bayo, Maarten Bijleveld van Lexmond. An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides. Environmental Science and Pollution Research, 2021, 28 (10), pp.11709-11715. ⟨10.1007/s11356-021-12853-6⟩. ⟨hal-03156279⟩
  • Marion Desquilbet, Pierre-André Cornillon, Laurence Gaume, Jean-Marc Bonmatin. Adequate statistical modelling and data selection are essential when analysing abundance and diversity trends. Nature Ecology & Evolution, 2021, 5 (5), pp.592-594. ⟨10.1038/s41559-021-01427-x⟩. ⟨hal-03191511v3⟩
  • Kris Wyckhuys, Francisco Sanchez-Bayo, Alexandre Aebi, Maarten Bijleveld van Lexmond, Jean-Marc Bonmatin, et al.. Stay true to integrated pest management. Science, 2021, 371 (6525), pp.133.1-133. ⟨10.1126/science.abf8072⟩. ⟨hal-03106280⟩
  • Kumiko Taira, Tomonori Kawakami, Sujithra Kaushaliya Weragoda, H. Herath, Yoshinori Ikenaka, et al.. Urinary concentrations of neonicotinoid insecticides were related to renal tubular dysfunction and neuropsychological complaints in Dry-zone of Sri Lanka. Scientific Reports, 2021, 11 (1), pp.22484. ⟨10.1038/s41598-021-01732-2⟩. ⟨hal-03573005⟩
  • Kris A.G. Wyckhuys, Alexandre Aebi, Maarten F.I.J. Bijleveld van Lexmond, Carlos Bojaca, Jean-Marc Bonmatin, et al.. Resolving the twin human and environmental health hazards of a plant-based diet. Environment International, 2020, 144, pp.106081. ⟨10.1016/j.envint.2020.106081⟩. ⟨hal-02930817⟩
  • Jean-Marc Bonmatin, Martine Regert. Abeilles, une histoire intime avec l'humanité. Abeilles et Fleurs, 2020, 824, pp.24-27. ⟨hal-05046788⟩
  • Marion Desquilbet, Laurence Gaume, Manuela Grippa, Régis Céréghino, Jean-François Humbert, et al.. Comment on “Meta-analysis reveals declines in terrestrial but increases in freshwater insect abundances”. Science, 2020, 370 (6523), ⟨10.1126/science.abd8947⟩. ⟨hal-03082926⟩
  • Andrea Veres, Kris A. G. Wyckhuys, József Kiss, Ferenc Toth, Giovanni Burgio, et al.. An update of the Worldwide Integrated Assessment (WIA) on systemic pesticides. Part 4: Alternatives in major cropping systems. Environmental Science and Pollution Research, 2020, 27 (24), pp.29867-29899. ⟨10.1007/s11356-020-09279-x⟩. ⟨hal-02916388⟩
  • D. Mitchell E. A., A. Aebi, F. Sanchez-Bayo, D. Goulson, N. Simon Delso, et al.. Engineered symbionts to safeguard honeybee health and their pollination services: A response. eLetters, Science, 2020, ⟨10.1126/science.aax9039⟩. ⟨hal-02498542⟩
  • Martine Regert, Jean-Marc Bonmatin. Le rendez-vous du mois. Abeilles, une histoire intime avec l'humanité. Abeilles et Fleurs, 2020, 824, pp.24-27. ⟨hal-02501063⟩
  • Go Ichikawa, Ryota Kuribayashi, Yoshinori Ikenaka, Takahiro Ichise, Shouta Nakayama, et al.. LC-ESI/MS/MS analysis of neonicotinoids in urine of very low birth weight infants at birth. PLoS ONE, 2019, 14 (7), pp.e0219208. ⟨10.1371/journal.pone.0219208⟩. ⟨hal-02321502⟩
  • Jean-Marc Bonmatin, Dominique Noome, Heron Moreno, Edward A.D. Mitchell, Gaétan Glauser, et al.. A survey and risk assessment of neonicotinoids in water, soil and sediments of Belize. Environmental Pollution, 2019, 249, pp.949-958. ⟨10.1016/j.envpol.2019.03.099⟩. ⟨hal-02107559⟩
  • Dave Goulson, Jennifer Sills, Hans Frey,, Sarah Tzinieris,, Edouard Colin, Marc, et al.. Call to restrict neonicotinoids. Science, 2018, 360 (6392), pp.973.1-973. ⟨10.1126/science.aau0432⟩. ⟨hal-02107652⟩
  • Dave Goulson, Jean-Marc Bonmatin. Call to restrict neonicotinoids. Science, 2018, 360 (6392), pp.973-973. ⟨10.1126/science.aau0432⟩. ⟨hal-03675124⟩
  • Lorenzo Furlan, Alberto Pozzebon, Carlo Duso, Noa Simon-Delso, Francisco Sánchez-Bayo, et al.. An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides. Part 3: alternatives to systemic insecticides. Environmental Science and Pollution Research, 2018, ⟨10.1007/s11356-017-1052-5⟩. ⟨hal-02501013⟩
  • Emilie Egea, Wilfried Sanchez, Philippe Garrigues, Gela Alemayehu Bayeta, Andres Arce, et al.. The Rovaltain Foundation Engages in Pollinator Health. Bee World, 2018, 95 (1), pp.20-21. ⟨10.1080/0005772X.2017.1408932⟩. ⟨hal-02082351⟩
  • Francisco Sánchez-Bayo, Luc Belzunces, Jean-Marc Bonmatin. Lethal and sublethal effects, and incomplete clearance of ingested imidacloprid in honey bees (Apis mellifera). Ecotoxicology, 2017, 26 (9), ⟨10.1007/s10646-017-1845-9⟩. ⟨hal-01606746⟩
  • Peter Paul Hoppe, Anton Safer, Vanessa Amaral-Rogers, Jean-Marc Bonmatin, Dave Goulson, et al.. Effects of a neonicotinoid pesticide on honey bee colonies: a response to the field study by Pilling et al. (2013). Environmental Science Europe, 2015, 27 (1), ⟨10.1186/s12302-015-0060-7⟩. ⟨hal-02072264⟩
  • L.W. Pisa, V. Amaral-Rogers, Luc Belzunces, J-M. Bonmatin, C.A. Downs, et al.. Effects of neonicotinoids and fipronil on non-target invertebrates. Environmental Science and Pollution Research, 2015, 22 (1), pp.68-102. ⟨10.1007/s11356-014-3471-x⟩. ⟨hal-02641065⟩
  • J. P. van Der Sluijs, V. Amaral-Rogers, L.P. Belzunces, M. F. I. J. Bijleveld van Lexmond, J-M. Bonmatin, et al.. Conclusions of the Worldwide Integrated Assessment on the risks of neonicotinoids and fipronil to biodiversity and ecosystem functioning. Environmental Science and Pollution Research, 2015, 22 (1), pp.148-154. ⟨10.1007/s11356-014-3229-5⟩. ⟨hal-01171970⟩
  • J.-M. Bonmatin, C. Giorio, V. Girolami, D. Goulson, D. P. Kreutzweiser, et al.. Expositions et devenirs environnementaux ; néonicotinoïdes et fipronil. Environmental Science and Pollution Research, 2015, pp.35-67. ⟨10.1007/s11356-014-3332-7⟩. ⟨hal-01170672⟩
  • Robert Paxton, Mark Brown, Michael Kuhlmann, Dave Goulson, Axel Decourtye, et al.. Entomology: The bee-all and end-all. Nature, 2015, 521 (7552), pp.S57-S59. ⟨10.1038/521S57a⟩. ⟨hal-02082386⟩
  • N Simon-Delso, V. Amaral-Rogers, Luc Belzunces, J-M. Bonmatin, M. Chagnon, et al.. Systemic insecticides (neonicotinoids and fipronil): trends, uses, mode of action and metabolites. Environmental Science and Pollution Research, 2015, 22 (1), pp.5-34. ⟨10.1007/s11356-014-3470-y⟩. ⟨hal-02641649⟩
  • Delphine Paradis, Géraldine Bérail, Jean-Marc Bonmatin, Luc Belzunces. Sensitive analytical methods for 22 relevant insecticides of 3 chemical families in honey by GC-MS/MS and LC-MS/MS. Analytical and Bioanalytical Chemistry, 2014, 406 (2), pp.621-633. ⟨10.1007/s00216-013-7483-z⟩. ⟨hal-02635189⟩
  • Gaël Charpentier, Fanny Louat, Jean-Marc Bonmatin, Patrice A. Marchand, Fanny Vanier, et al.. Lethal and sublethal effects of imidacloprid, after chronic exposure, on the insect model Drosophila melanogaster. Environmental Science and Technology, 2014, 48 (7), pp.4096-4102. ⟨10.1021/es405331c⟩. ⟨hal-01178479⟩
  • Jeroen P van Der Sluijs, Noa Simon-Delso, Dave Goulson, Laura Maxim, Jean-Marc Bonmatin, et al.. Neonicotinoids, bee disorders and the sustainability of pollinator services. Current Opinion in Environmental Sustainability, 2013, 5 (3-4), pp.293-305. ⟨10.1016/j.cosust.2013.05.007⟩. ⟨hal-00874897⟩
  • Marc-Edouard Colin, Patrice Marchand, Jean-Marc Bonmatin. L'apiculture écologique. L'Ecologiste, 2007, 21, pp.41-43. ⟨hal-00170381⟩
  • Qiasong Zhang, Juliette R. Ongus, Willem Jan Boot, Johan Calis, Jean-Marc Bonmatin, et al.. Detection and localisation of picorna-like virus particles in tissues of Varroa destructor, an ectoparasite of the honey bee, Apis mellifera. Journal of Invertebrate Pathology, 2007, 96 (2), pp.97-105. ⟨10.1016/j.jip.2007.03.019⟩. ⟨hal-00159630⟩
  • J.M. Bonmatin, P.A. Marchand, R. Charvet, I. Moineau, E.R. Bengsch, et al.. Quantification of imidacloprid uptake in maize crops. Journal of Agricultural and Food Chemistry, 2005, 53, pp.5336-5341. ⟨hal-00088508⟩
  • R. Charvet, M. Katouzian-Safadi, Colin M.E., Marchand P.A., Bonmatin J.M.. Systemic insecticides: new risks for pollinator insects. Annales Pharmaceutiques Françaises, 2004, 62 (1), pp.29-35. ⟨10.1016/S0003-4509(04)94278-2⟩. ⟨hal-00112964⟩
  • Mélanie Colin, J.M. Bonmatin, I. Moineau, C. Gaimon, J.P. Vermandère. A method to quantify and analyze the foraging activity of honey bees: relevance to the sublethal effects induced by systemic insecticides. Archives of Environmental Contamination and Toxicology, 2004, 47, pp.387-395. ⟨hal-02681546⟩
  • M.E. Colin, J.M. Bonmatin, I. Moineau, C. Gaimon, S. Brun, et al.. A method to quantify and analyze the foraging activity of honey bees: relevance to the sublethal effects induced by systemic insecticides. Archives of Environmental Contamination and Toxicology, 2004, 47 (3), pp.387-395. ⟨10.1007/s00244-004-3052-y⟩. ⟨hal-00112970⟩
  • Juliette Ongus, Dick Peters, Jean-Marc Bonmatin, Eberhard Bengsch, Just Vlak, et al.. Complete sequence of a picorna-like virus of the genus Iflavirus replicating in the mite varroa destructor. Journal of General Virology, 2004, 85, pp.3747-3755. ⟨10.1099/vir.0.80470-0⟩. ⟨hal-00113080⟩
  • Roland Charvet, Mehrnaz Katouzian-Safadi, Marc-Edouard Colin, Patrice A Marchand, Jean-Marc Bonmatin. Insecticides systémiques : de nouveaux risques pour les insectes pollinisateurs. Annales Pharmaceutiques Françaises, 2004, 62 (1), pp.29-35. ⟨10.1016/S0003-4509(04)94278-2⟩. ⟨hal-02082454⟩
  • Jean-Marc Bonmatin, Olivier Laprévote, Françoise Peypoux. Diversity among microbial cyclic lipopeptides: iturins and surfactins. Activity-structure relationships to design new bioactive agents.. Combinatorial Chemistry and High Throughput Screening, 2003, 6 (6), pp.541-56. ⟨hal-02082474⟩
  • Mehrnaz Katouzian-Safadi, Jean-Marc Bonmatin. The use of honey in the simple and composed drugs at Rhazés. Revue d'histoire de la pharmacie, A paraître, 51 (337), pp.29-36. ⟨hal-02082483⟩
  • J.M. Bonmatin, I. Moineau, R. Charvet, Mélanie Colin, E.R. Bengsch. A LC/APCI-MS/MS method for analysis of imidacloprid in soils, in plants and in pollens. Analytical Chemistry, 2003, 75, pp.2027-2033. ⟨hal-02677949⟩
  • J.M. Bonmatin, I. Moineau, R. Charvet, C. Fléché, M.E. Colin, et al.. A LC/APCI-MS/MS method for analysis of imidacloprid in soils, in plants and in pollens. Analytical Chemistry, 2003, 75 (9), pp.2027-2033. ⟨10.1021/ac020600b⟩. ⟨hal-00087695⟩
  • Joëlle Ricordel, Jean-Marc Bonmatin. Honey's virtues in theriacs. Revue d'histoire de la pharmacie, 2003, 51 (337), pp.21-8. ⟨hal-02082486⟩
  • Mélanie Colin, Marc Tchamitchian, J.M. Bonmatin, Sébastien Di Pasquale. Presence of chitinase in adult Varroa destructor, an ectoparasite mite of Apis mellifera. Experimental and Applied Acarology, 2002, 25, pp.947-955. ⟨hal-02678200⟩
  • Marc Colin, Marc Tchamitchian, Jean-Marc Bonmatin, Sylvie Di Pasquale. Presence of chitinase in adult Varroa destructor, an ectoparasitic mite of Apis mellifera. Experimental and Applied Acarology, 2001, 25 (12), pp.947-955. ⟨10.1023/A:1020657906024⟩. ⟨hal-02082513⟩
  • J.M. Bonmatin, I. Moineau, Mélanie Colin, E.R. Bengsch. L'insecticide imidaclopride: biodisponibilité dans les sols et les plantes, toxicité et risque pour les abeilles. Abeilles et Fleurs, 2000, 609, pp.360-361. ⟨hal-02698732⟩
  • Nicolas Mandard, Denise Sy, Corinne Maufrais, Jean-Marc Bonmatin, Philippe Bulet, et al.. Androctonin, a Novel Antimicrobial Peptide from Scorpion Androctonus Australis : Solution Structure and Molecular Dynamics Simulations in the Presence of a Lipid Monolayer. Journal of Biomolecular Structure and Dynamics, 1999, 17 (2), pp.367-380. ⟨10.1080/07391102.1999.10508368⟩. ⟨hal-02082519⟩
  • F Peypoux, J Bonmatin, J. Wallach. Recent trends in the biochemistry of surfactin.. Applied Microbiology and Biotechnology, 1999, 51 (5), pp.553-63. ⟨hal-02082527⟩
  • F Grangemard, J.M. Bonmatin, B. Bernillon, B Das, F Peypoux. Lichenysins G, a novel family of lipopeptide biosurfactants from Bacillus licheniformis IM 1307: production, isolation and structural evaluation by NMR and mass spectrometry.. Journal of Antibiotics, 1999, 52 (4), pp.363-73. ⟨hal-02082523⟩
  • F Mandard, P. Sodano, H Labbe, J.M. Bonmatin, P. Bulet, et al.. Solution structure of thanatin, a potent bactericidal and fungicidal insect peptide, determined from proton two-dimensional nuclear magnetic resonance data.. European Journal of Biochemistry, 1998, 256 (2), pp.404-10. ⟨hal-02082530⟩
  • Céline Landon, Patrick Sodano, C. Cornet, J.M. Bonmatin, Charles Kopeyan, et al.. Refined solution structure of the anti-mammal and anti-insect LqqIII scorpion toxin: Comparison with other scorpion toxins. Proteins: Structure, Function, and Genetics, 1997, 28 (3), pp.360-374. ⟨10.1002/(SICI)1097-0134(199707)28:3<360::AID-PROT6>3.0.CO;2-G⟩. ⟨hal-02082536⟩
  • A Grangemard, F Peypoux, J. Wallach, B Das, H Labbé, et al.. Lipopeptides with improved properties: structure by NMR, purification by HPLC and structure-activity relationships of new isoleucyl-rich surfactins.. Journal of Peptide Science, 1997, 3 (2), pp.145-54. ⟨10.1002/(SICI)1099-1387(199703)3:2%3C145::AID-PSC96%3E3.0.CO;2-Y⟩. ⟨hal-02082565⟩
  • C. Landon, C. Cornet, J.M. Bonmatin, C Kopeyan, H. Rochat, et al.. 1H-NMR-derived secondary structure and the overall fold of the potent anti-mammal and anti-insect toxin III from the scorpion Leiurus quinquestriatus quinquestriatus.. European Journal of Biochemistry, 1996, 236 (2), pp.395-404. ⟨hal-02082569⟩
  • M Maget-Dana, J.M Bonmatin, C Hetru, M. Ptak, J Maurizot. The secondary structure of the insect defensin A depends on its environment. A circular dichroism study. Biochimie, 1995, 77 (4), pp.240-4. ⟨10.1016/0300-9084(96)88130-2⟩. ⟨hal-02082593⟩
  • J Faucon, J.M Bonmatin, J Dufourcq, E Dufourc. Acyl chain length dependence in the stability of melittin-phosphatidylcholine complexes. A light scattering and 31P-NMR study. BBA - Biochimica et Biophysica Acta, 1995, 1234 (2), pp.235-243. ⟨10.1016/0005-2736(94)00298-4⟩. ⟨hal-02082588⟩
  • Jean-Marc Bonmatin, Henri Labbé, Isabelle Grangemard, Françoise Peypoux, Régine Maget-Dana, et al.. Production, isolation and characterization of [Leu4]- and [Ile4]surfactins from Bacillus subtilis. Letters in Peptide Science, 1995, 2 (1), pp.41-47. ⟨10.1007/BF00122922⟩. ⟨hal-02082582⟩
  • F. Cornet, J.M. Bonmatin, C Hetru, J. Hoffmann, M. Ptak, et al.. Refined three-dimensional solution structure of insect defensin A.. Structure, 1995, 3 (5), pp.435-48. ⟨hal-02082576⟩
  • Jean-Marc Bonmatin, Monique Genest, Henri Labbé, Marius Ptak. Solution three-dimensional structure of surfactin: A cyclic lipopeptide studied by 1 H-nmr, distance geometry, and molecular dynamics. Biopolymers, 1994, 34 (7), pp.975-986. ⟨10.1002/bip.360340716⟩. ⟨hal-02082601⟩
  • M Peypoux, J.M Bonmatin, H Labbe, G Grangemard, B Das, et al.. [Ala4]surfactin, a novel isoform from Bacillus subtilis studied by mass and NMR spectroscopies.. European Journal of Biochemistry, 1994, 224 (1), pp.89-96. ⟨hal-02082597⟩
  • J. Dufourcq, E. Dufourc, J.C Maillet, I Cornut, E. Thiaudiere, et al.. Peptide-Induced Changes in Structure, Dynamic and Barrier Properties of Liposomes and Membranes. Phosphorus, Sulfur, and Silicon and the Related Elements, 1993, 77 (1-4), pp.113-116. ⟨10.1080/10426509308045632⟩. ⟨hal-02082605⟩
  • J. M. Bonmatin, Monique Genest, Marie-Christine Petit, Édith Gincel, Jean-Pierre Simorre, et al.. Progress in multidimensional NMR investigations of peptide and protein 3-D structures in solution. From structure to functional aspects. Biochimie, 1992, 74 (9-10), pp.825-36. ⟨10.1016/0300-9084(92)90065-M⟩. ⟨hal-00433186⟩
  • Jean-Marc Bonmatin, Jean-Luc Bonnat, Xavier Gallet, Françoise Vovelle, Marius Ptak, et al.. Two-dimensional 1H NMR study of recombinant insect defensin A in water: resonance assignments, secondary structure and global folding. Journal of Biomolecular NMR, 1992, 2 (3), pp.235-256. ⟨10.1007/BF01875319⟩. ⟨hal-02082611⟩
  • M Peypoux, J.M Bonmatin, H Labbé, B Das, M. Ptak, et al.. Isolation and characterization of a new variant of surfactin, the [Val7]surfactin.. European Journal of Biochemistry, 1991, 202 (1), pp.101-6. ⟨hal-02082613⟩
  • Pascale Malon, Jean-Marc Bonmatin, André Brack. Synthesis and characterization of cyclic peptides with hydrolytic activity. Tetrahedron Letters, 1991, 32 (39), pp.5337-5340. ⟨10.1016/S0040-4039(00)92379-7⟩. ⟨hal-02082617⟩
  • Jean Marc Bonmatin, Ian F.C. Smith, Harold Jarrell, David Siminovitch. Use of a comprehensive approach to molecular dynamics in ordered lipid systems: cholesterol reorientation in oriented lipid bilayers. A deuterium NMR relaxation case study. Journal of the American Chemical Society, 1990, 112 (5), pp.1697-1704. ⟨10.1021/ja00161a007⟩. ⟨hal-02082619⟩
  • Erick J. Dufourc, Jean-Marc Bonmatin, Jean Dufourcq. Membrane structure and dynamics by 2H- and 31P-NMR. Effects of amphipatic peptidic toxins on phospholipid and biological membranes. Biochimie, 1989, 71 (1), pp.117-23. ⟨10.1016/0300-9084(89)90141-7⟩. ⟨hal-02082623⟩
  • Jean-Marc Bonmatin, Ian F.C. Smith, Harold Jarrell, David Siminovitch. Orientation dependence of 2H NMR spin-lattice relaxation rates for cholesterol in macroscopically oriented multibilayers. Journal of the American Chemical Society, 1988, 110 (26), pp.8693-8695. ⟨10.1021/ja00234a019⟩. ⟨hal-02082626⟩

