The League Against Cancer supports research carried out at the CBM and the INEM

The committees of the Grand Ouest Cancer League bringing together Brittany, Pays de la Loire, Centre-Val de Loire and Poitou-Charentes pool their resources to support cancer researchers.

On Tuesday 7 February at the CBM, La Ligue contre le cancer officially presented a check for €146,000 to support 6 teams of researchers from the CBM and the INEM (Laboratory of Experimental and Molecular Immunology and Neurogenetics). The projects supported aim to quickly achieve concrete results for the benefit of patients.

The committees of Loiret (represented by its volunteer Administrator, Doctor Jean-Louis Vaur) and Eure-et-Loir (represented by its volunteer Vice-President Mr. Jacques Dautreme) were present. The Loir-et-Cher, Cher and Morbihan committees, which are also funders, could not be present but indicated that they were happy to be able to contribute to the financing of regional research.

Mr. Jean-Marc Schneider from La République du Center came to immortalize this moment by going around the table allowing everyone to present their project as well as the benefits and progress to come.

Marcin Suskiewicz, research fellow at the CBM, obtained an ERC Starting 2022 grant

SUMOylation is a natural reaction that changes the structure of proteins in cells. Thanks to his ERC SUMOwriteNread project, Marcin Suskiewicz of the CBM wants to characterize the mechanism by which it occurs, as well as its effects on the properties of proteins. This reaction remains poorly understood even though it probably plays an essential role in our cells.

Find out more on the CNRS Institute of Chemistry website

CBM PhD students have talent!

Ons Kharrat, from the "NMR of Biomolecules" group, received one of the 3 prizes for the best oral communication at the GDR MuFoPAM days which took place from October 19 to 21, 2022.
This prize was awarded to him by the company Genepep (https://www.genepep.com/accueil/).

Elodie Villalonga, from the "Cell signaling and neurofibromatosis" group, won one of the 2 prizes for the best oral communication
and
Valentin Beauvais, from the group “Dysregulation of autophagy during inflammation due to HIV”, received one of the poster prizes at the 34th Biotechnocentre conference which took place on October 20 and 21, 2022.

A major advance in the understanding of DNA damage repair

The "DNA repair: structure, function and dynamics" team has just revealed, in the prestigious journal Nucleic Acid Research, how archaeal DNA glycosylases are able to recognize and repair, at the molecular level, certain lesions in their DNA.

To know more :
Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing
Coste Franck, Goffinont Stéphane, Cros Julien, Gaudon Virginie, Guérin Martine, Garnier Norbert, Confalonieri Fabrice, Flament Didier, Suskiewicz Marcin Josef, Castaing Bertrand https://doi.org/10.1093/nar/gkac932