Organisation: Dpt Molecular, Structural and Chemical Biology

BERTRAND Marylène

email : marylene.bertrand[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.76.60

Engineer in chemical analysis within the  thematic group “NMR of biomolecules“

 


44 documents

Article dans une revue26 documents

  • Marylène Bertrand, Frédéric Szeremeta, Nadège Hervouet-Coste, Vincent Sarou-Kanian, Céline Landon, et al.. An adult Drosophila glioma model to highlight metabolic dysfunctions and evaluate the role of the serotonin 5‐HT 7 receptor as a potential therapeutic target. FASEB Journal, 2023, 37 (11), ⟨10.1096/fj.202300783RR⟩. ⟨hal-04301912⟩
  • Marion Maravat, Marylène Bertrand, Céline Landon, Franck Fayon, Séverine Morisset-Lopez, et al.. Complementary Nuclear Magnetic Resonance-Based Metabolomics Approaches for Glioma Biomarker Identification in a Drosophila melanogaster Model. Journal of Proteome Research, 2021, 20 (8), pp.3977-3991. ⟨10.1021/acs.jproteome.1c00304⟩. ⟨hal-03335927⟩
  • Marylène Bertrand, Martine Decoville, Herve Meudal, Serge Birman, Celine Landon. Metabolomic Nuclear Magnetic Resonance Studies at Presymptomatic and Symptomatic Stages of Huntington’s Disease on a Drosophila Model. Journal of Proteome Research, 2020, 19 (10), pp.4034-4045. ⟨10.1021/acs.jproteome.0c00335⟩. ⟨hal-02968233⟩
  • H Blasco, C Veyrat-Durebex, M Bertrand, F Patin, F Labarthe, et al.. A Multiplatform Metabolomics Approach to Characterize Plasma Levels of Phenylalanine and Tyrosine in Phenylketonuria.. JIMD reports, 2017, pp.69-79. ⟨10.1007/8904_2016_568⟩. ⟨hal-01622559⟩
  • Marylène Bertrand, Annie Chabin, Cyril Colas, Martine Cadène, Didier Chaput, et al.. The AMINO experiment: exposure of amino acids in the EXPOSE-R experiment on the International Space Station and in laboratory. International Journal of Astrobiology, 2015, 14 (01), pp.89-97. ⟨10.1017/S1473550414000354⟩. ⟨hal-01170486⟩
  • Hervé Cottin, K. Saiagh, Y.Y. Guan, M. Cloix, D. Khalaf, et al.. The AMINO experiment: a laboratory for astrochemistry and astrobiology on the EXPOSE-R facility of the International Space Station. International Journal of Astrobiology, 2015, 14 (01), pp.67-77. ⟨10.1017/S1473550414000500⟩. ⟨hal-01107510⟩
  • R. Demets, M. Bertrand, A. Bolkhovitinov, K. Bryson, C. Colas, et al.. Window contamination on Expose-R. International Journal of Astrobiology, 2015, 14 (1), pp.33-45. ⟨10.1017/S1473550414000536⟩. ⟨hal-04270210⟩
  • Frances Westall, Frédéric Foucher, Nicolas Bost, Marylène Bertrand, Damien Loizeau, et al.. Biosignatures on Mars: What, Where, and How? Implications for the Search for Martian Life. Astrobiology, 2015, 15 (11), pp.998-1029. ⟨10.1089/ast.2015.1374⟩. ⟨insu-01234353⟩
  • Hervé Cottin, Kafila Saiagh, D. Nguyen, Noël Grand, Yves Bénilan, et al.. Photochemical studies in low Earth orbit for organic compounds related to small bodies, Titan and Mars. Current and future facilities.. Bulletin de la Société Royale des Sciences de Liège, 2015, 84, pp.60 - 73. ⟨hal-01110518⟩
  • Francès Westall, Damien Loizeau, Frédéric Foucher, Nicolas Bost, Marylène Bertrand, et al.. Habitability on Mars from a Microbial Point of View. Astrobiology, 2013, 13 (9), pp.887-897. ⟨10.1089/ast.2013.1000⟩. ⟨insu-00866015⟩
  • Marylène Bertrand, Annie Chabin, André Brack, H. Cottin, D. Chaput, et al.. The PROCESS Experiment: Exposure of Amino Acids in the EXPOSE-E Experiment on the International Space Station and in Laboratory Simulations.. Astrobiology, 2012, 12 (5), pp.426-35. ⟨10.1089/ast.2011.0755⟩. ⟨hal-00721777⟩
  • Hervé Cottin, Yuan Yong Guan, Audrey Noblet, Olivier Poch, Kafila Saiagh, et al.. The PROCESS Experiment: An Astrochemistry Laboratory for Solid and Gaseous Organic Samples in Low-Earth Orbit. Astrobiology, 2012, 12 (5), pp.412-425. ⟨10.1089/ast.2011.0773⟩. ⟨hal-00710533⟩
  • Pierre de Marcellus, Marylène Bertrand, Michel Nuevo, Frances Westall, Louis Le Sergeant D’hendecourt. Prebiotic significance of extraterrestrial ice photochemistry: detection of hydantoin in organic residues.. Astrobiology, 2011, 11 (9), pp.847-54. ⟨10.1089/ast.2011.0677⟩. ⟨hal-00720601⟩
  • Marylène Bertrand, Sjerry van Der Gaast, Faith Vilas, Friedrich Hoerz, Gerald Haynes, et al.. The Fate of Amino Acids During Simulated Meteoritic Impact. Astrobiology, 2009, 9 (10), pp.943-951. ⟨10.1089/ast.2008.0327⟩. ⟨hal-00521727⟩
  • Marylène Bertrand, Sjerry van Der Gaast, Faith Vilas, Friedrich Hörz, Gerald Haynes, et al.. Effect of impact shock simulation on amino acids. Origins of Life and Evolution of Biospheres, 2009, 393, pp.52-53. ⟨hal-00527525⟩
  • Annie Chabin, Marylène Bertrand, André Brack, H. Cottin, Frances Westall. Exposure of Amino Acids on the International Space Station: EXPOSE-Eutef and EXPOSE-R. Origins of Life and Evolution of Biospheres, 2009, 39 (3-4 Sp. Iss. SI), pp.352-353. ⟨hal-00521873⟩
  • Marylène Bertrand, Annie Chabin, André Brack, Frances Westall. Separation of amino acid enantiomers via chiral derivatization and non chiral column by gas chromatography. Journal of Chromatography A, 2008, 1180 (1-2), pp.131-137. ⟨10.1016/j.chroma.2007.12.004⟩. ⟨hal-00282553⟩
  • Hervé Cottin, Patrice Coll, David Coscia, Nicolas Fray, Yuan Yong Guan, et al.. Heterogeneous solid/gas chemistry of organic compounds related to comets, meteorites, Titan and Mars: laboratory and in lower Earth orbit experiments. Advances in Space Research, 2008, 42 (12), pp.2019-2035. ⟨10.1016/j.asr.2007.09.017⟩. ⟨hal-00339783⟩
  • C. Buré, O. Boujard, M. Bertrand, C. Lange, A.F. Delmas. Letter: Collision-induced dissociation of peptide thioesters: influence of the peptide length on the fragmentation. European Journal of Mass Spectrometry, 2005, 11, pp.31-34. ⟨hal-00088531⟩
  • F. Boillot, A. Chabin, C. Buré, M. Venet, A. Belsky, et al.. The PERSEUS-Exobiology experiment on board MIR. Origins of Life and Evolution of the Biosphere, 2002, 32 (4), pp.359-385. ⟨10.1023/A:1020501226958⟩. ⟨hal-02104813⟩
  • Marylène Bertrand, André Brack. Conformational Transition of Acidic Peptides Exposed to Minerals in Suspension. Chemistry - A European Journal, 2000, 6 (18), pp.3452-3455. 3.0.CO;2-T">⟨10.1002/1521-3765(20000915)6:18<3452::AID-CHEM3452>3.0.CO;2-T⟩. ⟨hal-02106710⟩
  • Bernard Barbier, Marylène Bertrand, François Boillot, Annie Chabin, Didier Chaput, et al.. Delivery of extraterrestrial amino acids to the primitive Earth. Exposure experiments in Earth orbit.. Biological Sciences in Space, 1998, 12 (2), pp.92-95. ⟨10.2187/bss.12.92⟩. ⟨hal-02106435⟩
  • Marylène Bertrand, André Brack. Preferential beta-sheet structuration of multiconformational poly(Glu-Leu) by metallic ions. Letters in Peptide Science, 1997, 4 (4/6), pp.387-389. ⟨10.1023/A:1008877728409⟩. ⟨hal-02104833⟩
  • Marylène Bertrand, Denise Sy, André Brack. Salt-dependent conformational diversity of alternating poly (Glu-Leu). The Journal of Peptide Research, 1996, 49 (3), pp.269-272. ⟨10.1111/j.1399-3011.1997.tb00886.x⟩. ⟨hal-02104850⟩
  • Marylène Bertrand, A. Brack. Conformational variety of polyanionic peptides at low salt concentrations.. Origins of Life and Evolution of Biospheres, 1996, 27 (5-6), pp.585-95. ⟨hal-02104860⟩
  • Josette Verhaeghe, Eric Lacassie, Marylène Bertrand, Yves Trudelle. A new route to sequential polypeptides combining solid phase synthesis and solution peptide synthesis. Tetrahedron Letters, 1992, 34 (3), pp.461-464. ⟨10.1016/0040-4039(93)85102-3⟩. ⟨hal-02104862⟩

Communication dans un congrès2 documents

  • Marylène Bertrand, H. Meudal, S. Birman, M. Decoville, C. Landon. Metabolomic NMR studies & Huntington’s disease: models in transgenic drosophila. Conférence SMMAP 2017 - Conférence de Spectrométrie de Masse, Métabolomique et Fluxomique & Electrophorèse et Analyse Protéomique, Oct 2017, Marne-la-Vallée, France. ⟨hal-02919162⟩
  • H. Cottin, Y. Y. Guan, Patrice Coll, David Coscia, N. Fray, et al.. Astrochemistry on the EXPOSE/ISS and BIOPAN/Foton experiments. Highlights of Astronomy H15, Proceedings of the International Astronomical Union, XXVIIth IAU General Assembly, 2009, Rio de Janeiro, Brazil. pp.384-385, ⟨10.1017/S174392131001094X⟩. ⟨hal-00531605⟩

Poster14 documents

  • David Gosset, Julien Sobilo, Herve Meudal, Frederic Szeremeta, Marylène Bertrand, et al.. Plateforme MO2VING: from MOlecular Organization to in Vivo ImagiNG. 34ème Colloque Biotechnocentre, Oct 2022, Nouan Le Fuzelier, France. ⟨hal-03863246⟩
  • Marylène Bertrand, Vidian De Concini, Rania Boussad, Céline Landon, Arnaud Menuet. NMR metabolomic analysis: an aid to understanding neuroinflammatory processes in nociceptive defects of Fmr1 KO mice, model of Fragile X syndrome. 14es journées scientifiques RFMF, Nov 2021, Aussois, France. ⟨hal-03616628⟩
  • Marion Maravat, Marylène Bertrand, M. Decoville, C. Landon, Séverine Morisset-Lopez, et al.. Biomarkers involved in glioma development in Drosophila melanogaster model. European RFMF Metabomeeting 2020, Jan 2020, Toulouse, France. ⟨hal-02919170⟩
  • Marion Maravat, Marylène Bertrand, S. Morisset-Lopez, F. Fayon, V. Sarou-Kanian, et al.. Identification de biomarqueurs impliqués dans le développement de gliomes dans un modèle développé chez la drosophile. 13es Journées Canceropôle Grand-Ouest, Jul 2019, Tours, France. ⟨hal-02919893⟩
  • Marion Maravat, Martine Decoville, Marylène Bertrand, Celine Landon, Séverine Morisset-Lopez, et al.. NMR-based metabolomics for glioma biomarker discovery in a Drosophila melanogaster model. 3rd edition Metabolism & Cancer, Apr 2019, Marseille, France. ⟨hal-02986792⟩
  • Marylène Bertrand, M. Decoville, H. Meudal, S. Birman, C. Landon. Metabolomic NMR studies at presymptomatic and symptomatic stages of Huntington’s disease, on drosophila model. 20th annual meeting of Invertebrate Neurobiology, May 2019, Orléans, France. ⟨hal-02919877⟩
  • Marion Maravat, Marylène Bertrand, M. Decoville, C. Landon, F. Fayon, et al.. Biomarkers involved in glioma development in Drosophila melanogaster model. 12es journées scientifiques du Réseau Francophone de Métabolomique et de Fluxomique, May 2019, Clermont-Ferrand, France. ⟨hal-02919890⟩
  • Marylène Bertrand, M. Decoville, H. Meudal, S. Birman, C. Landon. Metabolomic NMR studies at presymptomatic and symptomatic stages of Huntington’s disease, on drosophila model. 12es journées scientifiques du Réseau Francophone de Métabolomique et de Fluxomique, May 2019, Clermont-Ferrand, France. ⟨hal-02919883⟩
  • Marylène Bertrand, M. Decoville, H. Meudal, S. Birman, C. Landon. Huntington’s disease: metabolomic studies by NMR analyzes on Drosophila Model. 11es Journées du Réseau francophone de métabolomique et de fluxomique, May 2018, Liège, Belgium. ⟨hal-02919911⟩
  • Marylène Bertrand, M. Decoville, H. Meudal, S. Birman, C. Landon. NMR metabolimics to detect Huntington’s disease at early stage. 28th ICMRBS - International Council on Magnetic Resonance in Biological Systems, Aug 2018, Dublin, Ireland. ⟨hal-02919924⟩
  • Marylène Bertrand, H. Meudal, M. Decoville, C. Landon. Prediction of Huntingon's Disease by Metabolomic NMR Analyzes: Studies in Drosophila Model. NMR: a tool for biology Xth, Jan 2017, Paris, France. ⟨hal-02919990⟩
  • Marylène Bertrand, Hervé Meudal, Florence Bordères, Vincent Furstoss, Louis Wozniak, et al.. Etude de la fertilité chez le bouc : analyse métabolomique par RMN. 10. Journées scientifiques du Réseau Francophone de Métabolomique et Fluxomique RFMF 2016, May 2016, Montpellier, France. 155 p., 2016, 10 JS Réseau Francophone de Métabolique et Fluxomique. ⟨hal-01581541⟩
  • H. Meudal, Marylène Bertrand, Laurence Jouvensal, A.F. Delmas, Françoise Paquet, et al.. La résonance Magnétique Nucléaire pour la chimie et la biologie. 29e colloque Biotechnocentre, Oct 2016, Seillac, France. ⟨hal-02920143⟩
  • Marylène Bertrand, H. Meudal, M. Decoville, C. Landon. La RMN, un outil pour la métabolomique. 29e colloque Biotechnocentre, Oct 2016, Seillac, France. ⟨hal-02453360⟩

Chapitre d'ouvrage1 document

  • Marylène Bertrand, Corinne Buré, Fabrice Fleury, André Brack. Prebiotic polymerization of amino acid thioesters on mineral surfaces. Geochemistry and the Origin of Life, Universal Academy Press, 2002. ⟨hal-03616744⟩

Rapport1 document

  • Balan Lavinia, Marylène Bertrand, Roberta Bongiovanni, Catherine Debiemme-Chouvy, Marie-Hélène Delville, et al.. Rapport de Prospective 2023 du Conseil Scientifique de l'Institut de Chimie du CNRS (Mandature 2019-2023). Centre national de la recherche scientifique (CNRS). 2023. ⟨hal-04307872v2⟩

Documents récupérés de l'archive ouverte HAL logo

BÉNÉDETTI Hélène

email : helene.benedetti[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.55.84

Research director, CBM Deputy scientific director, co-coordinator of the Department “Cell biology, Molecular Targets and innovative therapies” and co-responsible of the Team “Cell signalling and neurofibromatosis”

 


