Typologie d'actualités: Team Molecular, Structural and Chemical Biology

21st Congress of the French Group of Peptides and Proteins (GFPP)

The next meeting of the French peptide and protein group will take place in Amboise (Villa Bellagio), from Sunday 12 to Thursday 16 May 2019, in the beautiful and historic Loire Valley.

It should be noted that 2019 will mark the 41st anniversary of the creation of the GFPP and also the 500th anniversary of the death of Leonardo da Vinci, who spent his last years in Amboise, at the Château du Clos-Lucé, located a few kilometers from the center conferences.

The conference program covers cutting-edge topics in the field of peptides and proteins.

Learn more.

 

 

29th Congress of the Society of Environmental Toxicology and Chemistry (SETAC)

This event covering European area focusses on:

One Environment, One Health. Sustainable Societies.

Jean-Marc Bonmatin has been invited to present his scientific findings during a special session, including some observations on socio-philosophic aspects, entitled: Your Science or My Science? When the Sides Taken on a Research Topic are Impacted by Different Philosophical Positions and Values

See the programm

CBM researchers have created the first method for detecting non-covalent complexes of biomolecules by MALDI mass spectrometry based on liquid deposits

The success of this method relies on the use of nonvolatile liquid matrices, which avoids the passage through the solid phase conventionally used in MALDI and the denaturation of the non-covalent assemblies. By their increased viscosity, these matrices also have the advantage of better mimicking the cluttered environments of living organisms.
The reliability of this method has been shown for non-covalent protein protein and ligand protein systems. This new approach could be used for screening of therapeutic protein ligands and facilitating the analysis of membrane protein complexes by mass spectrometry.

The first computational method to predict Rho-dependent termination of transcription.

Rho-dependent termination is a specific bacterial mechanism, which plays a major role in gene expression and maintenance of genomic integrity. This is an important mechanism for the fast adaptation of bacteria to environmental changes or stresses. Although Rho-dependent termination sites are very diverse and without a real consensus sequence, CBM researchers have identified dozens of quantitative sequence descriptors (eg% C and% G) that, taken collectively, provide good prediction of the sites of Rho action in the model genomes of Escherichia coli and Salmonella (85% success rate).

This work was published in the journal Nucleic Acids Research.