Communication dans un congrès53 documents

  • Amélie Crépet, Philippe Quénel, Madeline Carsique, Jeanne Garric, Pascal Sanders, et al.. Integration of the exposome in health risk assessment: the example of chemical mixtures. ISEE 2024: 36th Annual Conference of the International Society of Environmental Epidemiology, Aug 2024, Santiago, Chile. ⟨10.1289/isee.2024.1887⟩. ⟨hal-04689271⟩
  • Jean-Marc Bonmatin, Luc Belzunces, Cyril Vidau, Elodie Nguyen, Amélie Bajolet. TOXIBEES : un logiciel libre pour réduire les impacts des pesticides sur les abeilles. 52ème Congrès du Groupe Français de recherches sur les Pesticides, GFP, Group eFrançais de recherches sur les Pesticides, May 2024, Lyon, France. ⟨hal-04682700⟩
  • Thomas Perrot, Jean-Marc Bonmatin, Hervé Jactel, Christophe Leboulanger, Robin Goffaux, et al.. Tendance temporelle et spatiale des risques pour la biodiversité liée à l'utilisation de l'imidaclopride en France. 52ème Congrès du Groupe Français de recherches sur les Pesticides, Groupe Français de recherches sur les Pesticides, May 2024, Lyon, France. ⟨hal-05039210⟩
  • Jean-Marc Bonmatin. The worldwide integrated assessment on systemic pesticides: the emblematic case of neonicotinoïds. BeeCaution / TFSP post-neonic symposium, Jun 2022, Bergen, Norway. ⟨hal-03870695⟩
  • Jean-Marc Bonmatin. Abeilles et pesticides néonicotinoïdes : Des pollinisateurs aux Humains. Journées Santé-Environnement, Dec 2021, Nice, France. ⟨hal-03870688⟩
  • Jean-Marc Bonmatin. Pesticides agricoles, abeilles, biodiversité et santé. Pourquoi et comment faire autrement ?. Assemblée du GDSA76, Feb 2020, Dieppe, France. ⟨hal-02900105⟩
  • Jean-Marc Bonmatin. Pesticides et abeilles. Table ronde : 3e Université des Abeilles à l’UNESCO, May 2019, Paris, France. ⟨hal-02900089⟩
  • Jean-Marc Bonmatin. Séminaire invité : Pesticides, Environnement et Santé : Les néonicotinoïdes : quelles conséquences ?. Diplôme Inter Universitaire (DIU) de Médecine Environnementale, Jun 2019, Montpellier, France. ⟨hal-02978671⟩
  • Jean-Marc Bonmatin. Pourquoi et comment sortir des pesticides ?. ., Feb 2019, Châteauneuf sur Loire, France. ⟨hal-02901126⟩
  • Jean-Marc Bonmatin. The use of pesticides should be critically considered: the emblematic case of neonicotinoids. SETAC Europe, 29th Annual Meeting, SETAC Europe, May 2019, Helsinki, Finland. ⟨hal-02342193⟩
  • Jean-Marc Bonmatin. Mise à jour de l’évaluation mondiale intégrée sur les insecticides systémiques néonicotinoïdes. Un cas d’école emblématique. 43e Congrès Sanitaire de la FNOSAD "L'abeille : sa santé, ses relations avec la biodiversité", GDSA de Saône-et-Loire, Oct 2019, Mâcon, France. ⟨hal-02407854⟩
  • Jean-Marc Bonmatin. Pesticides et pollinisateurs. Colloque Apinord, Dec 2019, Dunkerque, France. ⟨hal-02900110⟩
  • Jean-Marc Bonmatin. Pesticides, pollinisateurs et biodiversité : le cas emblématique des néonicotinoïdes. Journées de chimie X-ENS-ESPCI 2019, ESPCI, May 2019, Paris, France. ⟨hal-02342200⟩
  • Jean-Marc Bonmatin. Pesticides, environnement et santé : l'exemple édifiant des insecticides néonicotinoïdes. Rendez-vous Santé d’Orléans, May 2019, Orléans, France. ⟨hal-02901109⟩
  • Jean-Marc Bonmatin. Séminaire invité : Zéro pesticides : une autre voie est possible et réaliste : exemple d'un fonds d'assurance mutuel. Rencontre Pesticides et biodiversité : impacts et solutions. Quels effets sur les écosystèmes ?. Le déclin des pollinisateurs, Ministère de la transition Ecologique et Solidaire, Mar 2019, Paris, France. ⟨hal-02978680⟩
  • Jean-Marc Bonmatin. Scientifiques, Apiculteurs, Agriculteurs, décideurs, quel dialogue ?. Colloque du CNRS-MITI Sociétés d’abeilles, sociétés humaines, Jan 2019, Paris, France. ⟨hal-02345830⟩
  • Jean-Marc Bonmatin. Pesticides, pollinisateurs et biodiversité : le cas emblématique des néonicotinoïdes. Colloque du CNRS-MITI Sociétés d’abeilles, sociétés humaines, Jan 2019, Paris, France. ⟨hal-02345793⟩
  • Jean-Marc Bonmatin. Pesticides, abeilles et biodiversité: Pourquoi et comment faire autrement ?. GABI, Feb 2019, Nancy, France. ⟨hal-02901123⟩
  • Jean-Marc Bonmatin. Sortir des pesticides. ., Apr 2019, Saint Martin d'Abbat, France. ⟨hal-02901115⟩
  • Jean-Marc Bonmatin. The updated Worldwide Integrated Assessment on Systemic Pesticides. 2018 International Symposium of TFSP on Impact of and Alternatives to Systematic Pesticides, Jun 2018, Taipei, Taiwan. ⟨hal-02351899⟩
  • Jean-Marc Bonmatin. Mise à jour de l’évaluation mondiale intégrée sur les insecticides systémiques : néonicotinoïdes et fipronil. 1er congrès International d’Apiculture et d’Apithérapie, Syndicat National d'Apiculture, Oct 2018, Rouen, France. https://www.labeilledefrance.com/resume-des-conferences-du-samedi-27-octobre-2018/. ⟨hal-02346008⟩
  • Jean-Marc Bonmatin. Mise à jour de l’évaluation mondiale intégrée sur les insecticides systémiques : néonicotinoïdes et fipronil. Colloque Pollinisateurs, Biodiversité, quelles approches ?, Laboratoire de Biologie des Ligneux et des Grandes Cultures (Université d'Orléans EA 1207 - INRA USC 1328) - IRSTEA (Écosystèmes forestiers EFNO, Nogent-sur-Vernisson) - IRBI (UMR 7261 CNRS, Université de Tours), Apr 2018, Orléans, France. ⟨hal-02351999⟩
  • K Taira, T Kawakami, Sk Weragoda, S Herath, Y Ikenaka, et al.. Biomarkers of Human Exposure to Neonicotinoid Insecticides - Two Recent International Cooperative Studies. 2018 International Scientific Symposium, Task Force on Systemic Pesticides (TFSP) and University of Southeastern Philippines (Usep), Jul 2018, Tsu, Japan. ⟨hal-02351962⟩
  • Jean-Marc Bonmatin. L’évaluation intégrée sur les pesticides systémiques. Symposium Biodiversité et néonicotinoïdes, Assemblée Nationale, Sep 2018, Paris, France. ⟨hal-02900057⟩
  • Jean-Marc Bonmatin. Impacts des insecticides agricoles sur les abeilles, les pollinisateurs et la biodiversité. Colloque de la SAR, Mar 2018, Lullier, Suisse. ⟨hal-02352026⟩
  • Jean-Marc Bonmatin. Update of the worldwide integrated assessment on systemic pesticides. Congress SCF18, Société Chimique de France, Jul 2018, Montpellier, France. ⟨hal-02351110⟩
  • Jean-Marc Bonmatin. Quelle attitude face à une « fausse vérité » ? Un chercheur face aux intérêts économiques. Colloque interdisciplinaire Sciences et Médias, BNF, May 2018, Paris, France. ⟨hal-02900061⟩
  • Jean-Marc Bonmatin. Pesticides. Rencontres Sciences et Citoyens, Les rencontres du CNRS, Mar 2018, Caen, France. ⟨hal-02901129⟩
  • Jean-Marc Bonmatin. The updated Worldwide Integrated Assessment on Systemic Pesticides. International scientific symposium on the impact of, and alternative to systemic pesticides, Jun 2018, Davao, Philippines. ⟨hal-02351922⟩
  • Jean-Marc Bonmatin. Séminaire invité : Sécurité environnementale : le cas des insecticides néonicotinoïdes. IUT-HSE, Oct 2018, La Ciotat, France. ⟨hal-02978687⟩
  • Jean-Marc Bonmatin. The scientific findings of the IUCN/TFSP literature reviews of the effects of systemic pesticides. Neonicotinoids and their Impact on Ecosystem Services for Agriculture and Biodiversity in Africa, IAP Science Health Policy, Nov 2018, Pretoria, South Africa. http://www.interacademies.org/48926/Assessing-the-Impact-of-Neonicotinoids-in-Africa. ⟨hal-02345907⟩
  • Jean-Marc Bonmatin. L’apiculture est-elle encore possible sans un changement de l’agriculture ?. Congrès International d’apiculture et d’apithérapie de Rouen 2018, Syndicat National d’Apiculture en partenariat avec le Syndicat Apicole de Haute Normandie et l’Association Francophone d’Apithérapie, Oct 2018, Rouen, France. ⟨hal-02350968⟩
  • Jean-Marc Bonmatin. Impacts des insecticides agricoles sur les abeilles, les pollinisateurs et la biodiversité. 1e Journée régionale apicole, GDSA85 (Groupement de défense sanitaire des abeilles de Vendée), Feb 2018, Poiroux, France. ⟨hal-02353997⟩
  • Jean-Marc Bonmatin. Integrated Pest Management and protection of growers by a mutual insurance against pitfalls: one alternative to systemic pesticide use. Belize Forum on Systemic Pesticides, Jun 2017, Belmopan, Belize. ⟨hal-02354464⟩
  • Jean-Marc Bonmatin. Agricultural use of systemic insecticides and their impacts on pollination, invited conference. International science symposium on the impact of and alternatives to systemic pesticides on biodiversity and ecosystems, Mar 2017, Nay Pyi Taw, Myanmar (Burma). ⟨hal-02354506⟩
  • Jean-Marc Bonmatin. Neonicotinoids and public health. 10th Workshop on systemic pesticides, Nov 2017, Padoue, Italy. ⟨hal-02354194⟩
  • Jean-Marc Bonmatin. Neonicotinoids: effects on biodiversity and ecosystems: the issue of highly toxic pesticides in the world. Neonicotinoids: Is a Total Ban in Sight?, NGO POLLINIS, Nov 2017, Bruxelles, Belgique. pp.22-25. ⟨hal-02406832⟩
  • Jean-Marc Bonmatin. Agricultural use of systemic insecticides and their impacts on pollination. Agricultural use of systemic insecticides and their International Symposium on The Impact Of Systemic Pesticides on Ecosystems and Strategies For Pesticide Reduction And Improving Food Safety, Zhejiang Academy of Agricultural Sciences; International Union for Conservation of Nature (IUCN), Mar 2017, Hangzhou, China. ⟨hal-02354523⟩
  • Jean-Marc Bonmatin. Séminaire invité : Global research uncovers new, threatening ecological impacts from neonicotinoid pesticides. Symposium Systemic pesticides, Sep 2017, Ottawa, Canada. ⟨hal-02978689⟩
  • Jean-Marc Bonmatin. Update of the Worldwide Integrated Assessment of the effects of systemic pesticides on biodiversity and ecosystems. Impacts of and alternatives to systemic pesticides, David Suzuki Foundation and York University, Sep 2017, York, United States. ⟨hal-02407467⟩
  • Jean-Marc Bonmatin. Séminaire invité : Update of the Worldwide Integrated Assessment of the effects of systemic pesticides on biodiversity and ecosystems. Symposium of the French Embassy, Sep 2017, Ottawa, Canada. ⟨hal-02978693⟩
  • Jean-Marc Bonmatin. Mise à jour de l’évaluation mondiale intégrée sur les insecticides systémiques néonicotinoïdes ; un cas d’école emblématique. 43e Congrès Sanitaire de la FNOSAD, Oct 2017, Mâcon, France. ⟨hal-02900054⟩
  • Jean-Marc Bonmatin. Séminaire invité : Identification des usages des néonicotinoïdes et des alternatives chimiques ou agronomiques. ANSES Groupe de Travail Alternatives aux néonicotinoïdes, May 2016, Helsinki, Finlande. ⟨hal-02978697⟩
  • Jean-Marc Bonmatin. Neonicotinoids: fate, behavior, and effects on biodiversity and ecosystems (and more generally, the issue of pesticides on our planet). Forum ECO-TOX, Fondation Rovaltain, Fondation Rovaltain, Oct 2016, Alixan, France. ⟨hal-02407428⟩
  • Jean-Marc Bonmatin. Neonicotinoids. 9th Working Meeting on systemic pesticides, Nov 2016, Padoue, Italy. ⟨hal-02899662⟩
  • Jean-Marc Bonmatin. Insecticides néonicotinoides : Evaluation mondiale intégrée des impacts sur la biodiversité. 46e congrès du Groupe Français des Pesticides (GFP), May 2016, Bordeaux, France. ⟨hal-02900098⟩
  • Jean-Marc Bonmatin. Worldwide Integrated Assessment on systemic pesticides: Neonicotinoids, pollinators, biodiversity and food. Symposium on systemic pesticides, faculty of science and engineering, Waseda University, Jun 2016, Tokyo, Japan. ⟨hal-02900047⟩
  • Jean-Marc Bonmatin. Table ronde : Pesticides et impacts sur l’abeille. 21e Congrès National de l’Apiculture Française, Oct 2016, Clermont-Ferrand, France. ⟨hal-02900074⟩
  • Jean-Marc Bonmatin. Biodiversity and food production are threatened by neonicotinoids: The Worldwide Integrated Assessment on systemic pesticides. Symposium on impacts of and alternatives to systemic pesticides, Jun 2016, Manille, Philippines. ⟨hal-02900052⟩
  • Jean-Marc Bonmatin, P.A. Marchand, Gaëlle Danièle, Hervé Casabianca, Marc-Edouard Colin, et al.. Impact of environmental toxins: bioavailability of systemic insecticides il pollen and interactions with bee colonies. International Conference on Pollinator Biology, Health and Policy, Jul 2010, State College, Pennsylvania, United States. ⟨hal-00639757⟩
  • J.M. Bonmatin, P.A. Marchand, S. Sobanska, M.E. Colin, L.P. Belzunces. Colony Collapse Disorder (CCD): Detection of systemic insecticides and interactions with pollinators. 7th international conference "Aegean Analytical Chemistry Days", Sep 2010, Lesvos, Greece. ⟨hal-00831542⟩
  • Gaëlle Danièle, Hervé Casabianca, Marion Courtiade, Jean-Marc Bonmatin, Patrice Marchand. Nano-détection du fipronil et de ses principaux métabolites dans diverses matrices apicoles. 1ere journée scientifique apicole, Feb 2009, Saint-Avold, France. ⟨hal-00742669⟩
  • J.M. Bonmatin, I. Moineau, Mélanie Colin, E.R. Bengsch. L'insecticide imidaclopride: biodisponibilité dans les sols et les plantes, toxicité et risque pour les abeilles. Conférence européenne sur les résidues de pesticides (EPRW, 2000), Jul 2000, York, Royaume-Uni. ⟨hal-02842868⟩

Poster3 documents

  • Camille Pasquet, Jean-Marc Bonmatin, Cyril Colas, Guillaume Gabant, Gaëtan Glauser, et al.. Exposition humaine aux fongicides SDHIs par les denrées alimentaires. 50e congrès du Groupe Français des Pesticides, May 2022, Namur, Belgique. 2022. ⟨hal-03870671⟩
  • S. Sobanska, N. Dupuy, J.M. Bonmatin. Raman characterization of pollen pellets collected by honey bees. Euroanalysis 2015, Sep 2015, Bordeaux, France. ⟨hal-01263522⟩
  • Delphine Paradis, Géraldine Bérail, Jean-Marc Bonmatin, Xavier Hirardot, Benjamin Poirot, et al.. Development of extraction and analytical methods by GC-MS2 and LC-MS2 in honey for 3 pesticide families (nicotinoids, pyrethroids and pyrazoles). Annual Meeting of the Doctoral School in Biological and Health Sciences, Jun 2011, Marseille, France. 1 p., 2011. ⟨hal-02805718⟩

Ouvrage (y compris édition critique et traduction)2 documents

  • Martine Regert (Dir.). Abeilles : une histoire intime avec l'humanité. Le Cherche-Midi; CNRS, pp.159, 2019, 978-2-7491-6224-9. ⟨hal-02918606⟩
  • Jean-Marc Bonmatin, Francisco Sánchez-Bayo, B. Janairo, Jose Isagani. Systemic Pesticides: A Worldwide Assessment. Jean-Marc Bonmatin, Francisco SÁnchez-Bayo, Jose Isagani B. Janairo. De La Salle Universyt Publishing House, 2017, 978-9715556484. ⟨hal-02071583⟩

Chapitre d'ouvrage4 documents

  • Camille Pasquet, Jean-Marc Bonmatin. Exposition humaine aux fongicides SDHI par les denrées alimentaires. Les éditions du GFP. Pesticides et agriculture durable comment les concilier ?, 2023, 978-2-9584232-0-9. ⟨hal-04308789⟩
  • Mehrnaz Katouzian-Safadi, Jean-Marc Bonmatin. Du Diagnostic Differential aux Therapies Prudentes : Le traité de la rougeole et de la variole de Râzi. Medicine and Healing in the Ancient Mediterranean World, D. Michaelides (Dir.),, Oxford & Philadelphia, Oxbow Books, pp.334-349, 2014. ⟨hal-01533047⟩
  • Jean-Marc Bonmatin, Patrice A. Marchand, Jean-François Cotte, Asmae Aajoud, Hervé Casabianca, et al.. Bees and systemic insecticides (imidacloprid, fipronil) in pollen: subnano-quantification by HPLC/MS/MS and GC/MS. A.A.M. Del Re; E. Capri; G. Fragoulis; M. Trevisan. Environmental Fate and Ecological Effects of Pesticides, pp.837-845, 2007. ⟨hal-00282377⟩
  • J.M. Bonmatin, I. Moineau, R. Charvet, M.E. Colin, C. Fléché, et al.. Behaviour of imidacloprid in fields. Toxicity for honey bees. E. Lichtfouse; J. Schwarzbauer; D. Robert. Environmental Chemistry. Green chemistry and pollutants in ecosystems, Springer, pp.483-494, 2005, 978-3-540-22860-8. ⟨10.1007/3-540-26531-7_44⟩. ⟨hal-00088509⟩

Autre publication4 documents

  • Jean-Marc Bonmatin, François Chamaraux, Laurence Huc, Séverine Jean. Impacts des pesticides SDHI sur l’environnement, la biodiversité et la santé humaine. 2024, 24 p. ⟨hal-05209661⟩
  • Jean-Marc Bonmatin, L.P. Belzunces, Cyril Vidau, Amélie Bajolet, Elodie Nguyen. TOXIBEES : METHODOLOGIE DE NOTATION DES MOLECULES DE L’OUTIL TOXIBEES. 2023. ⟨hal-04630350⟩
  • Jean-Marc Bonmatin. L'exposome pesticide que nous générons : un exemple neurotoxique au fil des recherches de l'abeille aux humains. 2022. ⟨hal-03870704⟩
  • Jean-Marc Bonmatin. One Health : pesticides, abeilles, animaux et humains. 2021. ⟨hal-03870714⟩

Pré-publication, Document de travail1 document

  • Lorenzo Furlan, Alberto Pozzebon, Carlo Duso, Noa Simon-Delso, Francisco Sánchez-Bayo, et al.. 浸透性殺虫剤に関する世界的な統合評価書(WIA)の更新版 第 3 部 浸透性殺虫剤に関する世界的な統合評価書(WIA)の更新版 第 3 部：浸透性殺虫剤の代替手段. 2020. ⟨hal-01966114⟩

Rapport3 documents

  • Robert Barouki, Jean-Pierre Cravedi, Philippe Quénel, Jeanne Garric, Alain Kaufmann, et al.. Intégration de l’exposome dans les activités de l’Anses. Saisine n°2022-METH-0197, Anses. 2023, 210 p. ⟨hal-04308854⟩
  • Pierre-Benoît Joly, Catherine Dargemont, Francine Behar-Cohen, Jean-Marc Bonmatin, Marion Desquilbet, et al.. La crédibilité de l’expertise scientifique - Enjeux et recommandations. Anses. 2022, 134 p. ⟨hal-04178142⟩
  • Pierre-Benoît Joly, Catherine Dargemont, Francine Behar-Cohen, Jean-Marc Bonmatin, Marion Desquilbet, et al.. La crédibilité de l’expertise scientifique. Enjeux et recommandations. ANSES. 2022. ⟨hal-04308885⟩

Documents récupérés de l'archive ouverte HAL logo

 

BERTRAND Marylène

email : marylene.bertrand[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.76.60

Engineer in chemical analysis within the  thematic group “NMR of biomolecules“

 


