Molecular, Structural and Chemical Biology Department

The department brings together scientists from diverse disciplines (chemistry, biology, biophysics) sharing a common molecular language.

Department leaders: Céline LANDON and Marc BOUDVILLAIN

The projects carried out in the team aim at understanding fundamental molecular mechanisms underlying the activity and regulation of biomolecules. Fundamental advances in chemistry, biochemistry, biophysics and molecular biology are used to probe living systems at a molecular level and to exploit the results to design new strategies in human therapy and new tools for biology. The team is organized into five thematic groups and manages the CBM's NMR and Mass Spectrometry platforms.

Synthetic protein and bioorthogonal chemistry

Team leader: Vincent AUCAGNE

RNA Remodeling Factors and Mechanisms

Group leader: Marc BOUDVILLAIN

Functional Mass Spectrometry of Molecular Assemblies

Team leader: Martine CADÈNE

Cell signalling and neurofibromatosis

Team leaders: Hélène BÉNÉDETTI and Béatrice VALLÉE

Post-translational modifications of proteins and DNA repair: structure, function and dynamic

Team leader: Bertrand CASTAING, Co-leader : Marcin Suskiewicz

NMR of biomolecules

Team leader: Céline LANDON

Impact of pesticides on environment, biodiversity and public health

Jean-Marc BONMATIN