126 documents

Article dans une revue67 documents

  • Mohammed Bergoug, Christine Mosrin-Huaman, Amandine Serrano, Fabienne Godin, Michel Doudeau, et al.. An Atypical Mechanism of SUMOylation of Neurofibromin SecPH Domain Provides New Insights into SUMOylation Site Selection. Journal of Molecular Biology, 2024, 436 (22), pp.168768. ⟨10.1016/j.jmb.2024.168768⟩. ⟨hal-04771131⟩
  • Anthony Champiré, Rayan Berabez, Abdennour Braka, Aurélie Cosson, Justine Corret, et al.. Tetrahydropyridine LIMK inhibitors: Structure activity studies and biological characterization. European Journal of Medicinal Chemistry, 2024, 271, pp.116391-116391. ⟨10.1016/j.ejmech.2024.116391⟩. ⟨hal-04575964⟩
  • Hélène Bénédetti, Béatrice Vallée. LIM Kinases: From Molecular to Pathological Features. Cells, 2023, 12 (12), pp.1649. ⟨10.3390/cells12121649⟩. ⟨hal-04208415⟩
  • Elodie Villalonga, Christine Mosrin, Thierry Normand, Caroline Girardin, Amandine Serrano, et al.. LIM Kinases, LIMK1 and LIMK2, Are Crucial Node Actors of the Cell Fate: Molecular to Pathological Features. Cells, 2023, 12 (5), pp.805. ⟨10.3390/cells12050805⟩. ⟨hal-04208405⟩
  • Bojan Žunar, Christine Mosrin-Huaman, Hélène Bénédetti, Béatrice Vallée. Re-engineering of CUP1 promoter and Cup2/Ace1 transactivator to convert Saccharomyces cerevisiae into a whole-cell eukaryotic biosensor capable of detecting 10 nM of bioavailable copper. Biosensors and Bioelectronics, 2022, 214, pp.114502. ⟨10.1016/j.bios.2022.114502⟩. ⟨hal-03820214⟩
  • Rayan Berabez, Sylvain Routier, Hélène Bénédetti, Karen Plé, Béatrice Vallée. LIM kinases, promising but reluctant therapeutic targets: chemistry and preclinical validation in vivo. Cells, 2022, 11 (13), pp.2090. ⟨10.3390/cells11132090⟩. ⟨hal-03721458⟩
  • Wissem Deraredj Nadim, Shalina Hassanaly, Hélène Bénédetti, Claudine Kieda, Catherine Grillon, et al.. The GTPase-activating protein-related domain of neurofibromin interacts with MC1R and regulates pigmentation-mediated signaling in human melanocytes. Biochemical and Biophysical Research Communications, 2021, 534, pp.758-764. ⟨10.1016/j.bbrc.2020.11.003⟩. ⟨hal-03007433⟩
  • Frédéric Buron, Nuno Rodrigues, Thibault Saurat, Marie-Aude Hiebel, Stéphane Bourg, et al.. Design, Synthesis and SAR in 2,4,7-Trisubstituted Pyrido[3,2-d]Pyrimidine Series as Novel PI3K/mTOR Inhibitors. Molecules, 2021, 26 (17), pp.5349. ⟨10.3390/molecules26175349⟩. ⟨hal-03348966⟩
  • Skander A Abboud, Hadji H., Michel Doudeau, Hélène Bénédetti, Vincent Aucagne. A straightforward methodology to overcome solubility challenges for N-terminal cysteinyl peptide segments used in native chemical ligation. Chemical Science, 2021, 12, pp.3194 - 3201. ⟨10.1039/d0sc06001a⟩. ⟨hal-03447239⟩
  • Mohammed Bergoug, Michel Doudeau, Fabienne Godin, Christine Mosrin-Huaman, Béatrice Vallée, et al.. Neurofibromin Structure, Functions and Regulation. Cells, 2020, 9, ⟨10.3390/cells9112365⟩. ⟨hal-03070759v2⟩
  • Julie Tastet, Hélène Cuberos, Béatrice Vallée, Annick Toutain, Martine Raynaud, et al.. LIMK2-1 is a Hominidae-Specific Isoform of LIMK2 Expressed in Central Nervous System and Associated with Intellectual Disability. Neuroscience, 2019, 399, pp.199-210. ⟨10.1016/j.neuroscience.2018.12.017⟩. ⟨hal-02067472⟩
  • Béatrice Vallée, Michel Doudeau, Fabienne Godin, Hélène Bénédetti. Characterization at the Molecular Level using Robust Biochemical Approaches of a New Kinase Protein. Journal of visualized experiments : JoVE, 2019, 148, pp.e59820. ⟨10.3791/59820⟩. ⟨hal-02282630⟩
  • Béatrice Vallée, Hélène Cuberos, Michel Doudeau, Fabienne Godin, David Gosset, et al.. LIMK2-1, a new isoform of human LIMK2, regulates actin cytoskeleton remodeling via a different signaling pathway than that of its two homologs, LIMK2a and LIMK2b. Biochemical Journal, 2018, 475 (23), pp.3745-3761. ⟨hal-01966439⟩
  • Viorel Simion, Wissem Deraredj Nadim, Hélène Bénédetti, Chantal Pichon, Séverine Morisset-Lopez, et al.. Pharmacomodulation of microRNA Expression in Neurocognitive Diseases: Obstacles and Future Opportunities. Current Neuropharmacology, 2017, 15 (2), pp.276 - 290. ⟨10.2174/1570159X14666160630210422⟩. ⟨hal-01618771⟩
  • Wissem Deraredj Nadim, Simion Viorel, Hélène Bénédetti, Chantal Pichon, Patrick Baril, et al.. MicroRNAs in Neurocognitive Dysfunctions: New Molecular Targets for Pharmacological Treatments?. Current Neuropharmacology, 2017, 15 (2), pp.260 - 275. ⟨10.2174/1570159X14666160709001441⟩. ⟨hal-01618199⟩
  • Wissem Deraredj Nadim, Séverine Chaumont-Dubel, Fahima Madouri, Laetitia Cobret, Marie-Ludivine de Tauzia, et al.. Physical interaction between neurofibromin and serotonin 5-HT 6 receptor promotes receptor constitutive activity. Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (43), pp.12310 - 12315. ⟨10.1073/pnas.1600914113⟩. ⟨hal-01407899⟩
  • Julie Tastet, Loïc Decalonne, Sylviane Marouillat, Joëlle Malvy, Rose-Anne Thépault, et al.. Mutation screening of the ubiquitin ligase gene RNF135 in French patients with autism. Psychiatric Genetics, 2015, 25 (6), pp.263-267. ⟨10.1097/ypg.0000000000000100⟩. ⟨hal-02072312⟩
  • L Cobret, M L de Tauzia, J Ferent, E Traiffort, I Hénaoui, et al.. Targeting the cis-dimerization of LINGO-1 with low MW compounds affects its downstream signalling. British Journal of Clinical Pharmacology, 2015, 172 (3), pp.841-856. ⟨10.1111/bph.12945⟩. ⟨hal-01170735⟩
  • H. Cuberos, B. Vallée, P. Vourc'H, J. Tastet, C.R. Andres, et al.. Roles of LIM kinases in central nervous system function and dysfunction. FEBS Letters, 2015, 589 (24PartB), pp.3795-3806. ⟨10.1016/j.febslet.2015.10.032⟩. ⟨hal-02072231⟩
  • Solene Guiheneuf, Ludovic Paquin, Francois Carreaux, Emilie Durieu, Helene Benedetti, et al.. Microwave Assisted Organic Synthesis (MAOS) of New Dispacamide A Derivatives Bearing a Thiazolinone Platform, Biological Assays on Inhibition of Protein Kinases and Cell Effects. Current microwave chemistry, 2014, 1 (1), pp.33-40. ⟨10.2174/22133356114019990002⟩. ⟨hal-01114583⟩
  • Reine Nehmé, Hala Nehmé, Thibault Saurat, Marie-Ludivine De-Tauzia, Frédéric Buron, et al.. New in-capillary electrophoretic kinase assays to evaluate inhibitors of the PI3k/Akt/mTOR signaling pathway. Analytical and Bioanalytical Chemistry, 2014, 406 (15), pp.3743-3754. ⟨10.1007/s00216-014-7790-z⟩. ⟨hal-01180770⟩
  • Amélie Bruel, Romain Beneteau, Mylène Chabanne, Olivier Lozach, Rémy Le Guevel, et al.. Synthesis of new pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs as DYRK1A inhibitors. Bioorganic and Medicinal Chemistry Letters, 2014, 24 (21), pp.5037 - 5040. ⟨10.1016/j.bmcl.2014.09.017⟩. ⟨hal-01086026⟩
  • Thibault Saurat, Frédéric Buron, Nuno Rodrigues, Marie-Ludivine de Tauzia, Lionel Colliandre, et al.. Design, Synthesis, and Biological Activity of Pyridopyrimidine Scaffolds as Novel PI3K/mTOR Dual Inhibitors. Journal of Medicinal Chemistry, 2014, 57 (3), pp.613-631. ⟨10.1021/jm401138v⟩. ⟨hal-01180887⟩
  • François Hericourt, François Chefdor, Lucie Bertheau, Mirai Tanigawa, Tatsuya Maeda, et al.. Characterization of histidine-aspartate kinase HK1 and identification of histidine phosphotransfer proteins as potential partners in a Populus multistep phosphorelay. Physiologia Plantarum, 2013, 149 (2), pp.188-199. ⟨10.1111/ppl.12024⟩. ⟨hal-02070851⟩
  • Fabienne Godin, Sandrine Villette, Béatrice Vallée, Michel Doudeau, Séverine Morisset-Lopez, et al.. A fraction of neurofibromin interacts with PML bodies in the nucleus of the CCF astrocytoma cell line.. Biochemical and Biophysical Research Communications, 2012, 418 (4), pp.689-94. ⟨10.1016/j.bbrc.2012.01.079⟩. ⟨hal-00721861⟩
  • Béatrice Vallée, Michel Doudeau, Fabienne Godin, Aurélie Gombault, Aurélie Tchalikian-Cosson, et al.. Nf1 RasGAP Inhibition of LIMK2 Mediates a New Cross-Talk between Ras and Rho Pathways. PLoS ONE, 2012, 7 (10), pp.e47283. ⟨10.1371/journal.pone.0047283⟩. ⟨hal-03054185⟩
  • Dominique Arnaud, Annabelle Déjardin, Jean-Charles Leplé, Marie-Claude Lesage-Descauses, Nathalie Boizot, et al.. Expression analysis of LIM gene family in poplar, toward an updated phylogenetic classification.. BMC Research Notes, 2012, 5, pp.102. ⟨10.1186/1756-0500-5-102⟩. ⟨hal-00721759⟩
  • A. Bruel, Cedric Logé, M.-L. de Tauzia, M. Ravache, Ronan Le Guével, et al.. Synthesis and biological evaluation of new 5-benzylated 4-oxo-3,4-dihydro-5Hpyridazino[4,5-b]indoles as PI3Ka inhibitors.. European Journal of Medicinal Chemistry, 2012, 57, pp.225-233. ⟨hal-00764872⟩
  • Martine Beaufour, Fabienne Godin, Béatrice Vallée, Martine Cadene, Hélène Bénédetti. Interaction Proteomics Suggests a New Role for the Tfs1 Protein in Yeast.. Journal of Proteome Research, 2012, 11 (6), pp.3211-3218. ⟨10.1021/pr201239t⟩. ⟨hal-00721771⟩
  • Julie Tastet, Patrick Vourc'H, Frédéric Laumonnier, Béatrice Vallée, Carole Michelle, et al.. LIMK2d, a truncated isoform of Lim kinase 2 regulates neurite growth in absence of the LIM kinase domain. Biochemical and Biophysical Research Communications, 2012, 420 (2), pp.247-252. ⟨10.1016/j.bbrc.2012.02.134⟩. ⟨hal-01136281⟩
  • Aurélie Gombault, Jonas Warringer, Robert Caesar, Fabienne Godin, Béatrice Vallée, et al.. A phenotypic study of TFS1 mutants differentially altered in the inhibition of Ira2p or CPY. FEMS Yeast Research, 2009, 9 (6), pp.867-874. ⟨10.1111/j.1567-1364.2009.00535.x⟩. ⟨hal-00522432⟩
  • Aurélie Gombault, Fabienne Godin, Denise Sy, Baptiste Legrand, Hélène Chautard, et al.. Molecular Basis of the Tfs1/Ira2 Interaction: A Combined Protein Engineering and Molecular Modelling Study. Journal of Molecular Biology, 2007, 374 (3), pp.604-617. ⟨10.1016/j.jmb.2007.09.057⟩. ⟨hal-00181161⟩
  • F. Chefdor, H. Bénédetti, C. Depierreux, Franck Delmotte, D. Morabito, et al.. Osmotic stress sensing in Populus: components identification of a phosphorelay system. FEBS Letters, 2006, 580 (1), pp.77-81. ⟨10.1016/j.febslet.2005.11.051⟩. ⟨hal-00088838⟩
  • S. Quevillon-Cheruel, N. Leulliot, M. Graille, N. Hervouet, F. Coste, et al.. Crystal structure of yeast YHR049W/FSH1, a member of the serine hydrolase family. Protein science : a publication of the Protein Society., 2005, 14, pp.1350-1356. ⟨hal-00088667⟩
  • H. Chautard, M. Jacquer, F. Schoentgen, N. Bureaud, H. Bénédetti. Tfs1, a member of the PEBP family, inhibits the Ira2p but not the Ira1p Ras GTPase activating protein in Saccharomyces cerevisiae. Eukaryotic Cell, 2004, 3 (2), pp.459-470. ⟨10.1128/EC.3.2.459-470.2004⟩. ⟨hal-00112967⟩
  • S. Castella, Hélène Bénédetti, R. de Llorens, J.L. Dacheux, F. Dacheux. Train A, an RNase-A-like protein without RNase activity is secreted and reabsorbed by the same epididymal cells under testicular control. Biology of Reproduction, 2004, 71 (5), pp.1677-1687. ⟨10.1095/biolreprod.104.031666⟩. ⟨hal-00112960⟩
  • Emmanuelle Bouveret, Laure Journet, Anne Walburger, E. Cascales, Hélène Bénédetti, et al.. Analysis of the Escherichia coli Tol-Pal and TonB systems by periplasmic production of Tol, TonB, colicin, or phage capsid soluble domains.. Biochimie, 2002, 84 (5-6), pp.413-21. ⟨hal-02130103⟩
  • Laurence Serre, F Serre, Charles Zelwer, Nicole Bureaud, Francoise Schoentgen, et al.. Crystal structures of YBHB and YBCL from Escherichia coli , two bacterial homologues to a Raf kinase inhibitor protein 1 1Edited by R. Huber. Journal of Molecular Biology, 2001, 310 (3), pp.617-634. ⟨10.1006/jmbi.2001.4784⟩. ⟨hal-02130120⟩
  • Laure Journet, E. Bouveret, A. Rigal, R Lloubes, C Lazdunski, et al.. Import of colicins across the outer membrane of Escherichia coli involves multiple protein interactions in the periplasm.. Molecular Microbiology, 2001, 42 (2), pp.331-44. ⟨hal-02130124⟩
  • C. Lazdunski, E. Bouveret, A Rigal, Laure Journet, R. Lloubes, et al.. Colicin import into Escherichia coli cells requires the proximity of the inner and outer membranes and other factors. International Journal of Medical Microbiology, 2000, 290 (4-5), pp.337-344. ⟨10.1016/S1438-4221(00)80037-5⟩. ⟨hal-02130686⟩
  • Chantal Abergel, E. Bouveret, J.M Claverie, K Brown, A Rigal, et al.. Structure of the Escherichia coli TolB protein determined by MAD methods at 1.95 A resolution.. Structure, 1999, 7 (10), pp.1291-300. ⟨hal-02130130⟩
  • Laure Journet, A Rigal, C Lazdunski, H Bénédetti. Role of TolR N-terminal, central, and C-terminal domains in dimerization and interaction with TolA and tolQ.. Journal of Bacteriology, 1999, 181 (15), pp.4476-84. ⟨hal-02130149⟩
  • E Bouveret, H Bénédetti, A Rigal, E. Loret, C Lazdunski. In vitro characterization of peptidoglycan-associated lipoprotein (PAL)-peptidoglycan and PAL-TolB interactions.. Journal of Bacteriology, 1999, 181 (20), pp.6306-11. ⟨hal-02130134⟩
  • C.J Lazdunski, E. Bouveret, A. Rigal, Laure Journet, R Lloubès, et al.. Colicin import into Escherichia coli cells.. Journal of Bacteriology, 1998, 180 (19), pp.4993-5002. ⟨hal-02130152⟩
  • E Bouveret, A Rigal, C Lazdunski, H Bénédetti. Distinct regions of the colicin A translocation domain are involved in the interaction with TolA and TolB proteins upon import into Escherichia coli.. Molecular Microbiology, 1998, 27 (1), pp.143-57. ⟨hal-02130155⟩
  • Chantal Abergel, A Rigal, S Chenivesse, C Lazdunski, J.M Claverie, et al.. Crystallization and preliminary crystallographic study of a component of the Escherichia coli tol system: TolB.. Acta crystallographica Section D : Structural biology [1993-..], 1998, 54 (Pt 1), pp.102-4. ⟨hal-02130160⟩
  • A Rigal, E. Bouveret, R Lloubes, C Lazdunski, H Bénédetti. The TolB protein interacts with the porins of Escherichia coli.. Journal of Bacteriology, 1997, 179 (23), pp.7274-7279. ⟨10.1128/jb.179.23.7274-7279.1997⟩. ⟨hal-02130169⟩
  • E Bouveret, A Rigal, C Lazdunski, H Bénédetti. The N-terminal domain of colicin E3 interacts with TolB which is involved in the colicin translocation step.. Molecular Microbiology, 1997, 23 (5), pp.909-20. ⟨hal-02130173⟩
  • R Derouiche, M Gavioli, H Bénédetti, A Prilipov, C Lazdunski, et al.. TolA central domain interacts with Escherichia coli porins.. EMBO Journal, 1996, 15 (23), pp.6408-15. ⟨hal-02130175⟩
  • E. Bouveret, R Derouiche, R. Rigal, R Lloubès, C Lazdunski, et al.. Peptidoglycan-associated lipoprotein-TolB interaction. A possible key to explaining the formation of contact sites between the inner and outer membranes of Escherichia coli. Journal of Biological Chemistry, 1995, 270 (19), pp.11071-11077. ⟨10.1074/jbc.270.19.11071⟩. ⟨hal-02130195⟩
  • R Derouiche, H Bénédetti, Jc Lazzaroni, C Lazdunski, R Lloubès. Protein complex within Escherichia coli inner membrane. TolA N-terminal domain interacts with TolQ and TolR proteins. Journal of Biological Chemistry, 1995, 270 (19), pp.11078-11084. ⟨10.1074/jbc.270.19.11078⟩. ⟨hal-02130187⟩
  • Denis Duché, L. Letellier, V Géli, H Bénédetti, D. Baty. Quantification of group A colicin import sites.. Journal of Bacteriology, 1995, 177 (17), pp.4935-4939. ⟨10.1128/jb.177.17.4935-4939.1995⟩. ⟨hal-02130183⟩
  • Jean Claude Lazzaroni, Anne Vianney, V Vianney, Jean Luc Popot, Hélène Bénédetti, et al.. Transmembrane α-Helix Interactions are Required for the Functional Assembly of theEscherichia coliTol Complex. Journal of Molecular Biology, 1995, 246 (1), pp.1-7. ⟨10.1006/jmbi.1994.0058⟩. ⟨hal-02130202⟩
  • Denis Duché, L. Letellier, V. Geli, H. Bénédetti, D. Baty. Quantification of group A colicin import sites.. Journal of Bacteriology, 1995, 177 (17), pp.4935-4939. ⟨10.1128/jb.177.17.4935-4939.1995⟩. ⟨hal-02440962⟩
  • G. Guihard, P. Boulanger, H Bénédetti, R Lloubés, M Besnard, et al.. Colicin A and the Tol proteins involved in its translocation are preferentially located in the contact sites between the inner and outer membranes of Escherichia coli cells.. Journal of Biological Chemistry, 1994, 269 (8), pp.5874-80. ⟨hal-02130218⟩
  • David Espesset, Yves Corda, Kyle Cunningham, Hélène Bénédetti, Roland Lloubes, et al.. The colicin A pore-forming domain fused to mitochondrial intermembrane space sorting signals can be functionally inserted into the Escherichia coli plasma membrane by a mechanism that bypasses the Tol proteins. Molecular Microbiology, 1994, 13 (6), pp.1121-1131. ⟨10.1111/j.1365-2958.1994.tb00503.x⟩. ⟨hal-02130213⟩
  • H Bénédetti, S Raths, F Crausaz, H. Riezman. The END3 gene encodes a protein that is required for the internalization step of endocytosis and for actin cytoskeleton organization in yeast.. Molecular Biology of the Cell, 1994, 5 (9), pp.1023-37. ⟨hal-02130204⟩
  • J Rohrer, H Bénédetti, B Zanolari, H. Riezman. Identification of a novel sequence mediating regulated endocytosis of the G protein-coupled alpha-pheromone receptor in yeast.. Molecular Biology of the Cell, 1993, 4 (5), pp.511-21. ⟨hal-02130242⟩
  • V Geli, R Lloubes, S Zaat, R van Spaendonk, C Rollin, et al.. Recognition of the colicin A N-terminal epitope 1C11 in vitro and in vivo in Escherichia coli by its cognate monoclonal antibody. FEMS Microbiology Letters, 1993, 109 (2-3), pp.335-342. ⟨10.1016/0378-1097(93)90042-z⟩. ⟨hal-02130222⟩
  • G. Guihard, H Bénédetti, M Besnard, L. Letellier. Phosphate efflux through the channels formed by colicins and phage T5 in Escherichia coli cells is responsible for the fall in cytoplasmic ATP.. Journal of Biological Chemistry, 1993, 268 (24), pp.17775-80. ⟨hal-02130233⟩
  • Hélène Bénédetti, R Lloubès, C Lazdunski, L. Letellier. Colicin A unfolds during its translocation in Escherichia coli cells and spans the whole cell envelope when its pore has formed.. EMBO Journal, 1992, 11 (2), pp.441-7. ⟨hal-02130272⟩
  • Hélène Bénédetti, C Lazdunski, R Lloubès. Protein import into Escherichia coli: colicins A and E1 interact with a component of their translocation system.. EMBO Journal, 1991, 10 (8), pp.1989-95. ⟨hal-02130277⟩
  • M Frenette, H Bénédetti, A. Bernadac, D. Baty, C Lazdunski. Construction, expression and release of hybrid colicins.. Journal of Molecular Biology, 1991, 217 (3), pp.421-8. ⟨hal-02130287⟩
  • Hélène Bénédetti, M Frenette, D. Baty, M Knibiehler, F. Pattus, et al.. Individual domains of colicins confer specificity in colicin uptake, in pore-properties and in immunity requirement.. Journal of Molecular Biology, 1991, 217 (3), pp.429-39. ⟨hal-02130283⟩
  • C. Lazdunski, H Bénédetti. Insertion and translocation of proteins into and through membranes.. FEBS Letters, 1990, 268 (2), pp.408-14. ⟨hal-02130669⟩
  • D. Baty, F. Pattus, M. Parker, H. Bénédetti, M. Frenette, et al.. Uptake across the cell envelope and insertion into the inner membrane of ion channel-forming colicins in E coli. Biochimie, 1990, 72 (2-3), pp.123-130. ⟨10.1016/0300-9084(90)90137-6⟩. ⟨hal-02130296⟩
  • H. Bénédetti, M. Frenette, D. Baty, R Lloubès, V. Geli, et al.. Comparison of the Uptake Systems for the Entry of Various BtuB Group Colicins into Escherichia coli. Microbiology, 1989, 135 (12), pp.3413-3420. ⟨10.1099/00221287-135-12-3413⟩. ⟨hal-02130300⟩

