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Bispidines and manganese: a winning couple
Today manganese(II) is the most promising candidate to replace gadolinium towards safer and more biocompatible MRI contrast agents. However, its selective complexation versus other essential metal ions, such as zinc, remains very challenging
Marcin Suskiewicz, research fellow at the CBM, obtained an ERC Starting 2022 grant
To understand SUMOylation, a reaction that regulates the functions of many proteins
2022, November 25 - Seminar of doctor Marc Graille
"The devil is in the methyl : Generation and degradation of methylated RNAs"
2022, November 18 - Seminar of Dr Bojan Zunar
"Yeast Saccharomyces cerevisiae as a next-generation eukaryotic whole-cell copper biosensor and its interaction with thermally-reversible Pluronic F127-based hydrogel"
CBM PhD students have talent!
3 PhD students awarded
A major advance in the understanding of DNA damage repair
A CBM team has just revealed how DNA glycosylases in archaea recognize and repair certain lesions in their DNA.
Welcome to the 9 PhD students of the 2022-2023 class!
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2022, October, 14: Seminar of Manon Isaac
"Tools for zinc detection"
Identification of a ‘double‘ protein post-translational modification
A team of scientists, including members of the CBM in Orléans, led by groups at the University of Oxford, has identified a potential new ‘double’ protein post-translational modification, changing the way we think about protein regulation.
4th scientific days of the GDR AIM
2022, October 3-5 - Centre International Universitaire pour la Recherche - Orléans
A versatile new approach to seek constitutive or conditional helicase substrates at global scale
Helicase-SELEX is a new screening scheme allowing global discovery of functional helicase substrates, deep probing of helicase specificity, and development of synthetic sensors/regulatory switches based on helicase activity
2022, October 7 - Seminar of Jacob Elmer Associate Professor
"Overcoming Host Cell Defenses against Gene Therapy"
2022, September 28 - Seminar of Prof. Józef Dulak
"Induced pluripotent stem cells for cardiac disease modelling
and experimental therapy of heart failure"
Eva Jakab Toth receives the “Torsten Almén” Award
This award recognizes her pioneering research on paramagnetic MRI contrast agents
September 20, 2022 - Seminar from Dr André F. Martins
"Imaging metabolism non-invasively in vivo"
August 30th, 2022 in Orleans
Professor Vincent L. Pecoraro of the University of Michigan is invited at the CBM from May to August 2022 through a LE STUDIUM Research Professorship
Professor Pecoraro, a world expert in the field of bioinorganic chemistry, has joined the research team “Luminescent lanthanide compounds, optical spectroscopy and bioimaging” to enhance their collaboration on lanthanide-based metallacrowns emitting in the near-infrared domain for bioimaging applications.
Biotechnocentre 34th conference - October 20 and 21, 2022
Meetings in the fields of Life Sciences, Health and Well-being in the Center-Val de Loire Region
7th Biotechnocentre theme day – June 17, 2022
Exposome et épigénétique - Comment l'environnemnt "se joue" de nos gènes ?
In Cellulo and In Vivo Comparison of 3 helper lipids for Lipid Nanoparticle Formulation of mRNA
mRNA-LNPs prepared with DOPE and β-sitosterol were more efficient for mRNA transfection in murine dendritic cells than LNPs containing DSPC; this higher potency of DOPE and β-sitosterol LNPs for mRNA expression was also evident in vivo