45 documents

Article dans une revue27 documents

  • Océane Quin, Marylène Bertrand, Pauline Gerardin, Philippe Gerardin, Christine Gerardin-Charbonnier, et al.. Antioxidant Impact of Soft Knotwood Extracts on Human Keratinocytes Shown by NMR Metabolomic Analysis. Journal of Proteome Research, 2025, 24 (4), pp.1745-1756. ⟨10.1021/acs.jproteome.4c00836⟩. ⟨hal-05203787⟩
  • Marylène Bertrand, Frédéric Szeremeta, Nadège Hervouet-Coste, Vincent Sarou-Kanian, Céline Landon, et al.. An adult Drosophila glioma model to highlight metabolic dysfunctions and evaluate the role of the serotonin 5‐HT 7 receptor as a potential therapeutic target. FASEB Journal, 2023, 37 (11), ⟨10.1096/fj.202300783RR⟩. ⟨hal-04301912⟩
  • Marion Maravat, Marylène Bertrand, Céline Landon, Franck Fayon, Séverine Morisset-Lopez, et al.. Complementary Nuclear Magnetic Resonance-Based Metabolomics Approaches for Glioma Biomarker Identification in a Drosophila melanogaster Model. Journal of Proteome Research, 2021, 20 (8), pp.3977-3991. ⟨10.1021/acs.jproteome.1c00304⟩. ⟨hal-03335927⟩
  • Marylène Bertrand, Martine Decoville, Herve Meudal, Serge Birman, Celine Landon. Metabolomic Nuclear Magnetic Resonance Studies at Presymptomatic and Symptomatic Stages of Huntington’s Disease on a Drosophila Model. Journal of Proteome Research, 2020, 19 (10), pp.4034-4045. ⟨10.1021/acs.jproteome.0c00335⟩. ⟨hal-02968233⟩
  • H Blasco, C Veyrat-Durebex, M Bertrand, F Patin, F Labarthe, et al.. A Multiplatform Metabolomics Approach to Characterize Plasma Levels of Phenylalanine and Tyrosine in Phenylketonuria.. JIMD reports, 2017, pp.69-79. ⟨10.1007/8904_2016_568⟩. ⟨hal-01622559⟩
  • R. Demets, M. Bertrand, A. Bolkhovitinov, K. Bryson, C. Colas, et al.. Window contamination on Expose-R. International Journal of Astrobiology, 2015, 14 (1), pp.33-45. ⟨10.1017/S1473550414000536⟩. ⟨hal-04270210⟩
  • Hervé Cottin, K. Saiagh, Y.Y. Guan, M. Cloix, D. Khalaf, et al.. The AMINO experiment: a laboratory for astrochemistry and astrobiology on the EXPOSE-R facility of the International Space Station. International Journal of Astrobiology, 2015, 14 (01), pp.67-77. ⟨10.1017/S1473550414000500⟩. ⟨hal-01107510⟩
  • Marylène Bertrand, Annie Chabin, Cyril Colas, Martine Cadène, Didier Chaput, et al.. The AMINO experiment: exposure of amino acids in the EXPOSE-R experiment on the International Space Station and in laboratory. International Journal of Astrobiology, 2015, 14 (01), pp.89-97. ⟨10.1017/S1473550414000354⟩. ⟨hal-01170486⟩
  • Frances Westall, Frédéric Foucher, Nicolas Bost, Marylène Bertrand, Damien Loizeau, et al.. Biosignatures on Mars: What, Where, and How? Implications for the Search for Martian Life. Astrobiology, 2015, 15 (11), pp.998-1029. ⟨10.1089/ast.2015.1374⟩. ⟨insu-01234353⟩
  • Hervé Cottin, Kafila Saiagh, D. Nguyen, Noël Grand, Yves Bénilan, et al.. Photochemical studies in low Earth orbit for organic compounds related to small bodies, Titan and Mars. Current and future facilities.. Bulletin de la Société Royale des Sciences de Liège, 2015, 84, pp.60 - 73. ⟨hal-01110518⟩
  • Francès Westall, Damien Loizeau, Frédéric Foucher, Nicolas Bost, Marylène Bertrand, et al.. Habitability on Mars from a Microbial Point of View. Astrobiology, 2013, 13 (9), pp.887-897. ⟨10.1089/ast.2013.1000⟩. ⟨insu-00866015⟩
  • Marylène Bertrand, Annie Chabin, André Brack, H. Cottin, D. Chaput, et al.. The PROCESS Experiment: Exposure of Amino Acids in the EXPOSE-E Experiment on the International Space Station and in Laboratory Simulations.. Astrobiology, 2012, 12 (5), pp.426-35. ⟨10.1089/ast.2011.0755⟩. ⟨hal-00721777⟩
  • Hervé Cottin, Yuan Yong Guan, Audrey Noblet, Olivier Poch, Kafila Saiagh, et al.. The PROCESS Experiment: An Astrochemistry Laboratory for Solid and Gaseous Organic Samples in Low-Earth Orbit. Astrobiology, 2012, 12 (5), pp.412-425. ⟨10.1089/ast.2011.0773⟩. ⟨hal-00710533⟩
  • Pierre de Marcellus, Marylène Bertrand, Michel Nuevo, Frances Westall, Louis Le Sergeant D’hendecourt. Prebiotic significance of extraterrestrial ice photochemistry: detection of hydantoin in organic residues.. Astrobiology, 2011, 11 (9), pp.847-54. ⟨10.1089/ast.2011.0677⟩. ⟨hal-00720601⟩
  • Marylène Bertrand, Sjerry van Der Gaast, Faith Vilas, Friedrich Hoerz, Gerald Haynes, et al.. The Fate of Amino Acids During Simulated Meteoritic Impact. Astrobiology, 2009, 9 (10), pp.943-951. ⟨10.1089/ast.2008.0327⟩. ⟨hal-00521727⟩
  • Marylène Bertrand, Sjerry van Der Gaast, Faith Vilas, Friedrich Hörz, Gerald Haynes, et al.. Effect of impact shock simulation on amino acids. Origins of Life and Evolution of Biospheres, 2009, 393, pp.52-53. ⟨hal-00527525⟩
  • Annie Chabin, Marylène Bertrand, André Brack, H. Cottin, Frances Westall. Exposure of Amino Acids on the International Space Station: EXPOSE-Eutef and EXPOSE-R. Origins of Life and Evolution of Biospheres, 2009, 39 (3-4 Sp. Iss. SI), pp.352-353. ⟨hal-00521873⟩
  • Hervé Cottin, Patrice Coll, David Coscia, Nicolas Fray, Yuan Yong Guan, et al.. Heterogeneous solid/gas chemistry of organic compounds related to comets, meteorites, Titan and Mars: laboratory and in lower Earth orbit experiments. Advances in Space Research, 2008, 42 (12), pp.2019-2035. ⟨10.1016/j.asr.2007.09.017⟩. ⟨hal-00339783⟩
  • Marylène Bertrand, Annie Chabin, André Brack, Frances Westall. Separation of amino acid enantiomers via chiral derivatization and non chiral column by gas chromatography. Journal of Chromatography A, 2008, 1180 (1-2), pp.131-137. ⟨10.1016/j.chroma.2007.12.004⟩. ⟨hal-00282553⟩
  • C. Buré, O. Boujard, M. Bertrand, C. Lange, A.F. Delmas. Letter: Collision-induced dissociation of peptide thioesters: influence of the peptide length on the fragmentation. European Journal of Mass Spectrometry, 2005, 11, pp.31-34. ⟨hal-00088531⟩
  • F. Boillot, A. Chabin, C. Buré, M. Venet, A. Belsky, et al.. The PERSEUS-Exobiology experiment on board MIR. Origins of Life and Evolution of the Biosphere, 2002, 32 (4), pp.359-385. ⟨10.1023/A:1020501226958⟩. ⟨hal-02104813⟩
  • Marylène Bertrand, André Brack. Conformational Transition of Acidic Peptides Exposed to Minerals in Suspension. Chemistry - A European Journal, 2000, 6 (18), pp.3452-3455. ⟨10.1002/1521-3765(20000915)6:18<3452::AID-CHEM3452>3.0.CO;2-T⟩. ⟨hal-02106710⟩
  • Bernard Barbier, Marylène Bertrand, François Boillot, Annie Chabin, Didier Chaput, et al.. Delivery of extraterrestrial amino acids to the primitive Earth. Exposure experiments in Earth orbit.. Biological Sciences in Space, 1998, 12 (2), pp.92-95. ⟨10.2187/bss.12.92⟩. ⟨hal-02106435⟩
  • Marylène Bertrand, André Brack. Preferential beta-sheet structuration of multiconformational poly(Glu-Leu) by metallic ions. Letters in Peptide Science, 1997, 4 (4/6), pp.387-389. ⟨10.1023/A:1008877728409⟩. ⟨hal-02104833⟩
  • Marylène Bertrand, A. Brack. Conformational variety of polyanionic peptides at low salt concentrations.. Origins of Life and Evolution of Biospheres, 1996, 27 (5-6), pp.585-95. ⟨hal-02104860⟩
  • Marylène Bertrand, Denise Sy, André Brack. Salt-dependent conformational diversity of alternating poly (Glu-Leu). The Journal of Peptide Research, 1996, 49 (3), pp.269-272. ⟨10.1111/j.1399-3011.1997.tb00886.x⟩. ⟨hal-02104850⟩
  • Josette Verhaeghe, Eric Lacassie, Marylène Bertrand, Yves Trudelle. A new route to sequential polypeptides combining solid phase synthesis and solution peptide synthesis. Tetrahedron Letters, 1992, 34 (3), pp.461-464. ⟨10.1016/0040-4039(93)85102-3⟩. ⟨hal-02104862⟩

Communication dans un congrès2 documents

  • Marylène Bertrand, H. Meudal, S. Birman, M. Decoville, C. Landon. Metabolomic NMR studies & Huntington’s disease: models in transgenic drosophila. Conférence SMMAP 2017 - Conférence de Spectrométrie de Masse, Métabolomique et Fluxomique & Electrophorèse et Analyse Protéomique, Oct 2017, Marne-la-Vallée, France. ⟨hal-02919162⟩
  • H. Cottin, Y. Y. Guan, Patrice Coll, David Coscia, N. Fray, et al.. Astrochemistry on the EXPOSE/ISS and BIOPAN/Foton experiments. Highlights of Astronomy H15, Proceedings of the International Astronomical Union, XXVIIth IAU General Assembly, 2009, Rio de Janeiro, Brazil. pp.384-385, ⟨10.1017/S174392131001094X⟩. ⟨hal-00531605⟩

Poster14 documents

  • David Gosset, Julien Sobilo, Herve Meudal, Frederic Szeremeta, Marylène Bertrand, et al.. Plateforme MO2VING: from MOlecular Organization to in Vivo ImagiNG. 34ème Colloque Biotechnocentre, Oct 2022, Nouan Le Fuzelier, France. ⟨hal-03863246⟩
  • Marylène Bertrand, Vidian De Concini, Rania Boussad, Céline Landon, Arnaud Menuet. NMR metabolomic analysis: an aid to understanding neuroinflammatory processes in nociceptive defects of Fmr1 KO mice, model of Fragile X syndrome. 14es journées scientifiques RFMF, Nov 2021, Aussois, France. ⟨hal-03616628⟩
  • Marion Maravat, Marylène Bertrand, M. Decoville, C. Landon, Séverine Morisset-Lopez, et al.. Biomarkers involved in glioma development in Drosophila melanogaster model. European RFMF Metabomeeting 2020, Jan 2020, Toulouse, France. ⟨hal-02919170⟩
  • Marylène Bertrand, M. Decoville, H. Meudal, S. Birman, C. Landon. Metabolomic NMR studies at presymptomatic and symptomatic stages of Huntington’s disease, on drosophila model. 12es journées scientifiques du Réseau Francophone de Métabolomique et de Fluxomique, May 2019, Clermont-Ferrand, France. ⟨hal-02919883⟩
  • Marylène Bertrand, M. Decoville, H. Meudal, S. Birman, C. Landon. Metabolomic NMR studies at presymptomatic and symptomatic stages of Huntington’s disease, on drosophila model. 20th annual meeting of Invertebrate Neurobiology, May 2019, Orléans, France. ⟨hal-02919877⟩
  • Marion Maravat, Marylène Bertrand, M. Decoville, C. Landon, F. Fayon, et al.. Biomarkers involved in glioma development in Drosophila melanogaster model. 12es journées scientifiques du Réseau Francophone de Métabolomique et de Fluxomique, May 2019, Clermont-Ferrand, France. ⟨hal-02919890⟩
  • Marion Maravat, Martine Decoville, Marylène Bertrand, Celine Landon, Séverine Morisset-Lopez, et al.. NMR-based metabolomics for glioma biomarker discovery in a Drosophila melanogaster model. 3rd edition Metabolism & Cancer, Apr 2019, Marseille, France. ⟨hal-02986792⟩
  • Marion Maravat, Marylène Bertrand, S. Morisset-Lopez, F. Fayon, V. Sarou-Kanian, et al.. Identification de biomarqueurs impliqués dans le développement de gliomes dans un modèle développé chez la drosophile. 13es Journées Canceropôle Grand-Ouest, Jul 2019, Tours, France. ⟨hal-02919893⟩
  • Marylène Bertrand, M. Decoville, H. Meudal, S. Birman, C. Landon. Huntington’s disease: metabolomic studies by NMR analyzes on Drosophila Model. 11es Journées du Réseau francophone de métabolomique et de fluxomique, May 2018, Liège, Belgium. ⟨hal-02919911⟩
  • Marylène Bertrand, M. Decoville, H. Meudal, S. Birman, C. Landon. NMR metabolimics to detect Huntington’s disease at early stage. 28th ICMRBS - International Council on Magnetic Resonance in Biological Systems, Aug 2018, Dublin, Ireland. ⟨hal-02919924⟩
  • Marylène Bertrand, H. Meudal, M. Decoville, C. Landon. Prediction of Huntingon's Disease by Metabolomic NMR Analyzes: Studies in Drosophila Model. NMR: a tool for biology Xth, Jan 2017, Paris, France. ⟨hal-02919990⟩
  • Marylène Bertrand, Hervé Meudal, Florence Bordères, Vincent Furstoss, Louis Wozniak, et al.. Etude de la fertilité chez le bouc : analyse métabolomique par RMN. 10. Journées scientifiques du Réseau Francophone de Métabolomique et Fluxomique RFMF 2016, May 2016, Montpellier, France. 155 p., 2016, 10 JS Réseau Francophone de Métabolique et Fluxomique. ⟨hal-01581541⟩
  • H. Meudal, Marylène Bertrand, Laurence Jouvensal, A.F. Delmas, Françoise Paquet, et al.. La résonance Magnétique Nucléaire pour la chimie et la biologie. 29e colloque Biotechnocentre, Oct 2016, Seillac, France. ⟨hal-02920143⟩
  • Marylène Bertrand, H. Meudal, M. Decoville, C. Landon. La RMN, un outil pour la métabolomique. 29e colloque Biotechnocentre, Oct 2016, Seillac, France. ⟨hal-02453360⟩

Chapitre d'ouvrage1 document

  • Marylène Bertrand, Corinne Buré, Fabrice Fleury, André Brack. Prebiotic polymerization of amino acid thioesters on mineral surfaces. Geochemistry and the Origin of Life, Universal Academy Press, 2002. ⟨hal-03616744⟩

Rapport1 document

  • Balan Lavinia, Marylène Bertrand, Roberta Bongiovanni, Catherine Debiemme-Chouvy, Marie-Hélène Delville, et al.. Rapport de Prospective 2023 du Conseil Scientifique de l'Institut de Chimie du CNRS (Mandature 2019-2023). Centre national de la recherche scientifique (CNRS). 2023. ⟨hal-04307872v2⟩

Documents récupérés de l'archive ouverte HAL logo

BÉNÉDETTI Hélène

email : helene.benedetti[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.55.84

Research director, CBM Deputy scientific director, co-coordinator of the Department “Cell biology, Molecular Targets and innovative therapies” and co-responsible of the Team “Cell signalling and neurofibromatosis”

 