Communication dans un congrès16 documents

  • Anthony Champiré, Margaux Sainjon, Abdennour Braka, Samia Aci-Seche, Pascal Bonnet, et al.. Synthesis and preclinical validation of LIMKs inhibitors: Promising drugs for osteosarcoma treatment?. XXVII EFMC International Symposium on Medicinal Chemistry, Sep 2022, NICE, France. ⟨hal-04823073⟩
  • Rayan Berabez, Anthony Champiré, Margaux Sainjon, Abdennour Braka, Samia Aci-Seche, et al.. Synthesis and preclinical validation of LIMKs inhibitors: Promising drugs for osteosarcoma treatment?. SCT 29th Young Research Fellow Meeting, Jul 2022, Nantes, France. ⟨hal-04822252⟩
  • Justine Corret, Sokaina Hammoud, Frédéric Buron, Pierre Daligaux, Christophe Chesné, et al.. Development of a bio­active fluorescent inhibitor probe targeting the Rho kinase ROCK for monitoring inhibition action. FEBS 2021, the 45th FEBS Congress, Jul 2021, Virtual, France. ⟨hal-03668584⟩
  • N Laroui, C Delehedde, C Goncalves, F Godin, Federico Perche, et al.. High Efficiency of Histidylated-based Lipid Formulations for mRNA Transfection of Human Schwann Cells. SFNano 2021, Dec 2021, Angers, France. ⟨hal-03668422⟩
  • Béatrice Vallée, Christine Mosrin-Huaman, Hélène Bénédetti, Régis Guégan, Bojan Zunar. Life in the bioink: Physiology and energetics of Saccharomyces cerevisiae embedded in polymerized Pluronic F127-DMA, a “smart” thermoresponsive hydrogel. ICY15 meets 30ICYGMB, The spirit of Yeast, Aug 2021, Vienne, virtual, Austria. ⟨hal-03559939⟩
  • Béatrice Vallée, Hélène Bénédetti. Séminaire invité : Signalisation cellulaire et Neurofibromatose. Journées NF, Sep 2021, Orléans, France. ⟨hal-03560050⟩
  • Béatrice Vallée, K. Plé, A. Cosson, M. Doudeau, F. Godin, et al.. Détermination et mise en œuvre d’un modèle in vivo pour tester de nouveaux inhibiteurs originaux des LIM kinases, cibles thérapeutiques émergentes dans le cancer. Cancéropôle Grand Ouest, Colloque du Réseau Molécules marines, métabolisme et cancer, May 2019, Mansigné, France. ⟨hal-02928507⟩
  • H. Bénédetti, Béatrice Vallée, A. Cosson, F. Godin, M. Doudeau. Les LIM kinases : nouvelles cibles thérapeutiques anti-cancer. Journée scientifique du réseau « Cancers hormonaux–dépendants » du Cancéropôle Grand-Ouest, Apr 2019, Nantes, France. ⟨hal-02928496⟩
  • M. Bergoug, A. Cosson, D. Casas, M. Doudeau, F. Godin, et al.. Neurofibromin, a new SUMO target involved in neurofibromatosis type 1 disease. 6th LIA Workshop on "Biomarkers and mediators of diseases and new approaches in repair/regenerative therapies, Jun 2019, Varsovie, Poland. ⟨hal-02928511⟩
  • Béatrice Vallée, S. Routier, A. Cosson, M. Doudeau, F. Godin, et al.. Développement de modulateurs des LIM kinases. Cancéropôle Grand Ouest - 14e colloque du Réseau Produits de la mer en cancérologie - 5e colloque du Réseau Canaux ioniques et cancer, May 2018, Mansigné, France. ⟨hal-02928559⟩
  • Béatrice Vallée, Karen Plé, A. Cosson, M. Doudeau, F. Godin, et al.. Développement de petites molécules inhibitrices des LIM kinases, nouvelles cibles thérapeutiques pour lutter contre le cancer, les maladies neurologiques et la neurofibromatose. Journée Fédération CBM-ICOA, Jan 2018, Orléans, France. ⟨hal-02928530⟩
  • M. Bergoug, A. Cosson, M. Doudeau, F. Godin, Béatrice Vallée, et al.. Study of the sumoylation of neurofibromin, the protein responsible for neurofibromatosis type 1. Joint Global Neurofibromatosis Conference 2018, Nov 2018, Paris, France. ⟨hal-02928220⟩
  • Béatrice Vallée, A. Cosson, M. Doudeau, F Godin, A. Braka, et al.. Neurofibromatosis type I: from basic to applied research. 4th LIA Workshop, Jun 2017, Cracovie, Poland. ⟨hal-02928517⟩
  • Béatrice Vallée, Hélène Bénédetti, F. Godin, M. Doudeau. Study of new partners of neurofibromin: an approach to identify novel therapeutic targets for neurofibromatosis type 1. 17th European Neurofibromatosis meeting, Sep 2016, Albano-Terme, Italy. ⟨hal-02928226⟩
  • Wassim Lakhal, Nathalie Boizot, Marie-Claude Lesage Descauses, Odile Rogier, Véronique Laine-Prade, et al.. Both ChIP-SEQ and in planta gene modification demonstrate the involvement of MYB090 and MYB156 in secondary cell wall formation in poplar. INUPRAG-Meeting 2015, Oct 2015, Nancy, France. ⟨hal-01604786⟩
  • J. Tastet, P. Vourc'H, F. Laumonnier, C. Michelle, Anne Duittoz, et al.. Expression des isoformes de LIM Kinase 2 pendant la neurogenèse et la stimulation des neurones. 22. Colloque Biotechnocentre, Oct 2009, Seillac, France. ⟨hal-02753426⟩

Poster32 documents

  • Mohammed Bergoug, Christine Mosrin-Huaman, Amandine Serrano, Fabienne Godin, Michel Doudeau, et al.. Characterization of a new Post Translational Modification of Neurofibromin: atypical structural requirements for its SUMOylation. 2024 Global NF Conference, Jun 2024, Brussels, Belgium. ⟨hal-03679991⟩
  • Mohammed Bergoug, Christine Mosrin-Huaman, Amandine Serrano, Fabienne Godin, Michel Doudeau, et al.. Characterization of a new Post Translational Modification of Neurofibromin: atypical structural requirements for its SUMOylation. 2024 Global NF Conference, Jun 2024, Brussels, Belgium. ⟨hal-04778711⟩
  • Hélène Bénédetti, Christine Mosrin-Huaman, Mohammed Bergoug, Amandine Serrano, Fabienne Godin, et al.. Deciphering the Molecular Mechanism of Pathogenicity in Destabilized variants of Neurofibromin mutated in its SecPH domain. 2024 Global NF Conference, Jun 2024, Brussels (Belgium), Belgium. ⟨hal-04779581⟩
  • Karen Plé, B. Vallée, R. Berabez, A. Champiré, M. Sainjon, et al.. Les LIM kinases, des cibles thérapeutiques prometteuses pour le traitement du glioblastome : de la conception de petites molécules inhibitrices aux tests cellulo. CCCancéropôle Grand Ouest, colloque du réseau Molécules marines, métabolisme et cancer, May 2023, Mansigné, France. ⟨hal-04556346⟩
  • N Laroui, C Delehedde, Cristine Gonçalves, F Godin, F Perche, et al.. High Efficiency of Histidylated-based Lipid Formulations for mRNA Transfection of Human Schwann Cells. 10th mRNA Health Conference, Nov 2021, Berlin, Germany. ⟨hal-03668434⟩
  • Elodie Villalonga, Célina Chalal, Déborah Cassas, Michel Doudeau, Fabienne Godin, et al.. New insights into the regulation of actin cytoskeleton dynamics via the Rho/ROCK/LIMK2/cofilin signalling pathway: a novel mechanism of regulation of cofilin by LIMK2. FEBS 2021, the 45th FEBS Congress, Jul 2021, Ljubljana, virtual, Slovenia. ⟨hal-03680139⟩
  • Christine Mosrin-Huaman, Mohammed Bergoug, Fabienne Godin, Michel Doudeau, Iva Sosic, et al.. Sumoylation of Neurofibromin and its SecPH Domain Plays a Role in Their Functions and Implies Unexpected Structural Requirements. 2021 NF1 virtual conference, Jun 2021, Virtual, France. ⟨hal-03680001⟩
  • Bojan Zunar, Christine Mosrin-Huaman, Hélène Bénédetti, Régis Guégan, Béatrice Vallée. Stressed by hydrogel? Physiological response of yeast cells embedded in thermoresponsive Pluronic F127: a prerequisite for bioreactor development. FEBS 2021, the 45th FEBS Congress, Jul 2021, Ljubljana, Slovenia. ⟨hal-03679975⟩
  • Justine Corret, Sokaina Hammoud, Frédéric Buron, Pierre Daligaux, Christophe Chesné, et al.. Development of a bio­active fluorescent inhibitor probe targeting the Rho kinase ROCK for monitoring inhibition action. FEBS 2021, the 45th FEBS Congress, Jul 2021, Lnubljana, virtual, Slovenia. ⟨hal-03679980⟩
  • Mélissa Thomas, Lauren Blot, Kevin Lesage, Fabienne Godin, Michel Doudeau, et al.. New molecular insights into the crosstalk between Rho/ROCK/LIMK2/cofilin signalling pathway and Nf1. 2021 NF1 virtual conference, Jun 2021, Virtual, France. ⟨hal-03679999⟩
  • Bojan Zunar, Christine Mosrin-Huaman, Hélène Bénédetti, Régis Guégan, Béatrice Vallée. Life in the bioink: Physiology and energetics of Saccharomyces cerevisiae embedded in polymerized Pluronic F127-DMA, a “smart” thermoresponsive hydrogel. ICY15 meets 30ICYGMB, The spirit of Yeast, Aug 2021, Vienne, virtual, Austria. ⟨hal-03679966⟩
  • H. Bénédetti, Béatrice Vallée, J. Tastet, H. Cubéros, A. Toutain, et al.. Molecular and functional characterization of LIMK2-1, a hominidae-specific isoform of LIMK2 associated with intellectual disability. NeuroFrance 2019, May 2019, Marseille, France. ⟨hal-02924881⟩
  • H. Bénédetti, M. Bergoug, I. Sošic, M. Doudeau, F. Godin, et al.. Study of the different forms of sumoylation of the neurofibromin SecPH domain. EMBO Workshop "The ubiquitin system: Biology, mechanisms and roles in disease", Sep 2019, Cavtat, Croatia. ⟨hal-02924090⟩
  • M. Bergoug, I. Sošic, M. Doudeau, F. Godin, Béatrice Vallée, et al.. Neurofibromin, a new SUMO target involved in neurofibromatosis type 1 disease. EMBO Workshop "The ubiquitin system: Biology, mechanisms and roles in disease", Sep 2019, Cavtat, Croatia. ⟨hal-02924095⟩
  • Béatrice Vallée, A. Cosson, M. Doudeau, F. Godin, A. Champiré, et al.. LIM kinases, new therapeutic targets to treat cancers, neurological disorders and Neurofibromatosis: development of small molecule inhibitors. FEBS Meeting 2019, Jul 2019, Cracovie, Poland. ⟨hal-02924140⟩
  • Christine Mosrin-Huaman, B. Handelaoui, H. Bénédetti, Béatrice Vallée. Yeast biosensors to detect environmental pollutants into effluent waters. ICYGMB XXIX International Congress on Yeast Genetics and Molecular Biology, Aug 2019, Göteborg, Sweden. ⟨hal-02924111⟩
  • Béatrice Vallée, A. Cosson, M. Doudeau, F. Godin, A. Champiré, et al.. Development of small molecule inhibitors of LIM kinases, new therapeutic targets to treat Neurofibromatosis type I. Joint Global Neurofibromatosis Conference 2018, Nov 2018, Paris, France. ⟨hal-02924077⟩
  • H. Bénédetti, M. Doudeau, F. Godin, Béatrice Vallée, A. Cosson, et al.. LARP6, a RNA−binding protein involved in translation and stability of collagen mRNA, is a new partner of Neurofibromin: Molecular studies and functional implications. Joint Global Neurofibromatosis Conference 2018, Nov 2018, Paris, France. ⟨hal-02924084⟩
  • M. Bergoug, A. Cosson, M. Doudeau, F. Godin, Béatrice Vallée, et al.. Study of the sumoylation of neurofibromin, the protein responsible for neurofibromatosis type 1. EMBO Conference "Ubiquitin and SUMO: from molecular mechanisms to system-wide responses, Sep 2017, Cavtat, Croatia. ⟨hal-02924070⟩
  • A. Champiré, A. Braka, Béatrice Vallée, M. Doudeau, F. Godin, et al.. Design, synthesis and biological evaluation of LIMK inhibitors. XXIVe Journées Jeunes Chercheurs (SCT), Feb 2017, Châtenay-Malabry, France. ⟨hal-02904837⟩
  • Séverine Morisset-Lopez, W. Deraredj Nadim, S. Chaumont−dubel, F. Madouri, L. Cobret, et al.. Neurofibromin 1 promotes constitutive activity of native 5−HT6 receptors expressed in mouse prefrontal cortex. Neurofrance, May 2017, Bordeaux, France. ⟨hal-02973767⟩
  • A. Champiré, A. Braka, B. Vallée, M. Doudeau, F. Godin, et al.. LIM kinases as new therapeutic targets for the treatment of neurofibromatosis type 1. VII International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC) –, Aug 2017, Vienne, Austria. ⟨hal-02904794⟩
  • Béatrice Vallée, A. Cosson, M. Doudeau, F. Godin, Anthony Champiré, et al.. LIM Kinases: new anticancer therapeutic targets. Breast Cancer Symposium, Jun 2017, Nantes, France. ⟨hal-03680148⟩
  • Béatrice Vallée, Hélène Cuberos, Julie Tastet, Michel Doudeau, Fabienne Godin, et al.. LIMK2-1, a new primate-specific isoform of LIMK2, is associated with intellectual disability. 10 th FENS (Forum of Neurosciences), Jul 2016, Copenhague, Denmark. . ⟨hal-02453486⟩
  • A. Champiré, A. Braka, Béatrice Vallée, M. Doudeau, F. Godin, et al.. Conception, synthèse et évaluation biologique d’inhibiteurs de LIM kinases. 29e colloque de Biotechnocentre, Oct 2016, Seillac, France. ⟨hal-02904847⟩
  • Béatrice Vallée, Michel Doudeau, F. Godin, H. Cubéros, A. Champiré, et al.. Projet Région LiCorNe: LIMK protein inhibitors, new therapeutic agents for treatment of cognitive disorders associated with type I Neurofibromatosis. Journée Fédération PCV FR2708, Jan 2016, Orléans, France. ⟨hal-02924056⟩
  • W. Deraredj Nadim, S. Chaumont-Dubel, F. Madouri, L. Cobret, M.-L. de Tauzia, et al.. A Physical Interaction between Neurofibromin and Serotonin 5-HT6 Receptor Promotes Receptor Constitutive Activity. 5th annual meeting of the GDR 3545 RCPG-PhysioMed 2016, Nov 2016, Tours, France. ⟨hal-02973912⟩
  • Annabelle Dejardin, Wassim Lakhal, Nathalie Boizot, Marie-Claude Lesage Descauses, Odile Rogier, et al.. Unraveling the function of MYB090 and MYB156 in secondary cell wall formation in poplar using both ChIP-SEQ and in planta gene modification approach. XIV Cell Wall Meeting, Jun 2016, Chania, Grèce. , 2016, XIV Cell Wall Meeting. Programme and Book of Abstracts. ⟨hal-02740921⟩
  • Béatrice Vallée, Michel Doudeau, Fabienne Godin, Anthony Champiré, Karen Plé, et al.. LIM kinases: new therapeutic targets to treat Neurofibromatosis type I. The 7th EMBO meeting, Sep 2016, Mannheim, Germany. . ⟨hal-02453490⟩
  • Hélène Bénédetti, Fabienne Godin, Michel Doudeau, Béatrice Vallée, Marie-Ludivine De Tauzia, et al.. LINGO-1, a protein involved in various neurodevelopmental processes, interacts with neurofibromin (Nf1), the protein responsible for neurofibromatosis type I: molecular studies and functional implications. 10 th FENS (Forum of Neuroscience), Jul 2016, Copenhague, Denmark. ⟨hal-02453487⟩
  • Béatrice Vallée, Hélène Cuberos, Michel Doudeau, Fabienne Godin, Patrick Vourc’h, et al.. The three isoforms of human LIMK2 regulate actin cytoskeleton remodeling via different pathways. EMBL Symposium, Actin in action: From Molecules to Cellular Functions, Sep 2016, Heidelberg, Germany. . ⟨hal-02453489⟩
  • J. Tastet, P. Vourc'H, F. Laumonnier, C. Michelle, Anne Duittoz, et al.. LIMK2 (LIM kinase2) isoforms are differentially expressed during neuronal differentiation. 7. FENS Forum of European Neuroscience, Jul 2010, Amsterdam, Netherlands. n.p., 2010. ⟨hal-02818145⟩

Chapitre d'ouvrage7 documents

  • Emmanuelle Bouveret, Claude Lazdunski, Hélène Bénédetti. The Tol/PAL and TonB systems : two envelope-spanning protein complexes involved in colicin import in E. coli.. Molecular Dynamics of Biomembranes, Springer Berlin Heidelberg, pp.59-69, 1996. ⟨hal-02130680⟩
  • H. Bénédetti, V. Geli. Colicin transport, channel formation and inhibition. Handbook of Biological Physics, pp.665-691, 1996. ⟨hal-02130677⟩
  • Vincent Géli, Hélène Bénédetti. Insertion of Proteins into Membranes A Survey. Membrane biogenesis, pp.21-69, 1994, Subcellular Biochemistry, 978-1-4613-6018-6. ⟨hal-02130265⟩
  • L. Letellier, C. Lazdunski, H. Bénédetti, J. Bourdineaud, P. Boulanger. In Vivo Properties of Colicin A: Channel Activity and Translocation. Bacteriocins, Microcins and Lantibiotics, Springer Berlin Heidelberg, pp.119-125, 1992. ⟨hal-02130671⟩
  • C. Lazdunski, D. Baty, V. Geli, R. Lloubes, H. Bénédetti, et al.. Molecular Mechanism of Action of Pore-Forming Colicins and of their Immunity Proteins. Membrane Proteins: Structures, Interactions and Models, pp.413-425, 1992. ⟨hal-02130675⟩
  • Hélène Bénédetti, Lucienne Letellier, Roland Lloubes, Vincent Géli, Daniel Baty, et al.. Import of Colicins into Escherichia Coli. Dynamics of Membrane Assembly, 63, Springer Berlin Heidelberg, pp.315-332, 1992. ⟨hal-02130670⟩
  • Hélène Bénédetti, Lucienne Letellier, Roland Lloubes, Vincent Géli, Daniel Baty, et al.. Study of the Import Mechanisms of Colicins Through Protein Engineering and K+ Efflux Kinetics. Bacteriocins, Microcins and Lantibiotics, Springer Berlin Heidelberg, pp.215-223, 1992. ⟨hal-02130674⟩

