Typologie d'actualités: Team Chemistry, Imaging and Exobiology

2024 edition of “The Future of Molecular MR” international conference

The "Metal complexes and MRI" group of CBM is organizing the 2024 edition of "The Future of Molecular MR" meeting in Orléans which will gather 120 participants from over the world.

The objectives of this international conference are to establish current state of the art in molecular MR and pinpoint knowledge gaps, to identify adjacent technologies that can be combined with molecular MRI to create more accurate, ensitive, rapid and quantitative methods, and to bring leaders from different fields to challenge orthodoxy and identify new opportunities in molecular MR.

The meeting will take place in Hotel Dupanloup, Orléans, 17-20 June 2024.

Congress website

 

 

Professor Vincent L. Pecoraro of the University of Michigan is invited at the CBM from May to July 2024 through a LE STUDIUM Research Professorship

Professor Pecoraro is internationally recognized for his major contributions in bioinorganic chemistry, notably on the role of manganese complexes and clusters in photosynthetic water oxidation. He is also a pioneer in the design of metalloenzyme mimetics and in the study of metallacrown complexes with unique magnetic and/or luminescence properties for developments in medical imaging, a field in which several patents have recently been filed with the team “Luminescent lanthanide compounds, optical spectroscopy and bioimaging” from the CBM.

In 2021, he received an honorary doctorate from the University of Aix-Marseille and a LE STUDIUM Research Professorship (Loire Valley Institute). In addition, Professor Pecoraro is the 2021 recipient of the Franco-American award from the American Chemical Society and the “Société Chimique de France”.

He is one of the co-founder of the startup VIEWaves founded in Orléans in March 2022 that aims at the commercialization of the optical imaging agents emitting in the near-Infrared domain created on the basis of the collaborative work conducted with the team at CBM.

Dual agents for non-invasive imaging of living organisms

Researchers in the "Lanthanide Luminescent Compounds, Spectroscopy and Optical Bioimaging" team have designed a molecular probe that can image living organisms using both near-infrared (NIR) luminescence and photoacoustic (PA) signal detection. These two complementary imaging techniques make it possible to monitor biological events precisely, in real time and non-invasively.

Find out more

A Dual-Mode Near-Infrared Optical and Photoacoustic Imaging Agent Based on a Low Energy Absorbing Ytterbium Complex
Anton Kovalenko, Svetlana V. Eliseeva, Guillaume Collet, Saïda El Abdellaoui, Sharuja Natkunarajah, Stéphanie Lerondel, Laure Guénée, Céline Besnard & Stéphane Petoud
JACS 2024
https://doi.org/10.1021/jacs.4c03406

Breast cancer: towards early diagnosis by imaging

In vivo imaging of metastatic breast cancer tumors at very early stages is about to become possible. A team of chemists and biologists from the Center for Molecular Biophysics (CNRS) has indeed developed a new magnetic resonance imaging (MRI) probe which has a selective affinity for an emerging biomarker of metastatic breast cancer: Netrin- 1. Find out more on the Cnrs Chimie website.

See more and Cnrs Chmie website.

Reference
Peptide-Conjugated MRI Probe Targeted to Netrin-1, a Novel Metastatic Breast Cancer Biomarker
Clémentine Moreau, Tea Lukačević, Agnès Pallier, Julien Sobilo, Samia Aci-Sèche, Norbert Garnier, Sandra Même, Éva Tóth & Sara Lacerda
Bioconjugate Chemistry 2024
https://doi.org/10.1021/acs.bioconjchem.3c00558