126 documents

Article dans une revue67 documents

  • Anthony Champiré, Rayan Berabez, Abdennour Braka, Aurélie Cosson, Justine Corret, et al.. Tetrahydropyridine LIMK inhibitors: Structure activity studies and biological characterization. European Journal of Medicinal Chemistry, 2024, 271, pp.116391-116391. ⟨10.1016/j.ejmech.2024.116391⟩. ⟨hal-04575964⟩
  • Mohammed Bergoug, Christine Mosrin-Huaman, Amandine Serrano, Fabienne Godin, Michel Doudeau, et al.. An Atypical Mechanism of SUMOylation of Neurofibromin SecPH Domain Provides New Insights into SUMOylation Site Selection. Journal of Molecular Biology, 2024, 436 (22), pp.168768. ⟨10.1016/j.jmb.2024.168768⟩. ⟨hal-04771131⟩
  • Hélène Bénédetti, Béatrice Vallée. LIM Kinases: From Molecular to Pathological Features. Cells, 2023, 12 (12), pp.1649. ⟨10.3390/cells12121649⟩. ⟨hal-04208415⟩
  • Elodie Villalonga, Christine Mosrin, Thierry Normand, Caroline Girardin, Amandine Serrano, et al.. LIM Kinases, LIMK1 and LIMK2, Are Crucial Node Actors of the Cell Fate: Molecular to Pathological Features. Cells, 2023, 12 (5), pp.805. ⟨10.3390/cells12050805⟩. ⟨hal-04208405⟩
  • Rayan Berabez, Sylvain Routier, Hélène Bénédetti, Karen Plé, Béatrice Vallée. LIM kinases, promising but reluctant therapeutic targets: chemistry and preclinical validation in vivo. Cells, 2022, 11 (13), pp.2090. ⟨10.3390/cells11132090⟩. ⟨hal-03721458⟩
  • Bojan Žunar, Christine Mosrin-Huaman, Hélène Bénédetti, Béatrice Vallée. Re-engineering of CUP1 promoter and Cup2/Ace1 transactivator to convert Saccharomyces cerevisiae into a whole-cell eukaryotic biosensor capable of detecting 10 nM of bioavailable copper. Biosensors and Bioelectronics, 2022, 214, pp.114502. ⟨10.1016/j.bios.2022.114502⟩. ⟨hal-03820214⟩
  • Wissem Deraredj Nadim, Shalina Hassanaly, Hélène Bénédetti, Claudine Kieda, Catherine Grillon, et al.. The GTPase-activating protein-related domain of neurofibromin interacts with MC1R and regulates pigmentation-mediated signaling in human melanocytes. Biochemical and Biophysical Research Communications, 2021, 534, pp.758-764. ⟨10.1016/j.bbrc.2020.11.003⟩. ⟨hal-03007433⟩
  • Frédéric Buron, Nuno Rodrigues, Thibault Saurat, Marie-Aude Hiebel, Stéphane Bourg, et al.. Design, Synthesis and SAR in 2,4,7-Trisubstituted Pyrido[3,2-d]Pyrimidine Series as Novel PI3K/mTOR Inhibitors. Molecules, 2021, 26 (17), pp.5349. ⟨10.3390/molecules26175349⟩. ⟨hal-03348966⟩
  • Skander A Abboud, Hadji H., Michel Doudeau, Hélène Bénédetti, Vincent Aucagne. A straightforward methodology to overcome solubility challenges for N-terminal cysteinyl peptide segments used in native chemical ligation. Chemical Science, 2021, 12, pp.3194 - 3201. ⟨10.1039/d0sc06001a⟩. ⟨hal-03447239⟩
  • Mohammed Bergoug, Michel Doudeau, Fabienne Godin, Christine Mosrin-Huaman, Béatrice Vallée, et al.. Neurofibromin Structure, Functions and Regulation. Cells, 2020, 9, ⟨10.3390/cells9112365⟩. ⟨hal-03070759v2⟩
  • Béatrice Vallée, Michel Doudeau, Fabienne Godin, Hélène Bénédetti. Characterization at the Molecular Level using Robust Biochemical Approaches of a New Kinase Protein. Journal of visualized experiments : JoVE, 2019, 148, pp.e59820. ⟨10.3791/59820⟩. ⟨hal-02282630⟩
  • Julie Tastet, Hélène Cuberos, Béatrice Vallée, Annick Toutain, Martine Raynaud, et al.. LIMK2-1 is a Hominidae-Specific Isoform of LIMK2 Expressed in Central Nervous System and Associated with Intellectual Disability. Neuroscience, 2019, 399, pp.199-210. ⟨10.1016/j.neuroscience.2018.12.017⟩. ⟨hal-02067472⟩
  • Béatrice Vallée, Hélène Cuberos, Michel Doudeau, Fabienne Godin, David Gosset, et al.. LIMK2-1, a new isoform of human LIMK2, regulates actin cytoskeleton remodeling via a different signaling pathway than that of its two homologs, LIMK2a and LIMK2b. Biochemical Journal, 2018, 475 (23), pp.3745-3761. ⟨hal-01966439⟩
  • Viorel Simion, Wissem Deraredj Nadim, Hélène Bénédetti, Chantal Pichon, Séverine Morisset-Lopez, et al.. Pharmacomodulation of microRNA Expression in Neurocognitive Diseases: Obstacles and Future Opportunities. Current Neuropharmacology, 2017, 15 (2), pp.276 - 290. ⟨10.2174/1570159X14666160630210422⟩. ⟨hal-01618771⟩
  • Wissem Deraredj Nadim, Simion Viorel, Hélène Bénédetti, Chantal Pichon, Patrick Baril, et al.. MicroRNAs in Neurocognitive Dysfunctions: New Molecular Targets for Pharmacological Treatments?. Current Neuropharmacology, 2017, 15 (2), pp.260 - 275. ⟨10.2174/1570159X14666160709001441⟩. ⟨hal-01618199⟩
  • Wissem Deraredj Nadim, Séverine Chaumont-Dubel, Fahima Madouri, Laetitia Cobret, Marie-Ludivine de Tauzia, et al.. Physical interaction between neurofibromin and serotonin 5-HT 6 receptor promotes receptor constitutive activity. Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (43), pp.12310 - 12315. ⟨10.1073/pnas.1600914113⟩. ⟨hal-01407899⟩
  • L Cobret, M L de Tauzia, J Ferent, E Traiffort, I Hénaoui, et al.. Targeting the cis-dimerization of LINGO-1 with low MW compounds affects its downstream signalling. British Journal of Clinical Pharmacology, 2015, 172 (3), pp.841-856. ⟨10.1111/bph.12945⟩. ⟨hal-01170735⟩
  • H. Cuberos, B. Vallée, P. Vourc'H, J. Tastet, C.R. Andres, et al.. Roles of LIM kinases in central nervous system function and dysfunction. FEBS Letters, 2015, 589 (24PartB), pp.3795-3806. ⟨10.1016/j.febslet.2015.10.032⟩. ⟨hal-02072231⟩
  • Julie Tastet, Loïc Decalonne, Sylviane Marouillat, Joëlle Malvy, Rose-Anne Thépault, et al.. Mutation screening of the ubiquitin ligase gene RNF135 in French patients with autism. Psychiatric Genetics, 2015, 25 (6), pp.263-267. ⟨10.1097/ypg.0000000000000100⟩. ⟨hal-02072312⟩
  • Solene Guiheneuf, Ludovic Paquin, Francois Carreaux, Emilie Durieu, Helene Benedetti, et al.. Microwave Assisted Organic Synthesis (MAOS) of New Dispacamide A Derivatives Bearing a Thiazolinone Platform, Biological Assays on Inhibition of Protein Kinases and Cell Effects. Current microwave chemistry, 2014, 1 (1), pp.33-40. ⟨10.2174/22133356114019990002⟩. ⟨hal-01114583⟩
  • Amélie Bruel, Romain Beneteau, Mylène Chabanne, Olivier Lozach, Rémy Le Guevel, et al.. Synthesis of new pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs as DYRK1A inhibitors. Bioorganic and Medicinal Chemistry Letters, 2014, 24 (21), pp.5037 - 5040. ⟨10.1016/j.bmcl.2014.09.017⟩. ⟨hal-01086026⟩
  • Reine Nehmé, Hala Nehmé, Thibault Saurat, Marie-Ludivine De-Tauzia, Frédéric Buron, et al.. New in-capillary electrophoretic kinase assays to evaluate inhibitors of the PI3k/Akt/mTOR signaling pathway. Analytical and Bioanalytical Chemistry, 2014, 406 (15), pp.3743-3754. ⟨10.1007/s00216-014-7790-z⟩. ⟨hal-01180770⟩
  • Thibault Saurat, Frédéric Buron, Nuno Rodrigues, Marie-Ludivine de Tauzia, Lionel Colliandre, et al.. Design, Synthesis, and Biological Activity of Pyridopyrimidine Scaffolds as Novel PI3K/mTOR Dual Inhibitors. Journal of Medicinal Chemistry, 2014, 57 (3), pp.613-631. ⟨10.1021/jm401138v⟩. ⟨hal-01180887⟩
  • François Hericourt, François Chefdor, Lucie Bertheau, Mirai Tanigawa, Tatsuya Maeda, et al.. Characterization of histidine-aspartate kinase HK1 and identification of histidine phosphotransfer proteins as potential partners in a Populus multistep phosphorelay. Physiologia Plantarum, 2013, 149 (2), pp.188-199. ⟨10.1111/ppl.12024⟩. ⟨hal-02070851⟩
  • Béatrice Vallée, Michel Doudeau, Fabienne Godin, Aurélie Gombault, Aurélie Tchalikian-Cosson, et al.. Nf1 RasGAP Inhibition of LIMK2 Mediates a New Cross-Talk between Ras and Rho Pathways. PLoS ONE, 2012, 7 (10), pp.e47283. ⟨10.1371/journal.pone.0047283⟩. ⟨hal-03054185⟩
  • Dominique Arnaud, Annabelle Déjardin, Jean-Charles Leplé, Marie-Claude Lesage-Descauses, Nathalie Boizot, et al.. Expression analysis of LIM gene family in poplar, toward an updated phylogenetic classification.. BMC Research Notes, 2012, 5, pp.102. ⟨10.1186/1756-0500-5-102⟩. ⟨hal-00721759⟩
  • A. Bruel, Cedric Logé, M.-L. de Tauzia, M. Ravache, Ronan Le Guével, et al.. Synthesis and biological evaluation of new 5-benzylated 4-oxo-3,4-dihydro-5Hpyridazino[4,5-b]indoles as PI3Ka inhibitors.. European Journal of Medicinal Chemistry, 2012, 57, pp.225-233. ⟨hal-00764872⟩
  • Martine Beaufour, Fabienne Godin, Béatrice Vallée, Martine Cadene, Hélène Bénédetti. Interaction Proteomics Suggests a New Role for the Tfs1 Protein in Yeast.. Journal of Proteome Research, 2012, 11 (6), pp.3211-3218. ⟨10.1021/pr201239t⟩. ⟨hal-00721771⟩
  • Julie Tastet, Patrick Vourc'H, Frédéric Laumonnier, Béatrice Vallée, Carole Michelle, et al.. LIMK2d, a truncated isoform of Lim kinase 2 regulates neurite growth in absence of the LIM kinase domain. Biochemical and Biophysical Research Communications, 2012, 420 (2), pp.247-252. ⟨10.1016/j.bbrc.2012.02.134⟩. ⟨hal-01136281⟩
  • Fabienne Godin, Sandrine Villette, Béatrice Vallée, Michel Doudeau, Séverine Morisset-Lopez, et al.. A fraction of neurofibromin interacts with PML bodies in the nucleus of the CCF astrocytoma cell line.. Biochemical and Biophysical Research Communications, 2012, 418 (4), pp.689-94. ⟨10.1016/j.bbrc.2012.01.079⟩. ⟨hal-00721861⟩
  • Aurélie Gombault, Jonas Warringer, Robert Caesar, Fabienne Godin, Béatrice Vallée, et al.. A phenotypic study of TFS1 mutants differentially altered in the inhibition of Ira2p or CPY. FEMS Yeast Research, 2009, 9 (6), pp.867-874. ⟨10.1111/j.1567-1364.2009.00535.x⟩. ⟨hal-00522432⟩
  • Aurélie Gombault, Fabienne Godin, Denise Sy, Baptiste Legrand, Hélène Chautard, et al.. Molecular Basis of the Tfs1/Ira2 Interaction: A Combined Protein Engineering and Molecular Modelling Study. Journal of Molecular Biology, 2007, 374 (3), pp.604-617. ⟨10.1016/j.jmb.2007.09.057⟩. ⟨hal-00181161⟩
  • F. Chefdor, H. Bénédetti, C. Depierreux, Franck Delmotte, D. Morabito, et al.. Osmotic stress sensing in Populus: components identification of a phosphorelay system. FEBS Letters, 2006, 580 (1), pp.77-81. ⟨10.1016/j.febslet.2005.11.051⟩. ⟨hal-00088838⟩
  • S. Quevillon-Cheruel, N. Leulliot, M. Graille, N. Hervouet, F. Coste, et al.. Crystal structure of yeast YHR049W/FSH1, a member of the serine hydrolase family. Protein science : a publication of the Protein Society., 2005, 14, pp.1350-1356. ⟨hal-00088667⟩
  • S. Castella, Hélène Bénédetti, R. de Llorens, J.L. Dacheux, F. Dacheux. Train A, an RNase-A-like protein without RNase activity is secreted and reabsorbed by the same epididymal cells under testicular control. Biology of Reproduction, 2004, 71 (5), pp.1677-1687. ⟨10.1095/biolreprod.104.031666⟩. ⟨hal-00112960⟩
  • H. Chautard, M. Jacquer, F. Schoentgen, N. Bureaud, H. Bénédetti. Tfs1, a member of the PEBP family, inhibits the Ira2p but not the Ira1p Ras GTPase activating protein in Saccharomyces cerevisiae. Eukaryotic Cell, 2004, 3 (2), pp.459-470. ⟨10.1128/EC.3.2.459-470.2004⟩. ⟨hal-00112967⟩
  • Emmanuelle Bouveret, Laure Journet, Anne Walburger, E. Cascales, Hélène Bénédetti, et al.. Analysis of the Escherichia coli Tol-Pal and TonB systems by periplasmic production of Tol, TonB, colicin, or phage capsid soluble domains.. Biochimie, 2002, 84 (5-6), pp.413-21. ⟨hal-02130103⟩
  • Laure Journet, E. Bouveret, A. Rigal, R Lloubes, C Lazdunski, et al.. Import of colicins across the outer membrane of Escherichia coli involves multiple protein interactions in the periplasm.. Molecular Microbiology, 2001, 42 (2), pp.331-44. ⟨hal-02130124⟩
  • Laurence Serre, F Serre, Charles Zelwer, Nicole Bureaud, Francoise Schoentgen, et al.. Crystal structures of YBHB and YBCL from Escherichia coli , two bacterial homologues to a Raf kinase inhibitor protein 1 1Edited by R. Huber. Journal of Molecular Biology, 2001, 310 (3), pp.617-634. ⟨10.1006/jmbi.2001.4784⟩. ⟨hal-02130120⟩
  • C. Lazdunski, E. Bouveret, A Rigal, Laure Journet, R. Lloubes, et al.. Colicin import into Escherichia coli cells requires the proximity of the inner and outer membranes and other factors. International Journal of Medical Microbiology, 2000, 290 (4-5), pp.337-344. ⟨10.1016/S1438-4221(00)80037-5⟩. ⟨hal-02130686⟩
  • E Bouveret, H Bénédetti, A Rigal, E. Loret, C Lazdunski. In vitro characterization of peptidoglycan-associated lipoprotein (PAL)-peptidoglycan and PAL-TolB interactions.. Journal of Bacteriology, 1999, 181 (20), pp.6306-11. ⟨hal-02130134⟩
  • Laure Journet, A Rigal, C Lazdunski, H Bénédetti. Role of TolR N-terminal, central, and C-terminal domains in dimerization and interaction with TolA and tolQ.. Journal of Bacteriology, 1999, 181 (15), pp.4476-84. ⟨hal-02130149⟩
  • Chantal Abergel, E. Bouveret, J.M Claverie, K Brown, A Rigal, et al.. Structure of the Escherichia coli TolB protein determined by MAD methods at 1.95 A resolution.. Structure, 1999, 7 (10), pp.1291-300. ⟨hal-02130130⟩
  • Chantal Abergel, A Rigal, S Chenivesse, C Lazdunski, J.M Claverie, et al.. Crystallization and preliminary crystallographic study of a component of the Escherichia coli tol system: TolB.. Acta crystallographica Section D : Structural biology [1993-..], 1998, 54 (Pt 1), pp.102-4. ⟨hal-02130160⟩
  • C.J Lazdunski, E. Bouveret, A. Rigal, Laure Journet, R Lloubès, et al.. Colicin import into Escherichia coli cells.. Journal of Bacteriology, 1998, 180 (19), pp.4993-5002. ⟨hal-02130152⟩
  • E Bouveret, A Rigal, C Lazdunski, H Bénédetti. Distinct regions of the colicin A translocation domain are involved in the interaction with TolA and TolB proteins upon import into Escherichia coli.. Molecular Microbiology, 1998, 27 (1), pp.143-57. ⟨hal-02130155⟩
  • E Bouveret, A Rigal, C Lazdunski, H Bénédetti. The N-terminal domain of colicin E3 interacts with TolB which is involved in the colicin translocation step.. Molecular Microbiology, 1997, 23 (5), pp.909-20. ⟨hal-02130173⟩
  • A Rigal, E. Bouveret, R Lloubes, C Lazdunski, H Bénédetti. The TolB protein interacts with the porins of Escherichia coli.. Journal of Bacteriology, 1997, 179 (23), pp.7274-7279. ⟨10.1128/jb.179.23.7274-7279.1997⟩. ⟨hal-02130169⟩
  • R Derouiche, M Gavioli, H Bénédetti, A Prilipov, C Lazdunski, et al.. TolA central domain interacts with Escherichia coli porins.. EMBO Journal, 1996, 15 (23), pp.6408-15. ⟨hal-02130175⟩
  • R Derouiche, H Bénédetti, Jc Lazzaroni, C Lazdunski, R Lloubès. Protein complex within Escherichia coli inner membrane. TolA N-terminal domain interacts with TolQ and TolR proteins. Journal of Biological Chemistry, 1995, 270 (19), pp.11078-11084. ⟨10.1074/jbc.270.19.11078⟩. ⟨hal-02130187⟩
  • Denis Duché, L. Letellier, V. Geli, H. Bénédetti, D. Baty. Quantification of group A colicin import sites.. Journal of Bacteriology, 1995, 177 (17), pp.4935-4939. ⟨10.1128/jb.177.17.4935-4939.1995⟩. ⟨hal-02440962⟩
  • Denis Duché, L. Letellier, V Géli, H Bénédetti, D. Baty. Quantification of group A colicin import sites.. Journal of Bacteriology, 1995, 177 (17), pp.4935-4939. ⟨10.1128/jb.177.17.4935-4939.1995⟩. ⟨hal-02130183⟩
  • Jean Claude Lazzaroni, Anne Vianney, V Vianney, Jean Luc Popot, Hélène Bénédetti, et al.. Transmembrane α-Helix Interactions are Required for the Functional Assembly of theEscherichia coliTol Complex. Journal of Molecular Biology, 1995, 246 (1), pp.1-7. ⟨10.1006/jmbi.1994.0058⟩. ⟨hal-02130202⟩
  • E. Bouveret, R Derouiche, R. Rigal, R Lloubès, C Lazdunski, et al.. Peptidoglycan-associated lipoprotein-TolB interaction. A possible key to explaining the formation of contact sites between the inner and outer membranes of Escherichia coli. Journal of Biological Chemistry, 1995, 270 (19), pp.11071-11077. ⟨10.1074/jbc.270.19.11071⟩. ⟨hal-02130195⟩
  • David Espesset, Yves Corda, Kyle Cunningham, Hélène Bénédetti, Roland Lloubes, et al.. The colicin A pore-forming domain fused to mitochondrial intermembrane space sorting signals can be functionally inserted into the Escherichia coli plasma membrane by a mechanism that bypasses the Tol proteins. Molecular Microbiology, 1994, 13 (6), pp.1121-1131. ⟨10.1111/j.1365-2958.1994.tb00503.x⟩. ⟨hal-02130213⟩
  • G. Guihard, P. Boulanger, H Bénédetti, R Lloubés, M Besnard, et al.. Colicin A and the Tol proteins involved in its translocation are preferentially located in the contact sites between the inner and outer membranes of Escherichia coli cells.. Journal of Biological Chemistry, 1994, 269 (8), pp.5874-80. ⟨hal-02130218⟩
  • H Bénédetti, S Raths, F Crausaz, H. Riezman. The END3 gene encodes a protein that is required for the internalization step of endocytosis and for actin cytoskeleton organization in yeast.. Molecular Biology of the Cell, 1994, 5 (9), pp.1023-37. ⟨hal-02130204⟩
  • G. Guihard, H Bénédetti, M Besnard, L. Letellier. Phosphate efflux through the channels formed by colicins and phage T5 in Escherichia coli cells is responsible for the fall in cytoplasmic ATP.. Journal of Biological Chemistry, 1993, 268 (24), pp.17775-80. ⟨hal-02130233⟩
  • V Geli, R Lloubes, S Zaat, R van Spaendonk, C Rollin, et al.. Recognition of the colicin A N-terminal epitope 1C11 in vitro and in vivo in Escherichia coli by its cognate monoclonal antibody. FEMS Microbiology Letters, 1993, 109 (2-3), pp.335-342. ⟨10.1016/0378-1097(93)90042-z⟩. ⟨hal-02130222⟩
  • J Rohrer, H Bénédetti, B Zanolari, H. Riezman. Identification of a novel sequence mediating regulated endocytosis of the G protein-coupled alpha-pheromone receptor in yeast.. Molecular Biology of the Cell, 1993, 4 (5), pp.511-21. ⟨hal-02130242⟩
  • Hélène Bénédetti, R Lloubès, C Lazdunski, L. Letellier. Colicin A unfolds during its translocation in Escherichia coli cells and spans the whole cell envelope when its pore has formed.. EMBO Journal, 1992, 11 (2), pp.441-7. ⟨hal-02130272⟩
  • Hélène Bénédetti, C Lazdunski, R Lloubès. Protein import into Escherichia coli: colicins A and E1 interact with a component of their translocation system.. EMBO Journal, 1991, 10 (8), pp.1989-95. ⟨hal-02130277⟩
  • Hélène Bénédetti, M Frenette, D. Baty, M Knibiehler, F. Pattus, et al.. Individual domains of colicins confer specificity in colicin uptake, in pore-properties and in immunity requirement.. Journal of Molecular Biology, 1991, 217 (3), pp.429-39. ⟨hal-02130283⟩
  • M Frenette, H Bénédetti, A. Bernadac, D. Baty, C Lazdunski. Construction, expression and release of hybrid colicins.. Journal of Molecular Biology, 1991, 217 (3), pp.421-8. ⟨hal-02130287⟩
  • D. Baty, F. Pattus, M. Parker, H. Bénédetti, M. Frenette, et al.. Uptake across the cell envelope and insertion into the inner membrane of ion channel-forming colicins in E coli. Biochimie, 1990, 72 (2-3), pp.123-130. ⟨10.1016/0300-9084(90)90137-6⟩. ⟨hal-02130296⟩
  • C. Lazdunski, H Bénédetti. Insertion and translocation of proteins into and through membranes.. FEBS Letters, 1990, 268 (2), pp.408-14. ⟨hal-02130669⟩
  • H. Bénédetti, M. Frenette, D. Baty, R Lloubès, V. Geli, et al.. Comparison of the Uptake Systems for the Entry of Various BtuB Group Colicins into Escherichia coli. Microbiology, 1989, 135 (12), pp.3413-3420. ⟨10.1099/00221287-135-12-3413⟩. ⟨hal-02130300⟩

Communication dans un congrès16 documents

  • Anthony Champiré, Margaux Sainjon, Abdennour Braka, Samia Aci-Seche, Pascal Bonnet, et al.. Synthesis and preclinical validation of LIMKs inhibitors: Promising drugs for osteosarcoma treatment?. XXVII EFMC International Symposium on Medicinal Chemistry, Sep 2022, NICE, France. ⟨hal-04823073⟩
  • Rayan Berabez, Anthony Champiré, Margaux Sainjon, Abdennour Braka, Samia Aci-Seche, et al.. Synthesis and preclinical validation of LIMKs inhibitors: Promising drugs for osteosarcoma treatment?. SCT 29th Young Research Fellow Meeting, Jul 2022, Nantes, France. ⟨hal-04822252⟩
  • Béatrice Vallée, Christine Mosrin-Huaman, Hélène Bénédetti, Régis Guégan, Bojan Zunar. Life in the bioink: Physiology and energetics of Saccharomyces cerevisiae embedded in polymerized Pluronic F127-DMA, a “smart” thermoresponsive hydrogel. ICY15 meets 30ICYGMB, The spirit of Yeast, Aug 2021, Vienne, virtual, Austria. ⟨hal-03559939⟩
  • Béatrice Vallée, Hélène Bénédetti. Séminaire invité : Signalisation cellulaire et Neurofibromatose. Journées NF, Sep 2021, Orléans, France. ⟨hal-03560050⟩
  • Justine Corret, Sokaina Hammoud, Frédéric Buron, Pierre Daligaux, Christophe Chesné, et al.. Development of a bio­active fluorescent inhibitor probe targeting the Rho kinase ROCK for monitoring inhibition action. FEBS 2021, the 45th FEBS Congress, Jul 2021, Virtual, France. ⟨hal-03668584⟩
  • N Laroui, C Delehedde, C Goncalves, F Godin, Federico Perche, et al.. High Efficiency of Histidylated-based Lipid Formulations for mRNA Transfection of Human Schwann Cells. SFNano 2021, Dec 2021, Angers, France. ⟨hal-03668422⟩
  • H. Bénédetti, Béatrice Vallée, A. Cosson, F. Godin, M. Doudeau. Les LIM kinases : nouvelles cibles thérapeutiques anti-cancer. Journée scientifique du réseau « Cancers hormonaux–dépendants » du Cancéropôle Grand-Ouest, Apr 2019, Nantes, France. ⟨hal-02928496⟩
  • Béatrice Vallée, K. Plé, A. Cosson, M. Doudeau, F. Godin, et al.. Détermination et mise en œuvre d’un modèle in vivo pour tester de nouveaux inhibiteurs originaux des LIM kinases, cibles thérapeutiques émergentes dans le cancer. Cancéropôle Grand Ouest, Colloque du Réseau Molécules marines, métabolisme et cancer, May 2019, Mansigné, France. ⟨hal-02928507⟩
  • M. Bergoug, A. Cosson, D. Casas, M. Doudeau, F. Godin, et al.. Neurofibromin, a new SUMO target involved in neurofibromatosis type 1 disease. 6th LIA Workshop on "Biomarkers and mediators of diseases and new approaches in repair/regenerative therapies, Jun 2019, Varsovie, Poland. ⟨hal-02928511⟩
  • Béatrice Vallée, Karen Plé, A. Cosson, M. Doudeau, F. Godin, et al.. Développement de petites molécules inhibitrices des LIM kinases, nouvelles cibles thérapeutiques pour lutter contre le cancer, les maladies neurologiques et la neurofibromatose. Journée Fédération CBM-ICOA, Jan 2018, Orléans, France. ⟨hal-02928530⟩
  • M. Bergoug, A. Cosson, M. Doudeau, F. Godin, Béatrice Vallée, et al.. Study of the sumoylation of neurofibromin, the protein responsible for neurofibromatosis type 1. Joint Global Neurofibromatosis Conference 2018, Nov 2018, Paris, France. ⟨hal-02928220⟩
  • Béatrice Vallée, S. Routier, A. Cosson, M. Doudeau, F. Godin, et al.. Développement de modulateurs des LIM kinases. Cancéropôle Grand Ouest - 14e colloque du Réseau Produits de la mer en cancérologie - 5e colloque du Réseau Canaux ioniques et cancer, May 2018, Mansigné, France. ⟨hal-02928559⟩
  • Béatrice Vallée, A. Cosson, M. Doudeau, F Godin, A. Braka, et al.. Neurofibromatosis type I: from basic to applied research. 4th LIA Workshop, Jun 2017, Cracovie, Poland. ⟨hal-02928517⟩
  • Béatrice Vallée, Hélène Bénédetti, F. Godin, M. Doudeau. Study of new partners of neurofibromin: an approach to identify novel therapeutic targets for neurofibromatosis type 1. 17th European Neurofibromatosis meeting, Sep 2016, Albano-Terme, Italy. ⟨hal-02928226⟩
  • Wassim Lakhal, Nathalie Boizot, Marie-Claude Lesage Descauses, Odile Rogier, Véronique Laine-Prade, et al.. Both ChIP-SEQ and in planta gene modification demonstrate the involvement of MYB090 and MYB156 in secondary cell wall formation in poplar. INUPRAG-Meeting 2015, Oct 2015, Nancy, France. ⟨hal-01604786⟩
  • J. Tastet, P. Vourc'H, F. Laumonnier, C. Michelle, Anne Duittoz, et al.. Expression des isoformes de LIM Kinase 2 pendant la neurogenèse et la stimulation des neurones. 22. Colloque Biotechnocentre, Oct 2009, Seillac, France. ⟨hal-02753426⟩