Brevet3 documents

  • Sylvain Routier, Hélène Bénédetti, Béatrice Vallée, Pascal Bonnet, Karen Plé, et al.. 4-(7H-Pyrrolo[2,3-D]pyrimidin-4-yl)-3,6-dihydropyridine-(2H)-carboxamide derivatives as Limk and/or Rock kinases inhibitors for use in the treatment of cancer. France, Patent n° : WO2021239727 A1. AMV. 2021. ⟨hal-03555349⟩
  • Sylvain Routier, Hélène Bénédetti, Frederic Buron, Marie-Aude Hiebel, Thibault Saurat, et al.. TRISUBSTITUTED PYRIDO[2,3-D]PYRIMIDINES, METHODS FOR PREPARING SAME AND THERAPEUTIC USES THEREOF. France, Patent n° : WO2014027081. 2014. ⟨hal-02131560⟩
  • Séverine Morisset-Lopez, Hélène Bénédetti. Tools for the identification od LINGO-1, LINGO-2, LINGO-3 and LINGO-4, ligands, and uses thereof. France, Patent n° : WO2011121257. BCT. 2011. ⟨hal-02130935⟩

Pré-publication, Document de travail1 document

  • Mohammed Bergoug, Christine Mosrin, Fabienne Godin, Michel Doudeau, Iva Sosic, et al.. Noncanonical structural requirements of neurofibromin SUMOylation reveal a folding-deficiency of several pathogenic mutants. 2022. ⟨hal-03668582⟩

Documents récupérés de l'archive ouverte HAL logo

BEAUFOUR Martine

email : martine.beaufour[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.78.57 ou 54.57

Lecturer within the thematic group “Functional Mass Spectrometry in Metastasis“

 


22 documents

Article dans une revue12 documents

  • Martine Beaufour, David Ginguené, Rémy Le Meur, Bertrand Castaing, Martine Cadène. Liquid Native MALDI Mass Spectrometry for the Detection of Protein-Protein Complexes. Journal of The American Society for Mass Spectrometry, 2018, 29 (10), pp.1981-1994. ⟨10.1007/s13361-018-2015-x⟩. ⟨hal-01965971⟩
  • Alexandre Morel, Jean-François Trontin, Françoise Corbineau, Anne-Marie Lomenech, Martine Beaufour, et al.. Cotyledonary somatic embryos of Pinus pinaster Ait. most closely resemble fresh, maturing cotyledonary zygotic embryos: biological, carbohydrate and proteomic analyses.. Planta, 2014, 240 (5), pp.1075-1095. ⟨10.1007/s00425-014-2125-z⟩. ⟨hal-01179478⟩
  • Alexandre Morel, Caroline Teyssier, Jean-François Trontin, Kateřina Eliášová, Bedřich Pešek, et al.. Early molecular events involved in Pinus pinaster Ait. somatic embryo development under reduced water availability: transcriptomic and proteomic analyses. Physiologia Plantarum, 2014, 152 (1), pp.184-201. ⟨10.1111/ppl.12158⟩. ⟨hal-01179486⟩
  • Caroline Teyssier, Stéphane Maury, Martine Beaufour, Cécile Grondin, Alain Delaunay, et al.. In search of markers for somatic embryo maturation in hybrid larch ( Larix × eurolepis ): global DNA methylation and proteomic analyses. Physiologia Plantarum, 2014, 150 (2), pp.271-291. ⟨10.1111/ppl.12081⟩. ⟨hal-02087600⟩
  • Martine Beaufour, Fabienne Godin, Béatrice Vallée, Martine Cadene, Hélène Bénédetti. Interaction Proteomics Suggests a New Role for the Tfs1 Protein in Yeast.. Journal of Proteome Research, 2012, 11 (6), pp.3211-3218. ⟨10.1021/pr201239t⟩. ⟨hal-00721771⟩
  • M. Beaufour, Philippe Morin, J.P. Ribet, J.C. Maurizot. HPLC quantitation of the four stereoisomers of benzoxathiepin derivatives with cellulose phenyl type chiral stationary phase and circular dichroism detection. Journal of Pharmaceutical and Biomedical Analysis, 2006, 41 (2), pp.544-548. ⟨10.1016/j.jpba.2005.11.034⟩. ⟨hal-00088834⟩
  • Martine Beaufour, Philippe Morin, Jean-Paul Ribet. Chiral separation of the four stereoisomers of a novel antianginal agent using a dual cyclodextrin system in capillary electrophoresis.. Journal of Separation Science, 2005, 28 (6), pp.529-33. ⟨10.1002/jssc.200400097⟩. ⟨hal-02087618⟩
  • M. Beaufour, B. Merelli, L. Menguy, J.-C. Cherton. Determination of the enantiomeric composition of chiral delta-2-oxazolines-1,3 by 1H and 19F NMR spectroscopy using chiral solvating agents. Chirality, 2003, 15 (5), pp.382-390. ⟨10.1002/chir.10225⟩. ⟨hal-02087633⟩
  • J.-C. Cherton, M. Beaufour, L. Menguy, B. Merelli. DETERMINATION OF THE ENANTIOMERIC COMPOSITION OF CHIRAL Δ-2-OXAZOLINES-1,3 BY 1 H AND 19 F NMR SPECTROSCOPY USING CHIRAL LANTHANIDE-SHIFT REAGENTS. Spectroscopy Letters : An International Journal for Rapid Communication, 2002, 35 (3), pp.415-437. ⟨10.1081/SL-120005675⟩. ⟨hal-02149583⟩
  • M. Beaufour, J.C Cherton, A Carlin-Sinclair, S Hamm. Delta(2)-oxazolines-1,3 and N-acylaziridines as potential proinsecticides of carboxylic acids. V. Direct thin-layer chromatography monitoring of the metabolism in locust tissues.. Journal of Chromatography B Biomedical Sciences and Applications, 2001, 761 (1), pp.35-45. ⟨10.1016/S0378-4347(01)00295-X⟩. ⟨hal-02149591⟩
  • J.-C Cherton, S Hamm, J.-C Hallé, L Menguy, M. Beaufour. Potential proinsecticides of fluorinated carboxylic acids and β-ethanolamines: IV. Evaluation of the Δ2-oxazoline-1,3 structure by 19F NMR monitoring of the in vitro metabolism in locust tissues. Journal of Fluorine Chemistry, 2001, 107 (2), pp.387-395. ⟨10.1016/S0022-1139(00)00382-1⟩. ⟨hal-02149605⟩
  • François Terrier, Martine Beaufour, Jean-Claude Halle, Jean-Claude Cherton, Erwin Buncel. A remarkably facile oxygen transfer in a nitrobenzofuroxan structure activated through σ-complex formation. Tetrahedron Letters, 2001, 42 (27), pp.4499-4501. ⟨10.1016/S0040-4039(01)00774-2⟩. ⟨hal-02149596⟩

Communication dans un congrès3 documents

  • Edison F Zhamungui, Cedric Orelle, Jean-Michel Jault, Joekeem del Rosario Arizala, Sébastien F. Poget, et al.. Structural biology of membrane proteins and their complexes using Native Liquid MALDI (NALIM) Mass Spectrometry (MS). Analytics 2022, Sep 2022, Nantes, France. ⟨hal-03845786⟩
  • Caroline Teyssier, Alexandre Morel, Jean-François Trontin, Françoise Corbineau, Anne-Marie Lomenech, et al.. Did cotyledonary somatic embryos of Pinus pinaster Ait. similar to cotyledonary zygotic embryos ?. International Conference of the IUFRO Working Party 2.09.02: Somatic Embryogenesis and Other Vegetative Propagation Technologies, Sep 2014, Vitoria-Gasteiz, Spain. ⟨hal-03809831⟩
  • Alexandre Morel, Caroline Teyssier, Jean-François Trontin, Kateřina Eliášová, Pešek Bedřichc, et al.. Multi-scale analysis of early molecular events during Pinus pinaster Ait. somatic embryo development under reduced water availability. 3. International Conference of the IUFRO Working Party 2.09.02: Somatic Embryogenesis and Other Vegetative Propagation Technologies, International Union of Forest Research Organisations (IUFRO). Vienne, AUT., Sep 2014, Vitoria-Gasteiz, Spain. 220 p. ⟨hal-02740937⟩

Poster7 documents

  • Lucija Mance, Nicolas Bigot, Edison Zhamungui Sánchez, Franck Coste, Natalia Martín-González, et al.. Studies of BTB domain polymerisation through integrative structural biology. FRISBI User Meeting 2024, CNRS campus Gif-sur-Yvette, Jan 2024, Gif sur Yvette, France. ⟨hal-04778726⟩
  • Edison F Zhamungui, Cedric Orelle, Jean-Michel Jault, Joekeem del Rosario Arizala, Sébastien F. Poget, et al.. NALIM: NATIVE LIQUID MALDI MASS SPECTROMETRY AS A NEW STRUCTURAL METHOD TO DIRECTLY CHARACTERIZE MEMBRANE PROTEIN COMPLEXES. IMSC (International Mass Spectrometry Conference), Aug 2022, Maastricht, Netherlands. ⟨hal-03863124⟩
  • Edison F Zhamungui, Martine Beaufour, Martine Cadene. Search for a high-mass calibrant for NALIM (Native Liquid MALDI MS): the case of mouse IgA. Journées Françaises de Spectrométrie de Masse, Jun 2021, Virtual, France. , 2020, ⟨10.7554/elife.56098⟩. ⟨hal-03404684⟩
  • Caroline Teyssier, Alexandre Morel, Jean-François Trontin, Francoise Corbineau, Anne-Marie Lomenech, et al.. Are cotyledonary somatic embryos of Pinus pinaster Ait. equivalent to the zygotic counterpart ?. 3. International Conference of the IUFRO Working Party 2.09.02: Somatic Embryogenesis and Other Vegetative Propagation Technologies, Sep 2014, Vitoria-Gasteiz, Spain. 2014, 3rd International Conference of the IUFRO Working Party 2.09.02: Somatic Embryogenesis and Other Vegetative Propagation Technologies. Book of Abstracts. ⟨hal-01269493⟩
  • Alexandre Morel, Caroline Teyssier, Martine Beaufour, Isabelle Reymond, Claire Le Mette, et al.. Somatic embryo maturation in maritime pine (Pinus pinaster) : contribution of a 2-DE proteomic analysis for a better understanding. 2. International Conference of the IUFRO Working Party 2.09.02, "Somatic Embryogenesis and Other Vegetative Propagation Technologies", Jun 2012, Brno, Czech Republic. 2012, Integrating vegetative propagation, biotechnologies and genetic improvement for tree production and sustainable forest management. Proceedings. ⟨hal-01268054⟩
  • Marie-Anne Lelu-Walter, Alexandre A. Morel, Caroline Teyssier, Martine Beaufour, Isabelle Reymond, et al.. Somatic embryo development in maritime pine (Pinus pinaster): a 2-DE proteomic analysis. 4. UPSC-INRA (UPRA) Bilateral Meeting, Mar 2012, Umea, Sweden. 2012, 4th UPSC-INRA (UPRA) bilateral meeting. Meeting book with abstracts. ⟨hal-02746152⟩
  • Martine Beaufour, Alexandre A. Morel, Caroline Teyssier, Luc Harvenght, Jean-François Trontin, et al.. Differential proteomics for the evaluation of the effect of environmental culture conditions on the protein expression of somatic embryos from Pinus pinaster. SMAP 2011 - 28èmes Journées Françaises de Spectrométrie de Masse, Sep 2011, Avignon, France. 2011, Spectroscopie de Masse et Analyse Protéomique. ⟨hal-02746570⟩

Documents récupérés de l'archive ouverte HAL logo

AUCAGNE Vincent

email : vincent.aucagne[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.55.77

Research director, Leader of the team “Synthetic protein and bioorthogonal chemistry”


169 documents

Article dans une revue69 documents

  • Kang Zhu, Chatrin Chatrin, Marcin J Suskiewicz, Vincent Aucagne, Benjamin Foster, et al.. Ubiquitylation of nucleic acids by DELTEX ubiquitin E3 ligase DTX3L. EMBO Reports, 2024, 25 (10), pp.4172-4189. ⟨10.1038/s44319-024-00235-1⟩. ⟨hal-04739061⟩
  • Ana Novak, Florian Kersaudy, Sylvie Berger, Séverine Morisset-Lopez, François Lefoulon, et al.. An efficient site-selective, dual bioconjugation approach exploiting N-terminal cysteines as minimalistic handles to engineer tailored anti-HER2 affibody conjugates. European Journal of Medicinal Chemistry, 2023, 260, pp.115747. ⟨10.1016/j.ejmech.2023.115747⟩. ⟨hal-04222710⟩
  • Diana Fanelli, Massimiliano Beltramo, Giuseppe Conte, Benedetta Cerretini, Didier Lomet, et al.. The Kisspeptin analogue C6 induces ovulation in jennies. Theriogenology, 2022, 189, pp.107-112. ⟨10.1016/j.theriogenology.2022.06.014⟩. ⟨hal-03746194⟩
  • Noémie de San Nicolas, Aromal Asokan, Rafael D Rosa, Sébastien N Voisin, Marie-Agnès Travers, et al.. Functional Diversification of Oyster Big Defensins Generates Antimicrobial Specificity and Synergy against Members of the Microbiota. Marine drugs, 2022, 20 (12), pp.745. ⟨10.3390/md20120745⟩. ⟨hal-04246173⟩
  • Karine Loth, Nicolas Parisot, Françoise Paquet, Hugo Terrasson, Catherine Sivignon, et al.. Aphid BCR4 Structure and Activity Uncover a New Defensin Peptide Superfamily. International Journal of Molecular Sciences, 2022, 23 (20), pp.12480. ⟨10.3390/ijms232012480⟩. ⟨hal-03862651⟩
  • Céline Landon, Yanyu Zhu, Mainak Mustafi, Jean-Baptiste Madinier, Dominique Lelièvre, et al.. Real-Time Fluorescence Microscopy on Living E. coli Sheds New Light on the Antibacterial Effects of the King Penguin beta-Defensin AvBD103b. International Journal of Molecular Sciences, 2022, This article belongs to the Special Issue Antimicrobial Peptides: Structure and Mechanism of Biological Activity, 23 (2057), pp.2057. ⟨10.3390/ijms23042057⟩. ⟨hal-03860107⟩
  • Kang Zhu, Marcin Suskiewicz, Andrea Hloušek-Kasun, Hervé Meudal, Andreja Mikoč, et al.. DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on protein substrates. Science Advances , 2022, 8 (40), ⟨10.1126/sciadv.add4253⟩. ⟨hal-03862525⟩
  • Flavie Derouin Tochon, Didier Lomet, Vincent Robert, Fabrice Reigner, Philippe Barrière, et al.. Treating mares with the long-acting kisspeptin analog C6 increases circulating gonadotropins but does not trigger ovulation. Agriculture, 2022, 12 (11), pp.1846. ⟨10.3390/agriculture12111846⟩. ⟨hal-03862471⟩
  • Skander Abboud, Mehdi Amoura, Jean-Baptiste Madinier, Brigitte Renoux, Sébastien Papot, et al.. Enzyme‐Cleavable Linkers for Protein Chemical Synthesis through Solid‐Phase Ligations. Angewandte Chemie International Edition, 2021, 60 (34), pp.18612-18618. ⟨10.1002/anie.202103768⟩. ⟨hal-05019646⟩
  • Sophie Laine, Jean-François Morfin, Mathieu Galibert, Vincent Aucagne, Celia ́ Bonnet, et al.. Lanthanide DO3A-Complexes Bearing Peptide Substrates: The Effect of Peptidic Side Chains on Metal Coordination and Relaxivity. Molecules, 2021, 26 (8), pp.2176. ⟨10.3390/molecules26082176⟩. ⟨hal-03437152⟩
  • Ahlame Saidi, Mylène Wartenberg, J.B Madinier, Guy Ilango, Seda Seren, et al.. Monitoring Human Neutrophil Activation by a Proteinase 3 Near-Infrared Fluorescence Substrate-Based Probe. Bioconjugate Chemistry, 2021, 32 (8), pp.1782-1790. ⟨10.1021/acs.bioconjchem.1c00267⟩. ⟨hal-03525228⟩
  • Skander A Abboud, Mehdi Amoura, J.B Madinier, Brigitte Renoux, Sébastien Papot, et al.. Enzyme‐Cleavable Linkers for Protein Chemical Synthesis through Solid‐Phase Ligations. Angewandte Chemie International Edition, 2021, 60 (34), pp.18612-18618. ⟨10.1002/anie.202103768⟩. ⟨hal-03335485⟩
  • Vincent Aucagne, Fabienne Burlina, Oleg Melnyk, Vladimir Torbeev. Des protéines de synthèse taillées sur mesure pour investiguer le vivant. L'Actualité Chimique, 2021, 468, pp.26-28. ⟨hal-02959387⟩
  • Skander A Abboud, Hadji H., Michel Doudeau, Hélène Bénédetti, Vincent Aucagne. A straightforward methodology to overcome solubility challenges for N-terminal cysteinyl peptide segments used in native chemical ligation. Chemical Science, 2021, 12, pp.3194 - 3201. ⟨10.1039/d0sc06001a⟩. ⟨hal-03447239⟩
  • Nicolas Guyot, Herve Meudal, Sascha Trapp, Sophie Iochmann, Anne Silvestre, et al.. Structure, function, and evolution of Gga -AvBD11, the archetype of the structural avian-double-β-defensin family. Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (1), pp.337-345. ⟨10.1073/pnas.1912941117⟩. ⟨hal-02522250⟩
  • Charlotte Rieux, Stéphane Goffinont, Franck Coste, Zahira Tber, Julien Cros, et al.. Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights. International Journal of Molecular Sciences, 2020, 21 (6), pp.2058. ⟨10.3390/ijms21062058⟩. ⟨hal-03082414⟩
  • Skander A. Abboud, Vincent Aucagne. An optimized protocol for the synthesis of N -2-hydroxybenzyl-cysteine peptide crypto-thioesters. Organic & Biomolecular Chemistry, 2020, 18 (40), pp.8199-8208. ⟨10.1039/d0ob01737j⟩. ⟨hal-02975540⟩
  • Karine Loth, Agnès Vergnes, Cairé Barreto, Sébastien N Voisin, Hervé Meudal, et al.. The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets. mBio, 2019, 10 (5), pii: e01821-19. ⟨10.1128/mBio.01821-19⟩. ⟨hal-02328576⟩
  • P.A. Parker, E.A. Coffman, K.G. Pohler, J.A. Daniel, V. Aucagne, et al.. Acute and subacute effects of a synthetic kisspeptin analog, C6, on serum concentrations of luteinizing hormone, follicle stimulating hormone, and testosterone in prepubertal bull calves. Theriogenology, 2019, 130, pp.111-119. ⟨10.1016/j.theriogenology.2019.03.002⟩. ⟨hal-02088608⟩
  • Caroline Decourt, Vincent Robert, Didier Lomet, Karine Anger, Marion Georgelin, et al.. The kisspeptin analog C6 is a possible alternative to PMSG (pregnant mare serum gonadotropin) for triggering synchronized and fertile ovulations in the Alpine goat. PLoS ONE, 2019, 14 (3), pp.e0214424. ⟨10.1371/journal.pone.0214424⟩. ⟨hal-02088631⟩
  • Julien Diharce, Mickaël Cueto, Massimiliano Beltramo, Vincent Aucagne, Pascal Bonnet. In silico peptide ligation: Iterative Residue Docking and Linking as a new approach to predict protein-peptide interactions. Molecules, 2019, 24 (7), pp.1-14. ⟨10.3390/molecules24071351⟩. ⟨hal-03525312⟩
  • Mylène Wartenberg, Ahlame Saidi, Mathieu Galibert, Alix Joulin-Giet, Julien Burlaud-Gaillard, et al.. Imaging of extracellular cathepsin S activity by a selective near infrared fluorescence substrate-based probe. Biochimie, 2019, 166, pp.84-93. ⟨10.1016/j.biochi.2019.03.013⟩. ⟨hal-02088627⟩
  • Monika Cieslikiewicz-Bouet, Svetlana Eliseeva, Vincent Aucagne, A.F. Delmas, Isabelle Gillaizeau, et al.. Near-infrared emitting lanthanide(III) complexes as prototypes of optical imaging agents with peptide targeting ability: a methodological approach. RSC Advances, 2019, 9 (3), pp.1747-1751. ⟨10.1039/c8ra09419e⟩. ⟨hal-02064990⟩
  • Mylène Wartenberg, Ahlame Saidi, Mathieu Galibert, Alix Joulin-Giet, Julien Burlaud-Gaillard, et al.. Imaging of extracellular cathepsin S activity by a selective near infrared fluorescence substrate-based probe. Biochimie, 2019, 166, pp.84-93. ⟨10.1016/j.biochi.2019.03.013⟩. ⟨hal-03677252⟩
  • Matthieu Galibert, Mylène Wartenberg, Fabien Lecaille, Ahlame Saidi, Sylvie Mavel, et al.. Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S. European Journal of Medicinal Chemistry, 2018, 144, pp.201-210. ⟨10.1016/j.ejmech.2017.12.012⟩. ⟨hal-03677245⟩
  • Matthieu Galibert, Mylène Wartenberg, Fabien Lecaille, Ahlame Saidi, Sylvie Mavel, et al.. Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S. European Journal of Medicinal Chemistry, 2018, 144, pp.201 - 210. ⟨10.1016/j.ejmech.2017.12.012⟩. ⟨hal-01702303⟩
  • David Montoir, Mehdi Amora, Zine El Abidine Aabasa, Thimmalapura Marulappa Vishwanatha, Expédite Yen-Pon, et al.. Synthesis of aryl-thioglycopeptides through chemoselective Pd-Mediated conjugation. Chemical Science, 2018, 9 (46), pp.8753-8759. ⟨10.1039/C8SC02370K⟩. ⟨hal-02622102⟩
  • Victor Terrier, Agnès F. Delmas, Vincent Aucagne. Efficient synthesis of cysteine-rich cyclic peptides through intramolecular native chemical ligation of N-Hnb-Cys peptide crypto-thioesters. Organic & Biomolecular Chemistry, 2017, 15 (2), pp.316 - 319. ⟨10.1039/c6ob02546c⟩. ⟨hal-01618781⟩
  • Guillaume Martinez, Jean-Pascal Hograindleur, Sébastien Voisin, Roland Abi Nahed, Tarek M. Abd El Aziz, et al.. Spermaurin, an La1-like peptide from the venom of the scorpion Scorpio maurus palmatus , improves sperm motility and fertilization in different mammalian species. Molecular Human Reproduction, 2017, 23 (2), pp.116-131. ⟨10.1093/molehr/gaw075⟩. ⟨hal-01618630⟩
  • Karine Loth, Soha Abou Ibrahim Alami, Chahrazed Habès, Solène Garrido, Vincent Aucagne, et al.. Complete 1H, 15N and 13C assignment of trappin-2 and 1H assignment of its two domains, elafin and cementoin. Biomolecular NMR Assignments, 2016, 10 (1), pp.223 - 226. ⟨10.1007/s12104-016-9671-1⟩. ⟨hal-01407495⟩
  • Audrey Gambade, Sami Zreika, Maxime Guéguinou, Igor Chourpa, Gaëlle Fromont, et al.. Activation of TRPV2 and BKCa channels by the LL-37 enantiomers stimulates calcium entry and migration of cancer cells.. Oncotarget, 2016, 7 (17), pp.23785-23800. ⟨10.18632/oncotarget.8122⟩. ⟨hal-01387061⟩
  • Victor P. Terrier, Hélène Adihou, Mathieu Arnould, Agnès F. Delmas, Vincent Aucagne. A straightforward method for automated Fmoc-based synthesis of bio-inspired peptide crypto-thioesters. Chemical Science, 2016, 7 (1), pp.339 - 345. ⟨10.1039/C5SC02630J⟩. ⟨hal-01407765⟩
  • Michael T. Jacobsen, Mark E. Petersen, Xiang Ye, Mathieu Galibert, George H. Lorimer, et al.. A Helping Hand to Overcome Solubility Challenges in Chemical Protein Synthesis. Journal of the American Chemical Society, 2016, 138 (36), pp.11775 - 11782. ⟨10.1021/jacs.6b05719⟩. ⟨hal-01407028⟩
  • Caroline Decourt, Vincent Robert, Karine Anger, Mathieu Galibert, Jean-Baptiste Madinier, et al.. A synthetic kisspeptin analog that triggers ovulation and advances puberty. Scientific Reports, 2016, 6 (1), pp.26908. ⟨10.1038/srep26908⟩. ⟨hal-01406943⟩
  • Dominique Lelièvre, Victor P. Terrier, Agnès F. Delmas, Vincent Aucagne. Native Chemical Ligation Strategy to Overcome Side Reactions during Fmoc-Based Synthesis of C-Terminal Cysteine-Containing Peptides. Organic Letters, 2016, 18 (5), pp.920 - 923. ⟨10.1021/acs.orglett.5b03612⟩. ⟨hal-01407492⟩
  • Mathieu Galibert, Véronique Piller, Friedrich Piller, Vincent Aucagne, Agnès F. Delmas. Combining triazole ligation and enzymatic glycosylation on solid phase simplifies the synthesis of very long glycoprotein analogues. Chemical Science, 2015, 6 (6), pp.3617-3623. ⟨10.1039/C5SC00773A⟩. ⟨hal-01178852⟩
  • Massimiliano Beltramo, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, Philippe Marceau, et al.. Rational Design of Triazololipopeptides Analogs of Kisspeptin Inducing a Long-Lasting Increase of Gonadotropins. Journal of Medicinal Chemistry, 2015, 58 (8), pp.3459-3470. ⟨10.1021/jm5019675⟩. ⟨hal-01170460⟩
  • Romain Barat, Thibaut Legigan, I. Tranoy-Opalinski, Brigitte Renoux, Elodie Peraudeau, et al.. A mechanically interlocked molecular system programmed for the delivery of an anticancer drug. Chemical Science, 2015, 6 (4), pp.2608-2613. ⟨10.1039/c5sc00648a⟩. ⟨hal-03127729⟩
  • Isidore E. Decostaire, Dominique Lelièvre, Vincent Aucagne, Agnès F. Delmas. Solid phase oxime ligations for the iterative synthesis of polypeptide conjugates. Organic & Biomolecular Chemistry, 2014, 12 (29), pp.5536-5543. ⟨10.1039/c4ob00760c⟩. ⟨hal-01178857⟩
  • Fanny Meindre, Dominique Lelièvre, Karine Loth, Oriane Mith, Vincent Aucagne, et al.. The nuclear magnetic resonance solution structure of the synthetic AhPDF1.1b plant defensin evidences the structural feature within the γ-motif. Biochemistry, 2014, 53 (49), pp.7745-54. ⟨10.1021/bi501285k⟩. ⟨hal-01118914⟩
  • Laurent Raibaut, Hélène Adihou, Rémi Desmet, Agnès F. Delmas, Vincent Aucagne, et al.. Highly efficient solid phase synthesis of large polypeptides by iterative ligations of bis(2-sulfanylethyl)amido (SEA) peptide segments. Chemical Science, 2013, 4, pp.4061-4066. ⟨10.1039/c3sc51824h⟩. ⟨hal-00944814v2⟩
  • Chrystelle Derache, Hervé Meudal, Vincent Aucagne, Kevin J Mark, Martine Cadène, et al.. Initial insights into structure-activity relationships of avian defensins.. Journal of Biological Chemistry, 2012, 287 (10), pp.7746-55. ⟨10.1074/jbc.M111.312108⟩. ⟨hal-00721842⟩
  • Antony Fernandes, Aurélien Viterisi, Vincent Aucagne, David A Leigh, Sébastien Papot. Second generation specific-enzyme-activated rotaxane propeptides.. Chemical Communications, 2012, 48 (15), pp.2083-5. ⟨10.1039/c2cc17458h⟩. ⟨hal-00678757⟩
  • Ibai E Valverde, Fabien Lecaille, Gilles Lalmanach, Vincent Aucagne, Agnès F Delmas. Synthesis of a biologically active triazole-containing analogue of cystatin A through successive peptidomimetic alkyne-azide ligations.. Angewandte Chemie International Edition, 2012, 51 (3), pp.718-22. ⟨10.1002/anie.201107222⟩. ⟨hal-00726293⟩
  • Vincent Aucagne, Ibai E Valverde, Philippe Marceau, Mathieu Galibert, Nabil Dendane, et al.. Towards the simplification of protein synthesis: iterative solid-supported ligations with concomitant purifications.. Angewandte Chemie International Edition, 2012, 51 (45), pp.11320-4. ⟨10.1002/anie.201206428⟩. ⟨hal-00748170⟩
  • Christelle Gaulier, Audrey Hospital, Bertrand Legeret, Delmas A.F., Vincent Aucagne, et al.. A water soluble Cu-I-NHC for CuAAC ligation of unprotected peptides under open air conditions.. Chemical Communications, 2012, 48, pp.4005-4007. ⟨hal-00711780⟩
  • Andrea Altieri, Vincent Aucagne, Romen Carrillo, Guy Clarkson, Daniel d'Souza, et al.. Sulfur-containing amide-based [2]rotaxanes and molecular shuttles. Chemical Science, 2011, 2 (10), pp.1922. ⟨10.1039/C1SC00335F⟩. ⟨hal-02088663⟩
  • Chrystelle Derache, Valérie Labas, Vincent Aucagne, Hervé Meudal, Céline Landon, et al.. Primary Structure and Antibacterial Activity of Chicken Bone Marrow-Derived beta-Defensins. Antimicrobial Agents and Chemotherapy, 2009, 53 (11), pp.4647-4655. ⟨10.1128/AAC.00301-09⟩. ⟨hal-00522326⟩
  • Anthony Fernandes, Aurélien Viterisi, Frédéric Coutrot, Stéphanie Potok, David A. Leigh, et al.. Rotaxane-based propeptides: protection and enzymatic release of a bioactive pentapeptide.. Angewandte Chemie International Edition, 2009, 48 (35), pp.6443-7. ⟨10.1002/anie.200903215⟩. ⟨hal-00467015⟩
  • Ibai E. Valverde, Agnès F. Delmas, Vincent Aucagne. Click a la carte: robust semi-orthogonal alkyne protecting groups for multiple successive azide/alkyne cycloadditions. Tetrahedron, 2009, 65 (36), pp.7597-7602. ⟨10.1016/j.tet.2009.06.093⟩. ⟨hal-00525398⟩
  • Dominique Lelièvre, P. Barta, Vincent Aucagne, A.F. Delmas. Preparation of peptide thioesters using Fmoc strategy through hydroxyl side chain anchoring. Tetrahedron Letters, 2008, 49 (25), pp.4016-4019. ⟨10.1016/j.tetlet.2008.04.087⟩. ⟨hal-00518141⟩
  • Vincent Aucagne, A. Tatibouët, Patrick Rollin. Thermodynamics versus kinetics in hetero-Michael cyclizations: a highly stereoselective approach to access both epimers of a C-D-mannopyranoside. Tetrahedron Letters, 2008, 49, pp.4750-4753. ⟨10.1016/j.tetlet.2008.05.117⟩. ⟨hal-00512453⟩
  • Julie Broggi, Nicolas Joubert, Vincent Aucagne, Sabine Berteina-Raboin, S. Diez-Gonzalez, et al.. Alkyne-Azide Click Chemistry Mediated Carbanucleosides Synthesis. Nucleosides, Nucleotides and Nucleic Acids, 2007, 26 (10-12), pp.1391-1394. ⟨10.1080/15257770701534139⟩. ⟨hal-02086003⟩
  • Isidore P. Decostaire, Dominique Lelièvre, Vincent Aucagne, Agnès F. Delmas. Synergic effect of hydride and proton donors in the Pd(0)-mediated deprotection of Nα-Aloc proline derivatives. Tetrahedron Letters, 2007, 48, pp.6523-6526. ⟨10.1016/j.tetlet.2007.07.061⟩. ⟨hal-00166600⟩
  • Vincent Aucagne, J. Berna, Jd Crowley, Sm Goldup, Kd Haenni, et al.. Catalytic "Active-Metal" template synthesis of [2]rotaxanes, [3]rotaxanes, and molecular shuttles, and some observations on the mechanism of the Cu(I)-catalyzed azide-alkyne 1,3-cycloaddition. Journal of the American Chemical Society, 2007, 129, pp.11950-11963. ⟨hal-00275210⟩
  • J. Broggi, N. Joubert, Vincent Aucagne, T. Zevaco, S. Berteina-Raboin, et al.. Study of different copper(I) catalysts for the "click chemistry" approach to carbanucleosides. Nucleosides, Nucleotides and Nucleic Acids, 2007, 26, pp.779-783. ⟨hal-00275217⟩
  • Vincent Aucagne, Kevin Hänni, David Leigh, Paul Lusby, D Barney Walker. Catalytic “Click” Rotaxanes: A Substoichiometric Metal-Template Pathway to Mechanically Interlocked Architectures. Journal of the American Chemical Society, 2006, 128 (7), pp.2186-2187. ⟨10.1021/ja056903f⟩. ⟨hal-02086010⟩
  • Vincent Aucagne, David A. Leigh. Chemoselective formation of successive triazole linkages in one pot: "click-click" chemistry. Organic Letters, 2006, 8 (20), pp.4505-4507. ⟨10.1021/ol061657d⟩. ⟨hal-00387909⟩
  • Vincent Aucagne, David Leigh, Julia Lock, Andrew Thomson. Rotaxanes of Cyclic Peptides. Journal of the American Chemical Society, 2006, 128 (6), pp.1784-1785. ⟨10.1021/ja057206q⟩. ⟨hal-02086005⟩
  • Franck Amblard, Vincent Aucagne, Pierre Guenot, Raymond Schinazi, Luigi Agrofoglio. Synthesis and antiviral activity of novel acyclic nucleosides in the 5-alkynyl- and 6-alkylfuro[2,3-d]pyrimidine series. Bioorganic and Medicinal Chemistry, 2005, 13 (4), pp.1239-1248. ⟨10.1016/j.bmc.2004.11.057⟩. ⟨hal-02086014⟩
  • Vanessa Escuret, Vincent Aucagne, Nicolas Joubert, David Durantel, Kimberly Rapp, et al.. Synthesis of 5-haloethynyl- and 5-(1,2-dihalo)vinyluracil nucleosides: Antiviral activity and cellular toxicity. Bioorganic and Medicinal Chemistry, 2005, 13 (21), pp.6015-6024. ⟨10.1016/j.bmc.2005.06.021⟩. ⟨hal-02086013⟩
  • V. Aucagne, C. Lorin, A. Tatibouët, P. Rollin. Regioselective Michael-induced cyclisation of γ- and δ-hydroxy vinyl sulfides and vinyl dithiocarbamates. Tetrahedron Letters, 2005, 46 (25), pp.4349-4352. ⟨10.1016/j.tetlet.2005.04.112⟩. ⟨hal-02086017⟩
  • Vincent Aucagne, Franck Amblard, Luigi Agrofoglio. Highly Efficient AgNO3-Catalyzed Preparation of Substituted Furanopyrimidine Nucleosides [cf. (III)].. ChemInform, 2005, 36 (18), ⟨10.1002/chin.200518181⟩. ⟨hal-02086027⟩
  • Vincent Aucagne, Sabine Berteina-Raboin, Pierre Guenot, Luigi Agrofoglio. Palladium-Catalyzed Synthesis of Uridines on Polystyrene-Based Solid Supports. Journal of Combinatorial Chemistry, 2004, 6 (5), pp.717-723. ⟨10.1021/cc049976o⟩. ⟨hal-02086022⟩
  • Vincent Aucagne, Arnaud Tatibouët, Patrick Rollin. Wittig approach to carbohydrate-derived vinyl sulfides, new substrates for regiocontrolled ring-closure reactions. Tetrahedron, 2004, 60 (8), pp.1817-1826. ⟨10.1016/j.tet.2003.12.040⟩. ⟨hal-02086021⟩
  • Isabelle Gillaizeau, Irene m. Lagoja, Steve p. Nolan, Vincent Aucagne, Jef Rozenski, et al.. Straightforward Synthesis of Labeled and Unlabeled Pyrimidine d4Ns via 2′,3′-Diyne seco Analogues through Olefin Metathesis Reactions. European Journal of Organic Chemistry, 2003, 2003 (4), pp.666-671. ⟨10.1002/ejoc.200390107⟩. ⟨hal-02086029⟩
  • Vincent Aucagne, Maria Aversa, Anna Barattucci, Paola Bonaccorsi, Placido Giannetto, et al.. Sulfenic acids in the carbohydrate field. Synthesis of transient glycosulfenic acids and their addition to unsaturated acceptors.. Journal of Organic Chemistry, 2002, 67 (20), pp.6925-30. ⟨hal-02086034⟩
  • Vincent Aucagne, David Gueyrard, Arnaud Tatibouët, Alain Quinsac, Patrick Rollin. Synthetic Approaches to C-Glucosinolates. Tetrahedron, 2000, 56 (17), pp.2647-2654. ⟨10.1016/S0040-4020(00)00153-8⟩. ⟨hal-02086037⟩
  • V. Aucagne, D. Gueyrard, A. Tatibout, S. Cottaz, H. Driguez, et al.. the first synthesis of c-glucotropeolin. Tetrahedron Letters, 1999, pp.7319-7321. ⟨hal-00309763⟩