Poster32 documents

  • Hélène Bénédetti, Christine Mosrin-Huaman, Mohammed Bergoug, Amandine Serrano, Fabienne Godin, et al.. Deciphering the Molecular Mechanism of Pathogenicity in Destabilized variants of Neurofibromin mutated in its SecPH domain. 2024 Global NF Conference, Jun 2024, Brussels (Belgium), Belgium. ⟨hal-04779581⟩
  • Mohammed Bergoug, Christine Mosrin-Huaman, Amandine Serrano, Fabienne Godin, Michel Doudeau, et al.. Characterization of a new Post Translational Modification of Neurofibromin: atypical structural requirements for its SUMOylation. 2024 Global NF Conference, Jun 2024, Brussels, Belgium. ⟨hal-03679991⟩
  • Mohammed Bergoug, Christine Mosrin-Huaman, Amandine Serrano, Fabienne Godin, Michel Doudeau, et al.. Characterization of a new Post Translational Modification of Neurofibromin: atypical structural requirements for its SUMOylation. 2024 Global NF Conference, Jun 2024, Brussels, Belgium. ⟨hal-04778711⟩
  • Karen Plé, B. Vallée, R. Berabez, A. Champiré, M. Sainjon, et al.. Les LIM kinases, des cibles thérapeutiques prometteuses pour le traitement du glioblastome : de la conception de petites molécules inhibitrices aux tests cellulo. CCCancéropôle Grand Ouest, colloque du réseau Molécules marines, métabolisme et cancer, May 2023, Mansigné, France. ⟨hal-04556346⟩
  • Bojan Zunar, Christine Mosrin-Huaman, Hélène Bénédetti, Régis Guégan, Béatrice Vallée. Stressed by hydrogel? Physiological response of yeast cells embedded in thermoresponsive Pluronic F127: a prerequisite for bioreactor development. FEBS 2021, the 45th FEBS Congress, Jul 2021, Ljubljana, Slovenia. ⟨hal-03679975⟩
  • Bojan Zunar, Christine Mosrin-Huaman, Hélène Bénédetti, Régis Guégan, Béatrice Vallée. Life in the bioink: Physiology and energetics of Saccharomyces cerevisiae embedded in polymerized Pluronic F127-DMA, a “smart” thermoresponsive hydrogel. ICY15 meets 30ICYGMB, The spirit of Yeast, Aug 2021, Vienne, virtual, Austria. ⟨hal-03679966⟩
  • Justine Corret, Sokaina Hammoud, Frédéric Buron, Pierre Daligaux, Christophe Chesné, et al.. Development of a bio­active fluorescent inhibitor probe targeting the Rho kinase ROCK for monitoring inhibition action. FEBS 2021, the 45th FEBS Congress, Jul 2021, Lnubljana, virtual, Slovenia. ⟨hal-03679980⟩
  • Mélissa Thomas, Lauren Blot, Kevin Lesage, Fabienne Godin, Michel Doudeau, et al.. New molecular insights into the crosstalk between Rho/ROCK/LIMK2/cofilin signalling pathway and Nf1. 2021 NF1 virtual conference, Jun 2021, Virtual, France. ⟨hal-03679999⟩
  • Elodie Villalonga, Célina Chalal, Déborah Cassas, Michel Doudeau, Fabienne Godin, et al.. New insights into the regulation of actin cytoskeleton dynamics via the Rho/ROCK/LIMK2/cofilin signalling pathway: a novel mechanism of regulation of cofilin by LIMK2. FEBS 2021, the 45th FEBS Congress, Jul 2021, Ljubljana, virtual, Slovenia. ⟨hal-03680139⟩
  • Christine Mosrin-Huaman, Mohammed Bergoug, Fabienne Godin, Michel Doudeau, Iva Sosic, et al.. Sumoylation of Neurofibromin and its SecPH Domain Plays a Role in Their Functions and Implies Unexpected Structural Requirements. 2021 NF1 virtual conference, Jun 2021, Virtual, France. ⟨hal-03680001⟩
  • N Laroui, C Delehedde, Cristine Gonçalves, F Godin, F Perche, et al.. High Efficiency of Histidylated-based Lipid Formulations for mRNA Transfection of Human Schwann Cells. 10th mRNA Health Conference, Nov 2021, Berlin, Germany. ⟨hal-03668434⟩
  • Christine Mosrin-Huaman, B. Handelaoui, H. Bénédetti, Béatrice Vallée. Yeast biosensors to detect environmental pollutants into effluent waters. ICYGMB XXIX International Congress on Yeast Genetics and Molecular Biology, Aug 2019, Göteborg, Sweden. ⟨hal-02924111⟩
  • M. Bergoug, I. Sošic, M. Doudeau, F. Godin, Béatrice Vallée, et al.. Neurofibromin, a new SUMO target involved in neurofibromatosis type 1 disease. EMBO Workshop "The ubiquitin system: Biology, mechanisms and roles in disease", Sep 2019, Cavtat, Croatia. ⟨hal-02924095⟩
  • Béatrice Vallée, A. Cosson, M. Doudeau, F. Godin, A. Champiré, et al.. LIM kinases, new therapeutic targets to treat cancers, neurological disorders and Neurofibromatosis: development of small molecule inhibitors. FEBS Meeting 2019, Jul 2019, Cracovie, Poland. ⟨hal-02924140⟩
  • H. Bénédetti, M. Bergoug, I. Sošic, M. Doudeau, F. Godin, et al.. Study of the different forms of sumoylation of the neurofibromin SecPH domain. EMBO Workshop "The ubiquitin system: Biology, mechanisms and roles in disease", Sep 2019, Cavtat, Croatia. ⟨hal-02924090⟩
  • H. Bénédetti, Béatrice Vallée, J. Tastet, H. Cubéros, A. Toutain, et al.. Molecular and functional characterization of LIMK2-1, a hominidae-specific isoform of LIMK2 associated with intellectual disability. NeuroFrance 2019, May 2019, Marseille, France. ⟨hal-02924881⟩
  • H. Bénédetti, M. Doudeau, F. Godin, Béatrice Vallée, A. Cosson, et al.. LARP6, a RNA−binding protein involved in translation and stability of collagen mRNA, is a new partner of Neurofibromin: Molecular studies and functional implications. Joint Global Neurofibromatosis Conference 2018, Nov 2018, Paris, France. ⟨hal-02924084⟩
  • Béatrice Vallée, A. Cosson, M. Doudeau, F. Godin, A. Champiré, et al.. Development of small molecule inhibitors of LIM kinases, new therapeutic targets to treat Neurofibromatosis type I. Joint Global Neurofibromatosis Conference 2018, Nov 2018, Paris, France. ⟨hal-02924077⟩
  • Séverine Morisset-Lopez, W. Deraredj Nadim, S. Chaumont−dubel, F. Madouri, L. Cobret, et al.. Neurofibromin 1 promotes constitutive activity of native 5−HT6 receptors expressed in mouse prefrontal cortex. Neurofrance, May 2017, Bordeaux, France. ⟨hal-02973767⟩
  • A. Champiré, A. Braka, B. Vallée, M. Doudeau, F. Godin, et al.. LIM kinases as new therapeutic targets for the treatment of neurofibromatosis type 1. VII International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC) –, Aug 2017, Vienne, Austria. ⟨hal-02904794⟩
  • Béatrice Vallée, A. Cosson, M. Doudeau, F. Godin, Anthony Champiré, et al.. LIM Kinases: new anticancer therapeutic targets. Breast Cancer Symposium, Jun 2017, Nantes, France. ⟨hal-03680148⟩
  • M. Bergoug, A. Cosson, M. Doudeau, F. Godin, Béatrice Vallée, et al.. Study of the sumoylation of neurofibromin, the protein responsible for neurofibromatosis type 1. EMBO Conference "Ubiquitin and SUMO: from molecular mechanisms to system-wide responses, Sep 2017, Cavtat, Croatia. ⟨hal-02924070⟩
  • A. Champiré, A. Braka, Béatrice Vallée, M. Doudeau, F. Godin, et al.. Design, synthesis and biological evaluation of LIMK inhibitors. XXIVe Journées Jeunes Chercheurs (SCT), Feb 2017, Châtenay-Malabry, France. ⟨hal-02904837⟩
  • Béatrice Vallée, Michel Doudeau, F. Godin, H. Cubéros, A. Champiré, et al.. Projet Région LiCorNe: LIMK protein inhibitors, new therapeutic agents for treatment of cognitive disorders associated with type I Neurofibromatosis. Journée Fédération PCV FR2708, Jan 2016, Orléans, France. ⟨hal-02924056⟩
  • W. Deraredj Nadim, S. Chaumont-Dubel, F. Madouri, L. Cobret, M.-L. de Tauzia, et al.. A Physical Interaction between Neurofibromin and Serotonin 5-HT6 Receptor Promotes Receptor Constitutive Activity. 5th annual meeting of the GDR 3545 RCPG-PhysioMed 2016, Nov 2016, Tours, France. ⟨hal-02973912⟩
  • Annabelle Dejardin, Wassim Lakhal, Nathalie Boizot, Marie-Claude Lesage Descauses, Odile Rogier, et al.. Unraveling the function of MYB090 and MYB156 in secondary cell wall formation in poplar using both ChIP-SEQ and in planta gene modification approach. XIV Cell Wall Meeting, Jun 2016, Chania, Grèce. , 2016, XIV Cell Wall Meeting. Programme and Book of Abstracts. ⟨hal-02740921⟩
  • Béatrice Vallée, Michel Doudeau, Fabienne Godin, Anthony Champiré, Karen Plé, et al.. LIM kinases: new therapeutic targets to treat Neurofibromatosis type I. The 7th EMBO meeting, Sep 2016, Mannheim, Germany. . ⟨hal-02453490⟩
  • Hélène Bénédetti, Fabienne Godin, Michel Doudeau, Béatrice Vallée, Marie-Ludivine De Tauzia, et al.. LINGO-1, a protein involved in various neurodevelopmental processes, interacts with neurofibromin (Nf1), the protein responsible for neurofibromatosis type I: molecular studies and functional implications. 10 th FENS (Forum of Neuroscience), Jul 2016, Copenhague, Denmark. ⟨hal-02453487⟩
  • Béatrice Vallée, Hélène Cuberos, Michel Doudeau, Fabienne Godin, Patrick Vourc’h, et al.. The three isoforms of human LIMK2 regulate actin cytoskeleton remodeling via different pathways. EMBL Symposium, Actin in action: From Molecules to Cellular Functions, Sep 2016, Heidelberg, Germany. . ⟨hal-02453489⟩
  • Béatrice Vallée, Hélène Cuberos, Julie Tastet, Michel Doudeau, Fabienne Godin, et al.. LIMK2-1, a new primate-specific isoform of LIMK2, is associated with intellectual disability. 10 th FENS (Forum of Neurosciences), Jul 2016, Copenhague, Denmark. . ⟨hal-02453486⟩
  • A. Champiré, A. Braka, Béatrice Vallée, M. Doudeau, F. Godin, et al.. Conception, synthèse et évaluation biologique d’inhibiteurs de LIM kinases. 29e colloque de Biotechnocentre, Oct 2016, Seillac, France. ⟨hal-02904847⟩
  • J. Tastet, P. Vourc'H, F. Laumonnier, C. Michelle, Anne Duittoz, et al.. LIMK2 (LIM kinase2) isoforms are differentially expressed during neuronal differentiation. 7. FENS Forum of European Neuroscience, Jul 2010, Amsterdam, Netherlands. n.p., 2010. ⟨hal-02818145⟩

Chapitre d'ouvrage7 documents

  • Emmanuelle Bouveret, Claude Lazdunski, Hélène Bénédetti. The Tol/PAL and TonB systems : two envelope-spanning protein complexes involved in colicin import in E. coli.. Molecular Dynamics of Biomembranes, Springer Berlin Heidelberg, pp.59-69, 1996. ⟨hal-02130680⟩
  • H. Bénédetti, V. Geli. Colicin transport, channel formation and inhibition. Handbook of Biological Physics, pp.665-691, 1996. ⟨hal-02130677⟩
  • Vincent Géli, Hélène Bénédetti. Insertion of Proteins into Membranes A Survey. Membrane biogenesis, pp.21-69, 1994, Subcellular Biochemistry, 978-1-4613-6018-6. ⟨hal-02130265⟩
  • L. Letellier, C. Lazdunski, H. Bénédetti, J. Bourdineaud, P. Boulanger. In Vivo Properties of Colicin A: Channel Activity and Translocation. Bacteriocins, Microcins and Lantibiotics, Springer Berlin Heidelberg, pp.119-125, 1992. ⟨hal-02130671⟩
  • C. Lazdunski, D. Baty, V. Geli, R. Lloubes, H. Bénédetti, et al.. Molecular Mechanism of Action of Pore-Forming Colicins and of their Immunity Proteins. Membrane Proteins: Structures, Interactions and Models, pp.413-425, 1992. ⟨hal-02130675⟩
  • Hélène Bénédetti, Lucienne Letellier, Roland Lloubes, Vincent Géli, Daniel Baty, et al.. Import of Colicins into Escherichia Coli. Dynamics of Membrane Assembly, 63, Springer Berlin Heidelberg, pp.315-332, 1992. ⟨hal-02130670⟩
  • Hélène Bénédetti, Lucienne Letellier, Roland Lloubes, Vincent Géli, Daniel Baty, et al.. Study of the Import Mechanisms of Colicins Through Protein Engineering and K+ Efflux Kinetics. Bacteriocins, Microcins and Lantibiotics, Springer Berlin Heidelberg, pp.215-223, 1992. ⟨hal-02130674⟩

Brevet3 documents

  • Sylvain Routier, Hélène Bénédetti, Béatrice Vallée, Pascal Bonnet, Karen Plé, et al.. 4-(7H-Pyrrolo[2,3-D]pyrimidin-4-yl)-3,6-dihydropyridine-(2H)-carboxamide derivatives as Limk and/or Rock kinases inhibitors for use in the treatment of cancer. France, Patent n° : WO2021239727 A1. AMV. 2021. ⟨hal-03555349⟩
  • Sylvain Routier, Hélène Bénédetti, Frederic Buron, Marie-Aude Hiebel, Thibault Saurat, et al.. TRISUBSTITUTED PYRIDO[2,3-D]PYRIMIDINES, METHODS FOR PREPARING SAME AND THERAPEUTIC USES THEREOF. France, Patent n° : WO2014027081. 2014. ⟨hal-02131560⟩
  • Séverine Morisset-Lopez, Hélène Bénédetti. Tools for the identification od LINGO-1, LINGO-2, LINGO-3 and LINGO-4, ligands, and uses thereof. France, Patent n° : WO2011121257. BCT. 2011. ⟨hal-02130935⟩

Pré-publication, Document de travail1 document

  • Mohammed Bergoug, Christine Mosrin, Fabienne Godin, Michel Doudeau, Iva Sosic, et al.. Noncanonical structural requirements of neurofibromin SUMOylation reveal a folding-deficiency of several pathogenic mutants. 2022. ⟨hal-03668582⟩

Documents récupérés de l'archive ouverte HAL logo

BEAUFOUR Martine

email : martine.beaufour[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.78.57 ou 54.57

Lecturer within the thematic group “Functional Mass Spectrometry in Metastasis“

 


22 documents

Article dans une revue12 documents

  • Martine Beaufour, David Ginguené, Rémy Le Meur, Bertrand Castaing, Martine Cadène. Liquid Native MALDI Mass Spectrometry for the Detection of Protein-Protein Complexes. Journal of The American Society for Mass Spectrometry, 2018, 29 (10), pp.1981-1994. ⟨10.1007/s13361-018-2015-x⟩. ⟨hal-01965971⟩
  • Caroline Teyssier, Stéphane Maury, Martine Beaufour, Cécile Grondin, Alain Delaunay, et al.. In search of markers for somatic embryo maturation in hybrid larch ( Larix × eurolepis ): global DNA methylation and proteomic analyses. Physiologia Plantarum, 2014, 150 (2), pp.271-291. ⟨10.1111/ppl.12081⟩. ⟨hal-02087600⟩
  • Alexandre Morel, Jean-François Trontin, Françoise Corbineau, Anne-Marie Lomenech, Martine Beaufour, et al.. Cotyledonary somatic embryos of Pinus pinaster Ait. most closely resemble fresh, maturing cotyledonary zygotic embryos: biological, carbohydrate and proteomic analyses.. Planta, 2014, 240 (5), pp.1075-1095. ⟨10.1007/s00425-014-2125-z⟩. ⟨hal-01179478⟩
  • Alexandre Morel, Caroline Teyssier, Jean-François Trontin, Kateřina Eliášová, Bedřich Pešek, et al.. Early molecular events involved in Pinus pinaster Ait. somatic embryo development under reduced water availability: transcriptomic and proteomic analyses. Physiologia Plantarum, 2014, 152 (1), pp.184-201. ⟨10.1111/ppl.12158⟩. ⟨hal-01179486⟩
  • Martine Beaufour, Fabienne Godin, Béatrice Vallée, Martine Cadene, Hélène Bénédetti. Interaction Proteomics Suggests a New Role for the Tfs1 Protein in Yeast.. Journal of Proteome Research, 2012, 11 (6), pp.3211-3218. ⟨10.1021/pr201239t⟩. ⟨hal-00721771⟩
  • M. Beaufour, Philippe Morin, J.P. Ribet, J.C. Maurizot. HPLC quantitation of the four stereoisomers of benzoxathiepin derivatives with cellulose phenyl type chiral stationary phase and circular dichroism detection. Journal of Pharmaceutical and Biomedical Analysis, 2006, 41 (2), pp.544-548. ⟨10.1016/j.jpba.2005.11.034⟩. ⟨hal-00088834⟩
  • Martine Beaufour, Philippe Morin, Jean-Paul Ribet. Chiral separation of the four stereoisomers of a novel antianginal agent using a dual cyclodextrin system in capillary electrophoresis.. Journal of Separation Science, 2005, 28 (6), pp.529-33. ⟨10.1002/jssc.200400097⟩. ⟨hal-02087618⟩
  • M. Beaufour, B. Merelli, L. Menguy, J.-C. Cherton. Determination of the enantiomeric composition of chiral delta-2-oxazolines-1,3 by 1H and 19F NMR spectroscopy using chiral solvating agents. Chirality, 2003, 15 (5), pp.382-390. ⟨10.1002/chir.10225⟩. ⟨hal-02087633⟩
  • J.-C. Cherton, M. Beaufour, L. Menguy, B. Merelli. DETERMINATION OF THE ENANTIOMERIC COMPOSITION OF CHIRAL Δ-2-OXAZOLINES-1,3 BY 1 H AND 19 F NMR SPECTROSCOPY USING CHIRAL LANTHANIDE-SHIFT REAGENTS. Spectroscopy Letters : An International Journal for Rapid Communication, 2002, 35 (3), pp.415-437. ⟨10.1081/SL-120005675⟩. ⟨hal-02149583⟩
  • J.-C Cherton, S Hamm, J.-C Hallé, L Menguy, M. Beaufour. Potential proinsecticides of fluorinated carboxylic acids and β-ethanolamines: IV. Evaluation of the Δ2-oxazoline-1,3 structure by 19F NMR monitoring of the in vitro metabolism in locust tissues. Journal of Fluorine Chemistry, 2001, 107 (2), pp.387-395. ⟨10.1016/S0022-1139(00)00382-1⟩. ⟨hal-02149605⟩
  • François Terrier, Martine Beaufour, Jean-Claude Halle, Jean-Claude Cherton, Erwin Buncel. A remarkably facile oxygen transfer in a nitrobenzofuroxan structure activated through σ-complex formation. Tetrahedron Letters, 2001, 42 (27), pp.4499-4501. ⟨10.1016/S0040-4039(01)00774-2⟩. ⟨hal-02149596⟩
  • M. Beaufour, J.C Cherton, A Carlin-Sinclair, S Hamm. Delta(2)-oxazolines-1,3 and N-acylaziridines as potential proinsecticides of carboxylic acids. V. Direct thin-layer chromatography monitoring of the metabolism in locust tissues.. Journal of Chromatography B Biomedical Sciences and Applications, 2001, 761 (1), pp.35-45. ⟨10.1016/S0378-4347(01)00295-X⟩. ⟨hal-02149591⟩