Communication dans un congrès38 documents

  • Noémie de San Nicolas, A. Jouault, Aromal Asokan, Lhousseine Touqui, K Loth, et al.. Big-Defensin Diversification in Oysters: Implications for Host Defense and Microbiota Management (D. Destoumieux-Garzon INVITED SPEAKER). IMAP 2024 International Meeting on Antimicrobial Peptides, Sep 2024, Londres, United Kingdom. ⟨hal-04882843⟩
  • Noémie de San Nicolas, Aromal Asokan, Rafaela da Rosa, Vincent Aucagne, K. Loth, et al.. Big defensins: A Diversified Family of Antimicrobial Peptides Confronting Versatile Microbial Environments (DELPHINE DESTOUMIEUX-GARZON INVITED SPEAKER). Antimicrobial Peptides. Yesterday, Today, and Tomorrow, Oct 2023, Omaha, Nebraska, USA, United States. ⟨hal-04885227⟩
  • Hugo Terrasson, Karine Loth, Nicolas Parisot, Françoise Paquet, Isabelle Rahioui, et al.. Bacteriocyte-specific Cysteine-Rich (BCR) peptides form a new aphid-specific defensin-like family and are promising regulators of aphid symbiosis. Rencontres du Réseau Ecologie des Interactions Durables (REID), May 2023, Poitiers, France. ⟨hal-04633283⟩
  • Noémie de San Nicolas, A. Asokan, R.D. Rosa, S.N. Voisin, Marie Agnès Travers, et al.. Functional DIversification of Big-Defensins and the shaping of oyster microbiota. AMP 2022 7th International Symposium on Antimicrobial Peptides, Nov 2022, Paris, France. ⟨hal-03976756⟩
  • A. Asokan, Noémie de San Nicolas, H. Meudal, K. Loth, Delphine Destoumieux-Garzon, et al.. Enabling the synthesis of hydrophobic proteins using NCL-labile solubilizing tags: a case study of Crassostrea gigas big defensin 3. 22nd GFPP & 5th BPGM French-Belgian Joint Meeting, Groupe Français des Peptides et Protéines, May 2022, Port Leucate, France. ⟨hal-03976595⟩
  • Hugo Terrasson, Karine Loth, Nicolas Parisot, Françoise Paquet, Isabelle Rahioui, et al.. Les peptides « Bacteriocyte-specific Cystein-Rich » : une nouvelle famille de défensine. Régulateurs de la symbiose chez les pucerons ?. 9ème Journées du GDR "MultiFonction des Peptides AntiMicrobiens" (MuFoPAM), Oct 2022, Amboise, France. ⟨hal-04633233⟩
  • Hugo Terrasson, Karine Loth, Nicolas Parisot, Françoise Paquet, Isabelle Rahioui, et al.. Peptides « Bacteriocyte-specific Cysteine Rich » (BCR) : un rôle dans le contrôle de la symbiose ? Focus sur BCR4 chez le puceron du pois.. 12èmes rencontres du réseau français de Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), May 2022, Nice, France. ⟨hal-04771966⟩
  • Vincent Aucagne. Développements méthodologiques pour la synthèse chimique de protéines. 33e colloque Biotechnocentre, Oct 2021, Chaumont-sur-Tharonne, France. ⟨hal-03563421⟩
  • Josef Hamacek, Edina Numanovic, Vincent Aucagne. Determination of Binding Affinities with Flow-Induced Dispersion Analysis: The Case of Synthetic Affibodies. NECTAR, annual meeting, Aug 2021, Lisbon, Portugal. ⟨hal-03482197⟩
  • Vincent Aucagne. A chemical toolbox for simplifying chemical protein synthesis. Congrès annuel de la Société Française de Biochimie et Biologie Moléculaire (SFBBM21), Jul 2021, Paris, France. ⟨hal-03563426⟩
  • David Montoir, Mehdi Amoura, Zine El Abidine Ababsa, T.M. Vishwanatha, Expédite Yen-Pon, et al.. Synthesis of aryl-thioglycopeptides through chemoselective Pd-mediated conjugation. 4. GFPP Chemical Ligation Meeting (Ligation2020), Jan 2020, Orléans, France. ⟨hal-02892772⟩
  • K Loth, Agnès Vergnes, C Barreto, S Voisin, H. Meudal, et al.. Exploring ancestral traits lost during molecular evolution of Big-Defensins Towards β-defensins (DELPHINE DESTOUMIEUX-GARZON, INVITED SPEAKER). Gordon Research Conference "Antimicrobial Peptides", Feb 2019, Barga, Italy. ⟨hal-04891216⟩
  • S. Abboud, V. Piller, S. Papot, V. Aucagne. Développement de bras enzymo-labiles pour la synthèse totale de protéines par ligations chimiques sur support solide. 32e Colloque Biotechnocentre, Oct 2019, Seillac, France. ⟨hal-02893386⟩
  • Vincent Aucagne. Séminaire invité : Development of a molecular toolbox to simplify the chemical synthesis of proteins. Institut de Chimie des Substances Naturelles, Mar 2019, Gif-sur-Yvette, France. ⟨hal-02974369⟩
  • S. Abboud, Mehdi Amoura, V. P. Terrier, A. F. Delmas, V. Aucagne. An improved synthesis of N-Hnb-Cys peptide crypto-thioesters ‒studies on the epimerization of cysteine during solid-phase reductive amination. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02892784⟩
  • H. Meudal, Nicolas Guyot, K. Loth, G. Jousset, S. Trapp, et al.. Gga-AvBD11, the archetype of a new structural family of defensins. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02892790⟩
  • D. Montoir, Mehdi Amoura, A. Ababsa Z. E., M. Vishwanatha T., E. Yen-Pon, et al.. ”Tag and modify” strategy for the Pd-catalyzed Thioglycoconjugation of peptides. Noncanonical amino acids (ncAAs): Tools for biological and biophysical investigations, Oct 2019, Paris, France. ⟨hal-02892775⟩
  • G. Lalmanach, M. Wartenberg, M. Galibert, A. Saidi, F. Lecaille, et al.. Design of both pseudopeptide inhibitors and imaging probes derived from a unique substrate sequence: a versatile molecular toolbox for studying proteases. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02892793⟩
  • Julien Diharce, Mickaël Cueto, Vincent Aucagne, Massimiliano Beltramo, Pascal Bonnet. Fragment covalent docking (FCD) approach: An innovative in silico tools for the prediction of peptide-protein interaction. 256th National Meeting and Exposition of the American-Chemical-Society Nanoscience, Nanotechnology and Beyond (ACS), American Chemical Society (ACS). USA., Aug 2018, Boston, United States. pp.2. ⟨hal-02734800⟩
  • T.M. Vishwanatha, C. Decourt, V.P. Terrier, V. Robert, M. Galibert, et al.. Rational design of kisspeptin analogs for the control of reproduction. 4th Belgian Peptide Group Meeting, Feb 2018, Bruxelles, Belgium. ⟨hal-02892809⟩
  • Vincent Aucagne. Séminaire invité : Développement d’une boîte à outils pour simplifier la synthèse chimique de protéines. Institut des Biomolécules Max Mousseron, Nov 2018, Montpellier, France. ⟨hal-02974372⟩
  • Nicolas Guyot, Hervé Meudal, Karine Loth, Guillaume Jousset, Anne Silvestre, et al.. 1ère structure 3D d’une défensine à double motif β-défensine, Gga-AvBD11 du poulet Gallus gallus, et explorations fonctionnelles. 5es Journées GDR MuFoPAM, Centre National de la Recherche Scientifique (CNRS). FRA., Oct 2018, Paris, France. ⟨hal-02788993⟩
  • Mehdi Amoura, D. Sarraf, L. Nauton, V.P. Terrier, D. Lelièvre, et al.. N-2-hydroxybenzyl-cysteine peptide crypto-thioesters for native chemical ligation. 35th European Peptide Symposium (EPS35), Aug 2018, Dublin, Ireland. ⟨hal-02892802⟩
  • A.F. Delmas, Vincent Aucagne. Synthesis and structural characterization of naturally-occuring disulfide rich antimicrobial peptides Gyros Protein Technologies. European peptide symposium, Aug 2018, Dublin, Ireland. ⟨hal-02919154⟩
  • Vincent Aucagne. Séminaire invité : Développement d'une boîte à outils pour simplifier la synthèse chimique de protéines. Laboratoire BioCIS - Biomolécules : Conception, Isolement et Synthèse, Université Paris-Sud, Apr 2017, Châtenay-Malabry, France. ⟨hal-02974390⟩
  • Vincent Aucagne. Séminaire invité : Development of a molecular toolbox to simplify the chemical synthesis of proteins and constrained peptides natural products. Vrije Universiteit Brussel, May 2017, Bruxelles, Belgium. ⟨hal-02974374⟩
  • Vincent Aucagne. Séminaire invité : Triazolopeptides as proteolysis-resistant, highly potent KISS1R agonists. Universiteit Gent, May 2017, Gand, Belgium. ⟨hal-02974376⟩
  • Vincent Aucagne. Séminaire invité : Development of a molecular toolbox to simplify the chemical synthesis of proteins and constrained peptides natural products. Institut Européen de Chimie et Biologie, Apr 2017, Bordeaux, France. ⟨hal-02974400⟩
  • Vincent Aucagne. Simplifier la synthèse totale de protéines et de mini-protéines riches en pont disulfures. 7e Symposium Francophone de Synthèse Totale (SFST7), Jun 2017, Orsay, France. ⟨hal-02892762⟩
  • A. Casas-Mora, M. Galibert, A.F. Delmas, V. Aucagne. A non-chromatographic catch-and-release purification method to simplify the synthesis of cysteine-rich peptides. 20e réunion du Groupe Français des Peptides et des Protéines (GFPP 20), Mar 2017, Arcachon, France. ⟨hal-02893392⟩
  • A.F. Delmas, V.P. Terrier, R.D. Rosa, A. Bressan, P. Marceau, et al.. Native Chemical ligation simplifies the access of multidomain antimicrobial peptides: application to the study of big-defensins. International symposium on AntiMicrobial Peptides (AMP2016), Jun 2016, Montpellier, France. ⟨hal-02892834⟩
  • Vincent Aucagne. Séminaire invité : Development of a molecular toolbox to simplify the chemical synthesis of proteins.. Institut Curie, Jun 2016, Paris, France. ⟨hal-02974405⟩
  • Vincent Aucagne. Séminaire invité : A molecular toolbox for exploring new chemical spaces: making simpler the synthesis of biologically- and therapeutically-relevant small proteins and complex peptides. Sanofi, Sep 2016, Francfort, Germany. ⟨hal-02974403⟩
  • Massimiliano Beltramo, Vincent Aucagne, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, et al.. Design and profiling of new selective KISS1R agonists that stimulate the reproductive system. 8. International Congress of Neuroendocrinology, Society for Behavioral Neuroendocrinology (SBN). USA., Aug 2014, Sydney, Australia. ⟨hal-02738894⟩
  • Massimiliano Beltramo, Vincent Aucagne, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, et al.. New KISS1R agonists with potential for the treatment of reproductive disorder. 11. International Symposium on GnRH: The hypothalamic-pituitary-gonadal axis in cancer and reproduction, Kenes International. USA., Feb 2014, Salzburg, Austria. ⟨hal-02742248⟩
  • Chrystelle Derache, Hervé Meudal, Vincent Aucagne, Martine Cadène, Agnès Delmas, et al.. First insights into the structure-activity relationships of avian beta-defensins.. 2nd International Symposium on Antimicrobial Peptides - Food Veterinary Medical and Novel Applications., 2009, Saint-Malo, France. ⟨hal-02753345⟩
  • Anne-Christine Lalmanach, Chrystelle Derache, Evelyne Esnault, Valérie Labas, V. Aucagne, et al.. Avian beta-defensins in the control of bacterial pathogens of chicken digestive tract. 2. International Symposium on Antimicrobial Peptides. Food Veterinary Medical and Novel Applications, Jun 2009, Saint-Malo, France. ⟨hal-02751627⟩
  • P. da Silva, I. Rahioui, C. Laugier, Yvan Rahbé, A. Delmas, et al.. PA1b, un peptide à activité insecticide : relations structure/fonction. XVème Colloque de Physiologie de l'Insecte, 2007, Rennes (France), juillet 2007, France. pp.1-1. ⟨hal-00391295⟩

Poster56 documents

  • Hugo Terrasson, Karine Loth, Nicolas Parisot, Françoise Paquet, Isabelle Rahioui, et al.. The aphid BCR4 structure and activity uncover a new defensin peptide superfamily. XXVII International Congress of Entomology, Aug 2024, Kyoto, Japan. ⟨hal-04702878⟩
  • Hugo Terrasson, Karine Loth, Françoise Paquet, Nicolas Parisot, Isabelle Rahioui, et al.. The Bacteriocyte-specific Cysteine-Rich (BCR) proteins: a role in the control of aphid symbiosis ?. Journée scientifique enjeu « santé globale et bio‐ingénierie » de l'INSA Lyon, Apr 2023, Villeurbanne, France. ⟨hal-04633269⟩
  • Hugo Terrasson, Karine Loth, Nicolas Parisot, Françoise Paquet, Isabelle Rahioui, et al.. Bacteriocyte specific Cystein Rich peptides, a new defensin like protein family , are promising regulators of aphid symbiosis. 10th congress of the International Symbiosis Society (ISS) - 3rd International Conference on Holobionts (joint meeting), Jul 2022, Lyon, France. ⟨hal-04771990⟩
  • Noémie de San Nicolas, A Asokan, S Voisin, A Delmas, Vincent Aucagne, et al.. Role of big-defensins in the control of oyster microbiota. 8ème journées du GDR MuFoPAM, Oct 2021, Marseille, France. . ⟨hal-04888804⟩
  • S. Abboud, A.F. Delmas, V. Aucagne. Synthesis of N-Hnb-Cys peptide crypto-thioesters: identification of imadozolidinone and epimerized side products, and development of an optimized protocol. 4th GFPP Chemical Ligation Meeting (Ligation2020), Jan 2020, Orléans, France. ⟨hal-02893398⟩
  • T.M. Vishwanatha, D. Montoir, Mehdi Amoura, Z. El Ababsa, E. Yen-Pon, et al.. Synthesis of aryl-thioglycopeptides through chemoselective Pd-catalyzed conjugation. 26. American Peptide Symposium (APS 2019), Jun 2019, Monterey, Californie, United States. ⟨hal-02893419⟩
  • Herve Meudal, Françoise Paquet, Laurence Jouvensal, V. Aucagne, A.F. Delmas, et al.. Chemical synthesis and natural abundance NMR: an efficient tandem to unravel 3D structures of unlabeled disulfide rich peptides. 21e congrès du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02919180⟩
  • S. Abboud, Mehdi Amoura, P. Terrier V., A.F. Delmas, V. Aucagne. N-Hnb-Cys peptide crypto-thioesters: optimized synthetic protocol and second generation device. Noncanonical amino acids (ncAAs): Tools for biological and biophysical investigations, Oct 2019, Paris, France. ⟨hal-02893409⟩
  • S. Abboud, Mehdi Amoura, V.P. Terrier, A.F. Delmas, V. Aucagne. An improved synthesis of N-Hnb-Cys peptide crypto-thioesters - studies on the epimerization of cysteine during solid-phase reductive amination. 8th Chemical Protein Synthesis meeting (CPS2019), Jun 2019, Berlin, Germany. ⟨hal-02893426⟩
  • Françoise Paquet, K. Loth, C. Arnoult, V. Aucagne, A.F. Delmas. Spermaurin, a scorpion venom disulfide-rich miniprotein that improves sperm motility and fertilization in mammals.. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02893462⟩
  • F. Coste, G. Chaume, J.-B. Madinier, I. Rahioui, B. Castaing, et al.. Incorporation of trifluoromethylated pseudoproline in an entomotoxic knottin: effects on oxidative folding, 3D structure and biological activity. 21e congrès du Groupe Français des Peptides et des Protéines (GFPP), May 2019, Amboise, France. ⟨hal-02893471⟩
  • H. Meudal, K. Loth, G. Jousset, V. Aucagne, Nicolas Guyot, et al.. A new structural family for antimicrobial defensins. NMR : a tool for biology XIth, Jan 2019, Paris, France. ⟨hal-02919171⟩
  • Vincent Robert, Vishwanatha Thimmalapura Marulappa, Didier Lomet, Caroline Decourt, Laia Miret, et al.. Design of GPR54 (Kiss1r) crosslinker peptides: new tools to study G protein-coupled receptors (GPCR) localization and function. SNE, Oct 2019, Tours, France. ⟨hal-03381932⟩
  • T.M. Vishwanatha, D. Montoir, Mehdi Amoura, Z. El Ababsa, E. Yen-Pon, et al.. Synthesis of aryl-thioglycopeptides through chemoselective Pd-catalyzed conjugation. 21. Réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02893488⟩
  • S.V. Eliseeva, V. Aucagne, A.F. Delmas, S. Petoud, I. Gillaizeau. Near-infrared emitting lanthanide molecules, macromolecules and nanomaterials: New perspectives of optical biological imaging of living systems. GDR AIm 2018 - 1ères Journées du GDR AİM: "Agents d'imagerie moléculaire", Jun 2018, Orléans, France. ⟨hal-03326661⟩
  • S. Abboud, V. Piller, S. Papot, A.F. Delmas, V. Aucagne. Development of chemo-enzymatic methodologies for the total synthesis of proteins through solid-supported chemical ligation. 31e Colloque Biotechnocentre, Oct 2018, Seillac, France. ⟨hal-02894152⟩
  • T.M. Vishwanatha, C. Decourt, V.P. Terrier, V. Robert, J.-B. Madinier, et al.. Rational design of kisspeptin analogs for the control of the reproductive system. 25th SCT Young Research Fellows meeting, Mar 2018, Orléans, France. ⟨hal-02894277⟩
  • T.M. Vishwanatha, C. Decourt C, V. Robert, M. Galibert, J.-B. Madinier, et al.. Long-lasting increase of gonadotropins by rational design of lipophilic kisspeptin analogs. 2018 International Symposium on Chemical Biology, Jan 2018, Genève, Switzerland. ⟨hal-02894282⟩
  • R. Cameron, R. Kirkwood, M. Beltramo, V. Aucagne, A. Tilbrook. A single injection of compound 6 evoked an LH surge and ovulation in 18 week old gilts. 100th annual meeting of the Endocrine Society (ENDO 2018), Mar 2018, Chicago, Illinois, United States. Endocrine Reviews, 39 (Suppl. 1), pp.281-282, The Endocrine Society’s 100th Annual Meeting and Expo. ⟨10.1093/edrv/39.supp.1⟩. ⟨hal-02894272⟩
  • Mehdi Amoura, V.P. Terrier, A.F. Delmas, V. Aucagne. Second generation N-2-hydroxybenzyl-cysteine peptide crypto-thioesters for native chemical ligation. 35th European Peptide Symposium (EPS35), Aug 2018, Dublin, Ireland. ⟨hal-02894157⟩
  • Mehdi Amoura, V.P. Terrier, A.F. Delmas, V. Aucagne. Design and optimization of alternative thioester precursors to simplify protein synthesis by native chemical ligation. 25th SCT Young Research Fellows meeting, Mar 2018, Orléans, France. ⟨hal-02894273⟩
  • David Montoir, Mehdi Amoura, Zine El Abidine Ababsa, Thimmalapura Marulappa Vishwanatha, Expédite Yen-Pon, et al.. Synthesis of aryl-Thioglycopeptides through chemoselective Pd-catalyzed conjugation. 35 th European Peptide Symposium, Aug 2018, Dublin, Ireland. 2018. ⟨hal-02734043⟩
  • F. Coste, G. Chaume, J.-B. Madinier, I. Rahioui, B. Castaing, et al.. Incorporation of trifluoromethylated pseudoproline in an entomotoxic knottin: effects on oxidative folding, 3D structure and biological activity. 35th European Peptide Symposium (EPS35), Aug 2018, Dublin, Ireland. ⟨hal-02894161⟩
  • Massimiliano Beltramo, Caroline Decourt, Vincent Robert, Didier Lomet, Vincent Aucagne. In non-breeding ewes the kisspeptin analog c6 triggers ovulation without progestogen priming. 9th International Congress of Neuroendocrinology, Jul 2018, Toronto, Canada. , 2018, The 9th International Congress of Neuroendocrinology. Abstract book. ⟨hal-02735160⟩
  • Mehdi Amoura, V.P. Terrier, A.F. Delmas, V. Aucagne. N-2-Hydroxybenzyl-Cysteine Peptides as Efficient Thioester Surrogates for Native Chemical Ligation. 4th Belgian Peptide Group Meeting, Feb 2018, Bruxelles, Belgium. ⟨hal-02894279⟩
  • H. Meudal, Laurence Jouvensal, K. Loth, Françoise Paquet, V. Aucagne, et al.. Chemical synthesis and natural abundance NMR: An efficient tandem to unravel 3D structures of Disulfide Rich Miniproteins. 35th European Peptide Symposium, Aug 2018, Dublin, Ireland. ⟨hal-02920483⟩
  • C. Decourt, V. Robert, Didier Lomet, V. Aucagne, Massimiliano Beltramo. The kisspeptin analog C6 triggers ovulation in non-breeding ewe in the absence of progestogen priming. 9. International Congress of Neuroendocrinology (ICN 2018), Jul 2018, Toronto, Canada. ⟨hal-02894264⟩
  • Françoise Paquet, H. Meudal, Laurence Jouvensal, K. Loth, V. Aucagne, et al.. Synthèse chimique et RMN en abondance naturelle : un tandem efficace pour résoudre les structures 3D de peptides/protéines riches en ponts disulfure. 5es journées annuelles du GDR MuFoPAM, Oct 2018, Paris, France. ⟨hal-02920025⟩
  • Mehdi Amoura, V.P. Terrier, D. Lelièvre, A.F. Delmas, V. Aucagne. N-2-Hydroxybenzyl-Cysteine Peptides as Efficient Thioester Surrogates for Native Chemical Ligation. 7th Chemical Protein Synthesis meeting (CPS 2017), Sep 2017, Haifa, Israel. ⟨hal-02894290⟩
  • Caroline Decourt, Vincent Robert, Didier Lomet, Karine Anger, A. Delmas, et al.. Investigation of tachyphylaxis of LH response following repeated injections of the kisspeptin analog C6. Colloque International NeuroFrance 2017, May 2017, Bordeaux, France. 2017, Colloque International NeuroFrance 2017. ⟨hal-01605114⟩
  • C. Decourt, V. Robert, D. Lomet, Vincent Aucagne, G. Anderson, et al.. Pattern of LH secretion after repeated treatment with kisspeptin analog C6 reveals differential sensitivity between mice and ewes. 42. Colloque de la société de neuroendocrinologie (SNE 2017), Sep 2017, Dijon, France. ⟨hal-02894288⟩
  • Mehdi Amoura, V.P. Terrier, D. Lelièvre, A.F. Delmas, V. Aucagne. N-2-Hydroxybenzyl-Cysteine Peptides as Efficient Thioester Surrogates for Native Chemical Ligation. 25th American Peptide Symposium (APS 25), Jun 2017, Whistler, Canada. ⟨hal-02894293⟩
  • Vincent Robert, Vincent Aucagne, Caroline Decourt, Massimiliano Beltramo. Do endogenous kisspeptins and synthetic agonist C6 trigger different intracellular responses?. 42e colloque de la société de neuroendocrinologie (SNE 2017), Sep 2017, Dijon, France. 2017, 42ème Colloque de la Société de Neuroendocrinologie. ⟨hal-02733747⟩
  • A. Casas-Mora, M. Galibert, A.F. Delmas, V. Aucagne. Design of a New N-Terminal Linker for the Capture-and-Release Purification of Biologically-Relevant Disulfide-Rich Peptides. 25th American Peptide Symposium (APS 25), Jun 2017, Whistler, Canada. ⟨hal-02894295⟩
  • Vincent Aucagne, E. Schmitt, P. Bulet, C. Arnoult.. NCL-based total synthesis of spermaurin, a scorpion venom disulfide-rich miniprotein that improves sperm motility and fertilization in mammals. 20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France. . ⟨hal-02453195⟩
  • N. J. Stanley, D. Lelièvre, A.F. Delmas, Vincent Aucagne. Development of highly base-labile linkers for the catch-and-release purification of difficult peptides. Application to Avian beta-defensin 2. 20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France. . ⟨hal-02453245⟩
  • A. Delmas, K. Loth, Herve Meudal, V. Terrier, R.D. Rosa, et al.. NCL-based synthesis, 3D structure and first insight into antimicrobial properties of Cg-BigDef1, an oyster big defensin active at high salinity. NMR: a tool for Biology Xth, Jan 2017, Paris, France. ⟨hal-02453460⟩
  • Caroline Decourt, Vincent Robert, Didier Lomet, Vincent Aucagne, Greg Anderson, et al.. Investigation of a kisspeptin analog effects both on synchronization of ovulation and puberty onset in domestic mammals and in rodents. ReproSciences 2017, Apr 2017, Tours, France. 75 p., 2017, 2èmes Journées Scientifiques du GdR Repro. ⟨hal-01603310⟩
  • Mehdi Amoura, V. P. Terrier, A.F. Delmas, Vincent Aucagne. Second generation N-2-hydroxybenzyl-cysteine peptide crypto-thioesters: achieving very fast NCL kinetics at neutral pH. 20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France. ⟨hal-02453275⟩
  • A.F. Delmas, K. Loth, Herve Meudal, V.P. Terrier, R.D. Rosa, et al.. NCL-based synthesis, 3D structure and first insight into antimicrobial properties of Cg-BigDef1, an oyster big defensin active at high salinity. 20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France. ⟨hal-02894301⟩
  • M. Beltramo, V. Robert, D. Lomet, K. Anger, M. Galibert, et al.. A new selective kisspeptin analog, C6, that advance puberty in mice and stimulate fertile ovulation in ewe. British Society for Neuroendocrinology Annual Meeting, Sep 2016, Glasgow, United Kingdom. ⟨hal-02453336⟩
  • V. P. Terrier, H. Adihou, D. Lelièvre, Mehdi Amoura, A.F. Delmas, et al.. A straightforward strategy for automated Fmoc-based synthesis of peptide “crypto-thioesters”. Application to the total synthesis of biologically-relevant disulfide-rich peptides. Journées de Chimie Organique de la Société Chimique de France (JCO2016), Dec 2016, Palaiseau, France. . ⟨hal-02453318⟩
  • A.F. Delmas, V.P. Terrier, R.D. Rosa, A. Bressan, P. Marceau, et al.. Native Chemical ligation simplifies the access of multi-domain antimicrobial peptides: application to the study of big-defensins. 34th European Peptide Symposium 2016 (EPS2016), Sep 2016, Leipzig, Germany. ⟨hal-02895296⟩
  • Agnes Vergnes, Victor P. Terrier, Bressan Albert, Rafael Diego Rosa, Vincent Aucagne, et al.. Laligation native simplifie l’étude de l’activité etdu mécanismed’action des peptides antimicrobiens à multiples domaines :cas des Big défensines d’huître.. IIIèmes journées annuelles MuFoPAM « MultiFonction des Peptides AntiMicrobiens », Oct 2016, Tours, France. ⟨hal-02128427⟩
  • Caroline Decourt, Vincent Robert, Didier Lomet, Karine Anger, M. Galibert, et al.. Induction of fertile ovulation and puberty advancement by a new kisspeptin analog. 18th International Congress on Animal Reproduction (ICAR), Jun 2016, Tours, France. 676 p., 2016, 18th International Congress on Animal Reproduction (ICAR). ⟨hal-01604087⟩
  • A. Casas-Mora, M. Galibert, A.F. Delmas, V. Aucagne. A capture-and-release purification strategy to simplify the synthesis of disulfide-rich peptides. 1st PSL Chemical Biology Meeting, Dec 2016, Paris, France. . ⟨hal-02453303⟩
  • Caroline Decourt, Vincent Robert, Didier Lomet, Karine Anger, Mathieu Galibert, et al.. Induction of synchronized fertile ovulation by a new selective agonist of kisspeptin receptor. 1 Journées du GdR 3606 Repro, Apr 2015, Rennes, France. 105 p., 2015, 1ères Journées Scientifiques du GdR Repro. ⟨hal-02742326⟩
  • Vincent Aucagne, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, P. Marceau, et al.. Rational design of triazolo-lipopeptides analogs of kisspeptin inducing a long-lasting increase of gonadotrophins. 19. Congrès du Groupe Français des Peptides et des Protéines, May 2015, Port-Bail, United States. 2015. ⟨hal-02793091⟩
  • Vincent Aucagne, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, P. Marceau, et al.. Rational design of triazolo-lipopeptides analogs of kisspeptin inducing a long-lasting increase of gonadotropins. 24. Meeting of the American Peptide Society, Jun 2015, Orlando, United States. 2015, 24th Meeting of the American Peptide Society. ⟨hal-02741835⟩
  • Caroline Decourt, Karine Anger, Vincent Robert, Vincent Aucagne, Mathieu Galibert, et al.. Development of new kisspeptin analogs to stimulate the reproductive system. International Conference on Gonadotropins & Receptors, Sep 2014, Tours, France. , 2014, ICGRIII International Conference on Gonadotropins & Receptors. ⟨hal-02744014⟩
  • Massimiliano Beltramo, V. Aucagne, Vincent Robert, M. Galibert, J.B. Madinier, et al.. Design and functional profiling of new KISS1R agonists. 2. Annual Meeting of the GDR RCPG-PhysioMed, Oct 2013, Illkirch, France. 2013, 2nd Annual Meeting of the GDR RCPG-PhysioMed. ⟨hal-02745908⟩
  • Massimiliano Beltramo, V. Aucagne, R. Vincent, M. Galibert, J.B. Madinier, et al.. La kisspeptine : une nouvelle voie pour maitriser l’ovulation chez les petits ruminants ?. 5. Journées d'Animation Scientifique du département Phase (JAS Phase 2013), Oct 2013, Paris, France. 2013. ⟨hal-02805330⟩
  • Mathieu Galibert, Chrystelle Derache, Franck Coste, Hervé Meudal, Anne-Christine Lalmanach, et al.. Improvement of the chemical production of β-defensins including straightforward attribution of disulfide bridges. 18. Réunion du GFPP, May 2013, Sète, France. 1 p., 2013. ⟨hal-02805308⟩
  • M. Galibert, Chrystelle Derache, F. Coste, H. Meudal, Anne-Christine Lalmanach, et al.. Improvement of the chemical production of β-defensins including straighforward attribution of disulfide bridges. 3. International Symposium on Antimicrobial Peptides: Today knowledge and future applications, Jun 2012, Lille, France. , pp.C-43, 2012, AMP 2012 - Antimicrobial peptide symposium. ⟨hal-02748134⟩
  • Chrystelle Derache, Emmanuel Kut, Hervé Meudal, Vincent Aucagne, Agnès Delmas, et al.. Antibacterial spectrum of avian defensin 2: peculiarities in relationship with structural features. 3. International Symposium on Antimicrobial Peptides: Today knowledge and future applications (AMP 2012), Jun 2012, Lille, France. , pp.D-97, 2012. ⟨hal-02807349⟩
  • Chrystelle Derache, Hervé Meudal, Vincent Aucagne, Anne-Christine Lalmanach, Céline Landon, et al.. Synthesis and oxidative folding of functional miniproteins containing three disulfide bridges. 21e Colloque Biotechnocentre, 2008, Seillac, France. 1 p, 2008. ⟨hal-02818274⟩

Chapitre d'ouvrage2 documents

  • S. Abboud, A.F. Delmas, V. Aucagne. Solid phase chemical ligation. Brik Asharf, Dawson Philip, Liu Lei. Total Chemical Protein Synthesis, Wiley, 2021, 978-3-527-34660-8. ⟨hal-02974365⟩
  • Vincent Aucagne. (9H‐Fluoren‐9‐yl)methanethiol. Encyclopedia of Reagents for Organic Synthesis, John Wiley & Sons, Ltd, 2011, ⟨10.1002/047084289X.rn01287⟩. ⟨hal-02071829⟩

Brevet3 documents

  • Nicolas Guyot, Sophie Réhault-Godbert, Anne Silvestre, Sascha Trapp, Sophie Iochmann, et al.. Peptides dérivés d'une beta-défensine 11 aviaire et leurs utilisations. France, N° de brevet: WO 2020/030773 A1. AMV; SA, 3IMo, AIM. 2020. ⟨hal-02595638⟩
  • Massimiliano Beltramo, Vincent Aucagne, Alain Caraty, Agnès Delmas, Mathieu Galibert. KISS1R receptor agonist compounds and use thereof for inducing ovulation in mammals. Patent n° : WO2014118318 (A1). 2014, 49 p. + 12 p. annexes. ⟨hal-02793004⟩
  • Massimiliano Beltramo, Vincent Aucagne, Alain Caraty, Agnès Delmas. Composés agonistes du récepteur KISS1R et leur utilisation pour induire l’ovulation chez les mammiféres. N° de brevet: FR3001455 (A1). 2013, 34 p. + 10 p. annexes. ⟨hal-02808772⟩

Pré-publication, Document de travail1 document

  • El Hadji Cisse, Vincent Aucagne. A straightforward method to prevent the under-estimated problem of aspartimide formation during chemical ligation-mediated protein synthesis. 2024. ⟨hal-04797697⟩

Documents récupérés de l'archive ouverte HAL logo

 

BOUDVILLAIN Marc

email : marc.boudvillain[remplacer_par_at]cnrs-orleans.fr

Phone : +33 2.38.25.55.85

Research Director, Co-leader of the department “Molecular, Structural and Chemical Biology” and Leader of the team “RNA Remodeling Factors and Mechanisms”