Communication dans un congrès3 documents

  • Edison F Zhamungui, Cedric Orelle, Jean-Michel Jault, Joekeem del Rosario Arizala, Sébastien F. Poget, et al.. Structural biology of membrane proteins and their complexes using Native Liquid MALDI (NALIM) Mass Spectrometry (MS). Analytics 2022, Sep 2022, Nantes, France. ⟨hal-03845786⟩
  • Alexandre Morel, Caroline Teyssier, Jean-François Trontin, Kateřina Eliášová, Pešek Bedřichc, et al.. Multi-scale analysis of early molecular events during Pinus pinaster Ait. somatic embryo development under reduced water availability. 3. International Conference of the IUFRO Working Party 2.09.02: Somatic Embryogenesis and Other Vegetative Propagation Technologies, International Union of Forest Research Organisations (IUFRO). Vienne, AUT., Sep 2014, Vitoria-Gasteiz, Spain. 220 p. ⟨hal-02740937⟩
  • Caroline Teyssier, Alexandre Morel, Jean-François Trontin, Françoise Corbineau, Anne-Marie Lomenech, et al.. Did cotyledonary somatic embryos of Pinus pinaster Ait. similar to cotyledonary zygotic embryos ?. International Conference of the IUFRO Working Party 2.09.02: Somatic Embryogenesis and Other Vegetative Propagation Technologies, Sep 2014, Vitoria-Gasteiz, Spain. ⟨hal-03809831⟩

Poster7 documents

  • Lucija Mance, Nicolas Bigot, Edison Zhamungui Sánchez, Franck Coste, Natalia Martín-González, et al.. Studies of BTB domain polymerisation through integrative structural biology. FRISBI User Meeting 2024, CNRS campus Gif-sur-Yvette, Jan 2024, Gif sur Yvette, France. ⟨hal-04778726⟩
  • Edison F Zhamungui, Cedric Orelle, Jean-Michel Jault, Joekeem del Rosario Arizala, Sébastien F. Poget, et al.. NALIM: NATIVE LIQUID MALDI MASS SPECTROMETRY AS A NEW STRUCTURAL METHOD TO DIRECTLY CHARACTERIZE MEMBRANE PROTEIN COMPLEXES. IMSC (International Mass Spectrometry Conference), Aug 2022, Maastricht, Netherlands. ⟨hal-03863124⟩
  • Edison F Zhamungui, Martine Beaufour, Martine Cadene. Search for a high-mass calibrant for NALIM (Native Liquid MALDI MS): the case of mouse IgA. Journées Françaises de Spectrométrie de Masse, Jun 2021, Virtual, France. , 2020, ⟨10.7554/elife.56098⟩. ⟨hal-03404684⟩
  • Caroline Teyssier, Alexandre Morel, Jean-François Trontin, Francoise Corbineau, Anne-Marie Lomenech, et al.. Are cotyledonary somatic embryos of Pinus pinaster Ait. equivalent to the zygotic counterpart ?. 3. International Conference of the IUFRO Working Party 2.09.02: Somatic Embryogenesis and Other Vegetative Propagation Technologies, Sep 2014, Vitoria-Gasteiz, Spain. 2014, 3rd International Conference of the IUFRO Working Party 2.09.02: Somatic Embryogenesis and Other Vegetative Propagation Technologies. Book of Abstracts. ⟨hal-01269493⟩
  • Marie-Anne Lelu-Walter, Alexandre A. Morel, Caroline Teyssier, Martine Beaufour, Isabelle Reymond, et al.. Somatic embryo development in maritime pine (Pinus pinaster): a 2-DE proteomic analysis. 4. UPSC-INRA (UPRA) Bilateral Meeting, Mar 2012, Umea, Sweden. 2012, 4th UPSC-INRA (UPRA) bilateral meeting. Meeting book with abstracts. ⟨hal-02746152⟩
  • Alexandre Morel, Caroline Teyssier, Martine Beaufour, Isabelle Reymond, Claire Le Mette, et al.. Somatic embryo maturation in maritime pine (Pinus pinaster) : contribution of a 2-DE proteomic analysis for a better understanding. 2. International Conference of the IUFRO Working Party 2.09.02, "Somatic Embryogenesis and Other Vegetative Propagation Technologies", Jun 2012, Brno, Czech Republic. 2012, Integrating vegetative propagation, biotechnologies and genetic improvement for tree production and sustainable forest management. Proceedings. ⟨hal-01268054⟩
  • Martine Beaufour, Alexandre A. Morel, Caroline Teyssier, Luc Harvenght, Jean-François Trontin, et al.. Differential proteomics for the evaluation of the effect of environmental culture conditions on the protein expression of somatic embryos from Pinus pinaster. SMAP 2011 - 28èmes Journées Françaises de Spectrométrie de Masse, Sep 2011, Avignon, France. 2011, Spectroscopie de Masse et Analyse Protéomique. ⟨hal-02746570⟩

Documents récupérés de l'archive ouverte HAL logo

AUCAGNE Vincent

email : vincent.aucagne[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.55.77

Research director, Leader of the team “Synthetic protein and bioorthogonal chemistry”


173 documents

Article dans une revue71 documents

  • Hugo Terrasson, Karen Gaget, Garance Lapetoule, Isabelle Rahioui, François Renoz, et al.. Strong impact of orally administered BCR4 defensin on aphid survival, embryo development, and symbiotic cells in three Acyrthosiphon pisum parthenogenetic lines. Journal of Pest Science, 2025, 98 (3), pp.1599-1612. ⟨10.1007/s10340-025-01923-0⟩. ⟨hal-05127596⟩
  • Chloe Beaudou, Louise Sionneau, Didier Lomet, Vincent Robert, P Jarrier-Gaillard, et al.. The kisspeptin analog C6 reverses reproductive dysfunction in a mouse model of hyperprolactinemia. Reproduction [Cambridge], 2025, 169 (4), pp.e250036. ⟨10.1530/REP-25-0036⟩. ⟨hal-05135772⟩
  • Kang Zhu, Chatrin Chatrin, Marcin J Suskiewicz, Vincent Aucagne, Benjamin Foster, et al.. Ubiquitylation of nucleic acids by DELTEX ubiquitin E3 ligase DTX3L. EMBO Reports, 2024, 25 (10), pp.4172-4189. ⟨10.1038/s44319-024-00235-1⟩. ⟨hal-04739061⟩
  • Ana Novak, Florian Kersaudy, Sylvie Berger, Séverine Morisset-Lopez, François Lefoulon, et al.. An efficient site-selective, dual bioconjugation approach exploiting N-terminal cysteines as minimalistic handles to engineer tailored anti-HER2 affibody conjugates. European Journal of Medicinal Chemistry, 2023, 260, pp.115747. ⟨10.1016/j.ejmech.2023.115747⟩. ⟨hal-04222710⟩
  • Karine Loth, Nicolas Parisot, Françoise Paquet, Hugo Terrasson, Catherine Sivignon, et al.. Aphid BCR4 Structure and Activity Uncover a New Defensin Peptide Superfamily. International Journal of Molecular Sciences, 2022, 23 (20), pp.12480. ⟨10.3390/ijms232012480⟩. ⟨hal-03862651⟩
  • Céline Landon, Yanyu Zhu, Mainak Mustafi, Jean-Baptiste Madinier, Dominique Lelièvre, et al.. Real-Time Fluorescence Microscopy on Living E. coli Sheds New Light on the Antibacterial Effects of the King Penguin beta-Defensin AvBD103b. International Journal of Molecular Sciences, 2022, This article belongs to the Special Issue Antimicrobial Peptides: Structure and Mechanism of Biological Activity, 23 (2057), pp.2057. ⟨10.3390/ijms23042057⟩. ⟨hal-03860107⟩
  • Noémie de San Nicolas, Aromal Asokan, Rafael D Rosa, Sébastien N Voisin, Marie-Agnès Travers, et al.. Functional Diversification of Oyster Big Defensins Generates Antimicrobial Specificity and Synergy against Members of the Microbiota. Marine drugs, 2022, 20 (12), pp.745. ⟨10.3390/md20120745⟩. ⟨hal-04246173⟩
  • Diana Fanelli, Massimiliano Beltramo, Giuseppe Conte, Benedetta Cerretini, Didier Lomet, et al.. The Kisspeptin analogue C6 induces ovulation in jennies. Theriogenology, 2022, 189, pp.107-112. ⟨10.1016/j.theriogenology.2022.06.014⟩. ⟨hal-03746194⟩
  • Kang Zhu, Marcin Suskiewicz, Andrea Hloušek-Kasun, Hervé Meudal, Andreja Mikoč, et al.. DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on protein substrates. Science Advances , 2022, 8 (40), ⟨10.1126/sciadv.add4253⟩. ⟨hal-03862525⟩
  • Flavie Derouin Tochon, Didier Lomet, Vincent Robert, Fabrice Reigner, Philippe Barrière, et al.. Treating mares with the long-acting kisspeptin analog C6 increases circulating gonadotropins but does not trigger ovulation. Agriculture, 2022, 12 (11), pp.1846. ⟨10.3390/agriculture12111846⟩. ⟨hal-03862471⟩
  • Ahlame Saidi, Mylène Wartenberg, J.B Madinier, Guy Ilango, Seda Seren, et al.. Monitoring Human Neutrophil Activation by a Proteinase 3 Near-Infrared Fluorescence Substrate-Based Probe. Bioconjugate Chemistry, 2021, 32 (8), pp.1782-1790. ⟨10.1021/acs.bioconjchem.1c00267⟩. ⟨hal-03525228⟩
  • Sophie Laine, Jean-François Morfin, Mathieu Galibert, Vincent Aucagne, Celia ́ Bonnet, et al.. Lanthanide DO3A-Complexes Bearing Peptide Substrates: The Effect of Peptidic Side Chains on Metal Coordination and Relaxivity. Molecules, 2021, 26 (8), pp.2176. ⟨10.3390/molecules26082176⟩. ⟨hal-03437152⟩
  • Skander Abboud, Mehdi Amoura, Jean-Baptiste Madinier, Brigitte Renoux, Sébastien Papot, et al.. Enzyme‐Cleavable Linkers for Protein Chemical Synthesis through Solid‐Phase Ligations. Angewandte Chemie International Edition, 2021, 60 (34), pp.18612-18618. ⟨10.1002/anie.202103768⟩. ⟨hal-05019646⟩
  • Skander A Abboud, Mehdi Amoura, J.B Madinier, Brigitte Renoux, Sébastien Papot, et al.. Enzyme‐Cleavable Linkers for Protein Chemical Synthesis through Solid‐Phase Ligations. Angewandte Chemie International Edition, 2021, 60 (34), pp.18612-18618. ⟨10.1002/anie.202103768⟩. ⟨hal-03335485⟩
  • Vincent Aucagne, Fabienne Burlina, Oleg Melnyk, Vladimir Torbeev. Des protéines de synthèse taillées sur mesure pour investiguer le vivant. L'Actualité Chimique, 2021, 468, pp.26-28. ⟨hal-02959387⟩
  • Skander A Abboud, Hadji H., Michel Doudeau, Hélène Bénédetti, Vincent Aucagne. A straightforward methodology to overcome solubility challenges for N-terminal cysteinyl peptide segments used in native chemical ligation. Chemical Science, 2021, 12, pp.3194 - 3201. ⟨10.1039/d0sc06001a⟩. ⟨hal-03447239⟩
  • Nicolas Guyot, Herve Meudal, Sascha Trapp, Sophie Iochmann, Anne Silvestre, et al.. Structure, function, and evolution of Gga -AvBD11, the archetype of the structural avian-double-β-defensin family. Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (1), pp.337-345. ⟨10.1073/pnas.1912941117⟩. ⟨hal-02522250⟩
  • Charlotte Rieux, Stéphane Goffinont, Franck Coste, Zahira Tber, Julien Cros, et al.. Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights. International Journal of Molecular Sciences, 2020, 21 (6), pp.2058. ⟨10.3390/ijms21062058⟩. ⟨hal-03082414⟩
  • Skander A. Abboud, Vincent Aucagne. An optimized protocol for the synthesis of N -2-hydroxybenzyl-cysteine peptide crypto-thioesters. Organic & Biomolecular Chemistry, 2020, 18 (40), pp.8199-8208. ⟨10.1039/d0ob01737j⟩. ⟨hal-02975540⟩
  • Mylène Wartenberg, Ahlame Saidi, Mathieu Galibert, Alix Joulin-Giet, Julien Burlaud-Gaillard, et al.. Imaging of extracellular cathepsin S activity by a selective near infrared fluorescence substrate-based probe. Biochimie, 2019, 166, pp.84-93. ⟨10.1016/j.biochi.2019.03.013⟩. ⟨hal-02088627⟩
  • Caroline Decourt, Vincent Robert, Didier Lomet, Karine Anger, Marion Georgelin, et al.. The kisspeptin analog C6 is a possible alternative to PMSG (pregnant mare serum gonadotropin) for triggering synchronized and fertile ovulations in the Alpine goat. PLoS ONE, 2019, 14 (3), pp.e0214424. ⟨10.1371/journal.pone.0214424⟩. ⟨hal-02088631⟩
  • Julien Diharce, Mickaël Cueto, Massimiliano Beltramo, Vincent Aucagne, Pascal Bonnet. In silico peptide ligation: Iterative Residue Docking and Linking as a new approach to predict protein-peptide interactions. Molecules, 2019, 24 (7), pp.1-14. ⟨10.3390/molecules24071351⟩. ⟨hal-03525312⟩
  • P.A. Parker, E.A. Coffman, K.G. Pohler, J.A. Daniel, V. Aucagne, et al.. Acute and subacute effects of a synthetic kisspeptin analog, C6, on serum concentrations of luteinizing hormone, follicle stimulating hormone, and testosterone in prepubertal bull calves. Theriogenology, 2019, 130, pp.111-119. ⟨10.1016/j.theriogenology.2019.03.002⟩. ⟨hal-02088608⟩
  • Karine Loth, Agnès Vergnes, Cairé Barreto, Sébastien N Voisin, Hervé Meudal, et al.. The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets. mBio, 2019, 10 (5), pii: e01821-19. ⟨10.1128/mBio.01821-19⟩. ⟨hal-02328576⟩
  • Monika Cieslikiewicz-Bouet, Svetlana Eliseeva, Vincent Aucagne, A.F. Delmas, Isabelle Gillaizeau, et al.. Near-infrared emitting lanthanide(III) complexes as prototypes of optical imaging agents with peptide targeting ability: a methodological approach. RSC Advances, 2019, 9 (3), pp.1747-1751. ⟨10.1039/c8ra09419e⟩. ⟨hal-02064990⟩
  • Mylène Wartenberg, Ahlame Saidi, Mathieu Galibert, Alix Joulin-Giet, Julien Burlaud-Gaillard, et al.. Imaging of extracellular cathepsin S activity by a selective near infrared fluorescence substrate-based probe. Biochimie, 2019, 166, pp.84-93. ⟨10.1016/j.biochi.2019.03.013⟩. ⟨hal-03677252⟩
  • Matthieu Galibert, Mylène Wartenberg, Fabien Lecaille, Ahlame Saidi, Sylvie Mavel, et al.. Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S. European Journal of Medicinal Chemistry, 2018, 144, pp.201 - 210. ⟨10.1016/j.ejmech.2017.12.012⟩. ⟨hal-01702303⟩
  • David Montoir, Mehdi Amora, Zine El Abidine Aabasa, Thimmalapura Marulappa Vishwanatha, Expédite Yen-Pon, et al.. Synthesis of aryl-thioglycopeptides through chemoselective Pd-Mediated conjugation. Chemical Science, 2018, 9 (46), pp.8753-8759. ⟨10.1039/C8SC02370K⟩. ⟨hal-02622102⟩
  • Matthieu Galibert, Mylène Wartenberg, Fabien Lecaille, Ahlame Saidi, Sylvie Mavel, et al.. Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S. European Journal of Medicinal Chemistry, 2018, 144, pp.201-210. ⟨10.1016/j.ejmech.2017.12.012⟩. ⟨hal-03677245⟩
  • Victor Terrier, Agnès F. Delmas, Vincent Aucagne. Efficient synthesis of cysteine-rich cyclic peptides through intramolecular native chemical ligation of N-Hnb-Cys peptide crypto-thioesters. Organic & Biomolecular Chemistry, 2017, 15 (2), pp.316 - 319. ⟨10.1039/c6ob02546c⟩. ⟨hal-01618781⟩
  • Guillaume Martinez, Jean-Pascal Hograindleur, Sébastien Voisin, Roland Abi Nahed, Tarek M. Abd El Aziz, et al.. Spermaurin, an La1-like peptide from the venom of the scorpion Scorpio maurus palmatus , improves sperm motility and fertilization in different mammalian species. Molecular Human Reproduction, 2017, 23 (2), pp.116-131. ⟨10.1093/molehr/gaw075⟩. ⟨hal-01618630⟩
  • Audrey Gambade, Sami Zreika, Maxime Guéguinou, Igor Chourpa, Gaëlle Fromont, et al.. Activation of TRPV2 and BKCa channels by the LL-37 enantiomers stimulates calcium entry and migration of cancer cells.. Oncotarget, 2016, 7 (17), pp.23785-23800. ⟨10.18632/oncotarget.8122⟩. ⟨hal-01387061⟩
  • Karine Loth, Soha Abou Ibrahim Alami, Chahrazed Habès, Solène Garrido, Vincent Aucagne, et al.. Complete 1H, 15N and 13C assignment of trappin-2 and 1H assignment of its two domains, elafin and cementoin. Biomolecular NMR Assignments, 2016, 10 (1), pp.223 - 226. ⟨10.1007/s12104-016-9671-1⟩. ⟨hal-01407495⟩
  • Michael T. Jacobsen, Mark E. Petersen, Xiang Ye, Mathieu Galibert, George H. Lorimer, et al.. A Helping Hand to Overcome Solubility Challenges in Chemical Protein Synthesis. Journal of the American Chemical Society, 2016, 138 (36), pp.11775 - 11782. ⟨10.1021/jacs.6b05719⟩. ⟨hal-01407028⟩
  • Caroline Decourt, Vincent Robert, Karine Anger, Mathieu Galibert, Jean-Baptiste Madinier, et al.. A synthetic kisspeptin analog that triggers ovulation and advances puberty. Scientific Reports, 2016, 6 (1), pp.26908. ⟨10.1038/srep26908⟩. ⟨hal-01406943⟩
  • Victor P. Terrier, Hélène Adihou, Mathieu Arnould, Agnès F. Delmas, Vincent Aucagne. A straightforward method for automated Fmoc-based synthesis of bio-inspired peptide crypto-thioesters. Chemical Science, 2016, 7 (1), pp.339 - 345. ⟨10.1039/C5SC02630J⟩. ⟨hal-01407765⟩
  • Dominique Lelièvre, Victor P. Terrier, Agnès F. Delmas, Vincent Aucagne. Native Chemical Ligation Strategy to Overcome Side Reactions during Fmoc-Based Synthesis of C-Terminal Cysteine-Containing Peptides. Organic Letters, 2016, 18 (5), pp.920 - 923. ⟨10.1021/acs.orglett.5b03612⟩. ⟨hal-01407492⟩
  • Mathieu Galibert, Véronique Piller, Friedrich Piller, Vincent Aucagne, Agnès F. Delmas. Combining triazole ligation and enzymatic glycosylation on solid phase simplifies the synthesis of very long glycoprotein analogues. Chemical Science, 2015, 6 (6), pp.3617-3623. ⟨10.1039/C5SC00773A⟩. ⟨hal-01178852⟩
  • Massimiliano Beltramo, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, Philippe Marceau, et al.. Rational Design of Triazololipopeptides Analogs of Kisspeptin Inducing a Long-Lasting Increase of Gonadotropins. Journal of Medicinal Chemistry, 2015, 58 (8), pp.3459-3470. ⟨10.1021/jm5019675⟩. ⟨hal-01170460⟩
  • Romain Barat, Thibaut Legigan, I. Tranoy-Opalinski, Brigitte Renoux, Elodie Peraudeau, et al.. A mechanically interlocked molecular system programmed for the delivery of an anticancer drug. Chemical Science, 2015, 6 (4), pp.2608-2613. ⟨10.1039/c5sc00648a⟩. ⟨hal-03127729⟩
  • Isidore E. Decostaire, Dominique Lelièvre, Vincent Aucagne, Agnès F. Delmas. Solid phase oxime ligations for the iterative synthesis of polypeptide conjugates. Organic & Biomolecular Chemistry, 2014, 12 (29), pp.5536-5543. ⟨10.1039/c4ob00760c⟩. ⟨hal-01178857⟩
  • Fanny Meindre, Dominique Lelièvre, Karine Loth, Oriane Mith, Vincent Aucagne, et al.. The nuclear magnetic resonance solution structure of the synthetic AhPDF1.1b plant defensin evidences the structural feature within the γ-motif. Biochemistry, 2014, 53 (49), pp.7745-54. ⟨10.1021/bi501285k⟩. ⟨hal-01118914⟩
  • Laurent Raibaut, Hélène Adihou, Rémi Desmet, Agnès F. Delmas, Vincent Aucagne, et al.. Highly efficient solid phase synthesis of large polypeptides by iterative ligations of bis(2-sulfanylethyl)amido (SEA) peptide segments. Chemical Science, 2013, 4, pp.4061-4066. ⟨10.1039/c3sc51824h⟩. ⟨hal-00944814v2⟩
  • Vincent Aucagne, Ibai E Valverde, Philippe Marceau, Mathieu Galibert, Nabil Dendane, et al.. Towards the simplification of protein synthesis: iterative solid-supported ligations with concomitant purifications.. Angewandte Chemie International Edition, 2012, 51 (45), pp.11320-4. ⟨10.1002/anie.201206428⟩. ⟨hal-00748170⟩
  • Antony Fernandes, Aurélien Viterisi, Vincent Aucagne, David A Leigh, Sébastien Papot. Second generation specific-enzyme-activated rotaxane propeptides.. Chemical Communications, 2012, 48 (15), pp.2083-5. ⟨10.1039/c2cc17458h⟩. ⟨hal-00678757⟩
  • Chrystelle Derache, Hervé Meudal, Vincent Aucagne, Kevin J Mark, Martine Cadène, et al.. Initial insights into structure-activity relationships of avian defensins.. Journal of Biological Chemistry, 2012, 287 (10), pp.7746-55. ⟨10.1074/jbc.M111.312108⟩. ⟨hal-00721842⟩
  • Ibai E Valverde, Fabien Lecaille, Gilles Lalmanach, Vincent Aucagne, Agnès F Delmas. Synthesis of a biologically active triazole-containing analogue of cystatin A through successive peptidomimetic alkyne-azide ligations.. Angewandte Chemie International Edition, 2012, 51 (3), pp.718-22. ⟨10.1002/anie.201107222⟩. ⟨hal-00726293⟩
  • Christelle Gaulier, Audrey Hospital, Bertrand Legeret, Delmas A.F., Vincent Aucagne, et al.. A water soluble Cu-I-NHC for CuAAC ligation of unprotected peptides under open air conditions.. Chemical Communications, 2012, 48, pp.4005-4007. ⟨hal-00711780⟩
  • Andrea Altieri, Vincent Aucagne, Romen Carrillo, Guy Clarkson, Daniel d'Souza, et al.. Sulfur-containing amide-based [2]rotaxanes and molecular shuttles. Chemical Science, 2011, 2 (10), pp.1922. ⟨10.1039/C1SC00335F⟩. ⟨hal-02088663⟩
  • Anthony Fernandes, Aurélien Viterisi, Frédéric Coutrot, Stéphanie Potok, David A. Leigh, et al.. Rotaxane-based propeptides: protection and enzymatic release of a bioactive pentapeptide.. Angewandte Chemie International Edition, 2009, 48 (35), pp.6443-7. ⟨10.1002/anie.200903215⟩. ⟨hal-00467015⟩
  • Chrystelle Derache, Valérie Labas, Vincent Aucagne, Hervé Meudal, Céline Landon, et al.. Primary Structure and Antibacterial Activity of Chicken Bone Marrow-Derived beta-Defensins. Antimicrobial Agents and Chemotherapy, 2009, 53 (11), pp.4647-4655. ⟨10.1128/AAC.00301-09⟩. ⟨hal-00522326⟩
  • Ibai E. Valverde, Agnès F. Delmas, Vincent Aucagne. Click a la carte: robust semi-orthogonal alkyne protecting groups for multiple successive azide/alkyne cycloadditions. Tetrahedron, 2009, 65 (36), pp.7597-7602. ⟨10.1016/j.tet.2009.06.093⟩. ⟨hal-00525398⟩
  • Dominique Lelièvre, P. Barta, Vincent Aucagne, A.F. Delmas. Preparation of peptide thioesters using Fmoc strategy through hydroxyl side chain anchoring. Tetrahedron Letters, 2008, 49 (25), pp.4016-4019. ⟨10.1016/j.tetlet.2008.04.087⟩. ⟨hal-00518141⟩
  • Vincent Aucagne, A. Tatibouët, Patrick Rollin. Thermodynamics versus kinetics in hetero-Michael cyclizations: a highly stereoselective approach to access both epimers of a C-D-mannopyranoside. Tetrahedron Letters, 2008, 49, pp.4750-4753. ⟨10.1016/j.tetlet.2008.05.117⟩. ⟨hal-00512453⟩
  • Vincent Aucagne, J. Berna, Jd Crowley, Sm Goldup, Kd Haenni, et al.. Catalytic "Active-Metal" template synthesis of [2]rotaxanes, [3]rotaxanes, and molecular shuttles, and some observations on the mechanism of the Cu(I)-catalyzed azide-alkyne 1,3-cycloaddition. Journal of the American Chemical Society, 2007, 129, pp.11950-11963. ⟨hal-00275210⟩
  • Isidore P. Decostaire, Dominique Lelièvre, Vincent Aucagne, Agnès F. Delmas. Synergic effect of hydride and proton donors in the Pd(0)-mediated deprotection of Nα-Aloc proline derivatives. Tetrahedron Letters, 2007, 48, pp.6523-6526. ⟨10.1016/j.tetlet.2007.07.061⟩. ⟨hal-00166600⟩
  • Julie Broggi, Nicolas Joubert, Vincent Aucagne, Sabine Berteina-Raboin, S. Diez-Gonzalez, et al.. Alkyne-Azide Click Chemistry Mediated Carbanucleosides Synthesis. Nucleosides, Nucleotides and Nucleic Acids, 2007, 26 (10-12), pp.1391-1394. ⟨10.1080/15257770701534139⟩. ⟨hal-02086003⟩
  • J. Broggi, N. Joubert, Vincent Aucagne, T. Zevaco, S. Berteina-Raboin, et al.. Study of different copper(I) catalysts for the "click chemistry" approach to carbanucleosides. Nucleosides, Nucleotides and Nucleic Acids, 2007, 26, pp.779-783. ⟨hal-00275217⟩
  • Vincent Aucagne, Kevin Hänni, David Leigh, Paul Lusby, D Barney Walker. Catalytic “Click” Rotaxanes: A Substoichiometric Metal-Template Pathway to Mechanically Interlocked Architectures. Journal of the American Chemical Society, 2006, 128 (7), pp.2186-2187. ⟨10.1021/ja056903f⟩. ⟨hal-02086010⟩
  • Vincent Aucagne, David A. Leigh. Chemoselective formation of successive triazole linkages in one pot: "click-click" chemistry. Organic Letters, 2006, 8 (20), pp.4505-4507. ⟨10.1021/ol061657d⟩. ⟨hal-00387909⟩
  • Vincent Aucagne, David Leigh, Julia Lock, Andrew Thomson. Rotaxanes of Cyclic Peptides. Journal of the American Chemical Society, 2006, 128 (6), pp.1784-1785. ⟨10.1021/ja057206q⟩. ⟨hal-02086005⟩
  • Vincent Aucagne, Franck Amblard, Luigi Agrofoglio. Highly Efficient AgNO3-Catalyzed Preparation of Substituted Furanopyrimidine Nucleosides [cf. (III)].. ChemInform, 2005, 36 (18), ⟨10.1002/chin.200518181⟩. ⟨hal-02086027⟩
  • V. Aucagne, C. Lorin, A. Tatibouët, P. Rollin. Regioselective Michael-induced cyclisation of γ- and δ-hydroxy vinyl sulfides and vinyl dithiocarbamates. Tetrahedron Letters, 2005, 46 (25), pp.4349-4352. ⟨10.1016/j.tetlet.2005.04.112⟩. ⟨hal-02086017⟩
  • Franck Amblard, Vincent Aucagne, Pierre Guenot, Raymond Schinazi, Luigi Agrofoglio. Synthesis and antiviral activity of novel acyclic nucleosides in the 5-alkynyl- and 6-alkylfuro[2,3-d]pyrimidine series. Bioorganic and Medicinal Chemistry, 2005, 13 (4), pp.1239-1248. ⟨10.1016/j.bmc.2004.11.057⟩. ⟨hal-02086014⟩
  • Vanessa Escuret, Vincent Aucagne, Nicolas Joubert, David Durantel, Kimberly Rapp, et al.. Synthesis of 5-haloethynyl- and 5-(1,2-dihalo)vinyluracil nucleosides: Antiviral activity and cellular toxicity. Bioorganic and Medicinal Chemistry, 2005, 13 (21), pp.6015-6024. ⟨10.1016/j.bmc.2005.06.021⟩. ⟨hal-02086013⟩
  • Vincent Aucagne, Arnaud Tatibouët, Patrick Rollin. Wittig approach to carbohydrate-derived vinyl sulfides, new substrates for regiocontrolled ring-closure reactions. Tetrahedron, 2004, 60 (8), pp.1817-1826. ⟨10.1016/j.tet.2003.12.040⟩. ⟨hal-02086021⟩
  • Vincent Aucagne, Sabine Berteina-Raboin, Pierre Guenot, Luigi Agrofoglio. Palladium-Catalyzed Synthesis of Uridines on Polystyrene-Based Solid Supports. Journal of Combinatorial Chemistry, 2004, 6 (5), pp.717-723. ⟨10.1021/cc049976o⟩. ⟨hal-02086022⟩
  • Isabelle Gillaizeau, Irene m. Lagoja, Steve p. Nolan, Vincent Aucagne, Jef Rozenski, et al.. Straightforward Synthesis of Labeled and Unlabeled Pyrimidine d4Ns via 2′,3′-Diyne seco Analogues through Olefin Metathesis Reactions. European Journal of Organic Chemistry, 2003, 2003 (4), pp.666-671. ⟨10.1002/ejoc.200390107⟩. ⟨hal-02086029⟩
  • Vincent Aucagne, Maria Aversa, Anna Barattucci, Paola Bonaccorsi, Placido Giannetto, et al.. Sulfenic acids in the carbohydrate field. Synthesis of transient glycosulfenic acids and their addition to unsaturated acceptors.. Journal of Organic Chemistry, 2002, 67 (20), pp.6925-30. ⟨hal-02086034⟩
  • Vincent Aucagne, David Gueyrard, Arnaud Tatibouët, Alain Quinsac, Patrick Rollin. Synthetic Approaches to C-Glucosinolates. Tetrahedron, 2000, 56 (17), pp.2647-2654. ⟨10.1016/S0040-4020(00)00153-8⟩. ⟨hal-02086037⟩
  • V. Aucagne, D. Gueyrard, A. Tatibout, S. Cottaz, H. Driguez, et al.. the first synthesis of c-glucotropeolin. Tetrahedron Letters, 1999, pp.7319-7321. ⟨hal-00309763⟩