CV and publications of Marc BOUDVILLAIN


75 documents

Article dans une revue48 documents

  • Mildred Delaleau, Nara Figueroa-Bossi, Thuy Duong Do, Patricia Kerboriou, Eric Eveno, et al.. Rho-dependent transcriptional switches regulate the bacterial response to cold shock. Molecular Cell, 2024, ⟨10.1016/j.molcel.2024.07.034⟩. ⟨hal-04678012⟩
  • Sarah Worthan, Robert Mccarthy, Mildred Delaleau, Ryan Stikeleather, Benjamin Bratton, et al.. Evolution of pH-sensitive transcription termination in Escherichia coli during adaptation to repeated long-term starvation. Proceedings of the National Academy of Sciences of the United States of America, 2024, 121 (39), ⟨10.1073/pnas.2405546121⟩. ⟨hal-04765566⟩
  • Vladimir Bidnenko, Arnaud Chastanet, Christine Péchoux, Yulia Redko-Hamel, Olivier Pellegrini, et al.. Complex sporulation-specific expression of transcription termination factor Rho highlights its involvement in Bacillus subtilis cell differentiation. Journal of Biological Chemistry, 2024, 300 (12), pp.107905. ⟨10.1016/j.jbc.2024.107905⟩. ⟨hal-04773401⟩
  • Emmanuel Saridakis, Rishi Vishwakarma, Josephine Lai-Kee-Him, Kevin Martin, Isabelle Simon, et al.. Cryo-EM structure of transcription termination factor Rho from Mycobacterium tuberculosis reveals bicyclomycin resistance mechanism. Communications Biology, 2022, 5 (1), pp.120. ⟨10.1038/s42003-022-03069-6⟩. ⟨hal-03563179⟩
  • Gauthier Roy, Antoine Rudy, Annie Schwartz, Stéphanie Slupek, Alex Rivera-Millot, et al.. Posttranscriptional Regulation by Copper with a New Upstream Open Reading Frame. mBio, 2022, ⟨10.1128/mbio.00912-22⟩. ⟨hal-03759142v2⟩
  • Mildred Delaleau, Eric Eveno, Isabelle Simon, Annie Schwartz, Marc Boudvillain. A scalable framework for the discovery of functional helicase substrates and helicase-driven regulatory switches. Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (38), ⟨10.1073/pnas.2209608119⟩. ⟨hal-03800009⟩
  • Isabelle Simon, Mildred Delaleau, Annie Schwartz, Marc Boudvillain. A large insertion domain in the Rho factor from a low G+C, Gram-negative bacterium is critical for RNA binding and transcription termination activity. Journal of Molecular Biology, 2021, 433 (15), pp.167060. ⟨10.1016/j.jmb.2021.167060⟩. ⟨hal-03248336⟩
  • Lionello Bossi, Nara Figueroa-Bossi, Philippe Bouloc, Marc Boudvillain. Regulatory interplay between small RNAs and transcription termination factor Rho. Biochimica et Biophysica Acta - Gene Regulatory Mechanisms , 2020, pp.194546. ⟨10.1016/j.bbagrm.2020.194546⟩. ⟨hal-02533337⟩
  • Cédric Nadiras, Mildred Delaleau, Annie Schwartz, Emmanuel Margeat, Marc Boudvillain. A Fluorogenic Assay To Monitor Rho-Dependent Termination of Transcription. Biochemistry, 2019, 58 (7), pp.865-874. ⟨10.1021/acs.biochem.8b01216⟩. ⟨hal-02067416⟩
  • Lionello Bossi, Mathilde Ratel, Camille Laurent, Patricia Kerboriou, Andrew Camilli, et al.. NusG prevents transcriptional invasion of H-NS-silenced genes. PLoS Genetics, 2019, 15 (10), pp.e1008425. ⟨10.1371/journal.pgen.1008425⟩. ⟨hal-02308418⟩
  • Cédric Nadiras, Eric Eveno, Annie Schwartz, Nara Figueroa-Bossi, Marc Boudvillain. A multivariate prediction model for Rho-dependent termination of transcription. Nucleic Acids Research, 2018, 46 (16), pp.8245 - 8260. ⟨10.1093/nar/gky563⟩. ⟨hal-01880575⟩
  • Odil Porrua, Marc Boudvillain, Domenico Libri. Transcription Termination: Variations on Common Themes. Trends in Genetics, 2016, 32 (8), pp.508 - 522. ⟨10.1016/j.tig.2016.05.007⟩. ⟨hal-01407669⟩
  • V. Gocheva, Antoine Le Gall, M. Boudvillain, E. Margeat, Marcelo Nollmann. Direct observation of the translocation mechanism of transcription termination factor Rho. Nucleic Acids Research, 2015, 43 (4), pp.2367-2377. ⟨10.1093/nar/gkv085⟩. ⟨hal-01171254⟩
  • F. d'Heygere, A. Schwartz, F. Coste, B. Castaing, M. Boudvillain. ATP-dependent motor activity of the transcription termination factor Rho from Mycobacterium tuberculosis. Nucleic Acids Research, 2015, 43 (12), pp.6099-60111. ⟨10.1093/nar/gkv505⟩. ⟨hal-01171219⟩
  • Emilie Soares, Annie Schwartz, Marcelo Nollmann, Emmanuel Margeat, Marc Boudvillain. The RNA-mediated, asymmetric ring regulatory mechanism of the transcription termination Rho helicase decrypted by time-resolved nucleotide analog interference probing (trNAIP).. Nucleic Acids Research, 2014, 42 (14), pp.9270-9284. ⟨10.1093/nar/gku595⟩. ⟨hal-01180888⟩
  • Nara Figueroa-Bossi, Annie Schwartz, Benoît Guillemardet, François d'Heygere, Lionello Bossi, et al.. RNA remodeling by bacterial global regulator CsrA promotes Rho-dependent transcription termination. Genes and Development, 2014, 28 (11), pp.1239-1251. ⟨10.1101/gad.240192.114⟩. ⟨hal-01178971⟩
  • Rachid Menouni, Stéphanie Champ, Leon Espinosa, Marc Boudvillain, Mireille Ansaldi. Transcription termination controls prophage maintenance in Escherichia coli genomes.. Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (35), pp.14414-9. ⟨10.1073/pnas.1303400110⟩. ⟨hal-00874882⟩
  • Francesca Fiorini, Marc Boudvillain, Hervé Le Hir. Tight intramolecular regulation of the human Upf1 helicase by its N- and C-terminal domains. Nucleic Acids Research, 2013, 41 (4), pp.2404-2415. ⟨10.1093/nar/gks1320⟩. ⟨hal-02358926⟩
  • Marc Boudvillain, Nara Figueroa-Bossi, Lionello Bossi. Terminator still moving forward: expanding roles for Rho factor.. Current Opinion in Microbiology, 2013, 16 (2), pp.118-24. ⟨10.1016/j.mib.2012.12.003⟩. ⟨hal-00840158⟩
  • François d'Heygère, Makhlouf Rabhi, Marc Boudvillain. Phyletic distribution and conservation of the bacterial transcription termination factor Rho.. Microbiology, 2013, epub ahead of print. ⟨10.1099/mic.0.067462-0⟩. ⟨hal-00840167⟩
  • Annie Schwartz, Makhlouf Rabhi, Emmanuel Margeat, Marc Boudvillain. Analysis of helicase-RNA interactions using nucleotide analog interference mapping.. Methods in Enzymology, 2012, 511, pp.149-69. ⟨10.1016/B978-0-12-396546-2.00007-3⟩. ⟨hal-00726256⟩
  • Lionello Bossi, Annie Schwartz, Benoit Guillemardet, Marc Boudvillain, Nara Figueroa-Bossi. A role for Rho-dependent polarity in gene regulation by a noncoding small RNA.. Genes and Development, 2012, 26 (16), pp.1864-1873. ⟨10.1101/gad.195412.112⟩. ⟨hal-00727260⟩
  • Makhlouf Rabhi, Olivier Espéli, Annie Schwartz, Bastien Cayrol, a Rachid Rahmouni, et al.. The Sm-like RNA chaperone Hfq mediates transcription antitermination at Rho-dependent terminators.. EMBO Journal, 2011, 30 (14), pp.2805-16. ⟨10.1038/emboj.2011.192⟩. ⟨hal-00720713⟩
  • Makhlouf Rabhi, Veronika Gocheva, Frederique Jacquinot, Andrea Lee, Emmanuel Margeat, et al.. Mutagenesis-Based Evidence for an Asymmetric Configuration of the Ring-Shaped Transcription Termination Factor Rho. Journal of Molecular Biology, 2011, 405 (2), pp.497-518. ⟨10.1016/j.jmb.2010.11.006⟩. ⟨hal-00608241⟩
  • Marc Boudvillain, Marcelo Nollmann, Emmanuel Margeat. Keeping up to speed with the transcription termination factor Rho motor.. Transcription, 2010, 1 (2), pp.70-75. ⟨10.4161/trns.1.2.12232⟩. ⟨hal-00591655⟩
  • Makhlouf Rabhi, Roman Tuma, Marc Boudvillain. RNA remodeling by hexameric RNA helicases. RNA Biology, 2010, 7 (6 - Sp. Iss. SI), pp.655-666. ⟨10.4161/rna.7.6.13570⟩. ⟨hal-00602496⟩
  • Annie Schwartz, Makhlouf Rabhi, Frederique Jacquinot, Emmanuel Margeat, A. Rachid Rahmouni, et al.. A stepwise 2 '-hydroxyl activation mechanism for the bacterial transcription termination factor Rho helicase. Nature Structural and Molecular Biology, 2009, 16 (12), pp.1309-1316. ⟨10.1038/nsmb.1711⟩. ⟨hal-00525325⟩
  • Annie Schwartz, Céline Walmacq, A. Rachid Rahmouni, Marc Boudvillain. Noncanonical Interactions in the Management of RNA Structural Blocks by the Transcription Termination Rho Helicase. Biochemistry, 2007, 46 (33), pp.9366 - 9379. ⟨10.1021/bi700493m⟩. ⟨hal-00166551⟩
  • Annie Schwartz, Emmanuel Margeat, A. Rachid Rahmouni, Marc Boudvillain. Transcription termination factor Rho can displace streptavidin from biotinylated RNA. Journal of Biological Chemistry, 2007, 282 (43), pp.31469-31476. ⟨10.1074/jbc.M706935200⟩. ⟨hal-00176284⟩
  • C. Walmacq, A.R. Rahmouni, M. Boudvillain. Testing the steric exclusion model for hexameric helicases: substrate features that alter RNA-DNA unwinding by the transcription termination factor Rho. Biochemistry, 2006, 45, pp.5885-5895. ⟨10.1021/bi0600648⟩. ⟨hal-00088941⟩
  • C. Walmacq, A.R. Rahmouni, M. Boudvillain. Influence of substrate composition on the helicase activity of transcription termination factor Rho: reduced processivity of Rho hexamers during unwinding of RNA-DNA hybrid regions. Journal of Molecular Biology, 2004, 342 (2), pp.403-420. ⟨10.1016/j.jmb.2004.07.026⟩. ⟨hal-00113090⟩
  • A. Schwartz, A. Rachid Rahmouni, Marc Boudvillain. The functional anatomy of an intrinsic transcription terminator. EMBO Journal, 2003, 22 (13), pp.3385 - 3394. ⟨10.1093/emboj/cdg310⟩. ⟨hal-01880611⟩
  • Marc Boudvillain, Annie Schwartz, A. Rachid Rahmouni. Limited Topological Alteration of the T7 RNA Polymerase Active Center at Intrinsic Termination Sites †. Biochemistry, 2002, 41 (9), pp.3137-3146. ⟨10.1021/bi011358q⟩. ⟨hal-02075291⟩
  • Kathrin Schmidt, Marc Boudvillain, Annie Schwartz, Gijs van Der Marel, Jacques van Boom, et al.. Monofunctionallytrans-Diammine Platinum(II)-Modified Peptide Nucleic Acid Oligomers: A New Generation of Potential Antisense Drugs. Chemistry - A European Journal, 2002, 8 (24), pp.5566 - 5570. 3.0.CO;2-#">⟨10.1002/1521-3765(20021216)8:24<5566::AID-CHEM5566>3.0.CO;2-#⟩. ⟨hal-01880614⟩
  • Boudvillain Marc, Rozenn Dalbies-Tran, Marc Leng, Marc Boudvillain. Oligonucleotides Modified With Transplatin Derivatives: Fast and Efficient Metalloribozymes. Metal-Based Drugs, 2001, 8 (1), pp.39 - 45. ⟨10.1155/MBD.2001.39⟩. ⟨hal-01880601⟩
  • Marc Boudvillain, Alexandre de Lencastre, Anna Marie Pyle. A tertiary interaction that links active-site domains to the 5′ splice site of a group II intron. Nature, 2000, 406 (6793), pp.315 - 318. ⟨10.1038/35018589⟩. ⟨hal-01880615⟩
  • Jens Müller, Markus Drumm, Marc Boudvillain, Marc Leng, Einar Sletten, et al.. Parallel-stranded DNA with Hoogsteen base pairing stabilized by a trans-[Pt(NH3)2]2+ cross-link: characterization and conversion into a homodimer and a triplex. Journal of Biological Inorganic Chemistry, 2000, 5 (5), pp.603-611. ⟨10.1007/s007750000143⟩. ⟨hal-02075297⟩
  • Anna M. Pyle, V Chu, E Jankowsky, Marc Boudvillain. Using DNAzymes to cut, process, and map RNA molecules for structural studies or modification.. Methods in Enzymology, 1999, 317, pp.140-6. ⟨hal-02096724⟩
  • Françoise Paquet, Marc Boudvillain, Gérard Lancelot, Marc Leng. NMR solution structure of a DNA dodecamer containing a transplatin interstrand GN7-CN3 cross-link. Nucleic Acids Research, 1999, 27 (21), pp.4261-4268. ⟨10.1093/nar/27.21.4261⟩. ⟨hal-02075311⟩
  • Marc Boudvillain, Anna M. Pyle. Defining functional groups, core structural features and inter-domain tertiary contacts essential for group II intron self-splicing: a NAIM analysis. EMBO Journal, 1998, 17 (23), pp.7091-7104. ⟨10.1093/emboj/17.23.7091⟩. ⟨hal-02096717⟩
  • Marc Boudvillain, Martine Guerin, Rozenn Dalbies, Tula Saison-Behmoaras, Marc Leng. Transplatin-Modified Oligo(2‘- O -methyl ribonucleotide)s: A New Tool for Selective Modulation of Gene Expression †. Biochemistry, 1997, 36 (10), pp.2925 - 2931. ⟨10.1021/bi962695f⟩. ⟨hal-01880625⟩
  • C. Prevost, M. Boudvillain, P. Beudaert, M. Leng, R. Lavery, et al.. Distortions of the DNA double helix induced by 1,3-trans-diamminedichloroplatinum(II)-intrastrand cross-link: an internal coordinate molecular modeling study.. Journal of Biomolecular Structure and Dynamics, 1997, 14, pp.703-714. ⟨hal-00313421⟩
  • Caroline Colombier, Marc Boudvillain, Marc Leng. Interstrand Crosslinking Reaction in Transplatin-Modified Oligo-2‵-O-Methyl Ribonucleotide-RNA Hybrids. Antisense and Nucleic Acid Drug Development, 1997, 7 (4), pp.397-402. ⟨10.1089/oli.1.1997.7.397⟩. ⟨hal-02322135⟩
  • Eloy Bernal-Méndez, Marc Boudvillain, Francisco González-Vílchez, Marc Leng. Chemical Versatility of Transplatin Monofunctional Adducts within Multiple Site-Specifically Platinated DNA †. Biochemistry, 1997, 36 (24), pp.7281 - 7287. ⟨10.1021/bi9703148⟩. ⟨hal-01880622⟩
  • Marc Boudvillain, C. Prevost, P. Beudaert, M. Leng, R. Lavery, et al.. Distortions of the DNA Double Helix Induced by 1,3-trans-Diamminedichloroplatinum(II)-intrastrand Cross-link: An Internal Coordinate Molecular Modeling Study. Journal of Biomolecular Structure and Dynamics, 1997, 14 (6), pp.703 - 714. ⟨10.1080/07391102.1997.10508173⟩. ⟨hal-01880624⟩
  • Marc Boudvillain, Rozenn Dalbies, M. Leng. Evidences for a catalytic activity of the DNA double helix in the reaction between DNA, platinum(II), and intercalators.. Metal Ions in Biological Systems, 1996, 33, pp.87-104. ⟨hal-02322086⟩
  • Marc Boudvillain, Rozenn Dalbies, Christophe Aussourd, Marc Leng. Intrastrand cross-links are not formed in the reaction between transplatin and native DNA: relation with the clinical inefficency of transplatin. Nucleic Acids Research, 1995, 23 (13), pp.2381-2388. ⟨10.1093/nar/23.13.2381⟩. ⟨hal-02075318⟩
  • Rozenn Dalbies, Marc Boudvillain, Marc Leng. Linkage isomerization reaction of intrastrand cross-links in trans -diamminedichloroplatinum(II)-modified single-stranded oligonucleotides. Nucleic Acids Research, 1995, 23 (6), pp.949-953. ⟨10.1093/nar/23.6.949⟩. ⟨hal-02075321⟩

Communication dans un congrès6 documents

  • Thuy Duong Do, Mildred Delaleau, Eric Eveno, Marc Boudvillain. Genome-wide mapping of the targets of Rho-dependent termination of transcription in Mycobacterium tuberculosis. 36e Colloque Biotechnocentre, Oct 2024, Nouan le Fuzelier, France. ⟨hal-04765451⟩
  • Johnathan Black, Eric Eveno, Marc Boudvillain. Discovery of new riboswitches by very large-scale enzymatic screening. 36e Colloque Biotechnocentre, Oct 2024, Nouan Le Fuzelier, France. ⟨hal-04765527⟩
  • Thuy Duong Do, Mildred Delaleau, Eric Eveno, Marc Boudvillain. Towards genome-wide mapping of the targets of Rho-dependent termination of transcription in Mycobacterium tuberculosis. 35e Colloque Biotechnocentre, Oct 2023, Nouan Le Fuzelier, France. ⟨hal-04765504⟩
  • Marc Boudvillain. Régulation des gènes par un moteur moléculaire unique aux bactéries. 34e Colloque de Biotechnocentre, Oct 2022, Nouan-le-Fuzelier, France. ⟨hal-04148476⟩
  • Mildred Delaleau, Eric Eveno, Annie Schwartz, Isabelle Simon, Marc Boudvillain. Helicase-SELEX: A versatile new approach to seek constitutive or conditional helicase substrates at global scale. 12th SifrARN: Structure, integration, function & reactivity of RNA, Oct 2022, Bordeaux, France. ⟨hal-04148466⟩
  • Emmanuel Saridakis, Rishi Vishwakarma, Joséphine Lai Kee Him, Kevin Martin, Isabelle Simon, et al.. Structural basis for resistance of Mycobacterium tuberculosis Rho to bicyclomycin. Helicases & Nucleic Acid-Based Machines: Structure, Mechanism & Regulation, and Roles in HumanDisease, Jul 2021, Paris, France. ⟨hal-03419029⟩

Poster10 documents

  • Isabelle Simon, Mildred Delaleau, Annie Schwartz, Marc Boudvillain. Variation on a theme - the unusual features of the essential transcription termination Rho factor from a low G+C, Gram-negative bacterium. 45th FEBS congress, Jul 2021, Lubjana, Slovenia. ⟨hal-03419044⟩
  • I. Simon, A. Schwartz, M. Delaleau, L. Bossi, N. Figueroa-Bossi, et al.. Exploring Rho helicase activity for the purpose of synthetic regulation. 32e Colloque Biotechnocentre, Oct 2019, Seillac, France. ⟨hal-02902096⟩
  • E. Eveno, C. Nadiras, N. Figueroa-Bossi, A. Schwartz, M. Boudvillain. Predicting Rho-dependent termination of transcription at genome scale. 24th Annual Meeting of the RNA Society, Jun 2019, Cracovie, Poland. ⟨hal-02902104⟩
  • E. Eveno, C. Nadiras, A. Schwartz, N. Figueroa-Bossi, M. Boudvillain. Genome-scale prediction of Rho-dependent termination of transcription. 11e Rencontre SifrARN (SFBBM), Nov 2018, Nancy, France. ⟨hal-02902107⟩
  • C. Nadiras, E. Eveno, M. Boudvillain. Towards a model for predicting Rho-dependent transcription termination sites. Le Studium conference “Structural biology and biophysics of RNA-protein complexes”, Nov 2017, Orléans, France. ⟨hal-02902112⟩
  • C. Nadiras, E. Eveno, M. Boudvillain. Seeking Rho-dependent transcription termination sites within bacterial genomes. EMBO & Harden conference - Helicases and Nucleic Acid Translocases, Jul 2017, Kloster Banz-Bamberg, Germany. ⟨hal-02902120⟩
  • C. Nadiras, E. Eveno, M. Boudvillain. Identification des sites de terminaison de transcription Rho-dépendantes dans les génomes bactériens. 30e Colloque Biotechnocentre, Oct 2017, Seillac, France. ⟨hal-02902116⟩
  • C. Clerte, O. Manier, J-B. Fiche, M. Boudvillain, L. Bossi, et al.. Relationships between Rho and RNA polymerase in living bacteria. Le Studium conference “Structural biology and biophysics of RNA-protein complexes”, Nov 2017, Orléans, France. ⟨hal-02902111⟩
  • R. Vishwakarma, A. Nord, F. Pedaci, M. Boudvillain, E. Margeat. Single-molecule analysis of E. coli Rho translocase, Helicase, transcription termination activities, and its interactions with RNA polymerase. Le Studium conference “Structural biology and biophysics of RNA-protein complexes”, Nov 2017, Orléans, France. ⟨hal-02902115⟩
  • C. Nadiras, Eric Eveno, A. Schwartz, M. Boudvillain. Analyse des terminateurs Rho-dépendants bactériens. 29e colloque Biotechnocentre, Oct 2016, Seillac, France. ⟨hal-02453368⟩

Ouvrage (y compris édition critique et traduction)1 document


Chapitre d'ouvrage8 documents

  • Isabelle Simon, Marc Boudvillain. A simple fluorescence microplate assay to monitor RNA-DNA hybrid unwinding by the bacterial transcription termination factor Rho. Marc Boudvillain. RNA remodeling proteins : Methods and Protocols, 2209, Humana press, pp.143-161, 2021, Methods in Molecular Biology, 978-1-0716-0937-8. ⟨10.1007/978-1-0716-0935-4_10⟩. ⟨hal-03036494⟩
  • Cédric Nadiras, Annie Schwartz, Mildred Delaleau, Marc Boudvillain. Evaluating the Effect of Small RNAs and Associated Chaperones on Rho-Dependent Termination of Transcription In Vitro.. Methods in Mecular Biology, 1737, humana press, Totowa, NJ-USA, pp.99-118, 2018, Bacterial regulatory RNA (Arluison & Valverde, eds), ⟨10.1007/978-1-4939-7634-8_7⟩. ⟨hal-01880631⟩
  • F. d'Heygère, A. Schwartz, F. Coste, B. Castaing, M. Boudvillain. Monitoring RNA Unwinding by the Transcription Termination Factor Rho from Mycobacterium tuberculosis. Methods in Mecular Biology, 1259, Springer, pp.293-311, 2015, RNA remodelling proteins (Boudvillain, ed), 978-1-4939-2213-0. ⟨10.1007/978-1-4939-2214-7_18⟩. ⟨hal-01174055⟩
  • Olga Fedorova, Marc Boudvillain, Christina Waldsich. Nucleotide Analog Interference Mapping and Suppression (NAIM/NAIS): a Combinatorial Approach to Study RNA Structure, Folding, and Interaction with Proteins. Handbook of RNA Biochemistry, 2nd edition (Westhof, Bindereif, Schon & Hartmann, eds), Wiley-VCH Verlag GmbH & Co. KGaA, pp.329-368, 2014, ⟨10.1002/9783527647064.ch17⟩. ⟨hal-02097735⟩
  • Makhlouf Rabhi, Rahmouni Rachid A., Marc Boudvillain. Transcription termination factor Rho: a ring-shaped RNA helicase from bacteria. Eckhard Jankowsky. RNA helicases, Royal Society of Chemistry Publishing, pp.243-271, 2010, ⟨10.1039/9781849732215-00243⟩. ⟨hal-00610004⟩
  • Marc Boudvillain, Céline Walmacq, Annie Schwartz, Frédérique Jacquinot. Simple enzymatic assays for the in vitro motor activity of transcription termination factor Rho from Escherichia coli. Mohamed M. M. Abdelhaleem. Methods in Mecular Biology, Humana Press, pp.137-154, 2009, Helicases (Abdelhaleem, ed), ⟨10.1007/978-1-60327-355-8_10⟩. ⟨hal-00623571⟩
  • O. Fedorova, M. Boudvillain, J. Kawaola, A.M. Pyle. Nucleotide analog interference mapping and suppression (NAIM/NAIS): specific applications in studies of RNA tertiary structure, dynamic helicase mechanism, and RNA-protrein interactions. E. Westhof, A. Bindereif, A. Schon, R.I. Hartmann. Handbook of RNA biochemistry, Wiley-VCH, pp.259-293, 2005. ⟨hal-00088591⟩
  • Marc Boudvillain, Rozenn Dalbies-Tran, Leng M.. Trans-Diamminedichloroplatinum (II) Is Not an Antitumor Drug: Why?. Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy, 2, Plenum Press, New'Tork, USA, pp.17-25, 1996. ⟨hal-02097755⟩

Brevet1 document

  • Marc Leng, Rozenn Dalbies, Marc Boudvillain. Procédé de pontage sélectif et irréversible d'oligonucléotides platinés sur de l'ARN et ses applications. France, Patent n° : WO1998018915A2. 1996. ⟨hal-02097839⟩

Pré-publication, Document de travail1 document

  • Sarah Worthan, Robert Mccarthy, Mildred Delaleau, Ryan Stikeleather, Benjamin Bratton, et al.. Evolution of pH-sensitive transcription termination during adaptation to repeated long-term starvation. 2024. ⟨hal-04576292⟩

Documents récupérés de l'archive ouverte HAL logo