Communication dans un congrès39 documents

  • Ross Ballantine, Ameni Hadj Mohamed, Mingxiang Zhu, Aromal Asokan, Linhua Shen, et al.. Palladium-mediated S-arylation and S-allylation for late-stage peptide functionalisation and protein conjugation. 37. European Peptide Symposium. 14. International Peptide Symposium, Aug 2024, Florence, Italy. pp.692-P2.010. ⟨hal-05075799⟩
  • Noémie de San Nicolas, A. Jouault, Aromal Asokan, Lhousseine Touqui, K Loth, et al.. Big-Defensin Diversification in Oysters: Implications for Host Defense and Microbiota Management (D. Destoumieux-Garzon INVITED SPEAKER). IMAP 2024 International Meeting on Antimicrobial Peptides, Sep 2024, Londres, United Kingdom. ⟨hal-04882843⟩
  • Hugo Terrasson, Karine Loth, Nicolas Parisot, Françoise Paquet, Isabelle Rahioui, et al.. Bacteriocyte-specific Cysteine-Rich (BCR) peptides form a new aphid-specific defensin-like family and are promising regulators of aphid symbiosis. Rencontres du Réseau Ecologie des Interactions Durables (REID), May 2023, Poitiers, France. ⟨hal-04633283⟩
  • Noémie de San Nicolas, Aromal Asokan, Rafaela da Rosa, Vincent Aucagne, K. Loth, et al.. Big defensins: A Diversified Family of Antimicrobial Peptides Confronting Versatile Microbial Environments (DELPHINE DESTOUMIEUX-GARZON INVITED SPEAKER). Antimicrobial Peptides. Yesterday, Today, and Tomorrow, Oct 2023, Omaha, Nebraska, USA, United States. ⟨hal-04885227⟩
  • Noémie de San Nicolas, A. Asokan, R.D. Rosa, S.N. Voisin, Marie Agnès Travers, et al.. Functional DIversification of Big-Defensins and the shaping of oyster microbiota. AMP 2022 7th International Symposium on Antimicrobial Peptides, Nov 2022, Paris, France. ⟨hal-03976756⟩
  • Hugo Terrasson, Karine Loth, Nicolas Parisot, Françoise Paquet, Isabelle Rahioui, et al.. Peptides « Bacteriocyte-specific Cysteine Rich » (BCR) : un rôle dans le contrôle de la symbiose ? Focus sur BCR4 chez le puceron du pois.. 12èmes rencontres du réseau français de Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), May 2022, Nice, France. ⟨hal-04771966⟩
  • Hugo Terrasson, Karine Loth, Nicolas Parisot, Françoise Paquet, Isabelle Rahioui, et al.. Les peptides « Bacteriocyte-specific Cystein-Rich » : une nouvelle famille de défensine. Régulateurs de la symbiose chez les pucerons ?. 9ème Journées du GDR "MultiFonction des Peptides AntiMicrobiens" (MuFoPAM), Oct 2022, Amboise, France. ⟨hal-04633233⟩
  • A. Asokan, Noémie de San Nicolas, H. Meudal, K. Loth, Delphine Destoumieux-Garzon, et al.. Enabling the synthesis of hydrophobic proteins using NCL-labile solubilizing tags: a case study of Crassostrea gigas big defensin 3. 22nd GFPP & 5th BPGM French-Belgian Joint Meeting, Groupe Français des Peptides et Protéines, May 2022, Port Leucate, France. ⟨hal-03976595⟩
  • Vincent Aucagne. A chemical toolbox for simplifying chemical protein synthesis. Congrès annuel de la Société Française de Biochimie et Biologie Moléculaire (SFBBM21), Jul 2021, Paris, France. ⟨hal-03563426⟩
  • Josef Hamacek, Edina Numanovic, Vincent Aucagne. Determination of Binding Affinities with Flow-Induced Dispersion Analysis: The Case of Synthetic Affibodies. NECTAR, annual meeting, Aug 2021, Lisbon, Portugal. ⟨hal-03482197⟩
  • Vincent Aucagne. Développements méthodologiques pour la synthèse chimique de protéines. 33e colloque Biotechnocentre, Oct 2021, Chaumont-sur-Tharonne, France. ⟨hal-03563421⟩
  • David Montoir, Mehdi Amoura, Zine El Abidine Ababsa, T.M. Vishwanatha, Expédite Yen-Pon, et al.. Synthesis of aryl-thioglycopeptides through chemoselective Pd-mediated conjugation. 4. GFPP Chemical Ligation Meeting (Ligation2020), Jan 2020, Orléans, France. ⟨hal-02892772⟩
  • S. Abboud, Mehdi Amoura, V. P. Terrier, A. F. Delmas, V. Aucagne. An improved synthesis of N-Hnb-Cys peptide crypto-thioesters ‒studies on the epimerization of cysteine during solid-phase reductive amination. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02892784⟩
  • Vincent Aucagne. Séminaire invité : Development of a molecular toolbox to simplify the chemical synthesis of proteins. Institut de Chimie des Substances Naturelles, Mar 2019, Gif-sur-Yvette, France. ⟨hal-02974369⟩
  • S. Abboud, V. Piller, S. Papot, V. Aucagne. Développement de bras enzymo-labiles pour la synthèse totale de protéines par ligations chimiques sur support solide. 32e Colloque Biotechnocentre, Oct 2019, Seillac, France. ⟨hal-02893386⟩
  • K Loth, Agnès Vergnes, C Barreto, S Voisin, H. Meudal, et al.. Exploring ancestral traits lost during molecular evolution of Big-Defensins Towards β-defensins (DELPHINE DESTOUMIEUX-GARZON, INVITED SPEAKER). Gordon Research Conference "Antimicrobial Peptides", Feb 2019, Barga, Italy. ⟨hal-04891216⟩
  • D. Montoir, Mehdi Amoura, A. Ababsa Z. E., M. Vishwanatha T., E. Yen-Pon, et al.. ”Tag and modify” strategy for the Pd-catalyzed Thioglycoconjugation of peptides. Noncanonical amino acids (ncAAs): Tools for biological and biophysical investigations, Oct 2019, Paris, France. ⟨hal-02892775⟩
  • H. Meudal, Nicolas Guyot, K. Loth, G. Jousset, S. Trapp, et al.. Gga-AvBD11, the archetype of a new structural family of defensins. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02892790⟩
  • G. Lalmanach, M. Wartenberg, M. Galibert, A. Saidi, F. Lecaille, et al.. Design of both pseudopeptide inhibitors and imaging probes derived from a unique substrate sequence: a versatile molecular toolbox for studying proteases. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02892793⟩
  • Mehdi Amoura, D. Sarraf, L. Nauton, V.P. Terrier, D. Lelièvre, et al.. N-2-hydroxybenzyl-cysteine peptide crypto-thioesters for native chemical ligation. 35th European Peptide Symposium (EPS35), Aug 2018, Dublin, Ireland. ⟨hal-02892802⟩
  • Nicolas Guyot, Hervé Meudal, Karine Loth, Guillaume Jousset, Anne Silvestre, et al.. 1ère structure 3D d’une défensine à double motif β-défensine, Gga-AvBD11 du poulet Gallus gallus, et explorations fonctionnelles. 5es Journées GDR MuFoPAM, Centre National de la Recherche Scientifique (CNRS). FRA., Oct 2018, Paris, France. ⟨hal-02788993⟩
  • Vincent Aucagne. Séminaire invité : Développement d’une boîte à outils pour simplifier la synthèse chimique de protéines. Institut des Biomolécules Max Mousseron, Nov 2018, Montpellier, France. ⟨hal-02974372⟩
  • Julien Diharce, Mickaël Cueto, Vincent Aucagne, Massimiliano Beltramo, Pascal Bonnet. Fragment covalent docking (FCD) approach: An innovative in silico tools for the prediction of peptide-protein interaction. 256th National Meeting and Exposition of the American-Chemical-Society Nanoscience, Nanotechnology and Beyond (ACS), American Chemical Society (ACS). USA., Aug 2018, Boston, United States. pp.2. ⟨hal-02734800⟩
  • T.M. Vishwanatha, C. Decourt, V.P. Terrier, V. Robert, M. Galibert, et al.. Rational design of kisspeptin analogs for the control of reproduction. 4th Belgian Peptide Group Meeting, Feb 2018, Bruxelles, Belgium. ⟨hal-02892809⟩
  • A.F. Delmas, Vincent Aucagne. Synthesis and structural characterization of naturally-occuring disulfide rich antimicrobial peptides Gyros Protein Technologies. European peptide symposium, Aug 2018, Dublin, Ireland. ⟨hal-02919154⟩
  • Vincent Aucagne. Séminaire invité : Development of a molecular toolbox to simplify the chemical synthesis of proteins and constrained peptides natural products. Vrije Universiteit Brussel, May 2017, Bruxelles, Belgium. ⟨hal-02974374⟩
  • Vincent Aucagne. Séminaire invité : Développement d'une boîte à outils pour simplifier la synthèse chimique de protéines. Laboratoire BioCIS - Biomolécules : Conception, Isolement et Synthèse, Université Paris-Sud, Apr 2017, Châtenay-Malabry, France. ⟨hal-02974390⟩
  • A. Casas-Mora, M. Galibert, A.F. Delmas, V. Aucagne. A non-chromatographic catch-and-release purification method to simplify the synthesis of cysteine-rich peptides. 20e réunion du Groupe Français des Peptides et des Protéines (GFPP 20), Mar 2017, Arcachon, France. ⟨hal-02893392⟩
  • Vincent Aucagne. Séminaire invité : Development of a molecular toolbox to simplify the chemical synthesis of proteins and constrained peptides natural products. Institut Européen de Chimie et Biologie, Apr 2017, Bordeaux, France. ⟨hal-02974400⟩
  • Vincent Aucagne. Séminaire invité : Triazolopeptides as proteolysis-resistant, highly potent KISS1R agonists. Universiteit Gent, May 2017, Gand, Belgium. ⟨hal-02974376⟩
  • Vincent Aucagne. Simplifier la synthèse totale de protéines et de mini-protéines riches en pont disulfures. 7e Symposium Francophone de Synthèse Totale (SFST7), Jun 2017, Orsay, France. ⟨hal-02892762⟩
  • Vincent Aucagne. Séminaire invité : A molecular toolbox for exploring new chemical spaces: making simpler the synthesis of biologically- and therapeutically-relevant small proteins and complex peptides. Sanofi, Sep 2016, Francfort, Germany. ⟨hal-02974403⟩
  • A.F. Delmas, V.P. Terrier, R.D. Rosa, A. Bressan, P. Marceau, et al.. Native Chemical ligation simplifies the access of multidomain antimicrobial peptides: application to the study of big-defensins. International symposium on AntiMicrobial Peptides (AMP2016), Jun 2016, Montpellier, France. ⟨hal-02892834⟩
  • Vincent Aucagne. Séminaire invité : Development of a molecular toolbox to simplify the chemical synthesis of proteins.. Institut Curie, Jun 2016, Paris, France. ⟨hal-02974405⟩
  • Massimiliano Beltramo, Vincent Aucagne, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, et al.. Design and profiling of new selective KISS1R agonists that stimulate the reproductive system. 8. International Congress of Neuroendocrinology, Society for Behavioral Neuroendocrinology (SBN). USA., Aug 2014, Sydney, Australia. ⟨hal-02738894⟩
  • Massimiliano Beltramo, Vincent Aucagne, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, et al.. New KISS1R agonists with potential for the treatment of reproductive disorder. 11. International Symposium on GnRH: The hypothalamic-pituitary-gonadal axis in cancer and reproduction, Kenes International. USA., Feb 2014, Salzburg, Austria. ⟨hal-02742248⟩
  • Chrystelle Derache, Hervé Meudal, Vincent Aucagne, Martine Cadène, Agnès Delmas, et al.. First insights into the structure-activity relationships of avian beta-defensins.. 2nd International Symposium on Antimicrobial Peptides - Food Veterinary Medical and Novel Applications., 2009, Saint-Malo, France. ⟨hal-02753345⟩
  • Anne-Christine Lalmanach, Chrystelle Derache, Evelyne Esnault, Valérie Labas, V. Aucagne, et al.. Avian beta-defensins in the control of bacterial pathogens of chicken digestive tract. 2. International Symposium on Antimicrobial Peptides. Food Veterinary Medical and Novel Applications, Jun 2009, Saint-Malo, France. ⟨hal-02751627⟩
  • P. da Silva, I. Rahioui, C. Laugier, Yvan Rahbé, A. Delmas, et al.. PA1b, un peptide à activité insecticide : relations structure/fonction. XVème Colloque de Physiologie de l'Insecte, 2007, Rennes (France), juillet 2007, France. pp.1-1. ⟨hal-00391295⟩

Poster57 documents

  • Hugo Terrasson, Karine Loth, Nicolas Parisot, Françoise Paquet, Isabelle Rahioui, et al.. The aphid BCR4 structure and activity uncover a new defensin peptide superfamily. XXVII International Congress of Entomology, Aug 2024, Kyoto, Japan. ⟨hal-04702878⟩
  • El Hadji Cisse, Pierre Prieu-Serandon, Marcin J Suskiewicz, Vincent Aucagne. A semi-synthetic pathway to SUMOylated protein mimics. EMBO Workshop: Ubiquitin and ubiquitin-like proteins in health and disease, Sep 2024, Cavtat & Dubrovnik, Croatia. ⟨hal-05217596⟩
  • Hugo Terrasson, Karine Loth, Françoise Paquet, Nicolas Parisot, Isabelle Rahioui, et al.. The Bacteriocyte-specific Cysteine-Rich (BCR) proteins: a role in the control of aphid symbiosis ?. Journée scientifique enjeu « santé globale et bio‐ingénierie » de l'INSA Lyon, Apr 2023, Villeurbanne, France. ⟨hal-04633269⟩
  • Hugo Terrasson, Karine Loth, Nicolas Parisot, Françoise Paquet, Isabelle Rahioui, et al.. Bacteriocyte specific Cystein Rich peptides, a new defensin like protein family , are promising regulators of aphid symbiosis. 10th congress of the International Symbiosis Society (ISS) - 3rd International Conference on Holobionts (joint meeting), Jul 2022, Lyon, France. ⟨hal-04771990⟩
  • Noémie de San Nicolas, A Asokan, S Voisin, A Delmas, Vincent Aucagne, et al.. Role of big-defensins in the control of oyster microbiota. 8ème journées du GDR MuFoPAM, Oct 2021, Marseille, France. . ⟨hal-04888804⟩
  • S. Abboud, A.F. Delmas, V. Aucagne. Synthesis of N-Hnb-Cys peptide crypto-thioesters: identification of imadozolidinone and epimerized side products, and development of an optimized protocol. 4th GFPP Chemical Ligation Meeting (Ligation2020), Jan 2020, Orléans, France. ⟨hal-02893398⟩
  • S. Abboud, Mehdi Amoura, V.P. Terrier, A.F. Delmas, V. Aucagne. An improved synthesis of N-Hnb-Cys peptide crypto-thioesters - studies on the epimerization of cysteine during solid-phase reductive amination. 8th Chemical Protein Synthesis meeting (CPS2019), Jun 2019, Berlin, Germany. ⟨hal-02893426⟩
  • S. Abboud, Mehdi Amoura, P. Terrier V., A.F. Delmas, V. Aucagne. N-Hnb-Cys peptide crypto-thioesters: optimized synthetic protocol and second generation device. Noncanonical amino acids (ncAAs): Tools for biological and biophysical investigations, Oct 2019, Paris, France. ⟨hal-02893409⟩
  • Herve Meudal, Françoise Paquet, Laurence Jouvensal, V. Aucagne, A.F. Delmas, et al.. Chemical synthesis and natural abundance NMR: an efficient tandem to unravel 3D structures of unlabeled disulfide rich peptides. 21e congrès du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02919180⟩
  • T.M. Vishwanatha, D. Montoir, Mehdi Amoura, Z. El Ababsa, E. Yen-Pon, et al.. Synthesis of aryl-thioglycopeptides through chemoselective Pd-catalyzed conjugation. 26. American Peptide Symposium (APS 2019), Jun 2019, Monterey, Californie, United States. ⟨hal-02893419⟩
  • Vincent Robert, Vishwanatha Thimmalapura Marulappa, Didier Lomet, Caroline Decourt, Laia Miret, et al.. Design of GPR54 (Kiss1r) crosslinker peptides: new tools to study G protein-coupled receptors (GPCR) localization and function. SNE, Oct 2019, Tours, France. ⟨hal-03381932⟩
  • H. Meudal, K. Loth, G. Jousset, V. Aucagne, Nicolas Guyot, et al.. A new structural family for antimicrobial defensins. NMR : a tool for biology XIth, Jan 2019, Paris, France. ⟨hal-02919171⟩
  • Françoise Paquet, K. Loth, C. Arnoult, V. Aucagne, A.F. Delmas. Spermaurin, a scorpion venom disulfide-rich miniprotein that improves sperm motility and fertilization in mammals.. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02893462⟩
  • F. Coste, G. Chaume, J.-B. Madinier, I. Rahioui, B. Castaing, et al.. Incorporation of trifluoromethylated pseudoproline in an entomotoxic knottin: effects on oxidative folding, 3D structure and biological activity. 21e congrès du Groupe Français des Peptides et des Protéines (GFPP), May 2019, Amboise, France. ⟨hal-02893471⟩
  • T.M. Vishwanatha, D. Montoir, Mehdi Amoura, Z. El Ababsa, E. Yen-Pon, et al.. Synthesis of aryl-thioglycopeptides through chemoselective Pd-catalyzed conjugation. 21. Réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02893488⟩
  • Massimiliano Beltramo, Caroline Decourt, Vincent Robert, Didier Lomet, Vincent Aucagne. In non-breeding ewes the kisspeptin analog c6 triggers ovulation without progestogen priming. 9th International Congress of Neuroendocrinology, Jul 2018, Toronto, Canada. , 2018, The 9th International Congress of Neuroendocrinology. Abstract book. ⟨hal-02735160⟩
  • F. Coste, G. Chaume, J.-B. Madinier, I. Rahioui, B. Castaing, et al.. Incorporation of trifluoromethylated pseudoproline in an entomotoxic knottin: effects on oxidative folding, 3D structure and biological activity. 35th European Peptide Symposium (EPS35), Aug 2018, Dublin, Ireland. ⟨hal-02894161⟩
  • Mehdi Amoura, V.P. Terrier, A.F. Delmas, V. Aucagne. N-2-Hydroxybenzyl-Cysteine Peptides as Efficient Thioester Surrogates for Native Chemical Ligation. 4th Belgian Peptide Group Meeting, Feb 2018, Bruxelles, Belgium. ⟨hal-02894279⟩
  • H. Meudal, Laurence Jouvensal, K. Loth, Françoise Paquet, V. Aucagne, et al.. Chemical synthesis and natural abundance NMR: An efficient tandem to unravel 3D structures of Disulfide Rich Miniproteins. 35th European Peptide Symposium, Aug 2018, Dublin, Ireland. ⟨hal-02920483⟩
  • David Montoir, Mehdi Amoura, Zine El Abidine Ababsa, Thimmalapura Marulappa Vishwanatha, Expédite Yen-Pon, et al.. Synthesis of aryl-Thioglycopeptides through chemoselective Pd-catalyzed conjugation. 35 th European Peptide Symposium, Aug 2018, Dublin, Ireland. 2018. ⟨hal-02734043⟩
  • S.V. Eliseeva, V. Aucagne, A.F. Delmas, S. Petoud, I. Gillaizeau. Near-infrared emitting lanthanide molecules, macromolecules and nanomaterials: New perspectives of optical biological imaging of living systems. GDR AIm 2018 - 1ères Journées du GDR AİM: "Agents d'imagerie moléculaire", Jun 2018, Orléans, France. ⟨hal-03326661⟩
  • S. Abboud, V. Piller, S. Papot, A.F. Delmas, V. Aucagne. Development of chemo-enzymatic methodologies for the total synthesis of proteins through solid-supported chemical ligation. 31e Colloque Biotechnocentre, Oct 2018, Seillac, France. ⟨hal-02894152⟩
  • T.M. Vishwanatha, C. Decourt, V.P. Terrier, V. Robert, J.-B. Madinier, et al.. Rational design of kisspeptin analogs for the control of the reproductive system. 25th SCT Young Research Fellows meeting, Mar 2018, Orléans, France. ⟨hal-02894277⟩
  • C. Decourt, V. Robert, Didier Lomet, V. Aucagne, Massimiliano Beltramo. The kisspeptin analog C6 triggers ovulation in non-breeding ewe in the absence of progestogen priming. 9. International Congress of Neuroendocrinology (ICN 2018), Jul 2018, Toronto, Canada. ⟨hal-02894264⟩
  • R. Cameron, R. Kirkwood, M. Beltramo, V. Aucagne, A. Tilbrook. A single injection of compound 6 evoked an LH surge and ovulation in 18 week old gilts. 100th annual meeting of the Endocrine Society (ENDO 2018), Mar 2018, Chicago, Illinois, United States. Endocrine Reviews, 39 (Suppl. 1), pp.281-282, The Endocrine Society’s 100th Annual Meeting and Expo. ⟨10.1093/edrv/39.supp.1⟩. ⟨hal-02894272⟩
  • Mehdi Amoura, V.P. Terrier, A.F. Delmas, V. Aucagne. Design and optimization of alternative thioester precursors to simplify protein synthesis by native chemical ligation. 25th SCT Young Research Fellows meeting, Mar 2018, Orléans, France. ⟨hal-02894273⟩
  • Mehdi Amoura, V.P. Terrier, A.F. Delmas, V. Aucagne. Second generation N-2-hydroxybenzyl-cysteine peptide crypto-thioesters for native chemical ligation. 35th European Peptide Symposium (EPS35), Aug 2018, Dublin, Ireland. ⟨hal-02894157⟩
  • T.M. Vishwanatha, C. Decourt C, V. Robert, M. Galibert, J.-B. Madinier, et al.. Long-lasting increase of gonadotropins by rational design of lipophilic kisspeptin analogs. 2018 International Symposium on Chemical Biology, Jan 2018, Genève, Switzerland. ⟨hal-02894282⟩
  • Françoise Paquet, H. Meudal, Laurence Jouvensal, K. Loth, V. Aucagne, et al.. Synthèse chimique et RMN en abondance naturelle : un tandem efficace pour résoudre les structures 3D de peptides/protéines riches en ponts disulfure. 5es journées annuelles du GDR MuFoPAM, Oct 2018, Paris, France. ⟨hal-02920025⟩
  • A.F. Delmas, K. Loth, Herve Meudal, V.P. Terrier, R.D. Rosa, et al.. NCL-based synthesis, 3D structure and first insight into antimicrobial properties of Cg-BigDef1, an oyster big defensin active at high salinity. 20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France. ⟨hal-02894301⟩
  • Caroline Decourt, Vincent Robert, Didier Lomet, Vincent Aucagne, Greg Anderson, et al.. Investigation of a kisspeptin analog effects both on synchronization of ovulation and puberty onset in domestic mammals and in rodents. ReproSciences 2017, Apr 2017, Tours, France. 75 p., 2017, 2èmes Journées Scientifiques du GdR Repro. ⟨hal-01603310⟩
  • Mehdi Amoura, V. P. Terrier, A.F. Delmas, Vincent Aucagne. Second generation N-2-hydroxybenzyl-cysteine peptide crypto-thioesters: achieving very fast NCL kinetics at neutral pH. 20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France. ⟨hal-02453275⟩
  • A. Casas-Mora, M. Galibert, A.F. Delmas, V. Aucagne. Design of a New N-Terminal Linker for the Capture-and-Release Purification of Biologically-Relevant Disulfide-Rich Peptides. 25th American Peptide Symposium (APS 25), Jun 2017, Whistler, Canada. ⟨hal-02894295⟩
  • Vincent Robert, Vincent Aucagne, Caroline Decourt, Massimiliano Beltramo. Do endogenous kisspeptins and synthetic agonist C6 trigger different intracellular responses?. 42e colloque de la société de neuroendocrinologie (SNE 2017), Sep 2017, Dijon, France. 2017, 42ème Colloque de la Société de Neuroendocrinologie. ⟨hal-02733747⟩
  • Vincent Aucagne, E. Schmitt, P. Bulet, C. Arnoult.. NCL-based total synthesis of spermaurin, a scorpion venom disulfide-rich miniprotein that improves sperm motility and fertilization in mammals. 20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France. . ⟨hal-02453195⟩
  • Caroline Decourt, Vincent Robert, Didier Lomet, Karine Anger, A. Delmas, et al.. Investigation of tachyphylaxis of LH response following repeated injections of the kisspeptin analog C6. Colloque International NeuroFrance 2017, May 2017, Bordeaux, France. 2017, Colloque International NeuroFrance 2017. ⟨hal-01605114⟩
  • C. Decourt, V. Robert, D. Lomet, Vincent Aucagne, G. Anderson, et al.. Pattern of LH secretion after repeated treatment with kisspeptin analog C6 reveals differential sensitivity between mice and ewes. 42. Colloque de la société de neuroendocrinologie (SNE 2017), Sep 2017, Dijon, France. ⟨hal-02894288⟩
  • Mehdi Amoura, V.P. Terrier, D. Lelièvre, A.F. Delmas, V. Aucagne. N-2-Hydroxybenzyl-Cysteine Peptides as Efficient Thioester Surrogates for Native Chemical Ligation. 25th American Peptide Symposium (APS 25), Jun 2017, Whistler, Canada. ⟨hal-02894293⟩
  • Mehdi Amoura, V.P. Terrier, D. Lelièvre, A.F. Delmas, V. Aucagne. N-2-Hydroxybenzyl-Cysteine Peptides as Efficient Thioester Surrogates for Native Chemical Ligation. 7th Chemical Protein Synthesis meeting (CPS 2017), Sep 2017, Haifa, Israel. ⟨hal-02894290⟩
  • A. Delmas, K. Loth, Herve Meudal, V. Terrier, R.D. Rosa, et al.. NCL-based synthesis, 3D structure and first insight into antimicrobial properties of Cg-BigDef1, an oyster big defensin active at high salinity. NMR: a tool for Biology Xth, Jan 2017, Paris, France. ⟨hal-02453460⟩
  • N. J. Stanley, D. Lelièvre, A.F. Delmas, Vincent Aucagne. Development of highly base-labile linkers for the catch-and-release purification of difficult peptides. Application to Avian beta-defensin 2. 20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France. . ⟨hal-02453245⟩
  • Agnes Vergnes, Victor P. Terrier, Bressan Albert, Rafael Diego Rosa, Vincent Aucagne, et al.. Laligation native simplifie l’étude de l’activité etdu mécanismed’action des peptides antimicrobiens à multiples domaines :cas des Big défensines d’huître.. IIIèmes journées annuelles MuFoPAM « MultiFonction des Peptides AntiMicrobiens », Oct 2016, Tours, France. ⟨hal-02128427⟩
  • A.F. Delmas, V.P. Terrier, R.D. Rosa, A. Bressan, P. Marceau, et al.. Native Chemical ligation simplifies the access of multi-domain antimicrobial peptides: application to the study of big-defensins. 34th European Peptide Symposium 2016 (EPS2016), Sep 2016, Leipzig, Germany. ⟨hal-02895296⟩
  • V. P. Terrier, H. Adihou, D. Lelièvre, Mehdi Amoura, A.F. Delmas, et al.. A straightforward strategy for automated Fmoc-based synthesis of peptide “crypto-thioesters”. Application to the total synthesis of biologically-relevant disulfide-rich peptides. Journées de Chimie Organique de la Société Chimique de France (JCO2016), Dec 2016, Palaiseau, France. . ⟨hal-02453318⟩
  • M. Beltramo, V. Robert, D. Lomet, K. Anger, M. Galibert, et al.. A new selective kisspeptin analog, C6, that advance puberty in mice and stimulate fertile ovulation in ewe. British Society for Neuroendocrinology Annual Meeting, Sep 2016, Glasgow, United Kingdom. ⟨hal-02453336⟩
  • Caroline Decourt, Vincent Robert, Didier Lomet, Karine Anger, M. Galibert, et al.. Induction of fertile ovulation and puberty advancement by a new kisspeptin analog. 18th International Congress on Animal Reproduction (ICAR), Jun 2016, Tours, France. 676 p., 2016, 18th International Congress on Animal Reproduction (ICAR). ⟨hal-01604087⟩
  • A. Casas-Mora, M. Galibert, A.F. Delmas, V. Aucagne. A capture-and-release purification strategy to simplify the synthesis of disulfide-rich peptides. 1st PSL Chemical Biology Meeting, Dec 2016, Paris, France. . ⟨hal-02453303⟩
  • Vincent Aucagne, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, P. Marceau, et al.. Rational design of triazolo-lipopeptides analogs of kisspeptin inducing a long-lasting increase of gonadotrophins. 19. Congrès du Groupe Français des Peptides et des Protéines, May 2015, Port-Bail, United States. 2015. ⟨hal-02793091⟩
  • Caroline Decourt, Vincent Robert, Didier Lomet, Karine Anger, Mathieu Galibert, et al.. Induction of synchronized fertile ovulation by a new selective agonist of kisspeptin receptor. 1 Journées du GdR 3606 Repro, Apr 2015, Rennes, France. 105 p., 2015, 1ères Journées Scientifiques du GdR Repro. ⟨hal-02742326⟩
  • Vincent Aucagne, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, P. Marceau, et al.. Rational design of triazolo-lipopeptides analogs of kisspeptin inducing a long-lasting increase of gonadotropins. 24. Meeting of the American Peptide Society, Jun 2015, Orlando, United States. 2015, 24th Meeting of the American Peptide Society. ⟨hal-02741835⟩
  • Caroline Decourt, Karine Anger, Vincent Robert, Vincent Aucagne, Mathieu Galibert, et al.. Development of new kisspeptin analogs to stimulate the reproductive system. International Conference on Gonadotropins & Receptors, Sep 2014, Tours, France. , 2014, ICGRIII International Conference on Gonadotropins & Receptors. ⟨hal-02744014⟩
  • Massimiliano Beltramo, V. Aucagne, R. Vincent, M. Galibert, J.B. Madinier, et al.. La kisspeptine : une nouvelle voie pour maitriser l’ovulation chez les petits ruminants ?. 5. Journées d'Animation Scientifique du département Phase (JAS Phase 2013), Oct 2013, Paris, France. 2013. ⟨hal-02805330⟩
  • Mathieu Galibert, Chrystelle Derache, Franck Coste, Hervé Meudal, Anne-Christine Lalmanach, et al.. Improvement of the chemical production of β-defensins including straightforward attribution of disulfide bridges. 18. Réunion du GFPP, May 2013, Sète, France. 1 p., 2013. ⟨hal-02805308⟩
  • Massimiliano Beltramo, V. Aucagne, Vincent Robert, M. Galibert, J.B. Madinier, et al.. Design and functional profiling of new KISS1R agonists. 2. Annual Meeting of the GDR RCPG-PhysioMed, Oct 2013, Illkirch, France. 2013, 2nd Annual Meeting of the GDR RCPG-PhysioMed. ⟨hal-02745908⟩
  • M. Galibert, Chrystelle Derache, F. Coste, H. Meudal, Anne-Christine Lalmanach, et al.. Improvement of the chemical production of β-defensins including straighforward attribution of disulfide bridges. 3. International Symposium on Antimicrobial Peptides: Today knowledge and future applications, Jun 2012, Lille, France. , pp.C-43, 2012, AMP 2012 - Antimicrobial peptide symposium. ⟨hal-02748134⟩
  • Chrystelle Derache, Emmanuel Kut, Hervé Meudal, Vincent Aucagne, Agnès Delmas, et al.. Antibacterial spectrum of avian defensin 2: peculiarities in relationship with structural features. 3. International Symposium on Antimicrobial Peptides: Today knowledge and future applications (AMP 2012), Jun 2012, Lille, France. , pp.D-97, 2012. ⟨hal-02807349⟩
  • Chrystelle Derache, Hervé Meudal, Vincent Aucagne, Anne-Christine Lalmanach, Céline Landon, et al.. Synthesis and oxidative folding of functional miniproteins containing three disulfide bridges. 21e Colloque Biotechnocentre, 2008, Seillac, France. 1 p, 2008. ⟨hal-02818274⟩

Chapitre d'ouvrage2 documents

  • S. Abboud, A.F. Delmas, V. Aucagne. Solid phase chemical ligation. Brik Asharf, Dawson Philip, Liu Lei. Total Chemical Protein Synthesis, Wiley, 2021, 978-3-527-34660-8. ⟨hal-02974365⟩
  • Vincent Aucagne. (9H‐Fluoren‐9‐yl)methanethiol. Encyclopedia of Reagents for Organic Synthesis, John Wiley & Sons, Ltd, 2011, ⟨10.1002/047084289X.rn01287⟩. ⟨hal-02071829⟩

Brevet3 documents

  • Nicolas Guyot, Sophie Réhault-Godbert, Anne Silvestre, Sascha Trapp, Sophie Iochmann, et al.. Peptides dérivés d'une beta-défensine 11 aviaire et leurs utilisations. France, N° de brevet: WO 2020/030773 A1. AMV; SA, 3IMo, AIM. 2020. ⟨hal-02595638⟩
  • Massimiliano Beltramo, Vincent Aucagne, Alain Caraty, Agnès Delmas, Mathieu Galibert. KISS1R receptor agonist compounds and use thereof for inducing ovulation in mammals. Patent n° : WO2014118318 (A1). 2014, 49 p. + 12 p. annexes. ⟨hal-02793004⟩
  • Massimiliano Beltramo, Vincent Aucagne, Alain Caraty, Agnès Delmas. Composés agonistes du récepteur KISS1R et leur utilisation pour induire l’ovulation chez les mammiféres. N° de brevet: FR3001455 (A1). 2013, 34 p. + 10 p. annexes. ⟨hal-02808772⟩

Pré-publication, Document de travail1 document

  • El Hadji Cisse, Vincent Aucagne. A straightforward method to prevent the under-estimated problem of aspartimide formation during chemical ligation-mediated protein synthesis. 2024. ⟨hal-04797697⟩

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